Detailed information for compound 1634547

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 185.263 | Formula: C10H19NO2
  • H donors: 2 H acceptors: 2 LogP: 1.03 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCN1CC=C[C@@H]([C@@H]1CO)O
  • InChi: 1S/C10H19NO2/c1-2-3-6-11-7-4-5-10(13)9(11)8-12/h4-5,9-10,12-13H,2-3,6-8H2,1H3/t9-,10-/m0/s1
  • InChiKey: NHPSLFSVHQQWQU-UWVGGRQHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus UDP-glucose ceramide glucosyltransferase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Ceramide glucosyltransferase Get druggable targets OG5_129848 All targets in OG5_129848
Schistosoma japonicum ko:K00720 ceramide glucosyltransferase [EC2.4.1.80], putative Get druggable targets OG5_129848 All targets in OG5_129848
Schistosoma japonicum Ceramide glucosyltransferase, putative Get druggable targets OG5_129848 All targets in OG5_129848
Schistosoma mansoni ceramide glucosyltransferase Get druggable targets OG5_129848 All targets in OG5_129848
Onchocerca volvulus Ceramide glucosyltransferase homolog Get druggable targets OG5_129848 All targets in OG5_129848
Candida albicans ceramide glucosyltransferase Get druggable targets OG5_129848 All targets in OG5_129848
Loa Loa (eye worm) ceramide glucosyltransferase Get druggable targets OG5_129848 All targets in OG5_129848
Schistosoma mansoni ceramide glucosyltransferase Get druggable targets OG5_129848 All targets in OG5_129848
Candida albicans ceramide glucosyltransferase Get druggable targets OG5_129848 All targets in OG5_129848
Echinococcus granulosus ceramide glucosyltransferase Get druggable targets OG5_129848 All targets in OG5_129848
Echinococcus multilocularis ceramide glucosyltransferase Get druggable targets OG5_129848 All targets in OG5_129848
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi NIMA-related kinase, putative 0.0016 0.0014 0.0059
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Trypanosoma cruzi Protein kinase B 0.0016 0.0014 0.0059
Brugia malayi Sugar transporter family protein 0.0743 0.2394 0.2789
Schistosoma mansoni transcription factor LCR-F1 0.0061 0.0163 0.0159
Schistosoma mansoni protein kinase 0.0018 0.002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0045
Leishmania major protein kinase, putative 0.0016 0.0014 0.0017
Onchocerca volvulus Ceramide glucosyltransferase homolog 0.0288 0.0905 0.3766
Brugia malayi C1-like domain containing protein 0.0257 0.0804 0.0932
Trichomonas vaginalis AGC family protein kinase 0.0452 0.1443 0.6017
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0032 0.0065 0.0221
Schistosoma mansoni titin 0.002 0.0028 0.0023
Brugia malayi Protein kinase domain containing protein 0.0039 0.0089 0.0097
Echinococcus granulosus Sugar transporter ERD6 protein 0.0743 0.2394 0.239
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0018 0.002 0.0059
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0032 0.0065 0.0249
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0015 0.0012 0.0028
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0026 0.0046 0.014
Trypanosoma brucei protein kinase, putative 0.0016 0.0014 0.0059
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0257 0.0804 0.0798
Leishmania major DNA damage repair protein, putative 0.0015 0.0012 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0021 0.0016
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.004 0.0092 0.0363
Entamoeba histolytica protein kinase, putative 0.0016 0.0014 0.01
Trypanosoma brucei glucose transporter, putative 0.0743 0.2394 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0015 0.0012 0.0051
Loa Loa (eye worm) PHD-finger family protein 0.0018 0.002 0.0014
Echinococcus multilocularis serine:threonine protein kinase N2 0.0448 0.1429 0.1424
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0038 0.0088 0.0343
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0021 0.0018
Brugia malayi Protein kinase domain containing protein 0.0452 0.1443 0.1678
Trypanosoma cruzi NIMA-related kinase, putative 0.0016 0.0014 0.0059
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0075 0.0311
Trypanosoma brucei rac serine-threonine kinase, putative 0.0452 0.1443 0.6026
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.0021 0.0018
Giardia lamblia Kinase, CMGC CLK 0.0141 0.0423 0.0487
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0013 0.0006 0.0023
Schistosoma mansoni ceramide glucosyltransferase 0.0288 0.0905 0.0901
Loa Loa (eye worm) hypothetical protein 0.0113 0.0334 0.0328
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0045
Trichomonas vaginalis bromodomain-containing protein, putative 0.0038 0.0088 0.0343
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0423 0.0418
Leishmania major DNA polymerase kappa, putative 0.005 0.0125 0.0145
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0021 0.003 0.0025
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Brugia malayi Sugar transporter family protein 0.0743 0.2394 0.2789
Toxoplasma gondii hypothetical protein 0.0021 0.0031 0.0104
Echinococcus multilocularis unc 13 (munc13) 0.0027 0.0051 0.0045
Toxoplasma gondii HEAT repeat-containing protein 0.0015 0.0012 0.0026
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0115 0.0337 0.0332
Trypanosoma cruzi importin beta-1 subunit, putative 0.0065 0.0176 0.0733
Plasmodium vivax importin-beta 2, putative 0.0081 0.0226 0.0921
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0054 0.0138 0.016
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0066 0.0179 0.1238
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0045
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0141 0.0423 0.1765
Trypanosoma brucei ISWI complex protein 0.0013 0.0005 0.0019
Echinococcus multilocularis neuroglian 0.0025 0.0045 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0026 0.0046 0.0168
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0021 0.0031 0.0104
Brugia malayi RNA, U transporter 1 0.0229 0.0712 0.0824
Echinococcus granulosus Immunoglobulin 0.0017 0.0017 0.0011
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0061 0.0161 0.065
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0021 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0099 0.0287 0.1197
Mycobacterium ulcerans hypothetical protein 0.0099 0.0287 0.1153
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0099 0.0287 0.1153
Echinococcus multilocularis raf serine:threonine protein kinase 0.0033 0.0071 0.0065
Echinococcus multilocularis beta LACTamase domain containing family member 0.0099 0.0287 0.0281
Trichomonas vaginalis glucose transporter, putative 0.0743 0.2394 1
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0013 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0015
Echinococcus multilocularis Diacylglycerol kinase theta 0.0027 0.0051 0.0045
Brugia malayi Cytochrome P450 family protein 0.0026 0.0046 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0115 0.0337 0.0333
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Brugia malayi steroid hormone receptor 0.0018 0.0021 0.0018
Leishmania major hypothetical protein, conserved 0.0013 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0021 0.0015
Echinococcus granulosus defective proboscis extension response 0.0017 0.0017 0.0011
Entamoeba histolytica hypothetical protein 0.0027 0.0051 0.0352
Toxoplasma gondii LsmAD domain-containing protein 0.0021 0.003 0.0102
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Trichomonas vaginalis importin beta-1, putative 0.0065 0.0176 0.0712
Brugia malayi Cytochrome P450 family protein 0.0034 0.0075 0.0081
Echinococcus multilocularis solute carrier family 22 0.0743 0.2394 0.239
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0026 0.0046 0.0168
Schistosoma mansoni hypothetical protein 0.0026 0.0046 0.0041
Echinococcus multilocularis solute carrier family 22 0.0743 0.2394 0.239
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0061 0.0161 0.0155
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0021 0.0015
Trypanosoma cruzi sugar transporter, putative 0.0743 0.2394 1
Toxoplasma gondii HEAT repeat-containing protein 0.0081 0.0226 0.0921
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0047 0.0114 0.011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0115 0.0337 0.0333
Mycobacterium tuberculosis Conserved hypothetical protein 0.005 0.0125 0.0497
Brugia malayi protein kinase C II. 0.0475 0.1517 0.1765
Leishmania major pantothenate kinase subunit, putative 0.0013 0.0006 0.0006
Loa Loa (eye worm) AGC/PKN protein kinase 0.0448 0.1429 0.1424
Entamoeba histolytica protein kinase, putative 0.0452 0.1443 1
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0016 0.0014 0.0059
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0017 0.0017 0.0011
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0013 0.0006 0.0023
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0016 0.0014 0.0059
