Detailed information for compound 283235

Basic information

Technical information
  • TDR Targets ID: 283235
  • Name: 1-methyl-5-phenyl-3H-benzo[h][1,4]benzodiazep in-2-one
  • MW: 300.354 | Formula: C20H16N2O
  • H donors: 0 H acceptors: 1 LogP: 3.85 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1C(=O)CN=C(c2c1cc1ccccc1c2)c1ccccc1
  • InChi: 1S/C20H16N2O/c1-22-18-12-16-10-6-5-9-15(16)11-17(18)20(21-13-19(22)23)14-7-3-2-4-8-14/h2-12H,13H2,1H3
  • InChiKey: AJHPSUZJBIEASQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus GABA-A receptor; anion channel Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni Cys-loop ligand gated ion channel subunit GABA-A receptor; anion channel   467 aa 479 aa 29.2 %
Echinococcus granulosus glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 439 aa 29.6 %
Echinococcus granulosus glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 441 aa 33.8 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 468 aa 28.6 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 494 aa 25.5 %
Onchocerca volvulus Large subunit GTPase 1 homolog GABA-A receptor; anion channel   467 aa 496 aa 26.0 %
Onchocerca volvulus Gamma-aminobutyric acid receptor subunit beta homolog GABA-A receptor; anion channel   467 aa 433 aa 34.6 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 446 aa 29.1 %
Echinococcus multilocularis glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 478 aa 28.7 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 434 aa 26.7 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog GABA-A receptor; anion channel   467 aa 418 aa 19.6 %
Brugia malayi Cation transporter family protein GABA-A receptor; anion channel   467 aa 453 aa 28.5 %
Echinococcus multilocularis glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 446 aa 28.0 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 435 aa 29.7 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 375 aa 21.9 %
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative GABA-A receptor; anion channel   467 aa 384 aa 19.5 %
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit GABA-A receptor; anion channel   467 aa 379 aa 19.3 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 454 aa 29.5 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 454 aa 30.4 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 461 aa 27.8 %
Onchocerca volvulus Eukaryotic initiation factor 4A-III homolog GABA-A receptor; anion channel   467 aa 453 aa 26.9 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 447 aa 25.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi nuclear receptor RXR 0.0012 0.0003 0.0003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.019 0.0362 0.0665
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.02 0.5312
Loa Loa (eye worm) nuclear hormone receptor 0.0012 0.0003 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.005 0.008 0.008
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0016 0.0027
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.018 0.0342 0.0342
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0031 0.0031
Echinococcus multilocularis somatostatin receptor 0.018 0.0342 0.0342
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0026 0.0026
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0017 0.0442
Echinococcus multilocularis fmrfamide receptor 0.018 0.0342 0.0342
Echinococcus granulosus G protein coupled receptor 139 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0025 0.0025
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0023 0.0025 0.0025
Echinococcus multilocularis carboxylesterase 5A 0.0139 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni nuclear receptor 0.0012 0.0003 0.0003
Echinococcus multilocularis neuropeptides capa receptor 0.018 0.0342 0.0342
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0017 0.0059
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0051 0.0081 0.2213
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.005 0.0081 0.1357
Brugia malayi F/Y-rich N-terminus family protein 0.0014 0.0006 0.0006
Echinococcus granulosus neuropeptides capa receptor 0.018 0.0342 0.0342
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0017 0.0017
Mycobacterium ulcerans NADH dehydrogenase 0.005 0.0081 0.1838
Loa Loa (eye worm) hypothetical protein 0.0108 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Brugia malayi ecdysone receptor 0.0012 0.0003 0.0003
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0025 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.018 0.0342 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0217 0.5978
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0006 0.0006
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0118 0.0217 0.0217
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0032 0.0032
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0052 0.1408
Schistosoma mansoni hypothetical protein 0.0413 0.0812 0.0812
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0851 0.1695 0.1695
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus multilocularis neuropeptide receptor A26 0.018 0.0342 0.0342
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0969 0.1933 0.1933
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0084 0.0153
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.005 0.0081 0.1682
Echinococcus granulosus methyl CpG binding domain protein 2 0.0034 0.0047 0.0047
Echinococcus granulosus sulfide:quinone oxidoreductase 0.005 0.0081 0.0081
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0031 0.0031
Echinococcus multilocularis g protein coupled receptor 0.018 0.0342 0.0342
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0032 0.013
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0026 0.0032 0.0032
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.018 0.0342 0.0342
Brugia malayi hypothetical protein 0.0119 0.0219 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0031 0.0031
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0052 0.1408
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus multilocularis nAChR subunit 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Schistosoma mansoni nAChR subunit 0.0023 0.0025 0.0025
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0118 0.0217 0.0217
Trichomonas vaginalis apoptosis inducing factor, putative 0.005 0.0081 0.2198
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.005 0.0081 0.0081
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.02 0.0367
Trypanosoma brucei NADH dehydrogenase 0.005 0.0081 0.0146
Brugia malayi steroid hormone receptor 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0051 0.0081 0.0081
Leishmania major hypothetical protein, conserved 0.005 0.0081 0.0146
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.018 0.0342 0.0342
Mycobacterium ulcerans lipase LipD 0.0144 0.0269 0.7294
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0006 0.0009
Schistosoma mansoni SET domain protein 0.0029 0.0037 0.0037
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.005 0.0081 0.0081
Onchocerca volvulus Putative nachr subunit 0.0023 0.0025 0.0025
Echinococcus granulosus thyroid hormone receptor alpha 0.0012 0.0003 0.0003
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0032 0.0032
Echinococcus multilocularis neuropeptide receptor 0.018 0.0342 0.0342
Schistosoma mansoni biogenic amine receptor 0.018 0.0342 0.0342
Echinococcus granulosus geminin 0.0173 0.0328 0.0328
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0016 0.0027
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0031 0.0031
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0025 0.0025
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0144 0.0269 0.0269
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0119 0.0219 0.0219
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0144 0.0269 0.0269
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.018 0.0342 0.0342
Schistosoma mansoni sex comb on midleg homolog 0.0095 0.017 0.017
Toxoplasma gondii NADPH-glutathione reductase 0.019 0.0362 0.1844
Trypanosoma cruzi hypothetical protein, conserved 0.0144 0.0269 0.0493
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0109 0.2984
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.02 0.5519
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0732
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0035 0.0035
Schistosoma mansoni phd finger protein 0.0013 0.0005 0.0005
Plasmodium vivax phosphodiesterase gamma, putative 0.0118 0.0217 0.4777
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0498 0.0984 0.1813
Brugia malayi glutathione reductase 0.0232 0.0447 0.0447
Loa Loa (eye worm) hypothetical protein 0.0119 0.0219 0.0219
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.018 0.0342 0.0342
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.018 0.0342 0.0342
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0969 0.1933 1
Schistosoma mansoni smad 0.0016 0.0012 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.018 0.0342 0.0342
Brugia malayi mbt repeat family protein 0.0095 0.017 0.017
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.005 0.0081 0.0406
Brugia malayi nuclear receptor NHR-88 0.0026 0.0031 0.0031
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.005 0.0081 0.1838
Schistosoma mansoni rab6-interacting 0.002 0.002 0.002
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.02 0.0367
Mycobacterium ulcerans monoxygenase 0.005 0.0081 0.1838
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0014 0.0007 0.001
Brugia malayi hypothetical protein 0.0012 0.0003 0.0003
Schistosoma mansoni nAChR subunit 0.0023 0.0025 0.0025
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0007 0.001
Echinococcus granulosus neuropeptide receptor 0.018 0.0342 0.0342
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0851 0.1695 0.1695
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0144 0.0269 0.1438
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0109 0.2984
Echinococcus granulosus thyrotropin releasing hormone receptor 0.044 0.0867 0.0867
Schistosoma mansoni intermediate filament proteins 0.0028 0.0035 0.0035
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.005 0.0081 0.0146
Schistosoma mansoni coup transcription factor 0.0026 0.0031 0.0031
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.044 0.0867 0.0867
Schistosoma mansoni rhodopsin-like orphan GPCR 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Echinococcus granulosus allatostatin A receptor 0.018 0.0342 0.0342
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0052 0.1408
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0012 0.0012
Echinococcus multilocularis fmrfamide receptor 0.018 0.0342 0.0342
Echinococcus granulosus glutamate synthase 0.005 0.0081 0.0081
Echinococcus granulosus histone deacetylase 0.0018 0.0016 0.0016
Schistosoma mansoni zinc finger protein 0.0012 0.0003 0.0003
Trypanosoma brucei Aminopeptidase M1, putative 0.0144 0.0269 0.0495
Echinococcus multilocularis glycine receptor subunit beta 0.0023 0.0025 0.0025
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0144 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Plasmodium falciparum transporter, putative 0.0026 0.0032 0.057
Echinococcus multilocularis nAChR subunit 0.0012 0.0004 0.0004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Echinococcus multilocularis rhodopsin orphan GPCR 0.018 0.0342 0.0342
