Detailed information for compound 44948

Basic information

Technical information
  • TDR Targets ID: 44948
  • Name: 5-(dithiolan-3-yl)pentanoic acid
  • MW: 206.326 | Formula: C8H14O2S2
  • H donors: 1 H acceptors: 2 LogP: 1.68 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CCCCC1SSCC1
  • InChi: 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
  • InChiKey: AGBQKNBQESQNJD-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 5-(3-dithiolanyl)pentanoic acid
  • 5-(1,2-dithiolan-3-yl)pentanoic acid
  • 5-(dithiolan-3-yl)valeric acid
  • Thioctic Acid
  • berlition
  • 62-46-4
  • 1077-28-7
  • (.+-.)-.alpha.-Lipoic acid
  • (.+-.)-Lipoic acid
  • (.+-.)-Thioctic acid
  • 6,8-Dithiooctanoic acid
  • (RS)-Lipoic acid
  • .alpha.-Liponic acid
  • 1,2-Dithiolane-3-pentanoic acid, (.+-.)-
  • 1,2-Dithiolane-3-valeric acid, (.+-.)-
  • DL-.alpha.-Lipoic acid
  • T1395_SIGMA
  • dl-Lipoic acid
  • MLS000069736
  • Spectrum2_001605
  • KBio3_002335
  • (RS)-.alpha.-Lipoic acid
  • AIDS-030563
  • KBio2_004666
  • 1,2-dithiolane-3-pentanoic acid
  • 5-(1,2-dithiolan-3-yl)-pentanoate
  • LIPOIC-ACID
  • alpha-liponic acid
  • lipoic acid
  • Spectrum5_001298
  • KBio2_007234
  • (+-)-1,2-Dithiolane-3-pentanoic acid
  • 1,2-DITHIOLANE-3-VALERIC ACID, (+-)-
  • 1,2-Dithiolane-3-pentanoic acid, (+-)- (9CI)
  • BRN 0081853
  • DL-1,2-Dithiolan-3-valeriansaeure [German]
  • DL-1,2-Dithiolane 3-valeric acid
  • DL-1,2-Dithiolane-3-valeric acid
  • DL-6,8-Thioctic acid
  • DL-6-Thioctic acid
  • DL-alpha-Lipoic acid
  • EINECS 214-071-2
  • NSC 628502
  • Biletan
  • Rac-lipoate
  • Thioctic acid dl-form
  • dl-Thioctic acid
  • C00725
  • alpha-Lipoic acid
  • 62320_FLUKA
  • NCGC00090872-05
  • Thioctsaeure
  • BSPBio_002835
  • NSC90788
  • SBB003484
  • IDI1_000912
  • KBio2_002098
  • ()-1,2-Dithiolane-3-pentanoic acid
  • ()-alpha-Lipoic acid
  • Lip(S2)
  • T5625_SIAL
  • KBioGR_000853
  • Spectrum4_000217
  • SMR000058198
  • NINDS_000912
  • Thioctansaeure
  • Spectrum3_001188
  • SPECTRUM1503941
  • NCI60_042014
  • DivK1c_000912
  • CHEBI:16494
  • D00086
  • Thioctic acid (JAN)
  • Thiotomin (TN)
  • alpha-Liponsaeure
  • KBio1_000912
  • KBioSS_002098
  • NCGC00090872-02
  • (+/-)-1,2-Dithiolane-3-pentanoic acid
  • NCGC00090872-03
  • AIDS030563
  • NSC628502
  • NSC 90788
  • 1,2-Dithiolane-3-valeric acid
  • SPBio_001609
  • NCGC00090872-01
  • Thiooctic acid
  • Spectrum_001618

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens Bloom syndrome, RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens RecQ helicase-like Starlite/ChEMBL No references
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal Starlite/ChEMBL No references
Trypanosoma brucei gambiense ATP-dependent phosphofructokinase,6-phospho-1-fructokinase No references
Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 Starlite/ChEMBL No references
Homo sapiens l(3)mbt-like 1 (Drosophila) Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens retinoid X receptor, alpha Starlite/ChEMBL No references
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU Starlite/ChEMBL No references
Homo sapiens runt-related transcription factor 1 Starlite/ChEMBL No references
Homo sapiens ubiquitin-like modifier activating enzyme 2 Starlite/ChEMBL No references
Homo sapiens thyroid hormone receptor, beta Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens SUMO1 activating enzyme subunit 1 No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens tyrosyl-DNA phosphodiesterase 1 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens K(lysine) acetyltransferase 2A Starlite/ChEMBL No references
Mus musculus eukaryotic translation initiation factor 4E Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) kappa Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references
Homo sapiens core-binding factor, beta subunit No references
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)(HIV-1) Human immunodeficiency virus type 1 Tat protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania donovani tyrosyl-DNA phosphodiesterase-like protein Get druggable targets OG5_129037 All targets in OG5_129037
Plasmodium berghei histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) ThiF family protein Get druggable targets OG5_127838 All targets in OG5_127838
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase Get druggable targets OG5_131193 All targets in OG5_131193
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma japonicum Thyroid hormone receptor alpha, putative Get druggable targets OG5_134830 All targets in OG5_134830
Trypanosoma brucei gambiense ATP-dependent phosphofructokinase,6-phospho-1-fructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma mansoni sumo-1-activating enzyme E1a Get druggable targets OG5_128859 All targets in OG5_128859
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Babesia bovis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha Get druggable targets OG5_130073 All targets in OG5_130073
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K03259 translation initiation factor eIF-4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Schistosoma japonicum ko:K06062 p300/CBP-associated factor, putative Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 Get druggable targets OG5_127278 All targets in OG5_127278
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus eukaryotic translation initiation factor 4E Get druggable targets OG5_127278 All targets in OG5_127278
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase Get druggable targets OG5_129037 All targets in OG5_129037
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K01113 phosphodiesterase/alkaline phosphatase D [EC3.1.4.1], putative Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase Get druggable targets OG5_129031 All targets in OG5_129031
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania infantum tyrosyl-DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major ubiquitin-activating enzyme-like protein Get druggable targets OG5_127838 All targets in OG5_127838
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Onchocerca volvulus Get druggable targets OG5_133916 All targets in OG5_133916
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Trichomonas vaginalis molybdopterin biosynthesis moeb protein, putative Get druggable targets OG5_127838 All targets in OG5_127838
Candida albicans similar to S. cerevisiae AOS1 (YPR180W) which mediates conjugation of ubiquitin-like Smt3p (sumoylation) to target proteins Get druggable targets OG5_128859 All targets in OG5_128859
Plasmodium yoelii SUMO-1 activating enzyme subunit 1 Get druggable targets OG5_128859 All targets in OG5_128859
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei gambiense eukaryotic translation initiation factor 4e, putative Get druggable targets OG5_127278 All targets in OG5_127278
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Candida albicans phosphofructokinase beta-subunit that can functionally substitute for S. cerevisiae PFK2 (YMR205C) Get druggable targets OG5_126758 All targets in OG5_126758
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium knowlesi histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 Get druggable targets OG5_127781 All targets in OG5_127781
Brugia malayi acetyltransferase, GNAT family protein Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Candida albicans similar to Uba1 (Ub-activating enzyme) Get druggable targets OG5_127838 All targets in OG5_127838
Plasmodium vivax histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K00022 3-hydroxyacyl-CoA dehydrogenase [EC1.1.1.35], putative Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma brucei gambiense DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei gambiense DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Entamoeba histolytica phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma mansoni eukaryotic translation initiation factor 4e Get druggable targets OG5_127278 All targets in OG5_127278
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus granulosus SUMO activating enzyme subunit 1 Get druggable targets OG5_128859 All targets in OG5_128859
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium vivax SUMO-activating enzyme subunit 2, putative Get druggable targets OG5_127838 All targets in OG5_127838
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma mansoni ubiquitin-activating enzyme E1b Get druggable targets OG5_127838 All targets in OG5_127838
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni tyrosyl-DNA phosphodiesterase Get druggable targets OG5_129037 All targets in OG5_129037
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase Get druggable targets OG5_131193 All targets in OG5_131193
Trypanosoma cruzi ubiquitin-activating enzyme, putative Get druggable targets OG5_127838 All targets in OG5_127838
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Candida albicans phosphofructokinase alpha subunit that can functionally substitute for S. cerevisiae PFK1 (YGR240C) Get druggable targets OG5_126758 All targets in OG5_126758
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva translation initiation factor E4, putative Get druggable targets OG5_127278 All targets in OG5_127278
Trypanosoma brucei DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi translation initiation factor 4E Get druggable targets OG5_127278 All targets in OG5_127278
Neospora caninum Bromodomain containing protein, related Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Echinococcus granulosus 6 phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) Get druggable targets OG5_127393 All targets in OG5_127393
Loa Loa (eye worm) phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma japonicum ko:K08524 nuclear receptor, subfamily 2, group B, member 1, putative Get druggable targets OG5_130073 All targets in OG5_130073
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Plasmodium falciparum SUMO-activating enzyme subunit 1 Get druggable targets OG5_128859 All targets in OG5_128859
Leishmania major eukaryotic translation initiation factor eIF-4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal Get druggable targets OG5_134830 All targets in OG5_134830
Brugia malayi 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Entamoeba histolytica ubiquitin-activating enzyme, putative Get druggable targets OG5_127838 All targets in OG5_127838
Leishmania mexicana eukaryotic translation initiation factor-like protein Get druggable targets OG5_127278 All targets in OG5_127278
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania donovani Eukaryotic translation initiation factor 4E-2 Get druggable targets OG5_127278 All targets in OG5_127278
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum ko:K00850 6-phosphofructokinase [EC2.7.1.11], putative Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus granulosus endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Loa Loa (eye worm) acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium hominis scully CG7113-PA Get druggable targets OG5_129031 All targets in OG5_129031
Plasmodium knowlesi SUMO-activating enzyme subunit 1, putative Get druggable targets OG5_128859 All targets in OG5_128859
Leishmania infantum ATP-dependent phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans hypothetical protein Get druggable targets OG5_126758 All targets in OG5_126758
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal Get druggable targets OG5_134830 All targets in OG5_134830
Schistosoma mansoni sumo-1-activating enzyme E1a Get druggable targets OG5_128859 All targets in OG5_128859
Leishmania mexicana eukaryotic translation initiation factor eIF-4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein Get druggable targets OG5_129037 All targets in OG5_129037
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis initiation factor e4 Get druggable targets OG5_127278 All targets in OG5_127278
Giardia lamblia Ubiquitin-activating enzyme E1 1 Get druggable targets OG5_127838 All targets in OG5_127838
Leishmania donovani DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma japonicum ko:K03511 DNA polymerase kappa subunit, putative Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium berghei SUMO-activating enzyme subunit 2, putative Get druggable targets OG5_127838 All targets in OG5_127838
