Detailed information for compound 1742080

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1559.26 | Formula: C75H108ClN23O12
  • H donors: 18 H acceptors: 17 LogP: 5.07 Rotable bonds: 58
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCNC(=O)CNC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@H](Cc1ccc(cc1)Cl)NC(=O)[C@@H](Cc1ccc2c(c1)cccc2)NC(=O)C)CO)CCCCNc1n[nH]c(n1)N)CCCCNc1n[nH]c(n1)N)CC(C)C)CCCCNC(C)C
  • InChi: 1S/C75H108ClN23O12/c1-7-80-62(102)42-84-70(110)61-24-17-35-99(61)71(111)55(23-12-13-32-81-45(4)5)88-65(105)56(36-44(2)3)89-64(104)54(22-11-15-34-83-75-94-73(78)96-98-75)86-63(103)53(21-10-14-33-82-74-93-72(77)95-97-74)87-69(109)60(43-100)92-68(108)59(40-49-18-16-31-79-41-49)91-67(107)58(38-47-26-29-52(76)30-27-47)90-66(106)57(85-46(6)101)39-48-25-28-50-19-8-9-20-51(50)37-48/h8-9,16,18-20,25-31,37,41,44-45,53-61,81,100H,7,10-15,17,21-24,32-36,38-40,42-43H2,1-6H3,(H,80,102)(H,84,110)(H,85,101)(H,86,103)(H,87,109)(H,88,105)(H,89,104)(H,90,106)(H,91,107)(H,92,108)(H4,77,82,93,95,97)(H4,78,83,94,96,98)/t53-,54-,55-,56-,57+,58-,59+,60-,61+/m0/s1
  • InChiKey: UAIAWSKPOHEZLS-LNELXCANSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens gonadotropin-releasing hormone receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi GnHR receptor homolog Get druggable targets OG5_131719 All targets in OG5_131719
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0092 0.0379 0.452
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0075 0.0305 0.4205
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0128
Echinococcus multilocularis wingless type MMTV integration site family 0.0016 0.0045 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0071
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0092 0.0225
Mycobacterium tuberculosis Probable reductase 0.0075 0.0305 0.4205
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.002 0.006 0.042
Loa Loa (eye worm) hypothetical protein 0.0017 0.0049 0.0121
Onchocerca volvulus 0.012 0.0507 0.1225
Brugia malayi DOMON domain containing protein 0.0075 0.0306 0.0748
Echinococcus multilocularis lysosomal alpha glucosidase 0.0091 0.0376 0.0367
Loa Loa (eye worm) norepinephrine transporter 0.0929 0.4091 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.001 0.0017 0.0132
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.001 0.0017 0.0132
Brugia malayi Pre-SET motif family protein 0.0258 0.1118 0.2733
Loa Loa (eye worm) hypothetical protein 0.0006 0.0001 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.0175 0.205
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.003 0.0104 0.0095
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0086 0.0665
Onchocerca volvulus 0.0294 0.1276 0.3108
Trichomonas vaginalis sucrase-isomaltase, putative 0.002 0.0063 0.0483
Echinococcus multilocularis G protein coupled receptor 139 0.2263 1 1
Schistosoma mansoni myosin xvIII 0.012 0.0507 0.0504
Echinococcus multilocularis dnaJ subfamily B 0.0523 0.2288 0.2281
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.002 0.006 0.042
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0014 0.0035 0.0353
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.012 0.0507 0.0504
Echinococcus granulosus G protein coupled receptor 139 0.012 0.0507 0.0497
Schistosoma mansoni hypothetical protein 0.0331 0.144 0.1438
Onchocerca volvulus 0.0008 0.001 0.0008
Brugia malayi hypothetical protein 0.0046 0.0175 0.0428
Mycobacterium ulcerans hypothetical protein 0.0102 0.0424 0.4559
Echinococcus multilocularis mitogen activated protein kinase 0.0029 0.0102 0.0092
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.0507 0.0504
Echinococcus multilocularis neuropeptides capa receptor 0.012 0.0507 0.0497
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0024 0.0207
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Brugia malayi DOMON domain containing protein 0.0075 0.0306 0.0748
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0008 0.001 0.0039
Leishmania major hypothetical protein, conserved 0.0025 0.0086 0.0962
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0198 0.0484
Brugia malayi Latrophilin receptor protein 2 0.0086 0.0356 0.0871
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0071 0.0551
Echinococcus granulosus cytochrome P450 2K1 0.002 0.006 0.0051
Entamoeba histolytica hypothetical protein 0.0067 0.0272 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0198 0.0485
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0273 0.1184 0.2895
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0086 0.0665
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Echinococcus multilocularis thioredoxin glutathione reductase 0.0033 0.0119 0.0109
Brugia malayi putative neuropeptide receptor 0.012 0.0507 0.1238
Brugia malayi wnt family protein 0.0016 0.0045 0.011
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0158 0.0672 0.1643
Loa Loa (eye worm) G-protein coupled receptor 0.012 0.0507 0.1238
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0086 0.0962
Entamoeba histolytica hypothetical protein 0.0067 0.0272 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0325 0.1414 0.1405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.0507 0.0504
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.012 0.0507 0.0497
Echinococcus granulosus mitogen activated protein kinase 0.0029 0.0102 0.0092
Schistosoma mansoni wnt related 0.0016 0.0045 0.0043
Echinococcus granulosus thioredoxin glutathione reductase 0.0033 0.0119 0.0109
Schistosoma mansoni inositol monophosphatase 0.0046 0.0178 0.0176
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Echinococcus granulosus inositol monophosphatase 1 0.0046 0.0178 0.0169
Schistosoma mansoni lipoxygenase 0.0033 0.0117 0.0115
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.002 0.0063 0.0153
Giardia lamblia Histone acetyltransferase GCN5 0.0029 0.0101 0.955
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0198 0.0196
Schistosoma mansoni biogenic amine (dopamine) receptor 0.012 0.0507 0.0504
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0198 0.0484
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0024 0.0078 0.087
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0198 0.0196
Loa Loa (eye worm) TYRA-2 protein 0.012 0.0507 0.1238
Leishmania major phosphatidylinositol 3-kinase, putative 0.001 0.0017 0.0132
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0929 0.4091 0.4089
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.006 0.0656
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.006 0.0553
Leishmania major cytochrome p450-like protein 0.002 0.006 0.0656
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.0061 0.0244 0.0597
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0044 0.0339
Brugia malayi Cytochrome P450 family protein 0.0025 0.0082 0.0199
Schistosoma mansoni smad 0.0011 0.0022 0.002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.012 0.0507 0.0497
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0078 0.032 0.0311
Trichomonas vaginalis penicillin-binding protein, putative 0.0025 0.0086 0.0665
Brugia malayi Cell death protein 3 precursor 0.0055 0.0218 0.0533
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Brugia malayi CXXC zinc finger family protein 0.0037 0.0136 0.0331
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.006 0.0553
Trichomonas vaginalis glutathione reductase, putative 0.0011 0.0024 0.0177
Loa Loa (eye worm) hypothetical protein 0.0008 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.006 0.0553
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.006 0.0553
Onchocerca volvulus 0.012 0.0507 0.1225
Echinococcus multilocularis WNT 0.0016 0.0045 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0198 0.0484
Loa Loa (eye worm) transcription factor SMAD2 0.0162 0.0691 0.1689
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni eyes absent homolog 0.0061 0.0244 0.0242
Trypanosoma brucei RNA helicase, putative 0.0085 0.0348 0.4148
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.012 0.0507 0.0504
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0092 0.0225
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0105 0.0816
Echinococcus granulosus microsomal glutathione S transferase 3 0.0184 0.0787 0.0778
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.012 0.0507 0.0504
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni hypothetical protein 0.012 0.0507 0.0504
Echinococcus granulosus 7TM GPCR rhodopsin 0.012 0.0507 0.0497
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.002 0.006 0.042
Brugia malayi hypothetical protein 0.0008 0.001 0.0023
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.012 0.0507 0.0497
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.002 0.006 0.042
Onchocerca volvulus 0.0075 0.0306 0.0734
Toxoplasma gondii ABC1 family protein 0.0025 0.0086 0.1078
Brugia malayi hypothetical protein 0.0237 0.1022 0.2497
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0158 0.0672 0.0663
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0075 0.0305 0.7744
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0055 0.0422
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0079 0.007
Loa Loa (eye worm) wnt-4 protein 0.0016 0.0045 0.011
Brugia malayi DOMON domain containing protein 0.0075 0.0306 0.0748
Schistosoma mansoni opsin-like receptor 0.012 0.0507 0.0504
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0198 0.047
Echinococcus multilocularis isocitrate dehydrogenase 0.003 0.0104 0.0095
Echinococcus granulosus single minded 2 0.0052 0.0206 0.0196
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.001 0.0071
Brugia malayi Dopamine receptor protein 2 0.012 0.0507 0.1238
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0079 0.0077
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0079 0.0194
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0017 0.0129
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.006 0.0757
Loa Loa (eye worm) hypothetical protein 0.0158 0.0672 0.1643
Loa Loa (eye worm) hypothetical protein 0.0061 0.0244 0.0597
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0193 0.083 0.2028
Echinococcus multilocularis fmrfamide receptor 0.012 0.0507 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0071
Brugia malayi Isocitrate dehydrogenase 0.003 0.0104 0.0255
Loa Loa (eye worm) hypothetical protein 0.0392 0.1712 0.4185
Loa Loa (eye worm) CWN-2 protein 0.0016 0.0045 0.011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0086 0.0209
Brugia malayi intermediate filament protein 0.0037 0.0137 0.0335
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0083 0.0342 0.889
