Detailed information for compound 231691

Basic information

Technical information
  • TDR Targets ID: 231691
  • Name: 1-cyclopropyl-7-[(2R,3S)-3-(dimethylamino)-2- methylazetidin-1-yl]-6,8-difluoro-4-oxoquinol ine-3-carboxylic acid
  • MW: 377.385 | Formula: C19H21F2N3O3
  • H donors: 1 H acceptors: 3 LogP: 0.89 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN([C@H]1CN([C@@H]1C)c1c(F)cc2c(c1F)n(cc(c2=O)C(=O)O)C1CC1)C
  • InChi: 1S/C19H21F2N3O3/c1-9-14(22(2)3)8-23(9)17-13(20)6-11-16(15(17)21)24(10-4-5-10)7-12(18(11)25)19(26)27/h6-7,9-10,14H,4-5,8H2,1-3H3,(H,26,27)/t9-,14+/m1/s1
  • InChiKey: NZRIDVDCUMGXBN-OTYXRUKQSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-cyclopropyl-7-[(2R,3S)-3-(dimethylamino)-2-methyl-azetidin-1-yl]-6,8-difluoro-4-oxo-quinoline-3-carboxylic acid
  • 1-cyclopropyl-7-[(2R,3S)-3-(dimethylamino)-2-methyl-1-azetidinyl]-6,8-difluoro-4-oxo-3-quinolinecarboxylic acid
  • 1-cyclopropyl-7-[(2R,3S)-3-(dimethylamino)-2-methyl-azetidin-1-yl]-6,8-difluoro-4-keto-quinoline-3-carboxylic acid
  • 1-cyclopropyl-7-[(2R,3S)-3-dimethylamino-2-methylazetidin-1-yl]-6,8-difluoro-4-oxoquinoline-3-carboxylic acid
  • 1-cyclopropyl-7-[(2R,3S)-3-dimethylamino-2-methyl-azetidin-1-yl]-6,8-difluoro-4-oxo-quinoline-3-carboxylic acid
  • 1-cyclopropyl-7-[(2R,3S)-3-dimethylamino-2-methyl-1-azetidinyl]-6,8-difluoro-4-oxo-3-quinolinecarboxylic acid
  • 1-cyclopropyl-7-[(2R,3S)-3-dimethylamino-2-methyl-azetidin-1-yl]-6,8-difluoro-4-keto-quinoline-3-carboxylic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0019 0.0005 0.0004
Brugia malayi G protein-coupled receptor F59B2.13 0.0031 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Onchocerca volvulus 0.0039 0.0102 0.0195
Trypanosoma cruzi extracellular receptor, putative 0.0119 0.0489 0.0936
Echinococcus multilocularis neuropeptide receptor 0.0243 0.1095 0.1133
Schistosoma mansoni glutamate receptor NMDA 0.1996 0.966 0.966
Echinococcus granulosus casein kinase I alpha 0.0024 0.0027 0.0028
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0052 0.0163 0.0311
Mycobacterium leprae Probable two-component sensor kinase 0.0041 0.0107 0.0206
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.005 0.0155 0.0294
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0432 0.0587
Schistosoma mansoni signal transduction protein lnk-related 0.0029 0.0049 0.0047
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0031 0.0061 0.0063
Echinococcus multilocularis two pore calcium channel protein 2 0.0072 0.026 0.0269
Mycobacterium ulcerans pyruvate carboxylase 0.0053 0.0169 0.0228
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0092 0.0124
Mycobacterium ulcerans thymidylate synthase 0.1088 0.5224 0.7123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0145 0.0595
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0029 0.0049 0.0051
Trichomonas vaginalis tubulin alpha chain, putative 0.0025 0.0033 0.0137
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0031 0.0061 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0092 0.0177
Brugia malayi hypoxia-induced factor 1 0.0221 0.0989 0.1886
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.0016 0.003
Trypanosoma brucei heat shock protein 90, putative 0.0041 0.0107 0.0203
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0072 0.026 0.0497
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0072 0.026 0.0269
Echinococcus multilocularis hyperpolarization activated cyclic 0.0077 0.0288 0.0298
Brugia malayi Metabotropic glutamate receptor precursor. 0.0119 0.0489 0.0928
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0175 0.0331
Brugia malayi hypothetical protein 0.0039 0.0102 0.0186
Onchocerca volvulus 0.0029 0.0049 0.0094
Brugia malayi hypothetical protein 0.0042 0.0117 0.0215
Echinococcus granulosus glutamate receptor 2 0.0696 0.3312 0.3429
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0052 0.0068
Leishmania major zeta tubulin, putative 0.0019 0.0005 0.0009
Echinococcus granulosus geminin 0.0545 0.2573 0.2663
Echinococcus multilocularis transient receptor potential cation channel 0.0072 0.026 0.0269
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0061 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0162 0.0663
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.007
Schistosoma mansoni transient receptor potential channel 0.0072 0.026 0.0258
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0041 0.0107 0.0144
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0139 0.0265
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0092 0.0361 0.049
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0072 0.026 0.0489
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0065 0.0226 0.0234
Echinococcus multilocularis neuropeptide FF receptor 2 0.0031 0.0061 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0045 0.0186
Toxoplasma gondii Erv1 / Alr family protein 0.0026 0.0035 0.0045
Brugia malayi Immunoglobulin I-set domain containing protein 0.007 0.0253 0.0477
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.1082 0.5197 0.538
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.006 0.0114
Echinococcus multilocularis nmda type glutamate receptor 0.1487 0.7177 0.7429
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0087
Echinococcus multilocularis casein kinase I alpha 0.0024 0.0027 0.0028
Brugia malayi acetyltransferase, GNAT family protein 0.0163 0.0703 0.1339
Trichomonas vaginalis tubulin alpha chain, putative 0.0025 0.0033 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0081 0.033
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0029 0.0049 0.0051
Echinococcus multilocularis receptor type guanylyl cyclase 0.0129 0.0542 0.0561
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0026 0.0035 0.0041
Schistosoma mansoni hypothetical protein 0.0029 0.0049 0.0047
Onchocerca volvulus 0.0025 0.0033 0.0064
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0052 0.0068
Onchocerca volvulus 0.0047 0.0141 0.027
Echinococcus granulosus neuropeptide receptor A26 0.0031 0.0061 0.0063
Schistosoma mansoni intermediate filament proteins 0.0057 0.019 0.0188
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0072 0.026 0.0269
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0052 0.0068
Echinococcus granulosus potassium voltage gated channel protein 0.0072 0.026 0.0269
Mycobacterium tuberculosis Hypothetical protein 0.0517 0.2438 0.3323
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0092 0.0379
Toxoplasma gondii alpha-tubulin I, putative 0.0083 0.0317 0.043
Toxoplasma gondii hypothetical protein 0.0072 0.026 0.0352
Echinococcus multilocularis thymidylate synthase 0.1088 0.5224 0.5408
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0072 0.026 0.0258
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0072 0.026 0.0269
Trichomonas vaginalis CK1 family protein kinase 0.0024 0.0027 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Brugia malayi isocitrate dehydrogenase 0.0031 0.0061 0.0109
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0021 0.001 0.002
Schistosoma mansoni hypothetical protein 0.0042 0.0116 0.0115
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0031 0.006 0.0114
Schistosoma mansoni hypothetical protein 0.0027 0.0042 0.004
Echinococcus multilocularis glutamate receptor 2 0.0696 0.3312 0.3429
Echinococcus granulosus hyperpolarization activated cyclic 0.0077 0.0288 0.0298
Schistosoma mansoni histamine h1 receptor 0.0031 0.0061 0.006
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0053 0.0169 0.0228
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0092 0.0361 0.1479
Loa Loa (eye worm) SH2 domain-containing protein 0.0029 0.0049 0.0094
Loa Loa (eye worm) prolyl oligopeptidase 0.015 0.0641 0.1226
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0175 0.0331
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0031 0.0061 0.006
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0052 0.0064
Echinococcus multilocularis tubulin subunit TubB 0.0083 0.0317 0.0328
Leishmania major extracellular receptor, putative 0.0119 0.0489 0.0936
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Loa Loa (eye worm) RGC/RGC protein kinase 0.0129 0.0542 0.1037
Mycobacterium ulcerans putative regulatory protein 0.0053 0.0168 0.0226
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Schistosoma mansoni amine GPCR 0.0031 0.0061 0.006
Echinococcus granulosus lamin dm0 0.0057 0.019 0.0196
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0061 0.0063
Loa Loa (eye worm) TAR-binding protein 0.0038 0.0093 0.0178
Echinococcus multilocularis short transient receptor potential channel 6 0.0076 0.028 0.0289
Echinococcus multilocularis protein patched 0.0028 0.0047 0.0049
Onchocerca volvulus 0.004 0.0105 0.0201
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0061 0.0063
Onchocerca volvulus 0.0031 0.0061 0.0117
Trypanosoma cruzi DNA topoisomerase II, putative 0.037 0.1717 0.3287
Plasmodium falciparum thioredoxin reductase 0.0047 0.0139 0.0183
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0078 0.0292 0.0392
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0041 0.0107 0.0206
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0045 0.0046
Echinococcus granulosus tyrosine protein kinase Srms 0.0039 0.0102 0.0105
Brugia malayi Myosin tail family protein 0.0028 0.0045 0.0078
Echinococcus granulosus SH2 domain containing adapter protein F 0.0029 0.0049 0.0051
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0119 0.0489 0.0506
Schistosoma mansoni tubulin subunit gamma 0.0045 0.0129 0.0127
Plasmodium vivax tubulin gamma chain, putative 0.0045 0.0129 0.0169
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0031 0.006 0.0114
Echinococcus granulosus glutamate receptor subunit protein glur 0.0386 0.1794 0.1857
Trypanosoma brucei alpha tubulin 0.0083 0.0317 0.0603
Schistosoma mansoni sorbin 0.0028 0.0045 0.0044
Schistosoma mansoni growth factor receptor-bound protein 0.0056 0.0185 0.0184
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Onchocerca volvulus 0.0031 0.0061 0.0117
Onchocerca volvulus 0.006 0.0201 0.0384
Echinococcus granulosus tubulin subunit TubB 0.0083 0.0317 0.0328
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0061 0.006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0239 0.1079 0.147
Schistosoma mansoni tyrosine kinase 0.0129 0.0542 0.054
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0053 0.0169 0.0175
Schistosoma mansoni amine GPCR 0.0031 0.0061 0.006
Echinococcus granulosus src region 0.0028 0.0045 0.0047
Schistosoma mansoni tubulin subunit beta 0.0045 0.0129 0.0127
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0031 0.0059 0.011
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0067 0.0238 0.0246
Echinococcus multilocularis endophilin A3 0.0028 0.0045 0.0047
Loa Loa (eye worm) acetyltransferase 0.0163 0.0703 0.1346
Echinococcus granulosus N chimaerin 0.0029 0.0049 0.0051
Schistosoma mansoni amine GPCR 0.0031 0.0061 0.006
Brugia malayi SH2 domain containing protein 0.0029 0.0049 0.0085
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0092 0.0124
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Echinococcus multilocularis potassium voltage gated channel protein 0.0072 0.026 0.0269
Brugia malayi hypothetical protein 0.0288 0.1315 0.2511
Brugia malayi cation channel family protein 0.0072 0.026 0.0489
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.0288 0.0286
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0436 0.0452
Trichomonas vaginalis DNA topoisomerase II, putative 0.0462 0.2169 0.8896
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0583 0.0793
Trichomonas vaginalis tubulin epsilon chain, putative 0.0083 0.0317 0.1299
Echinococcus granulosus Tubulin alpha 1 chain 0.0083 0.0317 0.0328
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0053 0.0169 0.0323
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0063 0.0215 0.0404
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0052 0.0212
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0462 0.2169 0.4151
Schistosoma mansoni calcium-activated potassium channel 0.0072 0.026 0.0258
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0432 0.0827
Echinococcus multilocularis voltage dependent calcium channel 0.0072 0.026 0.0269
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0052 0.0212
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0053 0.0169 0.0228
Schistosoma mansoni adenoreceptor 0.0031 0.0061 0.006
Echinococcus granulosus hypothetical protein 0.0031 0.0061 0.0063
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0022 0.0016 0.0014
Echinococcus granulosus tyrosine kinase 0.0129 0.0542 0.0561
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.015 0.0641 0.0639
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0061 0.0063
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0072 0.026 0.0269
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Giardia lamblia Dipeptidyl-peptidase I precursor 0.003 0.0055 0.0255
Loa Loa (eye worm) tubulin alpha 2 0.0064 0.0221 0.0424
Echinococcus granulosus casein kinase I gamma 0.0037 0.009 0.0093
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.0308 0.0306
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0072 0.026 0.0489
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0028 0.0045 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0092 0.012
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0072 0.026 0.0489
Schistosoma mansoni terminal deoxycytidyl transferase 0.0026 0.0035 0.0034
Toxoplasma gondii heat shock protein HSP90 0.0041 0.0107 0.0144
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0031 0.006 0.0111
Loa Loa (eye worm) TK protein kinase 0.0039 0.0102 0.0195
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0031 0.0061 0.0108
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0105 0.0137
Schistosoma mansoni suppressor of cytokine signaling 0.0029 0.0049 0.0047
Schistosoma mansoni tyrosine kinase 0.0067 0.0238 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0076 0.0279 0.0278
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0061 0.006
Onchocerca volvulus 0.0031 0.0061 0.0117
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0026 0.0035 0.0041
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0019 0.0002 0.0003
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0041 0.0107 0.0144
Loa Loa (eye worm) hypothetical protein 0.0083 0.0317 0.0606
Loa Loa (eye worm) RNA binding protein 0.0038 0.0093 0.0178
Echinococcus granulosus metabotropic glutamate receptor 5 0.0119 0.0489 0.0506
Schistosoma mansoni jun-related protein 0.0049 0.0149 0.0147
Schistosoma mansoni pyruvate carboxylase 0.0053 0.0169 0.0167
Echinococcus granulosus dna polymerase kappa 0.0054 0.0175 0.0181
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0092 0.0096
Schistosoma mansoni biogenic amine receptor 0.0031 0.0061 0.006
Echinococcus multilocularis heat shock protein 90 0.0041 0.0107 0.0111
Brugia malayi bZIP transcription factor family protein 0.006 0.0204 0.0383
Echinococcus granulosus neuropeptide receptor 0.0243 0.1095 0.1133
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.009 0.0089
Mycobacterium ulcerans two component regulator - sensor kinase 0.0041 0.0107 0.0144
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0105 0.0109
Brugia malayi alpha-tubulin 0.0083 0.0317 0.0598
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0092 0.0361 0.1479
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0078 0.0292 0.1463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Schistosoma mansoni metabotropic glutamate receptor 0.0119 0.0489 0.0488
Trypanosoma cruzi aurora B kinase, putative 0.0132 0.0553 0.1058
Echinococcus granulosus tubulin alpha 1C chain 0.0083 0.0317 0.0328
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0174 0.0762 0.0789
Brugia malayi voltage-dependent calcium channel 0.0072 0.026 0.0489
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0163 0.0703 0.0702
Onchocerca volvulus 0.0028 0.0045 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0175 0.0331
Echinococcus multilocularis tyrosine protein kinase Blk 0.0039 0.0102 0.0105
Plasmodium vivax DNA topoisomerase 3, putative 0.0092 0.0361 0.0486
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0101 0.0402 0.0542
Toxoplasma gondii alpha tubulin TUBA1 0.0083 0.0317 0.043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0145 0.0595
Echinococcus granulosus dna polymerase eta 0.0039 0.0101 0.0105
Echinococcus granulosus lamin 0.0057 0.019 0.0196
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0041 0.0107 0.0144
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0201 0.0272
Brugia malayi Endoplasmin precursor 0.0041 0.0107 0.0197
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0061 0.0117
Plasmodium vivax DNA topoisomerase II, putative 0.0462 0.2169 0.2953
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0083 0.0317 0.1299
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0028 0.0045 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Leishmania major DNA topoisomerase ii 0.037 0.1717 0.3287
