Detailed information for compound 1564991

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 447.503 | Formula: C25H21NO5S
  • H donors: 1 H acceptors: 3 LogP: 5.15 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)ccc(c2)S(=O)(=O)Nc1ccc(cc1)c1ccc(cc1)C(=O)OC
  • InChi: 1S/C25H21NO5S/c1-30-23-13-9-21-16-24(14-10-20(21)15-23)32(28,29)26-22-11-7-18(8-12-22)17-3-5-19(6-4-17)25(27)31-2/h3-16,26H,1-2H3
  • InChiKey: SQXJOYBFNAPUTR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens plasminogen activator, urokinase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus Mastin plasminogen activator, urokinase 414 aa 340 aa 24.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Probable DNA topoisomerase II 0.0107 0.1252 0.3575
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0065 0.0384
Entamoeba histolytica DNA topoisomerase II, putative 0.0107 0.1252 0.2939
Loa Loa (eye worm) hypothetical protein 0.0011 0.0049 0.014
Loa Loa (eye worm) tubulin beta-4 chain 0.0032 0.0317 0.0906
Loa Loa (eye worm) tubulin gamma chain 0.0032 0.0317 0.0906
Echinococcus granulosus tubulin alpha 3 chain 0.0032 0.0317 0.0437
Schistosoma mansoni tubulin subunit alpha 0.0032 0.0317 0.0437
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0451 0.1353
Schistosoma mansoni potassium channel beta 0.0019 0.0153 0.0211
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0267 0.0368
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0051 0.0119
Schistosoma mansoni ets-related 0.022 0.265 0.3652
Chlamydia trachomatis DNA gyrase subunit B 0.0049 0.0531 0.7584
Brugia malayi steroid hormone receptor 0.0009 0.0023 0.0067
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0008 0.0018 0.0042
Leishmania major P-type H -ATPase, putative 0.0008 0.0018 0.0106
Onchocerca volvulus 0.0043 0.0451 0.3264
Loa Loa (eye worm) hypothetical protein 0.0015 0.01 0.0284
Echinococcus granulosus beta tubulin 0.0032 0.0317 0.0437
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0798 0.0798
Brugia malayi nuclear hormone receptor 0.0009 0.0023 0.0067
Entamoeba histolytica alcohol dehydrogenase, putative 0.0019 0.0153 0.0359
Echinococcus multilocularis phosphoserine phosphatase 0.0008 0.0018 0.0018
Echinococcus granulosus beta tubulin 0.0032 0.0317 0.0437
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0008 0.0018 0.0053
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0008 0.0018 0.0106
Echinococcus granulosus cation transporting ATPase 13A1 0.0008 0.0018 0.0025
Schistosoma mansoni patched 1 0.0041 0.0426 0.0587
Brugia malayi Tubulin beta-1 chain 0.0032 0.0317 0.0906
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0059 0.0139
Brugia malayi hypothetical protein 0.002 0.016 0.0458
Loa Loa (eye worm) oxidoreductase 0.0066 0.0734 0.2095
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0008 0.0018 0.0106
Trichomonas vaginalis DNA topoisomerase II, putative 0.0107 0.1252 0.2939
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.001 0.0014
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0066 0.0734 0.1722
Leishmania major DNA damage repair protein, putative 0.0012 0.0065 0.0384
Onchocerca volvulus 0.0023 0.0203 0.1468
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0035 0.0205
Mycobacterium ulcerans hypothetical protein 0.0023 0.0202 0.0597
Schistosoma mansoni hypothetical protein 0.0029 0.0278 0.0384
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.001 0.0014
Echinococcus granulosus nibrin 0.001 0.0035 0.0048
Echinococcus multilocularis muscleblind protein 0.0121 0.1424 0.1424
Trichomonas vaginalis tubulin gamma chain, putative 0.0032 0.0317 0.0745
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0301 0.0706
Brugia malayi beta-lactamase 0.0043 0.0451 0.1288
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0734 0.1011
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0051 0.0119
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0202 0.0597
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0398 0.2335
Trypanosoma brucei beta tubulin 0.0032 0.0317 0.1863
Plasmodium vivax DNA topoisomerase II, putative 0.0107 0.1252 0.7353
Loa Loa (eye worm) hypothetical protein 0.0028 0.0267 0.0762
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0817 0.2332
Brugia malayi Glycosyl hydrolases family 31 protein 0.0012 0.0059 0.0169
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0008 0.0018 0.0025
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0008 0.0018 0.0053
Loa Loa (eye worm) hypothetical protein 0.002 0.016 0.0458
Trypanosoma cruzi FHA domain containing protein, putative 0.001 0.0035 0.0205
Echinococcus multilocularis copper transporting ATPase 1 0.0008 0.0018 0.0018
Trichomonas vaginalis set domain proteins, putative 0.0086 0.0988 0.2319
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0139 0.1649 0.471
Echinococcus multilocularis lamin 0.0023 0.0203 0.0203
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0009 0.0023 0.0067
Echinococcus multilocularis lamin dm0 0.0023 0.0203 0.0203
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0201 0.0201
Brugia malayi SWIRM domain containing protein 0.002 0.016 0.0458
Brugia malayi Ets-domain containing protein 0.0072 0.0817 0.2332
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0047 0.0133
Giardia lamblia Beta tubulin 0.0032 0.0317 0.0705
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0008 0.0018 0.0042
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0099
Schistosoma mansoni tubulin subunit beta 0.0032 0.0317 0.0437
Schistosoma mansoni alpha tubulin 0.0032 0.0317 0.0437
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0065 0.0384
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0047 0.0133
Brugia malayi Tubulin beta chain 0.0018 0.0143 0.0408
Trypanosoma brucei epsilon tubulin 0.0032 0.0317 0.1863
Echinococcus multilocularis zinc finger protein 0.002 0.0164 0.0164
Chlamydia trachomatis DNA ligase 0.001 0.0035 0.0248
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0047 0.0064
Trichomonas vaginalis tubulin beta chain, putative 0.0032 0.0317 0.0745
Trypanosoma cruzi tubulin delta chain 0.0014 0.009 0.053
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Trichomonas vaginalis aldo/keto reductase, putative 0.0066 0.0734 0.1722
Echinococcus granulosus survival motor neuron protein 1 0.0288 0.3501 0.4825
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0009 0.0023 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0202 0.0597
Trichomonas vaginalis maltase-glucoamylase, putative 0.0031 0.0301 0.0706
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0671 0.0925
Echinococcus granulosus ecdysone induced protein 78C 0.0009 0.0023 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0009 0.0023 0.0067
Schistosoma mansoni lamin 0.0023 0.0203 0.028
Leishmania major hypothetical protein, conserved 0.0035 0.0357 0.2096
Schistosoma mansoni hypothetical protein 0.0021 0.0177 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0035 0.0082
Echinococcus granulosus lamin dm0 0.0023 0.0203 0.028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0143 0.0408
Trypanosoma brucei alpha tubulin 0.0032 0.0317 0.1863
Giardia lamblia DINP protein human, muc B family 0.0039 0.0398 0.0895
Brugia malayi hypothetical protein 0.0288 0.3501 1
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0065 0.0384
Echinococcus multilocularis tubulin alpha 0.0032 0.0317 0.0317
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0051 0.0119
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0008 0.0018 0.0042
Entamoeba histolytica aldose reductase, putative 0.0066 0.0734 0.1722
Echinococcus granulosus polyadenylate binding protein 0.0007 0.0008 0.0011
Loa Loa (eye worm) alpha-tubulin 0.0032 0.0317 0.0906
Trypanosoma brucei glucosidase, putative 0.0031 0.0301 0.1765
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0012 0.0059 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0248 0.1457
Loa Loa (eye worm) hypothetical protein 0.0035 0.0357 0.1019
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0073 0.0819 0.5925
Trichomonas vaginalis tubulin, putative 0.0032 0.0317 0.0745
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0011 0.0049 0.0068
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0008 0.001 0.0023
Schistosoma mansoni ets-related 0.0011 0.0047 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0009 0.0023 0.0067
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0066 0.0734 0.1722
Schistosoma mansoni alpha glucosidase 0.0031 0.0301 0.0414
Loa Loa (eye worm) hypothetical protein 0.002 0.016 0.0458
Schistosoma mansoni lamin 0.0023 0.0203 0.028
Echinococcus granulosus tubulin alpha 0.0032 0.0317 0.0437
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0102 0.118 0.6929
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0035 0.0205
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0065 0.009
Leishmania major hypothetical protein, conserved 0.0043 0.0451 0.2649
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0065 0.0384
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0099
Loa Loa (eye worm) hypothetical protein 0.0014 0.009 0.0258
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.013 0.0384
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0202 0.1188
Brugia malayi E1-E2 ATPase family protein 0.0008 0.0018 0.0051
Schistosoma mansoni topbp1 0.001 0.0035 0.0048
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0398 0.2335
Echinococcus granulosus tubulin epsilon chain 0.0032 0.0317 0.0437
Leishmania major P-type H -ATPase, putative 0.0008 0.0018 0.0106
Echinococcus granulosus neutral alpha glucosidase AB 0.0031 0.0301 0.0414
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0035 0.0205
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0051 0.0119
Schistosoma mansoni RAR-like nuclear receptor 0.0009 0.0023 0.0032
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0451 0.0621
Onchocerca volvulus 0.0051 0.0548 0.3969
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0201 0.0277
Trichomonas vaginalis tubulin beta chain, putative 0.0032 0.0317 0.0745
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0014 0.009 0.053
Plasmodium falciparum tubulin epsilon chain, putative 0.0032 0.0317 0.1863
Onchocerca volvulus 0.0086 0.0988 0.7147