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis thyroid hormone receptor alpha Get druggable targets OG5_134830 All targets in OG5_134830
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma congolense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei gambiense ubiquitin-activating enzyme e1, putative Get druggable targets OG5_127838 All targets in OG5_127838
Entamoeba histolytica phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Leishmania braziliensis DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania braziliensis 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Plasmodium falciparum SUMO-activating enzyme subunit 2 Get druggable targets OG5_127838 All targets in OG5_127838
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania major tyrosyl-DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Leishmania donovani Eukaryotic translation initiation factor 4E-1 Get druggable targets OG5_127278 All targets in OG5_127278
Toxoplasma gondii ThiF family protein Get druggable targets OG5_127838 All targets in OG5_127838
Theileria parva hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis 6 phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal Get druggable targets OG5_126758 All targets in OG5_126758
Leishmania braziliensis eukaryotic translation initiation factor eIF-4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Schistosoma japonicum ko:K08362 nuclear receptor, subfamily 1, group A, member 2, putative Get druggable targets OG5_134830 All targets in OG5_134830
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii histone lysine acetyltransferase GCN5-A Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma japonicum expressed protein Get druggable targets OG5_134830 All targets in OG5_134830
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania infantum 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania mexicana tyrosyl-DNA phosphodiesterase-like protein Get druggable targets OG5_129037 All targets in OG5_129037
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Plasmodium yoelii histone acetyltransferase GCN5-related Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium yoelii related to ubiquitin-activating enzyme homolog UBA2-related Get druggable targets OG5_127838 All targets in OG5_127838
Candida albicans similar to S. cerevisiae AOS1 (YPR180W) which mediates conjugation of ubiquitin-like Smt3p (sumoylation) to target proteins Get druggable targets OG5_128859 All targets in OG5_128859
Leishmania major DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127838 All targets in OG5_127838
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Neospora caninum hypothetical protein Get druggable targets OG5_127278 All targets in OG5_127278
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130415 All targets in OG5_130415
Leishmania major ATP-dependent phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Cryptosporidium parvum translation initiation factor if-4E Get druggable targets OG5_127278 All targets in OG5_127278
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Neospora caninum hypothetical protein Get druggable targets OG5_127781 All targets in OG5_127781
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU Get druggable targets OG5_131193 All targets in OG5_131193
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase Get druggable targets OG5_126758 All targets in OG5_126758
Trichomonas vaginalis phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma brucei DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Cryptosporidium parvum scully CG7113-PA, putative Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Candida albicans mRNA cap-binding protein eIF4E, translation initiation Get druggable targets OG5_127278 All targets in OG5_127278
Trichomonas vaginalis DNA polymerase IV / kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_129037 All targets in OG5_129037
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni thyroid hormone receptor Get druggable targets OG5_134830 All targets in OG5_134830
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Toxoplasma gondii hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Leishmania braziliensis ubiquitin-activating enzyme-like protein Get druggable targets OG5_127838 All targets in OG5_127838
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus granulosus sumo-activating enzyme subunit 2 Get druggable targets OG5_127838 All targets in OG5_127838
Candida albicans phosphofructokinase alpha subunit that can functionally substitute for S. cerevisiae PFK1 (YGR240C) Get druggable targets OG5_126758 All targets in OG5_126758
Leishmania mexicana DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Schistosoma japonicum Lethal(3)malignant brain tumor-like 3 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Candida albicans similar to Uba1 (Ub-activating enzyme) Get druggable targets OG5_127838 All targets in OG5_127838
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU Get druggable targets OG5_131193 All targets in OG5_131193
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis SUMO activating enzyme subunit 2 Get druggable targets OG5_127838 All targets in OG5_127838
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus retinoic acid receptor rxr beta a Get druggable targets OG5_130073 All targets in OG5_130073
Loa Loa (eye worm) translation initiation factor 4E Get druggable targets OG5_127278 All targets in OG5_127278
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii eukaryotic initiation factor-4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Brugia malayi 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma congolense tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Mycobacterium ulcerans 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Mycobacterium ulcerans DNA polymerase IV Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium ulcerans DNA polymerase IV Get druggable targets OG5_127393 All targets in OG5_127393
Neospora caninum AFR138Wp, related Get druggable targets OG5_127838 All targets in OG5_127838
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi ThiF family protein Get druggable targets OG5_128859 All targets in OG5_128859
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei SUMO-activating enzyme subunit 1, putative Get druggable targets OG5_128859 All targets in OG5_128859
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma congolense ATP-dependent 6-phosphofructokinase, glycosomal Get druggable targets OG5_126758 All targets in OG5_126758
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma cruzi ubiquitin-activating enzyme-like protein Get druggable targets OG5_127838 All targets in OG5_127838
Leishmania infantum ubiquitin-activating enzyme-like protein Get druggable targets OG5_127838 All targets in OG5_127838
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania major eukaryotic translation initiation factor-like protein Get druggable targets OG5_127278 All targets in OG5_127278
Candida albicans phosphofructokinase beta-subunit that can functionally substitute for S. cerevisiae PFK2 (YMR205C) Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma japonicum ko:K10684 ubiquitin-like 1-activating enzyme E1 A, putative Get druggable targets OG5_128859 All targets in OG5_128859
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Cryptosporidium parvum GCN5 like acetylase + bromodomain Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania donovani 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani ubiquitin-activating enzyme-like protein Get druggable targets OG5_127838 All targets in OG5_127838
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania mexicana 6-phospho-1-fructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis bromodomain-containing protein, putative Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania mexicana ubiquitin-activating enzyme-like protein Get druggable targets OG5_127838 All targets in OG5_127838
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma cruzi ubiquitin-activating enzyme, putative Get druggable targets OG5_127838 All targets in OG5_127838
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni hypothetical protein Get druggable targets OG5_134830 All targets in OG5_134830
Trichomonas vaginalis phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Trichomonas vaginalis phosphofructokinase, putative Get druggable targets OG5_126758 All targets in OG5_126758
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Cryptosporidium parvum SUMO-1 activating enzyme subunit 2, putative Get druggable targets OG5_127838 All targets in OG5_127838
Entamoeba histolytica acetyltransferase, GNAT family Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Theileria parva histone acetyltransferase Gcn5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Theileria parva ubiquitin-protein ligase, putative Get druggable targets OG5_127838 All targets in OG5_127838
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 Get druggable targets OG5_127278 All targets in OG5_127278
Trypanosoma brucei gambiense DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania donovani ATP-dependent 6-phosphofructokinase, glycosomal Get druggable targets OG5_126758 All targets in OG5_126758
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma congolense Eukaryotic translation initiation factor 4E-1 Get druggable targets OG5_127278 All targets in OG5_127278
Babesia bovis conserved hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Plasmodium vivax ubiquitin activating enzyme, putative Get druggable targets OG5_128859 All targets in OG5_128859
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis eukaryotic translation initiation factor 4E Get druggable targets OG5_127278 All targets in OG5_127278
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal Get druggable targets OG5_126758 All targets in OG5_126758
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis SUMO activating enzyme subunit 1 Get druggable targets OG5_128859 All targets in OG5_128859
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Schistosoma mansoni thyroid hormone receptor Get druggable targets OG5_134830 All targets in OG5_134830
Giardia lamblia Histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi polk-prov protein Get druggable targets OG5_127393 All targets in OG5_127393
Trichomonas vaginalis DNA polymerase eta, putative Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium hominis SUMO-1 activating enzyme subunit 2 Get druggable targets OG5_127838 All targets in OG5_127838
Plasmodium falciparum histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) Get druggable targets OG5_126758 All targets in OG5_126758
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus dna polymerase kappa Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10685 ubiquitin-like 1-activating enzyme E1 B, putative Get druggable targets OG5_127838 All targets in OG5_127838
Babesia bovis ubiquitin-activating enzyme, putative Get druggable targets OG5_127838 All targets in OG5_127838
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis tyrosyl-DNA phosphodiesterase, putative;with=GeneDB:LinJ33_V3.3210 Get druggable targets OG5_129037 All targets in OG5_129037
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Leishmania donovani DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Cryptosporidium parvum tyrosyl-DNA phodphodiesterase 1 (tdp1) Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus multilocularis dna polymerase kappa Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma japonicum Lethal(3)malignant brain tumor-like 4 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Brugia malayi ThiF family protein Get druggable targets OG5_127838 All targets in OG5_127838
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) Get druggable targets OG5_126758 All targets in OG5_126758
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania infantum eukaryotic translation initiation factor-like protein Get druggable targets OG5_127278 All targets in OG5_127278
Echinococcus multilocularis transcription factor Dp 1 Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Plasmodium knowlesi SUMO-activating enzyme subunit 2, putative Get druggable targets OG5_127838 All targets in OG5_127838
