Detailed information for compound 1996784

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 485.889 | Formula: C24H19ClF3N5O
  • H donors: 3 H acceptors: 3 LogP: 5.22 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=O)c1cc(NCc2ccccc2)cc2c1ncnc2NCc1ccc(c(c1)C(F)(F)F)Cl
  • InChi: 1S/C24H19ClF3N5O/c25-20-7-6-15(8-19(20)24(26,27)28)12-31-23-18-10-16(30-11-14-4-2-1-3-5-14)9-17(22(29)34)21(18)32-13-33-23/h1-10,13,30H,11-12H2,(H2,29,34)(H,31,32,33)
  • InChiKey: IWGYPGXQFYEHLX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aurora kinase A Starlite/ChEMBL No references
Homo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Entamoeba histolytica protein kinase 2, putative Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus granulosus aurora kinase A Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma congolense aurora B kinase Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma japonicum RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium yoelii kinase Akt/PKB-related Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium vivax serine/threonine protein kinase 6, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma cruzi Protein kinase B Get druggable targets OG5_126635 All targets in OG5_126635
Toxoplasma gondii AGC kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica serine/threonine- protein kinase 6, putative Get druggable targets OG5_127024 All targets in OG5_127024
Cryptosporidium parvum protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium berghei rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania braziliensis protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma brucei gambiense rac serine-threonine kinase, putative,protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) AUR protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus calcium:calmodulin dependent protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans likely protein kinase similar to S. cerevisiae YPK2 (YMR104C) Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei aurora B kinase Get druggable targets OG5_127024 All targets in OG5_127024
Neospora caninum hypothetical protein Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania donovani Aurora I-related kinase Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma cruzi aurora B kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase , putative Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium vivax rac-beta serine/threonine protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi p70 ribosomal S6 kinase beta Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium yoelii putative protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium knowlesi RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma brucei gambiense protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus granulosus serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad Get druggable targets OG5_126635 All targets in OG5_126635
Loa Loa (eye worm) AUR protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica serine/threonine- protein kinase 6 , putative Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma japonicum Sodium/potassium-transporting ATPase subunit beta-1, putative Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K04456 RAC serine/threonine-protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus multilocularis nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K07390 monothiol glutaredoxin, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi serine/threonine protein kinase 6 Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trypanosoma congolense rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Toxoplasma gondii aurora kinase Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium knowlesi serine/threonine protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus multilocularis Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Candida albicans likely protein kinase similar to S. cerevisiae IPL1 (YPL209C) Aurora protein kinase involved in regulating kinetochore-microtubu Get druggable targets OG5_127024 All targets in OG5_127024
Giardia lamblia Aurora kinase Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus serine threonine protein kinase nrc Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis aurora kinase A Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma japonicum ko:K08792 serum/glucocorticoid regulated kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis serine:threonine protein kinase 12 B Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania infantum protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma cruzi rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus Glutaredoxin protein 5 Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus nervana 2 Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium falciparum serine/threonine protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Neospora caninum Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1), related Get druggable targets OG5_126635 All targets in OG5_126635
Plasmodium berghei serine/threonine protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) AGC/RSK/P70 protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium falciparum RAC-beta serine/threonine protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus granulosus serine:threonine protein kinase 12 B Get druggable targets OG5_127024 All targets in OG5_127024
Candida albicans protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Giardia lamblia Kinase, AGC PKA Get druggable targets OG5_126635 All targets in OG5_126635
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Echinococcus multilocularis rac serine:threonine kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica serine/threonine protein kinase 6, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma brucei rac serine-threonine kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum Serine/threonine-protein kinase 12, putative Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) AGC/AKT protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Leishmania major protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Candida albicans likely protein kinase similar to S. cerevisiae IPL1 (YPL209C) Aurora protein kinase involved in regulating kinetochore-microtubu Get druggable targets OG5_127024 All targets in OG5_127024
Brugia malayi serine/threonine-protein kinase 6 Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Entamoeba histolytica PH domain containing protein kinase, putative Get druggable targets OG5_126635 All targets in OG5_126635
Cryptosporidium hominis protein kinase (EC 2.7.1.-) p46XlEg22 Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) AUR protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus granulosus sodium:potassium dependent atpase beta subunit Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma japonicum ko:K08850 aurora kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania mexicana protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma mansoni serine/threonine-protein kinase Get druggable targets OG5_126635 All targets in OG5_126635
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Brugia malayi serine/threonine kinase 12 Get druggable targets OG5_127024 All targets in OG5_127024
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tyrosine kinase 0.0088 0.0332 0.0446
Onchocerca volvulus 0.0054 0.0169 0.0577
Echinococcus granulosus zinc finger protein 0.003 0.0052 0.0063
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0027 0.0038 0.0038
Echinococcus multilocularis epidermal growth factor receptor 0.0419 0.1915 0.2609
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0064 0.0218 0.029
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0067 0.0262
Schistosoma mansoni nephrin 0.0031 0.006 0.0068
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0076 0.0276 0.0819
Loa Loa (eye worm) hypothetical protein 0.0038 0.0094 0.0094
Brugia malayi protein-tyrosine kinase 0.0088 0.0332 0.0989
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0112 0.0392
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0091 0.0347 0.0467
Loa Loa (eye worm) hypothetical protein 0.0044 0.0123 0.0123
Echinococcus granulosus methyl CpG binding domain protein 2 0.0023 0.0021 0.002
Loa Loa (eye worm) TOPoisomerase family member 0.0192 0.0829 0.0829
Entamoeba histolytica hypothetical protein 0.0035 0.0078 0.0273
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0009 0.0012
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0039 0.0097 0.0278
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0019 0.0018
Schistosoma mansoni inositol monophosphatase 0.0069 0.0241 0.0308
Brugia malayi Raf kinase 0.0218 0.0955 0.2869
Echinococcus multilocularis cyclins 0.0048 0.0138 0.0181
Schistosoma mansoni hypothetical protein 0.03 0.1348 0.1779
Echinococcus multilocularis serine:threonine protein kinase N2 0.0035 0.0076 0.0096
Echinococcus granulosus twitchin 0.0033 0.0069 0.0087
Schistosoma mansoni tyrosine kinase 0.0099 0.0384 0.0498
Echinococcus multilocularis neuroglian 0.0023 0.0019 0.0018
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0032 0.0068
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0052 0.0158 0.0208
Loa Loa (eye worm) RhoGAP domain-containing protein 0.003 0.0054 0.0054
Echinococcus granulosus protein kinase c epsilon type 0.0049 0.0144 0.0188
Onchocerca volvulus 0.0073 0.0258 0.0902
Echinococcus multilocularis L aminoadipate semialdehyde 0.0031 0.006 0.0074
Leishmania major hypothetical protein, conserved 0.0022 0.0015 0.0016
Schistosoma mansoni cell adhesion molecule 0.0023 0.0019 0.0013
Plasmodium falciparum glycogen synthase kinase 3 0.0054 0.0169 0.0759
Onchocerca volvulus 0.0031 0.006 0.0185
Schistosoma mansoni jumonji/arid domain-containing protein 0.0172 0.0734 0.0964
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0055 0.0204
Loa Loa (eye worm) hypothetical protein 0.0064 0.0218 0.0218
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0712 0.3317 0.3317
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.0001
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0448 0.2053 0.6182
Brugia malayi Protein kinase domain containing protein 0.0035 0.0076 0.0214
Brugia malayi jmjC domain containing protein 0.0044 0.0123 0.0356
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0069 0.0241 0.1113
Echinococcus granulosus dnaJ subfamily B 0.0365 0.1658 0.2257
Echinococcus granulosus serine threonine protein kinase nrc 0.0061 0.02 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0066 0.0215
Brugia malayi jmjC domain containing protein 0.0044 0.0123 0.0356
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.0189 0.1378
Brugia malayi PHD-finger family protein 0.0037 0.0086 0.0245
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0117 0.0468 0.0632
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0061 0.0201 0.1476
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0022 0.0044
Giardia lamblia Fructose-bisphosphate aldolase 0.0395 0.1802 1
Mycobacterium ulcerans DNA gyrase subunit A 0.0286 0.128 1
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0022 0.0015 0.0012
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0166 0.0219
Loa Loa (eye worm) phosphofructokinase 0.0147 0.0614 0.0614
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0566 0.2617 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.1802 0.6873
Echinococcus granulosus transcription factor Dp 1 0.0086 0.0321 0.0431
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0035 0.0076 0.0076
Echinococcus granulosus casein kinase ii subunit beta 0.0071 0.0252 0.0337
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0015 0.0004
Trichomonas vaginalis AGC family protein kinase 0.013 0.0531 0.1997
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0031 0.006 0.0165
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0016
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0034 0.0071 0.0089
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0046 0.0046
Entamoeba histolytica protein kinase , putative 0.013 0.0531 0.2007
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0035 0.0076 0.0096
Schistosoma mansoni serine/threonine kinase 0.0035 0.0076 0.0089
Trichomonas vaginalis rotamase, putative 0.0032 0.0063 0.0201
Echinococcus granulosus bloom syndrome protein 0.0092 0.0353 0.0474
Echinococcus multilocularis aldo keto reductase 0.0091 0.0347 0.0467
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.017 0.1227
Brugia malayi aspartic protease BmAsp-1, identical 0.0022 0.0014 0.0027
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0069 0.0241 0.1787
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0022 0.0014 0.0014
Toxoplasma gondii NADPH-glutathione reductase 0.0061 0.0201 0.092
Loa Loa (eye worm) hypothetical protein 0.0044 0.0123 0.0123
Trypanosoma brucei carbonic anhydrase-like protein 0.0712 0.3317 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0112
Toxoplasma gondii AGC kinase 0.0088 0.0329 0.1548
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0144 0.0514
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0046 0.016
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0023 0.0019 0.0018
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0091 0.0347 0.1022
Echinococcus multilocularis microtubule associated protein 2 0.155 0.7325 1
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0348 0.1295
Loa Loa (eye worm) hypothetical protein 0.0069 0.024 0.024
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.002 0.002
Schistosoma mansoni carbonic anhydrase-related 0.0448 0.2053 0.2717
Echinococcus granulosus tyrosine protein kinase Fyn 0.0099 0.0384 0.0516
Brugia malayi Csnk2b protein 0.0071 0.0252 0.0747
Schistosoma mansoni cpg binding protein 0.0059 0.0194 0.0246
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0024
Loa Loa (eye worm) AUR protein kinase 0.013 0.0531 0.0531
Loa Loa (eye worm) TK/FAK protein kinase 0.0264 0.1173 0.1173
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0046 0.0056
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0023 0.0019 0.0018
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0395 0.1802 0.6877
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0112 0.0325
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0076 0.0273 0.0798
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0214 0.0932 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0023 0.0023 0.0059
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0049 0.0144 0.0514
Loa Loa (eye worm) hypothetical protein 0.0055 0.0172 0.0172
Echinococcus granulosus glutathione S transferase Mu 1 0.0023 0.0021 0.0021
Brugia malayi chromobox protein homolog 3 0.0038 0.0093 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0138 0.0491
Treponema pallidum fructose-bisphosphate aldolase 0.0395 0.1802 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.022 0.0965 0.131
Loa Loa (eye worm) TK protein kinase 0.0023 0.002 0.002
Trypanosoma brucei protein kinase, putative 0.0023 0.002 0.0032
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0061 0.0201 0.1476