Loa Loa (eye worm) hypothetical protein 0.0041 0.0431 0.1232
Echinococcus multilocularis tubulin alpha chain 0.0032 0.0317 0.0317
Echinococcus multilocularis peroxisome assembly protein 26 0.0032 0.0317 0.0317
Trypanosoma cruzi cation-transporting ATPase, putative 0.0008 0.0018 0.0106
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Brugia malayi nuclear receptor NHR-88 0.0009 0.0023 0.0067
Loa Loa (eye worm) hypothetical protein 0.002 0.016 0.0458
Toxoplasma gondii aldose reductase, putative 0.0066 0.0734 0.4309
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0066 0.0734 0.36
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0019 0.0153 0.0897
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0008 0.0018 0.0018
Plasmodium vivax tubulin alpha chain, putative 0.0032 0.0317 0.1863
Brugia malayi Pre-SET motif family protein 0.0011 0.0051 0.0146
Trichomonas vaginalis glutaminase, putative 0.0222 0.2676 0.6284
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0009 0.0023 0.0067
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0054 0.0075
Mycobacterium ulcerans DNA gyrase subunit B 0.0063 0.0695 0.2053
Loa Loa (eye worm) oxidoreductase 0.0066 0.0734 0.2095
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0047 0.0064
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0051 0.007
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0102 0.118 0.6929
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0023 0.0032
Leishmania major p-glycoprotein 0.0011 0.0051 0.0297
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.016 0.0221
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0398 0.2335
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0008 0.0018 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0357 0.2096
Toxoplasma gondii kringle domain-containing protein 0.0035 0.0357 0.2096
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0202 0.0606
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0035 0.0357 0.2096
Schistosoma mansoni multidrug resistance protein 0.0011 0.0051 0.007
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.016 0.0481
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0118 0.0354
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0066 0.0734 0.4309
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0008 0.0018 0.0051
Brugia malayi latrophilin 2 splice variant baaae 0.0029 0.0278 0.0795
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0019 0.0153 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0426 0.1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0076 0.0858 0.2449
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0023 0.0067
Schistosoma mansoni hypothetical protein 0.0013 0.0084 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0065 0.0384
Loa Loa (eye worm) fli-1 protein 0.022 0.265 0.7569
Loa Loa (eye worm) hypothetical protein 0.0073 0.082 0.2342
Loa Loa (eye worm) DNA topoisomerase I 0.0144 0.1702 0.4862
Echinococcus multilocularis tissue type plasminogen activator 0.0035 0.0357 0.0357
Brugia malayi Intermediate filament tail domain containing protein 0.0023 0.0203 0.0579
Echinococcus multilocularis protein dispatched 1 0.0047 0.0498 0.0498
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0177 0.0505
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0008 0.0018 0.0018
Echinococcus multilocularis FTZ F1 alpha 0.0009 0.0023 0.0023
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0202 0.0597
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0008 0.0018 0.0051
Echinococcus granulosus DNA topoisomerase 1 0.0144 0.1702 0.2346
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0023 0.0067
Loa Loa (eye worm) beta-tubulin 0.0032 0.0317 0.0906
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0035 0.0082
Trichomonas vaginalis cation-transporting ATPase, putative 0.0008 0.0018 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0065 0.0384
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.009 0.0212
Brugia malayi beta-lactamase family protein 0.0043 0.0451 0.1288
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0063 0.0695 0.2084
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0451 0.1059
Schistosoma mansoni tubulin subunit epsilon 0.0032 0.0317 0.0437
Echinococcus multilocularis phosphoserine phosphatase 0.0008 0.0018 0.0018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0023 0.0067
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0033 0.0323 0.1895
Toxoplasma gondii histone lysine-specific demethylase 0.002 0.016 0.0941
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0009 0.0023 0.0067
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0451 0.0621
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0009 0.0023 0.0032
Echinococcus multilocularis hypothetical protein 0.0032 0.0317 0.0317
Echinococcus granulosus tubulin beta 1 chain 0.0032 0.0317 0.0437
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.0153 0.0359
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0323 0.1895
Leishmania major epsilon tubulin, putative 0.0032 0.0317 0.1863
Trypanosoma cruzi DNA polymerase eta, putative 0.0059 0.0655 0.3846
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0398 0.1193
Schistosoma mansoni multidrug resistance protein 0.0011 0.0051 0.007
Schistosoma mansoni polyadenylate binding protein 0.0007 0.0008 0.0011
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Brugia malayi beta-tubulin, identical 0.0032 0.0317 0.0906
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0066 0.0734 0.2095
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0051 0.0119
Trypanosoma brucei tubulin gamma chain 0.0032 0.0317 0.1863
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0035 0.0099
Loa Loa (eye worm) latrophilin receptor protein 2 0.0013 0.0084 0.0239
Onchocerca volvulus Cirhin homolog 0.0118 0.1382 1
Brugia malayi intermediate filament protein 0.0023 0.0203 0.0579
Echinococcus multilocularis thyroid hormone receptor alpha 0.0009 0.0023 0.0023
Onchocerca volvulus 0.0011 0.0051 0.0369
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0065 0.0384
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0153 0.0359
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0051 0.0119
Echinococcus multilocularis aldehyde reductase 0.0047 0.0497 0.0497
Leishmania major glycosyl hydrolase-like protein 0.0012 0.0059 0.0348
Echinococcus multilocularis multidrug resistance protein 1 0.0008 0.001 0.001
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0051 0.0119
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0066 0.0734 0.4309
Entamoeba histolytica P-glyco protein 6, putative 0.0011 0.0051 0.0119
Trypanosoma cruzi epsilon tubulin, putative 0.0032 0.0317 0.1863
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0144 0.1702 1
Trypanosoma cruzi zeta tubulin, putative 0.0014 0.009 0.053
Leishmania major alpha glucosidase II subunit, putative 0.0031 0.0301 0.1765
Schistosoma mansoni amine oxidase 0.002 0.016 0.0221
Entamoeba histolytica P-glycoprotein 5, putative 0.0011 0.0051 0.0119
Loa Loa (eye worm) HMG box family protein 0.0058 0.0633 0.1809
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0009 0.0023 0.017
Loa Loa (eye worm) hypothetical protein 0.005 0.0541 0.1545
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0201 0.0277
Toxoplasma gondii P-type ATPase PMA1 0.0008 0.0018 0.0106
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Echinococcus granulosus tubulin alpha chain 0.0032 0.0317 0.0437
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0451 0.1059
Brugia malayi amine oxidase, flavin-containing family protein 0.002 0.016 0.0458
Loa Loa (eye worm) hypothetical protein 0.0017 0.013 0.0371
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0099
Brugia malayi DKFZp564C0469 protein 0.001 0.0035 0.0099
Plasmodium vivax hypothetical protein, conserved 0.002 0.016 0.0941
Schistosoma mansoni gabp alpha 0.0072 0.0817 0.1125
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0426 0.1217
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Plasmodium falciparum alpha tubulin 2 0.0032 0.0317 0.1863
Echinococcus multilocularis lysine specific histone demethylase 1A 0.002 0.016 0.016
Schistosoma mansoni cation-transporting atpase worm 0.0008 0.0018 0.0025
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0451 0.1353
Trypanosoma brucei ISWI complex protein 0.0016 0.0109 0.0643
Echinococcus granulosus protein C ets 2 0.0011 0.0047 0.0064
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0008 0.0018 0.0025
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0.007 0.0199
Trypanosoma cruzi epsilon tubulin, putative 0.0032 0.0317 0.1863
Toxoplasma gondii P-type ATPase4, putative 0.0008 0.0018 0.0106
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0008 0.0018 0.0106
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0301 0.0706
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0013 0.0084 0.0239
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0008 0.0018 0.0053
Loa Loa (eye worm) hypothetical protein 0.0066 0.0734 0.2095
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0051 0.0119
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.1105 0.2594
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0301 0.0706
Loa Loa (eye worm) oxidoreductase 0.0066 0.0734 0.2095
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0013 0.0084 0.0115
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0032 0.0317 0.0317
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0051 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4259 1
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0035 0.0205
Echinococcus multilocularis ecdysone induced protein 78C 0.0009 0.0023 0.0023
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0655 0.187
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0011 0.0051 0.0151
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0067
Plasmodium vivax hypothetical protein, conserved 0.002 0.016 0.0941
Trichomonas vaginalis sucrase-isomaltase, putative 0.0031 0.0301 0.0706
Trypanosoma brucei beta tubulin 0.0032 0.0317 0.1863
Loa Loa (eye worm) hypothetical protein 0.0043 0.0446 0.1275
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0051 0.0051