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.012 0.0221 0.0221
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0144 0.0269 0.0269
Trypanosoma brucei glucosidase, putative 0.0036 0.0052 0.0094
Brugia malayi sulfakinin receptor protein 0.018 0.0342 0.0342
Echinococcus granulosus rhodopsin orphan GPCR 0.018 0.0342 0.0342
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.005 0.0081 0.1838
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0118 0.0217 0.0217
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.005 0.0081 0.1838
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0006 0.0135
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0144 0.0269 0.0269
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0025 0.0025
Brugia malayi Tachykinin-like peptides receptor 99D 0.018 0.0342 0.0342
Echinococcus granulosus acetylcholinesterase 0.0139 0.0258 0.0258
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0144 0.0269 0.0269
Onchocerca volvulus 0.0026 0.0032 0.0032
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0006 0.0135
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0051 0.0081 0.0147
Echinococcus granulosus peregrin 0.0013 0.0005 0.0005
Echinococcus granulosus neuropeptides capa receptor 0.018 0.0342 0.0342
Echinococcus multilocularis sex peptide receptor 0.018 0.0342 0.0342
Brugia malayi Carboxylesterase family protein 0.0139 0.0258 0.0258
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0222 0.0222
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0031 0.0031
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.005 0.0081 0.0406
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Trichomonas vaginalis glutathione reductase, putative 0.019 0.0362 1
Trypanosoma cruzi hypothetical protein, conserved 0.0118 0.0217 0.0398
Trypanosoma brucei ISWI complex protein 0.003 0.004 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.018 0.0342 0.0342
Brugia malayi nuclear receptor NHR-88 0.0012 0.0003 0.0003
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.0308 0.0308
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0032 0.0032
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0023 0.0025 0.0025
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0026 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0081 0.0146
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0109 0.2984
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Echinococcus granulosus histone deacetylase 8 0.0018 0.0016 0.0016
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0969 0.1933 0.1933
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.005 0.0081 0.0146
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.018 0.0342 0.0342
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0219 0.5841
Schistosoma mansoni opsin-like receptor 0.018 0.0342 0.0342
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.4777
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0031 0.0031
Echinococcus granulosus dnaJ subfamily B 0.0413 0.0812 0.0812
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0118 0.0217 0.0398
Echinococcus multilocularis beta LACTamase domain containing family member 0.0144 0.0269 0.0269
Schistosoma mansoni histone deacetylase 0.0064 0.0109 0.0109
Trypanosoma brucei histone deacetylase 1 0.0064 0.0109 0.0198
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0118 0.0217 0.0217
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0118 0.0217 0.0398
Brugia malayi Serotonin/octopamine receptor family protein 7 0.018 0.0342 0.0342
Echinococcus granulosus dro:myosuppressin receptor 0.018 0.0342 0.0342
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.005 0.0081 0.1838
Trypanosoma brucei histone deacetylase 2 0.0018 0.0016 0.0027
Echinococcus granulosus vesicular acetylcholine transporter 0.497 1 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0023 0.0025 0.0025
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0025 0.0025
Echinococcus multilocularis neuropeptide Y receptor 0.018 0.0342 0.0342
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.02 0.1063
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.002 0.002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0003 0.0003
Onchocerca volvulus 0.0023 0.0026 0.0026
Echinococcus granulosus neuropeptide receptor A26 0.018 0.0342 0.0342
Echinococcus granulosus aminopeptidase N 0.0398 0.0782 0.0782
Schistosoma mansoni 6-phosphofructokinase 0.011 0.02 0.02
Entamoeba histolytica aminopeptidase, putative 0.0144 0.0269 0.4592
Trypanosoma cruzi Aminopeptidase M1, putative 0.0144 0.0269 0.0495
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0069 0.0069
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0069 0.0069
Brugia malayi Cation transporter family protein 0.0023 0.0025 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0031 0.0031
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.0398
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.005 0.0081 0.2198
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.005 0.0081 0.0384
Echinococcus granulosus histone deacetylase 6 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0023 0.0025 0.0025
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni rhodopsin-like orphan GPCR 0.018 0.0342 0.0342
Brugia malayi ORL1-like opioid receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) phosphofructokinase 0.011 0.02 0.02
Loa Loa (eye worm) carboxylesterase 0.0139 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Brugia malayi PHD-finger family protein 0.0051 0.0082 0.0082
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.005 0.0081 0.0146
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.1038
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0026 0.0032 0.0032
Onchocerca volvulus 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0031 0.0031
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0118 0.0217 0.0217
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0105 0.0105
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.005 0.0081 0.1838
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.005 0.0081 0.2198
Echinococcus granulosus SAM and MBT domain containing protein 0.0095 0.017 0.017
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.002 0.002
Plasmodium vivax histone deacetylase, putative 0.0018 0.0016 0.0216
Loa Loa (eye worm) hypothetical protein 0.0348 0.068 0.068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.018 0.0342 0.0342
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0084 0.2294
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.005 0.0081 0.0081
Echinococcus multilocularis G-protein coupled receptor, putative 0.018 0.0342 0.0342
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.0031 0.0031
Echinococcus granulosus 7tm_1 domain containing protein 0.018 0.0342 0.0342
Onchocerca volvulus 0.0023 0.0025 0.0025
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.005 0.0081 0.0081
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0025 0.0025
Brugia malayi isocitrate dehydrogenase 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) glutathione reductase 0.0232 0.0447 0.0447
Mycobacterium tuberculosis Probable hydrolase 0.0144 0.0269 0.1438
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0029 0.0037 0.0037
Echinococcus granulosus beta LACTamase domain containing family member 0.0144 0.0269 0.0269
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0016 0.0016
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0118 0.0217 0.0398
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.02 0.02
Schistosoma mansoni bromodomain containing protein 0.0127 0.0235 0.0235
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0006 0.0135
Trypanosoma brucei Aminopeptidase M1, putative 0.0144 0.0269 0.0495
Toxoplasma gondii aminopeptidase N protein 0.0051 0.0081 0.0387
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0012 0.0003 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.018 0.0342 0.0342
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0003 0.0003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0026 0.0026
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0023 0.0025 0.0025
Onchocerca volvulus 0.0095 0.017 0.017
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.019 0.0362 1
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni biogenic amine (5HT) receptor 0.018 0.0342 0.0342
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Brugia malayi nuclear hormone receptor family member odr-7 0.0012 0.0003 0.0003
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Onchocerca volvulus 0.0012 0.0003 0.0003
Schistosoma mansoni nAChR subunit 0.0023 0.0025 0.0025
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0014 0.0007 0.0007
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0118 0.0217 0.0217
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0308 0.0308
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0084 0.0084
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0023 0.0025 0.0025
Entamoeba histolytica phosphofructokinase, putative 0.011 0.02 0.3406
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0051 0.0081 0.0147
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0023 0.0025 0.0025
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.005 0.0081 0.0406
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0007 0.0007
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0118 0.0217 0.0217
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.005 0.0081 0.0146
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.005 0.0081 0.1357
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.014 0.0262 0.0262
Onchocerca volvulus 0.0023 0.0025 0.0025
Echinococcus granulosus tm gpcr rhodopsin 0.018 0.0342 0.0342
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Entamoeba histolytica phosphofructokinase, putative 0.011 0.02 0.3406
Echinococcus multilocularis g protein coupled receptor 0.018 0.0342 0.0342
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0118 0.0217 0.5978
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0007 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0118 0.0217 0.0398
Echinococcus granulosus tm gpcr rhodopsin 0.018 0.0342 0.0342
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0084 0.0084
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.005 0.0081 0.0406
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0031 0.0031
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0003 0.0003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.0123 0.0123
Loa Loa (eye worm) PDE1B protein 0.0118 0.0217 0.0217
Toxoplasma gondii selenide, water dikinase 0.005 0.0081 0.0384
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0039 0.0167
Brugia malayi neuropeptide F receptor 0.018 0.0342 0.0342
Onchocerca volvulus 0.018 0.0342 0.0342
Echinococcus multilocularis rhodopsin orphan GPCR 0.018 0.0342 0.0342
Schistosoma mansoni glutamate synthase 0.005 0.0081 0.0081
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.005 0.0081 0.0081
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0118 0.0217 0.0217
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.018 0.0342 0.0342
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0026 0.0032 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0498 0.0984 0.1813
