Detailed information for compound 2077598

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 392.926 | Formula: C19H29ClN6O
  • H donors: 2 H acceptors: 4 LogP: 2.18 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(CCC1CCCC1)NCCn1nc(c2c1nccn2)C1CCNC1.Cl
  • InChi: 1S/C19H28N6O.ClH/c26-16(6-5-14-3-1-2-4-14)21-11-12-25-19-18(22-9-10-23-19)17(24-25)15-7-8-20-13-15;/h9-10,14-15,20H,1-8,11-13H2,(H,21,26);1H
  • InChiKey: RNCVIJQKFCXDQA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi trypanothione reductase, putative 0.011 0.1022 0.3618
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0083 0.0294
Trichomonas vaginalis CAMK family protein kinase 0.0086 0.0771 0.1328
Loa Loa (eye worm) hypothetical protein 0.0023 0.0123 0.0242
Onchocerca volvulus 0.0072 0.0629 0.1069
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0123 0.0242
Onchocerca volvulus 0.0116 0.1083 0.1854
Loa Loa (eye worm) tubulin alpha-3 chain 0.0121 0.1129 0.2221
Brugia malayi Ets-domain containing protein 0.008 0.0708 0.1394
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Brugia malayi Pre-SET motif family protein 0.0072 0.0629 0.1238
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0063 0.007
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0223 0.0789
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Echinococcus multilocularis tubulin subunit TubB 0.0206 0.2007 0.2007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0184 0.0362
Schistosoma mansoni twik family of potassium channels-related 0.0013 0.0015 0.0017
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0063 0.0063
Plasmodium falciparum potassium channel 0.0013 0.0015 0.0054
Trichomonas vaginalis penicillin-binding protein, putative 0.0116 0.1083 0.1868
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.001 0.0017
Brugia malayi acetyltransferase, GNAT family protein 0.0162 0.156 0.307
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0278 0.0984
Plasmodium falciparum thioredoxin reductase 0.0038 0.0278 0.0984
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0038 0.0278 0.0306
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0123 0.0136
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0118 0.0418
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0278 0.0984
Toxoplasma gondii NADPH-glutathione reductase 0.0038 0.0278 0.0984
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0038 0.0278 0.0984
Onchocerca volvulus 0.0013 0.0015 0.0009
Plasmodium falciparum glutathione reductase 0.0038 0.0278 0.0984
Loa Loa (eye worm) hypothetical protein 0.0023 0.0123 0.0242
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0013 0.0015 0.003
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.0173 0.021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0038 0.0278 0.0984
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0083 0.0092
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.0173 0.021
Brugia malayi Cytochrome P450 family protein 0.0071 0.0615 0.1209
Brugia malayi beta-tubulin, identical 0.0285 0.2825 0.5558
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.0173 0.021
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0012 0.0003 0.0006
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0072 0.0629 0.0629
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0126 0.0248
Trichomonas vaginalis tubulin, putative 0.0085 0.0761 0.1312
Trichomonas vaginalis DNA helicase recq1, putative 0.0048 0.0377 0.0649
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1997 0.3443
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0028 0.0173 0.1478
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0377 0.1333
Mycobacterium ulcerans lipase LipD 0.0116 0.1083 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0033 0.0223 0.0384
Schistosoma mansoni tubulin subunit beta 0.0285 0.2825 0.3113
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Echinococcus granulosus Tubulin beta 2C chain 0.0285 0.2825 0.3113
Trichomonas vaginalis tubulin, putative 0.0065 0.0557 0.096
Entamoeba histolytica tubulin family protein 0.0285 0.2825 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0251 0.2481 0.3272
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0083 0.0294
Echinococcus granulosus tubulin subunit beta 0.0285 0.2825 0.3113
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.2111 0.3639
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0013 0.0015 0.003
Echinococcus granulosus beta LACTamase domain containing family member 0.0116 0.1083 0.1194
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0038 0.0278 0.0984
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0123 0.0136
Trypanosoma cruzi tubulin delta chain 0.0065 0.0557 0.1972
Echinococcus multilocularis expressed protein 0.0452 0.4552 0.4552
Brugia malayi Tubulin gamma chain 0.015 0.1435 0.2823
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0086 0.0771 0.2728
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Onchocerca volvulus 0.0169 0.1632 0.28
Echinococcus multilocularis dna polymerase eta 0.0019 0.0083 0.0083
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0063 0.0125
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0126 0.0139
Loa Loa (eye worm) hypothetical protein 0.0023 0.0123 0.0242
Schistosoma mansoni ets-related 0.0012 0.0003 0.0003
Mycobacterium ulcerans cell division protein FtsZ 0.0065 0.0557 0.5072
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.001 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0557 0.096
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0377 0.0649
Toxoplasma gondii beta-tubulin, putative 0.0285 0.2825 1
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0028 0.0173 0.1478
Schistosoma mansoni hypothetical protein 0.089 0.9074 1
Loa Loa (eye worm) tubulin beta-2A chain 0.0285 0.2825 0.5558
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.0173 0.021
Trypanosoma brucei alpha tubulin, putative 0.0085 0.0761 0.2695
Loa Loa (eye worm) tubulin gamma chain 0.015 0.1435 0.2823
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0121 0.1129 0.2221
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0118 0.0204
Loa Loa (eye worm) hypothetical protein 0.0116 0.1083 0.2132
Toxoplasma gondii ABC1 family protein 0.0116 0.1083 0.3835
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0028 0.0173 0.0341
Trichomonas vaginalis tubulin alpha chain, putative 0.0085 0.0761 0.1312
Plasmodium falciparum thioredoxin reductase 0.011 0.1022 0.3618
Schistosoma mansoni ets-related 0.0242 0.2388 0.2632
Echinococcus multilocularis ewsr:fli fusion protein type 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0012 0.001 0.0017
Leishmania major ion transport protein-like protein 0.0013 0.0015 0.0054
Echinococcus granulosus ewsr:fli fusion protein type 0.0012 0.0003 0.0003
Schistosoma mansoni tubulin subunit beta 0.0285 0.2825 0.3113
Brugia malayi hypothetical protein 0.0034 0.0238 0.0468
Schistosoma mansoni ap endonuclease 0.0023 0.0118 0.013
Loa Loa (eye worm) hypothetical protein 0.0384 0.3852 0.7577
Schistosoma mansoni lamin 0.006 0.0507 0.0558
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.0278 0.0984
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0087 0.0308
Echinococcus multilocularis tubulin epsilon chain 0.015 0.1435 0.1435
Schistosoma mansoni tubulin subunit beta 0.0285 0.2825 0.3113
Mycobacterium tuberculosis Probable dehydrogenase 0.0251 0.2481 0.3272
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Schistosoma mansoni hypothetical protein 0.0324 0.3229 0.3559
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0063 0.0225
Trichomonas vaginalis DNA helicase recq, putative 0.0048 0.0377 0.0649
Loa Loa (eye worm) hypothetical protein 0.014 0.1333 0.2623