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum eukaryotic translation initiation factor eIF-4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Echinococcus granulosus transcription factor Dp 1 Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania braziliensis ATP-dependent phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
Cryptosporidium hominis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni retinoic acid receptor RXR Get druggable targets OG5_130073 All targets in OG5_130073
Schistosoma japonicum Thyroid hormone receptor alpha, putative Get druggable targets OG5_134830 All targets in OG5_134830
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania braziliensis DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative Get druggable targets OG5_127278 All targets in OG5_127278
Toxoplasma gondii histone lysine acetyltransferase GCN5-B Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major eukaryotic translation initiation factor-like Get druggable targets OG5_127278 All targets in OG5_127278
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 Get druggable targets OG5_127278 All targets in OG5_127278
Leishmania mexicana 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma congolense ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127838 All targets in OG5_127838
Giardia lamblia DINP protein human, muc B family Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma mansoni 6-phosphofructokinase Get druggable targets OG5_126758 All targets in OG5_126758
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Giardia lamblia U5 small nuclear ribonucleoprotein 200 kDa helicase, putative RecQ helicase-like 649 aa 521 aa 19.8 %
Brugia malayi photoreceptor-specific nuclear receptor thyroid hormone receptor, beta 461 aa 414 aa 24.6 %
Brugia malayi ecdysteroid receptor retinoid X receptor, alpha 435 aa 352 aa 23.9 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase hydroxysteroid (17-beta) dehydrogenase 10 252 aa 251 aa 24.7 %
Plasmodium falciparum eukaryotic translation initiation factor 4E eukaryotic translation initiation factor 4E 217 aa 188 aa 25.5 %
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Echinococcus multilocularis squamous cell carcinoma antigen Human immunodeficiency virus type 1 Tat protein   86 aa 79 aa 30.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0048 0.016 0.0511
Plasmodium falciparum amino acid transporter, putative 0.008 0.0349 0.8015
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0015 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0148 0.0274
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0088 0.1415
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0091 0.0011
Entamoeba histolytica hypothetical protein 0.0077 0.0335 0.4379
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.033 0.1828 0.3663
Onchocerca volvulus 0.0048 0.016 0.0511
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.033 0.1828 0.3663
Onchocerca volvulus 0.0048 0.016 0.0511
Entamoeba histolytica hypothetical protein 0.0077 0.0335 0.4379
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0048 0.016 0.0311
Brugia malayi ImpB/MucB/SamB family protein 0.0072 0.03 0.0567
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.0066 0.0265 0.0499
Brugia malayi intermediate filament protein 0.0033 0.007 0.0124
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0096 0.1361
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0096 0.0151
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.008 0.0349 0.066
Echinococcus multilocularis serotonin transporter 0.047 0.265 0.2646
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.016 0.0311
Onchocerca volvulus Peroxidasin homolog 0.0032 0.0066 0.0198
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0091 0.0193
Onchocerca volvulus 0.0525 0.2978 0.9817
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 0.016 0.0311
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.0349 0.066
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0134 0.0129
Brugia malayi ThiF family protein 0.0038 0.0104 0.019
Brugia malayi Cytochrome P450 family protein 0.0023 0.0015 0.0018
Loa Loa (eye worm) ThiF family protein 0.0038 0.0104 0.019
Brugia malayi beta-lactamase family protein 0.0036 0.0091 0.0163
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.016 0.0311
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0361 0.0356
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.016 0.0311
Echinococcus multilocularis neuropeptide receptor A26 0.0048 0.016 0.0155
Loa Loa (eye worm) neuropeptide F receptor 0.0048 0.016 0.0298
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0287 0.0541
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0096 0.1626
Loa Loa (eye worm) animal heme peroxidase 0.0032 0.0066 0.0115
Brugia malayi mbt repeat family protein 0.0058 0.0218 0.0408
Trichomonas vaginalis aldehyde oxidase, putative 0.0168 0.0869 0.2704
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0091 0.0176
Echinococcus granulosus dna polymerase eta 0.0072 0.03 0.0592
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0046 0.0148 0.0287
Echinococcus multilocularis G protein coupled receptor 139 0.0048 0.016 0.0155
Loa Loa (eye worm) neuropeptide F receptor 0.0048 0.016 0.0298
Loa Loa (eye worm) carboxylesterase 0.0082 0.0361 0.0684
Echinococcus granulosus hypothetical protein 0.0048 0.016 0.0311
Brugia malayi nuclear receptor NHR-88 0.0046 0.0148 0.0274
Loa Loa (eye worm) hypothetical protein 0.008 0.0349 0.066
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.012 0.0589 0.1294
Echinococcus multilocularis GPCR, family 2 0.0286 0.1564 0.1559
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0042 0.0124 0.2005
Echinococcus multilocularis neuropeptide receptor 0.0048 0.016 0.0155
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0101 0.0193
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0048 0.016 0.0155
Onchocerca volvulus 0.0048 0.016 0.0511
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.016 0.0155
Echinococcus granulosus sodium and chloride dependent glycine 0.008 0.0349 0.069
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0218 0.0408
Brugia malayi polk-prov protein 0.0045 0.0142 0.0263
Schistosoma mansoni hypothetical protein 0.0358 0.1988 0.3985
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0142 0.0287
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0653 0.1955
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0096 0.0148
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0287 0.0681
Echinococcus granulosus histone lysine methyltransferase setb 0.0087 0.039 0.0774
Onchocerca volvulus 0.0032 0.0066 0.0198
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0096 0.0182
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.0046 0.0148 0.0274
Schistosoma mansoni ap endonuclease 0.0037 0.0096 0.0181
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0091 0.0171
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0046 0.0148 0.0274
Leishmania major DNA polymerase kappa, putative 0.0049 0.0166 0.034
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0048 0.016 0.0511
Schistosoma mansoni biogenic amine receptor 0.0048 0.016 0.0311
Echinococcus granulosus peptide allatostatin:somatostatin 0.0048 0.016 0.0311
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0042 0.0124 0.0126
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0215 0.021
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0035 0.0082 0.133
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.008 0.0349 0.069
Brugia malayi Latrophilin receptor protein 2 0.0286 0.1564 0.2997
Brugia malayi putative neuropeptide receptor NPR1 0.0048 0.016 0.0298
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0044 0.0065
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.016 0.0311
Schistosoma mansoni sodium-dependent amino acid transporter 0.008 0.0349 0.069
Loa Loa (eye worm) beta-lactamase 0.0036 0.0091 0.0163
Trichomonas vaginalis bromodomain-containing protein, putative 0.0054 0.0199 0.0385
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0048 0.016 0.0298
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0035 0.0082 0.0077
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0035 0.0082 0.0077
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0178 0.0928 0.0922
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0589 0.1173
Onchocerca volvulus 0.0048 0.016 0.0511
Schistosoma mansoni neuropeptide f receptor 76f 0.0048 0.016 0.0311
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0042 0.0124 0.0126
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0096 0.0029
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0168 0.0869 0.2704
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0091 0.0085
Plasmodium falciparum transporter, putative 0.008 0.0349 0.8015
Brugia malayi Calcitonin receptor-like protein seb-1 0.0903 0.5207 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0073 0.0308 0.0764
Echinococcus granulosus neuropeptide receptor 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0396 0.2213 0.4245
Brugia malayi Melatonin receptor type 1A 0.0048 0.016 0.0298
Echinococcus granulosus ecdysone induced protein 78C 0.0046 0.0148 0.0287
Schistosoma mansoni RAR-like nuclear receptor 0.0046 0.0148 0.0287
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Echinococcus granulosus tachykinin peptides receptor 99D 0.0048 0.016 0.0311
Brugia malayi Muscleblind-like protein 0.0149 0.0759 0.1448
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.0349 0.5641
Loa Loa (eye worm) transcription factor SMAD2 0.0375 0.2091 0.401
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0048 0.016 0.0155
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.016 0.0155
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0287 0.0697
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0058 0.0222 0.0434
Schistosoma mansoni neuropeptide receptor 0.0048 0.016 0.0311
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0048 0.016 0.0311
Mycobacterium ulcerans hypothetical protein 0.0024 0.0022 0.0017
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0101 0.0193
Loa Loa (eye worm) RNA binding protein 0.0281 0.1534 0.2939
Loa Loa (eye worm) blistered cuticle protein 3 0.0032 0.0066 0.0115
Echinococcus granulosus orexin receptor type 2 0.0048 0.016 0.0311
Brugia malayi Inositol-1 0.0037 0.0096 0.0174
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0093 0.0424 1
Schistosoma mansoni opsin-like receptor 0.0048 0.016 0.0311
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0653 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0048 0.016 0.0298
Echinococcus granulosus Smad4 0.0026 0.0029 0.0047
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0096 0.1361
Loa Loa (eye worm) steroid hormone receptor 0.0046 0.0148 0.0274
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0684 0.3914 1
Loa Loa (eye worm) runx1 0.0067 0.0274 0.0516
Schistosoma mansoni neuropeptide receptor 0.0048 0.016 0.0311
Brugia malayi GnHR receptor homolog 0.0048 0.016 0.0298
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni hypothetical protein 0.0077 0.0335 0.0662
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0048 0.016 0.0298
Schistosoma mansoni Smad4 0.0026 0.0029 0.0047
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni hypothetical protein 0.0048 0.016 0.0311
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.0732 0.1825
Brugia malayi Bromodomain containing protein 0.0051 0.0176 0.0328
Mycobacterium ulcerans endonuclease IV 0.0093 0.0424 0.1049
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0042 0.0124 0.0238
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0265 0.0499
Schistosoma mansoni lamin 0.0033 0.007 0.013
Echinococcus granulosus muscleblind protein 0.0149 0.0759 0.1514
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0082 0.0361 0.0715
Onchocerca volvulus 0.0036 0.0091 0.028
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0048 0.016 0.0155
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0091 0.0193
Schistosoma mansoni inositol monophosphatase 0.0037 0.0096 0.0182
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0462 0.2602 0.4991
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0046 0.0148 0.0274
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0215 0.0421
Brugia malayi Pre-SET motif family protein 0.0462 0.2602 0.4991