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0041 0.0157 0.3154
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0011 0.0024 0.0057
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0158 0.0672 0.1643
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0018 0.0055 0.0587
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Schistosoma mansoni hypothetical protein 0.007 0.0282 0.0279
Echinococcus granulosus tm gpcr rhodopsin 0.012 0.0507 0.0497
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0067 0.0272 0.0263
Loa Loa (eye worm) hypothetical protein 0.0158 0.0672 0.1643
Schistosoma mansoni biogenic amine (dopamine) receptor 0.012 0.0507 0.0504
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0029 0.0102 0.1158
Echinococcus granulosus orexin receptor type 2 0.012 0.0507 0.0497
Loa Loa (eye worm) hypothetical protein 0.0158 0.0672 0.1643
Echinococcus multilocularis WNT 0.0016 0.0045 0.0035
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0107 0.0446 0.0437
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.003 0.0105 0.0095
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0011 0.0024 0.0014
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.0198 0.0189
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni biogenic amine (5HT) receptor 0.012 0.0507 0.0504
Schistosoma mansoni hypothetical protein 0.0331 0.144 0.1438
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0008 0.001 0.0024
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0079 0.0077
Schistosoma mansoni sodium/chloride dependent transporter 0.0158 0.0673 0.0671
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0022 0.0054
Schistosoma mansoni protein tyrosine phosphatase 0.0008 0.001 0.0007
Brugia malayi G protein-coupled receptor F59B2.13 0.012 0.0507 0.1238
Onchocerca volvulus 0.0051 0.0198 0.047
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0198 0.0196
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.001 0.0019 0.0009
Trichomonas vaginalis maltase-glucoamylase, putative 0.002 0.0063 0.0483
Loa Loa (eye worm) zinc finger protein 0.0584 0.2561 0.6261
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0011 0.0024 0.0207
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0082 0.0914
Echinococcus granulosus lipoxygenase domain containing protein 0.0012 0.0025 0.0015
Onchocerca volvulus 0.0008 0.001 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.0507 0.0504
Loa Loa (eye worm) MH2 domain-containing protein 0.0162 0.0691 0.1689
Echinococcus multilocularis lysosomal alpha glucosidase 0.0091 0.0376 0.0367
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.002 0.0063 0.0784
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.001 0.0071
Mycobacterium tuberculosis Possible two component transcriptional regulatory protein (probably LuxR-family) 0.0091 0.0378 0.5294
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0086 0.0962
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0033 0.0119 0.142
Mycobacterium ulcerans aldehyde dehydrogenase 0.0038 0.0143 0.1359
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0045 0.0171 0.0418
Mycobacterium ulcerans nitrate/nitrite response regulator protein NarL 0.0091 0.0378 0.4026
Brugia malayi MH2 domain containing protein 0.0011 0.0022 0.0053
Brugia malayi tailless protein 0.0024 0.0079 0.0194
Brugia malayi Wnt-2 protein precursor 0.0016 0.0045 0.011
Loa Loa (eye worm) hypothetical protein 0.0016 0.0045 0.011
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0025 0.0086 0.0209
Brugia malayi hypothetical protein 0.0027 0.0092 0.0225
Schistosoma mansoni cpg binding protein 0.0039 0.0145 0.0143
Schistosoma mansoni cpg binding protein 0.0037 0.0136 0.0133
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.003 0.0105 0.0102
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0198 0.0189
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0008 0.001 0.0007
Echinococcus granulosus Protein Wnt-04 0.0016 0.0045 0.0035
Toxoplasma gondii aldehyde dehydrogenase 0.0038 0.0143 0.1807
Mycobacterium ulcerans two component transcriptional regulatory protein DevR 0.0091 0.0378 0.4026
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Trichomonas vaginalis alpha-glucosidase, putative 0.0008 0.0006 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.0507 0.0497
Brugia malayi Tachykinin-like peptides receptor 99D 0.012 0.0507 0.1238
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0198 0.0189
Echinococcus granulosus allatostatin A receptor 0.012 0.0507 0.0497
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.002 0.006 0.042
Mycobacterium ulcerans hypothetical protein 0.0091 0.0378 0.4026
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0033 0.0117 0.0108
Echinococcus granulosus sex peptide receptor 0.012 0.0507 0.0497
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.012 0.0507 0.0504
Brugia malayi Tyrosine-protein kinase abl-1 0.0086 0.0355 0.0868
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0029 0.0102 0.1158
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.001 0.0071
Mycobacterium tuberculosis Probable dehydrogenase 0.0075 0.0305 0.4205
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.0198 0.0189
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0086 0.0356 0.0871
Schistosoma mansoni polycystin 1-related 0.0012 0.0025 0.0022
Echinococcus granulosus biogenic amine 5HT receptor 0.012 0.0507 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0017 0.0129
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.002 0.0017
Onchocerca volvulus 0.0037 0.0137 0.032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0071 0.0551
Loa Loa (eye worm) hypothetical protein 0.0025 0.0086 0.0209
Brugia malayi RNase H family protein 0.0023 0.0073 0.0178
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0023 0.0073 0.321
Echinococcus multilocularis neuropeptides capa receptor 0.012 0.0507 0.0497
Brugia malayi Protein-tyrosine phosphatase 0.0008 0.001 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.0008 0.0006 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0086 0.0665
Mycobacterium ulcerans hypothetical protein 0.0025 0.0086 0.0707
Giardia lamblia NADH oxidase lateral transfer candidate 0.0011 0.0024 0.1454
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.0507 0.0497
Onchocerca volvulus 0.0008 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0075 0.0305 0.4205
Onchocerca volvulus 0.012 0.0507 0.1225
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.006 0.0553
Leishmania major mitochondrial DNA polymerase beta 0.0193 0.083 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0092 0.0225
Loa Loa (eye worm) hypothetical protein 0.0016 0.0045 0.011
Schistosoma mansoni sodium/chloride dependent transporter 0.0158 0.0672 0.067
Mycobacterium leprae Conserved hypothetical protein 0.002 0.006 0.0177
Schistosoma mansoni opsin-like receptor 0.012 0.0507 0.0504
Plasmodium falciparum transporter, putative 0.0158 0.0672 1
Onchocerca volvulus 0.0008 0.001 0.0008
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0198 0.0485
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0011 0.0022 0.0012
Schistosoma mansoni glutaminase 0.021 0.0903 0.0901
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0158 0.0672 0.067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0044 0.034
Echinococcus multilocularis tumor protein p63 0.0423 0.1846 0.1838
Brugia malayi cytoplasmic intermediate filament protein 0.002 0.0061 0.0149
Onchocerca volvulus 0.0075 0.0306 0.0734
Brugia malayi hypothetical protein 0.0029 0.0104 0.0253
Trichomonas vaginalis mercuric reductase, putative 0.0011 0.0024 0.0177
Onchocerca volvulus 0.0158 0.0672 0.163
Echinococcus multilocularis GPCR, family 2 0.0086 0.0356 0.0347
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0025 0.0086 0.0083
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0008 0.0006 0.0043
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0045 0.0171 0.0162
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0008 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0238 0.1027 0.251
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.012 0.0507 0.0497
Onchocerca volvulus 0.0008 0.001 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.006 0.0553
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.006 0.0553
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Onchocerca volvulus 0.012 0.0507 0.1225
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0078 0.032 0.0311
Loa Loa (eye worm) hypothetical protein 0.0038 0.014 0.0343
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0008 0.001 0.0024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0079 0.007
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0198 0.0484
Echinococcus multilocularis sodium and chloride dependent glycine 0.0158 0.0672 0.0663
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0325 0.1414 0.3456
Brugia malayi hypothetical protein 0.0027 0.0092 0.0225
Echinococcus granulosus somatostatin receptor 0.012 0.0507 0.0497
Trypanosoma brucei unspecified product 0.0024 0.0082 0.0913
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0258 0.1118 0.2734
Onchocerca volvulus 0.0008 0.001 0.0008
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0078 0.032 0.0782
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0198 0.0485
Mycobacterium tuberculosis Probable oxidoreductase 0.0083 0.0342 0.4759
Loa Loa (eye worm) hypothetical protein 0.0158 0.0672 0.1643
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0018 0.0055 0.0422
Loa Loa (eye worm) hypothetical protein 0.0025 0.0086 0.0209
Echinococcus granulosus g protein coupled receptor 0.012 0.0507 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0044 0.034
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.002 0.001
Toxoplasma gondii hypothetical protein 0.0031 0.0111 0.1404
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0029 0.0102 0.1282
Brugia malayi GnHR receptor homolog 0.0676 0.2968 0.7256
Echinococcus granulosus fmrfamide receptor 0.012 0.0507 0.0497
Giardia lamblia Kinase, CMGC MAPK 0.0029 0.0102 0.9665
Brugia malayi ORL1-like opioid receptor 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.0062 0.0247 0.0605
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0033 0.0117 0.0108
Trichomonas vaginalis ribonuclease H1, putative 0.0023 0.0073 0.0566
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.002 0.006 0.042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.001 0.0071
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0011 0.0024 0.0014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.012 0.0507 0.0497