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0072 0.026 0.0258
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0092 0.0379
Schistosoma mansoni hypothetical protein 0.0029 0.0049 0.0047
Loa Loa (eye worm) hypoxia-induced factor 1 0.0221 0.0989 0.1893
Loa Loa (eye worm) beta-lactamase 0.0037 0.0092 0.0177
Schistosoma mansoni integrin alpha-4 0.0088 0.0337 0.0335
Toxoplasma gondii cathepsin CPC1 0.0078 0.0292 0.0396
Schistosoma mansoni tyrosine kinase 0.0043 0.0122 0.012
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.003 0.0055 0.0068
Onchocerca volvulus 0.0039 0.0102 0.0195
Loa Loa (eye worm) tubulin gamma chain 0.0045 0.0129 0.0246
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0028 0.0045 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0099 0.0405
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0061 0.006
Echinococcus granulosus integrin alpha ps 0.002 0.0009 0.001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0288 0.1181
Schistosoma mansoni two-pore calcium channel 0.0072 0.026 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.2438 1
Schistosoma mansoni suppressor of cytokine signaling 0.0029 0.0049 0.0047
Echinococcus granulosus tar DNA binding protein 0.0038 0.0093 0.0096
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0462 0.2169 0.4146
Schistosoma mansoni heat shock protein 0.0041 0.0107 0.0106
Brugia malayi putative neuropeptide receptor 0.0031 0.0061 0.0108
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0059 0.0198 0.0268
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0053 0.0169 0.0323
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0092 0.0177
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0175 0.0331
Echinococcus granulosus fmrfamide receptor 0.0031 0.0061 0.0063
Trichomonas vaginalis tubulin epsilon chain, putative 0.0045 0.0129 0.0527
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0152
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0072 0.026 0.0269
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0058 0.0193 0.079
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0436 0.0435
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Onchocerca volvulus 0.0477 0.2242 0.4292
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0022 0.0016 0.0027
Echinococcus granulosus tubulin beta 4A class IVa 0.0045 0.0129 0.0133
Onchocerca volvulus 0.0053 0.0168 0.0321
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0021 0.0014 0.0017
Schistosoma mansoni glutamate receptor kainate 0.0964 0.4617 0.4616
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0045 0.0078
Trypanosoma brucei beta tubulin 0.0045 0.0129 0.0243
Trypanosoma brucei beta tubulin 0.0045 0.0129 0.0243
Loa Loa (eye worm) hypothetical protein 0.0119 0.0489 0.0936
Entamoeba histolytica protein kinase, putative 0.0132 0.0553 0.246
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Loa Loa (eye worm) RGC/RGC protein kinase 0.0129 0.0542 0.1037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0029 0.0038
Brugia malayi Pre-SET motif family protein 0.0416 0.1941 0.3711
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0064 0.0221 0.0908
Trichomonas vaginalis AGC family protein kinase 0.0132 0.0553 0.2267
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Trypanosoma brucei epsilon tubulin 0.0045 0.0129 0.0243
Loa Loa (eye worm) hypothetical protein 0.0057 0.019 0.0363
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0436 0.0835
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0175 0.0334
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.0139 0.059 0.0802
Loa Loa (eye worm) glutathione reductase 0.0047 0.0139 0.0265
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.1088 0.5224 0.7123
Schistosoma mansoni hypothetical protein 0.0121 0.0499 0.0497
Schistosoma mansoni rab6-interacting 0.004 0.0105 0.0104
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0079 0.0143
Loa Loa (eye worm) tubulin beta-2A chain 0.0045 0.0129 0.0246
Trypanosoma cruzi heat shock protein 90, putative 0.0041 0.0107 0.0206
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Brugia malayi serine/threonine-protein kinase 6 0.0132 0.0553 0.105
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0119 0.0489 0.0665
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.0139 0.059 0.0802
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0024 0.0027 0.0052
Echinococcus granulosus tubulin gamma 1 chain 0.0045 0.0129 0.0133
Echinococcus granulosus mitogen activated protein kinase 14 0.0052 0.0163 0.0168
Trypanosoma brucei heat shock protein, putative 0.0041 0.0107 0.0203
Brugia malayi Cyclic-nucleotide gated cation channel 0.0077 0.0288 0.0543
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.006 0.0245
Leishmania major epsilon tubulin, putative 0.0045 0.0129 0.0246
Schistosoma mansoni lipoxygenase 0.0102 0.0409 0.0408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0016 0.0064
Brugia malayi protein-tyrosine kinase 0.0028 0.0045 0.0078
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0072 0.026 0.0489
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1289 0.5287
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Brugia malayi hypothetical protein 0.004 0.0105 0.0193
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0119 0.0489 0.0936
Toxoplasma gondii Erv1 / Alr family protein 0.0026 0.0035 0.0045
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0139 0.0187
Echinococcus granulosus two pore calcium channel protein 1 0.0072 0.026 0.0269
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.015 0.0641 0.0663
Echinococcus granulosus neuropeptide FF receptor 2 0.0031 0.0061 0.0063
Brugia malayi Tachykinin-like peptides receptor 99D 0.0031 0.0061 0.0108
Schistosoma mansoni transcription factor LCR-F1 0.0121 0.0499 0.0497
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0022 0.0017 0.0032
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0386 0.1794 0.1857
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0031 0.0061 0.006
Echinococcus granulosus intersectin 2 0.0028 0.0045 0.0047
Echinococcus granulosus neuropeptide s receptor 0.0031 0.0061 0.0063
Echinococcus granulosus g protein coupled receptor 0.0031 0.0061 0.0063
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0045 0.0046
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0105 0.0137
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Loa Loa (eye worm) hypothetical protein 0.0037 0.0092 0.0177
Loa Loa (eye worm) hypothetical protein 0.0037 0.0092 0.0177
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0026 0.0035 0.0036
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0583 0.1116
Echinococcus granulosus tubulin alpha chain 0.0083 0.0317 0.0328
Mycobacterium ulcerans cell division protein FtsZ 0.0019 0.0005 0.0004
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0132 0.0553 0.246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0145 0.0595
Brugia malayi Tubulin beta chain 0.0025 0.0033 0.0055
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.011 0.0449
Loa Loa (eye worm) voltage-gated calcium channel 0.0072 0.026 0.0497
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0436 0.0835
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0579 0.2738 0.5241
Echinococcus multilocularis tyrosine kinase 0.0129 0.0542 0.0561
Leishmania major DNA polymerase eta, putative 0.0039 0.0101 0.0194
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0061 0.0063
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Echinococcus multilocularis tubulin subunit beta 0.0045 0.0129 0.0133
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0024 0.0025 0.0106
Entamoeba histolytica BAR/SH3 domain containing protein 0.0028 0.0045 0.0094
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0061 0.0063
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0029 0.0049 0.0051
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.0226 0.0425
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0041 0.0107 0.0441
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0045 0.0186
Plasmodium falciparum DNA topoisomerase 2 0.0462 0.2169 0.2953
Echinococcus multilocularis beta tubulin 0.0045 0.0129 0.0133
Trypanosoma cruzi tubulin delta chain 0.0019 0.0005 0.0009
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0119 0.0489 0.0506
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0061 0.0063
Echinococcus granulosus expressed conserved protein 0.0029 0.0049 0.0051
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0041 0.0107 0.0144
Plasmodium vivax DNA gyrase subunit A, putative 0.152 0.7334 1
Chlamydia trachomatis DNA gyrase subunit B 0.0847 0.4049 0.552
Echinococcus multilocularis dna polymerase eta 0.0039 0.0101 0.0105
Leishmania major hypothetical protein, conserved 0.0037 0.0092 0.0177
Mycobacterium leprae Probable lipase LipE 0.0037 0.0092 0.0177
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0053 0.0169 0.0175
Loa Loa (eye worm) integrin alpha pat-2 0.002 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.007
Mycobacterium ulcerans DNA polymerase IV 0.0054 0.0175 0.0236
Echinococcus multilocularis snurportin 1 0.0173 0.0757 0.0784
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0119 0.0489 0.0665
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0028 0.0049 0.005
Loa Loa (eye worm) TYRA-2 protein 0.0031 0.0061 0.0117
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0052 0.0068
Leishmania major phosphatidylinositol 3-kinase, putative 0.0022 0.0016 0.003
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.1088 0.5224 0.7122
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0063 0.0215 0.0223
Echinococcus multilocularis 0.0029 0.0049 0.0051
Plasmodium falciparum serine/threonine protein kinase, putative 0.0132 0.0553 0.0748
Loa Loa (eye worm) hypothetical protein 0.0288 0.1315 0.2517
Leishmania major calcium channel protein, putative,ion transporter, putative 0.017 0.0742 0.142
Trypanosoma brucei zeta tubulin, putative 0.0019 0.0005 0.0006
Echinococcus multilocularis glutamate receptor 2 0.1082 0.5197 0.538
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0063 0.0215 0.0223
Trichomonas vaginalis tubulin epsilon chain, putative 0.0019 0.0005 0.0019
Toxoplasma gondii ABC1 family protein 0.0037 0.0092 0.0124
Schistosoma mansoni hypothetical protein 0.0028 0.0045 0.0044
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0079 0.0106
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0029 0.0049 0.0094
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0062 0.0211 0.0395
Loa Loa (eye worm) hypothetical protein 0.0056 0.0185 0.0354
Plasmodium vivax heat shock protein 86, putative 0.0041 0.0107 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0147 0.0602
Entamoeba histolytica unconventional myosin IB 0.0028 0.0045 0.0094
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0105 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0045 0.0186
Brugia malayi P38 map kinase family protein 2 0.0052 0.0163 0.0303
Brugia malayi Dopamine receptor 0.0031 0.0061 0.0108
Toxoplasma gondii beta-tubulin, putative 0.0045 0.0129 0.0173
Trypanosoma cruzi casein kinase, putative 0.0024 0.0027 0.0052
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0052 0.0064
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0061 0.0117
Echinococcus multilocularis tubulin alpha chain 0.0083 0.0317 0.0328
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0061 0.006
Schistosoma mansoni tubulin subunit beta 0.0045 0.0129 0.0127
Onchocerca volvulus 0.0031 0.0061 0.0117
Leishmania major DNA polymerase eta, putative 0.0021 0.0014 0.0028
Echinococcus multilocularis lamin dm0 0.0057 0.019 0.0196
Trypanosoma cruzi alpha tubulin, putative 0.0083 0.0317 0.0606
Schistosoma mansoni DNA topoisomerase II 0.0462 0.2169 0.2168
Echinococcus multilocularis Tubulin beta 2C chain 0.0045 0.0129 0.0133
Entamoeba histolytica acyl-CoA synthetase, putative 0.0035 0.0079 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0175 0.0331
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0121 0.0499 0.0516
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0143 0.0586
Echinococcus granulosus voltage gated hydrogen channel 1 0.0072 0.026 0.0269
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0078 0.0292 0.0392
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0029 0.0049 0.0047
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0092 0.0379
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0061 0.0081
Toxoplasma gondii LsmAD domain-containing protein 0.0066 0.0231 0.0313
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0072 0.026 0.0269
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0035 0.0079 0.0106
Loa Loa (eye worm) calcium channel 0.0072 0.026 0.0497
Brugia malayi Variant SH3 domain containing protein 0.0056 0.0185 0.0346
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Schistosoma mansoni opsin-like receptor 0.0031 0.0061 0.006
Onchocerca volvulus 0.0028 0.0045 0.0087
Brugia malayi hypothetical protein 0.0047 0.0141 0.0261
Loa Loa (eye worm) hypothetical protein 0.0107 0.0432 0.0826
Echinococcus multilocularis transient receptor potential cation channel 0.0076 0.028 0.0289
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0027 0.0026
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0061 0.0063
Entamoeba histolytica hypothetical protein 0.0121 0.0499 0.2208
Brugia malayi Variant SH3 domain containing protein 0.0056 0.0185 0.0346
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0077 0.0288 0.0298
Schistosoma mansoni tubulin subunit epsilon 0.0045 0.0129 0.0127
Brugia malayi Serotonin receptor 0.0031 0.0061 0.0108
Entamoeba histolytica tubulin gamma chain 0.0045 0.0129 0.0481
Echinococcus multilocularis casein kinase I gamma 0.0037 0.009 0.0093
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0143 0.0193
Trypanosoma cruzi casein kinase, putative 0.0024 0.0027 0.0052
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0079 0.0106
Brugia malayi serine/threonine protein kinase 6 0.0132 0.0553 0.105
Echinococcus multilocularis rho GTPase activating protein 20 0.0092 0.0361 0.0373
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0028 0.0049 0.0047
Echinococcus granulosus tubulin delta chain 0.0019 0.0005 0.0005
Brugia malayi serine/threonine kinase 12 0.0132 0.0553 0.105
Plasmodium vivax tubulin alpha chain, putative 0.0083 0.0317 0.0426
Schistosoma mansoni tubulin subunit alpha 0.0083 0.0317 0.0315
Schistosoma mansoni hypothetical protein 0.0545 0.2573 0.2571
Schistosoma mansoni patched 1 0.0028 0.0047 0.0045
Plasmodium falciparum endoplasmin, putative 0.0041 0.0107 0.014
Echinococcus granulosus tumor protein p63 0.0478 0.2246 0.2325
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0065 0.0226 0.0225
Echinococcus multilocularis Tubulin beta 2C chain 0.0045 0.0129 0.0133
Trypanosoma cruzi acetyl-CoA carboxylase 0.0086 0.0331 0.0633
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0031 0.0061 0.006
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.015 0.0641 0.1226
Brugia malayi RNA, U transporter 1 0.0046 0.0135 0.025
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0041 0.0107 0.014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0092 0.0177
Schistosoma mansoni tubulin subunit beta 0.0019 0.0005 0.0003
Echinococcus granulosus Tubulin beta 2C chain 0.0045 0.0129 0.0133
Brugia malayi Pre-SET motif family protein 0.006 0.0201 0.0376
Echinococcus granulosus survival motor neuron protein 1 0.0302 0.1387 0.1436
Schistosoma mansoni formin binding protein and related proteins 0.0028 0.0045 0.0044
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0462 0.2169 0.4146
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0175 0.0331
Echinococcus multilocularis mitogen activated protein kinase 14 0.0052 0.0163 0.0168
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0132 0.0553 0.0572
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.026 0.0352
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0201 0.0199
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.005 0.0155 0.0154
Brugia malayi protein-tyrosine kinase 0.0039 0.0102 0.0186
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0072 0.026 0.0269
Toxoplasma gondii transporter, cation channel family protein 0.0072 0.026 0.0352
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0045 0.0078
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0113 0.046 0.088
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0029 0.0049 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0061 0.006
Schistosoma mansoni hypothetical protein 0.0042 0.0116 0.0115
Echinococcus multilocularis potassium voltage gated channel protein 0.0072 0.026 0.0269
Echinococcus granulosus tyrosine protein kinase Src64B 0.0067 0.0238 0.0246
Echinococcus multilocularis voltage dependent calcium channel 0.0072 0.026 0.0269
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0061 0.0063
