Detailed information for compound 48029

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 283.368 | Formula: C17H21N3O
  • H donors: 1 H acceptors: 2 LogP: 2.66 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CC(=O)Nc1c2CCCCc2nc2c1cccc2)C
  • InChi: 1S/C17H21N3O/c1-20(2)11-16(21)19-17-12-7-3-5-9-14(12)18-15-10-6-4-8-13(15)17/h3,5,7,9H,4,6,8,10-11H2,1-2H3,(H,18,19,21)
  • InChiKey: MTVWIDKCGKWCDU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0015 0.0051 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0047
Echinococcus granulosus Nuclear hormone receptor HR96 0.0217 0.3024 0.3141
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0191 0.1753
Brugia malayi laminin-like protein K08C7.3 precursor 0.005 0.0562 0.0565
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0266 0.0276
Mycobacterium ulcerans putative regulatory protein 0.007 0.0861 0.1242
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.01 0.4497
Onchocerca volvulus 0.0095 0.1226 0.1486
Echinococcus granulosus Tubulin alpha 1 chain 0.0017 0.0087 0.009
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0043 0.0458 0.0889
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0043 0.0458 0.0889
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.015 0.0156
Trichomonas vaginalis Ferredoxin 3 0.0022 0.016 0.0151
Schistosoma mansoni ap endonuclease 0.0018 0.01 0.0104
Onchocerca volvulus 0.0018 0.0104 0.0083
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.015 0.0186
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0194 0.0202
Echinococcus multilocularis tubulin alpha 1C chain 0.0017 0.0087 0.009
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.015 0.0151
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0431 0.0536
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0015 0.0051 0.0053
Onchocerca volvulus 0.0027 0.0229 0.024
Plasmodium falciparum transporter, putative 0.0095 0.1226 1
Echinococcus granulosus cytochrome P450 2K1 0.0043 0.0458 0.0476
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus multilocularis thyroid hormone receptor alpha 0.0582 0.8383 0.8708
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0022 0.016 0.0161
Brugia malayi Cytochrome P450 family protein 0.0158 0.2158 0.2172
Echinococcus multilocularis transfer RNA-Lys 0.007 0.0861 0.0894
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0022 0.016 0.0161
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0234 0.3266 0.4933
Brugia malayi Sulfatase family protein 0.0025 0.0205 0.0207
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.1528 0.1901
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0043 0.0458 0.0889
Brugia malayi Nuclear hormone receptor family member nhr-1 0.046 0.6596 0.6638
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.015 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-19 0.046 0.6596 0.6638
Onchocerca volvulus 0.0022 0.015 0.0141
Brugia malayi Doublecortin family protein 0.0041 0.0431 0.0433
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.046 0.6596 0.6852
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.189 0.1964
Loa Loa (eye worm) nuclear hormone receptor 0.0217 0.3024 0.3762
Loa Loa (eye worm) sulfotransferase domain-containing protein 0.0021 0.0137 0.0171
Schistosoma mansoni lamin 0.0052 0.0603 0.0626
Echinococcus granulosus tar DNA binding protein 0.013 0.1737 0.1804
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus multilocularis bifunctional heparan sulfate 0.0021 0.0137 0.0143
Mycobacterium leprae putative cytochrome p450 0.0043 0.0458 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0051 0.0053
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0518 0.0521
Echinococcus granulosus tubulin alpha 3 chain 0.0017 0.0087 0.009
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0051 0.0053
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.015 0.0186
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0043 0.0458 0.5098
Echinococcus multilocularis g protein coupled receptor 0.0022 0.015 0.0156
Brugia malayi nuclear receptor RXR 0.0217 0.3024 0.3043
Brugia malayi conserved hypotetical protein 0.0217 0.3024 0.3043
Treponema pallidum hypothetical protein 0.0113 0.1486 0.1746
Schistosoma mansoni sugar transporter 0.0015 0.0051 0.0053
Onchocerca volvulus 0.0022 0.015 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Loa Loa (eye worm) hypothetical protein 0.0013 0.0027 0.0034
Brugia malayi hypothetical protein 0.0317 0.4489 0.4518
Schistosoma mansoni laminin gamma-3 chain 0.005 0.0562 0.0584
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Schistosoma mansoni steroid hormone receptor ad4bp 0.046 0.6596 0.6852
Echinococcus granulosus bifunctional heparan sulfate 0.0021 0.0137 0.0143
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.01 0.0614
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0029 0.0266 0.0331
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0043 0.0458 0.0624
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Mycobacterium tuberculosis Probable oxidoreductase 0.0022 0.016 0.0238
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.015 0.0156
Brugia malayi Sulfotransferase domain containing protein 0.0021 0.0137 0.0138
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.015 0.0186
Schistosoma mansoni zinc finger protein 0.0217 0.3024 0.3141