Brugia malayi G protein-coupled receptor 0.012 0.0507 0.1238
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.012 0.0507 0.1238
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0105 0.0816
Onchocerca volvulus 0.012 0.0507 0.1225
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.001 0.0017 0.0015
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0038 0.0143 0.1787
Loa Loa (eye worm) hypothetical protein 0.0051 0.0198 0.0485
Brugia malayi bHLH-PAS transcription factor 0.0052 0.0206 0.0502
Loa Loa (eye worm) hypothetical protein 0.0025 0.0086 0.0209
Loa Loa (eye worm) hypothetical protein 0.0158 0.0672 0.1643
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0078 0.032 0.0311
Brugia malayi MH1 domain containing protein 0.0011 0.0022 0.0053
Schistosoma mansoni intermediate filament proteins 0.0037 0.0137 0.0135
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.001 0.0071
Leishmania major alpha glucosidase II subunit, putative 0.002 0.0063 0.0681
Echinococcus multilocularis Smad4 0.0011 0.0022 0.0012
Brugia malayi wnt family protein 0.0016 0.0045 0.011
Onchocerca volvulus 0.0008 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.006
Schistosoma mansoni cpg binding protein 0.0039 0.0145 0.0143
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0071 0.0551
Plasmodium vivax multidomain scavenger receptor, putative 0.0012 0.0025 0.0017
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0198 0.0189
Schistosoma mansoni phosphoglucomutase 0.0023 0.0073 0.0071
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0008 0.001 0.0039
Giardia lamblia Ribonuclease H 0.0023 0.0073 0.666
Schistosoma mansoni hypothetical protein 0.012 0.0507 0.0504
Echinococcus multilocularis orexin receptor type 2 0.012 0.0507 0.0497
Echinococcus multilocularis dro:myosuppressin receptor 0.012 0.0507 0.0497
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0198 0.0485
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Onchocerca volvulus 0.0008 0.001 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.001 0.0071
Brugia malayi Protein-tyrosine phosphatase 0.0008 0.001 0.0023
Brugia malayi nuclear receptor NHR-88 0.0024 0.0079 0.0194
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0198 0.0484
Echinococcus multilocularis somatostatin receptor 0.012 0.0507 0.0497
Loa Loa (eye worm) hypothetical protein 0.0929 0.4091 1
Trypanosoma brucei PAB1-binding protein , putative 0.0046 0.0175 0.205
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0086 0.0958
Schistosoma mansoni hypothetical protein 0.0012 0.0025 0.0022
Onchocerca volvulus 0.012 0.0507 0.1225
Loa Loa (eye worm) hypothetical protein 0.0273 0.1184 0.2895
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0079 0.007
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0046 0.0178 0.2084
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.0175 0.234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0044 0.0339
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0045 0.0171 0.1999
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0079 0.007
Schistosoma mansoni smad1 5 8 and 0.0011 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0198 0.0189
Mycobacterium ulcerans two component transcriptional regulator 0.0091 0.0378 0.4026
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0046 0.0178 0.1757
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0079 0.007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Onchocerca volvulus 0.0012 0.0025 0.0045
Toxoplasma gondii MAPEG family protein 0.0184 0.0787 1
Schistosoma mansoni hypothetical protein 0.0187 0.0801 0.0799
Onchocerca volvulus 0.012 0.0507 0.1225
Echinococcus multilocularis aryl hydrocarbon receptor 0.0018 0.0055 0.0045
Echinococcus granulosus hypothetical protein 0.012 0.0507 0.0497
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0038 0.014 0.0131
Brugia malayi MAP kinase sur-1 0.0029 0.0102 0.0248
Onchocerca volvulus 0.012 0.0507 0.1225
Mycobacterium tuberculosis Conserved protein 0.0025 0.0086 0.093
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Schistosoma mansoni alpha glucosidase 0.002 0.0063 0.006
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Brugia malayi nuclear receptor NHR-88 0.0051 0.0198 0.0484
Echinococcus multilocularis transfer RNA-Lys 0.0052 0.0206 0.0196
Echinococcus granulosus smad 0.0011 0.0022 0.0012
Trypanosoma cruzi target of rapamycin kinase 3 0.0024 0.0078 0.087
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0198 0.0196
Loa Loa (eye worm) DR-78 0.0024 0.0079 0.0194
Brugia malayi hypothetical protein 0.0008 0.001 0.0023
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Brugia malayi nuclear hormone receptor 0.0051 0.0198 0.0484
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.002 0.006 0.042
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0198 0.0196
Toxoplasma gondii isocitrate dehydrogenase 0.003 0.0104 0.1316
Toxoplasma gondii isocitrate dehydrogenase 0.003 0.0104 0.1316
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.003 0.0105 0.1196
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0046 0.0178 0.2252
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.006 0.0553
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0008 0.001 0.0007
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0082 0.02
Schistosoma mansoni lipoxygenase 0.0012 0.0025 0.0022
Schistosoma mansoni wnt related 0.0016 0.0045 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0078 0.0604
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.006 0.0553
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0158 0.0672 0.067
Leishmania major cytochrome p450-like protein 0.002 0.006 0.0656
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.0507 0.0497
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.003 0.0104 0.0095
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0078 0.032 0.0318
Onchocerca volvulus 0.0055 0.0218 0.0519
Schistosoma mansoni aryl hydrocarbon receptor 0.0071 0.0287 0.0285
Trypanosoma brucei ribonuclease H1 0.0023 0.0073 0.081
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0082 0.0914
Schistosoma mansoni biogenic amine (5HT) receptor 0.012 0.0507 0.0504
Loa Loa (eye worm) serotonin transporter b 0.0929 0.4091 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0198 0.0484
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0063 0.0681
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0008 0.001 0.0007
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.006 0.0656
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0008 0.001 0.0024
Mycobacterium tuberculosis Probable transcriptional regulatory protein (LuxR-family) 0.0091 0.0378 0.5294
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0029 0.0102 0.0249
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.002 0.0061 0.0149
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0018 0.0055 0.0587
Echinococcus multilocularis neuropeptide receptor 0.2263 1 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.002 0.001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0038 0.014 0.1774
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.007 0.0282 0.0689
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0071
Loa Loa (eye worm) inositol-1 0.0046 0.0178 0.0435
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Loa Loa (eye worm) hypothetical protein 0.0016 0.0045 0.011
Echinococcus granulosus serotonin receptor 0.012 0.0507 0.0497
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0158 0.0672 0.1643
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0063 0.0483
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.002 0.0063 0.0483
Trypanosoma brucei protein tyrosine phosphatase 1 0.0008 0.001 0.0039
Brugia malayi Melatonin receptor type 1A 0.012 0.0507 0.1238
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0067 0.0272 0.0263
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0392 0.1712 0.1704
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.012 0.0507 0.0504
Trichomonas vaginalis glutaminase, putative 0.021 0.0903 0.7075
Trichomonas vaginalis maltase-glucoamylase, putative 0.0008 0.0006 0.0043
Brugia malayi sulfakinin receptor protein 0.012 0.0507 0.1238
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0079 0.0194
Onchocerca volvulus 0.0929 0.4091 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.006 0.0553
Schistosoma mansoni aldehyde dehydrogenase 0.0038 0.0143 0.0141
Schistosoma mansoni hypothetical protein 0.012 0.0507 0.0504
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.0507 0.0497
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0027 0.0094 0.1059
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0102 0.0791
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0273 0.1184 0.2895
Loa Loa (eye worm) hypothetical protein 0.0392 0.1712 0.4185
Onchocerca volvulus 0.0008 0.001 0.0008
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0029 0.007
Onchocerca volvulus Huntingtin homolog 0.0237 0.1022 0.2486
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Plasmodium vivax amine transporter, putative 0.0158 0.0672 1
Trichomonas vaginalis helicase, putative 0.0008 0.001 0.0071
Echinococcus granulosus g-protein coupled receptor 0.012 0.0507 0.0497
Brugia malayi ecdysone receptor 0.0024 0.0079 0.0194
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.0507 0.0497
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0024 0.0082 0.0913
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.002 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0092 0.0225
Schistosoma mansoni hypothetical protein 0.0044 0.0167 0.0165
Echinococcus granulosus zinc finger transcription factor gli2 0.0584 0.2561 0.2554
Echinococcus granulosus apoptotic protease activating factor 1 0.0055 0.0218 0.0209
Schistosoma mansoni loxhd1 0.0012 0.0025 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0052 0.04
Brugia malayi Cytochrome P450 family protein 0.002 0.006 0.0147
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0102 0.0791
Echinococcus multilocularis smad 0.0011 0.0022 0.0012
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0198 0.0196
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.0507 0.0497
Echinococcus granulosus neuropeptides capa receptor 0.012 0.0507 0.0497
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.0507 0.0497
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0029 0.0072
Schistosoma mansoni growth hormone secretagogue receptor 0.012 0.0507 0.0504
Entamoeba histolytica hypothetical protein 0.0067 0.0272 1
Loa Loa (eye worm) doublecortin family protein 0.0012 0.0025 0.006
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0158 0.0672 0.0663
