Detailed information for compound 1587222

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 486.521 | Formula: C23H30N6O6
  • H donors: 2 H acceptors: 3 LogP: 1.72 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1c(ccc(c1OC)OC)CN1CCN(CC1)Cc1ccc(cc1[N+](=O)[O-])C(=O)N=C(N)N
  • InChi: 1S/C23H30N6O6/c1-33-19-7-6-17(20(34-2)21(19)35-3)14-28-10-8-27(9-11-28)13-16-5-4-15(12-18(16)29(31)32)22(30)26-23(24)25/h4-7,12H,8-11,13-14H2,1-3H3,(H4,24,25,26,30)
  • InChiKey: RYJLAOOTBSUKSD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Sodium/hydrogen exchanger 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus sodium:hydrogen exchanger Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) Get druggable targets OG5_127664 All targets in OG5_127664
Giardia lamblia Sodium/hydrogen exchanger 3 Get druggable targets OG5_127664 All targets in OG5_127664
Loa Loa (eye worm) NHE-3 Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) Get druggable targets OG5_127664 All targets in OG5_127664
Loa Loa (eye worm) sodium/hydrogen exchanger Get druggable targets OG5_127664 All targets in OG5_127664
Schistosoma japonicum Sodium/hydrogen exchanger 2, putative Get druggable targets OG5_127664 All targets in OG5_127664
Onchocerca volvulus Sodium\/hydrogen exchanger homolog Get druggable targets OG5_127664 All targets in OG5_127664
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127664 All targets in OG5_127664
Brugia malayi sodium/hydrogen exchanger 3 family protein Get druggable targets OG5_127664 All targets in OG5_127664
Onchocerca volvulus Sodium\/hydrogen exchanger homolog Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus multilocularis sodium:hydrogen exchanger Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 Get druggable targets OG5_127664 All targets in OG5_127664
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) Get druggable targets OG5_127664 All targets in OG5_127664
Schistosoma japonicum ko:K03316 monovalent cation:H+ antiporter, CPA1 family, putative Get druggable targets OG5_127664 All targets in OG5_127664
Loa Loa (eye worm) sodium/hydrogen exchanger 3 family protein Get druggable targets OG5_127664 All targets in OG5_127664
Onchocerca volvulus Sodium\/hydrogen exchanger homolog Get druggable targets OG5_127664 All targets in OG5_127664
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 Get druggable targets OG5_127664 All targets in OG5_127664
Schistosoma mansoni sodium/hydrogen exchanger Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus multilocularis sodium:hydrogen exchanger Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus granulosus sodium:hydrogen exchanger 2 (nhe2) Get druggable targets OG5_127664 All targets in OG5_127664
Echinococcus granulosus sodium:hydrogen exchanger Get druggable targets OG5_127664 All targets in OG5_127664
Schistosoma mansoni sodium/hydrogen exchanger 2 (nhe2) Get druggable targets OG5_127664 All targets in OG5_127664
Schistosoma japonicum Sodium/hydrogen exchanger 2, putative Get druggable targets OG5_127664 All targets in OG5_127664
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.001 0.0078
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0074 0.0175 0.1053
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0059 0.0129 0.0129
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0139 0.0508
Trichomonas vaginalis hypothetical protein 0.0028 0.0036 0.0219
Echinococcus granulosus Diacylglycerol kinase zeta 0.0074 0.0175 0.0175
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0391 0.0391
Trypanosoma cruzi major cysteine proteinase, putative 0.0048 0.0098 0.036
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0292
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0291 0.0508
Brugia malayi PHD-finger family protein 0.0043 0.0081 0.0299
Echinococcus granulosus Diacylglycerol kinase theta 0.0074 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0197
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0053 0.0053
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0065 0.0149 0.0546
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0074 0.0175 0.0306
Mycobacterium leprae Probable lipase LipE 0.0038 0.0065 0.1169
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0139 0.0139
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0021 0.042
Trichomonas vaginalis protein kinase inhibitor, putative 0.0061 0.0137 0.0822
Brugia malayi nuclear receptor NHR-88 0.0033 0.0053 0.0194
Onchocerca volvulus 0.0019 0.0009 0.012
Schistosoma mansoni jumonji/arid domain-containing protein 0.0077 0.0185 0.0185
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0291 0.0508
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0071 0.0167 0.0167
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0051 0.0089
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0327
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0042 0.0042
Trypanosoma cruzi Na/H antiporter-like protein, putative 0.0019 0.0009 0.0032
Schistosoma mansoni ran 0.0021 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0038 0.0065 0.0114
Brugia malayi MH2 domain containing protein 0.0017 0.0002 0.0008
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0091 0.055
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0033 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0091 0.1859
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0086 0.0516
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0026 0.0029 0.0172
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Leishmania major importin beta-1 subunit, putative 0.0024 0.0023 0.0083
Schistosoma mansoni ferritin light chain 0.0027 0.0032 0.0032
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0044 0.0086 0.0311
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0014 0.001
Onchocerca volvulus 0.0038 0.0065 0.0905
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0044 0.0086 0.0314
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0167 0.0615
Schistosoma mansoni hypothetical protein 0.0287 0.0825 0.0825
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0014 0.001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0065 0.0114
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.01 0.0255 0.0255
Trichomonas vaginalis bmru protein, putative 0.0074 0.0175 0.1053
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0086 0.0516
Brugia malayi Diacylglycerol kinase protein 2 0.0074 0.0175 0.0645
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0014 0.0086
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0197
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0071 0.0167 0.0292
Echinococcus multilocularis sterol regulatory element binding protein 0.0082 0.02 0.02
Schistosoma mansoni ran 0.0021 0.0016 0.0016
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.003 0.0111
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0079 0.0192 0.0192
Schistosoma mansoni sodium/hydrogen exchanger 0.01 0.0255 0.0255
Echinococcus multilocularis sodium:hydrogen exchanger 0.01 0.0255 0.0255
Brugia malayi heat shock protein 90 0.0033 0.0051 0.0187
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0014 0.0053
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0048 0.0048
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0124 0.0747
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0023 0.0083
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0027
Brugia malayi MH1 domain containing protein 0.0017 0.0002 0.0008
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0026 0.0029 0.005
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0044 0.0086 0.0086
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0291 0.0291
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0261 0.0952
Toxoplasma gondii Na+/H+ exchanger NHE1 0.0019 0.0009 0.0066
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.001 0.0036
Trichomonas vaginalis heat shock protein, putative 0.0026 0.003 0.0183
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0047 0.0359
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0175 0.0638
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0015
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0185 0.0514 0.0514
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.003 0.003
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0167 0.0615
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0014 0.0053
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0906 0.2715 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0038 0.0065 0.0114
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0065 0.024
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0167 0.0167
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0071 0.0167 0.0292
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0054 0.0199
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0053 0.0732
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0177 0.0492 0.0852
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0319 0.0926 0.1619
Giardia lamblia DINP protein human, muc B family 0.0081 0.0197 0.1781
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0065 0.0104
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Brugia malayi ecdysone receptor 0.0033 0.0053 0.0194
Echinococcus granulosus microtubule associated protein 2 0.2058 0.6235 0.6235
Trypanosoma cruzi sodium/hydrogen exchanger, putative 0.0019 0.0009 0.0032
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0065 0.0392
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0014 0.0052
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0139 0.0139
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0001 0.0001
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0001 0.0001
Schistosoma mansoni nuclear receptor 0.0033 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.01 0.0255 0.0446
Echinococcus multilocularis phosphoglycerate kinase 1 0.0177 0.0492 0.0492
Echinococcus granulosus smad 0.0017 0.0002 0.0002
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0177 0.0492 0.2958
Onchocerca volvulus 0.0074 0.0175 0.2435
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0291 0.0291
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.003 0.0111
Echinococcus multilocularis ecdysone induced protein 78C 0.0071 0.0167 0.0167
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.004 0.0142
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0073 0.0597
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0016 0.0028
Trypanosoma brucei DNA polymerase IV, putative 0.0095 0.024 0.0875
Brugia malayi Sodium/hydrogen exchanger 8 0.0019 0.0009 0.0032
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0048 0.0174
Onchocerca volvulus 0.0071 0.0168 0.233
Echinococcus granulosus neuropeptide receptor A26 0.0941 0.2824 0.2824
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0103 0.0103
Entamoeba histolytica hypothetical protein 0.0024 0.0023 0.004
Brugia malayi Pre-SET motif family protein 0.0036 0.0061 0.0225
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0002 0.0002
Schistosoma mansoni bromodomain containing protein 0.0021 0.0016 0.0016
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0071 0.0167 0.0167