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0056 0.0146 0.014
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0026 0.0046 0.014
Leishmania major RNA-editing complex protein MP100, putative 0.0013 0.0006 0.0006
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0141 0.0423 0.1765
Schistosoma mansoni neutral sphingomyelinase 0.0013 0.0006 0.0001
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.005 0.0125 0.0119
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0016 0.0014 0.0059
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0066 0.0179 0.0724
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0083 0.0235 0.023
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0065 0.0176 0.0712
Echinococcus multilocularis serine:threonine protein kinase 38 0.0448 0.1429 0.1424
Onchocerca volvulus Huntingtin homolog 0.0113 0.0334 0.1372
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0017 0.0017 0.0011
Schistosoma mansoni hypothetical protein 0.0583 0.187 0.1867
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0061 0.0161 0.0155
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0743 0.2394 0.239
Plasmodium vivax sugar transporter, putative 0.0743 0.2394 1
Onchocerca volvulus 0.0099 0.0287 0.1177
Schistosoma mansoni inositol monophosphatase 0.0032 0.0065 0.006
Loa Loa (eye worm) hypothetical protein 0.025 0.078 0.0775
Echinococcus granulosus Rac GTPase activating protein 1 0.0027 0.0051 0.0045
Brugia malayi diacylglycerol kinase 0.0027 0.0051 0.0053
Brugia malayi hypothetical protein 0.0743 0.2394 0.2789
Trichomonas vaginalis conserved hypothetical protein 0.0743 0.2394 1
Trichomonas vaginalis AGC family protein kinase 0.0448 0.1429 0.5957
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.002 0.0082
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0147 0.0445 0.044
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0141 0.0423 0.1765
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0059 0.0156 0.0651
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0013 0.0006 0.0023
Plasmodium falciparum importin beta, putative 0.0081 0.0226 0.0921
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0027 0.0051 0.0045
Plasmodium vivax hexose transporter 0.0743 0.2394 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0013 0.0006 0.0023
Loa Loa (eye worm) kap beta 3 protein 0.0015 0.0012 0.0006
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.005 0.0125 0.0119
Schistosoma mansoni coup transcription factor 0.0018 0.0021 0.0016
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0015 0.001 0.0004
Echinococcus multilocularis inositol monophosphatase 1 0.0032 0.0065 0.0059
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0026 0.0046 0.0168
Loa Loa (eye worm) hypothetical protein 0.0032 0.0065 0.006
Leishmania major hypothetical protein, conserved 0.0013 0.0006 0.0006
Echinococcus granulosus protein kinase c eta type 0.0027 0.0051 0.0045
Mycobacterium ulcerans lipase LipD 0.0099 0.0287 0.1153
Schistosoma mansoni protein kinase 0.0018 0.002 0.0015
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.004 0.0092 0.2414
Entamoeba histolytica PH domain containing protein kinase, putative 0.0016 0.0014 0.01
Onchocerca volvulus 0.0743 0.2394 1
Onchocerca volvulus 0.0743 0.2394 1
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0074 0.0206 0.02
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0099 0.0287 0.0282
Trypanosoma brucei glucose transporter, putative 0.0743 0.2394 1
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Brugia malayi Immunoglobulin I-set domain containing protein 0.002 0.0028 0.0026
Echinococcus granulosus GTP binding nuclear protein Ran 0.0059 0.0156 0.015
Leishmania major GTP-binding protein, putative 0.0059 0.0156 0.0181
Onchocerca volvulus Tyrosine kinase homolog 0.0015 0.001 0.0017
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.0021 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0021 0.0015
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0026 0.0046 0.014
Trypanosoma brucei importin beta-1 subunit, putative 0.0081 0.0226 0.0941
Echinococcus multilocularis translational activator gcn1 0.0015 0.0012 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0026 0.0046 0.0168
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0011
Loa Loa (eye worm) hypothetical protein 0.0448 0.1429 0.1424
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0013 0.0006 0.004
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0634 0.2038 0.8509
Leishmania major importin beta-1 subunit, putative 0.0065 0.0176 0.0204
Trypanosoma brucei THT1 - hexose transporter, putative 0.0743 0.2394 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0013 0.0006 0.004
Schistosoma mansoni diacylglycerol kinase theta 0.0027 0.0051 0.0046
Echinococcus granulosus twitchin 0.0037 0.0083 0.0077
Schistosoma mansoni tyrosine kinase 0.0015 0.001 0.0005
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0112 0.0328 0.0382
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0054 0.0138 0.0552
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0039 0.0089 0.0083
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.0021 0.0015
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0178 0.0543 0.0538
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.0021 0.0015
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0023 0.0037 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.0021 0.0018
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0013 0.0006 0.0023
Schistosoma mansoni atypical protein kinase C 0.0475 0.1517 0.1513
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0032 0.0065 0.0271
Mycobacterium ulcerans glutaminase 0.0285 0.0894 0.37
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0032 0.0065 0.0249
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Echinococcus multilocularis titin 0.002 0.0028 0.0022
Brugia malayi polk-prov protein 0.0015 0.0012 0.0008
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0016 0.0014 0.0017
Trypanosoma cruzi mitochondrial protein 99, putative 0.0013 0.0006 0.0023
Leishmania major protein kinase, putative 0.0141 0.0423 0.0492
Echinococcus multilocularis geminin 0.0583 0.187 0.1866
Mycobacterium tuberculosis Probable esterase LipL 0.0099 0.0287 0.1177
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0011
Onchocerca volvulus Bile acid receptor homolog 0.0018 0.0021 0.0063
Brugia malayi Protein kinase c protein 2 0.0039 0.0089 0.0097
Schistosoma mansoni terminal deoxycytidyl transferase 0.005 0.0125 0.012
Trichomonas vaginalis AGC family protein kinase 0.0452 0.1443 0.6017
Echinococcus granulosus tyrosine protein kinase Lyn 0.0018 0.002 0.0014
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0075 0.0069
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0055 0.0143 0.0138
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Plasmodium vivax transportin, putative 0.0015 0.0012 0.0026
Echinococcus multilocularis protein kinase c epsilon type 0.0475 0.1517 0.1512
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0039 0.0089 0.0083
Loa Loa (eye worm) inositol-1 0.0032 0.0065 0.0059
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0026 0.0046 0.0168
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0056 0.0146 0.0164
Leishmania major endonuclease/exonuclease protein-like protein 0.0013 0.0006 0.0006
Loa Loa (eye worm) cytochrome P450 0.0026 0.0046 0.004
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0143 0.0576
Schistosoma mansoni hypothetical protein 0.0121 0.0359 0.0355
Echinococcus granulosus zinc finger protein 0.0021 0.0031 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0015
Loa Loa (eye worm) RasGEF domain-containing protein 0.0027 0.0051 0.0045
Echinococcus multilocularis protein kinase c iota type 0.0475 0.1517 0.1512
Trichomonas vaginalis conserved hypothetical protein 0.0743 0.2394 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.012 0.0355 0.035
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0162 0.0156
Trichomonas vaginalis glucose transporter, putative 0.0743 0.2394 1
Schistosoma mansoni DNA polymerase eta 0.005 0.0125 0.012
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Loa Loa (eye worm) latrophilin receptor protein 2 0.0056 0.0146 0.014
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.0125 0.0519
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0059 0.0156 0.0651
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.0021 0.0016
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0016 0.0014 0.0059
Brugia malayi major facilitator superfamily protein 0.0743 0.2394 0.2789
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0257 0.0804 0.0932
Trypanosoma cruzi mitochondrial protein 99, putative 0.0013 0.0006 0.0023
Loa Loa (eye worm) CAMK/PKD protein kinase 0.023 0.0715 0.071