Echinococcus granulosus neuropeptide receptor 0.0031 0.0061 0.0063
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0123 0.0162
Echinococcus multilocularis casein kinase I alpha 0.0024 0.0027 0.0028
Loa Loa (eye worm) guanylate kinase 0.0028 0.0045 0.0087
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0045 0.0078
Echinococcus granulosus potassium voltage gated channel protein 0.0072 0.026 0.0269
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.049 0.0667
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Toxoplasma gondii transporter, cation channel family protein 0.0072 0.026 0.0352
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0129 0.0542 0.1037
Echinococcus multilocularis somatostatin receptor 0.0031 0.0061 0.0063
Echinococcus multilocularis transient receptor potential cation channel 0.0072 0.026 0.0269
Brugia malayi prolyl oligopeptidase family protein 0.015 0.0641 0.1219
Toxoplasma gondii target of rapamycin (TOR), putative 0.0048 0.0145 0.0196
Echinococcus multilocularis serotonin receptor 0.0031 0.0061 0.0063
Trypanosoma brucei unspecified product 0.0035 0.008 0.015
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0078 0.0292 0.0291
Echinococcus granulosus intermediate filament protein 0.0057 0.019 0.0196
Echinococcus multilocularis SH2 motif 0.0029 0.0049 0.0051
Onchocerca volvulus 0.0022 0.0017 0.0032
Loa Loa (eye worm) hypothetical protein 0.0037 0.0088 0.0168
Echinococcus multilocularis two pore calcium channel protein 1 0.0072 0.026 0.0269
Leishmania major dihydrofolate reductase-thymidylate synthase 0.1088 0.5224 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.019 0.0363
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Giardia lamblia Fructose-bisphosphate aldolase 0.0282 0.1289 0.6533
Echinococcus multilocularis shaker cognate 0.0072 0.026 0.0269
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.1082 0.5197 0.538
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0031 0.0061 0.0117
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0072 0.026 0.0269
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0067 0.0238 0.0246
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0082 0.0308 0.0581
Schistosoma mansoni lamin 0.0057 0.019 0.0188
Entamoeba histolytica BAR/SH3 domain containing protein 0.0028 0.0045 0.0094
Trichomonas vaginalis AGC family protein kinase 0.0132 0.0553 0.2267
Toxoplasma gondii transporter, cation channel family protein 0.0072 0.026 0.0352
Treponema pallidum DNA topoisomerase I (topA) 0.0092 0.0361 0.0486
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0123 0.0457
Brugia malayi Tubulin beta-1 chain 0.0045 0.0129 0.0238
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0014 0.0028
Echinococcus granulosus transient receptor potential cation channel 0.0072 0.026 0.0269
Echinococcus multilocularis mitogen activated protein kinase 14 0.0052 0.0163 0.0168
Brugia malayi olfactory channel protein osm-9 0.0076 0.028 0.0527
Trichomonas vaginalis tubulin beta chain, putative 0.0083 0.0317 0.1299
Schistosoma mansoni hypothetical protein 0.0052 0.0164 0.0162
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Schistosoma mansoni DNA polymerase eta 0.0039 0.0101 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.008 0.0329
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0061 0.0117
Brugia malayi Carboxyl transferase domain containing protein 0.0134 0.0566 0.1076
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0072 0.026 0.0489
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0065 0.0226 0.0938
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0061 0.0063
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0432 0.0587
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0045 0.0094
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0436 0.0832
Brugia malayi AKH receptor 0.0031 0.0061 0.0108
Echinococcus multilocularis mitogen activated protein kinase 11 0.0052 0.0163 0.0168
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0061 0.0063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1289 0.5287
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0036 0.0047
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0061 0.0063
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.152 0.7334 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0129 0.0539 0.0558
Echinococcus granulosus two pore calcium channel protein 2 0.0072 0.026 0.0269
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0041 0.0107 0.0144
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0711 0.3382 0.6473
Echinococcus granulosus transient receptor potential cation channel 0.0072 0.026 0.0269
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Trypanosoma brucei alpha tubulin 0.0083 0.0317 0.0603
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.152 0.7334 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0038 0.0093 0.0178
Brugia malayi follicle stimulating hormone receptor 0.0196 0.0869 0.1656
Echinococcus granulosus tyrosine protein kinase Src42A 0.0029 0.0049 0.0051
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0067 0.0238 0.0246
Trichomonas vaginalis tubulin, putative 0.0019 0.0005 0.0019
Schistosoma mansoni glutamate receptor kainate 0.0964 0.4617 0.4616
Chlamydia trachomatis DNA topoisomerase I 0.0092 0.0361 0.049
Leishmania major trypanothione reductase 0.0047 0.0139 0.0265
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0041 0.0107 0.0144
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.049 0.0667
Loa Loa (eye worm) hypothetical protein 0.0129 0.0542 0.1037
Schistosoma mansoni tubulin subunit beta 0.0045 0.0129 0.0127
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.008 0.0329
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0026 0.0035 0.0036
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0201 0.0208
Plasmodium falciparum tubulin epsilon chain, putative 0.0045 0.0129 0.0169
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0026 0.0035 0.0067
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0386 0.1794 0.1857
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0132 0.0553 0.246
Echinococcus granulosus SH2 motif 0.0029 0.0049 0.0051
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0019 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0119 0.0489 0.0936
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.005 0.0155 0.0297
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0061 0.0063
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.015 0.0641 0.0663
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0026 0.0035 0.0034
Trichomonas vaginalis CK1 family protein kinase 0.0024 0.0027 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0226 0.0929
Brugia malayi Src substrate cortactin 0.0028 0.0045 0.0078
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0072 0.026 0.0258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0145 0.0595
Trypanosoma brucei DNA topoisomerase III, putative 0.0092 0.0361 0.0688
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Schistosoma mansoni neuropeptide receptor 0.0031 0.0061 0.006
Loa Loa (eye worm) tubulin alpha 2 0.0064 0.0221 0.0424
Trichomonas vaginalis tubulin beta chain, putative 0.0045 0.0129 0.0527
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0123 0.0605
Entamoeba histolytica hypothetical protein 0.0119 0.0489 0.2163
Schistosoma mansoni neuropeptide f receptor 76f 0.0031 0.0061 0.006
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0077 0.0288 0.0286
Echinococcus multilocularis dro:myosuppressin receptor 0.0031 0.0061 0.0063
Echinococcus multilocularis potassium voltage gated channel protein 0.0072 0.026 0.0269
Brugia malayi SRC-1 0.0067 0.0238 0.0447
Trypanosoma brucei heat shock protein, putative 0.0041 0.0107 0.0203
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0964 0.4618 0.6296
Onchocerca volvulus 0.0037 0.0092 0.0177
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0061 0.0063
Schistosoma mansoni hypothetical protein 0.0031 0.0061 0.006
Echinococcus granulosus orexin receptor type 2 0.0031 0.0061 0.0063
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Echinococcus granulosus casein kinase I alpha 0.0024 0.0027 0.0028
Schistosoma mansoni hypothetical protein 0.0027 0.0042 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0088 0.0165
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0029 0.0038
Echinococcus granulosus SH2 motif 0.0029 0.0049 0.0051
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0031 0.0061 0.0117
Trypanosoma cruzi heat shock protein 85, putative 0.0041 0.0107 0.0206
Echinococcus granulosus microsomal glutathione S transferase 3 0.0063 0.0216 0.0223
Trypanosoma cruzi DNA topoisomerase III, putative 0.0092 0.0361 0.069
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0386 0.1794 0.1857
Echinococcus multilocularis tyrosine protein kinase Srms 0.0039 0.0102 0.0105
Loa Loa (eye worm) hypothetical protein 0.007 0.0251 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0047 0.0192
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0052 0.0162 0.0307
Trichomonas vaginalis tubulin beta chain, putative 0.0083 0.0317 0.1299
Echinococcus granulosus g protein coupled receptor 0.0031 0.0061 0.0063
Loa Loa (eye worm) tubulin beta chain 0.0019 0.0005 0.0009
Echinococcus granulosus RUN 0.004 0.0105 0.0109
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0052 0.024
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0288 0.1181
Echinococcus multilocularis signal transduction protein lnk realted 0.0029 0.0049 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Schistosoma mansoni sorting nexin 0.0028 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0152
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0042 0.0116 0.012
Brugia malayi Variant SH3 domain containing protein 0.0029 0.0049 0.0085
Echinococcus multilocularis tubulin epsilon chain 0.0045 0.0129 0.0133
Loa Loa (eye worm) tubulin alpha chain 0.0083 0.0317 0.0606
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0041 0.0107 0.0206
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Brugia malayi Tubulin gamma chain 0.0045 0.0129 0.0238
Brugia malayi G-protein coupled receptor 0.0031 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.0037 0.0092 0.0177
Echinococcus multilocularis Spectrin alpha actinin 0.0028 0.0045 0.0047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Brugia malayi SH2 domain containing protein 0.0039 0.0102 0.0186
Echinococcus multilocularis tar DNA binding protein 0.0038 0.0093 0.0096
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0063 0.0215 0.0412
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Schistosoma mansoni transient receptor potential channel 4 0.0072 0.026 0.0258
Brugia malayi glutathione reductase 0.0047 0.0139 0.0257
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0092 0.0361 0.069
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0041 0.0107 0.0144
Echinococcus granulosus voltage dependent calcium channel 0.0072 0.026 0.0269
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0092 0.0124
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0061 0.0063
Trypanosoma brucei heat shock protein, putative 0.0041 0.0107 0.0203
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Brugia malayi Tyrosine-protein kinase abl-1 0.007 0.025 0.0471
Giardia lamblia Beta tubulin 0.0045 0.0129 0.0631
Schistosoma mansoni aryl hydrocarbon receptor 0.0071 0.0258 0.0257
Trichomonas vaginalis tubulin gamma chain, putative 0.0045 0.0129 0.0527
Trichomonas vaginalis esterase, putative 0.0037 0.0092 0.0379
Echinococcus multilocularis tubulin alpha 0.0045 0.0129 0.0133
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0072 0.026 0.0258
Brugia malayi hypothetical protein 0.0119 0.0489 0.0928
Schistosoma mansoni alpha-1 adrenergic receptor 0.0031 0.0061 0.006
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0436 0.0593
Onchocerca volvulus 0.0035 0.0079 0.0152
Echinococcus multilocularis sodium channel protein 0.017 0.0742 0.0768
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0061 0.0063
Mycobacterium leprae cell division protein FtsZ 0.0019 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0201
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0016 0.0021
Brugia malayi Calcitonin receptor-like protein seb-1 0.0134 0.0564 0.1071
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0101 0.0185
Trichomonas vaginalis sensor histidine kinase, putative 0.0041 0.0107 0.0441
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0436 0.0435
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0432 0.0587
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Echinococcus granulosus tubulin alpha 3 chain 0.0083 0.0317 0.0328
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0072 0.026 0.0258
Schistosoma mansoni apoptosis stimulating of P53 0.0028 0.0045 0.0044
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0061 0.0081
Schistosoma mansoni tubulin subunit alpha 0.0083 0.0317 0.0315
Leishmania major DNA topoisomerase 1A 0.0092 0.0361 0.069
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0052 0.0064
Echinococcus granulosus voltage dependent calcium channel 0.0072 0.026 0.0269
Giardia lamblia Pms1-like protein 0.0041 0.0107 0.0523
Echinococcus granulosus transient receptor potential gamma protein 0.0072 0.026 0.0269
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0029 0.0049 0.0051
Entamoeba histolytica hypothetical protein 0.0121 0.0499 0.2208
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0042 0.0116 0.0214
Leishmania major protein kinase, putative 0.0026 0.0039 0.0074
Onchocerca volvulus 0.0039 0.0102 0.0195
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0065 0.0226 0.043
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Onchocerca volvulus 0.0031 0.0061 0.0117
Giardia lamblia Encystation-specific protease 0.003 0.0055 0.0255
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.049 0.0667
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0063 0.0215 0.0214
Loa Loa (eye worm) hepatopoietin HPO2 0.0026 0.0035 0.0067
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Echinococcus multilocularis SH2 motif 0.0029 0.0049 0.0051
Loa Loa (eye worm) hypothetical protein 0.0054 0.0173 0.0332
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.014 0.0265
Trypanosoma brucei DNA topoisomerase II beta, putative 0.037 0.1717 0.3285
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0029 0.0049 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0201 0.0199
Echinococcus granulosus signal transduction protein lnk realted 0.0029 0.0049 0.0051
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Schistosoma mansoni tyrosine kinase 0.0129 0.0542 0.054
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0079 0.0106
Brugia malayi SH3 domain containing protein 0.0028 0.0045 0.0078
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0031 0.0061 0.0063
Onchocerca volvulus Tyrosine kinase homolog 0.0066 0.0234 0.0448
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0152 0.0654 0.0677
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0041 0.0107 0.0144
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0026 0.0036 0.0047
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0072 0.026 0.0489
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0092 0.0361 0.069
Schistosoma mansoni amine GPCR 0.0031 0.0061 0.006
Brugia malayi RNA recognition motif domain containing protein 0.0038 0.0093 0.017
Echinococcus granulosus casein kinase I alpha 0.0024 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0072 0.026 0.0489
Echinococcus multilocularis G protein coupled receptor 139 0.0243 0.1095 0.1133
Schistosoma mansoni rab6-interacting 0.004 0.0105 0.0104
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0436 0.1789
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.1088 0.5224 0.7123
Plasmodium falciparum glutathione reductase 0.0047 0.0139 0.0183
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0041 0.0107 0.0144
Schistosoma mansoni neuropeptide receptor 0.0031 0.0061 0.006
Echinococcus multilocularis growth factor receptor bound protein 2 0.0056 0.0185 0.0192
Trypanosoma cruzi PAB1-binding protein , putative 0.0066 0.0231 0.0442
Echinococcus granulosus TRP transient receptor potential channel 0.0072 0.026 0.0269
Trypanosoma brucei epsilon tubulin 0.0045 0.0129 0.0243
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0163 0.0703 0.0728
Echinococcus granulosus 7TM GPCR rhodopsin 0.0031 0.0061 0.0063
Schistosoma mansoni endoplasmin 0.0041 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 0.006 0.0201 0.0384
Trypanosoma cruzi tubulin delta chain 0.0019 0.0005 0.0009
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0072 0.026 0.0269
Leishmania major hypothetical protein, conserved 0.0026 0.0035 0.0067
Entamoeba histolytica hypothetical protein 0.0028 0.0045 0.0094
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0061 0.006
Brugia malayi G-protein coupled receptor 0.0031 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0072 0.026 0.0489