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0032 0.0121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.1802 0.6873
Schistosoma mansoni cell adhesion molecule 0.0033 0.007 0.0081
Schistosoma mansoni protein kinase 0.0138 0.057 0.0746
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.003 0.0054 0.0066
Giardia lamblia Kinase, AGC PKA 0.0061 0.02 0.1059
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0504 0.0658
Giardia lamblia Kinase, CMGC GSK 0.0054 0.0169 0.0884
Toxoplasma gondii histone lysine methyltransferase SET1 0.0106 0.0417 0.1979
Brugia malayi Phosphoglycerate kinase 0.0061 0.0202 0.0595
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0112 0.031
Echinococcus granulosus ephrin type A receptor 4 A 0.0081 0.0299 0.0401
Trichomonas vaginalis mercuric reductase, putative 0.0061 0.0201 0.0733
Echinococcus multilocularis serine threonine protein kinase 0.0035 0.0076 0.0096
Loa Loa (eye worm) hypothetical protein 0.0119 0.048 0.048
Leishmania major phosphotransferase, putative 0.0065 0.0222 0.0643
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0705 0.0925
Loa Loa (eye worm) hypothetical protein 0.0073 0.0258 0.0258
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0022 0.0015 0.0015
Trypanosoma brucei unspecified product 0.0071 0.0251 0.0732
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.005 0.015 0.0424
Schistosoma mansoni nephrin 0.0023 0.0019 0.0013
Trypanosoma brucei aldo/keto reductase, putative 0.0026 0.0037 0.0083
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0022 0.0014 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0352 0.1596 0.1596
Brugia malayi Bloom's syndrome protein homolog 0.0092 0.0353 0.105
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.0015 0.0029
Plasmodium vivax aspartyl protease, putative 0.0022 0.0014 0.0077
Trypanosoma cruzi CYC2-like cyclin, putative 0.009 0.0341 0.1003
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0045 0.0053
Trypanosoma brucei glucosidase, putative 0.0049 0.0144 0.0408
Schistosoma mansoni loxhd1 0.0038 0.0094 0.0114
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0112 0.0851
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0015 0.0016
Echinococcus granulosus voltage gated potassium channel subunit 0.0026 0.0037 0.0043
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0712 0.3317 0.4397
Echinococcus multilocularis mitogen activated protein kinase 3 0.0076 0.0273 0.0365
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0055 0.0174 0.1333
Echinococcus multilocularis cyclins 0.0048 0.0138 0.0181
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0061 0.0201 0.058
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0035 0.0076 0.0096
Brugia malayi cell division control protein 2 homolog 0.0049 0.0146 0.0425
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0079
Plasmodium vivax plasmepsin IV, putative 0.0022 0.0014 0.0077
Entamoeba histolytica protein kinase, putative 0.0054 0.0169 0.0619
Echinococcus granulosus protein kinase C gamma type 0.0035 0.0076 0.0096
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0193 0.0835 0.2497
Brugia malayi Protein kinase domain containing protein 0.0031 0.006 0.0166
Giardia lamblia Kinase, CMGC CDK 0.0049 0.0146 0.0756
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0609 0.2296
Plasmodium vivax glutathione reductase, putative 0.0216 0.0942 0.735
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0026 0.0065
Trichomonas vaginalis cyclins, putative 0.009 0.0341 0.1269
Schistosoma mansoni glutamate synthase 0.0022 0.0015 0.0008
Schistosoma mansoni cathepsin D (A01 family) 0.0022 0.0014 0.0007
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0022 0.0015 0.0016
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0054 0.0169 0.0169
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.004 0.01 0.0679
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0076 0.0276 0.0276
Echinococcus multilocularis cyclin dependent kinase 1 0.0049 0.0146 0.0191
Treponema pallidum phosphoglycerate kinase 0.0166 0.0705 0.3863
Trypanosoma brucei cdc2-related kinase 3 0.0049 0.0146 0.0412
Entamoeba histolytica recQ family helicase, putative 0.007 0.0246 0.0915
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0064 0.0218 0.1001
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0061 0.0201 0.1476
Mycobacterium ulcerans glutaminase 0.0267 0.1187 0.9265
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.057 0.2157
Schistosoma mansoni zinc finger protein 0.0021 0.0009 0.0001
Schistosoma mansoni vav2 0.0034 0.0073 0.0085
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0035 0.0076 0.0076
Schistosoma mansoni tyrosine kinase 0.0031 0.006 0.0068
Toxoplasma gondii exonuclease III APE 0.0042 0.0112 0.0484
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.001 0.0002
Loa Loa (eye worm) TK/EPH protein kinase 0.0083 0.0308 0.0308
Mycobacterium leprae Conserved hypothetical protein 0.0065 0.0221 0.2249
Loa Loa (eye worm) hypothetical protein 0.0061 0.0201 0.0201
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0712 0.3317 0.4397
Schistosoma mansoni importin beta-1 0.0028 0.0045 0.0048
Schistosoma mansoni tyrosine kinase 0.0042 0.0111 0.0136
Brugia malayi Immunoglobulin I-set domain containing protein 0.0346 0.1567 0.4715
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.004 0.01 0.0425
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0146 0.0609 0.0609
Brugia malayi intermediate filament protein 0.0026 0.0036 0.0095
Giardia lamblia Kinase, CMGC CK2 0.0138 0.057 0.3124
Schistosoma mansoni protein kinase 0.0023 0.002 0.0015
Trypanosoma brucei DNA topoisomerase ii 0.0251 0.1112 0.3334
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0346 0.1567 0.1567
Loa Loa (eye worm) hypothetical protein 0.0448 0.2053 0.2053
Trypanosoma brucei phosphotransferase, putative 0.0065 0.0222 0.0643
Echinococcus multilocularis cyclins 0.0048 0.0138 0.0181
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0015 0.0016
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0203 0.0882 0.6857
Echinococcus granulosus roundabout 2 0.0041 0.0106 0.0137
Trypanosoma brucei unspecified product 0.0036 0.0081 0.0217
Echinococcus multilocularis tumor protein p63 0.033 0.1488 0.2025
Echinococcus multilocularis thioredoxin glutathione reductase 0.0217 0.0948 0.1287
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0213 0.1566
Loa Loa (eye worm) hypothetical protein 0.0042 0.011 0.011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0022 0.0018 0.0025
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0186 0.0673
Echinococcus multilocularis carbonic anhydrase II 0.0712 0.3317 0.4524
Echinococcus multilocularis mitogen activated protein kinase 0.0076 0.0273 0.0365
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.016 0.016
Plasmodium falciparum ferrodoxin reductase-like protein 0.0022 0.0015 0.0004
Echinococcus multilocularis insulin receptor 0.036 0.1634 0.2225
Schistosoma mansoni jumonji domain containing protein 0.0206 0.0896 0.118
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0066 0.0185
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0015 0.0016
Trypanosoma cruzi cdc2-related kinase 1 0.0049 0.0146 0.0412
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Echinococcus granulosus Polycystic kidney disease protein 0.0038 0.0094 0.0121
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0193 0.0835 0.2497
Echinococcus granulosus carbonic anhydrase 0.0448 0.2053 0.2797
Schistosoma mansoni lipoxygenase 0.0169 0.0719 0.0944
Onchocerca volvulus 0.0232 0.1022 0.366
Plasmodium vivax aspartyl protease, putative 0.0022 0.0014 0.0077
Leishmania major protein kinase, putative 0.013 0.0531 0.1577
Plasmodium vivax importin-beta 2, putative 0.0028 0.0045 0.0322
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0144 0.0408
Schistosoma mansoni autophagin-1 (C54 family) 0.0058 0.0186 0.0235
Mycobacterium ulcerans phosphoglycerate kinase 0.0166 0.0705 0.5458
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0014
Loa Loa (eye worm) AUR protein kinase 0.013 0.0531 0.0531
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0054 0.0169 0.0481
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0054 0.017 0.0224
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0045
Loa Loa (eye worm) glutaminase 0.0267 0.1187 0.1187
Trichomonas vaginalis apoptosis inducing factor, putative 0.0022 0.0015 0.0016
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0035 0.0076 0.0096
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0448 0.2053 0.2053
Toxoplasma gondii aldo-keto reductase 0.0026 0.0037 0.0114
Brugia malayi Pre-SET motif family protein 0.003 0.0055 0.0152
Echinococcus multilocularis dnaJ subfamily B 0.0365 0.1658 0.2257
Plasmodium vivax JmjC domain containing protein 0.0044 0.0123 0.0932
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0037 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0014 0.0007
Echinococcus granulosus lysine specific demethylase 5A 0.0172 0.0734 0.0995
Schistosoma mansoni GST class-mu 0.0062 0.0209 0.0266
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0151 0.0632 0.3035
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.0213 0.0271
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.1802 0.6873
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0022 0.0014 0.0014
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Echinococcus multilocularis tyrosine protein kinase shark 0.0238 0.1051 0.1429
Brugia malayi Glycosyl hydrolases family 31 protein 0.0049 0.0144 0.0421
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0091 0.0347 0.1034
Schistosoma mansoni phd/f-box containing protein 0.0044 0.0123 0.0152
Echinococcus multilocularis cyclin B 0.009 0.0341 0.0458
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0019 0.0042
Loa Loa (eye worm) hypothetical protein 0.0166 0.0705 0.0705
Plasmodium falciparum phd finger protein, putative 0.0028 0.0046 0.016
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0147 0.0614 0.3353
Echinococcus granulosus lysine specific demethylase 6a 0.0044 0.0123 0.016
Schistosoma mansoni DNA topoisomerase II 0.0192 0.0829 0.109
Echinococcus multilocularis lamin dm0 0.0026 0.0036 0.0042
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0112 0.0774
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0348 0.1295
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.005 0.015 0.0197
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.0213 0.0627
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.004 0.01 0.0503
Trypanosoma cruzi cyclin, putative 0.009 0.0341 0.1003
Schistosoma mansoni potassium channel beta 0.0026 0.0037 0.0037
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0147 0.0614 0.1828
Leishmania major hypothetical protein, conserved 0.0022 0.0015 0.0016
Onchocerca volvulus 0.0026 0.0036 0.0099
Treponema pallidum licC protein (licC) 0.0039 0.0098 0.0465
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0061 0.0201 0.058
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0027 0.004 0.0113
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0448 0.2053 0.6182
Schistosoma mansoni protein kinase C mu 0.0076 0.0276 0.0355
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Echinococcus multilocularis phd:f box containing protein 0.0044 0.0123 0.016
Plasmodium falciparum cyclin 0.0048 0.0138 0.061
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1593 0.7532 1
Echinococcus granulosus protein kinase c iota type 0.0049 0.0144 0.0188
Echinococcus multilocularis expressed protein 0.0033 0.0066 0.0083
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0124 0.0504 0.0681
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0064 0.0218 0.1001
Onchocerca volvulus 0.0038 0.0094 0.0309
Echinococcus granulosus tyrosine protein kinase Lyn 0.0106 0.042 0.0566
Plasmodium falciparum casein kinase II beta chain 0.0071 0.0252 0.1171
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0023 0.0021 0.0021
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0112 0.0312
Entamoeba histolytica aldose reductase, putative 0.0091 0.0347 0.1304
Schistosoma mansoni glutathione-S-transferase 0.0062 0.0209 0.0266
Echinococcus multilocularis aurora kinase A 0.013 0.0531 0.0718
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0032 0.0068
Echinococcus granulosus dna polymerase eta 0.0077 0.0277 0.0371
Loa Loa (eye worm) glutaminase 2 0.0267 0.1187 0.1187
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0015 0.0016
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0022 0.0015 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0348 0.1295
Entamoeba histolytica cell division protein kinase 2, putative 0.0049 0.0146 0.0531
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0084 0.0311 0.0418
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0015 0.0016
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0166 0.0705 0.339
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0038 0.01
Echinococcus granulosus c src tyrosine kinase 0.0042 0.0111 0.0144
Trichomonas vaginalis sucrase-isomaltase, putative 0.0049 0.0144 0.0514
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.005 0.015 0.0197
Plasmodium falciparum importin beta, putative 0.0028 0.0045 0.0153
Brugia malayi Casein kinase II, alpha chain 0.0138 0.057 0.1706
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.017 0.1227
Schistosoma mansoni methyl-cpg binding protein mbd 0.0023 0.0021 0.0016
Echinococcus multilocularis muscleblind protein 0.0056 0.018 0.0238
Schistosoma mansoni prion interactor pint1 0.0029 0.005 0.0055
Schistosoma mansoni hypothetical protein 0.0031 0.006 0.0068
Schistosoma mansoni tyrosine kinase 0.0042 0.0111 0.0136
Echinococcus multilocularis snurportin 1 0.03 0.1348 0.1833
Echinococcus granulosus snurportin 1 0.03 0.1348 0.1833
Trichomonas vaginalis cyclins, putative 0.009 0.0341 0.1269
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0054 0.017 0.0485
Echinococcus granulosus tyrosine protein kinase Src64B 0.0099 0.0384 0.0516
Brugia malayi aspartic protease BmAsp-2, identical 0.0022 0.0014 0.0027
Trypanosoma brucei protein kinase, putative 0.0076 0.0273 0.0798
Echinococcus granulosus glutathione S transferase 0.0045 0.0124 0.0161
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0022 0.0014 0.0007
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0041 0.0106 0.0453
Brugia malayi Muscleblind-like protein 0.0056 0.018 0.0528
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0076 0.0273 0.0798
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0112 0.0484
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0124 0.0504 0.0681
Loa Loa (eye worm) aspartyl protease 6 0.0022 0.0014 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.1802 0.6873
Entamoeba histolytica protein kinase domain containing protein 0.0054 0.0169 0.0619
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Brugia malayi Cyclin, N-terminal domain containing protein 0.009 0.0341 0.1015
Entamoeba histolytica protein kinase domain containing protein 0.0054 0.0169 0.0619
Trypanosoma brucei unspecified product 0.0036 0.0081 0.0217
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0032 0.0061 0.0449
Echinococcus granulosus cyclin dependent kinase 1 0.0049 0.0146 0.0191
Trichomonas vaginalis cyclin A, putative 0.009 0.0341 0.1269