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0139 0.0258 0.0258
Echinococcus multilocularis rhodopsin orphan GPCR 0.018 0.0342 0.0342
Onchocerca volvulus 0.018 0.0342 0.0342
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0118 0.0217 0.0217
Schistosoma mansoni zinc finger protein 0.004 0.0061 0.0061
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.005 0.0081 0.0146
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus multilocularis rhodopsin orphan GPCR 0.018 0.0342 0.0342
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.1038
Loa Loa (eye worm) programmed cell death 8 0.005 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0677 0.1345 0.2479
Loa Loa (eye worm) doublecortin family protein 0.002 0.002 0.002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0012 0.0003 0.0003
Schistosoma mansoni sodium-dependent amino acid transporter 0.0026 0.0032 0.0032
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0032 0.0032
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0086 0.0152 0.2571
Echinococcus multilocularis alpha 1A adrenergic receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) MBCTL1 0.0108 0.0196 0.0196
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0012 0.0003 0.0003
Schistosoma mansoni polycystin 1-related 0.002 0.002 0.002
Echinococcus granulosus biogenic amine 5HT receptor 0.018 0.0342 0.0342
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0108 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0254 0.0491 0.0491
Echinococcus granulosus histone acetyltransferase MYST2 0.0108 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Mycobacterium tuberculosis Probable dehydrogenase 0.005 0.0081 0.0406
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0081 0.2198
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Trypanosoma brucei histone deacetylase 4 0.0018 0.0016 0.0027
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0003 0.0003
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0301 0.0585 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Echinococcus multilocularis cpg binding protein 0.0034 0.0048 0.0048
Plasmodium falciparum amino acid transporter, putative 0.0026 0.0032 0.057
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0017 0.0244
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0025 0.0025
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0118 0.0217 0.0398
Schistosoma mansoni histone deacetylase hda2 0.0018 0.0016 0.0016
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0016 0.0027
Echinococcus granulosus thioredoxin glutathione reductase 0.0232 0.0447 0.0447
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Echinococcus granulosus nAChR subunit 0.0023 0.0025 0.0025
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0118 0.0217 0.0217
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.019 0.0362 0.0362
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0031 0.0031
Onchocerca volvulus 0.018 0.0342 0.0342
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.1038
Echinococcus granulosus biogenic amine 5HT receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0154 0.0289 0.0289
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0084 0.0153
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.012 0.0221 0.0221
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0139 0.026 0.026
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0012 0.0012
Mycobacterium tuberculosis Conserved protein 0.0144 0.0269 0.1438
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0144 0.0269 0.1438
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0051 0.0081 0.1694
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.018 0.0342 0.0342
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0006 0.0083
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.0031 0.0031
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.005 0.0081 0.1838
Schistosoma mansoni hypothetical protein 0.018 0.0342 0.0342
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.018 0.0342 0.0342
Entamoeba histolytica hypothetical protein 0.0012 0.0004 0.0037
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0081 0.2198
Brugia malayi hypothetical protein 0.0014 0.0006 0.0006
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0118 0.0217 0.0217
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0031 0.0031
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0144 0.0269 0.0269
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.019 0.0362 0.1949
Mycobacterium tuberculosis Putative ferredoxin reductase 0.005 0.0081 0.0406
Trichomonas vaginalis penicillin-binding protein, putative 0.0144 0.0269 0.7414
Echinococcus granulosus smad 0.0016 0.0012 0.0012
Brugia malayi hypothetical protein 0.0023 0.0026 0.0026
Brugia malayi intermediate filament protein 0.0028 0.0035 0.0035
Toxoplasma gondii thioredoxin reductase 0.0232 0.0447 0.2285
Brugia malayi G-protein coupled receptor 0.018 0.0342 0.0342
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0052 0.0236
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Onchocerca volvulus 0.018 0.0342 0.0342
Echinococcus granulosus peptide allatostatin:somatostatin 0.018 0.0342 0.0342
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0025 0.0025
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0017 0.0017
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0025 0.0025
Echinococcus multilocularis musashi 0.0028 0.0035 0.0035
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0118 0.0217 0.0217
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0069 0.0069
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0093 0.0167 0.0167
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0039 0.0624
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Echinococcus multilocularis neuropeptide Y receptor 0.018 0.0342 0.0342
Plasmodium falciparum glutathione reductase 0.0232 0.0447 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0039 0.0641
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0032 0.0032
Mycobacterium ulcerans aminopeptidase N PepN 0.0144 0.0269 0.732
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.018 0.0342 0.0342
Schistosoma mansoni nuclear receptor 0.0012 0.0003 0.0003
Mycobacterium ulcerans carboxylesterase, LipT 0.0023 0.0026 0.0259
Brugia malayi orphan nuclear receptor NR2E1 0.0012 0.0003 0.0003
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0118 0.0217 0.5978
Brugia malayi RE15519p 0.018 0.0342 0.0342
Schistosoma mansoni amine GPCR 0.018 0.0342 0.0342
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus granulosus histone deacetylase 6 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0144 0.0269 0.7294
Schistosoma mansoni neuropeptide receptor 0.018 0.0342 0.0342
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0031 0.0031
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0051 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0012 0.0003 0.0003
Brugia malayi G-protein coupled receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0101 0.0491
Loa Loa (eye worm) hypothetical protein 0.0064 0.0109 0.0109
Brugia malayi MH1 domain containing protein 0.0016 0.0012 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.02 0.5519
Plasmodium vivax ferrodoxin reductase, putative 0.005 0.0081 0.1682
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.002 0.002
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) melatonin receptor type 1A 0.018 0.0342 0.0342
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.005 0.0081 0.0146
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Brugia malayi Doublecortin family protein 0.002 0.002 0.002
Brugia malayi Peptidase family M1 containing protein 0.0398 0.0782 0.0782
Schistosoma mansoni ap endonuclease 0.0019 0.0017 0.0017
Mycobacterium ulcerans aminopeptidase N PepN 0.0051 0.0081 0.1853
Echinococcus multilocularis neuropeptide receptor 0.018 0.0342 0.0342
Mycobacterium ulcerans flavoprotein disulfide reductase 0.019 0.0362 1
Onchocerca volvulus 0.0023 0.0026 0.0026
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0108 0.0196 0.0196
Brugia malayi TATA binding protein associated factor 0.0051 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus histone deacetylase 3 0.0064 0.0109 0.0109
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0677 0.1345 0.2479
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0052 0.1408
Leishmania major histone deacetylase, putative 0.0064 0.0109 0.0198
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0064 0.0109 0.2984
Onchocerca volvulus 0.0028 0.0035 0.0035
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0032 0.0032
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0016 0.021
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0084 0.2294
Echinococcus multilocularis Smad4 0.0016 0.0012 0.0012
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0032 0.013
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0016 0.0016
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.057 0.1129 0.208
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0031 0.0031
Brugia malayi neuropeptide F receptor 0.018 0.0342 0.0342
Brugia malayi Isocitrate dehydrogenase 0.0014 0.0007 0.0007
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0031 0.0031
Schistosoma mansoni neurotransmitter gated ion channel 0.0012 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.018 0.0342 0.0342
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.018 0.0342 0.0342
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0003 0.0003
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0032 0.0032
Onchocerca volvulus Huntingtin homolog 0.0119 0.0219 0.0219
Onchocerca volvulus 0.0144 0.0269 0.0269
Echinococcus granulosus 7TM GPCR rhodopsin 0.018 0.0342 0.0342
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.0139 0.0258 0.0258
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0006 0.0135
Echinococcus multilocularis thioredoxin glutathione reductase 0.0232 0.0447 0.0447
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0031 0.0031
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0084 0.0084
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.018 0.0342 0.0342
Echinococcus granulosus histone deacetylase 6 0.0018 0.0016 0.0016
Onchocerca volvulus 0.002 0.002 0.002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0032 0.0032
Echinococcus granulosus acetylcholinesterase 0.0139 0.0258 0.0258
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0031 0.0031
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.4777
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0969 0.1933 0.1933
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0219 0.0219
Echinococcus multilocularis histone deacetylase 6 0.0018 0.0016 0.0016
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.005 0.0081 0.0081
Onchocerca volvulus 0.018 0.0342 0.0342
Schistosoma mansoni amine GPCR 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0023 0.0025 0.0025
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.005 0.0081 0.1838
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0969 0.1933 0.1933
Echinococcus multilocularis acetylcholinesterase 0.0139 0.0258 0.0258
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.0308 0.0308
Onchocerca volvulus Neuropeptide F receptor homolog 0.018 0.0342 0.0342