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0041 0.0107 0.0144
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.0134 0.0566 0.1084
Loa Loa (eye worm) hypothetical protein 0.021 0.0933 0.1787
Schistosoma mansoni dreadlocks/dock 0.0028 0.0045 0.0044
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Mycobacterium tuberculosis Cell division protein FtsZ 0.0019 0.0005 0.0004
Leishmania major 4-coumarate:coa ligase-like protein 0.0035 0.0079 0.0152
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0072 0.026 0.0489
Leishmania major gamma-tubulin 0.0045 0.0129 0.0246
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0031 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0061 0.0063
Loa Loa (eye worm) hypothetical protein 0.0066 0.0231 0.0442
Brugia malayi Integrin alpha pat-2 precursor 0.002 0.0009 0.0009
Brugia malayi Peripheral plasma membrane protein CASK 0.0028 0.0045 0.0078
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0041 0.0107 0.0144
Echinococcus multilocularis transient receptor potential gamma protein 0.0072 0.026 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0145 0.0595
Brugia malayi hypothetical protein 0.0517 0.2438 0.4662
Brugia malayi hypothetical protein 0.004 0.0105 0.0193
Schistosoma mansoni amine GPCR 0.0031 0.0061 0.006
Loa Loa (eye worm) TK/KIN16 protein kinase 0.007 0.0253 0.0485
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0101 0.0191
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0041 0.0107 0.0441
Onchocerca volvulus 0.0031 0.0061 0.0117
Onchocerca volvulus 0.0029 0.0049 0.0094
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0031 0.0061 0.0063
Onchocerca volvulus 0.0024 0.0027 0.0052
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.049 0.0939
Schistosoma mansoni alpha tubulin 0.0083 0.0317 0.0315
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Trichomonas vaginalis CK1 family protein kinase 0.0024 0.0027 0.0111
Echinococcus granulosus GPCR family 2 0.0042 0.0116 0.012
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0061 0.0077
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.1082 0.5197 0.538
Giardia lamblia Gamma tubulin 0.0045 0.0129 0.0631
Trypanosoma cruzi heat shock protein 85, putative 0.0041 0.0107 0.0206
Echinococcus multilocularis calcium activated potassium channel 0.0074 0.027 0.028
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0053 0.0169 0.0228
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0077 0.0288 0.0551
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0087
Loa Loa (eye worm) hypothetical protein 0.0059 0.0196 0.0375
Schistosoma mansoni voltage-dependent calcium channel 0.0072 0.026 0.0258
Echinococcus multilocularis ryanodine receptor 44f 0.0072 0.026 0.0269
Echinococcus multilocularis peroxisome assembly protein 26 0.0083 0.0317 0.0328
Brugia malayi GRF zinc finger family protein 0.0092 0.0361 0.0682
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0067 0.0238 0.0236
Trypanosoma brucei epsilon tubulin 0.0045 0.0129 0.0243
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0028 0.0045 0.0044
Echinococcus granulosus ryanodine receptor 44f 0.0072 0.026 0.0269
Echinococcus multilocularis hypothetical protein 0.0083 0.0317 0.0328
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0175 0.0331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0016 0.0064
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0029 0.0038
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.152 0.7334 1
Schistosoma mansoni tar DNA-binding protein 0.0038 0.0093 0.0092
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0041 0.0107 0.0203
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0418 0.1954 0.2663
Mycobacterium ulcerans lipase LipD 0.0037 0.0092 0.0124
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0029 0.0049 0.0051
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0054 0.0175 0.0717
Echinococcus granulosus mitogen activated protein kinase 0.0031 0.006 0.0062
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0196 0.0869 0.1663
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0092 0.0091
Loa Loa (eye worm) glutamate receptor 2 0.0964 0.4617 0.8838
Echinococcus granulosus transient receptor potential cation channel 0.0076 0.028 0.0289
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.011 0.0449
Echinococcus multilocularis tubulin alpha chain 0.0083 0.0317 0.0328
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0031 0.0061 0.0063
Brugia malayi tRNA modification GTPase TrmE family protein 0.0029 0.0049 0.0085
Echinococcus granulosus SH2 domain containing protein 7 0.0029 0.0049 0.0051
Brugia malayi sulfakinin receptor protein 0.0031 0.0061 0.0108
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0462 0.2169 0.4151
Brugia malayi Transient-receptor-potential like protein 0.0072 0.026 0.0489
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Echinococcus granulosus tyrosine kinase 0.0039 0.0102 0.0105
Loa Loa (eye worm) hypothetical protein 0.0037 0.0092 0.0177
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0031 0.0061 0.0108
Trypanosoma cruzi PAB1-binding protein , putative 0.0066 0.0231 0.0442
Schistosoma mansoni biogenic amine receptor 0.0031 0.0061 0.006
Schistosoma mansoni protein kinase 0.0129 0.0542 0.054
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0029 0.0049 0.0094
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0029 0.0052 0.01
Schistosoma mansoni tyrosine kinase 0.0067 0.0238 0.0236
Schistosoma mansoni nck2/grb4 0.0056 0.0185 0.0184
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0517 0.2438 0.4666
Plasmodium falciparum casein kinase 1 0.0024 0.0027 0.0031
Mycobacterium leprae Probable two component sensor kinase MprB 0.0041 0.0107 0.0206
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0031 0.0061 0.006
Echinococcus multilocularis transient receptor potential cation channel 0.0072 0.026 0.0269
Brugia malayi Protein kinase domain containing protein 0.0039 0.0102 0.0186
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.006 0.0204 0.0211
Echinococcus multilocularis SH2 domain containing protein 7 0.0029 0.0049 0.0051
Brugia malayi SH2 domain containing protein 0.0029 0.0049 0.0085
Loa Loa (eye worm) melatonin receptor type 1A 0.0031 0.0061 0.0117
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Echinococcus multilocularis G-protein coupled receptor, putative 0.0031 0.0061 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0226 0.0929
Giardia lamblia Kinase, CK1 Casein kinase 0.0024 0.0027 0.0115
Brugia malayi Protein kinase domain containing protein 0.0039 0.0102 0.0186
Loa Loa (eye worm) tubulin beta-4 chain 0.0045 0.0129 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.018 0.0738
Schistosoma mansoni cell polarity protein 0.0028 0.0045 0.0044
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0365 0.1691 0.169
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.0139 0.059 0.0611
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.1088 0.5224 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0099 0.0405
Schistosoma mansoni alpha tubulin 0.0083 0.0317 0.0315
Plasmodium falciparum DNA gyrase subunit A 0.152 0.7334 1
Trypanosoma cruzi zeta tubulin, putative 0.0019 0.0005 0.0009
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0067 0.0235 0.0233
Onchocerca volvulus 0.0072 0.026 0.0497
Mycobacterium tuberculosis Possible two component sensor kinase 0.0041 0.0107 0.0144
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0072 0.026 0.0269
Entamoeba histolytica protein kinase , putative 0.0132 0.0553 0.246
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0035 0.0079 0.0106
Loa Loa (eye worm) hypothetical protein 0.016 0.0693 0.1327
Echinococcus granulosus tubulin alpha chain 0.0083 0.0317 0.0328
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0098 0.0097
Loa Loa (eye worm) phosphatidylinositol 3 0.0065 0.0226 0.0433
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.005 0.0155 0.0294
Echinococcus granulosus expressed conserved protein 0.0062 0.021 0.0218
Toxoplasma gondii DNA topoisomerase 2, putative 0.0462 0.2169 0.2956
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0026 0.0035 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0436 0.1789
Echinococcus multilocularis glutamate receptor 2 0.0964 0.4617 0.4779
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0053 0.0169 0.032
Echinococcus granulosus tyrosine protein kinase Lyn 0.0069 0.0248 0.0257
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1289 0.5287
Mycobacterium ulcerans DNA polymerase IV 0.0054 0.0175 0.0236
Schistosoma mansoni protein kinase 0.0132 0.0553 0.0551
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Trypanosoma brucei Heat shock protein 83, putative 0.0041 0.0107 0.0203
Echinococcus multilocularis allatostatin A receptor 0.0031 0.0061 0.0063
Onchocerca volvulus 0.0031 0.0061 0.0117
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Trypanosoma brucei alpha tubulin 0.0083 0.0317 0.0603
Giardia lamblia Beta tubulin 0.0045 0.0129 0.0631
Echinococcus granulosus glutamate receptor 2 0.1082 0.5197 0.538
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0028 0.0045 0.0087
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0028 0.0045 0.0087
Loa Loa (eye worm) ion channel NompC 0.0072 0.026 0.0497
Toxoplasma gondii pyruvate carboxylase 0.0053 0.0169 0.0228
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0028 0.0045 0.0087
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0029 0.0049 0.0094
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0061 0.0063
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0553 0.0551
Treponema pallidum fructose-bisphosphate aldolase 0.0282 0.1289 0.1752
Echinococcus granulosus mitogen activated protein kinase 11 0.0052 0.0163 0.0168
Chlamydia trachomatis DNA gyrase subunit B 0.0964 0.4618 0.6296
Trypanosoma brucei heat shock protein, putative 0.0041 0.0107 0.0203
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.003 0.0055 0.0068
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0077 0.0288 0.0298
Echinococcus granulosus tubulin beta 1 chain 0.0045 0.0129 0.0133
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0092 0.0361 0.0373
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0041 0.0107 0.0144
Schistosoma mansoni single-minded 0.0071 0.0258 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0092 0.0177
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0029 0.0049 0.0051
Trichomonas vaginalis tubulin gamma chain, putative 0.0019 0.0005 0.0019
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0026 0.0035 0.0067
Toxoplasma gondii DNA topoisomerase family protein 0.0092 0.0361 0.049
Echinococcus multilocularis SHC transforming protein 3 0.0029 0.0049 0.0051
Trichomonas vaginalis tubulin epsilon chain, putative 0.0045 0.0129 0.0527
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0041 0.0107 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0175 0.0331
Onchocerca volvulus 0.0039 0.0102 0.0195
Echinococcus multilocularis tyrosine protein kinase shark 0.0043 0.0122 0.0126
Trypanosoma brucei heat shock protein, putative 0.0041 0.0107 0.0203
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0436 0.1916
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0065 0.0226 0.043
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0031 0.0061 0.006
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0061 0.0077
Echinococcus multilocularis heat shock protein 0.0041 0.0107 0.0111
Schistosoma mansoni Dab2-interacting protein-like 0.0028 0.0045 0.0044
Leishmania major 4-coumarate:coa ligase-like protein 0.0035 0.0079 0.0152
Echinococcus multilocularis transfer RNA-Lys 0.0053 0.0168 0.0173
Brugia malayi neuropeptide F receptor 0.0031 0.0061 0.0108
Onchocerca volvulus 0.0031 0.0061 0.0117
Loa Loa (eye worm) hypothetical protein 0.0119 0.0489 0.0936
Echinococcus multilocularis tyrosine protein kinase Abl 0.011 0.0449 0.0465
Leishmania major DNA topoisomerase III, putative 0.0092 0.0361 0.069
Schistosoma mansoni vav2 0.0029 0.0052 0.005
Trichomonas vaginalis receptor histidine kinase, putative 0.0041 0.0107 0.0441
Schistosoma mansoni lamin 0.0057 0.019 0.0188
Toxoplasma gondii hypothetical protein 0.0072 0.026 0.0352
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0061 0.0063
Echinococcus granulosus tubulin alpha 1C chain 0.0083 0.0317 0.0328
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0061 0.0117
Echinococcus multilocularis Niemann Pick C1 protein 0.0066 0.023 0.0238
Loa Loa (eye worm) voltage-gated potassium channel 0.0072 0.026 0.0497
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0078 0.0292 0.0392
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0583 0.0793
Schistosoma mansoni tubulin subunit delta 0.0019 0.0005 0.0003
Trypanosoma cruzi Heat shock protein 83, putative 0.0041 0.0107 0.0206
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0052 0.0064
Echinococcus granulosus tachykinin peptides receptor 99D 0.0031 0.0061 0.0063
Loa Loa (eye worm) hypothetical protein 0.0119 0.0489 0.0936
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0022 0.0016 0.0016
Trichomonas vaginalis heat shock protein, putative 0.0041 0.0107 0.0441
Trichomonas vaginalis tubulin gamma chain, putative 0.0045 0.0129 0.0527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0115 0.0472
Schistosoma mansoni neuropeptide receptor 0.0031 0.0061 0.006
Schistosoma mansoni lipoxygenase 0.0174 0.0762 0.076
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0061 0.0063
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0143 0.0193
Trypanosoma cruzi zeta tubulin, putative 0.0019 0.0005 0.0009
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0092 0.0361 0.0359
Entamoeba histolytica tubulin alpha chain, putative 0.0083 0.0317 0.1359
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0039 0.0102 0.0105
Brugia malayi Receptor family ligand binding region containing protein 0.0119 0.0489 0.0928
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.1088 0.5224 0.5224
Mycobacterium tuberculosis Conserved protein 0.0037 0.0092 0.0124
Plasmodium vivax tubulin beta chain, putative 0.0045 0.0129 0.0169
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0061 0.006
Echinococcus multilocularis casein kinase I delta 0.0024 0.0027 0.0028
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Entamoeba histolytica tubulin family protein 0.0045 0.0129 0.0481
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0031 0.0061 0.0108
Brugia malayi putative neuropeptide receptor NPR1 0.0031 0.0061 0.0108
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0039 0.0102 0.0357
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.0517 0.0989
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.007
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0067 0.0238 0.0246
Onchocerca volvulus 0.0031 0.0061 0.0117
Loa Loa (eye worm) AUR protein kinase 0.0132 0.0553 0.1058
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0087
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0035 0.0079 0.0106
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0072 0.026 0.0258
Brugia malayi Fes/CIP4 homology domain containing protein 0.0028 0.0045 0.0078
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Echinococcus multilocularis dna polymerase kappa 0.0054 0.0175 0.0181
Schistosoma mansoni polycystin 1-related 0.004 0.0105 0.0104
Trypanosoma brucei developmentally regulated phosphoprotein 0.0041 0.0107 0.0203
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.006 0.0204 0.0211
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0132 0.0553 0.0572
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0143 0.0189
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Brugia malayi ImpB/MucB/SamB family protein 0.0026 0.0035 0.0059
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Echinococcus granulosus casein kinase i 0.0024 0.0027 0.0028
Loa Loa (eye worm) SH2 domain-containing protein 0.0029 0.0049 0.0094
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0019 0.0002 0.0003
Echinococcus granulosus beta tubulin 0.0045 0.0129 0.0133
Schistosoma mansoni tyrosine kinase 0.0067 0.0238 0.0236
Plasmodium falciparum DNA gyrase subunit B 0.0964 0.4618 0.6295
Giardia lamblia DNA topoisomerase II 0.0422 0.1971 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0201 0.0199
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0119 0.0489 0.0936
Echinococcus granulosus atrial natriuretic peptide receptor 0.0119 0.0489 0.0506
Leishmania major protein kinase, putative 0.0021 0.001 0.002
Onchocerca volvulus Neuropeptide F receptor homolog 0.0031 0.0061 0.0117
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0579 0.2738 0.5241
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0113 0.046 0.0872
Brugia malayi RNA binding protein 0.0038 0.0093 0.017
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0092 0.0361 0.069
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0045 0.0078