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0236 0.0865
Echinococcus granulosus chromobox protein 1 0.0068 0.0236 0.0314
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0032 0.0068
Echinococcus multilocularis 6 phosphofructokinase 0.0147 0.0614 0.0831
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0191 0.0191
Echinococcus multilocularis ubiquitin specific protease 41 0.005 0.015 0.0197
Brugia malayi Hr1 repeat family protein 0.0035 0.0076 0.0214
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Echinococcus granulosus NCK adaptor protein 0.0027 0.0038 0.0044
Onchocerca volvulus ERI1 exoribonuclease 3 homolog 0.0029 0.005 0.015
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.004 0.01 0.0425
Leishmania major DNA polymerase kappa, putative 0.0058 0.0189 0.0543
Loa Loa (eye worm) programmed cell death 8 0.0022 0.0015 0.0015
Brugia malayi Sex muscle abnormal protein 5 0.0027 0.0038 0.01
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0124 0.0504 0.0681
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0023 0.0019 0.0018
Brugia malayi Pepsin A precursor 0.0022 0.0014 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0504 0.0658
Entamoeba histolytica cyclin family protein 0.0048 0.0138 0.0502
Entamoeba histolytica phosphofructokinase, putative 0.0147 0.0614 0.2325
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0071 0.0252 0.0735
Entamoeba histolytica PH domain containing protein kinase, putative 0.0064 0.0218 0.081
Entamoeba histolytica protein kinase, putative 0.0091 0.0348 0.1305
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.017 0.1227
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0201 0.058
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0019 0.0018
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0148 0.062 0.0839
Echinococcus multilocularis peregrin 0.0032 0.0062 0.0077
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0063 0.0161
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0022 0.0015 0.0012
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0064 0.0218 0.0643
Loa Loa (eye worm) oxidoreductase 0.0091 0.0347 0.0347
Trypanosoma cruzi aldo/keto reductase, putative 0.0091 0.0347 0.1022
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0053 0.0164 0.0216
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0076
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0022 0.0015 0.0012
Echinococcus multilocularis jumonji domain containing 1A 0.0044 0.0123 0.016
Plasmodium falciparum glutathione reductase 0.0061 0.0201 0.092
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0023 0.002 0.0032
Loa Loa (eye worm) cyclin domain-containing protein 0.0048 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0055 0.0172 0.0172
Mycobacterium tuberculosis Probable dehydrogenase 0.0053 0.0164 0.118
Leishmania major mitochondrial DNA topoisomerase II 0.0251 0.1112 0.3334
Plasmodium falciparum flap endonuclease 1 0.0025 0.0032 0.0089
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.005 0.015 0.0424
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0069 0.0241 0.1787
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.0282 0.2116
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.057 0.2147
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.017 0.0214
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0019 0.0042
Leishmania major hypothetical protein, conserved 0.0022 0.0015 0.0016
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0022 0.0044
Leishmania major hypothetical protein, conserved 0.0044 0.0123 0.0343
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0022 0.0015 0.0016
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0148 0.062 0.0812
Echinococcus granulosus flap endonuclease 1 0.0025 0.0032 0.0036
Schistosoma mansoni microtubule-associated protein tau 0.155 0.7325 0.9725
Schistosoma mansoni hypothetical protein 0.0038 0.0094 0.0114
Loa Loa (eye worm) hypothetical protein 0.0076 0.0272 0.0272
Echinococcus multilocularis lamin 0.0026 0.0036 0.0042
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0067 0.0175
Giardia lamblia Aldose reductase 0.0091 0.0347 0.1882
Echinococcus multilocularis dna polymerase eta 0.0077 0.0277 0.0371
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.005 0.015 0.0187
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0079
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.015 0.0437
Schistosoma mansoni hypothetical protein 0.0031 0.006 0.0068
Schistosoma mansoni tyrosine kinase 0.0099 0.0384 0.0498
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0045 0.0153
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0213 0.1566
Brugia malayi protein kinase C II. 0.0049 0.0144 0.0419
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0049 0.0144 0.0144
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0705 0.0925
Echinococcus granulosus carbonic anhydrase II 0.0712 0.3317 0.4524
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0022 0.0018 0.0019
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Mycobacterium tuberculosis Probable oxidoreductase 0.0091 0.0347 0.2632
Echinococcus multilocularis lysosomal alpha glucosidase 0.022 0.0965 0.131
Giardia lamblia Kinase, CMGC GSK 0.0054 0.0169 0.0884
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0019 0.0035
Toxoplasma gondii CMGC kinase, CK2 family 0.0138 0.057 0.2728
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0409 0.1865 0.561
Brugia malayi phosphofructokinase 0.0147 0.0614 0.1839
Echinococcus granulosus glutathione s transferase mu 0.0062 0.0209 0.0278
Brugia malayi hypothetical protein 0.0035 0.0078 0.0222
Echinococcus multilocularis nervana 2 0.0053 0.0164 0.0216
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0122 0.0496 0.5249
Brugia malayi Protein kinase domain containing protein 0.0091 0.0348 0.1035
Echinococcus granulosus tyrosine protein kinase HCK 0.0072 0.0256 0.0342
Schistosoma mansoni nck2/grb4 0.0027 0.0038 0.0039
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.0015 0.0029
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0063 0.0213
Toxoplasma gondii aldehyde dehydrogenase 0.0054 0.017 0.0765
Schistosoma mansoni tyrosine kinase 0.0033 0.0066 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0273 0.0351
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0054 0.0169 0.0212
Entamoeba histolytica hypothetical protein 0.0035 0.0078 0.0273
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0366 0.166 0.2261
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.013 0.0531 0.0718
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0031 0.006 0.0074
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0052 0.0158 0.0158
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0023 0.002 0.0019
Brugia malayi glutathione transferase 0.0023 0.0021 0.005
Toxoplasma gondii 6-phosphofructokinase 0.004 0.01 0.0425
Loa Loa (eye worm) raf kinase 0.0217 0.0949 0.0949
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0092 0.0351 0.3663
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0061 0.0201 0.092
Trichomonas vaginalis DNA helicase recq, putative 0.007 0.0246 0.0903
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0166 0.0209
Echinococcus granulosus lamin 0.0026 0.0036 0.0042
Entamoeba histolytica cell division protein kinase 2, putative 0.0049 0.0146 0.0531
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0023 0.0018 0.0021
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0148 0.062 0.1845
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0019 0.0019
Echinococcus multilocularis rac serine:threonine kinase 0.0064 0.0218 0.0291
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Brugia malayi Thioredoxin reductase 0.0216 0.0942 0.2828
Entamoeba histolytica protein kinase 2, putative 0.0061 0.02 0.0739
Schistosoma mansoni hypothetical protein 0.0165 0.0701 0.0921
Echinococcus multilocularis cyclins 0.0048 0.0138 0.0181
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0022 0.0014 0.0007
Schistosoma mansoni rab6-interacting 0.0038 0.0094 0.0114
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0241 0.0699
Giardia lamblia Sgs1 DNA helicase, putative 0.0064 0.0218 0.1159
Plasmodium falciparum carbonic anhydrase 0.0448 0.2053 1
Onchocerca volvulus 0.0055 0.0172 0.0591
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.1802 0.6873
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0091 0.0347 0.1022
Onchocerca volvulus 0.0031 0.006 0.0185
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0015 0.0016
Schistosoma mansoni bromodomain containing protein 0.0089 0.0335 0.0433
Trypanosoma brucei rac serine-threonine kinase, putative 0.0091 0.0348 0.1023
Echinococcus multilocularis zinc finger protein 0.003 0.0052 0.0063
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0049 0.0143 0.0187
Schistosoma mansoni tyrosine kinase 0.0223 0.0975 0.1285
Echinococcus multilocularis musashi 0.0026 0.0036 0.0042
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0042 0.0111 0.0144
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0067 0.0175
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0071 0.0252 0.1171
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.005 0.015 0.0424
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.004 0.01 0.0358
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0088 0.0332 0.0446
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Brugia malayi Glycosyl hydrolases family 31 protein 0.022 0.0965 0.2898
Plasmodium falciparum thioredoxin reductase 0.0061 0.0201 0.092
Toxoplasma gondii aldose reductase, putative 0.0091 0.0347 0.1637
Trypanosoma brucei RNA helicase, putative 0.0202 0.0877 0.2623
Toxoplasma gondii RNA 2'-phosphotransferase, Tpt1/KptA family protein 0.0065 0.0222 0.1021
Brugia malayi glutathione reductase 0.0216 0.0942 0.2828
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0039 0.0097 0.0278
Schistosoma mansoni lamin 0.0026 0.0036 0.0036
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0124 0.0504 0.0681
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0046 0.0056
Brugia malayi NADH-dependent xylose reductase 0.0026 0.0037 0.0097
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0273 0.1009
Leishmania major NADH dehydrogenase, putative 0.0022 0.0015 0.0016
Entamoeba histolytica recQ family DNA helicase 0.0033 0.0067 0.023
Brugia malayi ephrin receptor 1 precursor 0.004 0.0104 0.0299
Schistosoma mansoni cell adhesion molecule 0.0023 0.0019 0.0013
Entamoeba histolytica protein kinase domain containing protein 0.013 0.0531 0.2007
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0031 0.006 0.0074
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0066 0.0066
Onchocerca volvulus 0.003 0.0053 0.0161
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0035 0.0076 0.0096
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0058 0.0186 0.0235
Onchocerca volvulus 0.0091 0.0347 0.1224
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.013 0.0531 0.2007
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0712 0.3317 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0201 0.058
Echinococcus granulosus lipoxygenase domain containing protein 0.0038 0.0094 0.0121
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0053 0.0164 0.1627
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0124 0.0504 0.1496
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0705 0.2103
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0022 0.0018 0.0025
Giardia lamblia Aurora kinase 0.013 0.0531 0.2906
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0088 0.0329 0.0329
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0078 0.0099
Echinococcus granulosus tyrosine protein kinase ABL1 0.0031 0.006 0.0074
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0044 0.0044
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0166 0.0219
Schistosoma mansoni sulfide quinone reductase 0.0022 0.0015 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0123 0.0123
Trichomonas vaginalis cyclins, putative 0.009 0.0341 0.1269
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0053 0.0164 0.118
Brugia malayi Variant SH3 domain containing protein 0.003 0.0054 0.0149
Trichomonas vaginalis cyclins, putative 0.0048 0.0138 0.0491
Echinococcus multilocularis voltage gated potassium channel subunit 0.0026 0.0037 0.0043
Brugia malayi casein kinase II, putaitve 0.0021 0.001 0.0016
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0026 0.0037 0.0043
Brugia malayi polk-prov protein 0.0042 0.0111 0.0322
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0022 0.0014 0.0014
Leishmania major trypanothione reductase 0.0216 0.0942 0.2819
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0273 0.1009
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0044 0.0123 0.0343
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0201 0.058
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0062 0.0208 0.0208
Echinococcus granulosus Exonuclease RNase T DNA polymerase III 0.0029 0.005 0.0061
Giardia lamblia Kinase, CMGC MAPK 0.0076 0.0273 0.1467
Plasmodium vivax casein kinase II beta chain, putative 0.0071 0.0252 0.1948
Plasmodium vivax unspecified product 0.0138 0.057 0.4437
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0236 0.0236
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0076 0.0273 0.0798
Loa Loa (eye worm) SRC-1 0.0099 0.0384 0.0384
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0112 0.0146
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0186 0.0673
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0026 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0019 0.0042
Trichomonas vaginalis cyclin D, putative 0.0048 0.0138 0.0491
Schistosoma mansoni neuroglian 0.0023 0.0019 0.0013
Onchocerca volvulus 0.0031 0.006 0.0185
Plasmodium vivax DNA gyrase subunit A, putative 0.0286 0.128 1
Trichomonas vaginalis DNA topoisomerase II, putative 0.0192 0.0829 0.314
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0099 0.0384 0.0516
Brugia malayi Bromodomain containing protein 0.0105 0.041 0.1224
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.015 0.0535
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0078 0.0099
Echinococcus multilocularis tyrosine protein kinase HCK 0.0072 0.0256 0.0342
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0202 0.0583
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0214 0.0932 0.7252
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.0282 0.0825
Trypanosoma cruzi polo-like protein kinase, putative 0.0146 0.0609 0.1812
Echinococcus granulosus cyclin B 0.009 0.0341 0.0458
Schistosoma mansoni rab6-interacting 0.0038 0.0094 0.0114
Trypanosoma cruzi cdc2-related kinase 3 0.0049 0.0146 0.0412
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0448 0.2053 0.6182
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0112 0.0548
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0201 0.058
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0112 0.0312
Echinococcus granulosus tyrosine protein kinase Fyn 0.0099 0.0384 0.0516
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.007 0.0246 0.0715
Echinococcus multilocularis Exonuclease, RNase T DNA polymerase III 0.0029 0.005 0.0061