Schistosoma mansoni lamin 0.0028 0.0035 0.0035
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0031
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0144 0.0269 0.1438
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.018 0.0342 0.0342
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0039 0.0216
Toxoplasma gondii histone deacetylase HDAC1 0.0018 0.0016 0.0049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0069 0.0069
Trichomonas vaginalis mercuric reductase, putative 0.019 0.0362 1
Loa Loa (eye worm) G-protein coupled receptor 0.018 0.0342 0.0342
Echinococcus granulosus carboxylesterase 5A 0.0139 0.0258 0.0258
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.019 0.0362 1
Entamoeba histolytica glutamate synthase beta subunit, putative 0.005 0.0081 0.1357
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0093 0.0167 0.0306
Onchocerca volvulus 0.0012 0.0004 0.0004
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0023 0.0025 0.0025
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0026 0.0108
Mycobacterium ulcerans beta-lactamase 0.0144 0.0269 0.7294
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0014 0.0007 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0031 0.0031
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0032 0.0032
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0118 0.0217 0.0398
Onchocerca volvulus 0.005 0.008 0.008
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0016 0.0016
Echinococcus multilocularis smad 0.0016 0.0012 0.0012
Mycobacterium ulcerans hypothetical protein 0.005 0.0081 0.1838
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.057 0.1129 0.208
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0031 0.0031
Echinococcus granulosus somatostatin receptor 0.018 0.0342 0.0342
Brugia malayi 6-phosphofructokinase 0.011 0.02 0.02
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0026 0.069
Brugia malayi ecdysteroid receptor 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) Smad1 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0081 0.0142 0.0142
Toxoplasma gondii histone deacetylase HDAC4 0.0018 0.0016 0.0049
Leishmania major hypothetical protein, conserved 0.005 0.0081 0.0146
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2699 0.5421 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0025 0.0025
Loa Loa (eye worm) carboxylesterase 0.0023 0.0026 0.0026
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0026 0.0032 0.0032
Echinococcus granulosus sex peptide receptor 0.018 0.0342 0.0342
Onchocerca volvulus 0.0028 0.0035 0.0035
Onchocerca volvulus 0.0012 0.0004 0.0004
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0025 0.0025
Echinococcus granulosus neuropeptide FF receptor 2 0.018 0.0342 0.0342
Plasmodium vivax thioredoxin reductase, putative 0.0232 0.0447 1
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0023 0.0025 0.0025
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0031 0.0031
Brugia malayi histone deacetylase 11 0.0018 0.0016 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0052 0.1408
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0118 0.0217 0.0217
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.02 0.5519
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0004 0.0004
Schistosoma mansoni alpha-glucosidase 0.0141 0.0263 0.0263
Echinococcus granulosus zinc finger protein 0.004 0.0061 0.0061
Schistosoma mansoni disulfide oxidoreductase 0.005 0.0081 0.0081
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0118 0.0217 0.0217
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Brugia malayi Cation transporter family protein 0.0023 0.0025 0.0025
Trypanosoma brucei trypanothione reductase 0.0232 0.0447 0.0822
Mycobacterium leprae conserved hypothetical protein 0.0144 0.0269 0.6685
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0732
Brugia malayi MH2 domain containing protein 0.0016 0.0012 0.0012
Toxoplasma gondii hypothetical protein 0.0026 0.0032 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.018 0.0342 0.0342
Loa Loa (eye worm) histone deacetylase 0.0018 0.0016 0.0016
Mycobacterium tuberculosis Conserved protein 0.0144 0.0269 0.1438
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.1038
Echinococcus multilocularis lamin dm0 0.0028 0.0035 0.0035
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.018 0.0342 0.0342
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0084 0.2294
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Trichomonas vaginalis esterase, putative 0.0144 0.0269 0.7414
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0093 0.0167 0.0167
Brugia malayi Carboxylesterase family protein 0.0023 0.0026 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0144 0.0269 0.0493
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0031 0.0031
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0003 0.0003
Entamoeba histolytica histone deacetylase, putative 0.0064 0.0109 0.1842
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) TYRA-2 protein 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0144 0.0269 0.0269
Plasmodium falciparum thioredoxin reductase 0.019 0.0362 0.8071
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0039 0.0732
Loa Loa (eye worm) serotonin transporter b 0.0154 0.0289 0.0289
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0023 0.0025 0.0025
Schistosoma mansoni smad1 5 8 and 0.0016 0.0012 0.0012
Trichomonas vaginalis glutamate synthase, putative 0.005 0.0081 0.2198
Toxoplasma gondii ABC1 family protein 0.0144 0.0269 0.136
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0052 0.0869
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.005 0.0081 0.2198
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0052 0.1408
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0118 0.0217 0.0217
Treponema pallidum sodium- and chloride- dependent transporter 0.0154 0.0289 0.7889
Echinococcus granulosus rhodopsin orphan GPCR 0.018 0.0342 0.0342
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0023 0.0025 0.0025
Brugia malayi Carboxylesterase family protein 0.0139 0.0258 0.0258
Trypanosoma brucei histone deacetylase, putative 0.0018 0.0016 0.0027
Plasmodium falciparum phosphodiesterase delta, putative 0.0118 0.0217 0.4777
Giardia lamblia hypothetical protein 0.0118 0.0217 0.1042
Brugia malayi hypothetical protein 0.002 0.002 0.002
Schistosoma mansoni nAChR subunit 0.0023 0.0025 0.0025
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0007 0.0007
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.005 0.0081 0.1682
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0051 0.0081 0.0081
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.002 0.0297
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0032 0.057
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0144 0.0269 0.0269
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0084 0.0084
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.002 0.002
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0119 0.0219 0.0401
Schistosoma mansoni vesicular acetylcholine transporter 0.497 1 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0084 0.0153
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.019 0.0362 0.8071
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0118 0.0217 0.0398
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0031 0.0031
Echinococcus multilocularis RUN 0.002 0.002 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.018 0.0342 0.0342
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0081 0.2198
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0144 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni gliotactin 0.0023 0.0026 0.0026
Mycobacterium tuberculosis Probable lipase LipD 0.0144 0.0269 0.1438
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0031 0.0031
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0086 0.0152 0.2571
Echinococcus multilocularis tachykinin peptides receptor 99D 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0081 0.2198
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0032 0.0032
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0006 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0031 0.0031
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.018 0.0342 0.0342
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0047 0.0047
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0084 0.0084
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0154 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0144 0.0269 0.0269
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0051 0.0081 0.0081
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0037 0.0037
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Chlamydia trachomatis thioredoxin reductase 0.005 0.0081 0.1483
Echinococcus multilocularis geminin 0.0173 0.0328 0.0328
Onchocerca volvulus 0.018 0.0342 0.0342
Loa Loa (eye worm) thioredoxin reductase 0.0232 0.0447 0.0447
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Leishmania major NADH dehydrogenase, putative 0.005 0.0081 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0031
Mycobacterium ulcerans dehydrogenase 0.005 0.0081 0.1838
Schistosoma mansoni nAChR subunit 0.0023 0.0025 0.0025
Echinococcus multilocularis polycomb protein SCMH1 0.0095 0.017 0.017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.018 0.0342 0.0342
Brugia malayi AKH receptor 0.018 0.0342 0.0342
Mycobacterium ulcerans esterase/lipase LipP 0.0144 0.0269 0.7294
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0023 0.0025 0.0025
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0851 0.1695 0.1695
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus granulosus rhodopsin orphan GPCR 0.018 0.0342 0.0342
Plasmodium falciparum histone deacetylase, putative 0.0018 0.0016 0.0216
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0031 0.0031
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0023 0.0025 0.0025
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.019 0.0362 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0012 0.0003 0.0003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0017 0.0029
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.0123 0.0123
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0025 0.0025
Trypanosoma cruzi histone deacetylase 1, putative 0.0064 0.0109 0.0198
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0031
Schistosoma mansoni ap endonuclease 0.0019 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0041 0.0062 0.0062
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.018 0.0342 0.0342
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0139 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Onchocerca volvulus 0.018 0.0342 0.0342
Echinococcus multilocularis neuropeptide FF receptor 2 0.018 0.0342 0.0342
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0025 0.0025
Echinococcus multilocularis peregrin 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0031
Echinococcus granulosus fetal alzheimer antigen falz 0.0046 0.0072 0.0072
Loa Loa (eye worm) neuropeptide F receptor 0.018 0.0342 0.0342
Onchocerca volvulus 0.0012 0.0003 0.0003
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0118 0.0217 0.0398
Trypanosoma brucei C-8 sterol isomerase, putative 0.2699 0.5421 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0023 0.0026 0.0108