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Onchocerca volvulus 0.0022 0.015 0.0141
Echinococcus multilocularis tubulin alpha 3 chain 0.0017 0.0087 0.009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.015 0.0156
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Brugia malayi Sugar transporter family protein 0.0015 0.0051 0.0052
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Onchocerca volvulus 0.0015 0.0051 0.0017
Schistosoma mansoni biogenic amine receptor 0.0022 0.015 0.0156
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0229 0.0238
Schistosoma mansoni cpg binding protein 0.0029 0.0264 0.0274
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0043 0.0458 0.0624
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.1226 1
Brugia malayi hypothetical protein 0.0041 0.0431 0.0433
Leishmania major ferredoxin, 2fe-2s-like protein 0.0022 0.016 0.1366
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0043 0.0458 0.0889
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.015 0.0156
Loa Loa (eye worm) agrin synaptic family protein 0.0018 0.0104 0.0129
Echinococcus multilocularis neuropeptide receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Loa Loa (eye worm) tubulin alpha chain 0.0017 0.0087 0.0108
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Brugia malayi Cytochrome P450 family protein 0.0069 0.0849 0.0854
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Loa Loa (eye worm) sulfotransferase domain-containing protein 0.0021 0.0137 0.0171
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0022 0.016 0.0167
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Brugia malayi Tubulin alpha-2 chain 0.0017 0.0087 0.0087
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.015 0.0156
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.015 0.0156
Brugia malayi hypothetical protein 0.0688 0.9936 1
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0022 0.016 0.0167
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Loa Loa (eye worm) tubulin alpha-3 chain 0.0012 0.001 0.0012
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0043 0.0458 0.5098
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Onchocerca volvulus 0.0015 0.0051 0.0017
Echinococcus granulosus intermediate filament protein 0.0052 0.0603 0.0626
Loa Loa (eye worm) sulfotransferase domain-containing protein 0.0021 0.0137 0.0171
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0205 0.2847 0.429
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0078 0.0982 0.1221
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-14 0.046 0.6596 0.6638
Schistosoma mansoni alpha tubulin 0.0017 0.0087 0.009
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0025 0.0205 0.0196
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Toxoplasma gondii sugar transporter ST2 0.0015 0.0051 0.0131
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0431 0.0447
Mycobacterium ulcerans hydrolase 0.0025 0.0205 0.0236
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.046 0.6596 0.6852
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0194 0.0185
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0095 0.1226 0.1274
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0043 0.0458 0.0624
Onchocerca volvulus 0.0021 0.0137 0.0125
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.01 0.1456
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0104 0.0104
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Brugia malayi TAR-binding protein 0.013 0.1737 0.1748
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.5638 0.5857
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0194 0.179
Loa Loa (eye worm) tubulin alpha 2 0.0013 0.0027 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.046 0.6596 0.6638
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.015 0.0141
Echinococcus multilocularis fmrfamide receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0559 0.8038 1
Mycobacterium tuberculosis Glycolipid sulfotransferase 0.0021 0.0137 0.0188
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.01 0.0614
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.046 0.6596 0.6852
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Brugia malayi RNA binding protein 0.013 0.1737 0.1748
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Schistosoma mansoni hypothetical protein 0.0047 0.0518 0.0538
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.9626 1
Loa Loa (eye worm) norepinephrine transporter 0.0559 0.8038 1
Schistosoma mansoni hypothetical protein 0.0022 0.015 0.0156
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0043 0.0458 0.0624
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0043 0.0458 0.0889
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.015 0.0151
Onchocerca volvulus 0.0041 0.0431 0.0492
Brugia malayi follicle stimulating hormone receptor 0.0244 0.3414 0.3436
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0095 0.1226 0.1274
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.016 0.1366
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.9626 1
Schistosoma mansoni survival motor neuron protein 0.0047 0.0518 0.0538
Schistosoma mansoni rab6-interacting 0.0041 0.0431 0.0447
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Onchocerca volvulus 0.0022 0.015 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Schistosoma mansoni follistatin 0.0018 0.0104 0.0108