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0336
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0063 0.0483
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0078 0.032 0.0318
Echinococcus multilocularis wnt family member wnt11 2 0.0016 0.0045 0.0035
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0198 0.0189
Schistosoma mansoni amine GPCR 0.012 0.0507 0.0504
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0011 0.0024 0.0207
Schistosoma mansoni hypothetical protein 0.002 0.0064 0.0061
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.006 0.0553
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Leishmania major ribonuclease H1, putative 0.0023 0.0073 0.081
Plasmodium vivax hypothetical protein, conserved 0.0158 0.0672 1
Schistosoma mansoni survival motor neuron protein 0.007 0.0282 0.0279
Echinococcus multilocularis 0.002 0.006 0.0051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0198 0.0189
Echinococcus multilocularis G-protein coupled receptor, putative 0.012 0.0507 0.0497
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0046 0.0178 0.1389
Schistosoma mansoni neuropeptide receptor 0.2263 1 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.002 0.006 0.042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.001 0.0071
Onchocerca volvulus 0.012 0.0507 0.1225
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0008 0.001 0.0023
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.003 0.0105 0.0095
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0038 0.014 0.0131
Mycobacterium tuberculosis Possible nitrate/nitrite response transcriptional regulatory protein NarL 0.0091 0.0378 0.5294
Brugia malayi PAS domain containing protein 0.0071 0.0287 0.0702
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0012 0.0028 0.026
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0094 0.1059
Onchocerca volvulus 0.012 0.0507 0.1225
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0079 0.007
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0092 0.0379 0.452
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0025 0.0086 0.0083
Trichomonas vaginalis pten, drome, putative 0.0008 0.001 0.0069
Loa Loa (eye worm) neuropeptide F receptor 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.0025 0.0086 0.0209
Brugia malayi wnt family protein 0.0016 0.0045 0.011
Echinococcus multilocularis sodium and chloride dependent glycine 0.0158 0.0672 0.0663
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0325 0.1414 0.1405
Mycobacterium ulcerans esterase/lipase LipP 0.0025 0.0086 0.0707
Brugia malayi Calcitonin receptor-like protein seb-1 0.0273 0.1184 0.2895
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0198 0.0484
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0078 0.0604
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0019 0.0056 0.0601
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0017 0.0129
Loa Loa (eye worm) hypothetical protein 0.0929 0.4091 1
Plasmodium vivax SET domain protein, putative 0.0038 0.014 0.1802
Schistosoma mansoni wnt related 0.0016 0.0045 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0078 0.0604
Brugia malayi hypothetical protein 0.0008 0.001 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0063 0.0483
Mycobacterium tuberculosis Probable lipase LipE 0.0025 0.0086 0.093
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0008 0.001 0.0007
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0198 0.0196
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.002 0.0063 0.2112
Echinococcus multilocularis lipoxygenase domain containing protein 0.0012 0.0025 0.0015
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.001 0.0019 0.0009
Brugia malayi glutathione reductase 0.0033 0.0119 0.0289
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.006 0.0656
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0086 0.0356 0.0347
Loa Loa (eye worm) glutaminase 0.021 0.0903 0.2207
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0198 0.0189
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0024 0.0207
Loa Loa (eye worm) hypothetical protein 0.0025 0.0086 0.0209
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0008 0.001 0.0121
Onchocerca volvulus Neuropeptide F receptor homolog 0.012 0.0507 0.1225
Giardia lamblia GTOR 0.003 0.0105 1
Schistosoma mansoni adenoreceptor 0.012 0.0507 0.0504
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.014 0.0138
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0198 0.0189
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.003 0.0104 0.0095
Loa Loa (eye worm) thioredoxin reductase 0.0033 0.0119 0.029
Trypanosoma brucei protein kinase, putative 0.0029 0.0102 0.1158
Loa Loa (eye worm) hypothetical protein 0.0027 0.0092 0.0225
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0158 0.0672 0.067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0009 0.006
Schistosoma mansoni protein tyrosine phosphatase 0.0008 0.001 0.0007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Echinococcus multilocularis lipoxygenase domain containing protein 0.0012 0.0025 0.0015
Onchocerca volvulus 0.0024 0.0079 0.0179
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.001 0.0017 0.0132
Brugia malayi Pre-SET motif family protein 0.0038 0.014 0.0343
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.0507 0.0504
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0055 0.0422
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.002 0.0064 0.0054
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0079 0.007
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0008 0.001 0.0024
Brugia malayi AKH receptor 0.012 0.0507 0.1238
Echinococcus multilocularis neutral alpha glucosidase AB 0.002 0.0063 0.0053
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.012 0.0507 0.1238
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0198 0.0196
Brugia malayi neuropeptide F receptor 0.012 0.0507 0.1238
Schistosoma mansoni smad1 5 8 and 0.0011 0.0022 0.002
Onchocerca volvulus 0.0158 0.0672 0.163
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0193 0.083 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Echinococcus multilocularis mitogen activated protein kinase 3 0.0029 0.0102 0.0092
Brugia malayi MH1 domain containing protein 0.0011 0.0022 0.0053
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0158 0.0672 0.067
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0193 0.083 1
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0392 0.1712 0.1704
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.003 0.0105 0.3708
Echinococcus granulosus Protein Wnt-5 0.0016 0.0045 0.0035
Echinococcus multilocularis RUN 0.0012 0.0025 0.0015
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0199 0.0856 0.2091
Echinococcus granulosus mothers against decapentaplegic 5 0.0011 0.0022 0.0012
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0082 0.02
Loa Loa (eye worm) hypothetical protein 0.0929 0.4091 1
Brugia malayi latrophilin 2 splice variant baaae 0.0187 0.0801 0.1958
Echinococcus granulosus protein Wnt 1 0.0016 0.0045 0.0035
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.001 0.0071
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0008 0.001 0.0121
Brugia malayi Glycosyl hydrolases family 31 protein 0.0091 0.0376 0.0919
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.006 0.0553
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.002 0.006 0.042
Brugia malayi hypothetical protein 0.0012 0.0025 0.006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.012 0.0507 0.0504
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0008 0.001 0.0007
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.001 0.0019 0.0016
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.003 0.0104 0.1248
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0158 0.0672 0.0663
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0045 0.0171 0.6197
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0051 0.0198 0.0485
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0024 0.0207
Loa Loa (eye worm) DOMON domain-containing protein 0.0075 0.0306 0.0748
Loa Loa (eye worm) hypothetical protein 0.0051 0.0198 0.0485
Brugia malayi RNase H family protein 0.0023 0.0073 0.0178
Echinococcus multilocularis geminin 0.0331 0.144 0.1432
Entamoeba histolytica acetyltransferase, GNAT family 0.0029 0.0101 0.3546
Trichomonas vaginalis alpha-glucosidase, putative 0.0008 0.0006 0.0043
Onchocerca volvulus 0.0025 0.0086 0.0194
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Loa Loa (eye worm) acetyltransferase 0.0107 0.0446 0.1091
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0082 0.0662
Brugia malayi Zinc finger, C2H2 type family protein 0.0584 0.2561 0.6261
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.0031 0.0112 0.0873
Loa Loa (eye worm) hypothetical protein 0.0016 0.0045 0.011
Trichomonas vaginalis esterase, putative 0.0025 0.0086 0.0665
Loa Loa (eye worm) hypothetical protein 0.0237 0.1022 0.2498
Loa Loa (eye worm) Wnt2 protein 0.0016 0.0045 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0071
Onchocerca volvulus 0.0008 0.001 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0082 0.0913
Onchocerca volvulus 0.0008 0.001 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.012 0.0507 0.0504
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0102 0.0099
Echinococcus multilocularis serotonin transporter 0.0929 0.4091 0.4085
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0038 0.0143 0.0133
Onchocerca volvulus 0.0008 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Echinococcus granulosus GPCR family 2 0.0086 0.0356 0.0347
Brugia malayi ecdysteroid receptor 0.0051 0.0198 0.0484
Trypanosoma cruzi ribonuclease H1, putative 0.0023 0.0073 0.081
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.012 0.0507 0.0497
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.012 0.0507 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0071
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0008 0.001 0.0121
Brugia malayi Glycosyl hydrolases family 31 protein 0.0008 0.0006 0.0015
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.012 0.0507 0.1238
Echinococcus granulosus neuropeptide s receptor 0.0704 0.3093 0.3087
Onchocerca volvulus Ribonuclease H1 homolog 0.0023 0.0073 0.0163
Brugia malayi hypothetical protein 0.0238 0.1027 0.251
Schistosoma mansoni pcd6 interacting protein-related 0.0008 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0051 0.0198 0.0485
Echinococcus granulosus lamin dm0 0.0037 0.0137 0.0128
Trichomonas vaginalis set domain proteins, putative 0.0294 0.1276 1