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0181 0.1384
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0261 0.0952
Schistosoma mansoni hypothetical protein 0.3292 1 1
Leishmania major cathepsin L-like protease 0.0062 0.0139 0.0508
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0102 0.0372
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0051 0.0186
Echinococcus granulosus zinc finger protein 0.0037 0.0064 0.0064
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0044 0.0086 0.0316
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0181 0.3572
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0014 0.0016
Brugia malayi nuclear receptor NHR-88 0.0071 0.0167 0.0615
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0082 0.02 0.0351
Loa Loa (eye worm) NHE-3 0.01 0.0255 0.0446
Leishmania major hypothetical protein, conserved 0.0016 0.0001 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0061 0.0061
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0048 0.0048
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0014 0.0052
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0184
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0191 0.0533 0.0932
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0023 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0127 0.0463
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0124 0.0124
Brugia malayi phosphofructokinase 0.0111 0.0291 0.107
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0912 0.2734 1
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Onchocerca volvulus 0.0033 0.0053 0.0732
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0014 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.004 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0036 0.0219
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0228 0.0228
Brugia malayi beta-lactamase family protein 0.0038 0.0065 0.024
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0044 0.0086 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Schistosoma mansoni retinoic acid receptor RXR 0.0071 0.0167 0.0167
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0181 0.3685
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0005 0.0005
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0044 0.0086 0.0516
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0026 0.0029 0.0105
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0002 0.0002
Trichomonas vaginalis ferritin, putative 0.0027 0.0032 0.0191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0071 0.0167 0.0292
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0071 0.0167 0.0292
Onchocerca volvulus 0.0021 0.0014 0.0199
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0021 0.0073
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0168 0.0293
Trichomonas vaginalis heat shock protein, putative 0.0026 0.003 0.0183
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0228 0.0228
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0228 0.0228
Loa Loa (eye worm) sodium-hydrogen exchanger NHE1 0.0019 0.0009 0.0015
Trypanosoma brucei heat shock protein, putative 0.0033 0.0051 0.0183
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0072 0.0072
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0291 0.0508
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0014 0.0109
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0021 0.0073
Schistosoma mansoni importin beta-1 0.0029 0.004 0.004
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0065 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.0105 0.0382
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0071 0.0167 0.0615
Schistosoma mansoni hypothetical protein 0.0619 0.184 0.184
Brugia malayi Phosphoglycerate kinase 0.0065 0.0149 0.055
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0292
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0044 0.0086 0.0086
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0028 0.0101
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0047 0.0094 0.0094
Echinococcus granulosus tar DNA binding protein 0.0062 0.0141 0.0141
Echinococcus granulosus expressed protein 0.0027 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0512 0.1514 0.1514
Onchocerca volvulus 0.005 0.0103 0.1436
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0065 0.0065
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.01 0.0257 0.045
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0057 0.0099
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0001 0.0003
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0044 0.0086 0.0086
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0044 0.0086 0.0086
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0065 0.0104
Loa Loa (eye worm) latrophilin receptor protein 2 0.0287 0.0825 0.1444
Loa Loa (eye worm) hypothetical protein 0.0071 0.0168 0.0293
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.1743
Trypanosoma brucei phosphoglycerate kinase 0.0177 0.0492 0.1797
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0014 0.0053
Echinococcus multilocularis expressed protein 0.0047 0.0094 0.0094
Leishmania major hypothetical protein, conserved 0.0038 0.0065 0.0238
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.003 0.0611
Schistosoma mansoni coup transcription factor 0.0071 0.0167 0.0167
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0026 0.0029 0.0581
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0044 0.0086 0.0086
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0002 0.0004
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.0032 0.0046
Brugia malayi intermediate filament protein 0.0053 0.0111 0.041
Loa Loa (eye worm) hypothetical protein 0.0074 0.0176 0.0307
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0026 0.0029 0.0029
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0037 0.0135
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0051 0.0183
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.1889 0.5716 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0065 0.0114
Loa Loa (eye worm) MBCTL1 0.0057 0.0124 0.0218
Echinococcus granulosus endoplasmin 0.0026 0.003 0.003
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0177 0.0492 0.18
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0025 0.0507
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0233 0.0662 0.1159
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0044 0.0086 0.0314
Loa Loa (eye worm) DnaJ domain-containing protein 0.0061 0.0137 0.0239
Echinococcus multilocularis lamin dm0 0.0053 0.0111 0.0111
Echinococcus multilocularis musashi 0.0053 0.0111 0.0111
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0074 0.0176 0.0176
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0291 0.0508
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0255
Echinococcus granulosus fetal alzheimer antigen falz 0.0037 0.0063 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0167 0.0615
Schistosoma mansoni smad 0.0017 0.0002 0.0002
Entamoeba histolytica diacylglycerol kinase, putative 0.0074 0.0175 0.0306
Brugia malayi Ceramide kinase 0.0074 0.0175 0.0645
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0001 0.0001
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Schistosoma mansoni sphingoid long chain base kinase 0.1889 0.5716 0.5716
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.0081 0.0197 0.0197
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0103 0.0103
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.001 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0015
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0161 0.0281
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0086 0.0314
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0014 0.0016
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0016 0.0016
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0044 0.0086 0.1743
Loa Loa (eye worm) acetyltransferase 0.0151 0.0412 0.072
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0149
Trypanosoma brucei heat shock protein, putative 0.0033 0.0051 0.0183
Echinococcus granulosus intestinal type alkaline phosphatase 0.0169 0.0468 0.0468
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0044 0.0086 0.015
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0161 0.0281
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0197
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0091 0.055
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0074 0.0175 0.0175
Schistosoma mansoni sodium/hydrogen exchanger 2 (nhe2) 0.01 0.0255 0.0255
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0014 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Mycobacterium ulcerans lipase LipD 0.0038 0.0065 0.0099
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0042 0.0255
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.0047 0.0047
Loa Loa (eye worm) oxidoreductase 0.0021 0.0014 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0025 0.0149
Trichomonas vaginalis sphingosine kinase, putative 0.0074 0.0175 0.1053
Trichomonas vaginalis rotamase, putative 0.0035 0.0057 0.0342
Chlamydia trachomatis phosphoglycerate kinase 0.0177 0.0492 1
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0044 0.0086 0.0086
Brugia malayi latrophilin 2 splice variant baaae 0.0619 0.184 0.6778
Brugia malayi CXXC zinc finger family protein 0.0231 0.0656 0.2417
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.001 0.001
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0001 0.0001
Plasmodium vivax SET domain protein, putative 0.0036 0.0061 0.124
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0054 0.0415
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0065 0.0392
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0042 0.0324
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0311
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0104 0.0172
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0025 0.0191
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0014 0.0052
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0021 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0021 0.0076
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.01 0.0255 0.0255
Brugia malayi hypothetical protein 0.0019 0.0009 0.0032
Trypanosoma brucei DNA polymerase eta, putative 0.01 0.0257 0.0939
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0014 0.0014
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0074 0.0175 0.1053
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.0185 0.0324
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0042 0.0863
Echinococcus granulosus GPCR family 2 0.0287 0.0825 0.0825
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0044 0.0086 0.0311
Brugia malayi hypothetical protein 0.0036 0.0061 0.0223
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0175 0.0641
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0104 0.0172
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0074 0.0175 0.0175
Plasmodium falciparum sodium/hydrogen exchanger, Na+, H+ antiporter 0.0019 0.0009 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0071 0.0167 0.0615