Mycobacterium leprae Conserved hypothetical protein 0.0043 0.0458 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.1506 0.1564
Schistosoma mansoni cell polarity protein 0.005 0.0562 0.0584
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0018 0.0104 0.0129
Brugia malayi MH2 domain containing protein 0.0115 0.1528 0.1537
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0043 0.0458 0.0624
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0438 0.0455
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Mycobacterium ulcerans glycolipid sulfotransferase 0.0021 0.0137 0.0132
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus dnaJ subfamily B 0.0395 0.5638 0.5857
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.015 0.0156
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Echinococcus multilocularis tar DNA binding protein 0.013 0.1737 0.1804
Loa Loa (eye worm) tubulin alpha chain 0.0017 0.0087 0.0108
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0132 0.1774 0.2644
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0043 0.0458 0.0889
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0037 0.0039
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.015 0.0151
Leishmania major hypothetical protein, conserved 0.0024 0.0191 0.1753
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni sugar transporter 0.0015 0.0051 0.0053
Echinococcus granulosus g-protein coupled receptor 0.0022 0.015 0.0156
Echinococcus granulosus cpg binding protein 0.0029 0.0264 0.0274
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0217 0.3024 0.3141
Onchocerca volvulus 0.0027 0.0229 0.024
Echinococcus multilocularis pikachurin 0.005 0.0562 0.0584
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0234 0.3266 0.7025
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.015 0.0156
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0095 0.1226 0.1274
Brugia malayi Nuclear hormone receptor family member nhr-19 0.046 0.6596 0.6638
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.013 0.1737 0.2161
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0849 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.015 0.0156
Onchocerca volvulus 0.0022 0.015 0.0141
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0191 0.119
Echinococcus granulosus microtubule associated protein 2 0.0667 0.9626 1
Onchocerca volvulus 0.0022 0.015 0.0141
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.189 0.1902
Mycobacterium ulcerans electron transfer protein FdxB 0.0022 0.016 0.0167
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0413 0.0429
Toxoplasma gondii sugar transporter ST3 0.0015 0.0051 0.0131
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0255 0.3581 0.372
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0052 0.0603 0.075
Onchocerca volvulus 0.0022 0.015 0.0141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0559 0.058
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0229 0.2229
Onchocerca volvulus 0.0027 0.0229 0.024
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0024 0.0191 0.0237
Schistosoma mansoni hypothetical protein 0.0022 0.015 0.0156
Plasmodium vivax amine transporter, putative 0.0095 0.1226 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0648 0.0652
Mycobacterium ulcerans sulfatase 0.0025 0.0205 0.0236
Giardia lamblia Hypothetical protein 0.0025 0.0205 0.4574
Echinococcus multilocularis serotonin receptor 0.0022 0.015 0.0156
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Brugia malayi Melatonin receptor type 1A 0.0022 0.015 0.0151
Schistosoma mansoni nuclear receptor 0.0217 0.3024 0.3141
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0559 0.8038 0.8089
Brugia malayi hypothetical protein 0.0015 0.0051 0.0052
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.015 0.0156
Brugia malayi Nuclear hormone receptor E75 0.0217 0.3024 0.3043
Leishmania major hypothetical protein, conserved 0.0022 0.016 0.1366
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.01 0.0101
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0438 0.3382
Echinococcus multilocularis jun protein 0.0255 0.3581 0.372
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.015 0.0151
Echinococcus multilocularis neuropeptide receptor A26 0.0022 0.015 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0043 0.0458 0.5098
Brugia malayi Nuclear hormone receptor-like 1 0.0243 0.3406 0.3428
Echinococcus multilocularis tubulin alpha 1C chain 0.0017 0.0087 0.009
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0043 0.0458 0.0624
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.015 0.0156
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0229 0.0231
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Brugia malayi PAS domain containing protein 0.0094 0.1221 0.1229
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0246 0.0247
Mycobacterium ulcerans arylsulfatase AtsD 0.0025 0.0205 0.0236
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0217 0.3024 0.3733
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.3189 0.3313
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Schistosoma mansoni retinoic acid receptor RXR 0.046 0.6596 0.6852
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.046 0.6596 0.6852
Echinococcus granulosus g protein coupled receptor 0.0022 0.015 0.0156