Schistosoma mansoni zinc finger protein 0.0028 0.0043 0.0075
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0048 0.016 0.0311
Brugia malayi beta-lactamase 0.0036 0.0091 0.0163
Loa Loa (eye worm) hypothetical protein 0.0056 0.0207 0.0388
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0589 0.1471
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0349 0.0752
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0032 0.0067 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Onchocerca volvulus Neuropeptide F receptor homolog 0.0048 0.016 0.0511
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0038 0.0104 0.0201
Echinococcus granulosus smad 0.0026 0.0029 0.0047
Mycobacterium ulcerans hypothetical protein 0.0036 0.0091 0.0193
Onchocerca volvulus 0.0036 0.0091 0.028
Echinococcus multilocularis g-protein coupled receptor 0.0048 0.016 0.0155
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0684 0.3914 1
Echinococcus granulosus acetylcholinesterase 0.0082 0.0361 0.0715
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0093 0.0424 0.0805
Schistosoma mansoni lipoxygenase 0.0084 0.0371 0.0734
Onchocerca volvulus 0.0535 0.3033 1
Brugia malayi Dopamine receptor protein 1 0.0048 0.016 0.0298
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.016 0.0311
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0265 0.0522
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.0647 0.1605
Toxoplasma gondii hypothetical protein 0.0058 0.0222 0.3585
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0044 0.0713
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni biogenic amine (5HT) receptor 0.0299 0.1641 0.3289
Loa Loa (eye worm) solute carrier family 6 member 4 0.047 0.265 0.5084
Schistosoma mansoni neuropeptide receptor 0.0048 0.016 0.0311
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.0882 0.1761
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0066 0.0269 0.4349
Echinococcus multilocularis bloom syndrome protein 0.005 0.0172 0.0166
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0157 0.8895
Brugia malayi TAR-binding protein 0.0281 0.1534 0.2939
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0053 0.019 0.0371
Onchocerca volvulus 0.0048 0.016 0.0511
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0046 0.0148 0.0274
Loa Loa (eye worm) G-protein coupled receptor 0.0048 0.016 0.0298
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0096 0.0182
Schistosoma mansoni hypothetical protein 0.0025 0.0025 0.0039
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0112 0.0204
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0096 0.0182
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.0653 0.2431
Brugia malayi neuropeptide F receptor 0.0048 0.016 0.0298
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0049 0.0794
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.0163
Loa Loa (eye worm) hypothetical protein 0.0024 0.0021 0.0029
Mycobacterium ulcerans DNA polymerase IV 0.0073 0.0308 0.0752
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.0647 0.1605
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0048 0.016 0.0311
Schistosoma mansoni smad1 5 8 and 0.0026 0.0029 0.0047
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0046 0.0148 0.0143
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0038 0.0104 0.1583
Schistosoma mansoni hypothetical protein 0.0618 0.3521 0.7068
Loa Loa (eye worm) animal heme peroxidase 0.0032 0.0066 0.0115
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0091 0.017
Echinococcus granulosus neuropeptide Y receptor 0.0048 0.016 0.0311
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0091 0.0171
Echinococcus multilocularis neuropeptides capa receptor 0.0048 0.016 0.0155
Brugia malayi hypothetical protein 0.0036 0.0089 0.0161
Onchocerca volvulus 0.0033 0.007 0.0214
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Onchocerca volvulus 0.0048 0.016 0.0511
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.0349 0.0343
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0119 0.0249
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0091 0.0163
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.0349 0.066
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0088 0.1142
Brugia malayi hypothetical protein 0.0032 0.0066 0.0115
Schistosoma mansoni amine GPCR 0.0448 0.252 0.5055
Loa Loa (eye worm) hypothetical protein 0.0535 0.3033 0.5821
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0265 0.0522
Schistosoma mansoni lipoxygenase 0.0119 0.0583 0.1161
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0015 0.0018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.016 0.0155
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0091 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Echinococcus granulosus GPCR family 2 0.0286 0.1564 0.3134
Onchocerca volvulus 0.0048 0.016 0.0511
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0653 0.1955
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 0.016 0.0311
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.008 0.0349 0.069
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0287 0.0697
Echinococcus granulosus dna polymerase kappa 0.0073 0.0308 0.0608
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.0349 0.0689
Schistosoma mansoni DNA helicase recq5 0.0035 0.0082 0.0154
Echinococcus multilocularis sodium and chloride dependent glycine 0.008 0.0349 0.0343
Schistosoma mansoni hypothetical protein 0.0865 0.4979 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.016 0.0311
Brugia malayi Carboxylesterase family protein 0.0082 0.0361 0.0684
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.008 0.0349 0.066
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0058 0.0222 0.4671
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0269 0.0529
Loa Loa (eye worm) hypothetical protein 0.0053 0.0194 0.0362
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0181 0.0374
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.008 0.0349 0.0343
Echinococcus granulosus neuropeptide s receptor 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0234 0.1261 0.2524
Schistosoma mansoni steroid hormone receptor ad4bp 0.0046 0.0148 0.0287
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Brugia malayi hypothetical protein 0.0535 0.3033 0.5821
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0048 0.016 0.0155
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.0349 0.069
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0077 0.0137
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0046 0.0148 0.0287
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.0163
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.0218 0.0427
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0064 0.0255 0.05
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0119 0.0228
Leishmania major hypothetical protein, conserved 0.0028 0.0044 0.0065
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Onchocerca volvulus 0.0036 0.0091 0.028
Brugia malayi photoreceptor-specific nuclear receptor 0.0046 0.0148 0.0274
Brugia malayi phosphofructokinase 0.0131 0.0653 0.1244
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.012 0.0589 0.1173
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0286 0.1564 0.2997
Echinococcus granulosus G protein coupled receptor 139 0.0048 0.016 0.0311
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0096 0.0182
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0029 0.0045
Brugia malayi steroid hormone receptor 0.0046 0.0148 0.0274
Brugia malayi Pre-SET motif family protein 0.0066 0.0269 0.0506
Echinococcus multilocularis allatostatin A receptor 0.0048 0.016 0.0155
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0903 0.5207 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0046 0.0148 0.0143
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.016 0.0311
Schistosoma mansoni hypothetical protein 0.0286 0.1564 0.3134
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.0163
Plasmodium vivax hypothetical protein, conserved 0.008 0.0349 0.8015
Brugia malayi sulfakinin receptor protein 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.008 0.0349 0.066
Brugia malayi hypothetical protein 0.0024 0.0021 0.0029
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0361 0.0356
Loa Loa (eye worm) animal heme peroxidase 0.0032 0.0066 0.0115
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0134 0.0259
Echinococcus granulosus neuropeptide receptor 0.0048 0.016 0.0311
Onchocerca volvulus 0.008 0.0349 0.1133
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.008 0.0349 0.066
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0215 0.0496
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0091 0.0011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0082 0.0361 0.0684
Schistosoma mansoni opsin-like receptor 0.0048 0.016 0.0311
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Onchocerca volvulus 0.0033 0.007 0.0214
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.0218 0.0702
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.004 0.0112 0.1809
Onchocerca volvulus Bile acid receptor homolog 0.0046 0.0148 0.0471
Loa Loa (eye worm) hypothetical protein 0.0024 0.0021 0.0029
Brugia malayi G protein-coupled receptor 0.0048 0.016 0.0298
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0048 0.016 0.0311
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0096 0.0173
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0046 0.0148 0.0274
Brugia malayi acetyltransferase, GNAT family protein 0.0178 0.0928 0.1773
Brugia malayi hypothetical protein 0.0077 0.0335 0.0633
Treponema pallidum quinoline 2-oxidoreductase 0.0027 0.0036 0.0093
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Brugia malayi neuropeptide F receptor 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.0149 0.0759 0.1448
Loa Loa (eye worm) hypothetical protein 0.0045 0.0142 0.0263
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.008 0.0349 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0046 0.0148 0.0274
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0057 0.0213 0.0507
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.0163
Echinococcus multilocularis lamin dm0 0.0033 0.007 0.0065
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0281 0.1534 0.2939
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Leishmania major trypanothione reductase 0.0057 0.0215 0.0451
Trichomonas vaginalis DNA helicase recq1, putative 0.005 0.0172 0.0291
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.0163
Schistosoma mansoni neuropeptide F-like receptor 0.0048 0.016 0.0311
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.007 0.0124
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0091 0.0176
Echinococcus granulosus biogenic amine 5HT receptor 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0024 0.0021 0.0029
Echinococcus multilocularis lamin 0.0033 0.007 0.0065
Echinococcus multilocularis G-protein coupled receptor, putative 0.0048 0.016 0.0155
Onchocerca volvulus 0.0048 0.016 0.0511
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0024 0.0021 0.0031
Mycobacterium tuberculosis Probable reductase 0.013 0.0647 0.1605
Loa Loa (eye worm) glutathione reductase 0.0057 0.0215 0.0403
Onchocerca volvulus 0.0032 0.0066 0.0198
Loa Loa (eye worm) glutaminase 2 0.0317 0.1747 0.3348
Echinococcus granulosus bloom syndrome protein 0.005 0.0172 0.0333
Loa Loa (eye worm) norepinephrine transporter 0.047 0.265 0.5084
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.008 0.0349 0.066
Echinococcus multilocularis sex peptide receptor 0.0048 0.016 0.0155
Schistosoma mansoni smad1 5 8 and 0.0026 0.0029 0.0047
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.0349 0.4619
Schistosoma mansoni sodium/chloride dependent transporter 0.008 0.0349 0.069
Schistosoma mansoni smad 0.0026 0.0029 0.0047
Echinococcus granulosus g-protein coupled receptor 0.0048 0.016 0.0311
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0088 0.1142
Mycobacterium tuberculosis Conserved protein 0.0036 0.0091 0.0176
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.039 0.0774
Brugia malayi Smad1 0.0026 0.0029 0.0045
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.0349 0.066
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.008 0.0349 0.0343
Echinococcus multilocularis serotonin receptor 0.0299 0.1641 0.1637