Plasmodium falciparum amino acid transporter, putative 0.0158 0.0672 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.0507 0.0497
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0158 0.0672 0.067
Loa Loa (eye worm) follicle stimulating hormone receptor 0.031 0.1348 0.3295
Echinococcus multilocularis Polycystic kidney disease protein 0.0012 0.0025 0.0015
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0045 0.0171 0.1999
Schistosoma mansoni cellular tumor antigen P53 0.0062 0.0247 0.0245
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.003 0.0105 0.1196
Echinococcus granulosus tumor protein p63 0.0423 0.1846 0.1838
Mycobacterium leprae PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN 0.0091 0.0378 1
Brugia malayi Intermediate filament tail domain containing protein 0.0037 0.0137 0.0335
Echinococcus multilocularis beta LACTamase domain containing family member 0.0025 0.0086 0.0076
Brugia malayi Doublecortin family protein 0.0012 0.0025 0.006
Echinococcus granulosus beta LACTamase domain containing family member 0.0025 0.0086 0.0076
Schistosoma mansoni sodium/chloride dependent transporter 0.0929 0.4091 0.4089
Loa Loa (eye worm) hypothetical protein 0.0051 0.0198 0.0485
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0059 0.0453
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0083 0.0342 0.4759
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1468 0.6476 0.6473
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0031 0.0112 0.1368
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0078 0.032 0.0783
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.001 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0008 0.001 0.0024
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0024 0.0207
Plasmodium vivax glutathione reductase, putative 0.0033 0.0119 0.1465
Brugia malayi MH2 domain containing protein 0.0162 0.0691 0.1689
Onchocerca volvulus 0.0012 0.0025 0.0045
Schistosoma mansoni neuropeptide f receptor 76f 0.012 0.0507 0.0504
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0079 0.007
Loa Loa (eye worm) G-protein coupled receptor 0.012 0.0507 0.1238
Mycobacterium tuberculosis Conserved protein 0.0025 0.0086 0.093
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0024 0.0207
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.003 0.0104 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0055 0.0422
Schistosoma mansoni hypothetical protein 0.0055 0.0218 0.0216
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Echinococcus granulosus tyrosine protein kinase ABL1 0.0142 0.0603 0.0594
Entamoeba histolytica hypothetical protein 0.0067 0.0272 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0046 0.0178 0.1389
Loa Loa (eye worm) isocitrate dehydrogenase 0.003 0.0104 0.0255
Echinococcus granulosus neuropeptide Y receptor 0.012 0.0507 0.0497
Onchocerca volvulus 0.0018 0.0055 0.0118
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0008 0.001 0.0039
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0392 0.1712 0.4185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0071 0.0551
Echinococcus granulosus neuropeptides capa receptor 0.012 0.0507 0.0497
Loa Loa (eye worm) hypothetical protein 0.0187 0.0801 0.1958
Brugia malayi nuclear receptor RXR 0.0024 0.0079 0.0194
Onchocerca volvulus 0.0008 0.001 0.0008
Echinococcus granulosus neutral alpha glucosidase AB 0.002 0.0063 0.0053
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0198 0.0189
Brugia malayi Cytochrome P450 family protein 0.0073 0.0296 0.0723
Brugia malayi Tyrosine-protein kinase abl-1 0.0058 0.023 0.0562
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0198 0.0196
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0184 0.0787 0.0778
Echinococcus multilocularis lamin 0.0037 0.0137 0.0128
Echinococcus multilocularis lamin dm0 0.0037 0.0137 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0198 0.0484
Schistosoma mansoni hypothetical protein 0.0086 0.0356 0.0354
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Brugia malayi Thioredoxin reductase 0.0033 0.0119 0.0289
Loa Loa (eye worm) hypothetical protein 0.0158 0.0672 0.1643
Mycobacterium leprae putative cytochrome p450 0.002 0.006 0.0177
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.003 0.0105 0.1196
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.002 0.006 0.042
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0008 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0175 0.0428
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0158 0.0672 0.1643
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.002 0.001
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0079 0.0194
Echinococcus multilocularis musashi 0.0037 0.0137 0.0128
Brugia malayi follicle stimulating hormone receptor 0.031 0.1348 0.3295
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0018 0.0055 0.0045
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0158 0.0672 0.067
Schistosoma mansoni inositol monophosphatase 0.0046 0.0178 0.0176
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.012 0.0507 0.1238
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0198 0.0484
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0091 0.0378 0.5294
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0184 0.0787 0.0785
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.006 0.0553
Echinococcus multilocularis alpha 1A adrenergic receptor 0.012 0.0507 0.0497
Echinococcus granulosus lamin 0.0037 0.0137 0.0128
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.002 0.006 0.042
Loa Loa (eye worm) intermediate filament protein 0.0037 0.0137 0.0336
Brugia malayi nuclear receptor NHR-67 0.0024 0.0079 0.0194
Onchocerca volvulus 0.0037 0.0136 0.0317
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0019 0.0045
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.0175 0.234
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.0507 0.0504
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.001 0.0019 0.0009
Schistosoma mansoni amine GPCR 0.012 0.0507 0.0504
Loa Loa (eye worm) hypothetical protein 0.0237 0.1022 0.2498
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.006 0.0553
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.0507 0.0497
Echinococcus multilocularis microtubule associated protein 2 0.0867 0.3815 0.3809
Mycobacterium tuberculosis Probable transcriptional regulatory protein (probably LuxR/UhpA-family) 0.0091 0.0378 0.5294
Brugia malayi hypothetical protein 0.0008 0.001 0.0023
Brugia malayi Serotonin receptor 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0071
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0024 0.0078 0.087
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0198 0.0189
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.006 0.0656
Onchocerca volvulus 0.012 0.0507 0.1225
Loa Loa (eye worm) hypothetical protein 0.0036 0.0134 0.0328
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.014 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0051 0.0394
Echinococcus granulosus histone lysine methyltransferase setb 0.0038 0.014 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0102 0.0791
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0018 0.0055 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0044 0.034
Loa Loa (eye worm) CXXC zinc finger family protein 0.0037 0.0136 0.0332
Toxoplasma gondii LsmAD domain-containing protein 0.0046 0.0175 0.2217
Brugia malayi Serotonin receptor 0.012 0.0507 0.1238
Loa Loa (eye worm) latrophilin receptor protein 2 0.0086 0.0356 0.0871
Schistosoma mansoni dopamine-beta-monooxygenase 0.0743 0.3265 0.3264
Onchocerca volvulus 0.0008 0.001 0.0008
Echinococcus granulosus 7tm_1 domain containing protein 0.012 0.0507 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0044 0.034
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0105 0.0256
Echinococcus granulosus aryl hydrocarbon receptor 0.0018 0.0055 0.0045
Trypanosoma cruzi ribonuclease H1, putative 0.0023 0.0073 0.081
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0079 0.0194
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Onchocerca volvulus 0.007 0.0282 0.0674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0052 0.04
Toxoplasma gondii histone lysine methyltransferase SET1 0.0073 0.0299 0.3788
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0092 0.0379 0.452
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0029 0.0102 0.1158
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0082 0.0914
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.0198 0.0484
Schistosoma mansoni wnt-5 0.0016 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.002 0.006 0.042
Echinococcus multilocularis ribonuclease H1 0.0023 0.0073 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0038 0.014 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0198 0.0484
Mycobacterium leprae Probable lipase LipE 0.0025 0.0086 0.0958
Echinococcus granulosus neuropeptide FF receptor 2 0.012 0.0507 0.0497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.0507 0.0504
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0041 0.0157 0.199
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0079 0.0077
Brugia malayi hypothetical protein 0.0024 0.0079 0.0194
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0092 0.0083
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0055 0.0422
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0082 0.02
Loa Loa (eye worm) hypothetical protein 0.0055 0.0218 0.0534
Leishmania major hypothetical protein, conserved 0.0046 0.0175 0.205
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0011 0.0024 0.0207
Brugia malayi Smad1 0.0011 0.0022 0.0053
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.012 0.0507 0.0497
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.002 0.006 0.042
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.003 0.0105 0.1196
Schistosoma mansoni aldehyde dehydrogenase 0.0038 0.0143 0.0141
Schistosoma mansoni hypothetical protein 0.012 0.0507 0.0504
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0046 0.0178 0.2084
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.002 0.006 0.042
Echinococcus granulosus caspase 2 0.0055 0.0218 0.0209
Brugia malayi hypothetical protein 0.0158 0.0672 0.1643
Schistosoma mansoni nuclear receptor 0.0024 0.0079 0.0077
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0045 0.0171 0.1999
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.0198 0.0189
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0198 0.047
Schistosoma mansoni neuropeptide receptor 0.012 0.0507 0.0504