Schistosoma mansoni cellular tumor antigen P53 0.007 0.0251 0.025
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0061 0.0063
Schistosoma mansoni tubulin subunit alpha 0.0019 0.0005 0.0003
Schistosoma mansoni metabotropic glutamate receptor 0.0119 0.0489 0.0488
Trypanosoma brucei tubulin gamma chain 0.0045 0.0129 0.0243
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1289 0.5287
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0029 0.0049 0.0051
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.1289 0.5895
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Schistosoma mansoni tubulin subunit alpha 0.0083 0.0317 0.0315
Trichomonas vaginalis AGC family protein kinase 0.0132 0.0553 0.2267
Loa Loa (eye worm) hypothetical protein 0.0082 0.0308 0.0589
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Brugia malayi Sex muscle abnormal protein 5 0.0056 0.0185 0.0346
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0386 0.1794 0.1857
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0019
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0028 0.0045 0.0047
Loa Loa (eye worm) TOPoisomerase family member 0.0462 0.2169 0.4151
Echinococcus multilocularis aurora kinase A 0.0132 0.0553 0.0572
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0139 0.0143
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0026 0.0035 0.0036
Echinococcus multilocularis Niemann Pick C1 protein 0.0094 0.0367 0.038
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0052 0.0122
Brugia malayi Guanylyl cyclase protein 23 0.0129 0.0542 0.103
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0041 0.0107 0.0111
Brugia malayi tubulin alpha chain - mouse 0.0083 0.0317 0.0598
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.152 0.7334 1
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.017 0.0742 0.0768
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0072 0.026 0.0269
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0061 0.0063
Echinococcus granulosus tyrosine kinase 0.0039 0.0102 0.0105
Mycobacterium tuberculosis Probable reductase 0.0107 0.0432 0.0587
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0053 0.0169 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0045 0.0186
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0119 0.0489 0.0506
Brugia malayi DNA topoisomerase III 0.0092 0.0361 0.0682
Trypanosoma brucei tubulin delta chain 0.0019 0.0005 0.0006
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0061 0.006
Giardia lamblia Alpha-tubulin 0.0083 0.0317 0.1587
Echinococcus granulosus mitogen activated protein kinase 3 0.0031 0.006 0.0062
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0041 0.0107 0.0144
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0067 0.0238 0.0246
Onchocerca volvulus 0.0029 0.0049 0.0094
Toxoplasma gondii heat shock protein 90, putative 0.0041 0.0107 0.0144
Schistosoma mansoni biogenic amine receptor 0.0031 0.0061 0.006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0061 0.0063
Onchocerca volvulus 0.0119 0.0489 0.0936
Schistosoma mansoni transient receptor potential channel 0.0076 0.028 0.0278
Entamoeba histolytica DNA topoisomerase III, putative 0.0092 0.0361 0.1564
Trichomonas vaginalis tubulin alpha chain, putative 0.0045 0.0129 0.0527
Echinococcus granulosus tyrosine protein kinase Blk 0.0039 0.0102 0.0105
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0045 0.0129 0.0173
Loa Loa (eye worm) RGC/RGC protein kinase 0.0129 0.0542 0.1037
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0061 0.0063
Onchocerca volvulus 0.0037 0.0092 0.0177
Schistosoma mansoni hypothetical protein 0.0042 0.0116 0.0115
Echinococcus granulosus somatostatin receptor 0.0031 0.0061 0.0063
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0045 0.0094
Brugia malayi prolyl oligopeptidase family protein 0.005 0.0155 0.0289
Loa Loa (eye worm) hypothetical protein 0.016 0.0693 0.1327
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0019 0.0002 0.0003
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.005 0.0155 0.021
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0072 0.026 0.0489
Echinococcus granulosus voltage gated potassium channel 0.0082 0.0308 0.0318
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0061 0.0063
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0105 0.0109
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.1082 0.5197 0.538
Echinococcus granulosus Niemann Pick C1 protein 0.0066 0.023 0.0238
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0031 0.0056
Loa Loa (eye worm) SH2 domain-containing protein 0.0029 0.0049 0.0094
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0029 0.0049 0.0047
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0028 0.0045 0.0044
Brugia malayi Guanylate kinase family protein 0.0028 0.0045 0.0078
Schistosoma mansoni hypothetical protein 0.0173 0.0757 0.0755
Loa Loa (eye worm) endoplasmin 0.0041 0.0107 0.0206
Brugia malayi cation channel family protein 0.0072 0.026 0.0489
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0092 0.0124
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0079 0.0106
Giardia lamblia Heat shock protein HSP 90-alpha 0.0041 0.0107 0.0523
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0113 0.046 0.0476
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Mycobacterium tuberculosis Conserved protein 0.0041 0.0107 0.0144
Onchocerca volvulus 0.0037 0.0092 0.0177
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0041 0.0107 0.0441
Brugia malayi intermediate filament protein 0.0057 0.019 0.0355
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.1996 0.966 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Echinococcus multilocularis lamin 0.0057 0.019 0.0196
Schistosoma mansoni opsin-like receptor 0.0031 0.0061 0.006
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0031 0.0061 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0063 0.0215 0.0214
Echinococcus granulosus growth factor receptor bound protein 2 0.0056 0.0185 0.0192
Trypanosoma brucei PAB1-binding protein , putative 0.0066 0.0231 0.0439
Loa Loa (eye worm) BEN-1 protein 0.0045 0.0129 0.0246
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.01
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0134 0.0564 0.1079
Echinococcus granulosus transient receptor potential cation channel 0.0072 0.026 0.0269
Echinococcus multilocularis tubulin gamma 1 chain 0.0045 0.0129 0.0133
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0031 0.006 0.0114
Echinococcus multilocularis N chimaerin 0.0029 0.0049 0.0051
Loa Loa (eye worm) hypothetical protein 0.0058 0.0193 0.0369
Echinococcus multilocularis potassium large conductance calcium activated 0.0072 0.026 0.0269
Trichomonas vaginalis tubulin beta chain, putative 0.0083 0.0317 0.1299
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0029 0.0049 0.0094
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0072 0.026 0.0258
Echinococcus granulosus potassium voltage gated channel protein 0.0072 0.026 0.0269
Onchocerca volvulus 0.0031 0.0061 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0016 0.0064
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Echinococcus multilocularis short transient receptor potential channel 6 0.0072 0.026 0.0269
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0078 0.0292 0.0392
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0077 0.0288 0.0298
Echinococcus granulosus snurportin 1 0.0173 0.0757 0.0784
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0964 0.4618 0.6296
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0079 0.0143
Schistosoma mansoni microsomal glutathione s-transferase 0.0063 0.0216 0.0214
Echinococcus multilocularis voltage gated potassium channel 0.0082 0.0308 0.0318
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0063 0.0215 0.0214
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Echinococcus granulosus serotonin receptor 0.0031 0.0061 0.0063
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0082 0.0308 0.0318
Entamoeba histolytica acyl-coA synthetase, putative 0.0035 0.0079 0.0252
Trypanosoma brucei DNA topoisomerase IA, putative 0.0092 0.0361 0.0688
Leishmania major delta tubulin, putative 0.0019 0.0005 0.0009
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0029 0.0049 0.0051
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0041 0.0107 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0226 0.0929
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0061 0.0117
Schistosoma mansoni hypothetical protein 0.0092 0.0357 0.0355
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.006 0.0245
Plasmodium vivax acyl-CoA synthetase, putative 0.0026 0.0036 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.006 0.0058
Schistosoma mansoni transient receptor potential channel 0.0072 0.026 0.0258
Brugia malayi 6-phosphofructokinase 0.0108 0.0436 0.0827
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0087
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0082 0.0308 0.0318
Echinococcus granulosus suppressor of cytokine signaling 7 0.0029 0.0049 0.0051
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0077 0.0288 0.0286
Trypanosoma cruzi DNA topoisomerase III, putative 0.0092 0.0361 0.069
Brugia malayi bHLH-PAS transcription factor 0.0053 0.0168 0.0312
Onchocerca volvulus 0.0055 0.0177 0.0338
Schistosoma mansoni hypothetical protein 0.0049 0.0149 0.0147
Brugia malayi SH2 domain containing protein 0.0029 0.0049 0.0085
Trypanosoma brucei conserved protein 0.0028 0.0045 0.0084
Echinococcus granulosus transient receptor potential cation channel 0.0072 0.026 0.0269
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0035 0.0079 0.0152
Schistosoma mansoni hypothetical protein 0.0031 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Trypanosoma brucei aurora B kinase 0.0132 0.0553 0.1055
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0087
Echinococcus multilocularis tensin 0.0029 0.0049 0.0051
Onchocerca volvulus Putative cortactin 0.0028 0.0045 0.0087
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.1088 0.5224 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0201 0.0208
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0173 0.0757 0.1449
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0053 0.0169 0.0228
Trichomonas vaginalis p67phox protein, putative 0.0028 0.0045 0.0186
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0053 0.0169 0.0228
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0061 0.006
Brugia malayi hypothetical protein 0.0072 0.026 0.0489
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Entamoeba histolytica hypothetical protein 0.0028 0.0045 0.0094
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0072 0.026 0.0269
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.005 0.0155 0.0297
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0077 0.0288 0.0551
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0029 0.0049 0.0051
Echinococcus granulosus tubulin epsilon chain 0.0045 0.0129 0.0133
Giardia lamblia Alpha-tubulin 0.0083 0.0317 0.1587
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0016 0.0064
Echinococcus multilocularis transfer RNA-Gly 0.0072 0.026 0.0269
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0061 0.006
Giardia lamblia Beta tubulin 0.0045 0.0129 0.0631
Trypanosoma brucei beta tubulin 0.0045 0.0129 0.0243
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0061 0.0117
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0092 0.0361 0.0373
Brugia malayi metabotropic glutamate receptor type 2 0.0119 0.0489 0.0928
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0029 0.0049 0.0085
Schistosoma mansoni hypothetical protein 0.0028 0.0045 0.0044
Brugia malayi 6-phosphofructokinase 0.0108 0.0436 0.0827
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Echinococcus multilocularis integrin alpha ps 0.002 0.0009 0.001
Plasmodium falciparum tubulin beta chain 0.0045 0.0129 0.0169
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0029 0.0049 0.0047
Echinococcus granulosus tyrosine protein kinase Fyn 0.0067 0.0238 0.0246
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0021 0.001 0.002
Schistosoma mansoni dynamin-associated protein 0.0028 0.0045 0.0044
Plasmodium vivax ataxin-2 like protein, putative 0.0066 0.0231 0.0309
Leishmania major DNA polymerase kappa, putative 0.0033 0.007 0.0134
Echinococcus multilocularis Tubulin beta 2C chain 0.0045 0.0129 0.0133
Echinococcus multilocularis tubulin alpha 3 chain 0.0083 0.0317 0.0328
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1289 0.5287
Echinococcus granulosus tyrosine protein kinase Fyn 0.0067 0.0238 0.0246
Schistosoma mansoni growth factor receptor-bound protein 0.0056 0.0185 0.0184
Entamoeba histolytica hypothetical protein 0.0028 0.0045 0.0094
Echinococcus multilocularis tubulin alpha chain 0.0083 0.0317 0.0328
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0024 0.0027 0.0052
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0139 0.0143
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0061 0.0063
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0175 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0045 0.0186
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.008 0.0329
Entamoeba histolytica SH2 domain containing protein 0.0029 0.0049 0.011
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0019 0.0002 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0038 0.0093 0.0092
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0031 0.0061 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0019
Schistosoma mansoni SH2A 0.0029 0.0049 0.0047
Schistosoma mansoni opsin-like receptor 0.0031 0.0061 0.006
Trypanosoma brucei DNA topoisomerase III, putative 0.0092 0.0361 0.0688
Echinococcus granulosus single minded 2 0.0057 0.0187 0.0194
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.1289 0.5895
Brugia malayi hypothetical protein 0.0121 0.0499 0.0947
Schistosoma mansoni hypothetical protein 0.0031 0.0061 0.006
Echinococcus granulosus glutamate receptor NMDA 0.0983 0.4712 0.4878
Echinococcus granulosus SHC transforming protein 3 0.0029 0.0049 0.0051
Plasmodium vivax tubulin alpha chain, putative 0.0083 0.0317 0.0426
Brugia malayi Augmenter of liver regeneration 0.0026 0.0035 0.0058
Brugia malayi SH2 domain containing protein 0.0029 0.0049 0.0085
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Echinococcus granulosus peptide allatostatin:somatostatin 0.0031 0.0061 0.0063
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0061 0.006
Trypanosoma brucei alpha tubulin 0.0083 0.0317 0.0603
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0175 0.0331
Toxoplasma gondii casein kinase I 0.0024 0.0027 0.0035
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0035 0.0079 0.0106
Leishmania major acetyl-CoA carboxylase, putative 0.0139 0.059 0.1129
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0053 0.0169 0.0323
Onchocerca volvulus 0.0057 0.019 0.0363
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0024 0.0027 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0038 0.0093 0.0092
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0107 0.014
Echinococcus granulosus aurora kinase A 0.0132 0.0553 0.0572
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0964 0.4618 0.6295
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0028 0.0045 0.0047
Loa Loa (eye worm) tubulin alpha 2 0.0038 0.0097 0.0186
Brugia malayi Protein kinase domain containing protein 0.0039 0.0102 0.0186
Echinococcus granulosus Dipeptidyl peptidase 9 0.005 0.0155 0.0161
Echinococcus granulosus transient receptor potential cation channel 0.0072 0.026 0.0269
Echinococcus multilocularis transfer RNA-Ala 0.0028 0.0045 0.0047
Entamoeba histolytica hypothetical protein 0.0028 0.0049 0.0108
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0061 0.0063
Brugia malayi cytokine inducible SH2-containing protein 5 0.0029 0.0049 0.0085
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0028 0.0045 0.0044
Schistosoma mansoni alpha tubulin 0.0083 0.0317 0.0315
Echinococcus granulosus shaker cognate 0.0072 0.026 0.0269
Loa Loa (eye worm) casein kinase 0.0035 0.008 0.0153
Entamoeba histolytica DNA topoisomerase II, putative 0.0462 0.2169 1
Toxoplasma gondii aurora kinase 0.0132 0.0553 0.0752
Loa Loa (eye worm) beta-tubulin 0.0045 0.0129 0.0246
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0041 0.0107 0.0144
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0031 0.006 0.0114
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0067 0.0238 0.0246
Toxoplasma gondii thioredoxin reductase 0.0047 0.0139 0.0187
Brugia malayi SH2 domain containing protein 0.0029 0.0049 0.0085
Echinococcus granulosus Tubulin beta 2C chain 0.0045 0.0129 0.0133
Trichomonas vaginalis tubulin, putative 0.0025 0.0033 0.0137
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0026 0.0035 0.0067
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0092 0.0361 0.049
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0019 0.0002 0.0002