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.015 0.1435 0.508
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0123 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1997 0.3443
Trichomonas vaginalis tubulin epsilon chain, putative 0.0285 0.2825 0.4869
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0083 0.0164
Loa Loa (eye worm) hypothetical protein 0.0116 0.1083 0.2132
Echinococcus granulosus tubulin alpha 3 chain 0.0206 0.2007 0.2212
Echinococcus multilocularis tubulin subunit beta 0.0285 0.2825 0.2825
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0076 0.0131
Trypanosoma cruzi beta tubulin, putative 0.0285 0.2825 1
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0278 0.0984
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0013 0.0015 0.003
Mycobacterium tuberculosis Probable reductase 0.0251 0.2481 0.3272
Loa Loa (eye worm) hypothetical protein 0.0053 0.0433 0.0851
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0086 0.0771 0.1328
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Echinococcus multilocularis tubulin gamma 1 chain 0.015 0.1435 0.1435
Trichomonas vaginalis tubulin beta chain, putative 0.0206 0.2007 0.3459
Echinococcus multilocularis thioredoxin glutathione reductase 0.011 0.1022 0.1022
Trypanosoma cruzi alpha tubulin, putative 0.0206 0.2007 0.7104
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0072 0.0629 0.0629
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0279 0.277 0.3656
Trichomonas vaginalis tubulin beta chain, putative 0.0285 0.2825 0.4869
Plasmodium vivax hypothetical protein, conserved 0.0116 0.1083 0.3835
Echinococcus multilocularis tubulin alpha 1C chain 0.0206 0.2007 0.2007
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.0344 0.0379
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0083 0.0092
Leishmania major beta tubulin 0.0285 0.2825 1
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.1083 0.1868
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1997 0.3443
Giardia lamblia Gamma tubulin 0.015 0.1435 0.508
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0123 0.0136
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0223 0.0384
Brugia malayi Fli-1 protein 0.0242 0.2388 0.4698
Trichomonas vaginalis tubulin beta chain, putative 0.0206 0.2007 0.3459
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0217 0.0768
Schistosoma mansoni twik family of potassium channels-related 0.0013 0.0015 0.0017
Echinococcus granulosus beta tubulin 0.0285 0.2825 0.3113
Onchocerca volvulus 0.0013 0.0015 0.0009
Trichomonas vaginalis set domain proteins, putative 0.0573 0.5802 1
Echinococcus multilocularis small conductance calcium activated potassium 0.0324 0.3229 0.3229
Giardia lamblia Beta tubulin 0.0285 0.2825 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0147 0.052
Loa Loa (eye worm) BEN-1 protein 0.0285 0.2825 0.5558
Brugia malayi transcription factor E74 isoform 0.0012 0.0003 0.0006
Echinococcus multilocularis calcium activated potassium channel variant 0.0013 0.0015 0.0015
Echinococcus multilocularis lamin 0.006 0.0507 0.0507
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0116 0.1083 0.1418
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0083 0.0294
Loa Loa (eye worm) TWK-7 protein 0.0013 0.0015 0.003
Echinococcus granulosus GA binding protein alpha chain 0.008 0.0708 0.0781
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0012 0.001 0.0035
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0123 0.0123
Leishmania major epsilon tubulin, putative 0.015 0.1435 0.508
Brugia malayi Ets-domain containing protein 0.008 0.0708 0.1394
Loa Loa (eye worm) D-ets-2 protein 0.0012 0.0003 0.0006
Entamoeba histolytica tubulin alpha-1 chain 0.0206 0.2007 0.7104
Echinococcus multilocularis bloom syndrome protein 0.0048 0.0377 0.0377
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3105 0.5353
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0184 0.0203
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0012 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0251 0.2481 0.3272
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.1083 0.3835
Schistosoma mansoni tubulin subunit epsilon 0.015 0.1435 0.1581
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0028 0.0173 0.1478
Treponema pallidum NADH oxidase 0.0038 0.0278 0.3642
Echinococcus granulosus calcium activated potassium channel variant 0.0013 0.0015 0.0017
Trypanosoma cruzi polo-like protein kinase, putative 0.0086 0.0771 0.2728
Echinococcus multilocularis beta tubulin 0.0285 0.2825 0.2825
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Echinococcus multilocularis Tubulin alpha 1 chain 0.0206 0.2007 0.2007
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0123 0.0136
Trypanosoma brucei zeta tubulin, putative 0.0065 0.0557 0.1972
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0083 0.0083
Brugia malayi Bloom's syndrome protein homolog 0.0048 0.0377 0.0741
Leishmania major beta tubulin 0.0285 0.2825 1
Trypanosoma brucei glucosidase, putative 0.0033 0.0223 0.0789
Schistosoma mansoni hypothetical protein 0.089 0.9074 1
Echinococcus multilocularis ets variant gene 4 0.0012 0.0003 0.0003
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0087 0.0171
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0068 0.0587 0.5349
Entamoeba histolytica hypothetical protein 0.004 0.03 0.1061
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0116 0.1083 0.2132
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0083 0.0143
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.0173 0.021
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3105 0.5353
Loa Loa (eye worm) hypothetical protein 0.0028 0.0173 0.034
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0038 0.0278 0.0984
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0123 0.0212
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.014 0.1333 0.2298
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0063 0.007
Brugia malayi hypothetical protein 0.0169 0.1632 0.321
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0083 0.0294
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.001 0.0017
Echinococcus granulosus microtubule associated protein 2 0.071 0.722 0.7957
Echinococcus multilocularis peroxisome assembly protein 26 0.0206 0.2007 0.2007
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0021 0.0075
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.0344 0.0344
Plasmodium vivax tubulin epsilon chain, putative 0.015 0.1435 0.508
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Schistosoma mansoni alpha-glucosidase 0.0127 0.1201 0.1323
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0118 0.013
Trichomonas vaginalis sucrase-isomaltase, putative 0.0033 0.0223 0.0384
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1997 0.3443
Entamoeba histolytica hypothetical protein 0.0023 0.0123 0.0436
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Onchocerca volvulus 0.0013 0.0015 0.0009
Trypanosoma cruzi ion transport protein, putative 0.0013 0.0015 0.0054
Schistosoma mansoni intermediate filament proteins 0.006 0.0507 0.0558
Schistosoma mansoni DNA polymerase eta 0.0019 0.0083 0.0092
Schistosoma mansoni hypothetical protein 0.004 0.03 0.033
Echinococcus granulosus expressed protein 0.0452 0.4552 0.5017
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0013 0.0015 0.0054
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0147 0.0253
Entamoeba histolytica tubulin alpha chain, putative 0.0206 0.2007 0.7104
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0063 0.0225
Onchocerca volvulus 0.0013 0.0015 0.0009
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0038 0.0278 0.3642