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Echinococcus multilocularis protein Wnt 2 0.0016 0.0045 0.0035
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0079 0.0194
Brugia malayi steroid hormone receptor 0.0051 0.0198 0.0484
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0158 0.0672 1
Schistosoma mansoni opsin-like receptor 0.012 0.0507 0.0504
Onchocerca volvulus 0.012 0.0507 0.1225
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0079 0.0179
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0011 0.0024 0.0287
Brugia malayi G-protein coupled receptor 0.012 0.0507 0.1238
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0086 0.0356 0.0347
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0046 0.0178 0.6459
Leishmania major trypanothione reductase 0.0033 0.0119 0.1361
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0079 0.007
Echinococcus granulosus transcription factor Dp 1 0.0026 0.0088 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0055 0.0422
Mycobacterium ulcerans lipase LipD 0.0025 0.0086 0.0707
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0078 0.0604
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.012 0.0507 0.1238
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.003 0.0105 0.3708
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0158 0.0672 0.0663
Trypanosoma brucei ingi protein (ORF1) 0.0024 0.0082 0.0913
Echinococcus granulosus histone acetyltransferase KAT2B 0.0031 0.0112 0.0103
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0162 0.0692 1
Schistosoma mansoni wnt related 0.0016 0.0045 0.0043
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0045 0.0171 0.0418
Onchocerca volvulus 0.012 0.0507 0.1225
Echinococcus multilocularis g protein coupled receptor 0.012 0.0507 0.0497
Schistosoma mansoni smad1 5 8 and 0.0011 0.0022 0.002
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.012 0.0507 0.1225
Onchocerca volvulus 0.012 0.0507 0.1225
Brugia malayi wnt family protein 0.0016 0.0045 0.011
Schistosoma mansoni phosphoglucomutase 0.0023 0.0073 0.0071
Toxoplasma gondii ribonuclease HI protein 0.0023 0.0073 0.0918
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.012 0.0507 0.0504
Brugia malayi RNase H family protein 0.0023 0.0073 0.0178
Onchocerca volvulus 0.0008 0.001 0.0008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.012 0.0507 0.0497
Trypanosoma cruzi trypanothione reductase, putative 0.0011 0.0024 0.0207
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0018 0.0055 0.0482
Schistosoma mansoni neuropeptide F-like receptor 0.012 0.0507 0.0504
Echinococcus granulosus histone acetyltransferase KAT2B 0.0104 0.0433 0.0424
Schistosoma mansoni sodium-dependent amino acid transporter 0.0158 0.0672 0.067
Loa Loa (eye worm) hypothetical protein 0.0051 0.0198 0.0485
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.0051 0.0198 0.0485
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Schistosoma mansoni hypothetical protein 0.0523 0.2288 0.2287
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.003 0.0104 0.0095
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.003 0.0104 0.119
Brugia malayi neuropeptide F receptor 0.012 0.0507 0.1238
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Loa Loa (eye worm) DOMON domain-containing protein 0.0075 0.0306 0.0748
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0078 0.032 0.0311
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0079 0.007
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0008 0.0006 0.0043
Schistosoma mansoni amine GPCR 0.012 0.0507 0.0504
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Brugia malayi acetyltransferase, GNAT family protein 0.0107 0.0446 0.109
Schistosoma mansoni hypothetical protein 0.0085 0.0348 0.0346
Echinococcus multilocularis fmrfamide receptor 0.012 0.0507 0.0497
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.012 0.0507 0.0497
Echinococcus granulosus lysosomal alpha glucosidase 0.0091 0.0376 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0071 0.0551
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0198 0.0485
Echinococcus granulosus Protein Wnt-11b 0.0016 0.0045 0.0035
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0051 0.0394
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Brugia malayi hypothetical protein 0.0055 0.0218 0.0533
Plasmodium falciparum histone acetyltransferase GCN5 0.0029 0.0101 0.1189
Brugia malayi Protein-tyrosine phosphatase 1 0.0008 0.001 0.0023
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0019 0.0056 0.0601
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0198 0.0189
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0079 0.0194
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0325 0.1414 0.3456
Brugia malayi MH2 domain containing protein 0.0011 0.0022 0.0053
Trichomonas vaginalis alpha-glucosidase, putative 0.0008 0.0006 0.0043
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0018 0.0055 0.0134
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0107 0.0446 0.0444
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0018 0.0052 0.0043
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0031 0.0112 0.1416
Schistosoma mansoni amine GPCR 0.012 0.0507 0.0504
Loa Loa (eye worm) melatonin receptor type 1A 0.012 0.0507 0.1238
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0086 0.0665
Schistosoma mansoni protein tyrosine phosphatase 0.0008 0.001 0.0007
Loa Loa (eye worm) cytochrome P450 family protein 0.0073 0.0296 0.0723
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Echinococcus granulosus sodium and chloride dependent glycine 0.0158 0.0672 0.0663
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0392 0.1712 0.4185
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0008 0.001 0.0007
Plasmodium falciparum glutathione reductase 0.0033 0.0119 0.1465
Schistosoma mansoni lamin 0.0037 0.0137 0.0135
Schistosoma mansoni rab6-interacting 0.0012 0.0025 0.0022
Onchocerca volvulus 0.012 0.0507 0.1225
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0325 0.1414 0.1412
Echinococcus granulosus g protein coupled receptor 0.012 0.0507 0.0497
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0038 0.0143 0.1659
Brugia malayi beta-lactamase 0.0025 0.0086 0.0209
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0198 0.047
Echinococcus granulosus neuropeptide receptor 0.012 0.0507 0.0497
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.014 0.0138
Schistosoma mansoni neuropeptide receptor 0.012 0.0507 0.0504
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0031 0.0112 0.1416
Schistosoma mansoni rab6-interacting 0.0012 0.0025 0.0022
Echinococcus granulosus dro:myosuppressin receptor 0.012 0.0507 0.0497
Treponema pallidum ribonuclease H (rnhA) 0.0023 0.0073 0.0122
Loa Loa (eye worm) protein tyrosine phosphatase 0.0008 0.001 0.0024
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0079 0.0194
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0008 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Schistosoma mansoni alpha-glucosidase 0.0078 0.032 0.0318
Echinococcus granulosus survival motor neuron protein 1 0.0342 0.1487 0.1479
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0071 0.0551
Toxoplasma gondii target of rapamycin (TOR), putative 0.0022 0.0071 0.0893
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0142 0.0603 0.0594
Onchocerca volvulus 0.0025 0.0086 0.0194
Brugia malayi hypothetical protein 0.0012 0.0025 0.006
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.002 0.006 0.042
Onchocerca volvulus 0.0008 0.001 0.0008
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.012 0.0507 0.0497
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0029 0.0102 0.1158
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.006 0.0553
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.002 0.006 0.042
Echinococcus granulosus cpg binding protein 0.0039 0.0145 0.0135
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Mycobacterium tuberculosis Probable lipase LipD 0.0025 0.0086 0.093
Loa Loa (eye worm) glutaminase 2 0.021 0.0903 0.2207
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0025 0.0086 0.093
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0063 0.0483
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0025 0.0086 0.093
Schistosoma mansoni peptidylglycine monooxygenase 0.0392 0.1712 0.171
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0198 0.0196
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0046 0.0178 1
Loa Loa (eye worm) glutathione reductase 0.0033 0.0119 0.029
Echinococcus multilocularis serotonin receptor 0.012 0.0507 0.0497
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.012 0.0507 0.0497
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Trichomonas vaginalis adenylate cyclase, putative 0.0018 0.0055 0.0422
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.0507 0.0504
Plasmodium vivax ataxin-2 like protein, putative 0.0046 0.0175 0.234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0071 0.0551
Toxoplasma gondii hypothetical protein 0.0158 0.0672 0.8536
Onchocerca volvulus 4.1 G protein, putative homolog 0.0008 0.001 0.0008
Mycobacterium ulcerans beta-lactamase 0.0025 0.0086 0.0707
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.0175 0.205
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0025 0.0086 0.0209
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0024 0.0207
Schistosoma mansoni biogenic amine receptor 0.012 0.0507 0.0504
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.002 0.006 0.042
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0029 0.002
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0029 0.002
Trypanosoma brucei ingi protein (ORF1) 0.0024 0.0082 0.0913
Echinococcus granulosus g protein coupled receptor 0.012 0.0507 0.0497
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.006 0.0553
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0198 0.0189
Echinococcus granulosus microtubule associated protein 2 0.0867 0.3815 0.3809
Echinococcus multilocularis mothers against decapentaplegic 5 0.0011 0.0022 0.0012
Brugia malayi hypothetical protein 0.0024 0.0079 0.0194
Schistosoma mansoni alpha-glucosidase 0.0078 0.032 0.0318
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.001 0.0017 0.0132
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.003 0.0104 0.119
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0079 0.0179
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0092 0.0225
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.0507 0.0497
Echinococcus granulosus TGF beta signal transducer SmadC 0.0011 0.0022 0.0012