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0141 0.0141
Schistosoma mansoni hypothetical protein 0.0315 0.0914 0.0914
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0074 0.0176 0.0176
Trypanosoma brucei Sphingosine kinase 0.0074 0.0175 0.0638
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0053 0.0053
Brugia malayi CHE-14 protein 0.0082 0.02 0.0738
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0097 0.0097
Loa Loa (eye worm) sodium/hydrogen exchanger 3 family protein 0.01 0.0255 0.0446
Onchocerca volvulus 0.0048 0.0097 0.1351
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0261 0.0954
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0185 0.0514 0.0514
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0181 0.3685
Echinococcus multilocularis ferritin 0.0027 0.0032 0.0032
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0291 0.0499
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0114
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0364 0.1061 0.1061
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.001 0.0037
Trichomonas vaginalis set domain proteins, putative 0.0252 0.0719 0.4325
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0057 0.0342
Schistosoma mansoni microtubule-associated protein tau 0.2058 0.6235 0.6235
Schistosoma mansoni ap endonuclease 0.0057 0.0124 0.0124
Trichomonas vaginalis diacylglycerol kinase, putative 0.0074 0.0175 0.1053
Schistosoma mansoni ap endonuclease 0.0057 0.0124 0.0124
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0287 0.0825 0.0825
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Brugia malayi hypothetical protein 0.0074 0.0175 0.0645
Echinococcus multilocularis expressed protein 0.0035 0.0057 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0261 0.0952
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0181 0.3273
Loa Loa (eye worm) MH2 domain-containing protein 0.0247 0.0706 0.1235
Brugia malayi Pre-SET motif family protein 0.0222 0.0628 0.2313
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.01 0.0255 0.3542
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0095 0.057
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0168 0.0617
Schistosoma mansoni smad1 5 8 and 0.0017 0.0002 0.0002
Echinococcus multilocularis sodium:hydrogen exchanger 7 0.0019 0.0009 0.0009
Brugia malayi Eye-specific diacylglycerol kinase 0.0074 0.0175 0.0645
Trichomonas vaginalis diacylglycerol kinase, putative 0.0074 0.0175 0.1053
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.003 0.0611
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0053 0.0053
Echinococcus multilocularis Niemann Pick C1 protein 0.0191 0.0533 0.0533
Brugia malayi hypothetical protein 0.0036 0.0061 0.0223
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0044 0.0086 0.0314
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0128 0.0342 0.1251
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0491 0.1451 0.1451
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0139 0.0139
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0054 0.0199
Brugia malayi nuclear receptor NHR-67 0.0033 0.0053 0.0194
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0071 0.0167 0.0167
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0124 0.0124
Brugia malayi hypothetical protein 0.0033 0.0053 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.011 0.0664
Echinococcus granulosus heat shock protein 90 0.0026 0.003 0.003
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0042 0.0308
Schistosoma mansoni smad1 5 8 and 0.0017 0.0002 0.0002
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0047 0.0094 0.1912
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0044 0.0086 0.0086
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0141 0.0247
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0197 0.0719
Brugia malayi hypothetical protein 0.0242 0.069 0.2541
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.0019 0.0009 0.0032
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0139 0.0508
Loa Loa (eye worm) glutaminase 2 0.0561 0.1663 0.291
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0009
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0102 0.0261 0.1569
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0051 0.0183
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0021 0.0073
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0072 0.0267
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0255
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0026 0.0029 0.0029
Echinococcus granulosus phd:f box containing protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0071 0.0167 0.0292
Loa Loa (eye worm) hypothetical protein 0.0054 0.0115 0.0202
Echinococcus multilocularis alkaline phosphatase 0.0169 0.0468 0.0468
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0168 0.0279
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0161 0.0587
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Schistosoma mansoni phosphoglycerate kinase 0.0177 0.0492 0.0492
Schistosoma mansoni apoferritin-2 0.0027 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0074 0.0175 0.0306
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0038 0.0065 0.0114
Trichomonas vaginalis glutaminase, putative 0.0561 0.1663 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0044 0.0086 0.0314
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0228 0.04
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0021 0.0021
Trypanosoma brucei DNA polymerase IV, putative 0.0102 0.0261 0.0952
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0048 0.037
Loa Loa (eye worm) histone methyltransferase 0.0073 0.0172 0.0302
Loa Loa (eye worm) RecQ helicase 0.0047 0.0095 0.0166
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.01 0.0255 0.0255
Brugia malayi ecdysteroid receptor 0.0071 0.0167 0.0615
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Schistosoma mansoni hypothetical protein 0.0021 0.0016 0.0016
Plasmodium vivax sodium/hydrogen exchanger 1, putative 0.0019 0.0009 0.0176
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0053 0.0732
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0261 0.0952
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0291 0.0508
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0228 0.0228
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.01 0.0255 0.3542
Echinococcus multilocularis heat shock protein 0.0033 0.0051 0.0051
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0141 0.0141
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0057 0.0209
Loa Loa (eye worm) hypothetical protein 0.004 0.0072 0.0127
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0053 0.0053
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0124 0.1086
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0074 0.0175 0.0641
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.0115 0.0115
Schistosoma mansoni transcription factor LCR-F1 0.0185 0.0514 0.0514
Brugia malayi conserved hypotetical protein 0.0033 0.0053 0.0194
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0071 0.0167 0.0167
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0129 0.0129
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0001 0.0006
Trichomonas vaginalis endoplasmin, putative 0.002 0.0012 0.0073
Plasmodium falciparum T-complex protein 1 subunit beta 0.0026 0.0029 0.0581
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0053 0.0092
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0048 0.0984
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0141 0.0141
Brugia malayi ImpB/MucB/SamB family protein 0.0074 0.0176 0.0649
Leishmania major hypothetical protein, conserved 0.0044 0.0086 0.0314
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0042 0.0324
Mycobacterium ulcerans DNA polymerase IV 0.0102 0.0261 0.0442
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0053 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0021 0.0076
Entamoeba histolytica hypothetical protein 0.0029 0.004 0.007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0287 0.0825 0.0825
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0103 0.1436
Brugia malayi Calcitonin receptor-like protein seb-1 0.0906 0.2715 1
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0044 0.0086 0.0314
Schistosoma mansoni thyroid hormone receptor 0.0071 0.0167 0.0167
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0053 0.0053
Brugia malayi jmjC domain containing protein 0.0016 0.0001 0.0003
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0014 0.0052
Trypanosoma brucei heat shock protein, putative 0.0033 0.0051 0.0183
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.01 0.0255 0.0255
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0053 0.0053
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0364 0.1061 0.1061
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0071 0.0167 0.0167
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0059
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0014 0.001
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0291 0.1747
Echinococcus multilocularis Niemann Pick C1 protein 0.0273 0.0783 0.0783
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0177 0.0492 0.3757
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.1743
Loa Loa (eye worm) hypothetical protein 0.0061 0.0138 0.0241
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0065 0.1324
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0169 0.0468 0.0468
Mycobacterium ulcerans glutaminase 0.0561 0.1663 0.2899
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0292
Loa Loa (eye worm) hypothetical protein 0.0038 0.0065 0.0114
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0014 0.0016
Loa Loa (eye worm) diacylglycerol kinase 2 0.0074 0.0175 0.0306
Schistosoma mansoni diacylglycerol kinase theta 0.0074 0.0175 0.0175
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3186 0.9678 0.9678
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0044 0.0086 0.0516
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0124 0.0124
Giardia lamblia DNA damage repair protein 0.0023 0.0021 0.01
Brugia malayi jmjC domain containing protein 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0114
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.003 0.0452
Echinococcus multilocularis tumor protein p63 0.0328 0.0952 0.0952
Echinococcus multilocularis sodium:hydrogen exchanger 0.01 0.0255 0.0255
Plasmodium falciparum phosphoglycerate kinase 0.0177 0.0492 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0111 0.0195
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0168 0.0293
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0261 0.0954
Echinococcus granulosus tumor protein p63 0.0328 0.0952 0.0952
Schistosoma mansoni ferritin 0.0027 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0057 0.0124 0.0218
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0014 0.0053
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0059
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.001 0.0206
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0044 0.0086 0.0314