Brugia malayi TAR-binding protein 0.0038 0.0093 0.017
Loa Loa (eye worm) BEN-1 protein 0.0045 0.0129 0.0246
Toxoplasma gondii beta-1 tubulin, putative 0.0045 0.0129 0.0173
Echinococcus multilocularis tubulin alpha chain 0.0083 0.0317 0.0328
Echinococcus multilocularis voltage gated potassium channel 0.0072 0.026 0.0269
Trypanosoma cruzi beta tubulin, putative 0.0045 0.0129 0.0246
Leishmania major hypothetical protein, unknown function 0.0072 0.026 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0145 0.0595
Loa Loa (eye worm) protein-tyrosine kinase 0.0028 0.0045 0.0087
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0067 0.0238 0.0246
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Echinococcus granulosus heat shock protein 90 0.0041 0.0107 0.0111
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0029 0.0038
Brugia malayi Thioredoxin reductase 0.0047 0.0139 0.0257
Echinococcus granulosus beta tubulin 0.0045 0.0129 0.0133
Echinococcus multilocularis tyrosine kinase 0.0039 0.0102 0.0105
Schistosoma mansoni GTPase activating protein 0.0029 0.0049 0.0047
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Plasmodium vivax glutathione reductase, putative 0.0047 0.0139 0.0183
Mycobacterium ulcerans hypothetical protein 0.0035 0.0079 0.0106
Trypanosoma brucei heat shock protein, putative 0.0041 0.0107 0.0203
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0028 0.0049 0.005
Loa Loa (eye worm) glutamate receptor 1 0.0964 0.4617 0.8838
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0039 0.0102 0.0105
Echinococcus multilocularis g-protein coupled receptor 0.0031 0.0061 0.0063
Echinococcus granulosus sterol regulatory element binding protein 0.0028 0.0047 0.0049
Loa Loa (eye worm) protein kinase domain-containing protein 0.0037 0.009 0.0173
Entamoeba histolytica deoxycytidyl transferase, putative 0.0026 0.0035 0.0046
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0016 0.003
Echinococcus multilocularis Tubulin beta 2C chain 0.0045 0.0129 0.0133
Schistosoma mansoni tubulin subunit beta 0.0045 0.0129 0.0127
Loa Loa (eye worm) hypothetical protein 0.0064 0.0221 0.0424
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0027 0.0041 0.0076
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0042 0.0116 0.012
Trypanosoma brucei beta tubulin 0.0045 0.0129 0.0243
Echinococcus granulosus epidermal growth factor receptor kinase 0.0028 0.0045 0.0047
Loa Loa (eye worm) voltage-gated potassium channel 0.0072 0.026 0.0497
Echinococcus granulosus receptor type guanylyl cyclase 0.0129 0.0542 0.0561
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Loa Loa (eye worm) hypothetical protein 0.0076 0.028 0.0535
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.1088 0.5224 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0092 0.0124
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Trichomonas vaginalis tubulin epsilon chain, putative 0.0083 0.0317 0.1299
Trichomonas vaginalis tubulin beta chain, putative 0.0083 0.0317 0.1299
Echinococcus granulosus tubulin subunit beta 0.0045 0.0129 0.0133
Toxoplasma gondii beta tubulin 0.0045 0.0129 0.0173
Echinococcus multilocularis Dipeptidyl peptidase 9 0.005 0.0155 0.0161
Plasmodium falciparum DNA topoisomerase 3, putative 0.0092 0.0361 0.0486
Schistosoma mansoni voltage-gated ion channel 0.0072 0.026 0.0258
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0063 0.0215 0.0223
Echinococcus multilocularis tumor protein p63 0.0478 0.2246 0.2325
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0072 0.026 0.0258
Trypanosoma cruzi epsilon tubulin, putative 0.0045 0.0129 0.0246
Chlamydia trachomatis DNA gyrase subunit A 0.016 0.0693 0.0944
Mycobacterium ulcerans putative regultory protein 0.0041 0.0107 0.0144
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0436 0.0593
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0092 0.0124
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0061 0.006
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0077 0.0288 0.0298
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.006 0.0245
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1289 0.5287
Brugia malayi SH2 domain containing protein 0.0029 0.0049 0.0085
Echinococcus multilocularis conserved hypothetical protein 0.0072 0.026 0.0269
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0028 0.0047 0.009
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0041 0.0107 0.014
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0092 0.0096
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0065 0.0226 0.0234
Echinococcus granulosus potassium voltage gated channel protein 0.0072 0.026 0.0269
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0113 0.046 0.0476
Echinococcus multilocularis mitogen activated protein kinase 3 0.0031 0.006 0.0062
Echinococcus multilocularis intersectin 2 0.0028 0.0045 0.0047
Trichomonas vaginalis set domain proteins, putative 0.0473 0.2222 0.9115
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0041 0.0107 0.0144
Echinococcus multilocularis transient receptor potential cation channel 0.0076 0.028 0.0289
Echinococcus multilocularis neuropeptide receptor A26 0.0031 0.0061 0.0063
Brugia malayi SH2 domain containing protein 0.0039 0.0102 0.0186
Brugia malayi Glutamate receptor 2 precursor 0.0964 0.4617 0.8837
Loa Loa (eye worm) TK/ABL protein kinase 0.0152 0.0654 0.1252
Mycobacterium ulcerans DNA gyrase subunit B 0.0964 0.4618 0.6296
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0462 0.2169 0.2245
Schistosoma mansoni tar DNA-binding protein 0.0038 0.0093 0.0092
Entamoeba histolytica protein kinase domain containing protein 0.0132 0.0553 0.246
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Schistosoma mansoni C-fyn 0.0028 0.0045 0.0044
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.1082 0.5197 0.538
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0092 0.0177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0081 0.033
Brugia malayi Tubulin alpha-2 chain 0.0083 0.0317 0.0598
Echinococcus granulosus short transient receptor potential channel 6 0.0076 0.028 0.0289
Echinococcus granulosus tubulin alpha chain 0.0083 0.0317 0.0328
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0077 0.0288 0.0298
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0132 0.0553 0.246
Brugia malayi beta-lactamase 0.0037 0.0092 0.0168
Loa Loa (eye worm) hypothetical protein 0.0041 0.0107 0.0206
Entamoeba histolytica hypothetical protein 0.0028 0.0045 0.0094
Echinococcus multilocularis mitogen activated protein kinase 11 0.0052 0.0163 0.0168
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0105 0.0109
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0081 0.033
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0436 0.1916
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0274 0.1246 0.1244
Brugia malayi Protein kinase domain containing protein 0.0039 0.0102 0.0186
Trypanosoma cruzi epsilon tubulin, putative 0.0045 0.0129 0.0246
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0056 0.0185 0.0354
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0436 0.1916
Onchocerca volvulus 0.0039 0.0102 0.0195
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0139 0.0265
Trichomonas vaginalis tubulin beta chain, putative 0.0083 0.0317 0.1299
Echinococcus granulosus nmda type glutamate receptor 0.1102 0.5292 0.5478
Schistosoma mansoni integrin alpha-ps 0.002 0.0009 0.0008
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0019 0.0002 0.0003
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0072 0.026 0.0497
Schistosoma mansoni survival motor neuron protein 0.0062 0.0211 0.0209
Schistosoma mansoni growth hormone secretagogue receptor 0.0031 0.0061 0.006
Echinococcus multilocularis nostrin 0.0028 0.0045 0.0047
Echinococcus multilocularis tubulin alpha 1C chain 0.0083 0.0317 0.0328
Schistosoma mansoni hypothetical protein 0.0072 0.026 0.0258
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0035 0.0079 0.0152
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0119 0.0489 0.0661
Schistosoma mansoni tensin-related 0.0029 0.0049 0.0047
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0121 0.0499 0.0516
Echinococcus granulosus tubulin alpha chain 0.0083 0.0317 0.0328
Brugia malayi G protein-coupled receptor 0.0031 0.0061 0.0108
Onchocerca volvulus 0.0029 0.0049 0.0094
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0077 0.0288 0.0298
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0035 0.0046
Brugia malayi hypothetical protein 0.0038 0.0097 0.0178
Echinococcus multilocularis tubulin alpha 1C chain 0.0083 0.0317 0.0328
Echinococcus multilocularis integrin alpha ps 0.002 0.0009 0.001
Brugia malayi CHE-14 protein 0.0028 0.0047 0.0081
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0061 0.006
Schistosoma mansoni myosin xvIII 0.0031 0.0061 0.006
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Onchocerca volvulus 0.0057 0.019 0.0363
Brugia malayi Dopamine receptor protein 2 0.0031 0.0061 0.0108
Echinococcus granulosus sodium channel protein 0.017 0.0742 0.0768
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0087
Trypanosoma brucei protein kinase, putative 0.0031 0.006 0.0111
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0129 0.0539 0.0558
Brugia malayi tubulin alpha-2 chain 0.0083 0.0317 0.0598
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.006 0.0245
Schistosoma mansoni tar DNA-binding protein 0.0038 0.0093 0.0092
Schistosoma mansoni shc transforming protein 0.0029 0.0049 0.0047
Loa Loa (eye worm) thymidylate synthase 0.1088 0.5224 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0067 0.0238 0.0246
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0105 0.0109
Onchocerca volvulus 0.0062 0.0211 0.0403
Loa Loa (eye worm) hypothetical protein 0.0037 0.0092 0.0177
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Loa Loa (eye worm) alpha-tubulin 0.0083 0.0317 0.0606
Schistosoma mansoni hypothetical protein 0.0545 0.2573 0.2571
Onchocerca volvulus 0.0028 0.0045 0.0087
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0067 0.0238 0.0246
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0019 0.0005 0.0004
Onchocerca volvulus 0.1088 0.5224 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0201 0.0199
Echinococcus multilocularis tubulin alpha 3 chain 0.0083 0.0317 0.0328
Trypanosoma brucei heat shock protein, putative 0.0041 0.0107 0.0203
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.007
Brugia malayi ORL1-like opioid receptor 0.0031 0.0061 0.0108
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0061 0.0114
Schistosoma mansoni glutamate receptor AMPA 0.0964 0.4617 0.4616
Schistosoma mansoni tensin-related 0.0029 0.0049 0.0047
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0416 0.1941 0.3716
Onchocerca volvulus 0.003 0.0056 0.0107
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Brugia malayi Variant SH3 domain containing protein 0.0029 0.0052 0.0091
Brugia malayi Serotonin receptor 0.0031 0.0061 0.0108
Plasmodium falciparum tubulin gamma chain 0.0045 0.0129 0.0169
Echinococcus multilocularis expressed protein 0.0028 0.0045 0.0047
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0045 0.0078
Schistosoma mansoni vesicular amine transporter 0.0075 0.0278 0.0276
Onchocerca volvulus 0.0031 0.0061 0.0117
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0061 0.0117
Leishmania major protein kinase, putative 0.0132 0.0553 0.1058
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0072 0.026 0.0494
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0101 0.0194
Entamoeba histolytica hypothetical protein 0.0028 0.0045 0.0094
Entamoeba histolytica casein kinase 1, putative 0.0024 0.0027 0.0008
Echinococcus multilocularis NMDA receptor 0.0386 0.1794 0.1857
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0021 0.001 0.002
Toxoplasma gondii cathepsin CPC2 0.003 0.0055 0.0072
Echinococcus multilocularis glutamate receptor NMDA 0.0983 0.4712 0.4878
Schistosoma mansoni neuropeptide receptor 0.0243 0.1095 0.1093
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0436 0.0835
Echinococcus granulosus nmda type glutamate receptor 0.1487 0.7177 0.7429
Echinococcus granulosus casein kinase I delta 0.0024 0.0027 0.0028
Echinococcus multilocularis sterol regulatory element binding protein 0.0028 0.0047 0.0049
Brugia malayi GnHR receptor homolog 0.0031 0.0061 0.0108
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Brugia malayi Protein kinase domain containing protein 0.0037 0.009 0.0164
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.007 0.0131
Trichomonas vaginalis tubulin, putative 0.0045 0.0129 0.0527
Giardia lamblia Kinase, CMGC MAPK 0.0031 0.006 0.0281
Trypanosoma brucei unspecified product 0.0047 0.014 0.0265
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0065 0.0226 0.0433
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0041 0.0107 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0099 0.0405
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0061 0.0063
Brugia malayi beta-lactamase family protein 0.0037 0.0092 0.0168
Brugia malayi Tubulin alpha-2 chain 0.0083 0.0317 0.0598
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0052 0.0212
Leishmania major hypothetical protein, conserved 0.0066 0.0231 0.0442
Mycobacterium ulcerans hypothetical protein 0.0037 0.0092 0.0124
Trypanosoma brucei heat shock protein, putative 0.0041 0.0107 0.0203
Echinococcus multilocularis GPCR, family 2 0.0042 0.0116 0.012
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0067 0.0238 0.0246
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0092 0.0361 0.0373
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Brugia malayi Spectrin alpha chain 0.0028 0.0045 0.0078
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0028 0.0045 0.0047
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0175 0.0331
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0029 0.0049 0.0051
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0033 0.007 0.0134
Giardia lamblia DNA topoisomerase III 0.0092 0.0361 0.1811
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Echinococcus multilocularis tensin 0.0029 0.0049 0.0051
Toxoplasma gondii preprocathepsin c precursor, putative 0.0078 0.0292 0.0396
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0061 0.0063
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0052 0.0212
Loa Loa (eye worm) hypothetical protein 0.021 0.0933 0.1787
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0019 0.0002 0.0002
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0053 0.0169 0.0323
Echinococcus granulosus g-protein coupled receptor 0.0031 0.0061 0.0063
Trypanosoma cruzi heat shock protein 90, putative 0.0041 0.0107 0.0206
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0175 0.0334
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0101 0.0402 0.0542
Entamoeba histolytica acyl-CoA synthetase, putative 0.0035 0.0079 0.0252
Echinococcus granulosus Tubulin beta 2C chain 0.0045 0.0129 0.0133
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0045 0.0087
Echinococcus granulosus glutamate NMDA receptor subunit 0.1996 0.966 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0077 0.0288 0.0298
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0045 0.0087
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Echinococcus granulosus alpha tubulin 0.0083 0.0317 0.0328
Loa Loa (eye worm) doublecortin family protein 0.004 0.0105 0.0201
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0056 0.0185 0.0184
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0019 0.0002 0.0003
Schistosoma mansoni tyrosine kinase 0.0101 0.0403 0.0402
Brugia malayi STAT protein, DNA binding domain containing protein 0.0029 0.0049 0.0085
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.0016 0.003
Echinococcus multilocularis tubulin beta 1 chain 0.0045 0.0129 0.0133
Trypanosoma cruzi heat shock protein 85, putative 0.0041 0.0107 0.0206
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0029 0.0049 0.0051
Schistosoma mansoni ryanodine receptor related 0.0072 0.026 0.0258
Brugia malayi Melatonin receptor type 1A 0.0031 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.0035 0.0079 0.0152
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0092 0.0379
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0134 0.0564 0.1071
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0031 0.0056
Echinococcus multilocularis jun protein 0.006 0.0204 0.0211
Schistosoma mansoni hypothetical protein 0.0386 0.1794 0.1793
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0026 0.0035 0.0067
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0061 0.0117
Onchocerca volvulus 0.0288 0.1315 0.2517
Trypanosoma brucei beta tubulin 0.0045 0.0129 0.0243
Schistosoma mansoni hypothetical protein 0.0027 0.0042 0.004
Echinococcus multilocularis hyperpolarization activated cyclic 0.0077 0.0288 0.0298
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0201
Brugia malayi MAP kinase sur-1 0.0031 0.006 0.0106