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0046 0.0148 0.0274
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0096 0.0182
Echinococcus multilocularis geminin 0.0865 0.4979 0.4976
Brugia malayi Cytochrome P450 family protein 0.0034 0.0077 0.0137
Echinococcus multilocularis tar DNA binding protein 0.0281 0.1534 0.1529
Loa Loa (eye worm) hypothetical protein 0.008 0.0349 0.066
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0215 0.0403
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0076 0.0329 0.0323
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0287 0.0613
Onchocerca volvulus 0.0032 0.0066 0.0198
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni amine GPCR 0.0048 0.016 0.0311
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0286 0.1564 0.1559
Toxoplasma gondii ABC1 family protein 0.0036 0.0091 0.1465
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0046 0.0148 0.0274
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.0653 0.1301
Echinococcus granulosus sodium and chloride dependent glycine 0.008 0.0349 0.069
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0079 0.0345 0.0847
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0091 0.017
Trypanosoma brucei unspecified product 0.0065 0.0261 0.0555
Loa Loa (eye worm) hypothetical protein 0.0058 0.0222 0.0415
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0058 0.0222 0.0434
Trypanosoma brucei unspecified product 0.0028 0.0044 0.0065
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0048 0.016 0.0298
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0096 0.0181
Brugia malayi latrophilin 2 splice variant baaae 0.0618 0.3521 0.6758
Schistosoma mansoni biogenic amine receptor 0.0048 0.016 0.0311
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0024 0.0022 0.0017
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0043 0.0134 0.2174
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.039 0.0774
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0025 0.0038
Loa Loa (eye worm) hypothetical protein 0.0085 0.0382 0.0724
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.016 0.0311
Schistosoma mansoni alpha-1 adrenergic receptor 0.0048 0.016 0.0311
Schistosoma mansoni hypothetical protein 0.0286 0.1564 0.3134
Loa Loa (eye worm) hypothetical protein 0.0775 0.4447 0.854
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni amine GPCR 0.0048 0.016 0.0311
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0048 0.016 0.0311
Echinococcus multilocularis musashi 0.0033 0.007 0.0065
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0046 0.0148 0.0287
Loa Loa (eye worm) hypothetical protein 0.0046 0.0148 0.0274
Brugia malayi MH1 domain containing protein 0.0026 0.0029 0.0045
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0024 0.0022 0.0054
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.008 0.0349 0.069
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0042 0.0124 0.0646
Onchocerca volvulus 0.0048 0.016 0.0511
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0148 0.0287
Brugia malayi Sodium:neurotransmitter symporter family protein 0.047 0.265 0.5084
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0653 0.1244
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0287 0.0281
Schistosoma mansoni adenoreceptor 0.0048 0.016 0.0311
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0134 0.0269
Treponema pallidum sodium- and chloride- dependent transporter 0.047 0.265 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0024 0.0021 0.0029
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.0732 0.1825
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0021 0.0029
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0119 0.0555
Entamoeba histolytica hypothetical protein 0.0077 0.0335 0.4379
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0178 0.0928 0.1854
Brugia malayi Dopamine receptor protein 2 0.0048 0.016 0.0298
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0653 0.1955
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0896 0.1988
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0096 0.019
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Echinococcus granulosus uncharacterized sodium dependent transporter 0.008 0.0349 0.069
Loa Loa (eye worm) MH2 domain-containing protein 0.0375 0.2091 0.401
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0112 0.1783
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Schistosoma mansoni thyroid hormone receptor 0.0198 0.1045 0.209
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0046 0.0148 0.0143
Loa Loa (eye worm) hypothetical protein 0.0046 0.0148 0.0274
Onchocerca volvulus 0.0048 0.016 0.0511
Loa Loa (eye worm) inositol-1 0.0037 0.0096 0.0174
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0039 0.0033
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0035 0.0082 0.0154
Loa Loa (eye worm) hypothetical protein 0.0299 0.1641 0.3145
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.007 0.0124
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.0896 0.1988
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0066 0.0269 0.0263
Echinococcus multilocularis carboxylesterase 5A 0.0082 0.0361 0.0356
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0165 0.085 0.1699
Echinococcus multilocularis dro:myosuppressin receptor 0.0048 0.016 0.0155
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0119 0.0583 0.1161
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0046 0.0148 0.0274
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0066 0.0269 0.0529
Schistosoma mansoni sodium/chloride dependent transporter 0.008 0.0349 0.069
Brugia malayi glutaminase DH11.1 0.0317 0.1747 0.3348
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0032 0.0067 0.0134
Brugia malayi larval opioid receptor 0.0048 0.016 0.0298
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.008 0.0349 0.7759
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.0896 0.1988
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.0163
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0048 0.016 0.0311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.016 0.0155
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0049 0.0166 0.037
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0091 0.0176
Treponema pallidum licC protein (licC) 0.0125 0.0618 0.2302
Trypanosoma cruzi DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Brugia malayi hypothetical protein 0.0028 0.0044 0.0074
Mycobacterium ulcerans hypothetical protein 0.0192 0.1011 0.2555
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0038 0.0104 0.0198
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0048 0.016 0.0298
Echinococcus granulosus neuropeptides capa receptor 0.0048 0.016 0.0311
Echinococcus multilocularis serotonin receptor 0.0299 0.1641 0.1637
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0308 0.0661
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni tar DNA-binding protein 0.0281 0.1534 0.3073
Brugia malayi Cytochrome P450 family protein 0.0023 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Brugia malayi MH2 domain containing protein 0.0026 0.0029 0.0045
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0215 0.4499
Brugia malayi Serotonin receptor 0.0048 0.016 0.0298
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.0349 0.069
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0042 0.0124 0.0118
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.0349 0.069
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0218 0.0427
Onchocerca volvulus Chorion peroxidase homolog 0.0032 0.0066 0.0198
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0349 0.0752
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0148 0.0143
Trypanosoma brucei trypanothione reductase 0.0057 0.0215 0.0451
Schistosoma mansoni neuropeptide receptor 0.0048 0.016 0.0311
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0046 0.0152 0.0281
Loa Loa (eye worm) melatonin receptor type 1A 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Echinococcus multilocularis neuropeptide s receptor 0.0048 0.016 0.0155
Echinococcus granulosus neuropeptide receptor A26 0.0048 0.016 0.0311
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0088 0.1142
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.008 0.0349 0.066
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0048 0.016 0.0155
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0335 0.0329
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0038 0.0104 0.0099
Plasmodium vivax amine transporter, putative 0.008 0.0349 0.8015
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0112 0.1783
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0046 0.0148 0.0287
Mycobacterium ulcerans epimerase 0.0024 0.0022 0.0017
Schistosoma mansoni thyroid hormone receptor 0.0198 0.1045 0.209
Echinococcus granulosus geminin 0.0865 0.4979 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0021 0.0029
Brugia malayi MH2 domain containing protein 0.0375 0.2091 0.401
Schistosoma mansoni hypothetical protein 0.0048 0.016 0.0311
Trichomonas vaginalis DNA helicase recq, putative 0.005 0.0172 0.0291
Mycobacterium tuberculosis Conserved protein 0.0036 0.0091 0.0176
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Loa Loa (eye worm) TAR-binding protein 0.0281 0.1534 0.2939
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0058 0.0222 0.0216
Entamoeba histolytica recQ family helicase, putative 0.0038 0.0101 0.0234
Schistosoma mansoni hypothetical protein 0.0048 0.016 0.0311
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.0349 0.5641
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 0.016 0.0311
Brugia malayi nuclear receptor RXR 0.0024 0.0021 0.0029
Loa Loa (eye worm) hypothetical protein 0.0535 0.3033 0.5821
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0653 0.1301
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Schistosoma mansoni glutaminase 0.0317 0.1747 0.3501
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0091 0.0176
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0042 0.0124 0.0245
Echinococcus multilocularis smad 0.0026 0.0029 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Echinococcus multilocularis FTZ F1 alpha 0.0046 0.0148 0.0143
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0148 0.0287
Schistosoma mansoni bromodomain containing protein 0.0081 0.0354 0.0701
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0029 0.0045
Brugia malayi MH1 domain containing protein 0.0026 0.0029 0.0045
Loa Loa (eye worm) hypothetical protein 0.047 0.265 0.5084
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0096 0.003
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0684 0.3914 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0048 0.016 0.0298
Echinococcus granulosus dro:myosuppressin receptor 0.0048 0.016 0.0311
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0653 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.016 0.0311
Mycobacterium ulcerans lipase LipD 0.0036 0.0091 0.0193
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0286 0.1564 0.3134
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0287 0.0566
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0046 0.0148 0.0274
Brugia malayi G-protein coupled receptor 0.0048 0.016 0.0298
Leishmania major eukaryotic translation initiation factor-like 0.0042 0.0124 0.0245
Trypanosoma brucei DNA polymerase IV, putative 0.0065 0.0261 0.0555
Loa Loa (eye worm) hypothetical protein 0.0046 0.0148 0.0274
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0042 0.0124 0.0126
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0048 0.016 0.0311
Brugia malayi Blistered cuticle protein 3 0.0032 0.0066 0.0115
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0021 0.0029
Schistosoma mansoni retinoic acid receptor RXR 0.0165 0.085 0.1699
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.008 0.0349 0.066
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0589 0.1471
Brugia malayi Bloom's syndrome protein homolog 0.005 0.0172 0.0319
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.016 0.0311
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0088 0.1142
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0096 0.0207
Echinococcus granulosus g protein coupled receptor 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.004 0.0112 0.0204