Schistosoma mansoni cpg binding protein 0.0026 0.0046 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0074 0.0308
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Schistosoma mansoni protein kinase C 0.0027 0.0051 0.0046
Schistosoma mansoni glucose transport protein 0.0743 0.2394 0.2391
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0013 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0074 0.0308
Echinococcus granulosus activin receptor type 0.0018 0.002 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0012 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0026 0.0046 0.0168
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0027 0.0051 0.0045
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Loa Loa (eye worm) TAR-binding protein 0.0054 0.014 0.0134
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0066 0.0179 0.0202
Schistosoma mansoni diacylglycerol kinase theta 0.0027 0.0051 0.0046
Schistosoma mansoni rac gtpase activating protein 0.0027 0.0051 0.0046
Echinococcus granulosus methyl CpG binding domain protein 2 0.0015 0.001 0.0004
Trypanosoma brucei glucose transporter, putative 0.0743 0.2394 1
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0475 0.1517 0.1512
Schistosoma mansoni hypothetical protein 0.0583 0.187 0.1867
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.0021 0.0016
Echinococcus granulosus unc 13 munc13 0.0027 0.0051 0.0045
Trypanosoma cruzi DNA damage repair protein, putative 0.0015 0.0012 0.0051
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0027 0.0051 0.0046
Brugia malayi Cytochrome P450 family protein 0.0034 0.0075 0.0081
Entamoeba histolytica PH domain containing protein kinase, putative 0.0016 0.0014 0.01
Echinococcus granulosus sodium channel protein 0.0112 0.0328 0.0323
Toxoplasma gondii diacylglycerol kinase, putative 0.0027 0.0051 0.0188
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0074 0.0205 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0743 0.2394 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.005 0.0125 0.0497
Leishmania major cytochrome p450-like protein 0.0034 0.0075 0.0087
Loa Loa (eye worm) TK protein kinase 0.0156 0.0473 0.0467
Onchocerca volvulus 0.0743 0.2394 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0099 0.0287 0.0282
Toxoplasma gondii cytochrome p450 superfamily protein 0.0026 0.0046 0.0168
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0026 0.0046 0.014
Trypanosoma cruzi hexose transporter, putative 0.0743 0.2394 1
Echinococcus granulosus ceramide glucosyltransferase 0.0288 0.0905 0.09
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0012 0.0051
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0013 0.0006 0.0023
Trichomonas vaginalis ap endonuclease, putative 0.0066 0.0179 0.0724
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0045
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0026 0.0046 0.014
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0021 0.0031 0.1438
Echinococcus granulosus histone acetyltransferase KAT2B 0.0038 0.0088 0.0082
Schistosoma mansoni serine/threonine kinase 0.0448 0.1429 0.1425
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0021 0.0018
Entamoeba histolytica Ran family GTPase 0.0059 0.0156 0.1081
Loa Loa (eye worm) hypothetical protein 0.0121 0.0359 0.0354
Trichomonas vaginalis AGC family protein kinase 0.0452 0.1443 0.6017
Trichomonas vaginalis D-aminoacylase, putative 0.0099 0.0287 0.1177
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0743 0.2394 0.239
Entamoeba histolytica hypothetical protein 0.0061 0.0163 0.1131
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0026 0.0046 0.0168
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0037 0.0036
Entamoeba histolytica diacylglycerol kinase, putative 0.0027 0.0051 0.0352
Trypanosoma brucei DNA polymerase IV, putative 0.005 0.0125 0.0519
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0056 0.0146 0.0141
Brugia malayi RNA binding protein 0.0054 0.014 0.0157
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0178 0.0543 0.0628
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0075 0.0262
Loa Loa (eye worm) hypothetical protein 0.0178 0.0543 0.0538
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.0021 0.0015
Loa Loa (eye worm) hypothetical protein 0.0056 0.0146 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0074 0.0308
Giardia lamblia Histone acetyltransferase GCN5 0.0033 0.0071 0.0076
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0138 0.0525
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0013 0.0006 0.0023
Plasmodium falciparum protein serine/threonine kinase-1 0.0141 0.0423 0.1746
Schistosoma mansoni hypothetical protein 0.0056 0.0146 0.0141
Mycobacterium tuberculosis Conserved protein 0.0099 0.0287 0.1177
Loa Loa (eye worm) hypothetical protein 0.0099 0.0287 0.0281
Onchocerca volvulus Putative transporter 0.0743 0.2394 1
Leishmania major glucose transporter, lmgt3 0.0743 0.2394 0.2788
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0061 0.0161 0.065
Loa Loa (eye worm) hypothetical protein 0.0038 0.0086 0.008
Echinococcus multilocularis transportin 1 0.0015 0.0012 0.0006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0018 0.0021 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0026 0.0046 0.0168
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0021 0.0016
Brugia malayi Pre-SET motif family protein 0.0047 0.0114 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0423 0.0418
Leishmania major hypothetical protein, conserved 0.0013 0.0006 0.0006
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0059 0.0156 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0021 0.0016
Toxoplasma gondii AGC kinase 0.0448 0.1429 0.5957
Leishmania major DNA polymerase kappa, putative 0.0015 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0015
Schistosoma mansoni cpg binding protein 0.0029 0.0056 0.0051
Trichomonas vaginalis ap endonuclease, putative 0.0066 0.0179 0.0724
Schistosoma mansoni ap endonuclease 0.0066 0.0179 0.0174
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0038 0.0088 0.0343
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0026 0.0046 0.014
Brugia malayi latrophilin 2 splice variant baaae 0.0121 0.0359 0.0413
Trypanosoma brucei DNA polymerase IV, putative 0.005 0.0125 0.0519
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0061 0.0161 0.509
Schistosoma mansoni importin-beta 2 0.0015 0.0012 0.0007
Giardia lamblia DNA damage repair protein 0.0015 0.0012 0.0008
Entamoeba histolytica HEAT repeat domain containing protein 0.0015 0.0012 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0743 0.2394 1
Brugia malayi RNA recognition motif domain containing protein 0.0054 0.014 0.0157
Brugia malayi RhoGAP domain containing protein 0.0027 0.0051 0.0053
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0099 0.0287 0.0328
Brugia malayi TAR-binding protein 0.0054 0.014 0.0157
Echinococcus multilocularis solute carrier family 22 0.0743 0.2394 0.239
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0054 0.014 0.0134
Entamoeba histolytica hypothetical protein 0.0065 0.0176 0.1218
Trichomonas vaginalis penicillin-binding protein, putative 0.0099 0.0287 0.1177
Schistosoma mansoni ceramide glucosyltransferase 0.0288 0.0905 0.0901
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.0021 0.0015
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.2634 0.8586 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0061 0.0161 0.0624
Schistosoma mansoni tar DNA-binding protein 0.0054 0.014 0.0135
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0021 0.003 0.0024
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.0021 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0054 0.014 0.0135
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0027 0.0051 0.0045
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0026 0.0046 0.014
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.0021 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0026 0.0046 0.0168
Echinococcus multilocularis GPCR, family 2 0.0056 0.0146 0.014
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0046 0.019
Onchocerca volvulus 0.0743 0.2394 1
Plasmodium falciparum transportin 0.0015 0.0012 0.0026
Trypanosoma cruzi DNA damage repair protein, putative 0.0015 0.0012 0.0051
Echinococcus granulosus NDR protein kinase 0.0448 0.1429 0.1424
Trypanosoma brucei DNA polymerase IV, putative 0.005 0.0125 0.0519
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0016 0.0014 0.01
Entamoeba histolytica acetyltransferase, GNAT family 0.0033 0.0071 0.0493
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0423 0.1746
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Entamoeba histolytica diacylglycerol kinase, putative 0.0027 0.0051 0.0352
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0026 0.0046 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0012 0.0051