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0087 0.0087
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0123 0.0136
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0012 0.001 0.0017
Trypanosoma brucei unspecified product 0.0013 0.0021 0.0075
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0038 0.0278 0.0984
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0123 0.0123
Echinococcus multilocularis lysosomal alpha glucosidase 0.0148 0.1414 0.1414
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0017 0.0019
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0285 0.2825 0.2825
Schistosoma mansoni tubulin subunit beta 0.0065 0.0557 0.0614
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0742 0.755 1
Schistosoma mansoni hypothetical protein 0.0012 0.0003 0.0003
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0118 0.0136
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0433 0.1532
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.0278 0.0984
Echinococcus multilocularis twik family of potassium channels 0.0013 0.0015 0.0015
Trichomonas vaginalis tubulin gamma chain, putative 0.015 0.1435 0.2474
Brugia malayi Cytochrome P450 family protein 0.0068 0.0587 0.1154
Schistosoma mansoni hypothetical protein 0.0024 0.013 0.0143
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0123 0.0136
Trichomonas vaginalis tubulin epsilon chain, putative 0.0065 0.0557 0.096
Trichomonas vaginalis tubulin beta chain, putative 0.0085 0.0761 0.1312
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.0173 0.021
Trypanosoma cruzi zeta tubulin, putative 0.0065 0.0557 0.1972
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0123 0.0212
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0013 0.0015 0.003
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0085 0.0761 0.1312
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0278 0.0984
Echinococcus granulosus histone lysine methyltransferase setb 0.0072 0.0629 0.0693
Schistosoma mansoni alpha tubulin 0.0206 0.2007 0.2212
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0038 0.0278 0.0306
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0013 0.0015 0.0054
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.0017 0.0017
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0012 0.0003 0.0006
Echinococcus granulosus tubulin alpha 1C chain 0.0206 0.2007 0.2212
Loa Loa (eye worm) hypothetical protein 0.0038 0.0277 0.0544
Loa Loa (eye worm) hypothetical protein 0.0116 0.1083 0.2132
Leishmania major beta tubulin 0.0285 0.2825 1
Echinococcus granulosus tubulin subunit TubB 0.0206 0.2007 0.2212
Leishmania major beta tubulin 0.0285 0.2825 1
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0013 0.0015 0.0017
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0013 0.0015 0.003
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0223 0.0384
Schistosoma mansoni lamin 0.006 0.0507 0.0558
Plasmodium vivax tubulin alpha chain, putative 0.0206 0.2007 0.7104
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0038 0.0278 0.0984
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0116 0.1083 0.1418
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0013 0.0015 0.003
Echinococcus granulosus survival motor neuron protein 1 0.0243 0.2398 0.2642
Trypanosoma cruzi epsilon tubulin, putative 0.015 0.1435 0.508
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Schistosoma mansoni alpha tubulin 0.0206 0.2007 0.2212
Brugia malayi Tubulin beta chain 0.0065 0.0557 0.1096
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0123 0.0242
Giardia lamblia Beta tubulin 0.0285 0.2825 1
Echinococcus granulosus tubulin alpha chain 0.0206 0.2007 0.2212
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0087 0.0096
Brugia malayi hypothetical protein 0.0023 0.0123 0.0242
Loa Loa (eye worm) tubulin beta-1 chain 0.0285 0.2825 0.5558
Schistosoma mansoni tubulin subunit beta 0.0285 0.2825 0.3113
Trichomonas vaginalis tubulin alpha chain, putative 0.0085 0.0761 0.1312
Trypanosoma brucei alpha tubulin 0.0206 0.2007 0.7104
Trichomonas vaginalis esterase, putative 0.0116 0.1083 0.1868
Brugia malayi hypothetical protein 0.0243 0.2398 0.4717
Mycobacterium tuberculosis Probable lipase LipE 0.0116 0.1083 0.1418
Leishmania major beta tubulin 0.0285 0.2825 1
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0013 0.0015 0.0054
Loa Loa (eye worm) tubulin beta chain 0.0285 0.2825 0.5558
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3105 0.5353
Brugia malayi hypothetical protein 0.0013 0.0015 0.003
Echinococcus granulosus thioredoxin glutathione reductase 0.011 0.1022 0.1126
Brugia malayi Pre-SET motif family protein 0.0503 0.5083 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.1244 0.2446
Leishmania major DNA polymerase eta, putative 0.0019 0.0083 0.0294
Leishmania major beta tubulin 0.0285 0.2825 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0086 0.0771 0.2728
Echinococcus granulosus twik family of potassium channels 0.0013 0.0015 0.0017
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0118 0.0232
Echinococcus multilocularis tubulin beta 1 chain 0.0285 0.2825 0.2825
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0087 0.0096
Echinococcus granulosus alpha tubulin 0.0206 0.2007 0.2212
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0028 0.0173 0.1478
Mycobacterium tuberculosis Probable oxidoreductase 0.0279 0.277 0.3656
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.0173 0.021
Brugia malayi hypothetical protein 0.0147 0.1406 0.2766
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0038 0.0278 0.0547
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0083 0.0294
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0006
Loa Loa (eye worm) tubulin alpha chain 0.0206 0.2007 0.3948
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0028 0.0173 0.1478
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0126 0.0139
Schistosoma mansoni DNA helicase recq5 0.002 0.0087 0.0096
Trichomonas vaginalis penicillin-binding protein, putative 0.0116 0.1083 0.1868
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0251 0.2481 0.8884
Mycobacterium leprae Probable lipase LipE 0.0116 0.1083 0.3505
Trichomonas vaginalis maltase-glucoamylase, putative 0.0012 0.001 0.0017
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0118 0.0962
Leishmania major glycosyl hydrolase-like protein 0.0012 0.001 0.0035
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Echinococcus granulosus tubulin gamma 1 chain 0.015 0.1435 0.1581
Echinococcus granulosus tubulin alpha 0.015 0.1435 0.1581
Schistosoma mansoni cytochrome P450 0.0028 0.0173 0.0191
Mycobacterium tuberculosis Conserved protein 0.0116 0.1083 0.1418
Trypanosoma brucei alpha tubulin 0.0206 0.2007 0.7104
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0012 0.001 0.0035
Echinococcus multilocularis tubulin alpha chain 0.0206 0.2007 0.2007
Toxoplasma gondii exonuclease III APE 0.0023 0.0118 0.0418
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0038 0.0278 0.0984
Giardia lamblia Alpha-tubulin 0.0206 0.2007 0.7104
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Onchocerca volvulus 0.0013 0.0015 0.0009
Trypanosoma brucei cytochrome P450, putative 0.0068 0.0587 0.2077
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.03 0.033
Echinococcus granulosus tubulin alpha chain 0.0206 0.2007 0.2212
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0028 0.0173 0.1478
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0173 0.0613
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0038 0.0278 0.0349
Echinococcus granulosus potassium channel subfamily K 8 0.0013 0.0015 0.0017
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.1083 0.1868