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0047 0.0094 0.0165
Loa Loa (eye worm) hypothetical protein 0.0364 0.1061 0.1856
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0053 0.0194
Echinococcus granulosus phosphoglycerate kinase 1 0.0177 0.0492 0.0492
Onchocerca volvulus Bile acid receptor homolog 0.0071 0.0167 0.232
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.011 0.0664
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0906 0.2715 0.475
Plasmodium vivax phosphoglycerate kinase, putative 0.0177 0.0492 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.004 0.0142
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0047 0.0094 0.1912
Brugia malayi ImpB/MucB/SamB family protein 0.01 0.0257 0.0948
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0048 0.0048
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0037 0.0063 0.0063
Echinococcus granulosus dnaJ subfamily C 6 0.0061 0.0137 0.0137
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0291 0.0494
Trypanosoma cruzi Na/H antiporter-like protein, putative 0.0019 0.0009 0.0032
Onchocerca volvulus 0.0252 0.0719 1
Leishmania major mitochondrial DNA polymerase beta 0.0912 0.2734 1
Treponema pallidum phosphoglycerate kinase 0.0177 0.0492 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0001 0.0001
Schistosoma mansoni heat shock protein 0.0033 0.0051 0.0051
Brugia malayi jmjC domain containing protein 0.0016 0.0001 0.0003
Echinococcus granulosus mixed lineage leukemia protein mll 0.0059 0.0129 0.0129
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0291 0.1747
Schistosoma mansoni hypothetical protein 0.0079 0.0191 0.0191
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0128 0.0342 0.1251
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0072 0.0072
Plasmodium vivax diacylglycerol kinase, putative 0.0074 0.0175 0.3561
Brugia malayi N-terminal motif family protein 0.018 0.0499 0.1838
Schistosoma mansoni sphingosine kinase A B 0.1889 0.5716 0.5716
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0042 0.0318
Trypanosoma brucei diacylglycerol kinase, putative 0.0074 0.0175 0.0638
Schistosoma mansoni RAR-like nuclear receptor 0.0071 0.0167 0.0167
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0124 0.0452
Echinococcus multilocularis neuropeptide receptor A26 0.0941 0.2824 0.2824
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.011 0.0664
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0074 0.0176 0.0176
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0014 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0168 0.0613
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0181 0.0181
Echinococcus multilocularis sphingosine kinase 1 0.1889 0.5716 0.5716
Toxoplasma gondii hypothetical protein 0.0147 0.0399 0.3051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Schistosoma mansoni ferritin 0.0027 0.0032 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0061 0.0061
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0311
Plasmodium falciparum diacylglycerol kinase, putative 0.0074 0.0175 0.3561
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0001 0.0006
Toxoplasma gondii hypothetical protein 0.0026 0.003 0.023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0169 0.0468 0.0468
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0161 0.0587
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0042 0.0863
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0042 0.0863
Loa Loa (eye worm) PDE1B protein 0.0044 0.0086 0.015
Schistosoma mansoni endoplasmin 0.0033 0.0051 0.0051
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0167 0.0167
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0104 0.0172
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0071 0.0167 0.0292
Brugia malayi tailless protein 0.0033 0.0053 0.0194
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0128 0.0342 0.1251
Onchocerca volvulus 0.0038 0.0065 0.0905
Schistosoma mansoni diacylglycerol kinase theta 0.0074 0.0175 0.0175
Schistosoma mansoni myst-related protein 0.0029 0.004 0.004
Leishmania major DNA polymerase kappa, putative 0.0081 0.0197 0.0722
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0111 0.0195
Schistosoma mansoni patched 1 0.0082 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0177 0.0492 0.0861
Echinococcus granulosus ferritin 0.0027 0.0032 0.0032
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0073 0.0172 0.0172
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.003 0.0452
Schistosoma mansoni hypothetical protein 0.0311 0.09 0.09
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Trypanosoma brucei heat shock protein, putative 0.0033 0.0051 0.0183
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.0032 0.004
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0021 0.0073
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0053 0.0053
Leishmania major sphingosine kinase A, B, putative 0.0074 0.0175 0.0641
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0071 0.0168 0.0293
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Entamoeba histolytica sodium/proton antiporter, putative 0.0019 0.0009 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0071 0.0167 0.0615
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.001 0.001
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0095 0.057
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0074 0.0175 0.0641
Loa Loa (eye worm) RNA binding protein 0.0062 0.0141 0.0247
Loa Loa (eye worm) hypothetical protein 0.0044 0.0086 0.015
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.0115 0.0115
Echinococcus multilocularis smad 0.0017 0.0002 0.0002
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0081 0.0197 0.0722
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0168 0.329
Brugia malayi nuclear receptor RXR 0.0033 0.0053 0.0194
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0222 0.0628 0.1099
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0261 0.0954
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0071 0.0167 0.0292
Mycobacterium ulcerans hypothetical protein 0.0023 0.0021 0.0021
Mycobacterium tuberculosis Conserved hypothetical protein 0.0074 0.0176 0.0299
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0053 0.0194
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0081 0.0197 0.0336
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.0662 0.0662
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0065 0.0235
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0016 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0073 0.0127
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0048 0.0075
Brugia malayi Smad1 0.0017 0.0002 0.0008
Echinococcus granulosus Niemann Pick C1 protein 0.0273 0.0783 0.0783
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0086 0.0311
Mycobacterium tuberculosis Conserved protein 0.0038 0.0065 0.0104
Echinococcus multilocularis endoplasmin 0.0026 0.003 0.003
Echinococcus multilocularis snurportin 1 0.0311 0.09 0.09
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0053 0.0053
Echinococcus granulosus FTZ F1 alpha 0.0071 0.0167 0.0167
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0028 0.0166
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0141 0.0141
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Brugia malayi photoreceptor-specific nuclear receptor 0.0071 0.0167 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.011 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.011 0.0664
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0319 0.0926 0.3409
Brugia malayi hypothetical protein 0.0037 0.0065 0.0239
Toxoplasma gondii TIM10 family protein, putative 0.0047 0.0094 0.0718
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0074 0.0175 0.1338
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0167 0.0615
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0086 0.0314
Echinococcus granulosus lamin dm0 0.0053 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0044
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0042 0.0074
Schistosoma mansoni hypothetical protein 0.0079 0.0191 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0261 0.0952
Plasmodium vivax heat shock protein 86, putative 0.0033 0.0051 0.1034
Brugia malayi hypothetical protein 0.0233 0.0662 0.244
Trypanosoma cruzi diacylglycerol kinase, putative 0.0074 0.0175 0.0641
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.0047 0.0047
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0061 0.0466
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.004 0.0072 0.0553
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0139 0.0508
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0018 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0167 0.0615
Echinococcus multilocularis geminin 0.0512 0.1514 0.1514
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0073 0.0172 0.0172
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0044 0.0086 0.0086
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Echinococcus granulosus ceramide kinase 0.0074 0.0175 0.0175
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0111 0.0195
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0168 0.0293
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0161 0.0587
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0014 0.0016
Echinococcus multilocularis GPCR, family 2 0.0287 0.0825 0.0825
Onchocerca volvulus Sodium\/hydrogen exchanger homolog 0.01 0.0255 0.3542
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0065 0.0238
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0014 0.0109
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0037 0.0064
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0091 0.0699
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0014 0.0109
Schistosoma mansoni hypothetical protein 0.0088 0.0219 0.0219
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0086 0.0086
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0016 0.0327
Trypanosoma brucei heat shock protein, putative 0.0033 0.0051 0.0183
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0014 0.0049
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Onchocerca volvulus Huntingtin homolog 0.0242 0.069 0.9589
Onchocerca volvulus Ceramide kinase 1 homolog 0.0074 0.0175 0.2435
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0104 0.0172
Schistosoma mansoni ferritin light chain 0.0027 0.0032 0.0032
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0103 0.0103
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0042 0.0863
Schistosoma mansoni nuclear receptor 0.0033 0.0053 0.0053
Mycobacterium tuberculosis Probable conserved integral membrane transport protein YjcE 0.0019 0.0009 0.0006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0037 0.0065 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0168 0.0279
Echinococcus granulosus heat shock protein 90 0.0033 0.0051 0.0051
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0044 0.0086 0.0086
Brugia malayi polk-prov protein 0.0051 0.0105 0.0388
Echinococcus granulosus sodium:hydrogen exchanger 2 nhe2 0.01 0.0255 0.0255
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0025 0.0091