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0743 0.2394 0.239
Onchocerca volvulus 0.0743 0.2394 1
Echinococcus granulosus translational activator gcn1 0.0015 0.0012 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0743 0.2394 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0075 0.0069
Brugia malayi glutaminase DH11.1 0.0285 0.0894 0.1037
Brugia malayi hypothetical protein 0.0113 0.0334 0.0383
Schistosoma mansoni protein kinase C mu 0.0257 0.0804 0.0799
Echinococcus granulosus solute carrier family 22 0.0743 0.2394 0.239
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0026 0.0046 0.014
Echinococcus multilocularis sodium channel protein 0.0112 0.0328 0.0323
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0021 0.0015
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0743 0.2394 0.239
Leishmania major glucose transporter/membrane transporter D2, putative 0.0743 0.2394 0.2788
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.002 0.0082
Brugia malayi PHD-finger family protein 0.0026 0.0046 0.0047
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0013 0.0006 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.1517 0.1513
Brugia malayi beta-lactamase family protein 0.0099 0.0287 0.0328
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0141 0.0423 0.1765
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0018 0.0021 0.0063
Onchocerca volvulus 0.0365 0.1158 0.4824
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0066 0.0179 0.0173
Schistosoma mansoni unc-13 (munc13) 0.0027 0.0051 0.0046
Schistosoma mansoni hypothetical protein 0.0013 0.0006 0.0001
Schistosoma mansoni hypothetical protein 0.086 0.2777 0.2773
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0015 0.001 0.0004
Schistosoma mansoni hypothetical protein 0.0018 0.002 0.0015
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0013 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0162 0.0157
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0021 0.0016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0047 0.0114 0.0455
Schistosoma mansoni tyrosine kinase 0.0147 0.0445 0.044
Schistosoma mansoni vesicular amine transporter 0.0024 0.004 0.0036
Leishmania major hypothetical protein, conserved 0.0013 0.0006 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0448 0.1429 0.5957
Brugia malayi Cytochrome P450 family protein 0.0144 0.0434 0.05
Echinococcus granulosus N chimaerin 0.0027 0.0051 0.0045
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.005 0.0125 0.0497
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0287 0.0281
Trichomonas vaginalis glucose transporter, putative 0.0743 0.2394 1
Brugia malayi major facilitator superfamily protein 0.0743 0.2394 0.2789
Entamoeba histolytica hypothetical protein 0.0061 0.0163 0.1131
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0743 0.2394 0.239
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0054 0.0138 0.0132
Onchocerca volvulus 0.0743 0.2394 1
Plasmodium vivax ataxin-2 like protein, putative 0.0021 0.003 0.0102
Echinococcus granulosus Diacylglycerol kinase theta 0.0027 0.0051 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Plasmodium vivax serine/threonine kinase-1, putative 0.0141 0.0423 0.1746
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Trichomonas vaginalis AGC family protein kinase 0.0452 0.1443 0.6017
Onchocerca volvulus 0.002 0.0028 0.0093
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.0021 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0011
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0016 0.0014 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0026 0.0046 0.0168
Echinococcus granulosus transportin 1 0.0015 0.0012 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0026 0.0046 0.0168
Brugia malayi Protein kinase domain containing protein 0.0448 0.1429 0.1661
Echinococcus granulosus fetal alzheimer antigen falz 0.0021 0.003 0.0024
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0015 0.0012 0.0048
Echinococcus granulosus Solute carrier family 22 5 0.2145 0.6986 0.6985
Giardia lamblia Ceramide glucosyltransferase 0.0131 0.039 0.0448
Schistosoma mansoni vav2 0.0032 0.0065 0.006
Onchocerca volvulus 0.0743 0.2394 1
Echinococcus granulosus synaptic vesicle 2 protein 0.0743 0.2394 0.239
Echinococcus granulosus dna polymerase eta 0.005 0.0125 0.0119
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.0125 0.0519
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0021 0.0018
Toxoplasma gondii facilitative glucose transporter GT1 0.0743 0.2394 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.0021 0.0015
Leishmania major glucose transporter, lmgt2 0.0743 0.2394 0.2788
Loa Loa (eye worm) hypothetical protein 0.0218 0.0677 0.0672
Brugia malayi hypothetical protein 0.0021 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0015
Entamoeba histolytica protein kinase, putative 0.0016 0.0014 0.01
Trichomonas vaginalis set domain proteins, putative 0.0365 0.1158 0.4824
Trypanosoma brucei PAB1-binding protein , putative 0.0021 0.003 0.0125
Trichomonas vaginalis D-aminoacylase, putative 0.0099 0.0287 0.1177
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0026 0.0046 0.0053
Loa Loa (eye worm) beta-lactamase 0.0099 0.0287 0.0281
Loa Loa (eye worm) major facilitator superfamily transporter 0.0743 0.2394 0.239
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Echinococcus granulosus roundabout 2 0.0025 0.0045 0.0039
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trichomonas vaginalis hypothetical protein 0.0015 0.0012 0.0026
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0059 0.0156 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0452 0.1443 0.6017
Trichomonas vaginalis ran, putative 0.0059 0.0156 0.0629
Loa Loa (eye worm) acetyltransferase 0.0126 0.0373 0.0368
Brugia malayi Major Facilitator Superfamily protein 0.0743 0.2394 0.2789
Trypanosoma cruzi hexose transporter, putative 0.0743 0.2394 1
Schistosoma mansoni serine/threonine-protein kinase 0.0016 0.0014 0.001
Loa Loa (eye worm) hypothetical protein 0.0099 0.0287 0.0281
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0045
Echinococcus granulosus beta LACTamase domain containing family member 0.0099 0.0287 0.0281
Schistosoma mansoni tar DNA-binding protein 0.0054 0.014 0.0135
Onchocerca volvulus 0.0018 0.0021 0.0063
Echinococcus multilocularis zinc finger protein 0.0021 0.0031 0.0026
Trypanosoma cruzi PAB1-binding protein , putative 0.0021 0.003 0.0125
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0138 0.0133
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.0021 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.0125 0.0519
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0027 0.005 0.0207
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0475 0.1517 0.1512
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0114 0.011
Leishmania major protein kinase, putative 0.0016 0.0014 0.0017
Echinococcus granulosus titin 0.002 0.0028 0.0022
Brugia malayi p70 ribosomal S6 kinase beta 0.0448 0.1429 0.1661
Trichomonas vaginalis esterase, putative 0.0099 0.0287 0.1177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0021 0.0015
Trypanosoma cruzi ISWI complex protein 0.0013 0.0005 0.0019
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.002 0.0028 0.0022
Echinococcus multilocularis dna polymerase eta 0.005 0.0125 0.0119
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0021 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0115 0.0337 0.0332
Mycobacterium tuberculosis Conserved protein 0.0099 0.0287 0.1177
Onchocerca volvulus 0.0027 0.0051 0.0188
Onchocerca volvulus 0.0218 0.0677 0.281
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0743 0.2394 1
Schistosoma mansoni glutaminase 0.0285 0.0894 0.0889
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0026 0.0046 0.0168
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0743 0.2394 1
Brugia malayi Major Facilitator Superfamily protein 0.0743 0.2394 0.2789
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0013 0.0006 0.004
Brugia malayi ImpB/MucB/SamB family protein 0.005 0.0125 0.0139
Schistosoma mansoni carbon catabolite repressor protein 0.0013 0.0006 0.0001
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0147 0.0445 0.044
Mycobacterium leprae conserved hypothetical protein 0.0099 0.0287 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0115 0.0337 0.0332
Onchocerca volvulus 0.0245 0.0766 0.3182
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0066 0.0179 0.0745
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0743 0.2394 0.239
Mycobacterium leprae Probable lipase LipE 0.0099 0.0287 1
Toxoplasma gondii sugar transporter ST2 0.0743 0.2394 1
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0028 0.0023
Schistosoma mansoni cpg binding protein 0.0029 0.0056 0.0051
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0028 0.0054 0.0927