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0028 0.0173 0.0341
Leishmania major hypothetical protein, conserved 0.0116 0.1083 0.3835
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3105 0.5353
Brugia malayi hypothetical protein 0.0013 0.0015 0.003
Leishmania major calcium/potassium channel (CAKC), putative 0.0013 0.0015 0.0054
Brugia malayi Tubulin beta-1 chain 0.0285 0.2825 0.5558
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0123 0.0136
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0118 0.0418
Schistosoma mansoni calcium-activated potassium channel 0.0324 0.3229 0.3559
Loa Loa (eye worm) TWK-28 protein 0.0013 0.0015 0.003
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0038 0.0278 0.2459
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0083 0.0294
Schistosoma mansoni kinase 0.0044 0.0334 0.0368
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Loa Loa (eye worm) hypothetical protein 0.0039 0.0283 0.0556
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0126 0.0139
Echinococcus granulosus dna polymerase eta 0.0019 0.0083 0.0092
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0123 0.0136
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.002
Echinococcus multilocularis tubulin alpha chain 0.0206 0.2007 0.2007
Echinococcus multilocularis GA binding protein alpha chain 0.008 0.0708 0.0708
Trichomonas vaginalis tubulin beta chain, putative 0.0206 0.2007 0.3459
Entamoeba histolytica tubulin family protein 0.0285 0.2825 1
Plasmodium vivax delta tubulin, putative 0.0065 0.0557 0.1972
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0054 0.0445 0.0767
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0063 0.0225
Loa Loa (eye worm) acetyltransferase 0.0162 0.156 0.307
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0123 0.0242
Echinococcus granulosus tubulin alpha chain 0.0206 0.2007 0.2212
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0028 0.0173 0.1478
Echinococcus multilocularis potassium channel subfamily K 0.0013 0.0015 0.0015
Echinococcus multilocularis tubulin alpha 1C chain 0.0206 0.2007 0.2007
Loa Loa (eye worm) RecQ helicase 0.0048 0.0377 0.0741
Leishmania major trypanothione reductase 0.011 0.1022 0.3618
Schistosoma mansoni alpha glucosidase 0.0033 0.0223 0.0246
Brugia malayi Tubulin alpha chain 0.0065 0.0557 0.1096
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0433 0.1532
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0118 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0028 0.0173 0.1478
Trichomonas vaginalis tubulin, putative 0.0085 0.0761 0.1312
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0171
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Echinococcus multilocularis Tubulin beta 2C chain 0.0285 0.2825 0.2825
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0033 0.0223 0.0789
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0286 0.2838 0.5583
Brugia malayi Glycosyl hydrolases family 31 protein 0.0148 0.1414 0.2781
Leishmania major cytochrome p450-like protein 0.0028 0.0173 0.0613
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0173 0.0191
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0083 0.0083
Loa Loa (eye worm) tubulin beta chain 0.0065 0.0557 0.1096
Plasmodium vivax glutathione reductase, putative 0.011 0.1022 0.3618
Schistosoma mansoni calcium-activated potassium channel 0.0249 0.2457 0.2708
Onchocerca volvulus Serine\/threonine kinase homolog 0.0086 0.0771 0.1313
Echinococcus multilocularis Tubulin beta 2C chain 0.0285 0.2825 0.2825
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0123 0.0136
Mycobacterium tuberculosis Cell division protein FtsZ 0.0065 0.0557 0.0719
Onchocerca volvulus 0.0013 0.0015 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0015 0.0054
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0123 0.0212
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0336 0.1188
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0118 0.0418
Leishmania major beta tubulin 0.0285 0.2825 1
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0065 0.0557 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0377 0.0415
Trypanosoma brucei glycosyl hydrolase-like protein 0.0012 0.001 0.0035
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0162 0.156 0.172
Onchocerca volvulus 0.0013 0.0015 0.0009
Echinococcus multilocularis geminin 0.089 0.9074 0.9074
Loa Loa (eye worm) intermediate filament protein 0.006 0.0507 0.0997
Echinococcus multilocularis microtubule associated protein 2 0.071 0.722 0.722
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0223 0.0384
Schistosoma mansoni twik family of potassium channels-related 0.0013 0.0015 0.0017
Brugia malayi alpha-tubulin 0.0206 0.2007 0.3948
Echinococcus multilocularis ETS transcription factor Elf 5 0.0012 0.0003 0.0003
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0123 0.0242
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0013 0.0015 0.003
Giardia lamblia Hypothetical protein 0.0013 0.0015 0.0054
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0213 0.0754
Loa Loa (eye worm) hypothetical protein 0.0116 0.1083 0.2132
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0038 0.0278 0.3642
Trypanosoma brucei tubulin delta chain 0.0065 0.0557 0.1972
Trypanosoma brucei polo-like protein kinase 0.0086 0.0771 0.2728
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0771 0.0849
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0028 0.0173 0.1478
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0013 0.0015 0.003
Trichomonas vaginalis tubulin epsilon chain, putative 0.0206 0.2007 0.3459
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.3105 0.6109
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0118 0.0118
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0217 0.0427
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0017 0.0017
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.3105 0.6109
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0251 0.2481 0.3272
Mycobacterium tuberculosis Probable esterase LipL 0.0116 0.1083 0.1418
Brugia malayi Intermediate filament tail domain containing protein 0.006 0.0507 0.0997
Plasmodium vivax tubulin beta chain, putative 0.0285 0.2825 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0285 0.2825 0.2825
Mycobacterium tuberculosis Conserved protein 0.0116 0.1083 0.1418
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0336 0.1188
Toxoplasma gondii beta-1 tubulin, putative 0.0285 0.2825 1
Trichomonas vaginalis CAMK family protein kinase 0.0086 0.0771 0.1328
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0072 0.0629 0.0693
Leishmania major beta tubulin 0.0285 0.2825 1
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Echinococcus granulosus geminin 0.089 0.9074 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0121 0.1129 0.1946
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0087 0.0308
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0028 0.0173 0.1478
Leishmania major hypothetical protein, conserved 0.0013 0.0015 0.0054
Leishmania major beta tubulin 0.0285 0.2825 1
Schistosoma mansoni tubulin subunit beta 0.0285 0.2825 0.3113
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Onchocerca volvulus 0.0116 0.1083 0.1854
Echinococcus granulosus beta tubulin 0.0285 0.2825 0.3113
Brugia malayi MH2 domain containing protein 0.0132 0.1244 0.2446
Echinococcus multilocularis beta LACTamase domain containing family member 0.0116 0.1083 0.1083
Trypanosoma brucei beta tubulin 0.015 0.1435 0.508
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Brugia malayi beta-lactamase family protein 0.0116 0.1083 0.2132
Onchocerca volvulus 0.0086 0.0768 0.131
Loa Loa (eye worm) hypothetical protein 0.0169 0.1632 0.321