Loa Loa (eye worm) histone deacetylase 11 0.0018 0.0016 0.0016
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.4777
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0006 0.0006
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0144 0.0269 0.0495
Brugia malayi beta-lactamase 0.0144 0.0269 0.0269
Leishmania major hypothetical protein, conserved 0.0118 0.0217 0.0398
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Onchocerca volvulus 0.0023 0.0025 0.0025
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0081 0.2198
Leishmania major cAMP-specific phosphodiesterase, putative 0.0118 0.0217 0.0398
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0006 0.0135
Onchocerca volvulus 0.018 0.0342 0.0342
Onchocerca volvulus 0.018 0.0342 0.0342
Leishmania major ATP-dependent phosphofructokinase 0.011 0.02 0.0367
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.005 0.0081 0.0081
Brugia malayi excitatory GABA receptor EXP-1A 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) G-protein coupled receptor 0.018 0.0342 0.0342
Echinococcus granulosus rhodopsin orphan GPCR 0.018 0.0342 0.0342
Schistosoma mansoni Smad4 0.0016 0.0012 0.0012
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0144 0.0269 0.0269
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Brugia malayi nuclear hormone receptor family member nhr-6 0.0012 0.0003 0.0003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.019 0.0362 0.0665
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0006 0.0135
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0154 0.0289 0.0289
Brugia malayi glutamate synthase 0.005 0.0081 0.0081
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0017 0.0442
Entamoeba histolytica glutamate synthase beta subunit, putative 0.005 0.0081 0.1357
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0051 0.0081 0.1694
Brugia malayi histone deacetylase 3 (HD3) 0.0064 0.0109 0.0109
Echinococcus multilocularis aminopeptidase N 0.0398 0.0782 0.0782
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0051 0.0081 0.0147
Echinococcus multilocularis neuropeptides capa receptor 0.018 0.0342 0.0342
Plasmodium falciparum LCCL domain-containing protein 0.002 0.002 0.0297
Echinococcus granulosus neuropeptide Y receptor 0.018 0.0342 0.0342
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0081 0.0146
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0144 0.0269 0.0269
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.497 1 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.005 0.0081 0.0406
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Trypanosoma cruzi trypanothione reductase, putative 0.0232 0.0447 0.0822
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0051 0.0081 0.0081
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0797 0.1585 0.1585
Brugia malayi nuclear hormone receptor 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0144 0.0269 0.0269
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.005 0.0081 0.0146
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0051 0.0081 0.1694
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.018 0.0342 0.0342
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0084 0.0348
Schistosoma mansoni histone deacetylase 4 5 0.0018 0.0016 0.0016
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.005 0.0081 0.2198
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0144 0.0269 0.0269
Onchocerca volvulus 0.002 0.002 0.002
Echinococcus granulosus hypothetical protein 0.018 0.0342 0.0342
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.019 0.0362 0.8071
Brugia malayi Dopamine receptor protein 2 0.018 0.0342 0.0342
Loa Loa (eye worm) histone deacetylase 7A 0.0018 0.0016 0.0016
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0118 0.0217 0.0398
Schistosoma mansoni hypothetical protein 0.005 0.0081 0.0081
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0377 0.0738 0.0738
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0109 0.2984
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0004 0.0004
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0016 0.0027
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Echinococcus multilocularis histone deacetylase 1 0.0064 0.0109 0.0109
Echinococcus multilocularis zinc finger protein 0.004 0.0061 0.0061
Onchocerca volvulus 0.0023 0.0025 0.0025
Echinococcus granulosus histone deacetylase 7 0.0018 0.0016 0.0016
Schistosoma mansoni neuropeptide f receptor 76f 0.018 0.0342 0.0342
Loa Loa (eye worm) isocitrate dehydrogenase 0.0014 0.0007 0.0007
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Loa Loa (eye worm) GABA receptor subunit 0.0012 0.0004 0.0004
Brugia malayi Bromodomain containing protein 0.015 0.0282 0.0282
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.018 0.0342 0.0342
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0047 0.0047
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.018 0.0342 0.0342
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0006
Leishmania major histone deacetylase, putative 0.0018 0.0016 0.0027
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Echinococcus multilocularis allatostatin A receptor 0.018 0.0342 0.0342
Giardia lamblia NADH oxidase lateral transfer candidate 0.019 0.0362 0.1798
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0144 0.0269 0.0269
Onchocerca volvulus 0.0026 0.0031 0.0031
Brugia malayi Thioredoxin reductase 0.0232 0.0447 0.0447
Echinococcus multilocularis glutamate synthase 0.005 0.0081 0.0081
Echinococcus multilocularis glycine receptor subunit beta 0.0023 0.0025 0.0025
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.497 1 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Schistosoma mansoni histamine h1 receptor 0.018 0.0342 0.0342
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0026 0.0032 0.0032
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0007 0.001
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.005 0.0081 0.0406
Schistosoma mansoni sulfide quinone reductase 0.005 0.0081 0.0081
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0006 0.0006
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus granulosus nAChR subunit 0.0012 0.0004 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0052 0.1408
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0118 0.0217 0.4777
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0039 0.0112
Echinococcus granulosus neuropeptide receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.018 0.0342 0.0342
Echinococcus multilocularis g protein coupled receptor 0.018 0.0342 0.0342
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0308 0.0308
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0032 0.0032
Brugia malayi Peptidase family M1 containing protein 0.0144 0.0269 0.0269
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0017 0.0273
Brugia malayi Dopamine receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.002
Echinococcus granulosus g protein coupled receptor 0.018 0.0342 0.0342
Echinococcus granulosus cpg binding protein 0.0034 0.0048 0.0048
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0023 0.0025 0.0025
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0039 0.0167
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0118 0.0217 0.0398
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.005 0.0081 0.0406
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0069 0.0069
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.018 0.0342 0.0342
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0032 0.0032
Schistosoma mansoni sulfide quinone reductase 0.005 0.0081 0.0081
Echinococcus granulosus neuropeptide s receptor 0.018 0.0342 0.0342
Echinococcus granulosus polycomb protein SCMH1 0.0095 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.0093 0.0167 0.0167
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0023 0.0025 0.0025
Loa Loa (eye worm) transcription factor SMAD2 0.0237 0.0456 0.0456
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0084 0.0402
Echinococcus multilocularis rhodopsin orphan GPCR 0.018 0.0342 0.0342
Schistosoma mansoni histone deacetylase 1 2 3 0.0018 0.0016 0.0016
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.019 0.0362 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.005 0.0081 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0026 0.0026
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0025 0.0025
Mycobacterium tuberculosis Probable lipase LipE 0.0144 0.0269 0.1438
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0026 0.0108
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0012 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.018 0.0342 0.0342
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.005 0.0081 0.0384
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0144 0.0269 0.0269
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0006 0.0009
Schistosoma mansoni cpg binding protein 0.0034 0.0048 0.0048
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.005 0.0081 0.0384
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Brugia malayi Carboxylesterase family protein 0.0023 0.0026 0.0026
Schistosoma mansoni alpha glucosidase 0.0036 0.0052 0.0052
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.0031 0.0031
Schistosoma mansoni nuclear receptor nhr-48 0.0012 0.0003 0.0003
Toxoplasma gondii exonuclease III APE 0.0019 0.0017 0.0056
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.005 0.0081 0.1838
Echinococcus multilocularis serotonin transporter 0.0154 0.0289 0.0289
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0084 0.0084
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0144 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Echinococcus multilocularis neuropeptide s receptor 0.018 0.0342 0.0342
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0052 0.0052
Echinococcus multilocularis histone deacetylase 3 0.0064 0.0109 0.0109
Echinococcus multilocularis histone deacetylase 0.0018 0.0016 0.0016
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.018 0.0342 0.0342
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Mycobacterium tuberculosis Probable oxidoreductase 0.019 0.0362 0.1949
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0109 0.2984
Brugia malayi MAP kinase sur-1 0.0052 0.0084 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.005 0.005
Trichomonas vaginalis glutamate synthase, putative 0.005 0.0081 0.2198
Brugia malayi hypothetical protein 0.0014 0.0006 0.0006
Echinococcus multilocularis tumor protein p63 0.0341 0.0667 0.0667
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Giardia lamblia Thioredoxin reductase 0.005 0.0081 0.0331
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0012 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.002 0.002 0.002
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0025 0.0025
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.005 0.0081 0.0331
Schistosoma mansoni amine GPCR 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Echinococcus granulosus nuclear receptor nhr 48 0.0012 0.0003 0.0003
Brugia malayi larval opioid receptor 0.018 0.0342 0.0342
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0118 0.0217 0.0217
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0031 0.0031
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.018 0.0342 0.0342