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0096 0.009
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.0349 0.0689
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0151 0.0291
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0035 0.0082 0.0147
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0218 0.0427
Plasmodium vivax SET domain protein, putative 0.0066 0.0269 0.5914
Toxoplasma gondii hypothetical protein 0.0059 0.0225 0.3643
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0035 0.0082 0.1003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0021 0.0031
Onchocerca volvulus 0.008 0.0349 0.1133
Plasmodium falciparum glutathione reductase 0.0057 0.0215 0.4499
Loa Loa (eye worm) RecQ helicase 0.005 0.0172 0.0319
Trypanosoma brucei DNA polymerase eta, putative 0.0072 0.03 0.0643
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.0653 1
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.0589 0.1173
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0054 0.0199 0.3215
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.0349 0.069
Echinococcus granulosus uncharacterized sodium dependent transporter 0.008 0.0349 0.069
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0091 0.017
Schistosoma mansoni opsin-like receptor 0.0048 0.016 0.0311
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0101 0.0193
Loa Loa (eye worm) TYRA-2 protein 0.0048 0.016 0.0298
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.0647 0.1605
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0653 0.1438
Echinococcus granulosus fmrfamide receptor 0.0048 0.016 0.0311
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.016 0.0311
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0048 0.016 0.0311
Schistosoma mansoni DNA polymerase eta 0.0072 0.03 0.0592
Trypanosoma brucei unspecified product 0.0028 0.0044 0.0065
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0168 0.0869 0.2704
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0096 0.0001
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0054 0.0199 0.4069
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0042 0.0124 0.0646
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.0349 0.0659
Brugia malayi Animal haem peroxidase family protein 0.0032 0.0066 0.0115
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.016 0.0311
Brugia malayi Thioredoxin reductase 0.0057 0.0215 0.0403
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.0308 0.0661
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0038 0.0104 0.0198
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.016 0.0155
Brugia malayi translation initiation factor 4E 0.0042 0.0124 0.0227
Brugia malayi follicle stimulating hormone receptor 0.0048 0.016 0.0298
Brugia malayi RNA binding protein 0.0281 0.1534 0.2939
Brugia malayi nuclear hormone receptor 0.0046 0.0148 0.0274
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0046 0.0148 0.0274
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0119 0.0218
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0091 0.0171
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.0349 0.0659
Onchocerca volvulus 0.008 0.0349 0.1133
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Brugia malayi Tachykinin-like peptides receptor 99D 0.0048 0.016 0.0298
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0148 0.0287
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0335 0.0662
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0049 0.0166 0.034
Echinococcus multilocularis thyroid hormone receptor alpha 0.0198 0.1045 0.104
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0151 0.0145
Schistosoma mansoni hypothetical protein 0.0152 0.0775 0.1547
Schistosoma mansoni DNA helicase recq1 0.0035 0.0082 0.0154
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0048 0.016 0.0155
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.0218 0.0427
Echinococcus granulosus neuropeptide Y receptor 0.0048 0.016 0.0311
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0046 0.0148 0.0287
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0042 0.0124 0.0245
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.0647 0.1605
Loa Loa (eye worm) hypothetical protein 0.0618 0.3521 0.6758
Leishmania major eukaryotic translation initiation factor-like protein 0.0042 0.0124 0.0245
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0286 0.1564 0.3134
Loa Loa (eye worm) glutaminase 0.0317 0.1747 0.3348
Mycobacterium tuberculosis Possible penicillin-binding protein 0.023 0.1234 0.3115
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.0653 0.1955
Onchocerca volvulus 0.0048 0.016 0.0511
Echinococcus multilocularis Smad4 0.0026 0.0029 0.0023
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0044 0.0065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.016 0.0155
Echinococcus granulosus carboxylesterase 5A 0.0082 0.0361 0.0715
Loa Loa (eye worm) intermediate filament protein 0.0033 0.007 0.0124
Onchocerca volvulus 0.0046 0.0148 0.0471
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0091 0.0011
Brugia malayi Animal haem peroxidase family protein 0.0032 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0072 0.03 0.0567
Loa Loa (eye worm) hypothetical protein 0.0046 0.0148 0.0274
Echinococcus granulosus intermediate filament protein 0.0033 0.007 0.013
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.0653 0.1635
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0046 0.0148 0.0274
Schistosoma mansoni hypothetical protein 0.0286 0.1564 0.3134
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0091 0.0171
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.0653 0.0647
Echinococcus multilocularis muscleblind protein 1 0.0149 0.0759 0.0754
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Loa Loa (eye worm) phosphofructokinase 0.0131 0.0653 0.1244
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.033 0.1828 0.3663
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.016 0.0311
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0091 0.0171
Loa Loa (eye worm) Smad1 0.0026 0.0029 0.0045
Echinococcus granulosus peroxidasin 0.0032 0.0066 0.012
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0096 0.0029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 0.016 0.0155
Brugia malayi 6-phosphofructokinase 0.0131 0.0653 0.1244
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0096 0.003
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0029 0.0047
Brugia malayi G protein-coupled receptor F59B2.13 0.0048 0.016 0.0298
Schistosoma mansoni inositol monophosphatase 0.0037 0.0096 0.0182
Brugia malayi glutathione reductase 0.0057 0.0215 0.0403
Onchocerca volvulus Protein ultraspiracle homolog 0.0046 0.0148 0.0471
Giardia lamblia DINP protein human, muc B family 0.0049 0.0166 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0072 0.0127
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0035 0.0082 0.0147
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0287 0.0566
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0141 0.0708 0.0703
Loa Loa (eye worm) hypothetical protein 0.0087 0.039 0.074
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0118
Schistosoma mansoni hypothetical protein 0.0048 0.016 0.0311
Leishmania major ubiquitin-activating enzyme-like protein 0.0038 0.0104 0.0201
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0234 0.1261 0.1256
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0096 0.0173
Plasmodium vivax glutathione reductase, putative 0.0057 0.0215 0.4499
Leishmania major DNA polymerase eta, putative 0.0072 0.03 0.0643
Echinococcus multilocularis g protein coupled receptor 0.0048 0.016 0.0155
Brugia malayi ecdysteroid receptor 0.0046 0.0148 0.0274
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0087 0.039 0.0385
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0096 0.009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0046 0.0148 0.0274
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.033 0.1828 0.1823
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0046 0.0148 0.0471
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0265 0.0522
Schistosoma mansoni smad1 5 8 and 0.0026 0.0029 0.0047
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0093 0.0424 1
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0038 0.0104 0.1583
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0091 0.0176
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0035 0.0082 0.133
Echinococcus multilocularis neuropeptides capa receptor 0.0048 0.016 0.0155
Schistosoma mansoni hypothetical protein 0.0865 0.4979 1
Echinococcus multilocularis g protein coupled receptor 0.0048 0.016 0.0155
Echinococcus multilocularis Protein lozenge 0.0067 0.0274 0.0269
Loa Loa (eye worm) hypothetical protein 0.0058 0.0218 0.0408
Brugia malayi hypothetical protein 0.0024 0.0021 0.0029
Trypanosoma cruzi DNA polymerase eta, putative 0.0072 0.03 0.0643
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0181 0.0374
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0073 0.0132
Schistosoma mansoni histamine h1 receptor 0.0048 0.016 0.0311
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0032 0.0067 0.0134
Brugia malayi hypothetical protein 0.008 0.0349 0.066
Schistosoma mansoni intermediate filament proteins 0.0033 0.007 0.013
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.0647 0.1605
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Toxoplasma gondii thioredoxin reductase 0.0057 0.0215 0.3479
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0046 0.0148 0.0274
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0308 0.0661
Brugia malayi AKH receptor 0.0048 0.016 0.0298
Echinococcus granulosus tar DNA binding protein 0.0281 0.1534 0.3073
Echinococcus granulosus biogenic amine 5HT receptor 0.0299 0.1641 0.3289
Toxoplasma gondii aldehyde dehydrogenase 0.012 0.0589 0.9523
Schistosoma mansoni peroxidasin 0.0032 0.0066 0.012
Loa Loa (eye worm) acetyltransferase 0.0178 0.0928 0.1773
Brugia malayi Dopamine receptor 0.0048 0.016 0.0298
Toxoplasma gondii hypothetical protein 0.008 0.0349 0.5641
Schistosoma mansoni hypothetical protein 0.0286 0.1564 0.3134
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.0732 0.1825
Chlamydia trachomatis endonuclease IV 0.0093 0.0424 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0142 0.0287
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0091 0.0171
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.203 0.4545
Echinococcus multilocularis sodium and chloride dependent glycine 0.008 0.0349 0.0343
Echinococcus multilocularis fmrfamide receptor 0.0048 0.016 0.0155
Loa Loa (eye worm) hypothetical protein 0.0046 0.0148 0.0274
Echinococcus granulosus g protein coupled receptor 0.0048 0.016 0.0311
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0096 0.0207
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.0349 0.0752
Schistosoma mansoni ap endonuclease 0.0037 0.0096 0.0181
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0903 0.5207 1
Brugia malayi G-protein coupled receptor 0.0048 0.016 0.0298
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.008 0.0349 0.069
Toxoplasma gondii ThiF family protein 0.0038 0.0104 0.1686
Mycobacterium ulcerans glutaminase 0.0317 0.1747 0.4442
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.203 0.4545
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0042 0.0124 0.0245
Mycobacterium ulcerans DNA polymerase IV 0.0073 0.0308 0.0752
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0042 0.0124 0.0245
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0119 0.0113
Echinococcus multilocularis somatostatin receptor 0.0048 0.016 0.0155
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0048 0.016 0.0298
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0029 0.0047
Trichomonas vaginalis set domain proteins, putative 0.0525 0.2978 1
Trichomonas vaginalis DNA helicase recq, putative 0.0038 0.0101 0.0046
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0079 0.0345 0.0831
Entamoeba histolytica hypothetical protein 0.0077 0.0335 0.4379
Toxoplasma gondii hypothetical protein 0.008 0.0349 0.5641
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0091 0.0011
Echinococcus granulosus 7TM GPCR rhodopsin 0.0048 0.016 0.0311
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0265 0.026
Brugia malayi ThiF family protein 0.0058 0.0222 0.0415