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0141 0.0423 0.1765
Schistosoma mansoni unc-13 (munc13) 0.0027 0.0051 0.0046
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0066 0.0179 0.0745
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0099 0.0287 0.1177
Brugia malayi Hr1 repeat family protein 0.0448 0.1429 0.1661
Onchocerca volvulus 0.0743 0.2394 1
Schistosoma mansoni sugar transporter 0.0743 0.2394 0.2391
Echinococcus granulosus neuroglian 0.0025 0.0045 0.0039
Loa Loa (eye worm) glutaminase 0.0285 0.0894 0.0889
Echinococcus multilocularis tar DNA binding protein 0.0054 0.014 0.0134
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0017 0.0017 0.0012
Loa Loa (eye worm) sugar transporter 0.0743 0.2394 0.239
Echinococcus multilocularis dual specificity protein kinase clk2 0.0141 0.0423 0.0417
Onchocerca volvulus 0.0099 0.0287 0.1177
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0016 0.0014 0.0059
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0031 0.0062 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0162 0.0157
Entamoeba histolytica protein kinase, putative 0.0016 0.0014 0.01
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.0021 0.0015
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0032 0.0065 0.0271
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.0021 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0099 0.0287 0.1197
Trypanosoma brucei glucose transporter, putative 0.0743 0.2394 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0065 0.0176 0.0712
Echinococcus multilocularis calcium activated potassium channel 0.0019 0.0024 0.0018
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Schistosoma mansoni DNA polymerase IV / kappa 0.0015 0.0012 0.0008
Leishmania major folate/biopterin transporter, putative 0.0016 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0045
Mycobacterium ulcerans integral membrane transport protein 0.0743 0.2394 1
Schistosoma mansoni hypothetical protein 0.0056 0.0146 0.0141
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0026 0.0046 0.014
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0436 0.1391 0.5798
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0026 0.0046 0.014
Leishmania major glucose transporter, lmgt1 0.0743 0.2394 0.2788
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0448 0.1429 0.1424
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0021 0.0018
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0027 0.0051 0.0045
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0013 0.0006 0.004
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0061 0.0161 0.0412
Trichomonas vaginalis DNA polymerase eta, putative 0.005 0.0125 0.0497
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Trypanosoma brucei RNA editing exonuclease 2 0.0013 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0015
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0061 0.0161 0.065
Trypanosoma brucei glucose transporter, putative 0.0743 0.2394 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0016 0.0014 0.01
Brugia malayi RhoGAP domain containing protein 0.0027 0.0051 0.0053
Brugia malayi nuclear receptor NHR-88 0.0018 0.0021 0.0018
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0061 0.0161 0.8987
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0138 0.0133
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.005 0.0125 0.0119
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0099 0.0287 0.0281
Schistosoma mansoni inositol monophosphatase 0.0032 0.0065 0.006
Mycobacterium leprae Conserved hypothetical protein 0.0026 0.0046 0.0593
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Onchocerca volvulus 0.0743 0.2394 1
Onchocerca volvulus Huntingtin homolog 0.0113 0.0334 0.1372
Echinococcus granulosus snurportin 1 0.086 0.2777 0.2772
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0039 0.0089 0.0083
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0112 0.0328 0.0323
Loa Loa (eye worm) CAMK protein kinase 0.002 0.0028 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.0021 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0448 0.1429 0.1425
Mycobacterium tuberculosis Probable lipase LipE 0.0099 0.0287 0.1177
Trichomonas vaginalis penicillin-binding protein, putative 0.0099 0.0287 0.1177
Leishmania major serine/threonine-protein kinase a, putative 0.0016 0.0014 0.0017
Echinococcus multilocularis dna polymerase kappa 0.005 0.0125 0.0119
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0016 0.0014 0.0059
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0016 0.0014 0.0059
Echinococcus granulosus dna polymerase kappa 0.005 0.0125 0.0119
Brugia malayi Pleckstrin Homology Domain 0.0032 0.0065 0.0069
Loa Loa (eye worm) sugar transporter 0.0743 0.2394 0.239
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0013 0.0006 0.0023
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0051 0.0053
Brugia malayi Inositol-1 0.0032 0.0065 0.0069
Leishmania major cytochrome p450-like protein 0.0026 0.0046 0.0053
Loa Loa (eye worm) hypothetical protein 0.0129 0.0385 0.0379
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0013 0.0006 0.004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0039
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.002 0.0028 0.0022
Trypanosoma cruzi ISWI complex protein 0.0013 0.0005 0.0019
Brugia malayi exodeoxyribonuclease III family protein 0.0066 0.0179 0.0202
Echinococcus granulosus raf serine:threonine protein kinase 0.0033 0.0071 0.0065
Echinococcus granulosus FTZ F1 alpha 0.0018 0.0021 0.0015
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0066 0.0179 0.0724
Brugia malayi protein unc-22 0.002 0.0028 0.0026
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0027 0.0051 0.0045
Echinococcus granulosus cpg binding protein 0.0029 0.0056 0.005
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Brugia malayi Protein kinase domain containing protein 0.0074 0.0205 0.0232
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.1517 0.1513
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trypanosoma cruzi hexose transporter, putative 0.0743 0.2394 1
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0028 0.0023
Trypanosoma cruzi DNA polymerase eta, putative 0.005 0.0125 0.0519
Echinococcus granulosus fibroblast growth factor receptor 4 0.0147 0.0445 0.044
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0743 0.2394 0.239
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.004 0.0092 0.0363
Plasmodium falciparum DNA repair protein REV1, putative 0.0015 0.0012 0.0028
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0027 0.0051 0.0045
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0066 0.0179 0.0487
Trichomonas vaginalis glutaminase, putative 0.0285 0.0894 0.3718
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0115 0.0337 0.0332
Onchocerca volvulus 0.0743 0.2394 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.005 0.0125 0.0863
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0012 0.0051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0066 0.0179 0.0745
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0126 0.0373 0.0368
Schistosoma mansoni synaptojanin 0.0013 0.0006 0.0001
Echinococcus granulosus myotubularin protein 13 0.0032 0.0065 0.006
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0141 0.0423 0.1746
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0047 0.0114 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.0021 0.0018
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.002 0.0082
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0027 0.0051 0.0046
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0016 0.0014 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0021 0.0018
Toxoplasma gondii ABC1 family protein 0.0099 0.0287 0.1177
Echinococcus multilocularis Immunoglobulin 0.0017 0.0017 0.0011
Echinococcus multilocularis Immunoglobulin 0.0017 0.0017 0.0011
Echinococcus multilocularis ceramide glucosyltransferase 0.0288 0.0905 0.09
Loa Loa (eye worm) hypothetical protein 0.006 0.016 0.0154
Echinococcus multilocularis peptidase Clp (S14 family) 0.004 0.0092 0.0087
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0066 0.0179 0.0173
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0126 0.0373 0.0369
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0448 0.1429 0.1424
Echinococcus granulosus Protein kinase C brain isozyme 0.0475 0.1517 0.1512
Treponema pallidum exodeoxyribonuclease (exoA) 0.0066 0.0179 1
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0026 0.0046 0.014
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0743 0.2394 1
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0013 0.0006 0.004
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0026 0.0046 0.014
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0016 0.0014 0.0037