Echinococcus granulosus fetal alzheimer antigen falz 0.0034 0.0071 0.0089
Loa Loa (eye worm) hypothetical protein 0.009 0.0341 0.0341
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0022 0.0044
Chlamydia trachomatis DNA gyrase subunit B 0.0203 0.0882 0.6857
Plasmodium vivax serine/threonine protein kinase 6, putative 0.013 0.0531 0.4131
Leishmania major ATP-dependent phosphofructokinase 0.0147 0.0614 0.1828
Schistosoma mansoni alpha glucosidase 0.0049 0.0144 0.018
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0099 0.0384 0.0516
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.057 0.2147
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0022 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0084 0.0312 0.0312
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0076 0.0251
Onchocerca volvulus Serine\/threonine kinase homolog 0.0146 0.0609 0.2167
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0022 0.0044
Loa Loa (eye worm) plexin A 0.002 0.0006 0.0006
Echinococcus multilocularis cyclin b3 0.0048 0.0138 0.0181
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0015 0.0016
Echinococcus granulosus importin subunit beta 1 0.0028 0.0045 0.0054
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.003 0.0054 0.0066
Loa Loa (eye worm) hypothetical protein 0.0076 0.0272 0.0272
Schistosoma mansoni blooms syndrome DNA helicase 0.0033 0.0067 0.0078
Echinococcus granulosus titin 0.0021 0.0009 0.0004
Schistosoma mansoni hypothetical protein 0.0035 0.0078 0.0092
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0061 0.02 0.1537
Schistosoma mansoni blooms syndrome DNA helicase 0.006 0.0196 0.0249
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0061 0.0201 0.1476
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0053 0.0164 0.0216
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0054 0.017 0.0224
Plasmodium falciparum cysteine protease ATG4, putative 0.0022 0.0018 0.0019
Echinococcus multilocularis protein kinase shaggy 0.0054 0.0169 0.0222
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0124 0.0504 0.1496
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0022 0.0014 0.0007
Echinococcus multilocularis JmjC domain containing protein 4 0.0044 0.0123 0.016
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0148 0.0617 0.2197
Plasmodium falciparum LCCL domain-containing protein 0.0038 0.0094 0.0396
Entamoeba histolytica thioredoxin reductase, putative 0.0022 0.0015 0.0029
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0098 0.0657
Schistosoma mansoni serine/threonine-protein kinase 0.0064 0.0218 0.0279
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0192 0.0829 0.1124
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0166 0.0705 0.7525
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.057 0.2147
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0099 0.0384 0.0516
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0063 0.0161
Echinococcus granulosus aldo keto reductase 0.0091 0.0347 0.0467
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0099 0.0384 0.0516
Brugia malayi RNA, U transporter 1 0.008 0.0293 0.087
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0037 0.0102
Toxoplasma gondii selenide, water dikinase 0.0022 0.0015 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0014 0.0007
Trichomonas vaginalis 6-phosphofructokinase, putative 0.004 0.01 0.0346
Loa Loa (eye worm) TK/INSR protein kinase 0.036 0.1634 0.1634
Onchocerca volvulus 0.0048 0.0141 0.0478
Trypanosoma brucei squalene monooxygenase, putative 0.0244 0.1076 0.3224
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0022 0.0015 0.0016
Schistosoma mansoni carbonic anhydrase-related 0.0448 0.2053 0.2717
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.005 0.015 0.0778
Echinococcus granulosus aldo keto reductase 0.0091 0.0347 0.0467
Entamoeba histolytica PH domain containing protein kinase, putative 0.0064 0.0218 0.081
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0061 0.0201 0.092
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0044 0.0123 0.0343
Schistosoma mansoni tyrosine kinase 0.0261 0.1159 0.1529
Brugia malayi Phosphoglycerate kinase 0.0166 0.0705 0.2114
Trichomonas vaginalis conserved hypothetical protein 0.005 0.015 0.0535
Schistosoma mansoni tyrosine kinase 0.0284 0.1271 0.1677
Echinococcus multilocularis tyrosine kinase 0.0031 0.006 0.0074
Echinococcus granulosus tyrosine protein kinase Blk 0.0088 0.0332 0.0446
Loa Loa (eye worm) AGC/PKA protein kinase 0.0124 0.0504 0.0504
Entamoeba histolytica serine/threonine protein kinase, putative 0.0146 0.0609 0.2305
Brugia malayi Bromodomain containing protein 0.0052 0.0158 0.0463
Echinococcus granulosus tumor protein p63 0.033 0.1488 0.2025
Toxoplasma gondii phosphofructokinase domain-containing protein 0.004 0.01 0.0425
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0022 0.0014 0.0007
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0023 0.002 0.0019
Echinococcus multilocularis geminin 0.0165 0.0701 0.0951
Onchocerca volvulus 0.0031 0.006 0.0185
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.057 0.2147
Schistosoma mansoni pol-related 0.0091 0.0347 0.045
Leishmania major cyclin 0.009 0.0341 0.1003
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0286 0.128 0.7078
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0203 0.0882 0.4853
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0092 0.0351 0.2656
Trichomonas vaginalis aldo/keto reductase, putative 0.0091 0.0347 0.1294
Schistosoma mansoni alpha-glucosidase 0.019 0.0818 0.1076
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0026 0.0023
Echinococcus multilocularis glutathione s transferase mu 0.0062 0.0209 0.0278
Onchocerca volvulus 0.0053 0.0165 0.0565
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0063 0.024
Trypanosoma cruzi NADH dehydrogenase, putative 0.0022 0.0015 0.0016
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0022 0.0015 0.0016
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0035 0.0076 0.0096
Giardia lamblia Kinase, CMGC CDK 0.0049 0.0146 0.0756
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0046 0.005
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0124 0.0504 0.0681
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0046 0.0334
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0044 0.0123 0.0152
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.057 0.2147
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0071 0.0252 0.0735
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.0015 0.0012
Schistosoma mansoni sulfide quinone reductase 0.0022 0.0015 0.0008
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0052 0.0158 0.0198
Toxoplasma gondii phosphofructokinase PFKII 0.004 0.01 0.0425
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0031 0.006 0.0074
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0124 0.0504 0.1496
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0091 0.0347 0.1034
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0061 0.0201 0.1547
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.002 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0348 0.1295
Plasmodium vivax glutathione S-transferase, putative 0.0023 0.0021 0.0136
Echinococcus granulosus activin receptor type 0.0023 0.002 0.0019
Echinococcus multilocularis serine:threonine protein kinase 38 0.0035 0.0076 0.0096
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Plasmodium vivax DNA gyrase subunit B, putative 0.0203 0.0882 0.6883
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0057 0.0185 0.0532
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0026 0.0037 0.0102
Loa Loa (eye worm) hypothetical protein 0.0026 0.0034 0.0034
Echinococcus multilocularis neutral alpha glucosidase AB 0.0049 0.0144 0.0189
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0091 0.0347 0.0467
Chlamydia trachomatis DNA gyrase subunit A 0.0056 0.0178 0.1294
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0044 0.0123 0.0343
Entamoeba histolytica phosphoglycerate kinase, putative 0.0166 0.0705 0.2674
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0032 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0064 0.0218 0.0632
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0366 0.166 0.2261
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.022 0.0965 0.0965
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0091 0.0347 0.0467
Onchocerca volvulus 0.0026 0.0036 0.0099
Toxoplasma gondii RNA 2'-phosphotransferase, Tpt1/KptA family protein 0.0065 0.0222 0.1021
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0286 0.128 1
Trypanosoma cruzi aurora B kinase, putative 0.013 0.0531 0.1577
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0705 0.2665
Echinococcus granulosus geminin 0.0165 0.0701 0.0951
Loa Loa (eye worm) jmjC domain-containing protein 0.0172 0.0734 0.0734
Echinococcus granulosus Protein kinase C brain isozyme 0.0049 0.0144 0.0188
Echinococcus multilocularis RUN 0.0038 0.0094 0.0121
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0049 0.0143 0.0187
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0015 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0201 0.1476
Entamoeba histolytica PH domain containing protein kinase, putative 0.0128 0.0522 0.1975
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0091 0.0347 0.0467
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.0888 0.0888
Brugia malayi Protein kinase domain containing protein 0.0031 0.006 0.0166
Giardia lamblia Aldose reductase 0.0091 0.0347 0.1882
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0023 0.0021 0.0017
Echinococcus granulosus mitogen activated protein kinase 0.0076 0.0273 0.0365
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0112 0.0774
Echinococcus granulosus casein kinase ii subunit alpha 0.0138 0.057 0.0771
Schistosoma mansoni tyrosine kinase 0.0269 0.1197 0.158
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0049 0.0146 0.0146
Onchocerca volvulus 0.0303 0.136 0.4882
Toxoplasma gondii aurora kinase 0.013 0.0531 0.2537
Echinococcus granulosus expressed protein 0.0033 0.0066 0.0083
Echinococcus granulosus chromobox protein 1 0.0068 0.0236 0.0314
Loa Loa (eye worm) hypothetical protein 0.0448 0.2053 0.2053
Giardia lamblia NADH oxidase lateral transfer candidate 0.0061 0.0201 0.1066
Brugia malayi jmjC domain containing protein 0.0044 0.0123 0.0356
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0005
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0071 0.0252 0.0735
Trypanosoma brucei prostaglandin f synthase 0.0091 0.0347 0.1022
Brugia malayi CXXC zinc finger family protein 0.0054 0.0167 0.049
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0022 0.0015 0.0004
Brugia malayi hypothetical protein 0.0038 0.0094 0.027
Loa Loa (eye worm) hypothetical protein 0.005 0.015 0.015
Brugia malayi jmjC domain containing protein 0.0225 0.0988 0.2968
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0022 0.0014 0.0011
Echinococcus multilocularis ephrin type A receptor 4 A 0.0081 0.0299 0.0401
Plasmodium vivax thioredoxin reductase, putative 0.0216 0.0942 0.735
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0166 0.0705 0.5458
Schistosoma mansoni tyrosine kinase 0.0419 0.1915 0.2534
Brugia malayi hypothetical protein 0.0031 0.006 0.0166
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0185 0.0532
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0251 0.1112 0.3334
Plasmodium vivax 6-phosphofructokinase, putative 0.004 0.01 0.0756
Echinococcus granulosus NDR protein kinase 0.0035 0.0076 0.0096
Schistosoma mansoni protein phosphatase 2C 0.0044 0.0123 0.0152
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0468 0.0468
Echinococcus multilocularis chromobox protein 1 0.0068 0.0236 0.0314
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.004 0.01 0.048
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0022 0.0015 0.0012
Schistosoma mansoni DNA helicase recq5 0.0064 0.0218 0.0278
Echinococcus granulosus raf serine:threonine protein kinase 0.0233 0.1023 0.139
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0148 0.0617 0.2197
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0037 0.0102
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0148 0.062 0.1856
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0036 0.0036
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0225 0.0988 0.1342
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0348 0.1295
Chlamydia trachomatis phosphoglycerate kinase 0.0166 0.0705 0.5458
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0022 0.0014 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0022 0.0014 0.0007
Plasmodium vivax SET domain protein, putative 0.003 0.0055 0.0403
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Schistosoma mansoni ephrin receptor 0.0021 0.001 0.0002
Toxoplasma gondii hypothetical protein 0.0066 0.0226 0.1039
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0099 0.0384 0.0516
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0712 0.3317 1
Trypanosoma brucei NADH dehydrogenase 0.0022 0.0015 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.004 0.01 0.0346
Trichomonas vaginalis phosphofructokinase, putative 0.004 0.01 0.0346
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.1802 0.6873
Giardia lamblia Hypothetical protein 0.0048 0.0138 0.0714
Brugia malayi protein unc-22 0.0021 0.0009 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0504 0.0658
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0091 0.0347 0.0467
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0116 0.0466 0.0629
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0091 0.0347 0.0467
Echinococcus granulosus cyclin B3 1 0.0048 0.0138 0.0181
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0063 0.0161
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0044 0.0123 0.0535
Echinococcus multilocularis glutathione S transferase 0.0062 0.0209 0.0278
Echinococcus granulosus hypothetical protein 0.0091 0.0347 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0144 0.0179
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0111 0.0309
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0202 0.0583
Echinococcus granulosus lipoxygenase domain containing protein 0.0038 0.0094 0.0121
Echinococcus granulosus L aminoadipate semialdehyde 0.0031 0.006 0.0074
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0091 0.0347 0.0467
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0022 0.0044
Onchocerca volvulus 0.0091 0.0347 0.1224
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0099 0.0384 0.0516
Echinococcus granulosus nervana 2 0.0053 0.0164 0.0216
Trichomonas vaginalis DNA polymerase eta, putative 0.0078 0.0282 0.1044
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0116 0.0466 0.0629
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0213 0.0283
Entamoeba histolytica casein kinase, putative 0.0138 0.057 0.2157
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0705 0.2103
Plasmodium falciparum serine/threonine protein kinase, putative 0.013 0.0531 0.2537
Schistosoma mansoni jumonji domain containing protein 0.0044 0.0123 0.0152
Echinococcus granulosus lamin dm0 0.0026 0.0036 0.0042