Giardia lamblia Beta tubulin 0.0285 0.2825 1
Giardia lamblia Delta tubulin 0.0065 0.0557 0.1972
Schistosoma mansoni twik family of potassium channels-related 0.0013 0.0015 0.0017
Loa Loa (eye worm) cytochrome P450 0.0028 0.0173 0.0341
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0038 0.0278 0.5
Echinococcus multilocularis beta tubulin 0.0285 0.2825 0.2825
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0557 0.096
Leishmania major hypothetical protein, conserved 0.0013 0.0015 0.0054
Echinococcus multilocularis protein C ets 2 0.0012 0.0003 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0223 0.0384
Trichomonas vaginalis glutathione reductase, putative 0.0038 0.0278 0.0479
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0433 0.1532
Brugia malayi isocitrate dehydrogenase 0.0017 0.0063 0.0125
Entamoeba histolytica hypothetical protein 0.004 0.03 0.1061
Onchocerca volvulus 0.005 0.0396 0.0667
Plasmodium vivax thioredoxin reductase, putative 0.011 0.1022 0.3618
Echinococcus multilocularis lamin dm0 0.006 0.0507 0.0507
Leishmania major hypothetical protein, conserved 0.0053 0.0433 0.1532
Trypanosoma cruzi zeta tubulin, putative 0.0065 0.0557 0.1972
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0083 0.0143
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0433 0.1532
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0072 0.0629 0.0693
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Brugia malayi hypothetical protein 0.0053 0.0433 0.0851
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0123 0.0136
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Echinococcus granulosus Tubulin beta 2C chain 0.0285 0.2825 0.3113
Leishmania major beta tubulin 0.0285 0.2825 1
Plasmodium falciparum glutathione reductase 0.011 0.1022 0.3618
Leishmania major zeta tubulin, putative 0.0065 0.0557 0.1972
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0063 0.0064
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0503 0.5083 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0123 0.0136
Echinococcus granulosus peroxisome assembly protein 26 0.0206 0.2007 0.2212
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0045 0.0344 0.0676
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0087 0.0308
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0028 0.0173 0.1478
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.03 0.03
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0038 0.0278 0.2459
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0126 0.0248
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.0173 0.021
Brugia malayi cytochrome P450 0.0028 0.0173 0.0341
Schistosoma mansoni tubulin subunit alpha 0.0206 0.2007 0.2212
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0116 0.1083 0.2132
Mycobacterium ulcerans beta-lactamase 0.0116 0.1083 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0278 0.0984
Loa Loa (eye worm) ets-domain-containing protein 0.0012 0.0003 0.0006
Schistosoma mansoni microtubule-associated protein tau 0.071 0.722 0.7957
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0123 0.0212
Echinococcus multilocularis ETS transcription factor Elf 1 0.0012 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0086 0.0771 0.1328
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0083 0.009
Echinococcus multilocularis tubulin delta chain 0.0065 0.0557 0.0557
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0013 0.0015 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0278 0.0984
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0278 0.0984
Echinococcus granulosus tubulin beta 4A class IVa 0.0285 0.2825 0.3113
Trypanosoma brucei epsilon tubulin 0.015 0.1435 0.508
Echinococcus multilocularis Tubulin alpha 1 chain 0.0206 0.2007 0.2007
Echinococcus multilocularis tubulin alpha chain 0.0206 0.2007 0.2007
Schistosoma mansoni hypothetical protein 0.0012 0.0003 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0017 0.0019
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0118 0.0418
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0003 0.0003
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0118 0.0418
Brugia malayi Cytochrome P450 family protein 0.0028 0.0173 0.0341
Trichomonas vaginalis CAMK family protein kinase 0.0043 0.0323 0.0556
Onchocerca volvulus 0.0116 0.1083 0.1854
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0063 0.0125
Leishmania major beta tubulin 0.0285 0.2825 1
Leishmania major beta tubulin 0.0285 0.2825 1
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0013 0.0015 0.0015
Plasmodium vivax tubulin alpha chain, putative 0.0206 0.2007 0.7104
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0123 0.0136
Brugia malayi DNA-binding protein D-ETS-3 0.0012 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0123 0.0242
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0033 0.0223 0.0439
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0045 0.0344 0.0676
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0118 0.0418
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0123 0.0136
Schistosoma mansoni elf1 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0206 0.2007 0.3948
Giardia lamblia NADH oxidase lateral transfer candidate 0.0038 0.0278 0.0984
Trichomonas vaginalis tubulin gamma chain, putative 0.0065 0.0557 0.096
Brugia malayi Tubulin alpha chain 0.0206 0.2007 0.3948
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0028 0.0173 0.1478
Schistosoma mansoni hypothetical protein 0.0013 0.0015 0.0017
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0377 0.1333
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0063 0.0225
Mycobacterium tuberculosis Probable hydrolase 0.0116 0.1083 0.1418
Trichomonas vaginalis tubulin alpha chain, putative 0.0285 0.2825 0.4869
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0123 0.0136
Trypanosoma cruzi ion transport protein, putative 0.0013 0.0015 0.0054
Brugia malayi PXA domain containing protein 0.0023 0.0123 0.0242
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0173 0.0613
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0251 0.2481 0.3272
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0123 0.0136
Leishmania major beta tubulin 0.0285 0.2825 1
Loa Loa (eye worm) beta-tubulin 0.0285 0.2825 0.5558
Brugia malayi Tubulin beta chain 0.0085 0.0761 0.1498
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0083 0.0635
Giardia lamblia Epsilon tubulin 0.0065 0.0557 0.1972
Echinococcus multilocularis Tubulin alpha 1 chain 0.0206 0.2007 0.2007
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3105 0.5353
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0086 0.0771 0.0771
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0396 0.078
Trichomonas vaginalis tubulin beta chain, putative 0.0206 0.2007 0.3459
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0063 0.0225
Echinococcus granulosus Tubulin beta 2C chain 0.0285 0.2825 0.3113
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0087 0.0171
Plasmodium vivax tubulin gamma chain, putative 0.015 0.1435 0.508
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0028 0.0173 0.1478
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0126 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1997 0.3443
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.011 0.1022 0.1336
Trypanosoma brucei tubulin gamma chain 0.015 0.1435 0.508
Trypanosoma brucei epsilon tubulin 0.015 0.1435 0.508
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0433 0.1532
Schistosoma mansoni tubulin subunit alpha 0.0206 0.2007 0.2212
Plasmodium falciparum tubulin beta chain 0.0285 0.2825 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0377 0.0649