Trichomonas vaginalis tubulin gamma chain, putative 0.0045 0.0129 0.0527
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0072 0.026 0.0269
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0061 0.0063
Echinococcus multilocularis Tubulin beta 2C chain 0.0045 0.0129 0.0133
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Loa Loa (eye worm) AUR protein kinase 0.0132 0.0553 0.1058
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0072 0.026 0.0269
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0052 0.0212
Echinococcus granulosus alpha 1A adrenergic receptor 0.0031 0.0061 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0092 0.0168
Echinococcus granulosus metabotropic glutamate receptor 2 0.0119 0.0489 0.0506
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0045 0.0087
Loa Loa (eye worm) heat shock protein 90 0.0041 0.0107 0.0206
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0072 0.026 0.0269
Echinococcus granulosus tyrosine protein kinase ABL1 0.0152 0.0654 0.0677
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0432 0.0587
Echinococcus granulosus c src tyrosine kinase 0.0067 0.0238 0.0246
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0026 0.0035 0.0064
Trypanosoma brucei acetyl-CoA carboxylase 0.0139 0.059 0.1127
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Brugia malayi hypothetical protein 0.0066 0.0231 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0162 0.0663
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0041 0.0107 0.0441
Echinococcus granulosus jun protein 0.006 0.0204 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Echinococcus multilocularis musashi 0.0057 0.019 0.0196
Schistosoma mansoni voltage-gated potassium channel 0.0117 0.048 0.0478
Brugia malayi hypothetical protein 0.0302 0.1387 0.2649
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0104
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0019 0.0005 0.0004
Mycobacterium ulcerans DNA topoisomerase I 0.0092 0.0361 0.049
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0052 0.0212
Loa Loa (eye worm) hypothetical protein 0.024 0.108 0.2067
Trichomonas vaginalis tubulin alpha chain, putative 0.0025 0.0033 0.0137
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0436 0.1789
Echinococcus granulosus suppressor of cytokine signaling 6 0.0029 0.0049 0.0051
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0066 0.023 0.0954
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0432 0.0587
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.0517 0.0989
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Echinococcus granulosus g protein coupled receptor 0.0031 0.0061 0.0063
Loa Loa (eye worm) alpha-tubulin 0.0083 0.0317 0.0606
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0072 0.026 0.0497
Leishmania major carboxylase, putative 0.0053 0.0169 0.0323
Entamoeba histolytica DNA topoisomerase III, putative 0.0092 0.0361 0.1564
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0019 0.0002 0.0003
Trichomonas vaginalis tubulin, putative 0.0025 0.0033 0.0137
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0072 0.026 0.0269
Brugia malayi hypothetical protein 0.0029 0.0049 0.0085
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.0119 0.0489 0.0936
Echinococcus granulosus peroxisome assembly protein 26 0.0083 0.0317 0.0328
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0041 0.0107 0.0206
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0386 0.1794 0.1857
Schistosoma mansoni hypothetical protein 0.003 0.0054 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0145 0.0595
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Echinococcus multilocularis NCK adaptor protein 0.0056 0.0185 0.0192
Loa Loa (eye worm) hypothetical protein 0.0056 0.0185 0.0353
Brugia malayi thymidylate synthase 0.1088 0.5224 1
Echinococcus multilocularis casein kinase I alpha 0.0024 0.0027 0.0028
Entamoeba histolytica heat shock protein 90, putative 0.0041 0.0107 0.0383
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0028 0.0045 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0016 0.0064
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0028 0.0045 0.0047
Echinococcus granulosus hypothetical protein 0.0029 0.0049 0.0051
Loa Loa (eye worm) latrophilin receptor protein 2 0.0042 0.0116 0.0223
Echinococcus granulosus 7tm_1 domain containing protein 0.0031 0.0061 0.0063
Trichomonas vaginalis heat shock protein, putative 0.0041 0.0107 0.0441
Onchocerca volvulus 0.0029 0.0049 0.0094
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0061 0.0114
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0031 0.0061 0.0108
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.003 0.0054 0.0055
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.007
Entamoeba histolytica hypothetical protein 0.0121 0.0499 0.2208
Echinococcus granulosus tyrosine protein kinase shark 0.0043 0.0122 0.0126
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0072 0.026 0.0258
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0462 0.2169 0.4151
Echinococcus granulosus thymidylate synthase 0.1088 0.5224 0.5408
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0087
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0041 0.0107 0.0144
Leishmania major casein kinase, putative 0.0024 0.0027 0.0052
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.019 0.0355
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0072 0.026 0.0269
Loa Loa (eye worm) STAT protein 0.0029 0.0049 0.0094
Loa Loa (eye worm) tubulin beta chain 0.0045 0.0129 0.0246
Entamoeba histolytica tubulin alpha-1 chain 0.0083 0.0317 0.1359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0122 0.05
Entamoeba histolytica protein kinase, putative 0.0028 0.0045 0.0094
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0092 0.0379
Loa Loa (eye worm) glutamate receptor 0.0119 0.0489 0.0936
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Echinococcus multilocularis orexin receptor type 2 0.0031 0.0061 0.0063
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Echinococcus granulosus hypothetical protein 0.0072 0.026 0.0269
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0079 0.0106
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0072 0.026 0.0489
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Trypanosoma cruzi DNA topoisomerase III, putative 0.0092 0.0361 0.069
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0065 0.0226 0.0938
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0061 0.0063
Onchocerca volvulus 0.0031 0.0061 0.0117
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Echinococcus granulosus Spectrin alpha actinin 0.0028 0.0045 0.0047
Schistosoma mansoni voltage-gated potassium channel 0.0117 0.048 0.0478
Echinococcus granulosus allatostatin A receptor 0.0031 0.0061 0.0063
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0061 0.006
Echinococcus granulosus G protein coupled receptor 139 0.0031 0.0061 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0085
Mycobacterium ulcerans beta-lactamase 0.0037 0.0092 0.0124
Chlamydia trachomatis glutamine binding protein 0.0119 0.0489 0.0665
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.0102 0.0195
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0436 0.0835
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.009
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0077 0.0288 0.0286
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0105 0.0109
Loa Loa (eye worm) voltage-dependent calcium channel 0.0072 0.026 0.0497
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Onchocerca volvulus 0.0031 0.0061 0.0117
Trypanosoma cruzi casein kinase, putative 0.0024 0.0027 0.0052
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.006 0.0105
Schistosoma mansoni tyrosine kinase 0.0124 0.0515 0.0513
Onchocerca volvulus 0.0028 0.0045 0.0087
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0031 0.0061 0.0063
Loa Loa (eye worm) hypothetical protein 0.0119 0.0489 0.0936
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0072 0.026 0.0258
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0092 0.0361 0.0359
Plasmodium falciparum ataxin-2 like protein, putative 0.0066 0.0231 0.0309
Schistosoma mansoni tyrosine kinase 0.0067 0.0238 0.0236
Schistosoma mansoni heat shock protein 0.0041 0.0107 0.0106
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0072 0.026 0.0352
Loa Loa (eye worm) hypothetical protein 0.0038 0.0097 0.0186
Trypanosoma brucei trypanothione reductase 0.0047 0.0139 0.0262
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0031 0.0061 0.006
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0201 0.0208
Mycobacterium ulcerans two component sensor kinase MprB 0.0041 0.0107 0.0144
Trichomonas vaginalis tubulin beta chain, putative 0.0025 0.0033 0.0137
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0072 0.026 0.0269
Echinococcus granulosus sodium leak channel non selective protein 0.0072 0.026 0.0269
Mycobacterium tuberculosis Probable two component sensor kinase 0.0041 0.0107 0.0144
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0026 0.0036 0.0047
Plasmodium falciparum heat shock protein 90 0.0041 0.0107 0.014
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0042 0.0116 0.012
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0029 0.0049 0.0094
Echinococcus granulosus Niemann Pick C1 protein 0.0094 0.0367 0.038
Schistosoma mansoni tensin 0.0029 0.0049 0.0047
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0052 0.0163 0.0311
Onchocerca volvulus 0.0029 0.0049 0.0094
Loa Loa (eye worm) tubulin beta-1 chain 0.0045 0.0129 0.0246
Plasmodium falciparum ataxin-2 like protein, putative 0.0066 0.0231 0.0309
Giardia lamblia DINP protein human, muc B family 0.0033 0.007 0.0332
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0088 0.0165
Echinococcus multilocularis casein kinase I delta 0.0024 0.0027 0.0028
Echinococcus multilocularis expressed conserved protein 0.0062 0.021 0.0218
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.1082 0.5197 0.538
Plasmodium falciparum acyl-CoA synthetase 0.0026 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.0195
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0067 0.0238 0.0246
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0132 0.0553 0.0748
Schistosoma mansoni hypothetical protein 0.0062 0.0211 0.0209
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0061 0.0063
Brugia malayi Tubulin alpha chain 0.0083 0.0317 0.0598
Echinococcus granulosus dro:myosuppressin receptor 0.0031 0.0061 0.0063
Echinococcus multilocularis potassium voltage gated channel protein 0.0072 0.026 0.0269
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0031 0.0061 0.0063
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0019 0.0005 0.0019
Loa Loa (eye worm) hypothetical protein 0.0119 0.0489 0.0936
Brugia malayi Glutamate receptor 1 precursor 0.0964 0.4617 0.8837
Schistosoma mansoni tubulin subunit beta 0.0045 0.0129 0.0127
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0031 0.0061 0.0117
Entamoeba histolytica hypothetical protein 0.0121 0.0499 0.2208
Schistosoma mansoni protein kinase 0.0024 0.0027 0.0026
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.0308 0.0306
Onchocerca volvulus 0.007 0.0251 0.0481
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0031 0.0059 0.0158
Brugia malayi heat shock protein 90 0.0041 0.0107 0.0197
Echinococcus multilocularis beta tubulin 0.0045 0.0129 0.0133
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Echinococcus multilocularis protein dispatched 1 0.0032 0.0066 0.0069
Echinococcus granulosus tyrosine protein kinase Fyn 0.0067 0.0238 0.0246
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0033 0.007 0.0093
Echinococcus multilocularis Tubulin alpha 1 chain 0.0083 0.0317 0.0328
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0028 0.0045 0.0186
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0436 0.0589
Schistosoma mansoni acetyl-CoA carboxylase 0.0139 0.059 0.0589
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0053 0.0169 0.0167
Leishmania major hypothetical protein, conserved 0.0072 0.026 0.0497
Echinococcus multilocularis SH2 motif 0.0029 0.0049 0.0051
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0041 0.0107 0.0144
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0436 0.1789
Brugia malayi larval opioid receptor 0.0031 0.0061 0.0108
Schistosoma mansoni tensin 0.0029 0.0049 0.0047
Echinococcus granulosus Tubulin beta 2C chain 0.0045 0.0129 0.0133
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0072 0.026 0.0258
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Trypanosoma brucei DNA topoisomerase ii 0.0579 0.2738 0.5239
Schistosoma mansoni voltage-gated cation channel 0.0072 0.026 0.0258
Echinococcus multilocularis transient receptor potential cation channel 0.0072 0.026 0.0269
Echinococcus multilocularis c src tyrosine kinase 0.0067 0.0238 0.0246
Plasmodium falciparum alpha tubulin 2 0.0083 0.0317 0.0426
Loa Loa (eye worm) DNA topoisomerase III 0.0092 0.0361 0.069
Echinococcus granulosus sex peptide receptor 0.0031 0.0061 0.0063
Leishmania major 4-coumarate:coa ligase-like protein 0.0035 0.0079 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0081 0.033
Brugia malayi casein kinase 1, delta 0.0024 0.0027 0.0043
Onchocerca volvulus 0.0031 0.0061 0.0117
Trichomonas vaginalis AGC family protein kinase 0.0132 0.0553 0.2267
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0119 0.0489 0.0661
Chlamydia trachomatis DNA gyrase subunit A 0.152 0.7334 1
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0052 0.0163 0.0311
Echinococcus multilocularis sex peptide receptor 0.0031 0.0061 0.0063
Schistosoma mansoni tensin 0.0029 0.0049 0.0047
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0072 0.026 0.0258
Loa Loa (eye worm) hypothetical protein 0.0119 0.0489 0.0936
Loa Loa (eye worm) hypothetical protein 0.0066 0.023 0.044
Brugia malayi kinase, mitochondrial precursor 0.0041 0.0107 0.0197
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1289 0.5287
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0063 0.0215 0.0223
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0119 0.0489 0.0936
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0102 0.0105
Mycobacterium tuberculosis Conserved protein 0.0037 0.0092 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0162 0.0663
Echinococcus multilocularis tubulin delta chain 0.0019 0.0005 0.0005
Trichomonas vaginalis tubulin beta chain, putative 0.0083 0.0317 0.1299
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.019 0.0197
Leishmania major hypothetical protein, conserved 0.0041 0.0107 0.0206
Schistosoma mansoni endoplasmin 0.0041 0.0107 0.0106
Trypanosoma cruzi casein kinase, putative 0.0024 0.0027 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0061 0.006
Entamoeba histolytica heat shock protein 90, putative 0.0041 0.0107 0.0383
Trichomonas vaginalis receptor histidine kinase, putative 0.0041 0.0107 0.0441
Echinococcus granulosus potassium voltage gated channel protein 0.0072 0.026 0.0269
Echinococcus granulosus short transient receptor potential channel 6 0.0072 0.026 0.0269
Brugia malayi Protein kinase domain containing protein 0.0039 0.0102 0.0186
Echinococcus multilocularis Tubulin alpha 1 chain 0.0083 0.0317 0.0328
Brugia malayi Latrophilin receptor protein 2 0.0042 0.0116 0.0214
Brugia malayi polk-prov protein 0.0037 0.0088 0.016
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.005 0.0155 0.0297
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0031 0.0061 0.0108
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0072 0.026 0.0497
Echinococcus granulosus tubulin alpha 3 chain 0.0083 0.0317 0.0328
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0052 0.0163 0.0309
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0031 0.0061 0.006
Onchocerca volvulus 0.0031 0.0061 0.0117
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0061 0.0109
Entamoeba histolytica protein kinase, putative 0.0031 0.0059 0.0158
Plasmodium falciparum alpha tubulin 1 0.0083 0.0317 0.0426
Leishmania major developmentally regulated phosphoprotein-like protein 0.0041 0.0107 0.0206
Brugia malayi SH2 domain containing protein 0.0029 0.0049 0.0085
Echinococcus multilocularis Tubulin alpha 1 chain 0.0083 0.0317 0.0328
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.1082 0.5197 0.538
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Brugia malayi beta-lactamase family protein 0.0037 0.0092 0.0168
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0504 0.2374 0.2457
Mycobacterium tuberculosis Conserved protein 0.0037 0.0092 0.0124
Brugia malayi DNA topoisomerase III beta-1 0.0092 0.0361 0.0682
Onchocerca volvulus 0.0129 0.0542 0.1037
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0061 0.0063
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Echinococcus multilocularis survival motor neuron protein 1 0.0302 0.1387 0.1436
Trypanosoma cruzi DNA topoisomerase II, putative 0.037 0.1717 0.3287