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0118 0.0354
Loa Loa (eye worm) hypothetical protein 0.0015 0.01 0.0284
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0171 0.2037 0.6111
Loa Loa (eye worm) hypothetical protein 0.0043 0.0451 0.1288
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0035 0.0035
Onchocerca volvulus 0.0059 0.0647 0.4684
Schistosoma mansoni hypothetical protein 0.004 0.0408 0.0562
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Echinococcus multilocularis Tubulin alpha 1 chain 0.0032 0.0317 0.0317
Entamoeba histolytica P-glycoprotein-2, putative 0.0011 0.0051 0.0119
Brugia malayi Tubulin alpha chain 0.0014 0.009 0.0258
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Echinococcus granulosus tubulin gamma 1 chain 0.0032 0.0317 0.0437
Loa Loa (eye worm) alpha-tubulin 0.0032 0.0317 0.0906
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0065 0.0384
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0023 0.0203 0.0579
Echinococcus multilocularis protein patched 0.0041 0.0426 0.0426
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Trypanosoma brucei P-type H+-ATPase, putative 0.0008 0.0018 0.0106
Loa Loa (eye worm) hypothetical protein 0.002 0.016 0.0458
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0451 0.1353
Loa Loa (eye worm) hypothetical protein 0.0039 0.0401 0.1146
Loa Loa (eye worm) hypothetical protein 0.0012 0.0059 0.0169
Brugia malayi Nuclear hormone receptor-like 1 0.0009 0.0023 0.0067
Mycobacterium leprae cell division protein FtsZ 0.0014 0.009 0.0443
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0059 0.0139
Echinococcus multilocularis tubulin alpha chain 0.0032 0.0317 0.0317
Schistosoma mansoni tubulin subunit beta 0.0032 0.0317 0.0437
Echinococcus multilocularis aldo keto reductase 0.0066 0.0734 0.0734
Schistosoma mansoni tubulin subunit alpha 0.0032 0.0317 0.0437
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0451 0.1353
Leishmania major DNA topoisomerase IB, large subunit 0.0144 0.1702 1
Loa Loa (eye worm) glutaminase 2 0.0222 0.2676 0.7643
Echinococcus granulosus expressed conserved protein 0.009 0.1032 0.1423
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0132 0.0181
Brugia malayi Pre-SET motif family protein 0.0076 0.0858 0.2449
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0035 0.0082
Leishmania major zeta tubulin, putative 0.0014 0.009 0.053
Schistosoma mansoni hypothetical protein 0.0011 0.0047 0.0064
Entamoeba histolytica tubulin family protein 0.0032 0.0317 0.0745
Schistosoma mansoni hypothetical protein 0.0016 0.0109 0.0151
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0008 0.0018 0.0042
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0371 0.0371
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0.0051 0.0119
Trypanosoma cruzi UDP-galactopyranose mutase 0.002 0.016 0.0941
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0008 0.0018 0.0106
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0398 0.0934
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Schistosoma mansoni alpha-glucosidase 0.012 0.1408 0.194
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0398 0.0548
Schistosoma mansoni DNA topoisomerase type I 0.0144 0.1702 0.2346
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0008 0.0018 0.0025
Loa Loa (eye worm) hypothetical protein 0.0044 0.0459 0.1312
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0008 0.0018 0.0042
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0451 0.2649
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0202 0.0597
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Echinococcus granulosus aldo keto reductase 0.0066 0.0734 0.1011
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0014 0.009 0.0838
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0202 0.0475
Chlamydia trachomatis DNA gyrase subunit A 0.0023 0.0203 0.2737
Loa Loa (eye worm) hypothetical protein 0.002 0.016 0.0458
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4259 1
Brugia malayi DNA topoisomerase I 0.0144 0.1702 0.4862
Loa Loa (eye worm) hypothetical protein 0.0096 0.1105 0.3155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4259 1
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0008 0.0018 0.0054
Echinococcus multilocularis protein pangolin J 0.0058 0.0633 0.0633
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0009 0.0023 0.0032
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0451 0.1288
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0398 0.0548
Schistosoma mansoni hypothetical protein 0.004 0.0408 0.0562
Echinococcus multilocularis polyadenylate binding protein 0.0007 0.0008 0.0008
Giardia lamblia DNA topoisomerase II 0.0102 0.1182 0.2745
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0009 0.0023 0.0032
Loa Loa (eye worm) BEN-1 protein 0.0032 0.0317 0.0906
Leishmania major poly(A)-binding protein 2 0.0007 0.0008 0.0046
Giardia lamblia Alpha-tubulin 0.0032 0.0317 0.0705
Echinococcus granulosus copper transporting ATPase 1 0.0008 0.0018 0.0025
Echinococcus granulosus aldo keto reductase 0.0066 0.0734 0.1011
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0008 0.0018 0.0054
Loa Loa (eye worm) E1-E2 ATPase 0.0008 0.0018 0.0051
Brugia malayi Tubulin alpha-2 chain 0.0032 0.0317 0.0906
Schistosoma mansoni pol-related 0.0066 0.0734 0.1011
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.016 0.0941
Loa Loa (eye worm) hypothetical protein 0.0011 0.0054 0.0155
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0043 0.0446 0.1275
Leishmania major aldo-keto reductase-like protein 0.0066 0.0734 0.4309
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0118 0.0354
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0008 0.0018 0.0042
Trypanosoma cruzi proton motive ATPase 1, putative 0.0008 0.0018 0.0106
Echinococcus multilocularis beta tubulin 0.0032 0.0317 0.0317
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0065 0.0384
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0099
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0349 0.4259 1
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0023 0.0032
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0013 0.0084 0.0084
Echinococcus multilocularis Eukaryotic translation initiation factor 4H 0.0109 0.1277 0.1277
Schistosoma mansoni DNA topoisomerase II 0.0107 0.1252 0.1725
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0023 0.0067
Trypanosoma cruzi tubulin gamma chain 0.0032 0.0317 0.1863
Schistosoma mansoni type V p-type atpase isoform 0.0008 0.0018 0.0025
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0398 0.0398
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.1105 0.1522
Schistosoma mansoni hypothetical protein 0.021 0.2529 0.3485
Brugia malayi beta-lactamase family protein 0.0043 0.0451 0.1288
Loa Loa (eye worm) hypothetical protein 0.0017 0.013 0.0371
Brugia malayi photoreceptor-specific nuclear receptor 0.0009 0.0023 0.0067
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0063 0.0695 1
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0451 0.2213
Echinococcus multilocularis tubulin epsilon chain 0.0032 0.0317 0.0317
Onchocerca volvulus 0.0023 0.0203 0.1468
Echinococcus multilocularis tyrosine protein kinase shark 0.008 0.0906 0.0906
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0008 0.0018 0.0053
Loa Loa (eye worm) tubulin beta-2A chain 0.0032 0.0317 0.0906
Schistosoma mansoni hypothetical protein 0.0013 0.0084 0.0115
Toxoplasma gondii DNA topoisomerase I, putative 0.0144 0.1702 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0011 0.0051 0.0297
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0051
Echinococcus granulosus beta catenin 0.0119 0.1392 0.1918
Loa Loa (eye worm) tubulin beta-1 chain 0.0032 0.0317 0.0906
Loa Loa (eye worm) hypothetical protein 0.0011 0.0051 0.0144
Leishmania major hypothetical protein, conserved 0.0016 0.0109 0.0643
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0398 0.1136
Plasmodium falciparum aldo-keto reductase, putative 0.0019 0.0153 0.0897
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0398 0.1175
Entamoeba histolytica hypothetical protein 0.0071 0.0798 0.1873
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0051 0.0051
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0279 0.3384 1
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0008 0.0018 0.0106
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0059 0.0139
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0051 0.0119
Schistosoma mansoni zinc finger protein 0.0016 0.0109 0.0151
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0451 0.1353
Schistosoma mansoni hypothetical protein 0.0059 0.0647 0.0892
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0008 0.0018 0.0042
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0051 0.007
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0047 0.0064
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0008 0.0018 0.0042
Echinococcus multilocularis 0.002 0.016 0.016
Treponema pallidum DNA ligase (lig) 0.001 0.0035 0.004
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0008 0.0018 0.0053
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0012 0.0059 0.0348
Schistosoma mansoni tubulin subunit delta 0.0014 0.009 0.0124
Echinococcus multilocularis phosphoserine phosphatase 0.0008 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0043 0.0451 0.1288
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0202 0.0577
Loa Loa (eye worm) hypothetical protein 0.002 0.016 0.0458
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0054 0.0054
Echinococcus multilocularis aldo keto reductase 0.0066 0.0734 0.0734
Loa Loa (eye worm) hypothetical protein 0.0015 0.01 0.0284
Treponema pallidum fructose-bisphosphate aldolase 0.0349 0.4259 1
Brugia malayi HMG box family protein 0.0058 0.0633 0.1809
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0065 0.0384
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0008 0.0018 0.0054
Echinococcus granulosus neuropeptide receptor A26 0.0396 0.4835 0.6663
Toxoplasma gondii beta-tubulin, putative 0.0032 0.0317 0.1863
Echinococcus granulosus Tubulin beta 2C chain 0.0032 0.0317 0.0437
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0398 0.0934