Plasmodium falciparum tubulin epsilon chain, putative 0.015 0.1435 0.508
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0386 0.0425
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0013 0.0015 0.003
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0433 0.1532
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Schistosoma mansoni twik family of potassium channels-related 0.0013 0.0015 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Schistosoma mansoni DNA helicase recq1 0.002 0.0087 0.0096
Leishmania major cytochrome p450-like protein 0.0028 0.0173 0.0613
Leishmania major delta tubulin, putative 0.0065 0.0557 0.1972
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0123 0.0123
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0013 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0206 0.2007 0.3459
Trichomonas vaginalis mercuric reductase, putative 0.0038 0.0278 0.0479
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0063 0.0225
Schistosoma mansoni blooms syndrome DNA helicase 0.0038 0.0273 0.0301
Brugia malayi Cell division protein ftsZ 0.0065 0.0557 0.1096
Onchocerca volvulus 0.0085 0.0761 0.1297
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.008 0.0708 0.1394
Schistosoma mansoni transcription factor LCR-F1 0.004 0.03 0.033
Echinococcus granulosus small conductance calcium activated potassium 0.0324 0.3229 0.3559
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0013 0.0015 0.0054
Echinococcus granulosus intermediate filament protein 0.006 0.0507 0.0558
Plasmodium falciparum potassium channel 0.0013 0.0015 0.0054
Loa Loa (eye worm) hypothetical protein 0.0116 0.1083 0.2132
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0123 0.0242
Echinococcus granulosus ETS transcription factor Elf 5 0.0012 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.0173 0.021
Brugia malayi Ets-domain containing protein 0.0012 0.0003 0.0006
Echinococcus multilocularis hypothetical protein 0.0206 0.2007 0.2007
Trypanosoma brucei alpha tubulin 0.0206 0.2007 0.7104
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0147 0.052
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.007 0.0602 0.0663
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0023 0.0123 0.0436
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0072 0.0629 0.0693
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.013 0.013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Giardia lamblia DINP protein human, muc B family 0.0019 0.0083 0.0294
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0038 0.0278 0.0984
Trichomonas vaginalis CAMK family protein kinase 0.0043 0.0323 0.0556
Onchocerca volvulus 0.006 0.0507 0.0858
Plasmodium falciparum alpha tubulin 1 0.0206 0.2007 0.7104
Trichomonas vaginalis tubulin beta chain, putative 0.0206 0.2007 0.3459
Echinococcus granulosus Tubulin beta 2C chain 0.0285 0.2825 0.3113
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.0173 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0123 0.0212
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0147 0.052
Echinococcus granulosus bloom syndrome protein 0.0048 0.0377 0.0415
Brugia malayi tubulin alpha chain - mouse 0.0206 0.2007 0.3948
Trypanosoma cruzi tubulin gamma chain 0.015 0.1435 0.508
Trichomonas vaginalis tubulin gamma chain, putative 0.015 0.1435 0.2474
Entamoeba histolytica hypothetical protein 0.004 0.03 0.1061
Echinococcus granulosus lysosomal alpha glucosidase 0.0148 0.1414 0.1558
Toxoplasma gondii alpha-tubulin I, putative 0.0206 0.2007 0.7104
Schistosoma mansoni tubulin subunit beta 0.0285 0.2825 0.3113
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0083 0.009
Echinococcus granulosus neutral alpha glucosidase AB 0.0033 0.0223 0.0246
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.0173 0.021
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1997 0.3443
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0587 0.1154
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0013 0.0017 0.0033
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0123 0.0136
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0028 0.0173 0.1478
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0013 0.0015 0.003
Echinococcus multilocularis tubulin alpha chain 0.0206 0.2007 0.2007
Loa Loa (eye worm) fli-1 protein 0.0242 0.2388 0.4698
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0587 0.1154
Loa Loa (eye worm) alpha-tubulin 0.0206 0.2007 0.3948
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.0278 0.0984
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1997 0.3443
Giardia lamblia Alpha-tubulin 0.0206 0.2007 0.7104
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0028 0.0173 0.1478
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0013 0.0015 0.0054
Trypanosoma brucei beta tubulin 0.0285 0.2825 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0317 0.1121
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0021 0.0075
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0013 0.0015 0.003
Loa Loa (eye worm) tubulin alpha chain 0.0206 0.2007 0.3948
Trypanosoma brucei hypothetical protein, conserved 0.0116 0.1083 0.3835
Echinococcus granulosus protein C ets 2 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0123 0.0242
Loa Loa (eye worm) tubulin alpha 2 0.014 0.1333 0.2623
Toxoplasma gondii ion channel protein 0.0013 0.0015 0.0054
Echinococcus multilocularis musashi 0.006 0.0507 0.0507
Trypanosoma brucei trypanothione reductase 0.011 0.1022 0.3618
Loa Loa (eye worm) BEN-1 protein 0.0285 0.2825 0.5558
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0278 0.0984
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0147 0.052
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0063 0.0225
Echinococcus granulosus tubulin beta 1 chain 0.0285 0.2825 0.3113
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0116 0.1083 0.2132
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0013 0.0015 0.0054
Schistosoma mansoni calcium-activated potassium channel 0.0013 0.0015 0.0017
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0279 0.277 1
Trypanosoma brucei unspecified product 0.0019 0.0083 0.0294
Plasmodium vivax potassium channel, putative 0.0013 0.0015 0.0054
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Brugia malayi beta-lactamase family protein 0.0116 0.1083 0.2132
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.0173 0.021
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.0173 0.021
Trichomonas vaginalis CAMK family protein kinase 0.0086 0.0771 0.1328
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0377 0.1333
Brugia malayi hypothetical protein 0.004 0.03 0.059
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0173 0.0613
Schistosoma mansoni hypothetical protein 0.0028 0.0173 0.0191
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0013 0.0015 0.003
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0184 0.0184
Mycobacterium tuberculosis Probable lipase LipD 0.0116 0.1083 0.1418
Trichomonas vaginalis tubulin alpha chain, putative 0.015 0.1435 0.2474
Trypanosoma brucei alpha tubulin 0.0206 0.2007 0.7104
Mycobacterium leprae cell division protein FtsZ 0.0065 0.0557 0.1478
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Brugia malayi glutathione reductase 0.011 0.1022 0.2011
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0021 0.0075
Loa Loa (eye worm) hypothetical protein 0.0068 0.0589 0.1158
Loa Loa (eye worm) hypothetical protein 0.0243 0.2398 0.4717
Loa Loa (eye worm) alpha-tubulin isotype 2 0.014 0.1333 0.2623
Echinococcus granulosus tubulin alpha chain 0.0206 0.2007 0.2212
Loa Loa (eye worm) thioredoxin reductase 0.011 0.1022 0.2011
Leishmania major alpha glucosidase II subunit, putative 0.0033 0.0223 0.0789