Entamoeba histolytica hypothetical protein 0.0028 0.0045 0.0094
Echinococcus granulosus nostrin 0.0028 0.0045 0.0047
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0053 0.0169 0.0228
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0061 0.0063
Schistosoma mansoni glutamate receptor kainate 0.0964 0.4617 0.4616
Loa Loa (eye worm) hypothetical protein 0.0077 0.0288 0.0551
Leishmania major mitochondrial DNA topoisomerase II 0.0579 0.2738 0.5241
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0092 0.0091
Loa Loa (eye worm) tubulin alpha-3 chain 0.0058 0.0193 0.0369
Echinococcus granulosus histone acetyltransferase KAT2B 0.0158 0.0681 0.0705
Loa Loa (eye worm) hypothetical protein 0.0039 0.0101 0.0194
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0031 0.006 0.0114
Onchocerca volvulus 0.004 0.0105 0.0201
Schistosoma mansoni tubulin subunit beta 0.0045 0.0129 0.0127
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0175 0.0331
Echinococcus multilocularis mitogen activated protein kinase 0.0031 0.006 0.0062
Brugia malayi MH2 domain containing protein 0.0124 0.0517 0.0981
Giardia lamblia DNA topoisomerase III 0.0092 0.0361 0.1811
Brugia malayi ion channel NompC 0.0072 0.026 0.0489
Echinococcus granulosus hyperpolarization activated cyclic 0.0077 0.0288 0.0298
Brugia malayi phosphofructokinase 0.0108 0.0436 0.0827
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0029 0.0049 0.0051
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0031 0.0061 0.0063
Loa Loa (eye worm) hypothetical protein 0.0034 0.0078 0.0149
Brugia malayi Niemann-Pick C1 protein precursor 0.0066 0.023 0.0432
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0072 0.026 0.0494
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0066 0.0233 0.0232
Echinococcus granulosus fch and double sh3 domains protein 2 0.0028 0.0045 0.0047
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0042 0.0116 0.012
Echinococcus granulosus potassium large conductance calcium activated 0.0072 0.026 0.0269
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0041 0.0107 0.0206
Schistosoma mansoni glutamate receptor AMPA 0.0964 0.4617 0.4616
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0436 0.0835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0162 0.0663
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0045 0.0186
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0072 0.026 0.0269
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0139 0.0183
Giardia lamblia Aurora kinase 0.0132 0.0553 0.2788
Echinococcus multilocularis geminin 0.0545 0.2573 0.2663
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0024 0.0027 0.0052
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0067 0.0238 0.0246
Brugia malayi hypothetical protein 0.024 0.108 0.206
Toxoplasma gondii MAPEG family protein 0.0063 0.0216 0.0292
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0028 0.0045 0.0087
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0039 0.0102 0.0105
Brugia malayi casein kinase I 0.0024 0.0027 0.0043
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0143 0.0586
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.1088 0.5224 0.7122
Loa Loa (eye worm) SRC-1 0.0067 0.0238 0.0456
Trypanosoma cruzi DNA polymerase kappa, putative 0.0054 0.0175 0.0334
Leishmania major alpha tubulin 0.0083 0.0317 0.0606
Loa Loa (eye worm) tubulin alpha-2 chain 0.0083 0.0317 0.0606
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0045 0.0129 0.0133
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0041 0.0107 0.0144
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0052 0.0064
Brugia malayi Receptor family ligand binding region containing protein 0.0129 0.0542 0.103
Echinococcus granulosus tubulin alpha 0.0045 0.0129 0.0133
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0061 0.0081
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0064 0.0221 0.0424
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0092 0.0124
Mycobacterium ulcerans DNA gyrase subunit A 0.152 0.7334 1
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0462 0.2169 0.2245
Echinococcus granulosus endophilin A3 0.0028 0.0045 0.0047
Loa Loa (eye worm) thyroid receptor interactor 0.0028 0.0045 0.0087
Entamoeba histolytica protein kinase, putative 0.0132 0.0553 0.246
Plasmodium vivax DNA gyrase subunit B, putative 0.0964 0.4618 0.6295
Loa Loa (eye worm) hypothetical protein 0.0042 0.0116 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0097 0.0398
Echinococcus granulosus Tubulin alpha 1 chain 0.0083 0.0317 0.0328
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0028 0.0045 0.0047
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0119 0.0489 0.0928
Onchocerca volvulus 0.0031 0.0061 0.0117
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0386 0.1794 0.1857
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0077 0.0288 0.0286
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1289 0.5287
Loa Loa (eye worm) hypothetical protein 0.0092 0.0357 0.0683
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0092 0.0174
Echinococcus multilocularis nmda type glutamate receptor 0.1102 0.5292 0.5478
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0031 0.0061 0.0063
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0021 0.001 0.002
Schistosoma mansoni 60S ribosomal protein L21 0.0076 0.0279 0.0278
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0063 0.0216 0.0223
Schistosoma mansoni hypothetical protein 0.0027 0.0042 0.004
Echinococcus granulosus casein kinase I delta 0.0024 0.0027 0.0028
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0061 0.006
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0031 0.006 0.0079
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0119 0.0489 0.0665
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.1082 0.5197 0.538
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0072 0.026 0.0269
Loa Loa (eye worm) tubulin alpha chain 0.0083 0.0317 0.0606
Echinococcus multilocularis neuropeptide s receptor 0.0031 0.0061 0.0063
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0092 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0072 0.026 0.0258
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0072 0.026 0.0489
Leishmania major heat shock protein 83-1 0.0041 0.0107 0.0206
Brugia malayi RhoGAP domain containing protein 0.0029 0.0049 0.0085
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0041 0.0107 0.0441
Echinococcus granulosus NCK adaptor protein 0.0056 0.0185 0.0192
Echinococcus granulosus expressed protein 0.0028 0.0045 0.0047
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0053 0.0169 0.032
Trichomonas vaginalis endoplasmin, putative 0.0041 0.0107 0.0441
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0031 0.0061 0.0117
Schistosoma mansoni pyruvate dehydrogenase 0.0041 0.0107 0.0106
Echinococcus granulosus tensin 0.0029 0.0049 0.0051
Plasmodium vivax endoplasmin, putative 0.0041 0.0107 0.014
Schistosoma mansoni hypothetical protein 0.0042 0.0116 0.0115
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0436 0.0835
Trypanosoma brucei casein kinase I, isoform 2 0.0024 0.0027 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0061 0.006
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0072 0.026 0.0269
Giardia lamblia Dipeptidyl-peptidase I precursor 0.003 0.0055 0.0255
Entamoeba histolytica hypothetical protein 0.0028 0.0045 0.0094
Brugia malayi Probable DNA topoisomerase II 0.0462 0.2169 0.4146
Trypanosoma cruzi target of rapamycin kinase 3 0.0052 0.0162 0.031
Schistosoma mansoni integrin alpha 0.002 0.0009 0.0008
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0072 0.026 0.0269
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0031 0.006 0.0114
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0031 0.0061 0.0063
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0436 0.0452
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0092 0.0124
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0056 0.0185 0.0354
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.0139 0.059 0.0611
Plasmodium vivax casein kinase 1, putative 0.0024 0.0027 0.0031
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0041 0.0107 0.0111
Loa Loa (eye worm) intermediate filament protein 0.0057 0.019 0.0363
Schistosoma mansoni eps8-related protein 0.0028 0.0045 0.0044
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0052 0.0163 0.0311
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0143 0.0148
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0045 0.0078
Onchocerca volvulus 0.0031 0.0061 0.0117
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0061 0.0063
Trichomonas vaginalis DNA polymerase eta, putative 0.0054 0.0175 0.0717
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0162 0.0663
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0116 0.0478 0.0916
Echinococcus multilocularis serotonin receptor 0.0031 0.0061 0.0063
Brugia malayi Dopamine receptor protein 1 0.0031 0.0061 0.0108
Echinococcus multilocularis RUN 0.004 0.0105 0.0109
Echinococcus granulosus Tubulin alpha 1 chain 0.0083 0.0317 0.0328
Onchocerca volvulus 0.0039 0.0102 0.0195
Brugia malayi RE15519p 0.0031 0.0061 0.0108
Brugia malayi PAS domain containing protein 0.0071 0.0258 0.0486
Echinococcus granulosus Tubulin beta 2C chain 0.0045 0.0129 0.0133
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0061 0.006
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0092 0.0361 0.069
Leishmania major DNA topoisomerase III, putative 0.0092 0.0361 0.069
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0022 0.0016 0.0027
Trypanosoma cruzi tubulin gamma chain 0.0045 0.0129 0.0246
Loa Loa (eye worm) hypothetical protein 0.0134 0.0564 0.1079
Loa Loa (eye worm) hypothetical protein 0.0302 0.1387 0.2655
Loa Loa (eye worm) AUR protein kinase 0.0132 0.0553 0.1058
Trypanosoma brucei heat shock protein 90, putative 0.0041 0.0107 0.0203
Trypanosoma brucei zeta tubulin 0.0019 0.0005 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0079 0.0143
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0022 0.0016 0.0016
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0041 0.0107 0.0144
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0087
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0041 0.0107 0.0144
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0065 0.0226 0.0433
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1577 0.7617 0.7884
Loa Loa (eye worm) ryanodine receptor 0.0072 0.026 0.0497
Brugia malayi hypothetical protein 0.0031 0.0061 0.0108
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Giardia lamblia GTOR 0.0065 0.0226 0.1128
Onchocerca volvulus 0.0092 0.0361 0.069
Echinococcus granulosus calcium activated potassium channel 0.0074 0.027 0.028
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.003 0.0054 0.0055
Brugia malayi Doublecortin family protein 0.004 0.0105 0.0193
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0031 0.006 0.0114
Schistosoma mansoni hypothetical protein 0.0031 0.0061 0.006
Leishmania major hypothetical protein, conserved 0.0028 0.0045 0.0087
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0052 0.0162 0.031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0097 0.0398
Trichomonas vaginalis tubulin alpha chain, putative 0.0045 0.0129 0.0527
Echinococcus granulosus voltage gated potassium channel 0.0072 0.026 0.0269
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0072 0.026 0.0489
Brugia malayi Tyrosine-protein kinase abl-1 0.011 0.0449 0.0852
Schistosoma mansoni adapter molecule crk 0.0056 0.0185 0.0184
Echinococcus multilocularis tubulin alpha chain 0.0083 0.0317 0.0328
Trypanosoma cruzi casein kinase, putative 0.0024 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0061 0.0117
Plasmodium vivax SET domain protein, putative 0.006 0.0201 0.0268
Entamoeba histolytica tubulin family protein 0.0045 0.0129 0.0481
Echinococcus multilocularis sodium leak channel non selective protein 0.0072 0.026 0.0269
Loa Loa (eye worm) hypothetical protein 0.0072 0.026 0.0497
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0022 0.0016 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0045 0.0186
Trypanosoma brucei alpha tubulin, putative 0.0025 0.0033 0.0061
Schistosoma mansoni loxhd1 0.004 0.0105 0.0104
Schistosoma mansoni run and tbc1 domain containing 0.0028 0.0045 0.0044
Leishmania major beta tubulin 0.0045 0.0129 0.0246
Chlamydia trachomatis biotin carboxylase 0.0048 0.0145 0.0195
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.037 0.1717 0.3285
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0065 0.0226 0.0433
Brugia malayi Tensin 0.0029 0.0049 0.0085
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0052 0.0212
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0025 0.0033 0.0137
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0077 0.0288 0.0286
Echinococcus granulosus tubulin alpha chain 0.0083 0.0317 0.0328
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0065 0.0226 0.0433
Brugia malayi neuropeptide F receptor 0.0031 0.0061 0.0108
Brugia malayi beta-tubulin, identical 0.0045 0.0129 0.0238
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0028 0.0045 0.0047
Entamoeba histolytica casein kinase, putative 0.0024 0.0027 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0094
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0029 0.0049 0.0047
Echinococcus granulosus Protein patched homolog 1 0.0028 0.0047 0.0049
Brugia malayi latrophilin 2 splice variant baaae 0.0092 0.0357 0.0675
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0174 0.0762 0.0789
Echinococcus multilocularis casein kinase i 0.0024 0.0027 0.0028
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0052 0.0068
Echinococcus granulosus heat shock protein 0.0041 0.0107 0.0111
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0061 0.006
Schistosoma mansoni ATP-binding cassette transporter 0.0964 0.4617 0.4616
Loa Loa (eye worm) p53BP2 0.0028 0.0045 0.0087
Plasmodium vivax tubulin epsilon chain, putative 0.0045 0.0129 0.0169

Activities

Activity type Activity value Assay description Source Reference
AUC (ADMET) = 23.2 ug ml-1 hr-1 AUC (0-4 hr) ug/ml/h ChEMBL. 7990118
ED50 (functional) = 3.1 mg kg-1 Evaluation of efficacy on systemic infections Escherichia coli HM-42, after oral administration in mice ChEMBL. 7990118
ED50 (functional) = 3.1 mg kg-1 Evaluation of efficacy on systemic infections Escherichia coli HM-42, after oral administration in mice ChEMBL. 7990118
ED50 (functional) = 17.9 mg kg-1 Evaluation of efficacy on systemic infections Staphylococcus aureus HS-93,after oral administration in mice ChEMBL. 7990118
ED50 (functional) = 17.9 mg kg-1 Evaluation of efficacy on systemic infections Staphylococcus aureus HS-93,after oral administration in mice ChEMBL. 7990118
ED50 (functional) = 163.9 mg kg-1 Evaluation of efficacy on systemic infections Pseudomonas aeruginosa HS-116, after oral administration in mice ChEMBL. 7990118
ED50 (functional) = 163.9 mg kg-1 Evaluation of efficacy on systemic infections Pseudomonas aeruginosa HS-116, after oral administration in mice ChEMBL. 7990118
Log k' (ADMET) = 0.7694 HPLC capacity factor (k') ChEMBL. 7990118
MIC (functional) = 0.015 ug ml-1 In vitro minimum inhibitory concentration for Bacillus subtilis ATCC 6633 ChEMBL. 7990118
MIC (functional) = 0.06 ug ml-1 In vitro minimum inhibitory concentration for Staphylococcus epidermidis ATCC 155-1 ChEMBL. 7990118
MIC (functional) = 0.06 ug ml-1 In vitro minimum inhibitory concentration to inhibit Klebsiella pneumoniae ATCC 10031 ChEMBL. 7990118
MIC (functional) = 0.12 ug ml-1 In vitro minimum inhibitory concentration for Staphylococcus aureus ATCC 25178 ChEMBL. 7990118
MIC (functional) = 0.12 ug ml-1 In vitro minimum inhibitory concentration for Enterobacter cloacae ATCC 23355 ChEMBL. 7990118
MIC (functional) = 0.25 ug ml-1 In vitro minimum inhibitory concentration for Morganella morganii ATCC 8019 ChEMBL. 7990118
MIC (functional) = 0.25 ug ml-1 In vitro minimum inhibitory concentration for Proteus vulgaris ATCC 8427 ChEMBL. 7990118
MIC (functional) = 0.25 ug ml-1 In vitro minimum inhibitory concentration for Escherichia coli ATCC 10799 ChEMBL. 7990118
MIC (functional) = 0.25 ug ml-1 In vitro minimum inhibitory concentration for Escherichia coli ATCC 10799 ChEMBL. 7990118
MIC (functional) = 1 ug ml-1 In vitro minimum inhibitory concentration for Bacillus cereus ATCC 11778 ChEMBL. 7990118
MIC (functional) = 1 ug ml-1 In vitro minimum inhibitory concentration for Streptococcus faecalis ATCC 10541 ChEMBL. 7990118
MIC (functional) = 2 ug ml-1 In vitro minimum inhibitory concentration for Pseudomonas aeruginosa ATCC 10145 ChEMBL. 7990118
pKa1 = 6.08 Measured ionization constant (pKa) ChEMBL. 7990118
pKa2 = 8.2 Dissociation constant (pKa) ChEMBL. 7990118
S = 97.1 ug ml-1 Solubility (buffer pH 7.4) ChEMBL. 7990118

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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