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0025 0.0205 0.021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Toxoplasma gondii alpha-tubulin I, putative 0.0017 0.0087 0.0427
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0194 0.0202
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Plasmodium vivax SET domain protein, putative 0.0029 0.0266 0.1917
Brugia malayi G-protein coupled receptor 0.0022 0.015 0.0151
Brugia malayi RE15519p 0.0022 0.015 0.0151
Echinococcus multilocularis slit 2 protein 0.005 0.0562 0.0584
Echinococcus granulosus neuropeptide s receptor 0.0022 0.015 0.0156
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.015 0.0156
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi ecdysteroid receptor 0.046 0.6596 0.6638
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0104 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0012
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus multilocularis lamin dm0 0.0052 0.0603 0.0626
Loa Loa (eye worm) hypothetical protein 0.0548 0.7881 0.9805
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0043 0.0458 0.0889
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0672 0.5341
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0229 0.0238
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0388 0.9239
Loa Loa (eye worm) hypothetical protein 0.0015 0.0054 0.0067
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.046 0.6596 0.8207
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0041 0.0431 0.0536
Schistosoma mansoni hypothetical protein 0.0041 0.0431 0.0447
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0037 0.0039
Schistosoma mansoni agrin 0.0018 0.0104 0.0108
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Echinococcus granulosus GA binding protein alpha chain 0.0078 0.0982 0.102
Onchocerca volvulus 0.0022 0.015 0.0141
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Schistosoma mansoni neuropeptide receptor 0.0022 0.015 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Schistosoma mansoni sodium/chloride dependent transporter 0.0559 0.8038 0.835
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Loa Loa (eye worm) tubulin alpha 2 0.0013 0.0027 0.0034
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0194 0.179
Brugia malayi hypothetical protein 0.0025 0.0205 0.0207
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) TAR-binding protein 0.013 0.1737 0.2161
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Schistosoma mansoni nuclear hormone receptor 0.046 0.6596 0.6852
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0413 0.0429
Echinococcus multilocularis bifunctional heparan sulfate 0.0021 0.0137 0.0143
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0438 0.0429
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni opsin-like receptor 0.0022 0.015 0.0156
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0559 0.058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus agrin 0.0018 0.0104 0.0108
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0205 0.0213
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0229 0.0238
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0043 0.0458 0.0889
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Onchocerca volvulus 0.0027 0.0229 0.024
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0244 0.3414 0.4248
Echinococcus multilocularis allatostatin A receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0104 0.0129
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0692 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0431 0.3229
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Brugia malayi Nuclear hormone receptor-like 1 0.0243 0.3406 0.3428
Brugia malayi Sugar transporter family protein 0.0015 0.0051 0.0052
Brugia malayi Ets-domain containing protein 0.0078 0.0982 0.0988
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0191 0.1288
Toxoplasma gondii facilitative glucose transporter GT1 0.0015 0.0051 0.0131
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0217 0.3024 0.3733
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0194 0.0185
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.005 0.0562 0.0565
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.01 0.0075
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Brugia malayi Fli-1 protein 0.0237 0.332 0.3341
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.015 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0104 0.0129
Brugia malayi orphan nuclear receptor NR2E1 0.0217 0.3024 0.3043
Echinococcus multilocularis peroxisome assembly protein 26 0.0017 0.0087 0.009
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0073 0.0075
Loa Loa (eye worm) abnormal epIthelia family member 0.005 0.0562 0.0699
Brugia malayi Nuclear hormone receptor family member nhr-41 0.046 0.6596 0.6638
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0559 0.8038 0.835
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0051 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0043 0.0458 0.0889
Mycobacterium ulcerans arylsulfatase AtsB 0.0025 0.0205 0.0236
Onchocerca volvulus 0.0022 0.015 0.0141
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0388 0.2865
Brugia malayi Steroid receptor seven-up type 2 0.046 0.6596 0.6638
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0559 0.058