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0025
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.018 0.0499 0.6938
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0261 0.0952
Treponema pallidum heat shock protein 90 0.0026 0.003 0.0008
Loa Loa (eye worm) hypothetical protein 0.005 0.0103 0.0181
Echinococcus multilocularis FTZ F1 alpha 0.0071 0.0167 0.0167
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0027 0.0032 0.0478
Echinococcus granulosus lysine specific demethylase 5A 0.0077 0.0185 0.0185
Mycobacterium ulcerans hypothetical protein 0.0038 0.0065 0.0099
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.004 0.0302
Brugia malayi mbt repeat family protein 0.005 0.0103 0.038
Brugia malayi Niemann-Pick C1 protein precursor 0.0191 0.0533 0.1962
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0037 0.0065 0.0065
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0025 0.0088
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0074 0.0175 0.0175
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0044 0.0086 0.0311
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0044 0.0086 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0261 0.0952
Onchocerca volvulus 0.0021 0.0014 0.0199
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0431 0.1268 0.4638
Loa Loa (eye worm) hypothetical protein 0.0025 0.0028 0.0049
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0073 0.0127
Schistosoma mansoni cpg binding protein 0.0231 0.0656 0.0656
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0065 0.0104
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0065 0.0392
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0051 0.0089
Toxoplasma gondii diacylglycerol kinase, putative 0.0074 0.0175 0.1338
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0065 0.0099
Brugia malayi sodium/hydrogen exchanger 3 family protein 0.01 0.0255 0.0939
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0044 0.0086 0.0314
Brugia malayi Bromodomain containing protein 0.0044 0.0084 0.0308
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0048 0.0048
Trypanosoma brucei unspecified product 0.0051 0.0106 0.0386
Brugia malayi MH1 domain containing protein 0.0017 0.0002 0.0008
Brugia malayi T-complex protein 1, beta subunit 0.0026 0.0029 0.0105
Brugia malayi jmjC domain containing protein 0.0016 0.0001 0.0003
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0103 0.0181
Loa Loa (eye worm) hypothetical protein 0.0242 0.069 0.1207
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0005 0.0005
Echinococcus multilocularis ceramide kinase 0.0074 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0292
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0077 0.1572
Toxoplasma gondii Na+/H+ exchanger NHE3 0.0019 0.0009 0.0066
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0291 0.0508
Onchocerca volvulus 0.0071 0.0167 0.232
Leishmania major DNA damage repair protein, putative 0.0023 0.0021 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Brugia malayi diacylglycerol kinase 0.0074 0.0175 0.0645
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Schistosoma mansoni glutaminase 0.0561 0.1663 0.1663
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0074 0.0175 0.1053
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0102 0.0169
Entamoeba histolytica hypothetical protein, conserved 0.1889 0.5716 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0014 0.0016
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0014 0.0118
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0002 0.0002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0028 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.011 0.0664
Echinococcus granulosus Niemann Pick C1 protein 0.0191 0.0533 0.0533
Echinococcus multilocularis Smad4 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.01 0.0257 0.0449
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0209 0.0587 0.0587
Giardia lamblia Grp94/Hsp90 0.0026 0.003 0.0193
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0124 0.0208
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0044 0.0086 0.0086
Echinococcus granulosus alkaline phosphatase 0.0169 0.0468 0.0468
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0168 0.0279
Schistosoma mansoni intermediate filament proteins 0.0053 0.0111 0.0111
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0044 0.0086 0.1743
Trichomonas vaginalis heat shock protein, putative 0.0026 0.003 0.0183
Leishmania major hypothetical protein, conserved 0.0024 0.0025 0.0091
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.011 0.0664
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.011 0.0664
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0048 0.0085
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0065 0.0239
Echinococcus granulosus transcription factor Dp 1 0.004 0.0072 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0065 0.0239
Mycobacterium ulcerans hypothetical protein 0.0071 0.0168 0.0279
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0115 0.0115
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.0122 0.0448
Onchocerca volvulus 0.0231 0.0656 0.9121
Brugia malayi glutaminase DH11.1 0.0561 0.1663 0.6126
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0028 0.0048
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0044 0.0086 0.0316
Entamoeba histolytica sodium/proton antiporter, putative 0.0019 0.0009 0.0015
Mycobacterium ulcerans diacylglycerol kinase 0.0074 0.0175 0.0292
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0071 0.0167 0.0167
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0167 0.0167
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0056
Toxoplasma gondii histone lysine methyltransferase SET1 0.0445 0.131 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0181 0.0181
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.1743
Entamoeba histolytica Ran family GTPase 0.0021 0.0016 0.0028
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0431 0.1268 0.4638
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0044 0.0086 0.0086
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0051 0.0186
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0319 0.0926 0.0926
Loa Loa (eye worm) heat shock protein 90 0.0033 0.0051 0.0089
Brugia malayi MH2 domain containing protein 0.0247 0.0706 0.26
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0124 0.0458
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0014 0.001
Trypanosoma brucei unspecified product 0.0095 0.024 0.0875
Schistosoma mansoni phosphoglycerate kinase 0.0177 0.0492 0.0492
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0014 0.001
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0065 0.0149 0.0546
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0197
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0037 0.0065 0.0065
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0044 0.0086 0.0516
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.011 0.0664
Brugia malayi hypothetical protein 0.0037 0.0065 0.0239
Entamoeba histolytica diacylglycerol kinase, putative 0.0074 0.0175 0.0306
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0048 0.0177
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0028 0.0101
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0255
Brugia malayi RNA binding protein 0.0062 0.0141 0.0519
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0014 0.0052
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0053 0.0053
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0053 0.0092
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0071 0.0167 0.0167
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0128 0.0342 0.1248
Trypanosoma cruzi Heat shock protein 83, putative 0.0033 0.0051 0.0186
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0014 0.001
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0051 0.0186
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0086 0.0314
Schistosoma mansoni DNA helicase recq1 0.002 0.001 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0168 0.0279
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0074 0.0175 0.0641
Brugia malayi Probable ClpP-like protease 0.0076 0.0181 0.0668
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0113 0.0188
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0261 0.0954
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0139 0.0139
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0167 0.0167
Echinococcus granulosus lamin 0.0053 0.0111 0.0111
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.003 0.0111
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0014 0.0016
Plasmodium vivax endoplasmin, putative 0.0033 0.0051 0.1034
Onchocerca volvulus 0.0038 0.0065 0.0905
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.011 0.0664
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0111 0.041
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0071 0.0167 0.0615
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0014 0.001
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0168 0.0617
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0048 0.037
Mycobacterium tuberculosis Conserved protein 0.1889 0.5716 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0065 0.0065
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0047 0.0094 0.0718
Trichomonas vaginalis heat shock protein, putative 0.002 0.0012 0.0073
Loa Loa (eye worm) hypothetical protein 0.018 0.0499 0.0873
Echinococcus granulosus ecdysone induced protein 78C 0.0071 0.0167 0.0167
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0124 0.0124
Brugia malayi TAR-binding protein 0.0062 0.0141 0.0519
Entamoeba histolytica deoxycytidyl transferase, putative 0.0074 0.0176 0.0308
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0168 0.329
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Leishmania major DNA polymerase eta, putative 0.0049 0.0102 0.0372
Schistosoma mansoni hypothetical protein 0.0512 0.1514 0.1514
Mycobacterium ulcerans heat shock protein 90 0.0026 0.003 0.0038
Loa Loa (eye worm) hypothetical protein 0.01 0.0255 0.0446
Schistosoma mansoni hypothetical protein 0.0185 0.0514 0.0514
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.011 0.0664
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0103 0.0103
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.001 0.001
Trichomonas vaginalis sphingosine kinase, putative 0.0074 0.0175 0.1053
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0114
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0014 0.0291
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0141 0.0519
Mycobacterium tuberculosis Conserved protein 0.0038 0.0065 0.0104
Schistosoma mansoni smad1 5 8 and 0.0017 0.0002 0.0002
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0053 0.0053
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0124 0.0203
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0228 0.0841
Plasmodium vivax phosphodiesterase gamma, putative 0.0044 0.0086 0.1743
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0169 0.0468 0.0468