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0146 0.0609 0.0824
Echinococcus granulosus cyclin dependent kinase 5 0.0049 0.0146 0.0191
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0166 0.0705 0.339
Schistosoma mansoni adapter molecule crk 0.0027 0.0038 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0147 0.0614 0.2315
Echinococcus granulosus epidermal growth factor receptor 0.0419 0.1915 0.2609
Loa Loa (eye worm) hypothetical protein 0.0031 0.006 0.006
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0061 0.0201 0.0267
Entamoeba histolytica peptidase, C54 family 0.0022 0.0018 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.1802 0.6873
Trypanosoma cruzi cdc2-related kinase 1 0.0049 0.0146 0.0412
Echinococcus granulosus microtubule associated protein 2 0.155 0.7325 1
Trypanosoma cruzi DNA topoisomerase II, putative 0.0176 0.0751 0.2243
Schistosoma mansoni hypothetical protein 0.0448 0.2053 0.2717
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0409 0.1865 0.561
Brugia malayi Probable DNA topoisomerase II 0.0192 0.0829 0.2487
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0015 0.0016
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0124 0.0504 0.1496
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0064 0.0218 0.0218
Echinococcus multilocularis cyclins 0.0048 0.0138 0.0181
Schistosoma mansoni zinc finger protein 0.003 0.0052 0.0057
Trypanosoma brucei DNA polymerase eta, putative 0.0077 0.0277 0.0809
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.007 0.0245 0.0713
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0054 0.0169 0.0759
Schistosoma mansoni tyrosine kinase 0.0284 0.1271 0.1677
Trypanosoma brucei Casein kinase II 0.0138 0.057 0.1695
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0201 0.058
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0091 0.0347 0.1294
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0014
Trichomonas vaginalis cyclin B, putative 0.0048 0.0138 0.0491
Trypanosoma brucei cdc2-related kinase 1 0.0049 0.0146 0.0412
Echinococcus multilocularis glutamate synthase 0.0022 0.0015 0.0012
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0091 0.0347 0.1294
Entamoeba histolytica protein kinase, putative 0.0088 0.0329 0.1235
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0022 0.0015 0.0016
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0061 0.0201 0.1547
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0395 0.1802 0.6873
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0031 0.006 0.0074
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0241 0.0699
Echinococcus multilocularis glutathione S transferase 0.0023 0.0021 0.0021
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0214 0.0932 0.7252
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Trypanosoma cruzi polo-like protein kinase, putative 0.0146 0.0609 0.1812
Plasmodium falciparum JmjC domain-containing protein, putative 0.0044 0.0123 0.0535
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0093 0.0303
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0107 0.0369
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0061 0.02 0.0576
Echinococcus multilocularis nervana 2 0.0053 0.0164 0.0216
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.005 0.015 0.0424
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.0015 0.0012
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0022 0.0015 0.0016
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.0213 0.1566
Brugia malayi Cyclin, N-terminal domain containing protein 0.009 0.0341 0.1015
Plasmodium vivax phosphoglycerate kinase, putative 0.0166 0.0705 0.5495
Trypanosoma brucei mitotic cyclin 6 0.009 0.0341 0.1003
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0058 0.0186 0.0533
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.057 0.2147
Trichomonas vaginalis phosphofructokinase, putative 0.004 0.01 0.0346
Trypanosoma cruzi cyclin 6, putative 0.009 0.0341 0.1003
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0022 0.0015 0.0004
Leishmania major carbonic anhydrase-like protein 0.0712 0.3317 1
Echinococcus granulosus ubiquitin specific protease 41 0.005 0.015 0.0197
Leishmania major DNA polymerase eta, putative 0.0077 0.0277 0.0809
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0022 0.0018 0.0025
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.007 0.0246 0.0715
Echinococcus granulosus tyrosine kinase 0.0031 0.006 0.0074
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0022 0.0015 0.0024
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0049 0.0146 0.0647
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0448 0.2053 0.6182
Echinococcus multilocularis N chimaerin 0.003 0.0054 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0146 0.0519
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0148 0.062 0.0839
Leishmania major protein kinase A catalytic subunit isoform 1 0.0124 0.0504 0.1496
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0064 0.0218 0.029
Onchocerca volvulus 0.0022 0.0014 0.0018
Schistosoma mansoni tRNA splicing 2' phosphotransferase 1 0.0065 0.0222 0.0283
Brugia malayi Importin beta-1 subunit 0.0028 0.0045 0.0121
Toxoplasma gondii hypothetical protein 0.0036 0.0083 0.0341
Echinococcus granulosus serine/threonine protein kinase 0.0064 0.0218 0.0291
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0023 0.002 0.003
Trichomonas vaginalis cyclin D, putative 0.0048 0.0138 0.0491
Loa Loa (eye worm) hypothetical protein 0.0096 0.0368 0.0368
Trypanosoma cruzi aldo/keto reductase, putative 0.0026 0.0037 0.0083
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0071 0.0252 0.088
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0134 0.0552 0.0552
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0022 0.0015 0.0029
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Schistosoma mansoni phosphatidylserine receptor 0.0044 0.0123 0.0152
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0051 0.0138
Echinococcus granulosus jumonji domain containing protein 0.004 0.01 0.0128
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0201 0.058
Loa Loa (eye worm) AGC/NDR protein kinase 0.0035 0.0076 0.0076
Echinococcus multilocularis NCK adaptor protein 0.0027 0.0038 0.0044
Treponema pallidum NADH oxidase 0.0061 0.0201 0.1045
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0166 0.0705 0.5458
Echinococcus granulosus dna polymerase kappa 0.0078 0.0282 0.0378
Plasmodium vivax ferrodoxin reductase, putative 0.0022 0.0015 0.0083
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0112 0.0112
Schistosoma mansoni aldo-keto reductase 0.0091 0.0347 0.045
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0063 0.0161
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0094 0.0322
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0124 0.0504 0.1496
Loa Loa (eye worm) glutathione reductase 0.0216 0.0942 0.0942
Schistosoma mansoni jumonji/arid domain-containing protein 0.0172 0.0734 0.0964
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0112 0.031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0024 0.002
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0062 0.0206 0.2087
Echinococcus multilocularis inositol monophosphatase 1 0.0069 0.0241 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0039 0.0112
Onchocerca volvulus 0.0091 0.0347 0.1224
Loa Loa (eye worm) oxidoreductase 0.0091 0.0347 0.0347
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.017 0.0214
Schistosoma mansoni glutamate synthase 0.0022 0.0015 0.0008
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0022 0.0015 0.0029
Schistosoma mansoni cathepsin D (A01 family) 0.0022 0.0014 0.0007
Loa Loa (eye worm) 6-phosphofructokinase 0.0147 0.0614 0.0614
Echinococcus granulosus RUN 0.0038 0.0094 0.0121
Mycobacterium ulcerans 6-phosphofructokinase 0.0147 0.0614 0.4737
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0076 0.0273 0.0798
Onchocerca volvulus 0.0031 0.006 0.0185
Trichomonas vaginalis aldo/keto reductase, putative 0.0091 0.0347 0.1294
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Brugia malayi C1-like domain containing protein 0.0076 0.0276 0.0819
Plasmodium falciparum thioredoxin reductase 0.0216 0.0942 0.4551
Schistosoma mansoni DNA polymerase eta 0.0077 0.0277 0.0357
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0021 0.0009 0.0009
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Trichomonas vaginalis AGC family protein kinase 0.013 0.0531 0.1997
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0024
Toxoplasma gondii AGC kinase 0.0124 0.0504 0.2405
Echinococcus multilocularis cyclin dependent kinase 1 0.0049 0.0146 0.0191
Giardia lamblia Kinase, PLK 0.0146 0.0609 0.334
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0032 0.0095
Schistosoma mansoni glutaminase 0.0267 0.1187 0.1566
Leishmania major prostaglandin f synthase, putative 0.0091 0.0347 0.1022
Onchocerca volvulus 0.0031 0.006 0.0186
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.0482 0.2217 0.2217
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0203 0.0882 0.6857
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0026 0.0037 0.0037
Echinococcus granulosus Glutaredoxin protein 5 0.0054 0.017 0.0225
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0049 0.0144 0.0144
Brugia malayi Bromodomain containing protein 0.0032 0.0062 0.0172
Plasmodium falciparum casein kinase 2, alpha subunit 0.0138 0.057 0.2728
Brugia malayi Eukaryotic aspartyl protease family protein 0.0022 0.0014 0.0027
Schistosoma mansoni cyclin B3 0.0048 0.0138 0.0172
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0015 0.0004
Brugia malayi Protein kinase domain containing protein 0.0031 0.006 0.0166
Plasmodium vivax 6-phosphofructokinase, putative 0.004 0.01 0.0756
Plasmodium falciparum glutathione S-transferase 0.0062 0.0209 0.0959
Leishmania major DNA polymerase eta, putative 0.0041 0.0106 0.0293
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0088 0.0332 0.0446
Loa Loa (eye worm) apoptosis regulator protein 0.0031 0.006 0.006
Echinococcus granulosus cysteine protease atg4b 0.0058 0.0186 0.0246
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0106 0.0293
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.005 0.015 0.0197
Echinococcus multilocularis roundabout 2 0.0041 0.0106 0.0137
Loa Loa (eye worm) hypothetical protein 0.0042 0.0113 0.0113
Echinococcus granulosus tyrosine protein kinase shark 0.0238 0.1051 0.1429
Entamoeba histolytica protein kinase, putative 0.0091 0.0348 0.1305
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.015 0.0546
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0049 0.0144 0.064
Echinococcus granulosus cpg binding protein 0.0059 0.0194 0.0257
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0705 0.2103
Brugia malayi jmjC domain containing protein 0.0044 0.0123 0.0356
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0035 0.0035
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0099 0.0384 0.0516
Loa Loa (eye worm) TK protein kinase 0.0072 0.0256 0.0256
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0046 0.016
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.018
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0138 0.057 0.057
Plasmodium vivax plasmepsin V, putative 0.0022 0.0014 0.0077
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0099 0.0384 0.0516
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0064 0.0218 0.029
Brugia malayi p70 ribosomal S6 kinase beta 0.0088 0.0329 0.098
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.003 0.0055 0.0055
Loa Loa (eye worm) casein kinase II 0.0021 0.001 0.001
Leishmania major aldo-keto reductase-like protein 0.0091 0.0347 0.1022
Echinococcus granulosus growth factor receptor bound protein 2 0.0027 0.0038 0.0044
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0031 0.006 0.0068
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0144 0.0514
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0144 0.0514
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.0015 0.0016
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0049 0.0144 0.0526
Loa Loa (eye worm) hypothetical protein 0.0091 0.0347 0.0347
Giardia lamblia Thioredoxin reductase 0.0022 0.0015 0.0024
Toxoplasma gondii thioredoxin reductase 0.0216 0.0942 0.4551
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.005 0.015 0.0197
Schistosoma mansoni kinase 0.0209 0.0911 0.12
Loa Loa (eye worm) oxidoreductase 0.0091 0.0347 0.0347
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0022 0.0044
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0022 0.0015 0.0029
Toxoplasma gondii ck2 beta subunit 0.0071 0.0252 0.1171
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0022 0.0015 0.0012
Entamoeba histolytica PH domain containing protein kinase, putative 0.0128 0.0522 0.1975
Loa Loa (eye worm) RecQ helicase 0.0092 0.0353 0.0353
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0124 0.0504 0.1496
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0055 0.0062
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0031 0.006 0.0068
Echinococcus multilocularis aldo keto reductase 0.0091 0.0347 0.0467
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0091 0.0347 0.0467
Echinococcus multilocularis cysteine protease atg4b 0.0058 0.0186 0.0246
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0148 0.062 0.062
Echinococcus granulosus Solute carrier family 22 5 0.101 0.4743 0.6473
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0022 0.0014 0.0007
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0112 0.0312
Schistosoma mansoni hypothetical protein 0.0028 0.0046 0.005
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0054 0.0169 0.0481
Schistosoma mansoni chromobox protein 0.0068 0.0236 0.0302
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0035 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0028 0.0046 0.0046
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0189 0.0543
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0202 0.0583
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0064 0.0218 0.1001
Echinococcus granulosus phd:f box containing protein 0.0044 0.0123 0.016
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Echinococcus granulosus lysosomal alpha glucosidase 0.022 0.0965 0.131
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0049 0.0146 0.0412
Echinococcus multilocularis chromobox protein 1 0.0068 0.0236 0.0314
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0193 0.0835 0.2497
Trichomonas vaginalis rotamase, putative 0.0033 0.0066 0.0215
Echinococcus granulosus phosphoglycerate kinase 1 0.0166 0.0705 0.0955
Schistosoma mansoni atypical protein kinase C 0.0049 0.0144 0.0179
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0144 0.0408
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0093 0.0316
Brugia malayi MAP kinase sur-1 0.0076 0.0273 0.081
Trypanosoma cruzi casein kinase II, putative 0.0138 0.057 0.1695
Schistosoma mansoni tyrosine kinase 0.0238 0.1051 0.1386
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.005 0.015 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0026 0.0062
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0049 0.0146 0.0412