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0059 0.0156 0.0629
Echinococcus granulosus solute carrier family 22 0.0743 0.2394 0.239
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0743 0.2394 1
Schistosoma mansoni serine/threonine protein kinase 0.0448 0.1429 0.1425
Mycobacterium ulcerans DNA polymerase IV 0.005 0.0125 0.047
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0021 0.003 0.0102
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0013 0.0006 0.004
Loa Loa (eye worm) cytochrome P450 family protein 0.0144 0.0434 0.0429
Giardia lamblia Sugar-proton symporter 0.0743 0.2394 0.2789
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0016 0.0014 0.0037
Mycobacterium ulcerans beta-lactamase 0.0099 0.0287 0.1153
Entamoeba histolytica hypothetical protein 0.0061 0.0163 0.1131
Loa Loa (eye worm) hypothetical protein 0.0127 0.0379 0.0374
Echinococcus multilocularis serine threonine protein kinase 0.0448 0.1429 0.1424
Echinococcus multilocularis roundabout 2 0.0025 0.0045 0.0039
Trypanosoma brucei DNA polymerase eta, putative 0.005 0.0125 0.0519
Echinococcus granulosus protein kinase c iota type 0.0475 0.1517 0.1512
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0061 0.0161 0.065
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0056 0.0146 0.014
Onchocerca volvulus 0.0743 0.2394 1
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Echinococcus granulosus importin 5 0.0015 0.0012 0.0006
Mycobacterium tuberculosis Probable hydrolase 0.0099 0.0287 0.1177
Toxoplasma gondii protein kinase domain-containing protein 0.0016 0.0014 0.0037
Brugia malayi acetyltransferase, GNAT family protein 0.0126 0.0373 0.0429
Brugia malayi RhoGEF domain containing protein 0.0027 0.0051 0.0053
Schistosoma mansoni serine/threonine-protein kinase 0.0016 0.0014 0.001
Trichomonas vaginalis D-aminoacylase, putative 0.0099 0.0287 0.1177
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0056 0.0146 0.014
Trypanosoma brucei protein kinase, putative 0.0018 0.002 0.0082
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0061 0.0163 0.0158
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.002 0.0138
Onchocerca volvulus 0.0743 0.2394 1
Schistosoma mansoni tar DNA-binding protein 0.0054 0.014 0.0135
Entamoeba histolytica protein kinase, putative 0.0448 0.1429 0.99
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0013 0.0006 0.004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0015
Loa Loa (eye worm) hypothetical protein 0.0061 0.0162 0.0156
Loa Loa (eye worm) CXXC zinc finger family protein 0.0026 0.0046 0.004
Brugia malayi protein kinase C3,putative 0.0039 0.0089 0.0097
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0013 0.0006 0.0023
Trypanosoma brucei glucose transporter, putative 0.0743 0.2394 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0061 0.0161 0.0624
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Toxoplasma gondii HEAT repeat-containing protein 0.0015 0.0012 0.0026
Onchocerca volvulus 0.0743 0.2394 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0061 0.0163 0.0158
Brugia malayi beta-lactamase family protein 0.0099 0.0287 0.0328
Echinococcus multilocularis twitchin 0.002 0.0028 0.0022
Plasmodium vivax DNA repair protein REV1, putative 0.0015 0.0012 0.0028
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Mycobacterium leprae putative cytochrome p450 0.0026 0.0046 0.0593
Trichomonas vaginalis AGC family protein kinase 0.0448 0.1429 0.5957
Trichomonas vaginalis AGC family protein kinase 0.0452 0.1443 0.6017
Echinococcus multilocularis serine:threonine protein kinase N2 0.0448 0.1429 0.1424
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0115 0.0337 0.0333
Schistosoma mansoni ran 0.0059 0.0156 0.0151
Loa Loa (eye worm) TK/ROR protein kinase 0.0015 0.001 0.0004
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0032 0.0065 0.0271
Echinococcus multilocularis 0.0129 0.0385 0.0379
Brugia malayi diacylglycerol kinase 0.0027 0.0051 0.0053
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0013 0.0006 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.0021 0.0018
Brugia malayi hypothetical protein 0.0061 0.0163 0.0184
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0115 0.0337 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0743 0.2394 1
Brugia malayi Sugar transporter family protein 0.0743 0.2394 0.2789
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0026 0.0046 0.0168
Echinococcus granulosus GPCR family 2 0.0056 0.0146 0.014
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0018 0.002 0.0014
Trypanosoma brucei sugar transporter, putative 0.0743 0.2394 1
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0016 0.0014 0.0037
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0021 0.0015
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Mycobacterium ulcerans sugar transporter 0.0743 0.2394 1
Loa Loa (eye worm) AGC/AKT protein kinase 0.0452 0.1443 0.1438
Echinococcus granulosus peptidase Clp S14 family 0.004 0.0092 0.0087
Toxoplasma gondii sugar transporter ST3 0.0743 0.2394 1
Brugia malayi Importin beta-1 subunit 0.0081 0.0226 0.0257
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0026 0.0046 0.019
Loa Loa (eye worm) ceramide glucosyltransferase 0.0288 0.0905 0.09
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0026 0.0046 0.014
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0059 0.0156 0.015
Loa Loa (eye worm) major facilitator superfamily transporter 0.0743 0.2394 0.239
Brugia malayi Pre-SET motif family protein 0.0321 0.1013 0.1176
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0448 0.1429 0.1424
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0026 0.0046 0.019
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0038 0.0088 0.0343
Trypanosoma brucei glucose transporter 1E 0.0743 0.2394 1
Toxoplasma gondii exonuclease III APE 0.0066 0.0179 0.0724
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.086 0.2777 0.2772
Loa Loa (eye worm) hypothetical protein 0.0099 0.0287 0.0281
Loa Loa (eye worm) hypothetical protein 0.0061 0.0161 0.0155
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0013 0.0006 0.0023
Leishmania major DNA polymerase eta, putative 0.0015 0.0012 0.0014
Entamoeba histolytica hypothetical protein 0.0061 0.0163 0.1131
Echinococcus granulosus importin subunit beta 1 0.0081 0.0226 0.022
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0061 0.0161 0.5
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0039
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0013 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0016 0.0014 0.0059
Schistosoma mansoni ap endonuclease 0.0066 0.0179 0.0174
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0061 0.0161 0.5
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0026 0.0046 0.0168
Brugia malayi Muscleblind-like protein 0.0127 0.0379 0.0436
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0099 0.0287 0.1177
Brugia malayi Protein kinase domain containing protein 0.0448 0.1429 0.1661
Schistosoma mansoni importin beta-1 0.0081 0.0226 0.0221
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0038 0.0088 0.0343
Toxoplasma gondii transporter, major facilitator family protein 0.0743 0.2394 1
Loa Loa (eye worm) hypothetical protein 0.0218 0.0677 0.0672
Brugia malayi Protein kinase domain containing protein 0.0141 0.0423 0.0487
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0015 0.0012 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0448 0.1429 0.1425
Trypanosoma cruzi hexose transporter 0.0743 0.2394 1
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.3066 1 1
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0458 0.1462 0.1458
Brugia malayi ecdysteroid receptor 0.0018 0.0021 0.0018
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Schistosoma mansoni glucose transporter 0.0743 0.2394 0.2391
Echinococcus multilocularis thyroid hormone receptor alpha 0.0018 0.0021 0.0015
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0075 0.0311
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0045
Echinococcus granulosus geminin 0.0583 0.187 0.1866
Schistosoma mansoni glucose transport protein 0.0743 0.2394 0.2391
Plasmodium vivax hypothetical protein, conserved 0.0099 0.0287 0.1177
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0013 0.0006 0.0023
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0026 0.0046 0.014
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0059 0.0156 0.015
Plasmodium falciparum ataxin-2 like protein, putative 0.0021 0.003 0.0102
Echinococcus granulosus dual specificity protein kinase clk2 0.0141 0.0423 0.0417
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0013 0.0006 0.0023
Leishmania major protein kinase, putative 0.0018 0.002 0.0023
Schistosoma mansoni hypothetical protein 0.0743 0.2394 0.2391
Echinococcus multilocularis synaptic vesicle 2 protein 0.0743 0.2394 0.239