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Toxoplasma gondii thioredoxin reductase 0.0033 0.0119 0.1495
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0055 0.0422
Brugia malayi nuclear receptor RXR 0.0027 0.0092 0.0225
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0011 0.0024 0.0021
Schistosoma mansoni hypothetical protein 0.0086 0.0356 0.0354
Loa Loa (eye worm) hypothetical protein 0.0055 0.0218 0.0534
Mycobacterium tuberculosis Conserved hypothetical protein 0.0102 0.0424 0.5995
Loa Loa (eye worm) neuropeptide F receptor 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.0158 0.0672 0.1643
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.002 0.006 0.042
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0031 0.0112 0.0873
Loa Loa (eye worm) hypothetical protein 0.0086 0.0356 0.0871
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0086 0.0962
Mycobacterium ulcerans putative regulatory protein 0.0052 0.0206 0.207
Loa Loa (eye worm) protein-tyrosine phosphatase 0.001 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0027 0.0092 0.0225
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.0507 0.0497
Echinococcus granulosus Smad4 0.0011 0.0022 0.0012
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0119 0.1361
Onchocerca volvulus 0.012 0.0507 0.1225
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.006 0.0553
Brugia malayi hypothetical protein 0.0342 0.1487 0.3634
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Echinococcus granulosus dnaJ subfamily B 0.0523 0.2288 0.2281
Schistosoma mansoni transcription factor LCR-F1 0.0067 0.0272 0.027
Schistosoma mansoni hypothetical protein 0.0067 0.0272 0.027
Schistosoma mansoni peptide (allatostatin)-like receptor 0.012 0.0507 0.0504
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0158 0.0672 0.0663
Leishmania major protein kinase, putative 0.0019 0.0056 0.0601
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0158 0.0672 0.8536
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0094 0.1059
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.003 0.0104 0.121
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.012 0.0507 0.0497
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.012 0.0507 0.0497
Echinococcus multilocularis biogenic amine (5HT) receptor 0.012 0.0507 0.0497
Brugia malayi beta-lactamase family protein 0.0025 0.0086 0.0209
Loa Loa (eye worm) hypothetical protein 0.0017 0.0049 0.0121
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0079 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0198 0.0485
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.0507 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0078 0.0604
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Brugia malayi Cytochrome P450 family protein 0.0025 0.0082 0.0199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.0507 0.0504
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0198 0.0189
Schistosoma mansoni alpha-1 adrenergic receptor 0.012 0.0507 0.0504
Echinococcus granulosus ribonuclease H1 0.0023 0.0073 0.0064
Schistosoma mansoni nuclear receptor 0.0024 0.0079 0.0077
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0198 0.0196
Onchocerca volvulus 0.0038 0.014 0.0328
Loa Loa (eye worm) hypothetical protein 0.0054 0.0212 0.0519
Echinococcus multilocularis serotonin receptor 0.012 0.0507 0.0497
Echinococcus multilocularis allatostatin A receptor 0.012 0.0507 0.0497
Echinococcus granulosus Protein Wnt-111 0.0016 0.0045 0.0035
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0158 0.0672 0.1643
Trichomonas vaginalis alpha-glucosidase, putative 0.0008 0.0006 0.0043
Schistosoma mansoni coup transcription factor 0.0051 0.0198 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0044 0.0339
Loa Loa (eye worm) hypothetical protein 0.0342 0.1487 0.3635
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.003 0.0104 0.119
Loa Loa (eye worm) solute carrier family 6 member 4 0.0929 0.4091 1
Echinococcus granulosus biogenic amine 5HT receptor 0.012 0.0507 0.0497
Schistosoma mansoni microtubule-associated protein tau 0.0867 0.3815 0.3813
Toxoplasma gondii hypothetical protein 0.0158 0.0672 0.8536
Echinococcus granulosus lipoxygenase domain containing protein 0.0012 0.0025 0.0015
Brugia malayi Dopamine receptor protein 1 0.012 0.0507 0.1238
Echinococcus multilocularis g protein coupled receptor 0.012 0.0507 0.0497
Schistosoma mansoni amine GPCR 0.012 0.0507 0.0504
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Echinococcus granulosus intermediate filament protein 0.0037 0.0137 0.0128
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0091 0.0376 0.0919
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0038 0.0143 0.0133
Mycobacterium ulcerans aldehyde dehydrogenase 0.0038 0.0143 0.1359
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Brugia malayi beta-lactamase family protein 0.0025 0.0086 0.0209
Echinococcus granulosus geminin 0.0331 0.144 0.1432
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.0507 0.0497
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Mycobacterium ulcerans putative regulatory protein 0.0091 0.0378 0.4026
Onchocerca volvulus Huntingtin homolog 0.0237 0.1022 0.2486
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0017 0.0129
Echinococcus granulosus thyrotropin releasing hormone receptor 0.012 0.0507 0.0497
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.001 0.0019 0.0009
Onchocerca volvulus 0.012 0.0507 0.1225
Leishmania major phosphatidylinositol 3-related kinase, putative 0.001 0.0017 0.0132
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0392 0.1712 0.171
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0158 0.0672 0.8536
Onchocerca volvulus 0.0037 0.0137 0.032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0198 0.0189
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0158 0.0672 0.067
Trichomonas vaginalis guanylate cyclase, putative 0.0018 0.0055 0.0422
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Schistosoma mansoni histamine h1 receptor 0.012 0.0507 0.0504
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0198 0.0485
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0079 0.0194
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0134
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0078 0.032 0.0318
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0193 0.083 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0018 0.0052 0.0043
Echinococcus granulosus protein Wnt 2 0.0016 0.0045 0.0035
Mycobacterium tuberculosis Probable esterase LipL 0.0025 0.0086 0.093
Treponema pallidum sodium- and chloride- dependent transporter 0.0929 0.4091 1
Schistosoma mansoni microsomal glutathione s-transferase 0.0184 0.0787 0.0785
Schistosoma mansoni tyrosine kinase 0.014 0.0594 0.0592
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Onchocerca volvulus 0.0008 0.001 0.0008
Plasmodium falciparum thioredoxin reductase 0.0033 0.0119 0.1465
Brugia malayi Glycosyl hydrolases family 31 protein 0.002 0.0063 0.0152
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.001 0.0017 0.0008
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0024 0.0207
Echinococcus multilocularis transcription factor Dp 1 0.0026 0.0088 0.0078
Echinococcus granulosus Polycystic kidney disease protein 0.0012 0.0025 0.0015
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0008 0.001 0.0024
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.001 0.0017 0.0008
Brugia malayi Dopamine receptor 0.012 0.0507 0.1238
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0198 0.0484
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0008 0.001 0.0007
Brugia malayi RE15519p 0.012 0.0507 0.1238
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0075 0.0305 0.4205
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Echinococcus multilocularis cpg binding protein 0.0039 0.0145 0.0135
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0008 0.001 0.0007
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0025 0.0086 0.093
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.012 0.0507 0.0504
Loa Loa (eye worm) cytochrome P450 0.002 0.006 0.0148
Echinococcus granulosus serotonin transporter 0.0929 0.4091 0.4085
Trypanosoma brucei isocitrate dehydrogenase, putative 0.003 0.0104 0.119
Schistosoma mansoni phosphoglucomutase 0.0023 0.0073 0.0071
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.006 0.0553
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.003 0.0104 0.119
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Onchocerca volvulus 0.0024 0.0079 0.0179
Brugia malayi nuclear hormone receptor 0.0024 0.0079 0.0194
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0086 0.0959
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0008 0.001 0.0023
Schistosoma mansoni biogenic amine receptor 0.012 0.0507 0.0504
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.003 0.0104 0.1248
Echinococcus multilocularis neuropeptide Y receptor 0.012 0.0507 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0071
Onchocerca volvulus 0.0158 0.0672 0.163
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0063 0.0483
Echinococcus multilocularis neuropeptide FF receptor 2 0.012 0.0507 0.0497
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0092 0.0225
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.012 0.0507 0.0497
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0092 0.0083
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0024 0.0207
Schistosoma mansoni zinc finger protein 0.0024 0.0079 0.0077
Echinococcus granulosus alpha 1A adrenergic receptor 0.012 0.0507 0.0497
Trypanosoma brucei glucosidase, putative 0.002 0.0063 0.0681
Echinococcus multilocularis neuropeptide s receptor 0.0704 0.3093 0.3087
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0025 0.0086 0.0707
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0079 0.0194
Echinococcus multilocularis survival motor neuron protein 1 0.0342 0.1487 0.1479
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0198 0.0196
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0198 0.0189
Schistosoma mansoni cytochrome P450 0.002 0.006 0.0058
Brugia malayi putative neuropeptide receptor NPR1 0.012 0.0507 0.1238
Brugia malayi hypothetical protein 0.0008 0.001 0.0023
Brugia malayi glutaminase DH11.1 0.021 0.0903 0.2207
Brugia malayi Serotonin/octopamine receptor family protein 7 0.012 0.0507 0.1238
Onchocerca volvulus Cell death protein 3 homolog 0.0055 0.0218 0.0519
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0198 0.0484
Schistosoma mansoni lamin 0.0037 0.0137 0.0135
Echinococcus multilocularis g protein coupled receptor 0.012 0.0507 0.0497