Echinococcus granulosus glutamate synthase 0.0022 0.0015 0.0012
Onchocerca volvulus 0.0091 0.0347 0.1224
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0144 0.0514
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0147 0.0614 0.4737
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0076 0.0273 0.0798
Echinococcus multilocularis epidermal growth factor receptor 0.0284 0.1271 0.1728
Trichomonas vaginalis maltase-glucoamylase, putative 0.0049 0.0144 0.0514
Loa Loa (eye worm) inositol-1 0.0069 0.0241 0.0241
Brugia malayi Pre-SET motif family protein 0.0204 0.0888 0.2665
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0352 0.1596 0.5734
Brugia malayi Protein kinase domain containing protein 0.0031 0.006 0.0166
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0026 0.0028
Schistosoma mansoni tyrosine kinase 0.036 0.1634 0.216
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.0213 0.0615
Mycobacterium leprae Possible oxidoreductase 0.0026 0.0037 0.0244
Entamoeba histolytica protein kinase, putative 0.013 0.0531 0.2007
Schistosoma mansoni 6-phosphofructokinase 0.0147 0.0614 0.0804
Entamoeba histolytica peptidase, C54 family 0.0022 0.0018 0.0041
Echinococcus granulosus aurora kinase A 0.013 0.0531 0.0718
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0566 0.2617 1
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0016
Echinococcus multilocularis activin receptor type 0.0023 0.002 0.0019
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0061 0.02 0.0265
Schistosoma mansoni tyrosine kinase 0.036 0.1634 0.216
Echinococcus multilocularis glutathione S transferase 0.0057 0.0184 0.0243
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0015 0.0016
Plasmodium vivax multidomain scavenger receptor, putative 0.0038 0.0094 0.071
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0042 0.0111 0.0144
Entamoeba histolytica DNA topoisomerase II, putative 0.0192 0.0829 0.3148
Onchocerca volvulus 0.0127 0.052 0.1847
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0027 0.0038 0.0039
Echinococcus granulosus roundabout 2 0.0023 0.0019 0.0018
Trypanosoma cruzi phosphotransferase, putative 0.0065 0.0222 0.0643
Brugia malayi Cyclin, N-terminal domain containing protein 0.0048 0.0138 0.0403
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0057
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0112 0.0392
Schistosoma mansoni disulfide oxidoreductase 0.0022 0.0015 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0098 0.0657
Mycobacterium tuberculosis Probable oxidoreductase 0.0092 0.0351 0.2656
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0071 0.0252 0.094
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0609 0.2296
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0148 0.062 0.1845
Echinococcus multilocularis protein tyrosine kinase 0.0261 0.1159 0.1576
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0054 0.0169 0.0222
Echinococcus granulosus cyclins 0.0048 0.0138 0.0181
Trypanosoma brucei aldo-keto reductase, putative 0.0091 0.0347 0.1022
Onchocerca volvulus Tyrosine kinase homolog 0.0326 0.147 0.5278
Echinococcus multilocularis cyclin dependent kinase 0.0049 0.0146 0.0191
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0712 0.3317 1
Echinococcus multilocularis cyclins 0.0048 0.0138 0.0181
Echinococcus multilocularis cpg binding protein 0.0059 0.0194 0.0257
Plasmodium falciparum DNA gyrase subunit A 0.0286 0.128 0.6209
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.002 0.0045
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0058 0.0186 0.0533
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0087 0.0325 0.1525
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Onchocerca volvulus 0.009 0.0341 0.12
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0251 0.1112 0.3334
Echinococcus granulosus cyclins 0.0048 0.0138 0.0181
Echinococcus multilocularis glutathione S transferase 0.0062 0.0209 0.0278
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0146 0.0609 0.1812
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0146 0.0609 0.0824
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0705 0.2665
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.0015 0.0016
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0124 0.0504 0.392
Trichomonas vaginalis phosphofructokinase, putative 0.004 0.01 0.0346
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0021 0.001 0.0012
Echinococcus granulosus carbonic anhydrase 0.0448 0.2053 0.2797
Schistosoma mansoni tyrosine kinase 0.0269 0.1197 0.158
Echinococcus granulosus intermediate filament protein 0.0026 0.0036 0.0042
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0022 0.0044
Brugia malayi Flap endonuclease-1 0.0025 0.0032 0.0082
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0214 0.0932 0.7252
Schistosoma mansoni aldo-keto reductase 0.0091 0.0347 0.045
Onchocerca volvulus 0.0038 0.0094 0.0309
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0112 0.0774
Mycobacterium ulcerans DNA gyrase subunit B 0.0203 0.0882 0.6857
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0039 0.0098 0.0412
Echinococcus multilocularis aldo keto reductase 0.0091 0.0347 0.0467
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0031 0.006 0.006
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0028 0.0043 0.0051
Loa Loa (eye worm) AGC/PKN protein kinase 0.0035 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0014
Schistosoma mansoni polycystin 1-related 0.0038 0.0094 0.0114
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0112 0.0404
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0202 0.0583
Trypanosoma brucei trypanothione reductase 0.0216 0.0942 0.2819
Chlamydia trachomatis DNA gyrase subunit B 0.0144 0.0599 0.4616
Entamoeba histolytica protein kinase, putative 0.0023 0.0023 0.0059
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0031 0.006 0.0074
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Schistosoma mansoni flap endonuclease-1 0.0023 0.002 0.0015
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.005 0.015 0.0197
Brugia malayi hypothetical protein 0.0022 0.0014 0.0027
Brugia malayi Fibronectin type III domain containing protein 0.0024 0.0024 0.0056
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0061 0.0201 0.0593
Giardia lamblia DINP protein human, muc B family 0.0058 0.0189 0.0997
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0076 0.0089
Echinococcus multilocularis lysine specific demethylase 5A 0.0167 0.0707 0.0958
Giardia lamblia Glutamate synthase 0.0022 0.0015 0.0024
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0053 0.0164 0.118
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0049 0.0144 0.0514
Onchocerca volvulus 0.0069 0.024 0.0836
Echinococcus multilocularis Polycystic kidney disease protein 0.0038 0.0094 0.0121
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Loa Loa (eye worm) CXXC zinc finger family protein 0.0054 0.0167 0.0167
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0705 0.2103
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0061 0.0201 0.058
Brugia malayi Protein kinase domain containing protein 0.0049 0.0146 0.0425
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0712 0.3317 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0069 0.0241 0.0884
Brugia malayi hypothetical protein 0.0022 0.0014 0.0027
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0022 0.0015 0.0016
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.0019 0.0013
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0138 0.057 0.4437
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0273 0.1009
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Entamoeba histolytica disulphide oxidoreductase, putative 0.0022 0.0015 0.0029
Entamoeba histolytica hypothetical protein 0.0035 0.0078 0.0273
Trichomonas vaginalis cyclin B, putative 0.009 0.0341 0.1269
Echinococcus multilocularis titin 0.0021 0.0009 0.0004
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.005 0.015 0.0197
Loa Loa (eye worm) variant SH3 domain-containing protein 0.002 0.0005 0.0005
Plasmodium vivax aspartyl protease, putative 0.0022 0.0014 0.0077
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0193 0.0834 0.8936
Brugia malayi exonuclease family protein 0.0029 0.005 0.0137
Echinococcus granulosus insulin receptor 0.036 0.1634 0.2225
Schistosoma mansoni hypothetical protein 0.0036 0.0082 0.0097
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0061 0.0201 0.0267
Plasmodium vivax glycogen synthase kinase 3, putative 0.0054 0.0169 0.1291
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0015 0.0016
Brugia malayi Furin-like cysteine rich region family protein 0.0419 0.1915 0.5767
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0076 0.0089
Trichomonas vaginalis cyclin B, putative 0.009 0.0341 0.1269
Echinococcus multilocularis lipoxygenase domain containing protein 0.0038 0.0094 0.0121
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0148 0.062 0.1845
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0201 0.058
Echinococcus multilocularis glutathione S transferase 0.0057 0.0184 0.0243
Trichomonas vaginalis phosphofructokinase, putative 0.0147 0.0614 0.2315
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0052 0.0158 0.0208
Schistosoma mansoni ap endonuclease 0.0042 0.0112 0.0138
Schistosoma mansoni memapsin-2 (A01 family) 0.0538 0.2485 0.3292
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0023 0.002 0.0032
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0236 0.0865
Schistosoma mansoni rotamase 0.0033 0.0066 0.0076
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0124 0.0504 0.1507
Echinococcus granulosus thioredoxin glutathione reductase 0.0217 0.0948 0.1287
Leishmania major alpha glucosidase II subunit, putative 0.0049 0.0144 0.0408
Toxoplasma gondii AGC kinase 0.0124 0.0504 0.2405
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0031 0.006 0.0203
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0061 0.02 0.0913
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0037 0.0102
Leishmania major squalene monooxygenase-like protein 0.0244 0.1076 0.3224
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0146 0.0519
Trichomonas vaginalis glutaminase, putative 0.0267 0.1187 0.4513
Plasmodium falciparum protein kinase, putative 0.0023 0.002 0.003
Echinococcus granulosus glutathione S transferase 0.0062 0.0209 0.0278
Trypanosoma cruzi NADH dehydrogenase, putative 0.0022 0.0015 0.0016
Echinococcus multilocularis carbonic anhydrase 0.0448 0.2053 0.2797
Trichomonas vaginalis CMGC family protein kinase 0.0138 0.057 0.2147
Toxoplasma gondii hypothetical protein 0.0448 0.2053 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0091 0.0347 0.1294
Loa Loa (eye worm) bromodomain containing protein 0.0024 0.0025 0.0025
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Plasmodium falciparum phosphoglycerate kinase 0.0166 0.0705 0.339
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0107 0.0353
Leishmania major protein kinase A catalytic subunit 0.0124 0.0504 0.1496
Trypanosoma brucei DNA polymerase IV, putative 0.0071 0.0251 0.0732
Loa Loa (eye worm) CAMK protein kinase 0.0021 0.0009 0.0009
Schistosoma mansoni terminal deoxycytidyl transferase 0.0052 0.0158 0.0198
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0124 0.0504 0.0681
Schistosoma mansoni glutamate synthase 0.0022 0.0015 0.0008
Schistosoma mansoni cpg binding protein 0.0054 0.0167 0.021
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0202 0.0583
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0091 0.0347 0.0467
Brugia malayi hypothetical protein 0.0038 0.0094 0.027
Plasmodium vivax aspartyl proteinase, putative 0.0022 0.0014 0.0077
Mycobacterium tuberculosis Conserved protein 0.0026 0.0037 0.0177
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0061 0.0201 0.058
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0057 0.0185 0.0532
Giardia lamblia G2/mitotic-specific cyclin B 0.009 0.0341 0.1846
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0071 0.0252 0.0735
Schistosoma mansoni protein kinase 0.0023 0.002 0.0015
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0022 0.0015 0.0016
Mycobacterium ulcerans oxidoreductase 0.0091 0.0347 0.2632
Trypanosoma cruzi trypanothione reductase, putative 0.0061 0.0201 0.058
Leishmania major phosphoglycerate kinase B, cytosolic 0.0166 0.0705 0.2103
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0084 0.0311 0.0418
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0176 0.0751 0.2243
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0053 0.0164 0.118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0201 0.058
Giardia lamblia Cyclin A 0.0048 0.0138 0.0714
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.018
Echinococcus multilocularis tyrosine protein kinase Srms 0.0088 0.0332 0.0446
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0022 0.0015 0.0083
Plasmodium falciparum aldehyde reductase, putative 0.0026 0.0037 0.0114
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0124 0.0504 0.2405
Loa Loa (eye worm) hypothetical protein 0.0055 0.0174 0.0174
Brugia malayi SH2 domain containing protein 0.0031 0.006 0.0166
Schistosoma mansoni inositol monophosphatase 0.0069 0.0241 0.0308
Brugia malayi Tyrosine-protein kinase abl-1 0.0042 0.0111 0.0322
Trichomonas vaginalis phosphofructokinase, putative 0.0147 0.0614 0.2315
Schistosoma mansoni protein kinase 0.013 0.0531 0.0694
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0024
Trichomonas vaginalis AGC family protein kinase 0.013 0.0531 0.1997
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0021 0.001 0.0012
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0147 0.0614 0.1828
Brugia malayi hypothetical protein 0.0599 0.2777 0.837
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0022 0.0014 0.0007
Brugia malayi glutaminase DH11.1 0.0267 0.1187 0.3568
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0112 0.0312
Echinococcus multilocularis carbonic anhydrase 0.0448 0.2053 0.2797
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0069 0.0241 0.0884
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0026 0.0037 0.0083
Loa Loa (eye worm) carbonic anhydrase 3 0.0712 0.3317 0.3317
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0032 0.0089
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0284 0.1271 0.1728
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0034 0.0071 0.0083
Echinococcus granulosus titin 0.0021 0.0009 0.0004
Echinococcus multilocularis glutathione S transferase 0.0045 0.0124 0.0161
Trichomonas vaginalis cyclins, putative 0.009 0.0341 0.1269
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0019 0.0031
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0124 0.0504 0.2405
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0531 0.0694
Echinococcus multilocularis cyclin B3 1 0.0048 0.0138 0.0181
Brugia malayi serine/threonine-protein kinase plk-2 0.0146 0.0609 0.1823
Entamoeba histolytica phosphofructokinase, putative 0.0147 0.0614 0.2325
Brugia malayi Doublecortin family protein 0.0038 0.0094 0.027
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0039 0.0098 0.0657
Loa Loa (eye worm) TK/EGFR protein kinase 0.0419 0.1915 0.1915