Toxoplasma gondii heat shock protein HSP90 0.0033 0.0051 0.0389
Brugia malayi DnaJ domain containing protein 0.0061 0.0137 0.0504
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0053 0.0053
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0291 0.1063
Brugia malayi diacylglycerol kinase 0.0074 0.0175 0.0645
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Echinococcus granulosus dna polymerase kappa 0.0102 0.0261 0.0261
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0044 0.0086 0.0086
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0161 0.0161
Mycobacterium ulcerans hypothetical protein 0.1889 0.5716 1
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0044 0.0086 0.0086
Echinococcus multilocularis protein dispatched 1 0.0093 0.0236 0.0236
Echinococcus multilocularis heat shock protein 90 0.0033 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0292
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0181 0.0302
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0074 0.0175 0.0306
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0065 0.0149 0.0546
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0065 0.0065
Echinococcus granulosus importin subunit beta 1 0.0029 0.004 0.004
Entamoeba histolytica diacylglycerol kinase, putative 0.0074 0.0175 0.0306
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0074 0.0175 0.0175
Mycobacterium ulcerans DNA polymerase IV 0.0102 0.0261 0.0442
Plasmodium falciparum endoplasmin, putative 0.002 0.0012 0.0246
Plasmodium falciparum phosphodiesterase delta, putative 0.0044 0.0086 0.1743
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0127 0.0463
Loa Loa (eye worm) hypothetical protein 0.0048 0.0097 0.017
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.011 0.0664
Loa Loa (eye worm) hypothetical protein 0.0038 0.0065 0.0114
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0009
Echinococcus multilocularis zinc finger protein 0.0037 0.0064 0.0064
Schistosoma mansoni survival motor neuron protein 0.0048 0.0096 0.0096
Leishmania major phosphoglycerate kinase B, cytosolic 0.0177 0.0492 0.18
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0364 0.1061 0.1061
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0014 0.0053
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0048 0.0178
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0014 0.0049
Trypanosoma cruzi Sphingosine kinase 0.0074 0.0175 0.0641
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0059 0.0129 0.0129
Onchocerca volvulus 0.0036 0.0061 0.0848
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0364 0.1061 0.8101
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0071 0.0167 0.0615
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0037 0.0065 0.0065
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0071 0.0167 0.232
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0064 0.0064
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0074 0.0175 0.0638
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0053 0.0194
Trypanosoma brucei heat shock protein, putative 0.0033 0.0051 0.0183
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0054 0.0196
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0014 0.001
Onchocerca volvulus 0.0053 0.0111 0.1547
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.0662 0.0662
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0074 0.0175 0.1338
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0292
Schistosoma mansoni endoplasmin 0.0033 0.0051 0.0051
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0102 0.1928
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0014 0.0014
Schistosoma mansoni zinc finger protein 0.0033 0.0053 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0228 0.0228
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0364 0.1061 0.1061
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0095 0.0349
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0071 0.0167 0.0615
Echinococcus multilocularis thyroid hormone receptor alpha 0.0071 0.0167 0.0167
Brugia malayi MH2 domain containing protein 0.0017 0.0002 0.0008
Trypanosoma cruzi Sphingosine kinase 0.0074 0.0175 0.0641
Echinococcus granulosus mitochondrial sodium:hydrogen exchanger 9B2 0.0019 0.0009 0.0009
Echinococcus granulosus snurportin 1 0.0311 0.09 0.09
Loa Loa (eye worm) beta-lactamase 0.0038 0.0065 0.0114
Mycobacterium tuberculosis Conserved protein 0.0038 0.0065 0.0104
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0014 0.001
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0028
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0065 0.0065
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0071 0.0167 0.0167
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0042 0.0324
Trichomonas vaginalis DNA polymerase eta, putative 0.0102 0.0261 0.1569
Leishmania major diacylglycerol kinase-like protein 0.0074 0.0175 0.0641
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0071 0.0167 0.0167
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0113 0.0182
Echinococcus multilocularis dna polymerase kappa 0.0102 0.0261 0.0261
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.1743
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0053 0.0053
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.0032 0.0478
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0014 0.0053
Brugia malayi jmjC domain containing protein 0.0077 0.0185 0.0682
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0168 0.0284
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0141 0.0247
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0042 0.0268
Toxoplasma gondii t-complex protein beta subunit 0.0026 0.0029 0.0218
Loa Loa (eye worm) steroid hormone receptor 0.0071 0.0167 0.0292
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0412 0.1516
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0168 0.0613
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0181 0.3088
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0048 0.0177
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0191 0.0533 0.0932
Leishmania major hypothetical protein, conserved 0.0074 0.0175 0.0641
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0102 0.0102
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0065 0.0149 0.0546
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Echinococcus multilocularis neuropeptide s receptor 0.0941 0.2824 0.2824
Entamoeba histolytica phosphoglycerate kinase, putative 0.0177 0.0492 0.0861
Brugia malayi nuclear hormone receptor 0.0071 0.0167 0.0615
Brugia malayi Phosphoglycerate kinase 0.0177 0.0492 0.1812
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0167 0.0167
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0065 0.0238
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0261 0.0952
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0912 0.2734 1
Trypanosoma brucei Heat shock protein 83, putative 0.0033 0.0051 0.0183
Mycobacterium tuberculosis Conserved hypothetical protein 0.048 0.1417 0.2471
Leishmania major Na/H antiporter-like protein 0.0019 0.0009 0.0032
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0287 0.0825 0.0825
Brugia malayi hypothetical protein 0.0185 0.0514 0.1893
Loa Loa (eye worm) CXXC zinc finger family protein 0.0231 0.0656 0.1148
Schistosoma mansoni hypothetical protein 0.0287 0.0825 0.0825
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0161 0.0161
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0115 0.0115
Echinococcus multilocularis protein patched 0.0082 0.02 0.02
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0071 0.0168 0.0293
Giardia lamblia Hypothetical protein 0.0044 0.0086 0.072
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.003 0.0193
Echinococcus granulosus sodium:hydrogen exchanger 2 (nhe2) 0.0081 0.0197 0.0197
Schistosoma mansoni hypothetical protein 0.0079 0.0191 0.0191
Brugia malayi nuclear receptor RXR 0.0037 0.0065 0.0239
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0053 0.0194
Echinococcus granulosus sodium:hydrogen exchanger 0.01 0.0255 0.0255
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Onchocerca volvulus Protein ultraspiracle homolog 0.0071 0.0167 0.232
Trypanosoma brucei unspecified product 0.0051 0.0106 0.0386
Schistosoma mansoni hypothetical protein 0.0287 0.0825 0.0825
Echinococcus multilocularis sodium:hydrogen exchanger 2 (nhe2) 0.01 0.0255 0.0255
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0168 0.0279
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0065 0.1169
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0044 0.0086 0.0086
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0169 0.0468 0.0468
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0114
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0044 0.0086 0.0086
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0014 0.0086
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0059
Loa Loa (eye worm) ceramide kinase 0.0074 0.0175 0.0306
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0001 0.0001
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0026 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0079 0.0191 0.0191
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0072 0.0267
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0014 0.0291
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0072 0.0267
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.0032 0.0036
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0021 0.0158
Echinococcus granulosus neuropeptide s receptor 0.0941 0.2824 0.2824
Loa Loa (eye worm) sodium/hydrogen exchanger 0.01 0.0255 0.0446
Onchocerca volvulus 0.0048 0.0096 0.1332
Brugia malayi beta-lactamase 0.0038 0.0065 0.024
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.0032 0.004
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.001 0.0018
Brugia malayi beta-lactamase family protein 0.0038 0.0065 0.024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0291 0.1063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0025 0.0149
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0292
Mycobacterium ulcerans beta-lactamase 0.0038 0.0065 0.0099
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0074 0.0175 0.0306
Echinococcus granulosus geminin 0.0512 0.1514 0.1514
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0086 0.0086
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Possible penicillin-binding protein 0.024 0.0682 0.1185
Schistosoma mansoni Smad4 0.0017 0.0002 0.0002
Echinococcus granulosus dna polymerase eta 0.01 0.0257 0.0257
Brugia malayi hypothetical protein 0.0024 0.0025 0.0092
Schistosoma mansoni ferritin 0.0027 0.0032 0.0032
Onchocerca volvulus 0.0033 0.0053 0.0732
Trypanosoma brucei phosphoglycerate kinase 0.0177 0.0492 0.1797
Schistosoma mansoni DNA polymerase eta 0.01 0.0257 0.0257
Schistosoma mansoni hypothetical protein 0.0061 0.0137 0.0137
Trypanosoma cruzi sodium/hydrogen exchanger, putative 0.0019 0.0009 0.0032
Echinococcus granulosus sphingosine kinase 1 0.1889 0.5716 0.5716
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0044 0.0086 0.0314
Trichomonas vaginalis ran, putative 0.0021 0.0016 0.0097