Echinococcus granulosus Tubulin alpha 1 chain 0.0032 0.0317 0.0437
Brugia malayi hypothetical protein 0.0071 0.0798 0.2278
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0065 0.0384
Leishmania major delta tubulin, putative 0.0014 0.009 0.053
Entamoeba histolytica tubulin gamma chain 0.0032 0.0317 0.0745
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0023 0.0023
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.0153 0.0359
Onchocerca volvulus 0.0023 0.0202 0.1463
Brugia malayi transcription factor E74 isoform 0.0011 0.0047 0.0133
Echinococcus multilocularis protoporphyrinogen oxidase 0.002 0.016 0.016
Leishmania major poly(A)-binding protein 3 0.0007 0.0008 0.0046
Schistosoma mansoni DNA ligase IV 0.001 0.0035 0.0048
Giardia lamblia Replication factor C, subunit 1 0.001 0.0035 0.004
Entamoeba histolytica hypothetical protein 0.001 0.0035 0.0082
Echinococcus multilocularis Tubulin alpha 1 chain 0.0032 0.0317 0.0317
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Loa Loa (eye worm) hypothetical protein 0.0023 0.0203 0.0579
Brugia malayi Bromodomain containing protein 0.0039 0.04 0.1144
Echinococcus granulosus tubulin alpha chain 0.0032 0.0317 0.0437
Echinococcus granulosus hypothetical protein 0.0066 0.0734 0.1011
Giardia lamblia Beta tubulin 0.0032 0.0317 0.0705
Loa Loa (eye worm) multidrug resistance protein 3 0.0011 0.0051 0.0144
Trypanosoma brucei aldo-keto reductase, putative 0.0066 0.0734 0.4309
Echinococcus granulosus Tubulin alpha 1 chain 0.0032 0.0317 0.0437
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0008 0.0018 0.0042
Brugia malayi Armadillo/beta-catenin-like repeat family protein 0.0119 0.1392 0.3974
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0059 0.0139
Echinococcus multilocularis survival motor neuron protein 1 0.0288 0.3501 0.3501
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0014 0.009 0.0212
Schistosoma mansoni hypothetical protein 0.004 0.0408 0.0562
Echinococcus granulosus aldehyde reductase 0.0047 0.0497 0.0685
Schistosoma mansoni beta-catenin 0.0119 0.1392 0.1918
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0139 0.0398
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0451 0.1059
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0011 0.0051 0.007
Onchocerca volvulus 0.0081 0.0918 0.6646
Schistosoma mansoni survival motor neuron protein 0.0059 0.0647 0.0892
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0008 0.0018 0.0042
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Mycobacterium ulcerans DNA gyrase subunit A 0.0023 0.0203 0.0601
Brugia malayi ecdysteroid receptor 0.0009 0.0023 0.0067
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0019 0.0153 0.0897
Trypanosoma cruzi copper-transporting ATPase, putative 0.0008 0.0018 0.0106
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Leishmania major proton motive ATPase, putative 0.0008 0.0018 0.0106
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0398 0.1136
Trichomonas vaginalis cation-transporting ATPase, putative 0.0008 0.0018 0.0042
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0051 0.0051
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0035 0.0205
Onchocerca volvulus 0.0066 0.0734 0.5309
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0047 0.0047
Trypanosoma brucei aldo/keto reductase, putative 0.0019 0.0153 0.0897
Giardia lamblia Aldose reductase 0.0066 0.0734 0.1687
Mycobacterium ulcerans oxidoreductase 0.002 0.016 0.0473
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0035 0.0082
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.0109 0.1277 0.176
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0734 0.1011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.001 0.0046 0.0063
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.1123 0.1547
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0028 0.0263 0.1291
Echinococcus multilocularis T cell transcription factor 4 long C terminal 0.0058 0.0633 0.0633
Trichomonas vaginalis tubulin gamma chain, putative 0.0032 0.0317 0.0745
Loa Loa (eye worm) hypothetical protein 0.0073 0.082 0.2342
Trichomonas vaginalis abcb9, putative 0.0011 0.0051 0.0119
Brugia malayi PHD-finger family protein 0.0025 0.0231 0.066
Loa Loa (eye worm) hypothetical protein 0.0043 0.0451 0.1288
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0047 0.0047
Leishmania major UDP-galactopyranose mutase 0.002 0.016 0.0941
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.002 0.016 0.0941
Trichomonas vaginalis tubulin beta chain, putative 0.0032 0.0317 0.0745
Echinococcus granulosus Tubulin beta 2C chain 0.0032 0.0317 0.0437
Echinococcus granulosus Tubulin beta 2C chain 0.0032 0.0317 0.0437
Mycobacterium ulcerans protoporphyrinogen oxidase 0.002 0.016 0.0473
Loa Loa (eye worm) hypothetical protein 0.0017 0.013 0.0371
Trypanosoma cruzi P-type H+-ATPase, putative 0.0008 0.0018 0.0106
Echinococcus granulosus tubulin alpha 1C chain 0.0032 0.0317 0.0437
Plasmodium falciparum DNA gyrase subunit A 0.0023 0.0203 0.1194
Loa Loa (eye worm) hypothetical protein 0.0029 0.0278 0.0795
Trypanosoma brucei prostaglandin f synthase 0.0066 0.0734 0.4309
Giardia lamblia Beta tubulin 0.0032 0.0317 0.0705
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0008 0.0018 0.0042
Mycobacterium tuberculosis Conserved protein 0.0043 0.0451 0.1353
Trypanosoma brucei unspecified product 0.0027 0.0248 0.1457
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0451 0.2649
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0011 0.0051 0.03
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0009 0.0023 0.0032
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.002 0.016 0.0786
Echinococcus multilocularis voltage gated potassium channel subunit 0.0019 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0051
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0398 0.0934
Plasmodium vivax aldehyde reductase, putative 0.0019 0.0153 0.0897
Trichomonas vaginalis tubulin alpha chain, putative 0.0018 0.0143 0.0336
Schistosoma mansoni glutaminase 0.0222 0.2676 0.3688
Schistosoma mansoni pangolin 0.0058 0.0633 0.0873
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0035 0.0082
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0008 0.0018 0.0042
Mycobacterium ulcerans oxidoreductase 0.0066 0.0734 0.2167
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0066 0.0734 0.2095
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0398 0.2335
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0008 0.0018 0.0106
Brugia malayi Tubulin alpha-2 chain 0.0032 0.0317 0.0906
Plasmodium falciparum tubulin delta chain, putative 0.0014 0.009 0.053
Plasmodium falciparum polyadenylate-binding protein, putative 0.0007 0.0008 0.0046
Schistosoma mansoni atpase class VI type 11c 0.0008 0.0018 0.0025
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0301 0.0706
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Trichomonas vaginalis tubulin, putative 0.0014 0.009 0.0212
Schistosoma mansoni tubulin subunit gamma 0.0032 0.0317 0.0437
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0009 0.0023 0.0067
Brugia malayi CHE-14 protein 0.0041 0.0426 0.1217
Schistosoma mansoni tubulin subunit alpha 0.0032 0.0317 0.0437
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0047 0.0133
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0067
Loa Loa (eye worm) hypothetical protein 0.0013 0.0084 0.0239
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0047 0.0047
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0008 0.0018 0.0106
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0073 0.0819 0.5925
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0047 0.0133
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0008 0.0018 0.0106
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0008 0.0018 0.0088
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0301 0.0706
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Onchocerca volvulus 0.0019 0.0153 0.1106
Onchocerca volvulus 0.0043 0.0451 0.3264
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0012 0.0059 0.0139
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0202 0.0475
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0734 0.1011
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0279 0.3384 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.1105 0.1105
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Echinococcus multilocularis nibrin 0.001 0.0035 0.0035
Toxoplasma gondii ABC1 family protein 0.0043 0.0451 0.2649
Echinococcus granulosus alpha tubulin 0.0032 0.0317 0.0437
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0398 0.1175
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.013 0.0389
Brugia malayi Na,K-ATPase alpha subunit 0.0008 0.0018 0.0051
Schistosoma mansoni cation-transporting atpase worm 0.0008 0.0018 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0065 0.0384
Echinococcus multilocularis Tubulin beta 2C chain 0.0032 0.0317 0.0317
Loa Loa (eye worm) beta-lactamase 0.0043 0.0451 0.1288
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0023 0.0067
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0301 0.0706
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0035 0.0082
Schistosoma mansoni smdr2 0.0011 0.0051 0.007
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.013 0.0763
Mycobacterium ulcerans lipase LipD 0.0043 0.0451 0.1332
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Plasmodium falciparum alpha tubulin 1 0.0032 0.0317 0.1863
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0301 0.0706
Trichomonas vaginalis tubulin epsilon chain, putative 0.0032 0.0317 0.0745
Trichomonas vaginalis taga, putative 0.0011 0.0051 0.0119
Leishmania major gamma-tubulin 0.0032 0.0317 0.1863
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0008 0.0018 0.0106
Trypanosoma brucei tubulin delta chain 0.0014 0.009 0.053
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0008 0.0018 0.0042
Toxoplasma gondii alpha-tubulin I, putative 0.0032 0.0317 0.1863
Loa Loa (eye worm) glutaminase 0.0222 0.2676 0.7643
Loa Loa (eye worm) oxidoreductase 0.0066 0.0734 0.2095
Echinococcus multilocularis microtubule associated protein 2 0.059 0.7257 0.7257