Brugia malayi hypothetical protein 0.0228 0.3189 0.3209
Brugia malayi tailless protein 0.0217 0.3024 0.3043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Trichomonas vaginalis tubulin epsilon chain, putative 0.0017 0.0087 0.0077
Echinococcus granulosus thyroid hormone receptor alpha 0.0217 0.3024 0.3141
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0043 0.0458 0.0889
Loa Loa (eye worm) sugar transporter 0.0015 0.0051 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0559 0.8038 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0217 0.3024 0.3141
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.015 0.0156
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.015 0.0156
Echinococcus granulosus bloom syndrome protein 0.0021 0.0136 0.0142
Echinococcus granulosus serotonin transporter 0.0559 0.8038 0.835
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Echinococcus multilocularis tubulin subunit TubB 0.0017 0.0087 0.009
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0043 0.0458 0.0624
Schistosoma mansoni sugar transporter 0.0015 0.0051 0.0053
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0217 0.3024 0.3141
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0132 0.1774 0.3766
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0194 0.0241
Echinococcus granulosus alpha tubulin 0.0017 0.0087 0.009
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Schistosoma mansoni hypothetical protein 0.0022 0.015 0.0156
Echinococcus multilocularis GA binding protein alpha chain 0.0078 0.0982 0.102
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Schistosoma mansoni heparan sulfate n-deacetylase/n-sulfotransferase 0.0021 0.0137 0.0143
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0043 0.0458 0.0889
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Entamoeba histolytica hypothetical protein 0.0039 0.0413 1
Plasmodium vivax ferredoxin, putative 0.0022 0.016 0.1028
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Brugia malayi hypothetical protein 0.0243 0.3406 0.3428
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.015 0.0156
Toxoplasma gondii sugar transporter ST1 0.0015 0.0051 0.0131
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0054 0.0056
Schistosoma mansoni netrin receptor unc5 0.0014 0.0037 0.0039
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.1226 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Schistosoma mansoni glucose transport protein 0.0015 0.0051 0.0053
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.015 0.0186
Trichomonas vaginalis Ferredoxin 1 0.0022 0.016 0.0151
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.015 0.0156
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0051 0.0042
Brugia malayi Cytochrome P450 family protein 0.0043 0.0458 0.0461
Schistosoma mansoni hypothetical protein 0.0014 0.0037 0.0039
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0194 0.0185
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0055 0.0648 0.1303
Echinococcus multilocularis neuropeptide receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Schistosoma mansoni RAR-like nuclear receptor 0.046 0.6596 0.6852
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.015 0.0156
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0648 0.0673
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0043 0.0458 0.0624
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Schistosoma mansoni organic anion transporter 0.0027 0.0229 0.0238
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0043 0.0458 0.0624
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0025 0.0194 0.179
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0559 0.0562
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0191 0.1753
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0849 0.1056
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0205 0.0213
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0458 0.5098
Schistosoma mansoni neuropeptide receptor 0.0022 0.015 0.0156
Schistosoma mansoni hypothetical protein 0.0122 0.162 0.1683
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0266 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.016 0.1366
Brugia malayi Nuclear hormone receptor family member nhr-25 0.046 0.6596 0.6638
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.057
Brugia malayi Protein kinase domain containing protein 0.0014 0.0037 0.0038
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Schistosoma mansoni ap endonuclease 0.0018 0.01 0.0104
Echinococcus granulosus ecdysone induced protein 78C 0.046 0.6596 0.6852
Onchocerca volvulus 0.0052 0.0603 0.0707
Onchocerca volvulus 0.0015 0.0051 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Plasmodium vivax hexose transporter 0.0015 0.0051 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Onchocerca volvulus 0.0015 0.0051 0.0017
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0194 0.0185
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.015 0.0156
Echinococcus granulosus neuropeptide receptor A26 0.0022 0.015 0.0156
Trichomonas vaginalis set domain proteins, putative 0.0229 0.3204 0.3197
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0194 0.0202
Schistosoma mansoni nuclear hormone receptor 0.0217 0.3024 0.3141
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.057
Echinococcus granulosus Ankyrin 0.0014 0.0039 0.0041