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0217 0.0427
Toxoplasma gondii thioredoxin reductase 0.011 0.1022 0.3618
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0223 0.0789
Echinococcus multilocularis tubulin alpha 3 chain 0.0206 0.2007 0.2007
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0123 0.0212
Toxoplasma gondii alpha tubulin TUBA1 0.0206 0.2007 0.7104
Trichomonas vaginalis tubulin epsilon chain, putative 0.0206 0.2007 0.3459
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0087 0.0087
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0118 0.0418
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0433 0.1532
Loa Loa (eye worm) hypothetical protein 0.0013 0.0017 0.0033
Echinococcus granulosus Tubulin beta 2C chain 0.0285 0.2825 0.3113
Trypanosoma cruzi tubulin delta chain 0.0065 0.0557 0.1972
Brugia malayi follicle stimulating hormone receptor 0.0286 0.2838 0.5583
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0123 0.0242
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0063 0.0063
Echinococcus granulosus tubulin alpha 1C chain 0.0206 0.2007 0.2212
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0038 0.0278 0.0278
Trypanosoma brucei zeta tubulin 0.0065 0.0557 0.1972
Mycobacterium ulcerans esterase/lipase LipP 0.0116 0.1083 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.0173 0.021
Schistosoma mansoni tubulin subunit alpha 0.0206 0.2007 0.2212
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.0173 0.021
Loa Loa (eye worm) glutathione reductase 0.011 0.1022 0.2011
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0123 0.0123
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0065 0.0557 0.1972
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0123 0.0242
Brugia malayi tubulin alpha-2 chain 0.0206 0.2007 0.3948
Schistosoma mansoni ap endonuclease 0.0023 0.0118 0.013
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0063 0.0225
Echinococcus granulosus ETS domain containing protein Elk 1 0.0012 0.0003 0.0003
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0065 0.0557 0.096
Onchocerca volvulus 0.0013 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Trypanosoma brucei beta tubulin 0.0285 0.2825 1
Trypanosoma brucei beta tubulin 0.0285 0.2825 1
Echinococcus granulosus tubulin delta chain 0.0065 0.0557 0.0614
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0015 0.0054
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0173 0.0613
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0123 0.0136
Schistosoma mansoni twik family of potassium channels-related 0.0013 0.0015 0.0017
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0123 0.0123
Brugia malayi serine/threonine-protein kinase plk-2 0.0086 0.0771 0.1516
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.0173 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0123 0.0212
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0072 0.0629 0.2228
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0629 0.0693
Mycobacterium ulcerans hypothetical protein 0.0116 0.1083 1
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0028 0.0173 0.1478
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0083 0.0294
Loa Loa (eye worm) cytochrome P450 family protein 0.0071 0.0615 0.1209
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0063 0.0063
Trichomonas vaginalis tubulin, putative 0.0285 0.2825 0.4869
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0054 0.0445 0.0767
Loa Loa (eye worm) beta-lactamase 0.0116 0.1083 0.2132
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0033 0.0223 0.0384
Echinococcus multilocularis potassium channel subfamily K 8 0.0013 0.0015 0.0015
Schistosoma mansoni tubulin subunit gamma 0.015 0.1435 0.1581
Plasmodium vivax potassium channel, putative 0.0013 0.0015 0.0054
Brugia malayi beta-lactamase 0.0116 0.1083 0.2132
Entamoeba histolytica tubulin gamma chain 0.015 0.1435 0.508
Trichomonas vaginalis D-aminoacylase, putative 0.0116 0.1083 0.1868
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0386 0.0425
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0116 0.1083 0.1418
Loa Loa (eye worm) tubulin beta-4 chain 0.0285 0.2825 0.5558
Echinococcus granulosus ETS transcription factor Elf 1 0.0012 0.0003 0.0003
Loa Loa (eye worm) CYP4Cod1 0.0068 0.0587 0.1154
Plasmodium vivax SET domain protein, putative 0.0072 0.0629 0.2228
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0123 0.0136
Echinococcus multilocularis survival motor neuron protein 1 0.0243 0.2398 0.2398
Echinococcus granulosus histone acetyltransferase KAT2B 0.0158 0.1513 0.1668
Schistosoma mansoni ets 0.0012 0.0003 0.0003
Leishmania major beta tubulin 0.0285 0.2825 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0033 0.0223 0.0789
Trichomonas vaginalis tubulin gamma chain, putative 0.0285 0.2825 0.4869
Echinococcus granulosus dna polymerase kappa 0.0019 0.0083 0.0092
Trichomonas vaginalis tubulin beta chain, putative 0.0206 0.2007 0.3459
Trichomonas vaginalis tubulin epsilon chain, putative 0.0285 0.2825 0.4869
Leishmania major beta tubulin 0.0285 0.2825 1
Trypanosoma cruzi cytochrome P450, putative 0.0068 0.0587 0.2077
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.2111 0.3639
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.0173 0.021
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0083 0.0635
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0006
Schistosoma mansoni alpha-glucosidase 0.0127 0.1201 0.1323
Schistosoma mansoni survival motor neuron protein 0.005 0.0396 0.0437
Entamoeba histolytica hypothetical protein 0.0023 0.0123 0.0436
Brugia malayi hypothetical protein 0.0023 0.0123 0.0242
Toxoplasma gondii beta tubulin 0.0285 0.2825 1
Schistosoma mansoni hypothetical protein 0.005 0.0396 0.0437
Trypanosoma cruzi cytochrome P450, putative 0.0068 0.0587 0.2077
Entamoeba histolytica serine/threonine protein kinase, putative 0.0086 0.0771 0.2728
Plasmodium falciparum tubulin gamma chain 0.015 0.1435 0.508
Echinococcus granulosus lamin dm0 0.006 0.0507 0.0558
Schistosoma mansoni tubulin subunit delta 0.0065 0.0557 0.0614
Echinococcus multilocularis 0.0028 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Loa Loa (eye worm) hypothetical protein 0.0059 0.0495 0.0974
Brugia malayi Tubulin alpha-2 chain 0.0206 0.2007 0.3948
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0116 0.1083 1
Plasmodium falciparum alpha tubulin 2 0.0206 0.2007 0.7104
Schistosoma mansoni tubulin subunit alpha 0.0065 0.0557 0.0614
Leishmania major DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Echinococcus granulosus tubulin epsilon chain 0.015 0.1435 0.1581
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0013 0.0015 0.0015
Treponema pallidum cell division protein FtsZ 0.0065 0.0557 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0148 0.1414 0.2781
Mycobacterium tuberculosis Conserved protein 0.0116 0.1083 0.1418
Brugia malayi Glycosyl hydrolases family 31 protein 0.0033 0.0223 0.0439
Echinococcus multilocularis potassium channel subfamily K 8 0.0013 0.0015 0.0015
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0126 0.0248
Schistosoma mansoni twik family of potassium channels-related 0.0013 0.0015 0.0017
Trichomonas vaginalis tubulin alpha chain, putative 0.0085 0.0761 0.1312
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0013 0.0015 0.003
Trypanosoma brucei unspecified product 0.0013 0.0021 0.0075
Echinococcus granulosus potassium channel subfamily K 0.0013 0.0015 0.0017
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0013 0.0015 0.003
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0087 0.0171
Entamoeba histolytica hypothetical protein 0.004 0.03 0.1061
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.006 0.0507 0.0997