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0036 0.0219
Loa Loa (eye worm) T-complex protein 1 0.0026 0.0029 0.005
Brugia malayi 6-phosphofructokinase 0.0111 0.0291 0.107
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0194 0.0542 0.0542
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0026 0.0029 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0287 0.0825 0.0825
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Schistosoma mansoni hypothetical protein 0.0287 0.0825 0.0825
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0181 0.0302
Trypanosoma brucei DNA polymerase IV, putative 0.0102 0.0261 0.0952
Loa Loa (eye worm) glutaminase 0.0561 0.1663 0.291
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0255
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Echinococcus multilocularis heat shock protein 90 0.0026 0.003 0.003
Schistosoma mansoni apoferritin-2 0.0027 0.0032 0.0032
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0014 0.0118
Echinococcus granulosus expressed protein 0.0035 0.0057 0.0057
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0071 0.0167 0.0167
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0906 0.2715 0.475
Mycobacterium ulcerans phosphoglycerate kinase 0.0177 0.0492 0.0847
Brugia malayi 6-phosphofructokinase 0.0111 0.0291 0.107
Schistosoma mansoni myst-related protein 0.0029 0.004 0.004
Leishmania major hypothetical protein, conserved 0.0044 0.0086 0.0314
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.001 0.001
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0124 0.0747
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0287 0.0825 0.304
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0044 0.0086 0.0086
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0065 0.0149 0.0546
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.0053 0.0092
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0049 0.0102 0.0777
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Echinococcus granulosus bloom syndrome protein 0.0047 0.0095 0.0095
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0054 0.0199
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0071 0.0167 0.0167
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0072 0.1471
Mycobacterium tuberculosis Diacylglycerol kinase 0.0074 0.0175 0.0297
Onchocerca volvulus 0.0053 0.0111 0.1547
Brugia malayi Bromodomain containing protein 0.0095 0.0241 0.0886
Toxoplasma gondii exonuclease III APE 0.0057 0.0124 0.0949
Plasmodium falciparum importin beta, putative 0.0029 0.004 0.0804
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0181 0.0181
Echinococcus multilocularis lamin 0.0053 0.0111 0.0111
Trichomonas vaginalis bmru protein, putative 0.0074 0.0175 0.1053
Onchocerca volvulus Huntingtin homolog 0.0242 0.069 0.9589
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0168 0.0613
Echinococcus multilocularis Diacylglycerol kinase theta 0.0074 0.0175 0.0175
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0095 0.0095
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0071 0.0167 0.0167
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0065 0.0392
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.001 0.0037
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0141 0.0141
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0168 0.0279
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0103 0.0103
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0044
Leishmania major cAMP-specific phosphodiesterase, putative 0.0044 0.0086 0.0314
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.0428 0.1564
Giardia lamblia TCP-1 chaperonin subunit beta 0.0026 0.0029 0.0176
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0044 0.0086 0.0311
Leishmania major diacylglycerol kinase, putative 0.0074 0.0175 0.0641
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.011 0.0664
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0025 0.0091
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0177 0.0492 0.3757
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0025 0.0507
Schistosoma mansoni cpg binding protein 0.0246 0.0703 0.0703
Entamoeba histolytica hypothetical protein 0.0185 0.0514 0.0899
Echinococcus multilocularis dna polymerase eta 0.01 0.0257 0.0257
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0124 0.2039
Entamoeba histolytica hypothetical protein 0.0185 0.0514 0.0899
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0028 0.0098
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0291 0.0291
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0124 0.0217
Schistosoma mansoni zinc finger protein 0.0037 0.0064 0.0064
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0291 0.1061
Loa Loa (eye worm) hypothetical protein 0.0076 0.0181 0.0317
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0014 0.0052
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0071 0.0167 0.0167
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0065 0.0065
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0014 0.001
Plasmodium falciparum diacylglycerol kinase, putative 0.0074 0.0175 0.3561
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0044 0.0086 0.0086
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0103 0.0103
Echinococcus multilocularis mitochondrial sodium:hydrogen exchanger 9B2 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0037 0.0065 0.0114
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0113 0.2293
Brugia malayi Endoplasmin precursor 0.0033 0.0051 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.02 0.1205
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0053 0.0053
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0065 0.0392
Trichomonas vaginalis chaperonin, putative 0.0026 0.0029 0.0172
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0053 0.0194
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0014 0.0014
Plasmodium vivax JmjC domain containing protein 0.0016 0.0001 0.0017
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0431 0.1268 0.4636
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0016 0.0016
Schistosoma mansoni bromodomain containing protein 0.0083 0.0203 0.0203
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0037 0.0065 0.0114
Plasmodium vivax diacylglycerol kinase, putative 0.0074 0.0175 0.3561
Echinococcus multilocularis expressed conserved protein 0.0179 0.0497 0.0497
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0169 0.0468 0.0468
Schistosoma mansoni DNA helicase recq5 0.002 0.001 0.001
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0053 0.0194
Loa Loa (eye worm) hypothetical protein 0.0287 0.0825 0.1444
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0319 0.0926 0.0926
Giardia lamblia Heat shock protein HSP 90-alpha 0.0033 0.0051 0.0388
Echinococcus granulosus Protein patched homolog 1 0.0082 0.02 0.02
Trypanosoma brucei phosphoglycerate kinase, putative 0.0065 0.0149 0.0543
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0044 0.0086 0.015
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0412 0.0412
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0065 0.0149 0.0546
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.0032 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0014 0.001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0023 0.0137
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Trypanosoma cruzi ISWI complex protein 0.0024 0.0025 0.009
Echinococcus granulosus heat shock protein 0.0033 0.0051 0.0051
Brugia malayi steroid hormone receptor 0.0071 0.0167 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0086 0.0516
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0044 0.0086 0.0314
Leishmania major hypothetical protein, conserved 0.0019 0.0009 0.0032
Loa Loa (eye worm) endoplasmin 0.0033 0.0051 0.0089
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0044 0.0086 0.0316
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0014 0.001
Echinococcus granulosus sterol regulatory element binding protein 0.0082 0.02 0.02
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0124 0.0124
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Brugia malayi mbt repeat family protein 0.005 0.0103 0.038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0168 0.0279
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0048 0.0978
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Echinococcus granulosus expressed conserved protein 0.0179 0.0497 0.0497
Brugia malayi SET domain containing protein 0.0021 0.0016 0.0058
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0096 0.0353
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0168 0.0284
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0074 0.0175 0.0175
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0026 0.0029 0.0029
Leishmania major cathepsin L-like protease 0.0062 0.0139 0.0508
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0167 0.0615
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0014 0.001
Brugia malayi RNA, U transporter 1 0.0083 0.0204 0.075
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0001 0.0017
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0021 0.0076
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0051 0.0186
Schistosoma mansoni lamin 0.0053 0.0111 0.0111
Leishmania major cathepsin L-like protease 0.0062 0.0139 0.0508
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0364 0.1061 0.1061
Entamoeba histolytica hypothetical protein 0.0185 0.0514 0.0899
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0001 0.0001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0311 0.09 0.1575
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0086 0.0314
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0014 0.0016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0124 0.0454
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0124 0.2392
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0161 0.0161
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0228 0.0228
Onchocerca volvulus 0.0019 0.0009 0.012
Schistosoma mansoni hypothetical protein 0.0048 0.0096 0.0096
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0065 0.0104
Schistosoma mansoni cpg binding protein 0.0246 0.0703 0.0703
Schistosoma mansoni hypothetical protein 0.0074 0.0175 0.0175
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.011 0.0664
Echinococcus multilocularis importin subunit beta 1 0.0029 0.004 0.004
Brugia malayi Importin beta-1 subunit 0.0029 0.004 0.0146
Leishmania major GTP-binding protein, putative 0.0021 0.0016 0.0059
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0082 0.02 0.0351
Loa Loa (eye worm) DR-78 0.0033 0.0053 0.0092
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0001 0.0001
Toxoplasma gondii ABC1 family protein 0.0038 0.0065 0.0497
Entamoeba histolytica hypothetical protein 0.0185 0.0514 0.0899
Loa Loa (eye worm) hypothetical protein 0.0046 0.0091 0.016
Schistosoma mansoni alkaline phosphatase 0.0169 0.0468 0.0468
Giardia lamblia hypothetical protein 0.0044 0.0086 0.072
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0161 0.0591
Schistosoma mansoni ferritin 0.0027 0.0032 0.0032