Trichomonas vaginalis tubulin gamma chain, putative 0.0014 0.009 0.0212
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0047 0.0047
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.1615 0.2225
Schistosoma mansoni DNA topoisomerase type I 0.0144 0.1702 0.2346
Mycobacterium tuberculosis Conserved protein 0.0043 0.0451 0.1353
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0009 0.0023 0.0067
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0451 0.1059
Brugia malayi hypothetical protein 0.001 0.0035 0.0099
Onchocerca volvulus 0.0066 0.0734 0.5309
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0008 0.0018 0.0106
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0121 0.1415 0.8313
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Schistosoma mansoni phosphoserine phosphatase 0.0008 0.0018 0.0025
Giardia lamblia Fructose-bisphosphate aldolase 0.0349 0.4259 1
Trypanosoma cruzi aldo/keto reductase, putative 0.0019 0.0153 0.0897
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0301 0.0706
Onchocerca volvulus 0.0011 0.0051 0.0365
Brugia malayi Tubulin alpha chain 0.0032 0.0317 0.0906
Trypanosoma brucei alpha tubulin 0.0032 0.0317 0.1863
Toxoplasma gondii beta-1 tubulin, putative 0.0032 0.0317 0.1863
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.013 0.1652
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0009 0.0023 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0009 0.0023 0.0067
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0371 0.0511
Toxoplasma gondii beta tubulin 0.0032 0.0317 0.1863
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0023 0.0067
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0051 0.0119
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0051 0.0119
Echinococcus granulosus tubulin alpha 3 chain 0.0032 0.0317 0.0437
Brugia malayi Calcitonin receptor-like protein seb-1 0.0043 0.0446 0.1275
Toxoplasma gondii cation-transporting atpase family protein 0.0008 0.0018 0.0106
Brugia malayi Tubulin beta chain 0.0014 0.009 0.0258
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0009 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0051
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0051 0.0051
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.002 0.016 0.0941
Echinococcus multilocularis neutral alpha glucosidase AB 0.0031 0.0301 0.0301
Trichomonas vaginalis tubulin beta chain, putative 0.0032 0.0317 0.0745
Schistosoma mansoni ATPase 0.0008 0.0018 0.0025
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0451 0.1353
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0011 0.0051 0.048
Echinococcus multilocularis neuropeptide receptor A26 0.0396 0.4835 0.4835
Trypanosoma brucei alpha tubulin, putative 0.0018 0.0143 0.084
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0065 0.0384
Trichomonas vaginalis tubulin epsilon chain, putative 0.0032 0.0317 0.0745
Onchocerca volvulus 0.0066 0.0734 0.5309
Trichomonas vaginalis tubulin beta chain, putative 0.0032 0.0317 0.0745
Trypanosoma brucei epsilon tubulin 0.0032 0.0317 0.1863
Mycobacterium tuberculosis Cell division protein FtsZ 0.0014 0.009 0.027
Loa Loa (eye worm) hypothetical protein 0.0043 0.0455 0.1301
Trypanosoma cruzi DNA topoisomerase II, putative 0.0102 0.118 0.6929
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0011 0.0051 0.0297
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0031 0.0301 0.0858
Plasmodium vivax protoporphyrinogen oxidase, putative 0.002 0.016 0.0941
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0066 0.0734 0.1722
Echinococcus multilocularis DNA topoisomerase 1 0.0144 0.1702 0.1702
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0398 0.0548
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0018 0.0143 0.0336
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0009 0.0023 0.0032
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.1615 0.1615
Giardia lamblia Epsilon tubulin 0.0014 0.009 0.017
Schistosoma mansoni aldo-keto reductase 0.0066 0.0734 0.1011
Schistosoma mansoni amine oxidase 0.002 0.016 0.0221
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0051 0.0051
Echinococcus granulosus tubulin subunit TubB 0.0032 0.0317 0.0437
Echinococcus multilocularis tubulin alpha chain 0.0032 0.0317 0.0317
Brugia malayi Steroid receptor seven-up type 2 0.0009 0.0023 0.0067
Plasmodium falciparum DNA gyrase subunit B 0.0063 0.0695 0.4082
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0059 0.0139
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0009 0.0023 0.0067
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0032 0.0317 0.1863
Entamoeba histolytica alcohol dehydrogenase, putative 0.0019 0.0153 0.0359
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0301 0.1765
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0099
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0012 0.0059 0.0139
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0734 0.1011
Schistosoma mansoni polyadenylate binding protein 0.0007 0.0008 0.0011
Entamoeba histolytica tubulin alpha-1 chain 0.0032 0.0317 0.0745
Trichomonas vaginalis cation-transporting ATPase, putative 0.0008 0.0018 0.0042
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0035 0.0099
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.001 0.0035 0.0171
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0734 0.1011
Plasmodium vivax delta tubulin, putative 0.0014 0.009 0.053
Plasmodium vivax tubulin alpha chain, putative 0.0032 0.0317 0.1863
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0107 0.1252 0.1725
Toxoplasma gondii aldo-keto reductase 0.0019 0.0153 0.0897
Trypanosoma brucei DNA polymerase eta, putative 0.0059 0.0655 0.3846
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0426 0.0587
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0063 0.0695 0.4082
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0798 0.1099
Loa Loa (eye worm) hypothetical protein 0.0121 0.1424 0.4068
Toxoplasma gondii alpha tubulin TUBA1 0.0032 0.0317 0.1863
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0008 0.0018 0.0018
Echinococcus granulosus replication factor c subunit 1 0.001 0.0035 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0009 0.0023 0.0067
Echinococcus granulosus tissue type plasminogen activator 0.0035 0.0357 0.0492
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0051 0.0119
Loa Loa (eye worm) hypothetical protein 0.0017 0.013 0.0371
Trichomonas vaginalis tubulin alpha chain, putative 0.0032 0.0317 0.0745
Echinococcus granulosus Tubulin alpha 1 chain 0.0032 0.0317 0.0437
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Trichomonas vaginalis aldo/keto reductase, putative 0.0066 0.0734 0.1722
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0734 0.1011
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0107 0.1252 0.1252
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Echinococcus granulosus Tubulin beta 2C chain 0.0032 0.0317 0.0437
Giardia lamblia Delta tubulin 0.0014 0.009 0.017
Brugia malayi tubulin alpha chain - mouse 0.0032 0.0317 0.0906
Loa Loa (eye worm) hypothetical protein 0.0023 0.0202 0.0577
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0451 0.1353
Plasmodium vivax calcium-transporting ATPase, putative 0.0008 0.0018 0.0106
Trichomonas vaginalis abcb9, putative 0.0011 0.0051 0.0119
Schistosoma mansoni copper ABC transporter ATPase 0.0008 0.0018 0.0025
Plasmodium falciparum tubulin beta chain 0.0032 0.0317 0.1863
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0067
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0019 0.0153 0.0897
Plasmodium vivax copper-transporting ATPase, putative 0.0008 0.0018 0.0106
Schistosoma mansoni tyrosine kinase 0.0078 0.0883 0.1217
Giardia lamblia DNA damage repair protein 0.0012 0.0065 0.0112
Echinococcus multilocularis phosphoserine phosphatase 0.0008 0.0018 0.0018
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0066 0.0734 0.2095
Echinococcus multilocularis aldo keto reductase 0.0066 0.0734 0.0734
Echinococcus multilocularis tubulin alpha chain 0.0032 0.0317 0.0317
Plasmodium vivax topoisomerase I, putative 0.0144 0.1702 1
Schistosoma mansoni alpha tubulin 0.0032 0.0317 0.0437
Trypanosoma brucei RNA helicase, putative 0.0072 0.0812 0.477
Echinococcus granulosus dna polymerase eta 0.0059 0.0655 0.0902
Plasmodium vivax DNA gyrase subunit B, putative 0.0063 0.0695 0.4082
Brugia malayi Ets-domain containing protein 0.0072 0.0817 0.2332
Echinococcus granulosus T cell transcription factor 4 long C terminal 0.0058 0.0633 0.0873
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0019 0.0153 0.0436
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0035 0.0082
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.1105 0.3155
Brugia malayi hypothetical protein 0.0008 0.0018 0.0051
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0202 0.1188
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0451 0.1332
Schistosoma mansoni tubulin subunit beta 0.0032 0.0317 0.0437
Echinococcus granulosus Tubulin beta 2C chain 0.0032 0.0317 0.0437
Brugia malayi multidrug resistance protein 3 0.0011 0.0051 0.0144
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0817 0.1125
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0008 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0011 0.0049 0.014
Loa Loa (eye worm) hypothetical protein 0.0023 0.0202 0.0577
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0014 0.009 0.0212
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0067
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Loa Loa (eye worm) hypothetical protein 0.0041 0.0426 0.1217
Plasmodium falciparum DNA topoisomerase 2 0.0107 0.1252 0.7353
Plasmodium falciparum topoisomerase I 0.0144 0.1702 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.016 0.0481
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0051 0.0548 0.1567
Echinococcus granulosus aldo keto reductase 0.0066 0.0734 0.1011
Loa Loa (eye worm) BEN-1 protein 0.0032 0.0317 0.0906
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0426 0.0426
Plasmodium falciparum replication factor C subunit 1, putative 0.001 0.0035 0.0205
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.002 0.016 0.0941