Loa Loa (eye worm) raf kinase 0.0027 0.0051 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Schistosoma mansoni bromodomain containing protein 0.0058 0.0153 0.0149
Mycobacterium ulcerans DNA polymerase IV 0.005 0.0125 0.047
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0147 0.0445 0.044
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0056 0.0146 0.014
Echinococcus granulosus titin 0.002 0.0028 0.0022
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0013 0.0006 0.004
Entamoeba histolytica hypothetical protein 0.0016 0.0014 0.01
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0016 0.0014 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Echinococcus multilocularis muscleblind protein 1 0.0127 0.0379 0.0374
Giardia lamblia Kinase, AGC AKT 0.2629 0.8571 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0016 0.0014 0.01
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0026 0.0046 0.014
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.0021 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Leishmania major DNA polymerase eta, putative 0.005 0.0125 0.0145
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0448 0.1429 0.1424
Leishmania major hypothetical protein, conserved 0.0015 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0045
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0075 0.0311
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0026 0.0046 0.014
Toxoplasma gondii sugar transporter ST1 0.0743 0.2394 1
Plasmodium falciparum calcium-dependent protein kinase 7 0.0016 0.0014 0.0037
Loa Loa (eye worm) hypothetical protein 0.005 0.0125 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0162 0.0156
Loa Loa (eye worm) hypothetical protein 0.0033 0.0069 0.0063
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Echinococcus multilocularis N chimaerin 0.0027 0.0051 0.0045
Echinococcus granulosus protein kinase c epsilon type 0.0475 0.1517 0.1512
Echinococcus granulosus serine/threonine protein kinase 0.0016 0.0014 0.0009
Brugia malayi kap beta 3 protein 0.0015 0.0012 0.0007
Schistosoma mansoni nocturnin 0.0013 0.0006 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Brugia malayi Bromodomain containing protein 0.0068 0.0186 0.0211
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0031 0.0062 0.0057
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0743 0.2394 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0021 0.0015
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0026 0.0046 0.014
Entamoeba histolytica protein kinase, putative 0.0452 0.1443 1
Leishmania major hypothetical protein, conserved 0.0743 0.2394 0.2788
Trypanosoma brucei glucose transporter, putative 0.0743 0.2394 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.0021 0.0018
Echinococcus multilocularis Rac GTPase activating protein 1 0.0027 0.0051 0.0045
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0021 0.0018
Trypanosoma brucei importin beta-1 subunit, putative 0.0081 0.0226 0.0941
Schistosoma mansoni protein kinase 0.0018 0.002 0.0015
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0743 0.2394 0.2391
Schistosoma mansoni hypothetical protein 0.0027 0.0051 0.0046
Plasmodium vivax SET domain protein, putative 0.0047 0.0114 0.0455
Leishmania major myo-inositol/proton symporter (MIT) 0.0743 0.2394 0.2788
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0016 0.0014 0.0059
Brugia malayi Calcitonin receptor-like protein seb-1 0.0178 0.0543 0.0628
Trypanosoma brucei glucose transporter, putative 0.0743 0.2394 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.0334 0.0328
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0099 0.0287 0.1177
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0011
Echinococcus granulosus tar DNA binding protein 0.0054 0.014 0.0134
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0066 0.0179 0.0173
Echinococcus multilocularis protein kinase c eta type 0.0027 0.0051 0.0045
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2694 0.8784 0.8783
Brugia malayi Probable ClpP-like protease 0.0061 0.0161 0.0181
Trypanosoma brucei unspecified product 0.005 0.0125 0.0519
Brugia malayi ribosomal protein S6 kinase alpha 3 0.2629 0.8571 1
Plasmodium falciparum protein kinase, putative 0.0018 0.002 0.0059
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0007
Brugia malayi Ras association domain family 1 isoform A 0.0027 0.0051 0.0053
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0066 0.0179 0.0724
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.0021 0.0018
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0026 0.0046 0.0168
Schistosoma mansoni hypothetical protein 0.0056 0.0146 0.0141
Trypanosoma cruzi glucose transporter, putative 0.0743 0.2394 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0033 0.0071 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0743 0.2394 1
Leishmania major hypothetical protein, conserved 0.0099 0.0287 0.0334
Schistosoma mansoni glucose transport protein 0.0743 0.2394 0.2391
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0021 0.0016
Loa Loa (eye worm) importin-beta domain-containing protein 0.0015 0.0012 0.0006
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0743 0.2394 0.239
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0054 0.0138 0.0132
Schistosoma mansoni sugar transporter 0.0743 0.2394 0.2391
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Schistosoma mansoni sugar transporter 0.0743 0.2394 0.2391
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0013 0.0006 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.0021 0.0018
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.0021 0.0018
Echinococcus granulosus hypothetical protein 0.0129 0.0385 0.0379
Loa Loa (eye worm) hypothetical protein 0.0081 0.0226 0.022
Echinococcus granulosus calcium activated potassium channel 0.0019 0.0024 0.0018
Loa Loa (eye worm) hypothetical protein 0.0099 0.0287 0.0281
Schistosoma mansoni cell adhesion molecule 0.0017 0.0017 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0021 0.0018
Echinococcus multilocularis myotubularin protein 13 0.0032 0.0065 0.006
Brugia malayi cytochrome P450 0.0026 0.0046 0.0047
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0448 0.1429 0.1424
Onchocerca volvulus 0.0099 0.0287 0.1177
Loa Loa (eye worm) hypothetical protein 0.0041 0.0096 0.009
Echinococcus granulosus solute carrier family 22 0.0743 0.2394 0.239
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0066 0.0179 0.0698
Entamoeba histolytica hypothetical protein 0.0016 0.0014 0.01
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0027 0.0051 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Trypanosoma brucei DNA damage repair protein, putative 0.0015 0.0012 0.0051
Schistosoma mansoni zinc finger protein 0.0021 0.0031 0.0027
Plasmodium falciparum hexose transporter 0.0743 0.2394 1
Schistosoma mansoni cript-related 0.0013 0.0006 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0021 0.0015
Trichomonas vaginalis inositol monophosphatase, putative 0.0032 0.0065 0.0249
Trypanosoma brucei chrX additional, unordered contigs 0.0015 0.0012 0.0051
Leishmania major protein kinase, putative 0.0141 0.0423 0.0492
Onchocerca volvulus 0.0743 0.2394 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.0125 0.0519
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0743 0.2394 1
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0017 0.0017 0.0012
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0011
Entamoeba histolytica protein kinase, putative 0.0448 0.1429 0.99
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0013 0.0006 0.0023
Echinococcus granulosus inositol monophosphatase 1 0.0032 0.0065 0.0059
Leishmania major hypothetical protein, conserved 0.0021 0.003 0.0035
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0026 0.0046 0.014
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0045
Echinococcus granulosus muscleblind protein 0.0127 0.0379 0.0374
Trichomonas vaginalis myo-inositol transporter, putative 0.0743 0.2394 1
Schistosoma mansoni cytochrome P450 0.0026 0.0046 0.0041
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0044 0.0107 0.0101
Echinococcus multilocularis snurportin 1 0.086 0.2777 0.2772
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.0021 0.0018
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0141 0.0423 0.1765
Echinococcus granulosus solute carrier family 22 0.0743 0.2394 0.239
Brugia malayi CXXC zinc finger family protein 0.0026 0.0046 0.0047
Schistosoma mansoni synaptojanin 0.0013 0.0006 0.0001
Giardia lamblia Hexose transporter 0.0743 0.2394 0.2789
Brugia malayi hypothetical protein 0.0743 0.2394 0.2789
Loa Loa (eye worm) hypothetical protein 0.0127 0.0379 0.0374
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0026 0.0046 0.0168
Onchocerca volvulus 0.0743 0.2394 1