Echinococcus multilocularis ecdysone induced protein 78C 0.046 0.6596 0.6852
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.046 0.6596 0.8207
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.015 0.0186
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0136 0.0142
Brugia malayi hypothetical protein 0.0217 0.3024 0.3043
Loa Loa (eye worm) serotonin transporter b 0.0559 0.8038 1
Onchocerca volvulus 0.007 0.0861 0.1029
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0025 0.0205 0.0336
Echinococcus multilocularis FTZ F1 alpha 0.046 0.6596 0.6852
Mycobacterium tuberculosis Probable sulfatase 0.0025 0.0205 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Schistosoma mansoni organic anion transporter 0.0027 0.0229 0.0238
Echinococcus granulosus hypothetical protein 0.0022 0.015 0.0156
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.015 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0017 0.0087 0.0108
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0132 0.1774 0.2644
Entamoeba histolytica hypothetical protein 0.0039 0.0413 1
Toxoplasma gondii alpha tubulin TUBA1 0.0017 0.0087 0.0427
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Schistosoma mansoni polycystin 1-related 0.0041 0.0431 0.0447
Trypanosoma brucei alpha tubulin 0.0017 0.0087 0.0443
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Onchocerca volvulus 0.0022 0.015 0.0141
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0266 0.0276
Onchocerca volvulus 0.0095 0.1226 0.1486
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Echinococcus multilocularis sodium and chloride dependent glycine 0.0095 0.1226 0.1274
Brugia malayi Serotonin receptor 0.0022 0.015 0.0151
Echinococcus multilocularis fmrfamide receptor 0.0022 0.015 0.0156
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1234
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.005 0.0562 0.0699
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0043 0.0458 0.0624
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0241 0.0251
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0095 0.1226 0.1234
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus nuclear receptor 2DBD gamma 0.046 0.6596 0.6852
Echinococcus granulosus solute carrier family 22 0.0015 0.0051 0.0053
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0037 0.0047
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi prostaglandin transporter 0.0027 0.0229 0.0231
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.01 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0194 0.0185
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0559 0.058
Onchocerca volvulus 0.0022 0.015 0.0141
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.015 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0458 0.6568 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.189 0.1964
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.046 0.6596 0.8207
Echinococcus granulosus lamin dm0 0.0052 0.0603 0.0626
Onchocerca volvulus 0.0015 0.0051 0.0017
Brugia malayi nuclear receptor RXR 0.0243 0.3406 0.3428
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0054 0.0004
Loa Loa (eye worm) tubulin alpha-2 chain 0.0017 0.0087 0.0108
Echinococcus granulosus retinoic acid receptor rxr beta a 0.046 0.6596 0.6852
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.015 0.0156
Brugia malayi photoreceptor-specific nuclear receptor 0.046 0.6596 0.6638
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0243 0.3406 0.4238
Leishmania major protein kinase, putative 0.0025 0.0194 0.179
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0229 0.0285
Brugia malayi Pre-SET motif family protein 0.0202 0.2796 0.2814
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0022 0.016 0.0238
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Onchocerca volvulus 0.0022 0.015 0.0141
Echinococcus granulosus sodium and chloride dependent glycine 0.0095 0.1226 0.1274
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0431 0.0447
Loa Loa (eye worm) hypothetical protein 0.0024 0.0191 0.0238
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.046 0.6596 0.6852
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.016 0.1366
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0266 0.1934
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1234
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0194 0.0185
Brugia malayi nuclear receptor NHR-88 0.0217 0.3024 0.3043
Schistosoma mansoni glucose transport protein 0.0015 0.0051 0.0053
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Plasmodium falciparum ferredoxin, putative 0.0022 0.016 0.0927
Echinococcus multilocularis serotonin transporter 0.0559 0.8038 0.835
Echinococcus multilocularis musashi 0.0052 0.0603 0.0626
Brugia malayi hypoxia-induced factor 1 0.0292 0.4129 0.4155
Loa Loa (eye worm) hypothetical protein 0.0025 0.0194 0.0241
Schistosoma mansoni nuclear receptor nhr-48 0.0217 0.3024 0.3141
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0043 0.0458 0.0889
Echinococcus multilocularis expressed protein 0.0018 0.0104 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Schistosoma mansoni hypothetical protein 0.0022 0.015 0.0156
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0099 0.041
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.015 0.0156
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.015 0.0156