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0088 0.1415
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0048 0.016 0.0155
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.0218 0.0213
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0096 0.0182
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0091 0.1223
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0119 0.0218
Schistosoma mansoni coup transcription factor 0.0046 0.0148 0.0287
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.005 0.0172 0.0402
Echinococcus granulosus alpha 1A adrenergic receptor 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0286 0.1564 0.2997
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0029 0.0047
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 0.016 0.0311
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0024 0.0021 0.0031
Echinococcus granulosus neuropeptides capa receptor 0.0048 0.016 0.0311
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0093 0.0424 0.1034
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0247 0.0523
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0181 0.0374
Trypanosoma brucei C-8 sterol isomerase, putative 0.0775 0.4447 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0024 0.0021 0.0015
Echinococcus granulosus serotonin transporter 0.047 0.265 0.5317
Leishmania major hypothetical protein, conserved 0.0036 0.0091 0.017
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0046 0.0148 0.0287
Mycobacterium ulcerans hypothetical protein 0.0027 0.0039 0.0062
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.0647 0.1605
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0775 0.4447 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0259 0.0488
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.016 0.0311
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.033 0.1828 0.3503
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0035 0.0082 0.0154
Loa Loa (eye worm) MBCTL1 0.0066 0.0265 0.0499
Loa Loa (eye worm) serotonin transporter b 0.047 0.265 0.5084
Brugia malayi Serotonin receptor 0.0048 0.016 0.0298
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Brugia malayi MH2 domain containing protein 0.0026 0.0029 0.0045
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0112 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.016 0.0311
Onchocerca volvulus 0.0058 0.0218 0.0702
Toxoplasma gondii exonuclease III APE 0.0037 0.0096 0.155
Brugia malayi PHD-finger family protein 0.0034 0.0081 0.0145
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0119 0.0228
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0091 0.0011
Brugia malayi hypothetical protein 0.0036 0.0089 0.0161
Echinococcus multilocularis neuropeptide Y receptor 0.0048 0.016 0.0155
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0048 0.016 0.0298
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.0218 0.0213
Brugia malayi Carboxylesterase family protein 0.0082 0.0361 0.0684
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0029 0.0023
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0046 0.0148 0.0143
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.0349 0.069
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0119 0.0228
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0335 0.0662
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0096 0.0322
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0093 0.0424 0.1034
Echinococcus granulosus acetylcholinesterase 0.0082 0.0361 0.0715
Loa Loa (eye worm) hypothetical protein 0.008 0.0349 0.066
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Onchocerca volvulus Peroxidasin homolog 0.0032 0.0066 0.0198
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0119 0.0583 0.0578
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.016 0.0155
Echinococcus granulosus allatostatin A receptor 0.0048 0.016 0.0311
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0039 0.0067
Echinococcus multilocularis neuropeptide FF receptor 2 0.0048 0.016 0.0155
Trichomonas vaginalis DNA polymerase eta, putative 0.0073 0.0308 0.0764
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0046 0.0148 0.0274
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0181 0.0374
Onchocerca volvulus 0.0048 0.016 0.0511
Mycobacterium ulcerans beta-lactamase 0.0036 0.0091 0.0193
Echinococcus multilocularis fmrfamide receptor 0.0048 0.016 0.0155
Schistosoma mansoni blooms syndrome DNA helicase 0.0032 0.0068 0.0124
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0349 0.0752
Echinococcus multilocularis muscleblind protein 0.0149 0.0759 0.0754
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0091 0.0176
Brugia malayi Animal haem peroxidase family protein 0.0032 0.0066 0.0115
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.012 0.0589 0.1457
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0157 0.1224
Mycobacterium leprae Probable lipase LipE 0.0036 0.0091 0.0176
Brugia malayi putative neuropeptide receptor 0.0048 0.016 0.0298
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.033 0.1828 0.3663
Schistosoma mansoni sodium/chloride dependent transporter 0.047 0.265 0.5317
Schistosoma mansoni biogenic amine receptor 0.0048 0.016 0.0311
Brugia malayi Steroid receptor seven-up type 2 0.0046 0.0148 0.0274
Loa Loa (eye worm) hypothetical protein 0.0082 0.0361 0.0684
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.0653 0.1244
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0152 0.0775 0.1547
Echinococcus granulosus 7tm_1 domain containing protein 0.0048 0.016 0.0311
Leishmania major C-8 sterol isomerase-like protein 0.0775 0.4447 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0096 0.003
Schistosoma mansoni lamin 0.0033 0.007 0.013
Loa Loa (eye worm) animal heme peroxidase 0.0032 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.047 0.265 0.5084
Onchocerca volvulus 0.0066 0.0269 0.087
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0091 0.0176
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0286 0.1564 0.1559
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0091 0.0176
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0166 0.034
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0048 0.016 0.0155
Echinococcus multilocularis dna polymerase kappa 0.0073 0.0308 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0046 0.0148 0.0274
Echinococcus granulosus g protein coupled receptor 0.0048 0.016 0.0311
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0096 0.1554
Echinococcus multilocularis ecdysone induced protein 78C 0.0046 0.0148 0.0143
Schistosoma mansoni tar DNA-binding protein 0.0281 0.1534 0.3073
Schistosoma mansoni neuropeptide F-like receptor 0.0048 0.016 0.0311
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.0589 0.1471
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.0653 0.162
Mycobacterium tuberculosis Conserved protein 0.0036 0.0091 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0046 0.0148 0.0274
Echinococcus granulosus lamin dm0 0.0033 0.007 0.013
Echinococcus multilocularis peroxidasin 0.0032 0.0066 0.006
Schistosoma mansoni hypothetical protein 0.004 0.0112 0.0214
Loa Loa (eye worm) hypothetical protein 0.0033 0.007 0.0124
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.016 0.0155
Brugia malayi RE15519p 0.0048 0.016 0.0298
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0046 0.0148 0.0274
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Onchocerca volvulus 0.0048 0.016 0.0511
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.016 0.0311
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.1011 0.2542
Loa Loa (eye worm) acetylcholinesterase 1 0.0082 0.0361 0.0684
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0775 0.4447 0.854
Trichomonas vaginalis esterase, putative 0.0036 0.0091 0.0011
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0046 0.0148 0.0287
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0157 0.296
Schistosoma mansoni peroxidasin 0.0032 0.0066 0.012
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0044 0.0065
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.033 0.1828 0.3663
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.047 0.265 0.5084
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.0653 0.162
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 0.016 0.0155
Echinococcus multilocularis neuropeptide receptor 0.0048 0.016 0.0155
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0125 0.0618 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0046 0.0148 0.0287
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.0653 0.1301
Brugia malayi ORL1-like opioid receptor 0.0048 0.016 0.0298
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0148 0.0143
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.016 0.0155
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0047 0.0153 0.2865
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.016 0.0155
Brugia malayi 6-phosphofructokinase 0.0131 0.0653 0.1244
Schistosoma mansoni lozenge 0.0067 0.0274 0.054
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.203 0.4545
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0033 0.0073 0.013
Echinococcus granulosus somatostatin receptor 0.0048 0.016 0.0311
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0079 0.0345 0.0847
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.033 0.1828 0.1823
Brugia malayi Bromodomain containing protein 0.0095 0.0438 0.0831
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0039 0.0067
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni myosin xvIII 0.0048 0.016 0.0311
Brugia malayi mbt repeat family protein 0.0058 0.0218 0.0408
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0111 0.0535 0.1332
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.033 0.1828 0.3503
Mycobacterium ulcerans hypothetical protein 0.0125 0.0618 0.1547
Onchocerca volvulus 0.0048 0.016 0.0511
Echinococcus granulosus sex peptide receptor 0.0048 0.016 0.0311
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0046 0.0148 0.0274
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0073 0.0132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0046 0.0148 0.0274
Loa Loa (eye worm) hypothetical protein 0.0024 0.0021 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0281 0.1534 0.3073
Loa Loa (eye worm) hypothetical protein 0.0093 0.0424 0.0805
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0046 0.0148 0.0287
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0684 0.3914 1
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.0653 0.1438
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0057 0.0213 0.049
Echinococcus granulosus neuropeptide FF receptor 2 0.0048 0.016 0.0311
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0042 0.0124 0.0126
Mycobacterium tuberculosis Conserved hypothetical protein 0.0125 0.0618 0.1532
Plasmodium falciparum thioredoxin reductase 0.0057 0.0215 0.4499
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Onchocerca volvulus 0.047 0.265 0.8734
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0054 0.0199 0.3215
Loa Loa (eye worm) hypothetical protein 0.0046 0.0148 0.0274
Loa Loa (eye worm) hypothetical protein 0.0149 0.0759 0.1448
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0112 0.0204
Mycobacterium tuberculosis Conserved hypothetical protein 0.0125 0.0618 0.1532
Brugia malayi RNA recognition motif domain containing protein 0.0281 0.1534 0.2939
Loa Loa (eye worm) hypothetical protein 0.0035 0.0082 0.0147
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.016 0.0155
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.016 0.0311
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0029 0.0023
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0088 0.029
Brugia malayi Peroxidasin 0.0032 0.0066 0.0115
Treponema pallidum hypothetical protein 0.0027 0.0039 0.0108
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0042 0.0124 0.0238
Onchocerca volvulus Peroxidase homolog 0.0032 0.0066 0.0198
Schistosoma mansoni growth hormone secretagogue receptor 0.0048 0.016 0.0311
Echinococcus granulosus FTZ F1 alpha 0.0046 0.0148 0.0287
Loa Loa (eye worm) translation initiation factor 4E 0.0042 0.0124 0.0227
Echinococcus granulosus serotonin receptor 0.0048 0.016 0.0311
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0076 0.0329 0.065