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0124 0.0504 0.1496
Brugia malayi Protein kinase domain containing protein 0.0031 0.006 0.0166
Echinococcus granulosus tyrosine protein kinase Fyn 0.0099 0.0384 0.0516
Brugia malayi Protein kinase domain containing protein 0.036 0.1634 0.4919
Plasmodium falciparum casein kinase II beta chain 0.0071 0.0252 0.1171
Entamoeba histolytica protein kinase, putative 0.0072 0.0256 0.0954
Schistosoma mansoni growth factor receptor-bound protein 0.0027 0.0038 0.0039
Brugia malayi protein kinase C3,putative 0.0022 0.0014 0.0028
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0031 0.006 0.0074
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0032 0.0083
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0061 0.0201 0.058
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0045 0.0108
Leishmania major phosphoglycerate kinase C, glycosomal 0.0166 0.0705 0.2103
Schistosoma mansoni hypothetical protein 0.0202 0.0877 0.1154
Trichomonas vaginalis AGC family protein kinase 0.013 0.0531 0.1997
Loa Loa (eye worm) hypothetical protein 0.0031 0.006 0.006
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0071 0.0252 0.094
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.0015 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0609 0.2296
Entamoeba histolytica alcohol dehydrogenase, putative 0.0026 0.0037 0.0115
Schistosoma mansoni growth factor receptor-bound protein 0.0027 0.0038 0.0039
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0099 0.0384 0.0516
Schistosoma mansoni hypothetical protein 0.0031 0.006 0.0068
Echinococcus multilocularis carbonic anhydrase 0.0448 0.2053 0.2797
Treponema pallidum ATP-dependent DNA helicase 0.0033 0.0067 0.0294
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0091 0.0347 0.1034
Loa Loa (eye worm) hypothetical protein 0.0053 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0028 0.0043 0.0043
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0022 0.0015 0.0004
Echinococcus granulosus nervana 2 0.0053 0.0164 0.0216
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0216 0.0942 0.7328
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0022 0.0018 0.0025
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0031 0.006 0.0167
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0076 0.0251
Brugia malayi Peptidase family C54 containing protein 0.0058 0.0186 0.0546
Plasmodium falciparum aldo-keto reductase, putative 0.0026 0.0037 0.0114
Brugia malayi 6-phosphofructokinase 0.0147 0.0614 0.1839
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0022 0.0044
Echinococcus granulosus tyrosine protein kinase Src42A 0.0073 0.0259 0.0346
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0169 0.0719 0.0974
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0241 0.0699
Echinococcus multilocularis lysine specific demethylase 6a 0.0044 0.0123 0.016
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0148 0.0617 0.2197
Mycobacterium tuberculosis Probable reductase 0.0053 0.0164 0.118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0061 0.0201 0.058
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0273 0.1009
Brugia malayi SH2 domain containing protein 0.0031 0.006 0.0166
Schistosoma mansoni cpg binding protein 0.0059 0.0194 0.0246
Brugia malayi N-terminal motif family protein 0.0352 0.1596 0.4804
Echinococcus granulosus neutral alpha glucosidase AB 0.0049 0.0144 0.0189
Echinococcus multilocularis growth factor receptor bound protein 2 0.0027 0.0038 0.0044
Schistosoma mansoni 6-phosphofructokinase 0.0147 0.0614 0.0804
Brugia malayi RhoGAP domain containing protein 0.003 0.0054 0.0149
Schistosoma mansoni DNA helicase recq1 0.0064 0.0218 0.0278
Brugia malayi ImpB/MucB/SamB family protein 0.0052 0.0158 0.0463
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0058 0.0186 0.0533
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0036
Plasmodium vivax protein kinase Crk2 0.0049 0.0146 0.1111
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0123 0.0123
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0144 0.0179
Echinococcus granulosus jumonji domain containing 1A 0.0044 0.0123 0.016
Onchocerca volvulus 0.0022 0.0014 0.0018
Echinococcus granulosus JmjC domain containing protein 4 0.0044 0.0123 0.016
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0148 0.062 0.1845
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0054 0.017 0.1227
Loa Loa (eye worm) hypothetical protein 0.0052 0.0159 0.0159
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.0282 0.0825
Entamoeba histolytica hypothetical protein 0.0023 0.0019 0.0048
Loa Loa (eye worm) hypothetical protein 0.0599 0.2777 0.2777
Trypanosoma cruzi DNA topoisomerase II, putative 0.0176 0.0751 0.2243
Echinococcus multilocularis dna polymerase kappa 0.0078 0.0282 0.0378
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0036 0.0036
Schistosoma mansoni tyrosine kinase 0.0269 0.1197 0.158
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0163 0.0587
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0031 0.006 0.0074
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0061 0.02 0.0265
Loa Loa (eye worm) hypothetical protein 0.0061 0.0202 0.0202
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Echinococcus granulosus prostaglandin H2 D isomerase 0.0023 0.0021 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0112 0.031
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0078 0.0092
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0176 0.0751 0.2243
Echinococcus granulosus serine:threonine protein kinase 12 B 0.013 0.0531 0.0718
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0148 0.062 0.2347
Leishmania major casein kinase II, putative 0.0138 0.057 0.1695
Echinococcus multilocularis protein kinase c iota type 0.0049 0.0144 0.0188
Trypanosoma cruzi cdc2-related kinase 3 0.0049 0.0146 0.0412
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0061 0.0201 0.058
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0022 0.0015 0.0004
Echinococcus granulosus carbonic anhydrase 0.0448 0.2053 0.2797
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0202 0.0583
Loa Loa (eye worm) hypothetical protein 0.0139 0.0577 0.0577
Schistosoma mansoni cyclin B 0.009 0.0341 0.0442
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.007 0.0246 0.0715
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0078 0.0282 0.1044
Entamoeba histolytica peptidase, C54 family 0.0022 0.0018 0.0041
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0117 0.0468 0.0632
Entamoeba histolytica hypothetical protein 0.0024 0.0026 0.0074
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1022 0.3881
Brugia malayi serine/threonine-protein kinase 6 0.013 0.0531 0.1588
Schistosoma mansoni ephrin receptor 0.0069 0.0239 0.0306
Echinococcus granulosus cyclin dependent kinase 0.0049 0.0146 0.0191
Trichomonas vaginalis DNA helicase recq1, putative 0.0092 0.0353 0.1313
Echinococcus multilocularis casein kinase ii subunit beta 0.0071 0.0252 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0609 0.2296
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.003 0.0054 0.006
Echinococcus multilocularis glutathione S-transferase 0.0062 0.0209 0.0278
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0049 0.0144 0.0188
Plasmodium vivax aldehyde reductase, putative 0.0026 0.0037 0.0259
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0099 0.0384 0.0516
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0107 0.0369
Loa Loa (eye worm) AGC/AKT protein kinase 0.0091 0.0348 0.0348
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0032 0.0036
Leishmania major importin beta-1 subunit, putative 0.0023 0.0019 0.0031
Onchocerca volvulus 0.0041 0.0109 0.036
Trichomonas vaginalis phosphofructokinase, putative 0.004 0.01 0.0346
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0186 0.0673
Trypanosoma cruzi aldo-keto reductase 0.0091 0.0347 0.1022
Trichomonas vaginalis phosphofructokinase, putative 0.004 0.01 0.0346
Brugia malayi Heterochromatin protein 1 0.0068 0.0236 0.0697
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0024 0.0056
Trichomonas vaginalis cyclins, putative 0.0054 0.0168 0.0606
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0061 0.0201 0.092
Trichomonas vaginalis phosphofructokinase, putative 0.0147 0.0614 0.2315
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0026 0.0051
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0076 0.0273 0.1272
Loa Loa (eye worm) AGC/PKA protein kinase 0.0124 0.0504 0.0504
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0109 0.0133
Loa Loa (eye worm) AUR protein kinase 0.013 0.0531 0.0531
Loa Loa (eye worm) hypothetical protein 0.0124 0.0504 0.0504
Trichomonas vaginalis AGC family protein kinase 0.0124 0.0504 0.1894
Trypanosoma brucei protein kinase, putative 0.0054 0.0169 0.0481
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0026 0.0037 0.0114
Brugia malayi Inositol-1 0.0069 0.0241 0.0712
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0022 0.0015 0.0016
Brugia malayi hypothetical protein 0.0024 0.0024 0.0056
Chlamydia trachomatis DNA gyrase subunit A 0.0286 0.128 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0027 0.0038 0.0038
Echinococcus multilocularis cyclins 0.0048 0.0138 0.0181
Schistosoma mansoni cyclins 0.0048 0.0138 0.0172
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0061 0.0201 0.1476
Echinococcus multilocularis muscleblind protein 1 0.0056 0.018 0.0238
Echinococcus multilocularis roundabout 2 0.0023 0.0019 0.0018
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0019 0.0035
Schistosoma mansoni serine/threonine-protein kinase 0.0066 0.0225 0.0287
Brugia malayi serine/threonine protein kinase 6 0.013 0.0531 0.1588
Trypanosoma cruzi squalene monooxygenase, putative 0.0244 0.1076 0.3224
Echinococcus multilocularis tyrosine protein kinase Abl 0.0042 0.0111 0.0144
Entamoeba histolytica peptidase, C54 family 0.0022 0.0018 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0216 0.0942 0.2819
Echinococcus multilocularis bloom syndrome protein 0.0092 0.0353 0.0474
Trypanosoma cruzi DNA polymerase eta, putative 0.0077 0.0277 0.0809
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0169 0.0607
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0202 0.0583
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0023 0.002 0.0019
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0448 0.2053 0.6182
Brugia malayi intracellular kinase 0.0054 0.0169 0.0494
Echinococcus multilocularis aldehyde reductase 0.0065 0.0221 0.0294
Mycobacterium tuberculosis Conserved hypothetical protein 0.0215 0.094 0.7315
Mycobacterium ulcerans hypothetical protein 0.0026 0.0037 0.0177
Mycobacterium ulcerans hypothetical protein 0.0215 0.094 0.7315
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0069 0.0241 0.0884
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0091 0.0347 0.0467
Echinococcus granulosus serine:threonine protein kinase N2 0.0035 0.0076 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0111 0.0309
Echinococcus granulosus cyclins 0.0048 0.0138 0.0181
Plasmodium vivax DNA topoisomerase II, putative 0.0192 0.0829 0.6465
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0468 0.0468
Echinococcus granulosus protein tyrosine kinase 0.0261 0.1159 0.1576
Echinococcus multilocularis tyrosine protein kinase Blk 0.0088 0.0332 0.0446
Brugia malayi serine/threonine kinase 12 0.013 0.0531 0.1588
Echinococcus multilocularis transcription factor Dp 1 0.0086 0.0321 0.0431
Onchocerca volvulus 0.0054 0.0167 0.0572
Brugia malayi jmjC domain containing protein 0.0172 0.0734 0.2201
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0022 0.0014 0.0013
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0054 0.0169 0.0222
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Plasmodium vivax aspartyl proteinase, putative 0.0022 0.0014 0.0077
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0015 0.0016
Echinococcus multilocularis phosphoglycerate kinase 1 0.0166 0.0705 0.0955
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0022 0.0015 0.0012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0022 0.0014 0.0007
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0023 0.0021 0.002
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0022 0.0014 0.0011
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0045 0.0054
Trichomonas vaginalis cyclin B3, putative 0.0048 0.0138 0.0491
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0053 0.0164 0.118
Schistosoma mansoni lamin 0.0026 0.0036 0.0036
Echinococcus granulosus contactin 0.0023 0.0019 0.0018
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0064 0.0218 0.0643
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0348 0.1295
Entamoeba histolytica recQ family helicase, putative 0.0032 0.0061 0.0207
Loa Loa (eye worm) TK protein kinase 0.0088 0.0332 0.0332
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0609 0.2296
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0048 0.0138 0.0181
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0141 0.0176
Echinococcus granulosus peregrin 0.0032 0.0062 0.0077
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.0015 0.0029
Echinococcus granulosus tyrosine protein kinase Src42A 0.0099 0.0384 0.0516
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0163 0.0587
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0023 0.002 0.0032
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0026 0.0037 0.0097
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0022 0.0014 0.0007
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0091 0.0347 0.3629
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0035 0.0076 0.0096
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0192 0.0829 0.2487
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0169 0.0607
Loa Loa (eye worm) thioredoxin reductase 0.0216 0.0942 0.0942
Echinococcus multilocularis roundabout 2 0.0023 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0119 0.048 0.048
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.013 0.0531 0.2007
Brugia malayi Protein kinase domain containing protein 0.0155 0.065 0.1949
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0092 0.0351 0.2656
Entamoeba histolytica hypothetical protein 0.0035 0.0078 0.0273
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Plasmodium vivax casein kinase II beta chain, putative 0.0071 0.0252 0.1948
Echinococcus granulosus N chimaerin 0.003 0.0054 0.0066
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0123 0.0123
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0036 0.0095
Echinococcus multilocularis 0.0123 0.0501 0.0677
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0055 0.0068
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0032 0.0032
Leishmania major mitochondrial DNA polymerase beta 0.0409 0.1865 0.561
Echinococcus granulosus 6 phosphofructokinase 0.0147 0.0614 0.0831
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0076 0.0273 0.0273
Trypanosoma cruzi squalene monooxygenase, putative 0.0244 0.1076 0.3224
Schistosoma mansoni carbonic anhydrase 0.0448 0.2053 0.2717
Brugia malayi MH2 domain containing protein 0.0117 0.0468 0.1397