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Loa Loa (eye worm) hypothetical protein 0.0743 0.2394 0.239
Trypanosoma brucei THT1 - hexose transporter, putative 0.0743 0.2394 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0032 0.0065 0.0249
Entamoeba histolytica PH domain containing protein kinase, putative 0.0016 0.0014 0.01
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0018 0.002 0.0014
Echinococcus multilocularis solute carrier family 22 0.0743 0.2394 0.239
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0743 0.2394 0.239
Schistosoma mansoni hypothetical protein 0.0056 0.0146 0.0141
Onchocerca volvulus 0.0743 0.2394 1
Trichomonas vaginalis AGC family protein kinase 0.0452 0.1443 0.6017
Brugia malayi hypothetical protein 0.0743 0.2394 0.2789
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0012 0.0051
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0115 0.0337 0.0387
Echinococcus multilocularis rac serine:threonine kinase 0.0016 0.0014 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0099 0.0287 0.1197
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.0021 0.0016
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0448 0.1429 0.1424
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0017 0.0013
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trypanosoma brucei glucose transporter 2A 0.0743 0.2394 1
Brugia malayi Major Facilitator Superfamily protein 0.0743 0.2394 0.2789
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0448 0.1429 0.1424
Schistosoma mansoni nephrin 0.0025 0.0045 0.004
Trichomonas vaginalis AGC family protein kinase 0.0452 0.1443 0.6017
Schistosoma mansoni sugar transporter 0.0743 0.2394 0.2391
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0026 0.0046 0.0168
Giardia lamblia DINP protein human, muc B family 0.005 0.0125 0.0139
Schistosoma mansoni protein kinase C mu 0.0027 0.0051 0.0046
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Schistosoma mansoni hypothetical protein 0.0061 0.0163 0.0159
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0012 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.1517 0.1513
Brugia malayi Latrophilin receptor protein 2 0.0056 0.0146 0.0164
Loa Loa (eye worm) AGC/NDR protein kinase 0.0448 0.1429 0.1424
Onchocerca volvulus 0.025 0.078 0.3242
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0125 0.0519
Loa Loa (eye worm) glutaminase 2 0.0285 0.0894 0.0889
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Echinococcus multilocularis 0.0026 0.0046 0.004
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0055 0.0143 0.0138
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0013 0.0006 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0021 0.003 0.0125
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0032 0.0065 0.0076
Trypanosoma cruzi hexose transporter, putative 0.0743 0.2394 1
Echinococcus multilocularis importin subunit beta 1 0.0081 0.0226 0.022
Echinococcus multilocularis cpg binding protein 0.0029 0.0056 0.005
Onchocerca volvulus 0.0026 0.0046 0.0169
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0059 0.0156 0.0651
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.001 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.3066 1 1
Echinococcus granulosus cytochrome P450 2K1 0.0026 0.0046 0.004
Mycobacterium tuberculosis Conserved protein 0.0099 0.0287 0.1177
Trypanosoma brucei unspecified product 0.0034 0.0074 0.0308
Brugia malayi beta-lactamase 0.0099 0.0287 0.0328
Schistosoma mansoni ran 0.0059 0.0156 0.0151
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.001 0.0005
Onchocerca volvulus 0.0047 0.0114 0.0455
Trichomonas vaginalis conserved hypothetical protein 0.0743 0.2394 1
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0141 0.0423 0.0417
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0015 0.001 0.0004
Echinococcus granulosus protein kinase C gamma type 0.0448 0.1429 0.1424
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Trichomonas vaginalis sugar transporter, putative 0.0743 0.2394 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0021 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0075 0.0069
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.0021 0.0015
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.005 0.0125 0.012
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0066 0.0179 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0071 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0021 0.0015
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0013 0.0006 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0089 0.0084
Brugia malayi Fibronectin type III domain containing protein 0.0017 0.0017 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0089 0.0084
Mycobacterium tuberculosis Probable lipase LipD 0.0099 0.0287 0.1177
Trypanosoma brucei THT1 - hexose transporter, putative 0.0743 0.2394 1
Brugia malayi ImpB/MucB/SamB family protein 0.005 0.0125 0.0139
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0015 0.0012 0.0028
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0026 0.0046 0.019
Leishmania major cytochrome p450-like protein 0.0026 0.0046 0.0053
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.005 0.0125 0.0145
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0138 0.0525
Brugia malayi hypothetical protein 0.0017 0.0017 0.0013
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.0021 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0014 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0473 0.0545
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.0021 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0054 0.014 0.0135
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0138 0.0525
Mycobacterium ulcerans esterase/lipase LipP 0.0099 0.0287 0.1153
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0026 0.0046 0.014
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0028 0.0054 0.0204
Loa Loa (eye worm) hypothetical protein 0.0099 0.0287 0.0281
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0013 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0245 0.0766 0.076
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0011
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0021 0.0031 0.0104
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0059 0.0156 0.0629
Schistosoma mansoni peptidase Clp (S14 family) 0.0061 0.0161 0.0156
Toxoplasma gondii aldehyde dehydrogenase 0.0054 0.0138 0.0552
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0026 0.0046 0.014
Brugia malayi Ceramide glucosyltransferase 0.0288 0.0905 0.105
Trichomonas vaginalis sugar transport protein, putative 0.0743 0.2394 1
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0016 0.0014 0.0037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0015
Entamoeba histolytica p21-activated kinase 0.0016 0.0014 0.01
Brugia malayi nuclear hormone receptor 0.0018 0.0021 0.0018
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0016 0.0014 0.0059
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0013 0.0006 0.0023
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0026 0.0046 0.0168
Echinococcus multilocularis muscleblind protein 0.0127 0.0379 0.0374
Brugia malayi Bromodomain containing protein 0.0036 0.0079 0.0085
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0321 0.1013 0.1008
Echinococcus multilocularis activin receptor type 0.0018 0.002 0.0014
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0013 0.0006 0.004
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0059 0.0156 0.0629
Trypanosoma brucei unspecified product 0.0034 0.0074 0.0308
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.3066 1 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0032 0.0065 0.0452
Trypanosoma brucei DNA damage repair protein, putative 0.0015 0.0012 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0026 0.0046 0.0168
Echinococcus multilocularis importin 5 0.0015 0.0012 0.0006
Entamoeba histolytica protein kinase, putative 0.0016 0.0014 0.01
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0074 0.0205 0.0199
Entamoeba histolytica protein kinase, putative 0.0016 0.0014 0.01
Loa Loa (eye worm) RNA binding protein 0.0054 0.014 0.0134
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0743 0.2394 1
Echinococcus granulosus serine:threonine protein kinase N2 0.0448 0.1429 0.1424

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 10 uM Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence scanner ChEMBL. 24900342
IC50 (binding) = 25 uM Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysis ChEMBL. 24900342
Inhibition (binding) Inhibition of glucosylceramide synthase in mouse RAW cells up to 20 uM preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence scanner ChEMBL. 24900342

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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