Echinococcus multilocularis zinc finger protein 0.0028 0.0043 0.0037
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0096 0.0182
Echinococcus granulosus histone acetyltransferase KAT2B 0.0054 0.0199 0.0388
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0115
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.203 0.4545
Brugia malayi Animal haem peroxidase family protein 0.0032 0.0066 0.0115
Leishmania major DNA polymerase eta, putative 0.0043 0.0134 0.0269
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0048 0.016 0.0155
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0046 0.0148 0.0287
Loa Loa (eye worm) bromodomain containing protein 0.0026 0.0029 0.0046
Trichomonas vaginalis glutaminase, putative 0.0317 0.1747 0.5742
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0057 0.0213 0.0507
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.047 0.265 0.5317
Schistosoma mansoni tar DNA-binding protein 0.0281 0.1534 0.3073
Schistosoma mansoni biogenic amine (5HT) receptor 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0074
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0038 0.0104 0.0201
Loa Loa (eye worm) latrophilin receptor protein 2 0.0286 0.1564 0.2997
Echinococcus multilocularis orexin receptor type 2 0.0048 0.016 0.0155
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0218 0.0427
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.016 0.0311
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0024 0.0022 0.0031
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0048 0.016 0.0311
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0053 0.0236
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0299 0.1641 0.3145
Loa Loa (eye worm) hypothetical protein 0.0046 0.0148 0.0274
Echinococcus multilocularis dna polymerase eta 0.0072 0.03 0.0295
Loa Loa (eye worm) G-protein coupled receptor 0.0048 0.016 0.0298
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0125 0.0618 0.1547
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0088 0.0629
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0088 0.1415
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.0653 0.1438
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0215 0.0451
Schistosoma mansoni tar DNA-binding protein 0.0281 0.1534 0.3073
Echinococcus granulosus zinc finger protein 0.0028 0.0043 0.0075
Brugia malayi Animal haem peroxidase family protein 0.0032 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0096 0.0182
Echinococcus multilocularis neuropeptide Y receptor 0.0048 0.016 0.0155
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.012 0.0589 0.0584
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.0349 0.5641
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0112 0.0204
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0046 0.0148 0.0274
Onchocerca volvulus 0.0048 0.016 0.0511
Toxoplasma gondii endonuclease IV APN 0.0093 0.0424 0.6861
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Onchocerca volvulus Dual oxidase homolog 0.0032 0.0066 0.0198
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0298
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0054 0.0199 0.0385
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0096 0.0182
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.0349 0.069
Echinococcus multilocularis g protein coupled receptor 0.0048 0.016 0.0155
Brugia malayi hypothetical protein 0.0048 0.016 0.0298
Onchocerca volvulus Peroxidase homolog 0.0032 0.0066 0.0198
Schistosoma mansoni amine GPCR 0.0048 0.016 0.0311
Mycobacterium ulcerans hypothetical protein 0.0125 0.0618 0.1547
Loa Loa (eye worm) hypothetical protein 0.0903 0.5207 1
Schistosoma mansoni amine GPCR 0.0048 0.016 0.0311
Onchocerca volvulus 0.0048 0.016 0.0511
Echinococcus granulosus lamin 0.0033 0.007 0.013
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.0732 0.1825
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0265 0.026
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0152 0.0775 0.077
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.016 0.0311
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0035 0.0082 0.0147
Plasmodium vivax ubiquitin activating enzyme, putative 0.0058 0.0222 0.4671
Brugia malayi beta-lactamase family protein 0.0036 0.0091 0.0163

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) < 5 % Inhibition of human AchE-induced amyloid beta aggregation at 100 uM ChEMBL. 18181565
Activity (ADMET) = 13.3 % Viability of rotifers against doxorubicin toxicity at 10 uM ChEMBL. 16640342
Activity (ADMET) = 14.1 % Viability of rotifers against hydrogen peroxide toxicity at 10 uM ChEMBL. 16640342
Activity (functional) = 58.5 % Percentage increase of intracellular reactive oxygen species in neuronal cells at 50 uM ChEMBL. 15658850
Activity (functional) = 74.33 % Percentage increase of intracellular reactive oxygen species in neuronal cells at 10 uM ChEMBL. 15658850
Activity (functional) = 79.5 % Percentage increase of intracellular reactive oxygen species in neuronal cells at 5 uM ChEMBL. 15658850
Activity (functional) = 83 % Percentage increase of intracellular reactive oxygen species in neuronal cells at 1 uM ChEMBL. 15658850
Activity (functional) = 86 % Percentage increase of intracellular reactive oxygen species in neuronal cells at 0 uM ChEMBL. 15658850
Activity (functional) = 90.25 % Percentage increase of intracellular reactive oxygen species in neuronal cells at 0.5 uM ChEMBL. 15658850
Activity (functional) = 91.25 % Percentage increase of intracellular reactive oxygen species in neuronal cells at 0.1 uM ChEMBL. 15658850
Activity (functional) = -18.6 nM Hydroxyl radical scavenging activity by ABTS competition assay per 30 mins at 1 umol/mL ChEMBL. 16640342
Activity (functional) = 44.1 nM Radical reducing potency by ABTS cation radical reduction assay per 30 mins at 1 umol/mL ChEMBL. 16640342
EC50 (functional) = 121.6 uM Ability of the compound for prevention of GSH depletion was measured in mouse ChEMBL. 12031315
GI50 (functional) -5 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.523 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.465 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.366 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (binding) = 1 nM Inhibition of human AchE ChEMBL. 18181565
IC50 (binding) > 1000000 nM Inhibitory concentration against human recombinant acetylcholinesterase ChEMBL. 15658850
IC50 (binding) > 1000000 nM Inhibitory concentration against human recombinant butyrylcholinesterase ChEMBL. 15658850
IC50 (binding) 0 uM In vitro inhibition concentration of the compound was evaluated on the effect of conversion by Nitric Oxide synthase of [3H]-L-arginine into [3H]-L-citrulline; Not active up to 100 microM ChEMBL. 12031315
IC50 (functional) 0 uM Antiproliferative activity was determined by colorimetric MTS assay in LNCaP cells after 72 h of incubation with compounds (1-100 uM); Not active at 100 uM ChEMBL. 15633998
IC50 (functional) = 0.62 uM PUBCHEM_BIOASSAY: AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2006, AID2011, AID2069, AID2614, AID2658] ChEMBL. No reference
IC50 (functional) = 2.4 uM Hypochlorous acid scavenging activity assessed as inhibition of DHR oxidation ChEMBL. 17624791
IC50 (binding) = 3.91 um PUBCHEM_BIOASSAY: Inhibitors of Mycobacterial Glucosamine-1-phosphate acetyl transferase (GlmU). Secondary screen. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (binding) = 4.74 uM PUBCHEM_BIOASSAY: uHTS HTRF assay for identification of inhibitors of SUMOylation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2011, AID2018, AID2069, AID2614, AID2658] ChEMBL. No reference
IC50 (functional) 5.891 uM PubChem BioAssay. An HIV-1 Tat-TAR Fluorescence Polarization (FP) Counter Screen to evaluate Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) 16.56 uM PUBCHEM_BIOASSAY: Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID782] ChEMBL. No reference
IC50 (functional) = 19.6 uM Neuroprotective effect was measured by its ability to protect mouse hippocampal neuronal HT-22 cell lines from oxidative stress caused by glutamate ChEMBL. 12031315
IC50 (functional) = 54.86 uM Antioxidant activity against formation of ROS was determined in t-BuOOH treated LNCaP cells after 24 h of incubation with compounds (1-100 uM) ChEMBL. 15633998
Inhibition (functional) = 13.1 % Inhibition of peroxynitrite-induced death of mixed cortical cells of E15 Sprague-Dawley rat embryo at 10 uM ChEMBL. 16640342
Inhibition (functional) = 14.8 % Inhibition of doxorubicin-induced death of mixed cortical cells of E15 Sprague-Dawley rat embryo at 10 uM ChEMBL. 16640342
Inhibition (functional) = 15.1 % Inhibition of hydrogen peroxide-induced death of mixed cortical cells of E15 Sprague-Dawley rat embryo at 10 uM ChEMBL. 16640342
Log Ki (binding) 0 Equilibrium dissociation constant was evaluated by radio-receptor binding assays using [3H]-prazosin to label cloned human alpha 1a expressed in CHO cells; Not tested ChEMBL. 15633998
Log Ki (binding) 0 Equilibrium dissociation constant was evaluated by radio-receptor binding assays using [3H]-prazosin to label cloned human alpha 1b expressed in CHO cells; Not tested ChEMBL. 15633998
Log Ki (binding) 0 Equilibrium dissociation constant was evaluated by radio-receptor binding assays using [3H]-prazosin to label cloned human alpha 1d expressed in CHO cells; Not tested ChEMBL. 15633998
Log Ki = 1.61 Lipophilicity, log k'w of the compound ChEMBL. 16640342
pA2 (functional) < 5 Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoreceptor) ChEMBL. 15633998
pA2 (functional) < 5 Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoreceptor) ChEMBL. 15633998
pA2 (functional) < 5 Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat thoracic aorta (alpha1D adrenoreceptor) ChEMBL. 15633998
Potency (functional) 0.0141 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.0631 uM PUBCHEM_BIOASSAY: Confirmation Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485290, AID485312, AID504464, AID504474] ChEMBL. No reference
Potency (functional) 0.1636 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 0.3444 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 0.3981 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.4775 uM PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768, AID492961] ChEMBL. No reference
Potency (functional) = 0.5012 um PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) [Related pubchem assays: 1705 (qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) ), 2324 (Probe Development Summary of Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1707 (Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay), 2517 (qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1708 (Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV)] ChEMBL. No reference
Potency (functional) 0.7079 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.8913 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (binding) 1 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) = 1.122 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.7783 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 1.9953 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] ChEMBL. No reference
Potency (binding) 2.8184 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 6.7016 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 7.0795 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 594 (Rhodamine region spectral profiling screen), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 21.5864 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 24.0151 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 27.5121 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 29.847 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 32.6427 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 37.578 uM PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 48.5577 uM PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 48.9243 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 66.8242 uM PubChem BioAssay. qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 68.5199 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 70.7946 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 79.4328 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

32 literature references were collected for this gene.

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