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0118 0.0217 0.0217
Schistosoma mansoni histone deacetylase 0.0064 0.0109 0.0109
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0026 0.0032 0.0032
Trypanosoma cruzi aminopeptidase, putative 0.0051 0.0081 0.0147
Schistosoma mansoni hypothetical protein 0.018 0.0342 0.0342
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0918 0.1829 1
Trypanosoma brucei aminopeptidase, putative 0.0051 0.0081 0.0147
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0023 0.0025 0.0025
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.019 0.0362 0.0665
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.019 0.0362 1
Trypanosoma brucei protein kinase, putative 0.0052 0.0084 0.0153
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0046 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0217 0.5978
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.0308 0.0308
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.4777
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.02 0.02
Brugia malayi MH2 domain containing protein 0.0016 0.0012 0.0012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Brugia malayi 6-phosphofructokinase 0.011 0.02 0.02
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0029 0.0037 0.0037
Echinococcus granulosus fmrfamide receptor 0.018 0.0342 0.0342
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0052 0.0052
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0012 0.0003 0.0003
Leishmania major trypanothione reductase 0.0232 0.0447 0.0822
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.019 0.0362 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0014 0.0007 0.0007
Schistosoma mansoni growth hormone secretagogue receptor 0.018 0.0342 0.0342
Schistosoma mansoni lipoxygenase 0.0084 0.0149 0.0149
Echinococcus granulosus leukotriene A 4 hydrolase 0.0051 0.0081 0.0081
Entamoeba histolytica thioredoxin reductase, putative 0.005 0.0081 0.1357
Echinococcus multilocularis nuclear receptor nhr 48 0.0012 0.0003 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0017 0.0244
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0118 0.0217 0.0217
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0023 0.0025 0.0025
Mycobacterium tuberculosis Probable reductase 0.005 0.0081 0.0406
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0026 0.0026
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0051 0.0081 0.0147
Loa Loa (eye worm) hypothetical protein 0.0144 0.0269 0.0269
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.019 0.0362 0.0362
Onchocerca volvulus 0.0095 0.017 0.017
Echinococcus multilocularis histone deacetylase 8 0.0018 0.0016 0.0016
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0021 0.0541
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0144 0.0269 0.0269
Brugia malayi hypothetical protein 0.002 0.002 0.002
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0025 0.0025
Mycobacterium ulcerans hypothetical protein 0.0144 0.0269 0.7294
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0076 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Brugia malayi Histone deacetylase family protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) RecQ helicase 0.0021 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0139 0.0258 0.0258
Trypanosoma cruzi hypothetical protein, conserved 0.0118 0.0217 0.0398
Echinococcus multilocularis G protein coupled receptor 139 0.018 0.0342 0.0342
Echinococcus granulosus lamin 0.0028 0.0035 0.0035
Echinococcus multilocularis isocitrate dehydrogenase 0.0014 0.0007 0.0007
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Trypanosoma cruzi NADH dehydrogenase, putative 0.005 0.0081 0.0146
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0017 0.0029
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0144 0.0269 0.0495
Giardia lamblia Hypothetical protein 0.0118 0.0217 0.1042
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0026 0.0026
Onchocerca volvulus 0.0144 0.0269 0.0269
Trypanosoma cruzi histone deacetylase, putative 0.0018 0.0016 0.0027
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.005 0.0081 0.0081
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Schistosoma mansoni myosin xvIII 0.018 0.0342 0.0342
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.005 0.0081 0.0406
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0007 0.001
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Trypanosoma cruzi hypothetical protein, conserved 0.0118 0.0217 0.0398
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.018 0.0342 0.0342
Onchocerca volvulus 0.0154 0.0289 0.0289
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.018 0.0342 0.0342
Brugia malayi Peptidase family M1 containing protein 0.0051 0.0081 0.0081
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.005 0.005
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0118 0.0217 0.0398
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Onchocerca volvulus 0.018 0.0342 0.0342
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.005 0.0081 0.0081
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0032 0.013
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0154 0.0289 0.0289
Leishmania major hypothetical protein, conserved 0.003 0.004 0.0072
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Echinococcus granulosus histone deacetylase 1 0.0064 0.0109 0.0109
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.005 0.0081 0.0081
Echinococcus multilocularis orexin receptor type 2 0.018 0.0342 0.0342
Schistosoma mansoni hypothetical protein 0.0173 0.0328 0.0328
Brugia malayi Carboxylesterase family protein 0.0023 0.0026 0.0026
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0144 0.0269 0.0495
Schistosoma mansoni amine GPCR 0.018 0.0342 0.0342
Loa Loa (eye worm) nuclear receptor NHR-67 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Plasmodium vivax hypothetical protein, conserved 0.0144 0.0269 0.5953
Toxoplasma gondii histone deacetylase HDAC5 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.018 0.0342 0.0342
Schistosoma mansoni neuropeptide F-like receptor 0.018 0.0342 0.0342
Schistosoma mansoni nAChR subunit 0.0023 0.0025 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0031 0.0031
Schistosoma mansoni nAChR subunit 0.0023 0.0025 0.0025
Brugia malayi putative neuropeptide receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni hypothetical protein 0.003 0.004 0.004
Brugia malayi conserved hypotetical protein 0.0012 0.0003 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.0269 0.7414
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0051 0.0081 0.1694
Onchocerca volvulus 0.018 0.0342 0.0342
Giardia lamblia Histone deacetylase 0.0064 0.0109 0.0478
Brugia malayi hypothetical protein 0.0051 0.0081 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0118 0.0217 0.0398
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0052 0.0052
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0006 0.0006
Onchocerca volvulus 0.0051 0.0081 0.0081
Schistosoma mansoni glutamate synthase 0.005 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.018 0.0342 0.0342
Brugia malayi beta-lactamase family protein 0.0144 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0031
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0144 0.0269 0.0269
Onchocerca volvulus 0.0144 0.0269 0.0269
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.005 0.0081 0.1682
Leishmania major hypothetical protein, conserved 0.0118 0.0217 0.0398
Mycobacterium ulcerans ferredoxin reductase 0.005 0.0081 0.1838
Echinococcus granulosus orexin receptor type 2 0.018 0.0342 0.0342
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0031 0.0031
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.057 0.1129 0.208
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0034
Schistosoma mansoni smad1 5 8 and 0.0016 0.0012 0.0012
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.005 0.0081 0.0384
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0032 0.0032
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0118 0.0217 0.0217
Schistosoma mansoni cpg binding protein 0.0034 0.0048 0.0048
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0084 0.0153
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0021 0.0541
Toxoplasma gondii histone deacetylase HDAC2 0.0064 0.0109 0.0531
Loa Loa (eye worm) hypothetical protein 0.005 0.0081 0.0081
Leishmania major histone deacetylase, putative 0.0018 0.0016 0.0027
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.019 0.0362 0.1949
Trypanosoma cruzi ISWI complex protein 0.003 0.004 0.0072
Echinococcus multilocularis serotonin receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0095 0.017 0.017
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0969 0.1933 0.1933
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.0269 0.7414
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0118 0.0217 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.018 0.0342 0.0342
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0032 0.0032
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0118 0.0217 0.0217
Schistosoma mansoni glutamate synthase 0.005 0.0081 0.0081
Mycobacterium leprae Probable lipase LipE 0.0144 0.0269 0.6685
Loa Loa (eye worm) neuropeptide F receptor 0.018 0.0342 0.0342
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0012 0.0012
Plasmodium falciparum glutathione reductase 0.019 0.0362 0.8071
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0154 0.0289 0.0289
Schistosoma mansoni lipoxygenase 0.0121 0.0222 0.0222
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.005 0.0081 0.0406
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0026 0.0026
Plasmodium vivax histone deacetylase 1, putative 0.0064 0.0109 0.2326
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0032 0.0032
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.019 0.0362 0.0362
Leishmania major C-8 sterol isomerase-like protein 0.2699 0.5421 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0119 0.0219 0.0219
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.0812 0.0812
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0017 0.0029
Brugia malayi Serotonin receptor 0.018 0.0342 0.0342
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0025 0.0025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.018 0.0342 0.0342
Plasmodium falciparum thioredoxin reductase 0.0232 0.0447 1
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0051 0.0081 0.0147
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.005 0.0081 0.1838
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0031 0.0031
Echinococcus granulosus neuropeptide Y receptor 0.018 0.0342 0.0342
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.0398
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0851 0.1695 0.1695
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus multilocularis serotonin receptor 0.018 0.0342 0.0342
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Onchocerca volvulus 0.005 0.0081 0.0081
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) histone deacetylase 1 0.0064 0.0109 0.0109
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0003 0.0003
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0118 0.0217 0.0217
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0118 0.0217 0.0217