Plasmodium falciparum phosphodiesterase gamma, putative 0.0044 0.0086 0.1743
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0014 0.0025
Echinococcus granulosus intermediate filament protein 0.0053 0.0111 0.0111
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Brugia malayi T-complex protein 1, beta subunit 0.0026 0.0029 0.0105
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0124 0.2525
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0021 0.042
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Loa Loa (eye worm) transcription factor SMAD2 0.0247 0.0706 0.1235
Plasmodium vivax importin-beta 2, putative 0.0029 0.004 0.0804
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0071 0.0167 0.0615
Brugia malayi F/Y-rich N-terminus family protein 0.0074 0.0176 0.0647
Trypanosoma cruzi DNA polymerase eta, putative 0.01 0.0257 0.0941
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0261 0.0952
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Trichomonas vaginalis esterase, putative 0.0038 0.0065 0.0392
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0065 0.0065
Schistosoma mansoni sodium/hydrogen exchanger 3 (nhe3) 0.0019 0.0009 0.0009
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0177 0.0492 0.18
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0059 0.0129 0.0129
Echinococcus granulosus cpg binding protein 0.0246 0.0703 0.0703
Onchocerca volvulus 0.0025 0.0026 0.0367
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0001 0.0001
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0048 0.0984
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0044 0.0086 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0175 0.1053
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0912 0.2734 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0124 0.0124
Echinococcus multilocularis dnaJ subfamily C 6 0.0061 0.0137 0.0137
Leishmania major DNA polymerase eta, putative 0.01 0.0257 0.0941
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0065 0.0104
Plasmodium falciparum zinc finger protein, putative 0.0029 0.004 0.0812
Echinococcus multilocularis dnaJ subfamily B 0.3292 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0255
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.003 0.0444
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0124 0.0454
Schistosoma mansoni SET domain protein 0.0021 0.0016 0.0016
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0019 0.0009 0.0006
Giardia lamblia Phosphoglycerate kinase 0.0177 0.0492 0.4586
Trypanosoma brucei phosphoglycerate kinase 0.0065 0.0149 0.0543
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0113 0.1564
Loa Loa (eye worm) hypothetical protein 0.0144 0.0389 0.0681
Echinococcus granulosus sodium:hydrogen exchanger 0.01 0.0255 0.0255
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0014 0.001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0071 0.0167 0.0167
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0181 0.1384
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0181 0.3572
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.003 0.0044
Plasmodium falciparum heat shock protein 90 0.0033 0.0051 0.1034
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0051 0.0306
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.01 0.0255 0.0446
Schistosoma mansoni jumonji/arid domain-containing protein 0.0077 0.0185 0.0185
Leishmania major heat shock protein 83-1 0.0033 0.0051 0.0186
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0014 0.0052
Trypanosoma cruzi diacylglycerol kinase, putative 0.0074 0.0175 0.0641
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0177 0.0492 0.2958
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.011 0.0664
Loa Loa (eye worm) hypothetical protein 0.0044 0.0086 0.015
Loa Loa (eye worm) hypothetical protein 0.0071 0.0167 0.0292
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0047 0.0094 0.0346
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0072 0.1471
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0044 0.0086 0.0316
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0014 0.0025
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0044 0.0086 0.0316
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0124 0.0454
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0291 0.1747
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0291 0.1747
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0124 0.0217
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0291 0.5835
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Brugia malayi hypothetical protein 0.0033 0.0053 0.0194
Echinococcus granulosus expressed protein 0.0047 0.0094 0.0094
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0167 0.0615
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0044
Schistosoma mansoni Slc9a7 protein 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0177 0.0492 1
Echinococcus granulosus sodium:hydrogen exchanger 7 0.0019 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0086 0.0314
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0291 0.5641
Schistosoma mansoni heat shock protein 0.0033 0.0051 0.0051
Echinococcus multilocularis microtubule associated protein 2 0.2058 0.6235 0.6235
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.0105 0.0382
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0177 0.0492 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0014 0.0025
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0002 0.0002
Schistosoma mansoni terminal deoxycytidyl transferase 0.0074 0.0176 0.0176
Brugia malayi nuclear hormone receptor 0.0033 0.0053 0.0194
Echinococcus multilocularis cpg binding protein 0.0246 0.0703 0.0703
Loa Loa (eye worm) hypothetical protein 0.0052 0.0108 0.019
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0048 0.0177
Toxoplasma gondii sodium/hydrogen exchanger 3 protein 0.0019 0.0009 0.0066
Brugia malayi jmjC domain containing protein 0.0062 0.0139 0.0511
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0021 0.0073
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0103 0.0103
Toxoplasma gondii heat shock protein 90, putative 0.0033 0.0051 0.0389
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0113 0.2293
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0073 0.1481
Leishmania major T-complex protein 1, beta subunit, putative 0.0026 0.0029 0.0105
Schistosoma mansoni thyroid hormone receptor 0.0071 0.0167 0.0167
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0023 0.0137
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0181 0.3088
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0065 0.0104
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0005 0.0005
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0014 0.0118
Loa Loa (eye worm) hypothetical protein 0.0053 0.0113 0.0197
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0014 0.0016
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0044 0.0086 0.0516
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Brugia malayi Latrophilin receptor protein 2 0.0287 0.0825 0.304
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0074 0.0176 0.0308
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0079 0.0192 0.0192
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0102 0.0169
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0124 0.2525
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0086 0.0314
Leishmania major phosphoglycerate kinase C, glycosomal 0.0177 0.0492 0.18
Brugia malayi Steroid receptor seven-up type 2 0.0071 0.0167 0.0615
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.0516
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0168 0.0617
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.011 0.0664
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0053 0.0053
Leishmania major DNA polymerase kappa, putative 0.0023 0.0021 0.0076
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0014 0.0016
Schistosoma mansoni rotamase 0.0035 0.0057 0.0057
Brugia malayi isocitrate dehydrogenase 0.0032 0.0048 0.0178
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0364 0.1061 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0092
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0127 0.0463
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0065 0.0099
Schistosoma mansoni lamin 0.0053 0.0111 0.0111
Entamoeba histolytica diacylglycerol kinase, putative 0.0074 0.0175 0.0306
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0044 0.0086 0.0086
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0124 0.0458
Trypanosoma brucei ISWI complex protein 0.0024 0.0025 0.0087
Trichomonas vaginalis helicase, putative 0.0052 0.011 0.0664
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.011 0.0664
Echinococcus multilocularis expressed protein 0.0027 0.0032 0.0032
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.004 0.0072 0.0072
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0139 0.0508
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0291 0.0291
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0161 0.0585
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0124 0.0124
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0091 0.0699
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0053 0.0053
Leishmania major hypothetical protein, conserved 0.0074 0.0175 0.0641
Trypanosoma brucei heat shock protein, putative 0.0033 0.0051 0.0183
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0056
Loa Loa (eye worm) Smad1 0.0017 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0619 0.184 0.322
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0044 0.0086 0.1743
Onchocerca volvulus 0.0021 0.0016 0.022
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0091 0.0091
Mycobacterium ulcerans hypothetical protein 0.048 0.1417 0.2467
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0209 0.0587 0.0587
Giardia lamblia Sodium/hydrogen exchanger 3 0.01 0.0255 0.2329
Trichomonas vaginalis rotamase, putative 0.0034 0.0054 0.0327
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0025 0.0507
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0228 0.0228
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0071 0.0167 0.0167
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0055 0.0055
Onchocerca volvulus 0.0021 0.0014 0.0199
Toxoplasma gondii sodium/hydrogen exchanger NHE2 0.0019 0.0009 0.0066
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0048 0.0174
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0086 0.0655
Loa Loa (eye worm) hypothetical protein 0.0242 0.069 0.1207
Trypanosoma brucei heat shock protein, putative 0.0033 0.0051 0.0183
Schistosoma mansoni alkaline phosphatase 0.0169 0.0468 0.0468
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0054 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0139 0.0505
Echinococcus granulosus Smad4 0.0017 0.0002 0.0002

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.82 nM Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysis ChEMBL. 21724305

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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