Echinococcus multilocularis apoptotic protease activating factor 1 0.0055 0.0218 0.0209
Brugia malayi G-protein coupled receptor 0.012 0.0507 0.1238
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.006 0.0656
Leishmania major protein kinase, putative 0.0019 0.0056 0.0601
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.006 0.0553
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.002 0.0064 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0198 0.0485
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0083 0.0342 0.4759
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0158 0.0672 0.0663
Schistosoma mansoni caspase-7 (C14 family) 0.0055 0.0218 0.0216
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0008 0.001 0.0007
Brugia malayi isocitrate dehydrogenase 0.003 0.0104 0.0255
Onchocerca volvulus 0.0052 0.0206 0.0488
Onchocerca volvulus 0.0025 0.0086 0.0194
Leishmania major cytochrome p450-like protein 0.0025 0.0082 0.0914
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0029 0.0102 0.1158
Plasmodium falciparum LCCL domain-containing protein 0.0012 0.0025 0.0017
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0036 0.0131 0.0121
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Onchocerca volvulus 0.0053 0.0206 0.0489
Loa Loa (eye worm) DOMON domain-containing protein 0.0075 0.0306 0.0748
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0079 0.0077
Echinococcus granulosus peptide allatostatin:somatostatin 0.012 0.0507 0.0497
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0929 0.4091 1
Echinococcus granulosus RUN 0.0012 0.0025 0.0015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0086 0.0356 0.0347
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Echinococcus multilocularis sex peptide receptor 0.012 0.0507 0.0497
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.006 0.0553
Echinococcus granulosus neuropeptide Y receptor 0.012 0.0507 0.0497
Echinococcus multilocularis inositol monophosphatase 1 0.0046 0.0178 0.0169
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0158 0.0672 0.1643
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0019 0.0056 0.0601
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.003 0.0105 0.1196
Brugia malayi gonadotropin-releasing hormone receptor 2 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Mycobacterium ulcerans glutaminase 0.021 0.0903 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0045 0.0171 0.0169
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0063 0.0681
Echinococcus granulosus sodium and chloride dependent glycine 0.0158 0.0672 0.0663
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0033 0.012 0.1379
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.002 0.0063 0.0483
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0198 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0071
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.012 0.0507 0.0504
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.002 0.006 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0062 0.0476
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.002 0.0063 0.2112
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.003 0.0104 0.0102
Brugia malayi hypothetical protein 0.012 0.0507 0.1238
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0017 0.0129
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0086 0.0356 0.0347
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0037 0.0137 0.0336
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Echinococcus granulosus tachykinin peptides receptor 99D 0.012 0.0507 0.0497
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0158 0.0672 0.067
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.012 0.0507 0.0497
Schistosoma mansoni biogenic amine (dopamine) receptor 0.012 0.0507 0.0504
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0011 0.0024 0.0207
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0018 0.0055 0.0422
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0105 0.0816
Onchocerca volvulus 0.0008 0.001 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0024 0.0207
Echinococcus granulosus neuropeptide receptor A26 0.0704 0.3093 0.3087
Trichomonas vaginalis penicillin-binding protein, putative 0.0025 0.0086 0.0665
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0079 0.0077
Brugia malayi hypoxia-induced factor 1 0.0219 0.0945 0.231
Loa Loa (eye worm) phosphatidylinositol 3 0.001 0.0017 0.0042
Loa Loa (eye worm) hypoxia-induced factor 1 0.0219 0.0945 0.231
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0102 0.0791
Echinococcus multilocularis neuropeptide Y receptor 0.012 0.0507 0.0497
Echinococcus granulosus tm gpcr rhodopsin 0.012 0.0507 0.0497
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.012 0.0507 0.0497
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0024 0.0207
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0075 0.0305 0.4205
Onchocerca volvulus 0.0008 0.001 0.0008
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0008 0.001 0.0039
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.012 0.0507 0.0497
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.012 0.0507 0.1238
Onchocerca volvulus 0.0008 0.001 0.0008
Schistosoma mansoni biogenic amine receptor 0.012 0.0507 0.0504
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Echinococcus multilocularis protein Wnt 1 0.0016 0.0045 0.0035
Brugia malayi hypothetical protein 0.0067 0.0272 0.0665
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0022 0.0054
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0008 0.001 0.0007
Mycobacterium tuberculosis Conserved protein 0.0025 0.0086 0.093
Loa Loa (eye worm) beta-lactamase 0.0025 0.0086 0.0209
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0046 0.0178 0.2084
Schistosoma mansoni neuropeptide receptor 0.012 0.0507 0.0504
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0008 0.001 0.0023
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0029 0.0102 0.1158
Brugia malayi Wnt-4 protein precursor 0.0016 0.0045 0.011
Schistosoma mansoni hypothetical protein 0.0086 0.0356 0.0354
Plasmodium vivax thioredoxin reductase, putative 0.0033 0.0119 0.1465
Echinococcus multilocularis zinc finger transcription factor gli2 0.0584 0.2561 0.2554
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0019 0.0056 0.0601
Echinococcus granulosus tm gpcr rhodopsin 0.012 0.0507 0.0497
Echinococcus multilocularis g-protein coupled receptor 0.012 0.0507 0.0497
Echinococcus granulosus mitogen activated protein kinase 3 0.0029 0.0102 0.0092
Loa Loa (eye worm) phosphatidylinositol 3 0.003 0.0105 0.0257
Onchocerca volvulus 0.0008 0.001 0.0008
Echinococcus multilocularis tyrosine protein kinase Abl 0.0058 0.023 0.0221
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0198 0.0484
Loa Loa (eye worm) TK/ABL protein kinase 0.0142 0.0603 0.1474
Trichomonas vaginalis inositol monophosphatase, putative 0.0046 0.0178 0.1389
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0045 0.0171 0.0162
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Leishmania major tyrosine specific protein phosphatase, putative 0.0008 0.001 0.0039
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0045 0.0171 0.1999
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0198 0.0484
Echinococcus multilocularis caspase 2 0.0055 0.0218 0.0209
Brugia malayi hypothetical protein 0.0061 0.0244 0.0596
Trypanosoma brucei trypanothione reductase 0.0033 0.0119 0.1361
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0024 0.0207
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0092 0.009
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.003 0.0105 0.1196
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.012 0.0507 0.1238
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0018 0.0055 0.0422
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Loa Loa (eye worm) Smad1 0.0011 0.0022 0.0054
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0027 0.0094 0.1059
Toxoplasma gondii NADPH-glutathione reductase 0.0011 0.0024 0.0287
Onchocerca volvulus 0.0008 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0051 0.0198 0.0485
Brugia malayi conserved hypotetical protein 0.0024 0.0079 0.0194
Brugia malayi Inositol-1 0.0046 0.0178 0.0435
Loa Loa (eye worm) hypothetical protein 0.0024 0.0079 0.0194
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0018 0.0055 0.0587
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0008 0.001 0.0024
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0158 0.0672 0.8536
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0079 0.0324 0.0322
Onchocerca volvulus 0.0008 0.001 0.0008
Echinococcus multilocularis neuropeptide receptor A26 0.0704 0.3093 0.3087
Brugia malayi larval opioid receptor 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0024
Onchocerca volvulus 0.0062 0.0247 0.059
Echinococcus multilocularis rhodopsin orphan GPCR 0.012 0.0507 0.0497
Echinococcus multilocularis neuropeptide receptor 0.012 0.0507 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0052 0.04
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Loa Loa (eye worm) hypothetical protein 0.012 0.0507 0.1238
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0029 0.0102 0.1158
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0046 0.0178 0.2084
Mycobacterium tuberculosis Possible transcriptional regulatory protein 0.0091 0.0378 0.5294
Schistosoma mansoni hypothetical protein 0.0086 0.0356 0.0354
Mycobacterium ulcerans aldehyde dehydrogenase 0.0038 0.0143 0.1359
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0079 0.007
Brugia malayi cytochrome P450 0.002 0.006 0.0147
Schistosoma mansoni single-minded 0.0071 0.0287 0.0285
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.002 0.006 0.042
Loa Loa (eye worm) hypothetical protein 0.0016 0.0045 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.012 0.0507 0.0504
Mycobacterium tuberculosis Probable hydrolase 0.0025 0.0086 0.093
Schistosoma mansoni Smad4 0.0011 0.0022 0.002
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0011 0.0022 0.002
Schistosoma mansoni hypothetical protein 0.002 0.006 0.0058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0024 0.0207
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0158 0.0672 0.0663

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 0.86 nM The binding affinity towards Gonadotropin-releasing hormone receptor ChEMBL. 1280300
Potency (functional) = 0.36 In vitro antagonistic potency relative to Ac-delta3Pro1-(D)Fpa2-(D)Trp3,6]GnRH ChEMBL. 1280300

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.