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Schistosoma mansoni retinoic acid receptor RXR 0.0009 0.0023 0.0032
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0202 0.0992
Echinococcus multilocularis tubulin gamma 1 chain 0.0032 0.0317 0.0317
Echinococcus multilocularis phosphoserine phosphatase 0.0008 0.0018 0.0018
Trichomonas vaginalis esterase, putative 0.0043 0.0451 0.1059
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Onchocerca volvulus 0.0043 0.0451 0.3264
Schistosoma mansoni steroid hormone receptor ad4bp 0.0009 0.0023 0.0032
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0248 0.1457
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0065 0.0384
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0008 0.0018 0.0051
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0202 0.0597
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0023 0.0203 0.2552
Mycobacterium tuberculosis Conserved protein 0.0019 0.0153 0.0458
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0451 0.1288
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0067
Loa Loa (eye worm) hypothetical protein 0.0017 0.013 0.0371
Brugia malayi Cell division protein ftsZ 0.0014 0.009 0.0258
Brugia malayi glutaminase DH11.1 0.0222 0.2676 0.7643
Trypanosoma cruzi P-type H+-ATPase, putative 0.0008 0.0018 0.0106
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0008 0.0018 0.0054
Trypanosoma cruzi zeta tubulin, putative 0.0014 0.009 0.053
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0043 0.0446 0.1275
Loa Loa (eye worm) tubulin alpha chain 0.0032 0.0317 0.0906
Echinococcus multilocularis tubulin beta 1 chain 0.0032 0.0317 0.0317
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0734 0.1011
Echinococcus multilocularis protein C ets 2 0.0011 0.0047 0.0047
Plasmodium falciparum copper-transporting ATPase 0.0008 0.0018 0.0106
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0202 0.0475
Plasmodium falciparum protoporphyrinogen oxidase 0.002 0.016 0.0941
Trypanosoma cruzi tubulin delta chain 0.0014 0.009 0.053
Trypanosoma brucei alpha tubulin 0.0032 0.0317 0.1863
Loa Loa (eye worm) hypothetical protein 0.0011 0.0049 0.014
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0023
Trichomonas vaginalis aldo/keto reductase, putative 0.0066 0.0734 0.1722
Loa Loa (eye worm) TOPoisomerase family member 0.0107 0.1252 0.3575
Mycobacterium tuberculosis Probable oxidoreductase 0.0066 0.0734 0.22
Loa Loa (eye worm) hypothetical protein 0.0086 0.098 0.2798
Loa Loa (eye worm) hypothetical protein 0.0011 0.0051 0.0144
Echinococcus multilocularis tubulin alpha 3 chain 0.0032 0.0317 0.0317
Trypanosoma cruzi DNA topoisomerase II, putative 0.0102 0.118 0.6929
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0132 0.0132
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0023 0.0032
Brugia malayi Fli-1 protein 0.022 0.265 0.7569
Brugia malayi Bromodomain containing protein 0.0076 0.0865 0.247
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0023 0.0032
Trichomonas vaginalis tubulin, putative 0.0018 0.0143 0.0336
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0047 0.0133
Plasmodium vivax tubulin epsilon chain, putative 0.0032 0.0317 0.1863
Schistosoma mansoni cation-transporting ATPase 0.0008 0.0018 0.0025
Loa Loa (eye worm) HMP-2 protein 0.0119 0.1392 0.3974
Brugia malayi Tubulin gamma chain 0.0032 0.0317 0.0906
Mycobacterium ulcerans hypothetical protein 0.0043 0.0451 0.1332
Plasmodium vivax cation transporting ATPase, putative 0.0008 0.0018 0.0106
Leishmania major DNA polymerase eta, putative 0.0059 0.0655 0.3846
Mycobacterium leprae Probable lipase LipE 0.0043 0.0451 0.2213
Echinococcus granulosus Eukaryotic translation initiation factor 4H 0.0109 0.1277 0.176
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0051 0.0119
Brugia malayi Kringle domain containing protein 0.0035 0.0357 0.1019
Echinococcus multilocularis tubulin delta chain 0.0014 0.009 0.009
Trichomonas vaginalis abcb9, putative 0.0011 0.0051 0.0119
Echinococcus multilocularis musashi 0.0023 0.0203 0.0203
Echinococcus granulosus dna polymerase kappa 0.0039 0.0398 0.0548
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0051 0.007
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0051 0.007
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0013 0.0084 0.0115
Treponema pallidum cell division protein FtsZ 0.0014 0.009 0.017
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0008 0.0018 0.0053
Plasmodium vivax tubulin beta chain, putative 0.0032 0.0317 0.1863
Echinococcus multilocularis tubulin alpha 1C chain 0.0032 0.0317 0.0317
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Mycobacterium ulcerans hypothetical protein 0.0019 0.0153 0.0451
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Loa Loa (eye worm) hypothetical protein 0.0062 0.0686 0.1959
Mycobacterium tuberculosis Conserved protein 0.0043 0.0451 0.1353
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0008 0.0018 0.0025
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0009 0.0023 0.0023
Echinococcus granulosus pangolin 0.0058 0.0633 0.0873
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0008 0.0018 0.0042
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0018 0.0143 0.0336
Trypanosoma cruzi aldo/keto reductase, putative 0.0066 0.0734 0.4309
Echinococcus granulosus tubulin alpha chain 0.0032 0.0317 0.0437
Schistosoma mansoni DNA polymerase eta 0.0059 0.0655 0.0902
Plasmodium vivax replication factor C subunit 1, putative 0.001 0.0035 0.0205
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.002 0.016 0.0221
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0051 0.0119
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Echinococcus multilocularis beta tubulin 0.0032 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.001 0.0035 0.0099
Loa Loa (eye worm) hypothetical protein 0.0072 0.0811 0.2315
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0012 0.0059 0.0428
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Brugia malayi Muscleblind-like protein 0.0121 0.1424 0.4068
Trichomonas vaginalis tubulin alpha chain, putative 0.0018 0.0143 0.0336
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0275 0.3334 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0671 0.0671
Trichomonas vaginalis tubulin epsilon chain, putative 0.0014 0.009 0.0212
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0008 0.0018 0.0042
Schistosoma mansoni Lysine-specific histone demethylase 1 0.002 0.016 0.0221
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0009 0.0023 0.0032
Onchocerca volvulus 0.0035 0.0357 0.2582
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0051 0.0119
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0008 0.0018 0.0053
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0023 0.0203 0.0437
Brugia malayi tubulin alpha-2 chain 0.0032 0.0317 0.0906
Brugia malayi Glycosyl hydrolases family 31 protein 0.0139 0.1649 0.471
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0132 0.0181
Onchocerca volvulus 0.0051 0.0544 0.3937
Schistosoma mansoni hypothetical protein 0.0071 0.0798 0.1099
Trichomonas vaginalis tubulin alpha chain, putative 0.0032 0.0317 0.0745
Schistosoma mansoni ets 0.0011 0.0047 0.0064
Loa Loa (eye worm) hypothetical protein 0.0043 0.0451 0.1288
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Schistosoma mansoni tubulin subunit beta 0.0014 0.009 0.0124
Plasmodium vivax P-type ATPase4, putative 0.0008 0.0018 0.0106
Entamoeba histolytica hypothetical protein 0.0071 0.0798 0.1873
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0051 0.0119
Plasmodium vivax SET domain protein, putative 0.0011 0.0051 0.03
Echinococcus multilocularis cation transporting atpase worm 0.0008 0.0018 0.0018
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0023 0.0203 0.061
Brugia malayi ABC transporter family protein 0.0011 0.0051 0.0144
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Loa Loa (eye worm) hypothetical protein 0.0121 0.1424 0.4068
Echinococcus multilocularis phosphoserine phosphatase 0.0008 0.0018 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Trypanosoma brucei unspecified product 0.0039 0.0398 0.2335
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Entamoeba histolytica P-glycoprotein-5 0.0011 0.0051 0.0119
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0008 0.0018 0.0042
Echinococcus multilocularis tubulin alpha 3 chain 0.0032 0.0317 0.0317
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0031 0.0301 0.1765
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0349 0.4259 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0014 0.009 0.053
Leishmania major DNA polymerase kappa, putative 0.0012 0.0065 0.0384
Trichomonas vaginalis tubulin beta chain, putative 0.0032 0.0317 0.0745
Echinococcus multilocularis cation transporting ATPase 13A1 0.0008 0.0018 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0202 0.0577
Leishmania major prostaglandin f synthase, putative 0.0066 0.0734 0.4309
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0009 0.0023 0.0067
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0008 0.0018 0.0106
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0047 0.0064
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0051 0.0119
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0009 0.0023 0.0023
Loa Loa (eye worm) tubulin alpha chain 0.0032 0.0317 0.0906
Loa Loa (eye worm) tubulin alpha-3 chain 0.0014 0.009 0.0258
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0817 0.0817
Brugia malayi alpha-tubulin 0.0032 0.0317 0.0906
Echinococcus granulosus tubulin alpha chain 0.0032 0.0317 0.0437
Echinococcus multilocularis Tubulin beta 2C chain 0.0032 0.0317 0.0317
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0008 0.0018 0.0025
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0051 0.0119
Loa Loa (eye worm) intermediate filament protein 0.0023 0.0203 0.0579
Brugia malayi E1-E2 ATPase family protein 0.0008 0.0018 0.0051
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0008 0.0018 0.0106
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Echinococcus granulosus cation transporting ATPase 13A3 0.0008 0.0018 0.0025
Brugia malayi Protein kinase domain containing protein 0.0036 0.0363 0.1037