Trichomonas vaginalis alpha-glucosidase, putative 0.0033 0.0223 0.0384
Loa Loa (eye worm) alpha-tubulin 0.0206 0.2007 0.3948
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0013 0.0015 0.003
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0017 0.0019
Echinococcus granulosus lamin 0.006 0.0507 0.0558
Echinococcus multilocularis Tubulin beta 2C chain 0.0285 0.2825 0.2825
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3105 0.5353
Brugia malayi Glycosyl hydrolases family 31 protein 0.0012 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0131 0.124 0.2439
Leishmania major gamma-tubulin 0.015 0.1435 0.508
Echinococcus multilocularis twik family of potassium channels 0.0013 0.0015 0.0015
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0118 0.0418
Echinococcus granulosus Tubulin alpha 1 chain 0.0206 0.2007 0.2212
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0336 0.1188
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0083 0.0294
Trypanosoma brucei epsilon tubulin 0.015 0.1435 0.508
Echinococcus granulosus potassium channel subfamily K 8 0.0013 0.0015 0.0017
Echinococcus multilocularis Tubulin beta 2C chain 0.0285 0.2825 0.2825
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.0173 0.021
Loa Loa (eye worm) hypothetical protein 0.0062 0.0524 0.1031
Schistosoma mansoni twik family of potassium channels-related 0.0013 0.0015 0.0017
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0063 0.0225
Echinococcus granulosus tubulin alpha chain 0.0206 0.2007 0.2212
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0028 0.0173 0.1478
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0123 0.0123
Echinococcus multilocularis lysosomal alpha glucosidase 0.0148 0.1414 0.1414
Leishmania major potassium channel subunit-like protein 0.0013 0.0015 0.0054
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0028 0.0173 0.1478
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.1244 0.2446
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.1997 0.3432
Leishmania major beta tubulin 0.0285 0.2825 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0086 0.0771 0.0849
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.013 0.0143
Brugia malayi Cytochrome P450 family protein 0.0068 0.0587 0.1154
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0012 0.001 0.0035
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0123 0.0123
Onchocerca volvulus 0.006 0.0507 0.0858
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0013 0.0015 0.0026
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Leishmania major beta tubulin 0.0285 0.2825 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0206 0.2007 0.2212
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0076 0.0131
Loa Loa (eye worm) tubulin alpha 2 0.014 0.1333 0.2623
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0013 0.0015 0.003
Schistosoma mansoni alpha tubulin 0.0206 0.2007 0.2212
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0013 0.0015 0.003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.0278 0.0984
Mycobacterium leprae conserved hypothetical protein 0.0116 0.1083 0.3505
Trypanosoma brucei beta tubulin 0.0285 0.2825 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0507 0.0997
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0118 0.0204
Loa Loa (eye worm) hypothetical protein 0.0118 0.1101 0.2165
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0083 0.0092
Echinococcus granulosus tubulin alpha 3 chain 0.0206 0.2007 0.2212
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.0173 0.021
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0013 0.0015 0.003
Trypanosoma brucei calcium-activated potassium channel, putative 0.0013 0.0015 0.0054
Brugia malayi intermediate filament protein 0.006 0.0507 0.0997
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0003 0.0003
Trichomonas vaginalis maltase-glucoamylase, putative 0.0033 0.0223 0.0384
Loa Loa (eye worm) hypothetical protein 0.004 0.0297 0.0584
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0065 0.0557 0.1972
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.1083 0.3835
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0126 0.0126
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0162 0.156 0.156
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0086 0.0771 0.1516
Schistosoma mansoni gabp alpha 0.008 0.0708 0.0781
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0013 0.0015 0.003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0083 0.0164
Echinococcus multilocularis neutral alpha glucosidase AB 0.0033 0.0223 0.0223
Onchocerca volvulus 0.0573 0.5802 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.0173 0.021
Brugia malayi PXA domain containing protein 0.0023 0.0123 0.0242
Trichomonas vaginalis CAMK family protein kinase 0.0086 0.0771 0.1328
Brugia malayi Thioredoxin reductase 0.011 0.1022 0.2011
Loa Loa (eye worm) tubulin alpha-2 chain 0.0206 0.2007 0.3948
Plasmodium falciparum tubulin delta chain, putative 0.0065 0.0557 0.1972
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0063 0.0063
Leishmania major cytochrome p450-like protein 0.0068 0.0587 0.2077
Schistosoma mansoni calcium-activated potassium channel 0.0013 0.0015 0.0017
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0038 0.0278 0.2459
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0028 0.0173 0.1478
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0123 0.0242
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0038 0.0278 0.0984
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0116 0.1083 0.1194
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0083 0.0164
Giardia lamblia Kinase, PLK 0.0086 0.0771 0.2728
Leishmania major beta tubulin 0.0285 0.2825 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0083 0.0164
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0116 0.1083 0.1194
Loa Loa (eye worm) hypothetical protein 0.0072 0.0629 0.1238
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0173 0.0613
Trypanosoma cruzi epsilon tubulin, putative 0.015 0.1435 0.508
Trichomonas vaginalis CAMK family protein kinase 0.0086 0.0771 0.1328
Echinococcus granulosus Tubulin alpha 1 chain 0.0206 0.2007 0.2212
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0087 0.0308
Echinococcus multilocularis tubulin alpha 3 chain 0.0206 0.2007 0.2007
Brugia malayi Tubulin alpha-2 chain 0.0206 0.2007 0.3948
Toxoplasma gondii ion channel protein 0.0013 0.0015 0.0054
Echinococcus granulosus voltage gated potassium channel 0.0013 0.0017 0.0019
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0028 0.0173 0.1478
Loa Loa (eye worm) tubulin alpha 2 0.0055 0.0455 0.0896
Echinococcus multilocularis tubulin alpha chain 0.0206 0.2007 0.2007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.003
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0279 0.277 0.3656
Loa Loa (eye worm) hypothetical protein 0.0028 0.0173 0.034
Leishmania major alpha tubulin 0.0206 0.2007 0.7104
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0278 0.0984
Echinococcus granulosus twik family of potassium channels 0.0013 0.0015 0.0017
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0033 0.0223 0.0789
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0173 0.0613
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.001 0.0017
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0324 0.3229 0.6353
Loa Loa (eye worm) hypothetical protein 0.0023 0.0123 0.0242
Echinococcus multilocularis tubulin alpha 0.015 0.1435 0.1435
Loa Loa (eye worm) uncoordinated protein 58 0.0013 0.0015 0.003

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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