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0118 0.0217 0.0217
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.005 0.0081 0.0146
Echinococcus granulosus alpha 1A adrenergic receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) TATA binding protein associated factor 0.0051 0.0081 0.0081
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0031
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.02 0.4256
Echinococcus multilocularis neuroligin 0.0023 0.0026 0.0026
Loa Loa (eye worm) follicle stimulating hormone receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni loxhd1 0.002 0.002 0.002
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0118 0.0217 0.0217
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0144 0.0269 0.7439
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0039 0.0216
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0219 0.5841
Leishmania major hypothetical protein, conserved 0.005 0.0081 0.0146
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0052 0.0094
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Onchocerca volvulus 0.018 0.0342 0.0342
Brugia malayi G protein-coupled receptor F59B2.13 0.018 0.0342 0.0342
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Onchocerca volvulus 0.018 0.0342 0.0342
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.005 0.0081 0.0081
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0023 0.0025 0.0025
Treponema pallidum oxidoreductase 0.005 0.0081 0.1838
Schistosoma mansoni neuropeptide receptor 0.018 0.0342 0.0342
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0025 0.0025
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0023 0.0025 0.0025
Brugia malayi Smad1 0.0016 0.0012 0.0012
Echinococcus multilocularis vesicular acetylcholine transporter 0.497 1 1
Onchocerca volvulus 0.0144 0.0269 0.0269
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0108 0.0196 0.0196
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0009 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.02 0.5519
Schistosoma mansoni amine GPCR 0.018 0.0342 0.0342
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.005 0.0081 0.0146
Echinococcus granulosus 6 phosphofructokinase 0.011 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Plasmodium vivax histone deacetylase 2, putative 0.0018 0.0016 0.0216
Echinococcus granulosus g protein coupled receptor 0.018 0.0342 0.0342
Schistosoma mansoni opsin-like receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0051 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0086 0.0153 0.0153
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0144 0.0269 0.7439
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0039 0.1038
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.4777
Trypanosoma cruzi hypothetical protein, conserved 0.0144 0.0269 0.0493
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0032 0.0032
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.018 0.0342 0.0342
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0069 0.0069
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.005 0.0081 0.0081
Brugia malayi Dopamine receptor protein 1 0.018 0.0342 0.0342
Loa Loa (eye worm) solute carrier family 6 member 4 0.0154 0.0289 0.0289
Brugia malayi nuclear receptor RXR 0.0014 0.0006 0.0006
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.0269 0.7414
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0118 0.0217 0.0398
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0031 0.0031
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0006 0.0009
Plasmodium vivax glutathione reductase, putative 0.0232 0.0447 1
Trichomonas vaginalis histone deacetylase, putative 0.0064 0.0109 0.2984
Schistosoma mansoni cpg binding protein 0.0029 0.0037 0.0037
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0118 0.0217 0.0398
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.018 0.0342 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0217 0.5978
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.019 0.0362 0.8071
Schistosoma mansoni lamin 0.0028 0.0035 0.0035
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0052 0.1408
Onchocerca volvulus Histone deacetylase 10 homolog 0.0018 0.0016 0.0016
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0012 0.0003 0.0003
Leishmania major histone deacetylase, putative 0.0064 0.0109 0.0198
Schistosoma mansoni SET domain protein 0.0015 0.001 0.001
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0032 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0031 0.0031
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0232 0.0447 0.2415
Mycobacterium tuberculosis Conserved protein 0.0144 0.0269 0.1438
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0677 0.1345 0.2479
Treponema pallidum NADH oxidase 0.019 0.0362 1
Echinococcus granulosus Smad4 0.0016 0.0012 0.0012
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0052 0.0052
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0084 0.2294
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0026 0.0026
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus granulosus neuroligin 0.0023 0.0026 0.0026
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.019 0.0362 0.0665
Schistosoma mansoni 6-phosphofructokinase 0.011 0.02 0.02
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Schistosoma mansoni hypothetical protein 0.0173 0.0328 0.0328
Echinococcus multilocularis histone deacetylase 7 0.0018 0.0016 0.0016
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0012 0.0003 0.0003
Schistosoma mansoni rab6-interacting 0.002 0.002 0.002
Onchocerca volvulus Huntingtin homolog 0.0119 0.0219 0.0219
Echinococcus granulosus RUN 0.002 0.002 0.002
Echinococcus granulosus lamin dm0 0.0028 0.0035 0.0035
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.005 0.0081 0.1682
Toxoplasma gondii histone deacetylase HDAC3 0.0064 0.0109 0.0531
Toxoplasma gondii aminopeptidase n, putative 0.0051 0.0081 0.0387
Brugia malayi hypothetical protein 0.0012 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0118 0.0217 0.0398
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0069 0.0069
Brugia malayi hypothetical protein 0.0026 0.0032 0.0032
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0026 0.0026
Loa Loa (eye worm) bromodomain containing protein 0.0035 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0035 0.0035
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0118 0.0217 0.0217
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.1038
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0051 0.0081 0.0147
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0014 0.0006 0.0006
Schistosoma mansoni alpha-glucosidase 0.0141 0.0263 0.0263
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0021 0.0021
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0004
Onchocerca volvulus 0.0398 0.0782 0.0782
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Echinococcus granulosus intermediate filament protein 0.0028 0.0035 0.0035
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0081 0.0146
Trypanosoma cruzi aminopeptidase, putative 0.0144 0.0269 0.0495
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0034 0.0047 0.0047
Plasmodium falciparum histone deacetylase 2 0.0018 0.0016 0.0216
Schistosoma mansoni zinc finger protein 0.003 0.004 0.004
Loa Loa (eye worm) norepinephrine transporter 0.0154 0.0289 0.0289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0031 0.0031
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0144 0.0269 0.0495
Toxoplasma gondii aminopeptidase N, putative 0.0051 0.0081 0.0387
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Schistosoma mansoni biogenic amine receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0006 0.0135
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0031 0.0031
Brugia malayi Carboxylesterase family protein 0.0023 0.0026 0.0026
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.019 0.0362 0.1844
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0031 0.0031
Onchocerca volvulus 0.0026 0.0032 0.0032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0069 0.0069
Brugia malayi phosphofructokinase 0.011 0.02 0.02
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0031 0.0031
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0219 0.0219
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.044 0.0867 0.0867
Leishmania major hypothetical protein, conserved 0.0144 0.0269 0.0493
Loa Loa (eye worm) histone deacetylase 3 0.0064 0.0109 0.0109
Brugia malayi gonadotropin-releasing hormone receptor 2 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0051 0.0081 0.0081
Schistosoma mansoni neuropeptide F-like receptor 0.018 0.0342 0.0342
Schistosoma mansoni acetylcholinesterase 0.0023 0.0026 0.0026
Brugia malayi MH2 domain containing protein 0.0237 0.0456 0.0456
Schistosoma mansoni neuropeptide receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0105 0.019 0.019
Echinococcus granulosus glycine receptor subunit beta 0.0023 0.0025 0.0025
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0012 0.0012
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0118 0.0217 0.0398
Loa Loa (eye worm) acetylcholinesterase 1 0.0139 0.0258 0.0258
Onchocerca volvulus 0.018 0.0342 0.0342
Onchocerca volvulus 0.0026 0.0032 0.0032
Schistosoma mansoni biogenic amine (5HT) receptor 0.018 0.0342 0.0342
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.019 0.0362 0.0362
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0012 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.018 0.0342 0.0342
Brugia malayi histone deacetylase 1 (HD1) 0.0064 0.0109 0.0109
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0969 0.1933 0.1933
Brugia malayi G protein-coupled receptor 0.018 0.0342 0.0342
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0023 0.0025 0.0025
Schistosoma mansoni smad1 5 8 and 0.0016 0.0012 0.0012
Loa Loa (eye worm) mbt repeat family protein 0.0095 0.017 0.017
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0052 0.1408
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0064 0.0109 0.2984
Trypanosoma brucei histone deacetylase 3 0.0018 0.0016 0.0027
Brugia malayi MH1 domain containing protein 0.0016 0.0012 0.0012
Plasmodium vivax amine transporter, putative 0.0026 0.0032 0.057
Brugia malayi nuclear receptor NHR-67 0.0012 0.0003 0.0003
Loa Loa (eye worm) PHD-finger family protein 0.0041 0.0062 0.0062
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0003 0.0003
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0118 0.0217 0.0217
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.0031 0.0031
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0012 0.0012
Onchocerca volvulus 0.0023 0.0025 0.0025
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0006 0.0135
Echinococcus multilocularis g-protein coupled receptor 0.018 0.0342 0.0342
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0377 0.0738 0.0738
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0017 0.0017
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0031 0.0031
Loa Loa (eye worm) MH2 domain-containing protein 0.0237 0.0456 0.0456
Schistosoma mansoni adenoreceptor 0.018 0.0342 0.0342
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0035 0.0035
Brugia malayi Cation transporter family protein 0.0023 0.0025 0.0025