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0202 0.0577
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0019 0.0153 0.0897
Trypanosoma cruzi aldo-keto reductase 0.0066 0.0734 0.4309
Entamoeba histolytica aldose reductase, putative 0.0066 0.0734 0.1722
Trypanosoma brucei glycosyl hydrolase-like protein 0.0012 0.0059 0.0348
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0008 0.0018 0.0106
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0451 0.2649
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0011 0.0051 0.0144
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0008 0.0018 0.0053
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0013 0.0084 0.0084
Trichomonas vaginalis tubulin beta chain, putative 0.0032 0.0317 0.0745
Entamoeba histolytica tubulin family protein 0.0032 0.0317 0.0745
Loa Loa (eye worm) tubulin beta chain 0.0032 0.0317 0.0906
Brugia malayi topoisomerase 0.001 0.0035 0.0099
Onchocerca volvulus 0.002 0.016 0.116
Plasmodium falciparum aldehyde reductase, putative 0.0019 0.0153 0.0897
Trichomonas vaginalis tubulin gamma chain, putative 0.0032 0.0317 0.0745
Giardia lamblia Alpha-tubulin 0.0032 0.0317 0.0705
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0008 0.0018 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0011 0.0051 0.007
Trichomonas vaginalis tubulin, putative 0.0018 0.0143 0.0336
Loa Loa (eye worm) hypothetical protein 0.0023 0.0198 0.0564
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0398 0.0398
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0009 0.0023 0.0067
Loa Loa (eye worm) hypothetical protein 0.0044 0.0459 0.1312
Loa Loa (eye worm) TK/ROR protein kinase 0.0036 0.0363 0.1037
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0028 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0032 0.0317 0.0906
Brugia malayi Ets-domain containing protein 0.0011 0.0047 0.0133
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Toxoplasma gondii DNA topoisomerase 2, putative 0.0107 0.1252 0.7353
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0107 0.1252 0.3575
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0065 0.0384
Leishmania major copper-transporting ATPase-like protein, putative 0.0008 0.0018 0.0106
Brugia malayi Glycosyl hydrolases family 31 protein 0.0031 0.0301 0.0858
Schistosoma mansoni hypothetical protein 0.0011 0.0047 0.0064
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0301 0.1765
Schistosoma mansoni hypothetical protein 0.0035 0.0357 0.0492
Onchocerca volvulus Bile acid receptor homolog 0.0009 0.0023 0.017
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0121 0.1415 0.8313
Trichomonas vaginalis maltase-glucoamylase, putative 0.0012 0.0059 0.0139
Trypanosoma brucei unspecified product 0.0027 0.0248 0.1457
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0008 0.0018 0.0088
Echinococcus granulosus FTZ F1 alpha 0.0009 0.0023 0.0032
Schistosoma mansoni tubulin subunit beta 0.0032 0.0317 0.0437
Echinococcus granulosus histone lysine methyltransferase setb 0.0028 0.0267 0.0368
Echinococcus granulosus microtubule associated protein 2 0.059 0.7257 1
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0023 0.0203 0.1194
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0008 0.0018 0.0106
Loa Loa (eye worm) hypothetical protein 0.0059 0.0655 0.187
Plasmodium vivax multidrug resistance protein 1, putative 0.0011 0.0051 0.0297
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0009 0.0023 0.0067
Giardia lamblia Gamma tubulin 0.0032 0.0317 0.0705
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4259 1
Onchocerca volvulus 0.0066 0.0734 0.5309
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0011 0.0051 0.0051
Loa Loa (eye worm) tubulin alpha 2 0.0018 0.0143 0.0408
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0035 0.0082
Trypanosoma brucei polyadenylate-binding protein 2 0.0007 0.0008 0.0046
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0.0051 0.0119
Trypanosoma brucei beta tubulin 0.0032 0.0317 0.1863
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0051 0.0119
Trypanosoma cruzi beta tubulin, putative 0.0032 0.0317 0.1863
Echinococcus granulosus peroxisome assembly protein 26 0.0032 0.0317 0.0437
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.0153 0.0359
Echinococcus multilocularis dna polymerase eta 0.0059 0.0655 0.0655
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0051 0.007
Trypanosoma brucei zeta tubulin 0.0014 0.009 0.053
Schistosoma mansoni tubulin subunit beta 0.0032 0.0317 0.0437
Mycobacterium ulcerans dehydrogenase 0.002 0.016 0.0473
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0451 0.0451
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0301 0.0706
Mycobacterium ulcerans hypothetical protein 0.0012 0.0065 0.0193
Echinococcus granulosus tyrosine protein kinase shark 0.008 0.0906 0.1248
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0051 0.0119
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0051 0.0119
Onchocerca volvulus Protein ultraspiracle homolog 0.0009 0.0023 0.017
Trypanosoma cruzi polyadenylate-binding protein 1, putative 0.0007 0.0008 0.0046
Loa Loa (eye worm) tubulin beta chain 0.0014 0.009 0.0258
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0051 0.0119
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0009 0.0023 0.0032
Schistosoma mansoni polyadenylate binding protein 0.0007 0.0008 0.0011
Schistosoma mansoni multidrug resistance protein 0.0011 0.0051 0.007
Brugia malayi hypothetical protein 0.0086 0.098 0.2798
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0011 0.0051 0.0297
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Chlamydia trachomatis DNA gyrase subunit B 0.0063 0.0695 1
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0012 0.0059 0.0348
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0132 0.0181
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0059 0.0647 0.1849
Echinococcus multilocularis aldo keto reductase 0.0066 0.0734 0.0734
Leishmania major mitochondrial DNA topoisomerase II 0.0121 0.1415 0.8313
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0018 0.0143 0.0408
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0067
Schistosoma mansoni alpha-glucosidase 0.012 0.1408 0.194
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0171 0.2037 0.602
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0734 0.1011
Echinococcus multilocularis beta catenin 0.0119 0.1392 0.1392
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4259 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0051 0.0119
Schistosoma mansoni intermediate filament proteins 0.0023 0.0203 0.028
Brugia malayi polk-prov protein 0.0012 0.0065 0.0187
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0426 0.0587
Echinococcus multilocularis ets variant gene 4 0.0011 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0072 0.0812 0.1119
Giardia lamblia Aldose reductase 0.0066 0.0734 0.1687
Echinococcus granulosus tubulin beta 4A class IVa 0.0032 0.0317 0.0437
Trichomonas vaginalis cation-transporting ATPase, putative 0.0008 0.0018 0.0042
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0171 0.2037 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0734 0.0734
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0051 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0267 0.0368
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Chlamydia trachomatis DNA gyrase subunit A 0.0023 0.0203 0.2737
Trypanosoma brucei epsilon tubulin 0.0032 0.0317 0.1863
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.013 0.0763
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0008 0.0018 0.0054
Schistosoma mansoni tubulin subunit beta 0.0032 0.0317 0.0437
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0035 0.0205
Schistosoma mansoni microtubule-associated protein tau 0.059 0.7257 1
Echinococcus granulosus voltage gated potassium channel subunit 0.0019 0.0153 0.0211
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0051
Plasmodium falciparum cysteine repeat modular protein 1 0.0035 0.0357 0.2096
Loa Loa (eye worm) hypothetical protein 0.0043 0.0451 0.1288
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0047 0.0064
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0035 0.0082
Leishmania major calcium-translocating P-type ATPase 0.0008 0.0018 0.0106
Loa Loa (eye worm) hypothetical protein 0.0011 0.0047 0.0133
Onchocerca volvulus 0.0066 0.0734 0.5309
Schistosoma mansoni alpha tubulin 0.0032 0.0317 0.0437
Schistosoma mansoni topbp1 0.001 0.0035 0.0048
Echinococcus multilocularis Tubulin beta 2C chain 0.0032 0.0317 0.0317
Echinococcus multilocularis expressed conserved protein 0.009 0.1032 0.1032
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0009 0.0023 0.0023
Echinococcus granulosus tubulin alpha chain 0.0032 0.0317 0.0437
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0008 0.0018 0.0106
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0063 0.0695 0.1596
Mycobacterium leprae Conserved hypothetical protein 0.0047 0.0497 0.2438
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0067
Echinococcus multilocularis tubulin subunit beta 0.0032 0.0317 0.0317
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0073 0.0819 0.5925
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0202 0.0597
Trypanosoma cruzi alpha tubulin, putative 0.0032 0.0317 0.1863
Echinococcus multilocularis ATP binding cassette sub family B 0.0011 0.0049 0.0049
Echinococcus granulosus tubulin alpha 1C chain 0.0032 0.0317 0.0437
Onchocerca volvulus 0.001 0.0035 0.0252
Onchocerca volvulus 0.0009 0.0023 0.017
Trypanosoma cruzi ISWI complex protein 0.0016 0.0109 0.0643
Echinococcus granulosus cation transporting atpase worm 0.0008 0.0018 0.0025
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0259 0.314 0.9419
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0202 0.1188
Trichomonas vaginalis tubulin epsilon chain, putative 0.0032 0.0317 0.0745
Loa Loa (eye worm) hypothetical protein 0.0051 0.0548 0.1567
Loa Loa (eye worm) tubulin alpha 2 0.0018 0.0143 0.0408
Loa Loa (eye worm) hypothetical protein 0.0011 0.0047 0.0133
Schistosoma mansoni ATPase 0.0008 0.0018 0.0025
Leishmania major beta tubulin 0.0032 0.0317 0.1863