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.006 0.006
Entamoeba histolytica cyclin, putative 0.0048 0.0138 0.0502
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0069 0.0241 0.0699
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0023 0.002 0.0019
Echinococcus multilocularis neuroglian 0.0026 0.0033 0.0038
Giardia lamblia Phosphoglycerate kinase 0.0166 0.0705 0.3877
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0609 0.0797
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0061 0.0201 0.0256
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0076 0.0251
Entamoeba histolytica aldose reductase, putative 0.0091 0.0347 0.1304
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0609 0.2296
Loa Loa (eye worm) hypothetical protein 0.0038 0.0093 0.0093
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0144 0.0514
Loa Loa (eye worm) hypothetical protein 0.009 0.0341 0.0341
Entamoeba histolytica peptidase, C54 family 0.0058 0.0186 0.0684
Echinococcus multilocularis c src tyrosine kinase 0.0042 0.0111 0.0144
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0409 0.1865 0.561
Loa Loa (eye worm) hypothetical protein 0.0033 0.0067 0.0067
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0048 0.0138 0.0181
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0073 0.0259 0.0346
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0213 0.0283
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0049 0.0146 0.0146
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0022 0.0015 0.0083
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0022 0.0015 0.0012
Giardia lamblia Kinase, AGC PKA 0.0124 0.0504 0.2756
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Echinococcus granulosus cyclin b3 0.0048 0.0138 0.0181
Echinococcus multilocularis Protein lozenge 0.0075 0.027 0.0361
Brugia malayi Protein kinase domain containing protein 0.0022 0.0014 0.0028
Echinococcus multilocularis lipoxygenase domain containing protein 0.0038 0.0094 0.0121
Echinococcus granulosus tyrosine protein kinase Srms 0.0031 0.006 0.0074
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0193 0.0834 0.648
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0193 0.0834 0.648
Echinococcus multilocularis serine:threonine protein kinase N2 0.0035 0.0076 0.0096
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0026 0.0037 0.0114
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.0189 0.0543
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Mycobacterium tuberculosis Conserved hypothetical protein 0.0052 0.0158 0.1135
Leishmania major protein kinase A catalytic subunit isoform 2 0.0124 0.0504 0.1496
Loa Loa (eye worm) hypothetical protein 0.0599 0.2777 0.2777
Schistosoma mansoni protein kinase 0.0023 0.002 0.0015
Schistosoma mansoni hypothetical protein 0.0028 0.0044 0.0047
Schistosoma mansoni lipoxygenase 0.01 0.0387 0.0503
Schistosoma mansoni methyl-cpg binding protein mbd 0.0023 0.0021 0.0016
Schistosoma mansoni apoptosis regulator bax 0.0031 0.006 0.0068
Brugia malayi glutamate synthase 0.0022 0.0015 0.0029
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0202 0.0583
Schistosoma mansoni intermediate filament proteins 0.0026 0.0036 0.0036
Onchocerca volvulus 0.0022 0.0015 0.0021
Trypanosoma cruzi cyclin, putative 0.009 0.0341 0.1003
Echinococcus granulosus neuroglian 0.0023 0.0019 0.0018
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0026 0.0037 0.0259
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0049 0.0146 0.0146
Schistosoma mansoni chromobox protein 0.0068 0.0236 0.0302
Onchocerca volvulus Alhambra homolog 0.0028 0.0046 0.0136
Echinococcus multilocularis Glutaredoxin protein 5 0.0054 0.017 0.0225
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0186 0.0673
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0054 0.0168 0.0756
Echinococcus multilocularis protein kinase c epsilon type 0.0049 0.0144 0.0188
Entamoeba histolytica aldose reductase, putative 0.0091 0.0347 0.1304
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0115 0.046 0.06
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0064 0.0218 0.029
Schistosoma mansoni hypothetical protein 0.0165 0.0701 0.0921
Loa Loa (eye worm) TK/ABL protein kinase 0.0031 0.006 0.006
Echinococcus multilocularis glutathione S transferase 0.0045 0.0124 0.0161
Echinococcus granulosus glutathione S transferase 0.0045 0.0124 0.0161
Giardia lamblia Casein kinase II beta chain 0.0071 0.0252 0.1351
Mycobacterium ulcerans DNA polymerase IV 0.0078 0.0282 0.2116
Trichomonas vaginalis DNA helicase recq, putative 0.0092 0.0353 0.1313
Plasmodium falciparum DNA topoisomerase 2 0.0192 0.0829 0.3997
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0019
Onchocerca volvulus 0.0599 0.2777 1
Loa Loa (eye worm) oxidoreductase 0.0091 0.0347 0.0347
Trypanosoma cruzi DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0042 0.0111 0.0136
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0042 0.0111 0.0111
Entamoeba histolytica protein kinase, putative 0.013 0.0531 0.2007
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0049 0.0144 0.0526
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0192 0.0829 0.1124
Echinococcus granulosus mitogen activated protein kinase 3 0.0076 0.0273 0.0365
Loa Loa (eye worm) hypothetical protein 0.0058 0.0186 0.0186
Loa Loa (eye worm) 6-phosphofructokinase 0.0147 0.0614 0.0614
Echinococcus multilocularis Peptidase C54 0.0058 0.0186 0.0246
Echinococcus multilocularis cyclin dependent kinase 5 0.0049 0.0146 0.0191
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0062 0.0206 0.1513
Trichomonas vaginalis glutathione reductase, putative 0.0061 0.0201 0.0733
Schistosoma mansoni lozenge 0.0075 0.027 0.0347
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0038 0.01
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.009 0.0341 0.1003
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0061 0.0201 0.1476
Brugia malayi 6-phosphofructokinase 0.0147 0.0614 0.1839
Loa Loa (eye worm) hypothetical protein 0.0048 0.0141 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0609 0.2296
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0144 0.0179
Brugia malayi Protein kinase c protein 2 0.0022 0.0014 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0166 0.0209
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.0015 0.0012
Loa Loa (eye worm) doublecortin family protein 0.0038 0.0094 0.0094
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0044 0.0123 0.0535
Echinococcus granulosus protein kinase shaggy 0.0054 0.0169 0.0222
Onchocerca volvulus 0.0091 0.0347 0.1224
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.1023 0.1348
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0124 0.0504 0.0681
Toxoplasma gondii DNA topoisomerase 2, putative 0.0192 0.0829 0.3997
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0054 0.0169 0.0169
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0057 0.0185 0.0532
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0053
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0076 0.0273 0.0798
Brugia malayi plexin A 0.002 0.0006 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Trichomonas vaginalis cyclin B, putative 0.009 0.0341 0.1269
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0169 0.0719 0.0974
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0049 0.0146 0.0191
Loa Loa (eye worm) oxidoreductase 0.0091 0.0347 0.0347
Echinococcus granulosus epidermal growth factor receptor 0.0284 0.1271 0.1728
Loa Loa (eye worm) runx1 0.0075 0.027 0.027
Echinococcus granulosus inositol monophosphatase 1 0.0069 0.0241 0.0321
Echinococcus granulosus roundabout 2 0.0023 0.0019 0.0018
Leishmania major protein kinase, putative 0.0023 0.002 0.0032
Giardia lamblia DNA topoisomerase II 0.0181 0.0776 0.4275
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0282 0.0825
Trypanosoma cruzi Protein kinase B 0.0064 0.0218 0.0632
Echinococcus granulosus cyclins 0.0048 0.0138 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0076 0.0089
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0091 0.0347 0.1294
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Plasmodium falciparum glutathione reductase 0.0216 0.0942 0.4551
Trichomonas vaginalis aldo-keto reductase, putative 0.0091 0.0347 0.1294
Echinococcus multilocularis casein kinase ii subunit alpha 0.0138 0.057 0.0771
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0061 0.0201 0.058
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0112 0.0146
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0071 0.0252 0.088
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0286 0.128 0.6209
Schistosoma mansoni ap endonuclease 0.0042 0.0112 0.0138
Leishmania major DNA topoisomerase ii 0.0176 0.0751 0.2243
Echinococcus granulosus muscleblind protein 0.0056 0.018 0.0238
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0091 0.0347 0.1034
Trypanosoma brucei aurora B kinase 0.013 0.0531 0.1577
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.004 0.01 0.0679
Brugia malayi Protein kinase domain containing protein 0.0035 0.0076 0.0214
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0112 0.057
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.003 0.0054 0.006
Plasmodium falciparum protein kinase 5 0.0049 0.0146 0.0647
Trichomonas vaginalis cyclin B, putative 0.009 0.0341 0.1269
Echinococcus granulosus aldo keto reductase 0.0091 0.0347 0.0467
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0348 0.1295
Entamoeba histolytica cyclin, putative 0.009 0.0341 0.128
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0286 0.128 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.1348 0.1348
Echinococcus granulosus Peptidase C54 0.0058 0.0186 0.0246
Entamoeba histolytica alcohol dehydrogenase, putative 0.0026 0.0037 0.0115
Loa Loa (eye worm) exonuclease 0.0029 0.005 0.005
Onchocerca volvulus 0.0031 0.006 0.0185
Entamoeba histolytica cyclin family protein 0.0048 0.0138 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0093 0.0316
Schistosoma mansoni carbonic anhydrase-related 0.0448 0.2053 0.2717
Loa Loa (eye worm) hypothetical protein 0.0053 0.0165 0.0165
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0147 0.0614 0.6532
Echinococcus granulosus neuroglian 0.0026 0.0033 0.0038
Brugia malayi PHD-finger family protein 0.0028 0.0046 0.0125
Loa Loa (eye worm) hypothetical protein 0.0077 0.0277 0.0277
Echinococcus granulosus aldehyde reductase 0.0065 0.0221 0.0294
Entamoeba histolytica phosphofructokinase, putative 0.0147 0.0614 0.2325
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0395 0.1802 0.6877
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Echinococcus granulosus cyclins 0.0048 0.0138 0.0181
Brugia malayi Protein kinase domain containing protein 0.0264 0.1173 0.3527
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0146 0.0182
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0069 0.0241 0.0895
Onchocerca volvulus 0.0026 0.0037 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0076 0.0089
Entamoeba histolytica protein kinase, putative 0.0035 0.0076 0.0263
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0225 0.0988 0.1342
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0076 0.0273 0.0798
Mycobacterium ulcerans hypothetical protein 0.0039 0.0098 0.0657
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0186 0.0673
Echinococcus multilocularis aldo keto reductase 0.0091 0.0347 0.0467
Loa Loa (eye worm) hypothetical protein 0.0038 0.0094 0.0094
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0099 0.0384 0.0516
Loa Loa (eye worm) Csnk2b protein 0.0071 0.0252 0.0252
Echinococcus multilocularis raf serine:threonine protein kinase 0.0233 0.1023 0.139
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.015 0.0535
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.0015 0.0016
Schistosoma mansoni hypothetical protein 0.0365 0.1658 0.2192
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0146 0.0519
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0071 0.0252 0.094
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0146 0.0182
Trichomonas vaginalis casein kinase II beta chain, putative 0.0071 0.0252 0.0929
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0058 0.0186 0.0235
Echinococcus multilocularis jumonji domain containing protein 0.004 0.01 0.0128
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.0277 0.0822
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0192 0.0829 0.2487
Mycobacterium ulcerans hypothetical protein 0.0039 0.0098 0.0657
Schistosoma mansoni alpha-glucosidase 0.019 0.0818 0.1076
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0026 0.0062
Brugia malayi SRC-1 0.0099 0.0384 0.1144
Schistosoma mansoni hypothetical protein 0.0022 0.0015 0.0008
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.029 0.1296 0.1711
Giardia lamblia PHD finger protein 15 0.0028 0.0046 0.0202
Entamoeba histolytica deoxycytidyl transferase, putative 0.0052 0.0158 0.0579
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.013 0.0531 0.2007
Schistosoma mansoni casein kinase II beta subunit 0.0071 0.0252 0.0324
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0045 0.0108
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0078 0.0283 0.2931
Plasmodium falciparum DNA gyrase subunit B 0.0203 0.0882 0.4258
Trypanosoma brucei polo-like protein kinase 0.0146 0.0609 0.1812
Onchocerca volvulus 0.0091 0.0347 0.1224

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1200 nM Enzyme Assay BINDINGDB. No reference
IC50 (binding) = 1650 nM BindingDB_Patents: Enzyme Assay. P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compound plate to initiate the enzyme reaction; P70S6K (3 nM, T412E mutant, Millipore) is mixed with 24 µM ATP in an assay buffer containing 100 mM Hepes (pH 7.5), 5 mM MgCl2, 1 mM DTT, 0.015% Brij and 1 µM of the substrate peptide FITC-AHA-AKRRRLSSLRA-OH (derived from the S6 ribosomal protein sequence, FITC=fluorescein isothiocyanate, AHA=6-aminohexanoic acid). The reaction is incubated for 90 min at 25° C., before the addition of 10 mM EDTA to stop the reaction. The proportion of substrate and product (phosphorylated) peptide is analysed on a Caliper Life Sciences Lab Chip 3000, using a pressure of -1.4 psi, and upstream and downstream voltages of -3000 and -700 respectively. ChEMBL. No reference
IC50 (binding) = 1650 nM BindingDB_Patents: Enzyme Assay. P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compound plate to initiate the enzyme reaction; P70S6K (3 nM, T412E mutant, Millipore) is mixed with 24 µM ATP in an assay buffer containing 100 mM Hepes (pH 7.5), 5 mM MgCl2, 1 mM DTT, 0.015% Brij and 1 µM of the substrate peptide FITC-AHA-AKRRRLSSLRA-OH (derived from the S6 ribosomal protein sequence, FITC=fluorescein isothiocyanate, AHA=6-aminohexanoic acid). The reaction is incubated for 90 min at 25° C., before the addition of 10 mM EDTA to stop the reaction. The proportion of substrate and product (phosphorylated) peptide is analysed on a Caliper Life Sciences Lab Chip 3000, using a pressure of -1.4 psi, and upstream and downstream voltages of -3000 and -700 respectively. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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