Loa Loa (eye worm) DR-78 0.0012 0.0003 0.0003
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Schistosoma mansoni sex comb on midleg homolog 0.0095 0.017 0.017
Brugia malayi Histone deacetylase 1 0.0064 0.0109 0.0109
Brugia malayi Serotonin receptor 0.018 0.0342 0.0342
Trichomonas vaginalis penicillin-binding protein, putative 0.0144 0.0269 0.7414
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0084 0.0153
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0031 0.0031
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Brugia malayi Melatonin receptor type 1A 0.018 0.0342 0.0342
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0119 0.0219 0.0219
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.019 0.0362 0.1949
Echinococcus granulosus serotonin receptor 0.018 0.0342 0.0342
Trichomonas vaginalis disulfide oxidoreductase, putative 0.005 0.0081 0.2198
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0969 0.1933 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0014 0.0007 0.001
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0052 0.0869
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.02 0.5312
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0064 0.0109 0.2984
Loa Loa (eye worm) beta-lactamase 0.0144 0.0269 0.0269
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0039 0.0167
Echinococcus multilocularis histone acetyltransferase MYST2 0.0108 0.0196 0.0196
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0017 0.0017
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0118 0.0217 0.4777
Schistosoma mansoni biogenic amine receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0031
Echinococcus granulosus bloom syndrome protein 0.0021 0.0021 0.0021
Plasmodium falciparum histone deacetylase 1 0.0064 0.0109 0.2326
Brugia malayi mbt repeat family protein 0.0095 0.017 0.017
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.005 0.005
Onchocerca volvulus 0.0029 0.0037 0.0037
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0039 0.0732
Giardia lamblia DNA repair protein RAD52 0.0301 0.0585 0.2965
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.057 0.1129 0.208
Brugia malayi GnHR receptor homolog 0.018 0.0342 0.0342
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.019 0.0362 0.8071
Echinococcus multilocularis acetylcholinesterase 0.0139 0.0258 0.0258
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0003 0.0003
Loa Loa (eye worm) LGC-31 protein 0.0023 0.0025 0.0025
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0118 0.0217 0.5978
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0095 0.017 0.017
Echinococcus multilocularis biogenic amine (5HT) receptor 0.018 0.0342 0.0342
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Trypanosoma cruzi NADH dehydrogenase, putative 0.005 0.0081 0.0146
Schistosoma mansoni histone deacetylase hda2 0.0018 0.0016 0.0016
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0084 0.0153
Loa Loa (eye worm) hypothetical protein 0.0093 0.0167 0.0167
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0052 0.0094
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0039 0.1038
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0051 0.0081 0.0081
Schistosoma mansoni neuropeptide receptor 0.018 0.0342 0.0342
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0006 0.0006
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0009 0.0009
Brugia malayi putative neuropeptide receptor NPR1 0.018 0.0342 0.0342
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.005 0.0081 0.0081
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0119 0.0219 0.1163
Echinococcus granulosus tachykinin peptides receptor 99D 0.018 0.0342 0.0342
Brugia malayi Bromodomain containing protein 0.0076 0.0132 0.0132
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.018 0.0342 0.0342
Brugia malayi follicle stimulating hormone receptor 0.018 0.0342 0.0342
Trypanosoma brucei hypothetical protein, conserved 0.0118 0.0217 0.0398
Brugia malayi nuclear hormone receptor 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.2699 0.5421 0.5421
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0006 0.0006
Loa Loa (eye worm) ACC-1 protein 0.0023 0.0025 0.0025
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.005 0.0081 0.1357
Loa Loa (eye worm) aminopeptidase N 0.0144 0.0269 0.0269
Loa Loa (eye worm) peptidase family M1 containing protein 0.0305 0.0594 0.0594
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0677 0.1345 0.2479
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0031 0.0031
Schistosoma mansoni cellular tumor antigen P53 0.005 0.008 0.008
Brugia malayi Histone deacetylase family protein 0.0018 0.0016 0.0016
Trypanosoma cruzi trypanothione reductase, putative 0.019 0.0362 0.0665
Entamoeba histolytica disulphide oxidoreductase, putative 0.005 0.0081 0.1357
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0118 0.0217 0.0217
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0032 0.0032
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0144 0.0269 0.0269
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.005 0.0081 0.0384
Trypanosoma cruzi ISWI complex protein 0.003 0.004 0.0072
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0052 0.0094
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0498 0.0984 0.1813
Onchocerca volvulus 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Schistosoma mansoni myelin transcription factor 1 myt1 0.0108 0.0196 0.0196
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0118 0.0217 0.0217
Onchocerca volvulus 0.0023 0.0025 0.0025
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0035 0.0035
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0118 0.0217 0.0217
Loa Loa (eye worm) carboxylesterase 0.0023 0.0026 0.0026
Entamoeba histolytica phosphofructokinase, putative 0.011 0.02 0.3406
Echinococcus multilocularis dro:myosuppressin receptor 0.018 0.0342 0.0342
Brugia malayi hypothetical protein 0.0144 0.0269 0.0269
Echinococcus multilocularis SAM and MBT domain containing protein 0.0095 0.017 0.017
Echinococcus granulosus rhodopsin orphan GPCR 0.018 0.0342 0.0342
Brugia malayi hypothetical protein 0.018 0.0342 0.0342
Echinococcus granulosus glycine receptor subunit beta 0.0023 0.0025 0.0025
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.005 0.0081 0.1838
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.005 0.005
Schistosoma mansoni peptide (allatostatin)-like receptor 0.018 0.0342 0.0342
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0095 0.017 0.017
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0023 0.0025 0.0025
Mycobacterium ulcerans glutamate synthase subunit beta 0.005 0.0081 0.1838
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0023 0.0025 0.0025
Plasmodium vivax histone deacetylase, putative 0.0018 0.0016 0.0216
Loa Loa (eye worm) hypothetical protein 0.0035 0.005 0.005
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0023 0.0025 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.018 0.0342 0.0342
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0084 0.0153
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.018 0.0342 0.0342
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0031 0.0031
Schistosoma mansoni aminopeptidase A (M01 family) 0.0051 0.0081 0.0081
Giardia lamblia Glutamate synthase 0.005 0.0081 0.0331
Treponema pallidum thioredoxin reductase (trxB) 0.005 0.0081 0.1838
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0118 0.0217 0.5978
Schistosoma mansoni sodium/chloride dependent transporter 0.0154 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0005
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.005 0.0081 0.0081
Schistosoma mansoni opsin-like receptor 0.018 0.0342 0.0342
Schistosoma mansoni biogenic amine (dopamine) receptor 0.018 0.0342 0.0342
Echinococcus granulosus g protein coupled receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0118 0.0217 0.0217
Brugia malayi CXXC zinc finger family protein 0.0029 0.0037 0.0037
Onchocerca volvulus 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0033 0.0033
Plasmodium falciparum ferrodoxin reductase-like protein 0.005 0.0081 0.1682
Toxoplasma gondii aldehyde dehydrogenase 0.0119 0.0219 0.11
Echinococcus granulosus serotonin transporter 0.0154 0.0289 0.0289
Mycobacterium tuberculosis Probable esterase LipL 0.0144 0.0269 0.1438
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0118 0.0217 0.5978
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0026 0.0026
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0003 0.0003
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0026 0.0026
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0023 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0031 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0069 0.0069
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0051 0.0081 0.0081
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.005 0.0081 0.0146
Brugia malayi beta-lactamase family protein 0.0144 0.0269 0.0269
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0031 0.0031
Brugia malayi ERG2 and Sigma1 receptor like protein 0.2699 0.5421 0.5421
Schistosoma mansoni hypothetical protein 0.0579 0.1146 0.1146
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.005 0.0081 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0031 0.0031
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0026 0.069
Toxoplasma gondii hypothetical protein 0.0026 0.0032 0.013
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0219 0.5841
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0118 0.0217 0.1092
Onchocerca volvulus 0.018 0.0342 0.0342
Echinococcus granulosus g-protein coupled receptor 0.018 0.0342 0.0342
Loa Loa (eye worm) ACC-1 protein 0.0023 0.0025 0.0025
Brugia malayi tailless protein 0.0012 0.0003 0.0003
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0012 0.0004 0.0004
Plasmodium falciparum phosphodiesterase gamma, putative 0.0118 0.0217 0.4777
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.018 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.138 0.276 0.276
Echinococcus granulosus tumor protein p63 0.0341 0.0667 0.0667
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0007 0.0007
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0498 0.0984 0.1813
Onchocerca volvulus 0.018 0.0342 0.0342
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0046 0.0072 0.0072
Trypanosoma cruzi histone deacetylase 1, putative 0.0064 0.0109 0.0198
Onchocerca volvulus 0.0023 0.0026 0.0026
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0017 0.0029
Echinococcus multilocularis lamin 0.0028 0.0035 0.0035
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0023 0.0025 0.0025
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0023 0.0025 0.0025
Schistosoma mansoni alpha-1 adrenergic receptor 0.018 0.0342 0.0342

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 1000 nM In vitro inhibitory concentration of compound against benzodiazepine receptor from rat cerebral cortex using [3H]- flunitrazepam was evaluated ChEMBL. 8145224
IC50 (binding) > 1000 nM In vitro inhibitory concentration of compound against benzodiazepine receptor from rat cerebral cortex using [3H]- flunitrazepam was evaluated ChEMBL. 8145224

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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