Brugia malayi RNA binding protein 0.0109 0.1277 0.3648
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0051 0.0119
Trypanosoma cruzi UDP-galactopyranose mutase 0.002 0.016 0.0941
Mycobacterium ulcerans cell division protein FtsZ 0.0014 0.009 0.0266
Echinococcus granulosus lamin 0.0023 0.0203 0.028
Leishmania major DNA polymerase eta, putative 0.0033 0.0323 0.1895
Mycobacterium leprae Possible oxidoreductase 0.0019 0.0153 0.075
Onchocerca volvulus 0.0066 0.0734 0.5309
Plasmodium vivax polyadenylate-binding protein, putative 0.0007 0.0008 0.0046
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0008 0.0018 0.0106
Echinococcus multilocularis Tubulin alpha 1 chain 0.0032 0.0317 0.0317
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0008 0.0018 0.0018
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0047 0.0047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0118 0.0354
Trypanosoma brucei polyadenylate-binding protein 1 0.0007 0.0008 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4259 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0009 0.0023 0.0032
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0012 0.007 0.0199
Plasmodium vivax DNA gyrase subunit A, putative 0.0023 0.0203 0.1194
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0008 0.0018 0.0106
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0008 0.0018 0.0042
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0047 0.0047
Trichomonas vaginalis tubulin epsilon chain, putative 0.0032 0.0317 0.0745
Trypanosoma brucei DNA topoisomerase ii 0.0121 0.1415 0.8313
Echinococcus granulosus lysosomal alpha glucosidase 0.0139 0.1649 0.2272
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0798 0.1099
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0023 0.0032
Schistosoma mansoni hypothetical protein 0.0013 0.0084 0.0115
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0008 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0012 0.0065 0.0187
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0035 0.0082
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0032 0.0317 0.0745
Schistosoma mansoni aldo-keto reductase 0.0066 0.0734 0.1011
Trypanosoma brucei alpha tubulin 0.0032 0.0317 0.1863
Schistosoma mansoni tubulin subunit alpha 0.0014 0.009 0.0124
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0398 0.1193
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0047 0.0064
Trypanosoma brucei zeta tubulin, putative 0.0014 0.009 0.053
Loa Loa (eye worm) hypothetical protein 0.0043 0.0451 0.1288
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0451 0.1059
Trypanosoma brucei P-type H+-ATPase, putative 0.0008 0.0018 0.0106
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.0109 0.1277 0.176
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0008 0.0018 0.0106
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4259 1
Brugia malayi Latrophilin receptor protein 2 0.0013 0.0084 0.0239
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0008 0.0018 0.0051
Onchocerca volvulus 0.0018 0.0143 0.1035
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0734 0.1011
Loa Loa (eye worm) hypothetical protein 0.0109 0.1277 0.3648
Loa Loa (eye worm) hypothetical protein 0.0008 0.0018 0.0051
Entamoeba histolytica hypothetical protein 0.0071 0.0798 0.1873
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0008 0.0018 0.0106
Schistosoma mansoni coup transcription factor 0.0009 0.0023 0.0032
Brugia malayi NADH-dependent xylose reductase 0.0019 0.0153 0.0436
Schistosoma mansoni eukaryotic translation initiation factor 4h 0.0109 0.1277 0.176
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0144 0.1702 1
Mycobacterium ulcerans beta-lactamase 0.0043 0.0451 0.1332
Schistosoma mansoni tyrosine kinase 0.008 0.0906 0.1248
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0051 0.0051
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0047 0.0064
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0008 0.0018 0.0025
Schistosoma mansoni bromodomain containing protein 0.0064 0.0716 0.0987
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.001 0.0035 0.0103
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0202 0.0992
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0035 0.0048
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0451 0.0621
Entamoeba histolytica aldose reductase, putative 0.0066 0.0734 0.1722
Loa Loa (eye worm) tubulin alpha-2 chain 0.0032 0.0317 0.0906
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0066 0.0734 0.2095
Echinococcus multilocularis cation transporting ATPase 13A3 0.0008 0.0018 0.0018
Schistosoma mansoni elf1 0.0011 0.0047 0.0064
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0019 0.0153 0.0211
Echinococcus multilocularis Tubulin beta 2C chain 0.0032 0.0317 0.0317
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0008 0.0018 0.0106
Trypanosoma cruzi polyadenylate-binding protein, putative 0.0007 0.0008 0.0046
Trypanosoma cruzi ISWI complex protein 0.0016 0.0109 0.0643
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0019 0.0153 0.0359
Schistosoma mansoni zinc finger protein 0.002 0.0164 0.0225
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0451 0.1332
Schistosoma mansoni eyes absent homolog 0.0086 0.098 0.135
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0349 0.4259 1
Plasmodium falciparum multidrug resistance protein 1 0.0011 0.0051 0.0297
Trichomonas vaginalis tubulin beta chain, putative 0.0018 0.0143 0.0336
Loa Loa (eye worm) oxidoreductase 0.0066 0.0734 0.2095
Echinococcus granulosus intermediate filament protein 0.0023 0.0203 0.028
Schistosoma mansoni hypothetical protein 0.0013 0.0084 0.0115
Plasmodium falciparum tubulin gamma chain 0.0032 0.0317 0.1863
Echinococcus multilocularis GPCR, family 2 0.0013 0.0084 0.0084
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0008 0.0018 0.0051
Loa Loa (eye worm) steroid hormone receptor 0.0009 0.0023 0.0067
Echinococcus granulosus hypothetical protein 0.0267 0.3239 0.4464
Loa Loa (eye worm) calcium ATPase 0.0008 0.0018 0.0051
Echinococcus multilocularis muscleblind protein 1 0.0121 0.1424 0.1424
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.009 0.0212
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.016 0.0221
Loa Loa (eye worm) hypothetical protein 0.0009 0.0023 0.0067
Echinococcus multilocularis tubulin alpha 1C chain 0.0032 0.0317 0.0317
Trichomonas vaginalis cation-transporting ATPase, putative 0.0008 0.0018 0.0042
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0008 0.0018 0.0106
Plasmodium vivax tubulin gamma chain, putative 0.0032 0.0317 0.1863
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0202 0.0606
Schistosoma mansoni DNA topoisomerase type I 0.0144 0.1702 0.2346
Trichomonas vaginalis tubulin alpha chain, putative 0.0018 0.0143 0.0336
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0051 0.007
Echinococcus multilocularis Tubulin beta 2C chain 0.0032 0.0317 0.0317
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0051 0.0119
Brugia malayi hypothetical protein 0.001 0.0035 0.0099
Toxoplasma gondii polyadenylate binding protein, putative 0.0007 0.0008 0.0046
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0009 0.0023 0.0032
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0107 0.1252 0.3575
Trypanosoma brucei beta tubulin 0.0032 0.0317 0.1863
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0008 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0071 0.0798 0.1873
Chlamydia trachomatis protoporphyrinogen oxidase 0.002 0.016 0.2101
Echinococcus granulosus phospholipid transporting ATPase VA 0.0008 0.0018 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0023 0.0023
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0734 0.1722
Echinococcus granulosus neuropeptide s receptor 0.0396 0.4835 0.6663
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Echinococcus multilocularis tubulin subunit TubB 0.0032 0.0317 0.0317
Echinococcus multilocularis neuropeptide s receptor 0.0396 0.4835 0.4835
Echinococcus granulosus tubulin delta chain 0.0014 0.009 0.0124
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0009 0.0023 0.0023
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0035 0.0082
Echinococcus granulosus zinc finger protein 0.002 0.0164 0.0225
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0248 0.1457
Trypanosoma brucei cation-transporting ATPase, putative 0.0008 0.0018 0.0106
Loa Loa (eye worm) hypothetical protein 0.0086 0.098 0.2798
Leishmania major DNA polymerase kappa, putative 0.0039 0.0398 0.2335
Echinococcus multilocularis lysosomal alpha glucosidase 0.0139 0.1649 0.1649
Loa Loa (eye worm) hypothetical protein 0.0023 0.0202 0.0577
Trypanosoma brucei beta tubulin 0.0032 0.0317 0.1863
Echinococcus granulosus GPCR family 2 0.0013 0.0084 0.0115
Mycobacterium ulcerans monoamine oxidase 0.002 0.016 0.0473
Echinococcus granulosus tubulin subunit beta 0.0032 0.0317 0.0437
Mycobacterium ulcerans glutaminase 0.0222 0.2676 0.7907
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0202 0.0597
Echinococcus multilocularis tubulin alpha chain 0.0032 0.0317 0.0317
Onchocerca volvulus 0.0008 0.0018 0.013
Loa Loa (eye worm) hypothetical protein 0.0288 0.3501 1
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0451 0.2649
Entamoeba histolytica P-glycoprotein-1 0.0011 0.0051 0.0119
Echinococcus granulosus muscleblind protein 0.0121 0.1424 0.1963
Leishmania major DNA topoisomerase ii 0.0102 0.118 0.6929
Echinococcus multilocularis lysosomal alpha glucosidase 0.0139 0.1649 0.1649
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0051 0.007
Entamoeba histolytica tubulin alpha chain, putative 0.0032 0.0317 0.0745
Leishmania major alpha tubulin 0.0032 0.0317 0.1863
Schistosoma mansoni hypothetical protein 0.004 0.0408 0.0562
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0008 0.0018 0.0053
Brugia malayi polyadenylate-binding protein 1 0.0007 0.0008 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0398 0.2335

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 16 uM Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior substrate addition measured for 10 mins by spectrophotometry ChEMBL. 22285569

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.