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.015 0.0156
Schistosoma mansoni sodium/chloride dependent transporter 0.0095 0.1226 0.1274
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0051 0.0131
Onchocerca volvulus 0.0015 0.0051 0.0017
Echinococcus granulosus follistatin 0.0018 0.0104 0.0108
Echinococcus multilocularis sex peptide receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi RNA recognition motif domain containing protein 0.013 0.1737 0.1748
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0849 0.1056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0266 0.0276
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.015 0.0156
Brugia malayi EGF-like domain containing protein 0.005 0.0562 0.0565
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.015 0.0156
Brugia malayi AKH receptor 0.0022 0.015 0.0151
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.046 0.6596 0.6638
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.046 0.6596 0.8207
Echinococcus multilocularis agrin 0.0018 0.0104 0.0108
Entamoeba histolytica hypothetical protein 0.0039 0.0413 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.015 0.0156
Echinococcus multilocularis cpg binding protein 0.0029 0.0264 0.0274
Trichomonas vaginalis Ferredoxin 2 0.0022 0.016 0.0151
Brugia malayi putative neuropeptide receptor 0.0022 0.015 0.0151
Mycobacterium tuberculosis Possible oxygenase 0.0022 0.016 0.0238
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0024 0.0191 0.0237
Brugia malayi larval opioid receptor 0.0022 0.015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni sodium-dependent amino acid transporter 0.0095 0.1226 0.1274
Onchocerca volvulus Bile acid receptor homolog 0.046 0.6596 0.8198
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus granulosus Nuclear hormone receptor HR96 0.0217 0.3024 0.3141
Onchocerca volvulus 0.0015 0.0051 0.0017
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0043 0.0458 0.0624
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0025 0.0194 0.179
Echinococcus granulosus bifunctional heparan sulfate 0.0021 0.0137 0.0143
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0229 0.024
Onchocerca volvulus 0.0022 0.015 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Brugia malayi hypothetical protein 0.0039 0.0413 0.0415
Leishmania major cytochrome p450-like protein 0.0043 0.0458 0.5098
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0055 0.0648 0.7475
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0458 0.5098
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0104 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Schistosoma mansoni glucose transport protein 0.0015 0.0051 0.0053
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.01 0.0091
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0043 0.0458 0.0889
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Echinococcus granulosus peroxisome assembly protein 26 0.0017 0.0087 0.009
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0025 0.0194 0.179
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.015 0.0156
Schistosoma mansoni alpha tubulin 0.0017 0.0087 0.009
Echinococcus granulosus nuclear receptor nhr 48 0.0217 0.3024 0.3141
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.015 0.0156
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.1506 0.1564
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0025 0.0194 0.179
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Schistosoma mansoni tubulin subunit alpha 0.0017 0.0087 0.009
Brugia malayi nuclear hormone receptor 0.0217 0.3024 0.3043
Echinococcus multilocularis g protein coupled receptor 0.0022 0.015 0.0156
Schistosoma mansoni sodium/chloride dependent transporter 0.0095 0.1226 0.1274
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0025 0.0205 0.0255
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.046 0.6596 0.8207
Echinococcus multilocularis Tubulin alpha 1 chain 0.0017 0.0087 0.009
Trypanosoma cruzi alpha tubulin, putative 0.0017 0.0087 0.0443
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0037 0.0038
Schistosoma mansoni adenoreceptor 0.0022 0.015 0.0156
Brugia malayi tubulin alpha-2 chain 0.0017 0.0087 0.0087
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.01 0.0614
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0095 0.1226 1
Brugia malayi Dopamine receptor 0.0022 0.015 0.0151
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0022 0.016 0.1366
Schistosoma mansoni thyroid hormone receptor 0.0582 0.8383 0.8708
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.015 0.0156
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.015 0.0156
Schistosoma mansoni cpg binding protein 0.0028 0.0241 0.025
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0431 0.0447
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.015 0.0156
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.005 0.0562 0.0584
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Brugia malayi ORL1-like opioid receptor 0.0022 0.015 0.0151
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0051 0.0064
Loa Loa (eye worm) hypothetical protein 0.0025 0.0205 0.0255
Loa Loa (eye worm) RecQ helicase 0.0021 0.0136 0.017
Treponema pallidum hypothetical protein 0.0093 0.1194 0.1378
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0043 0.0458 0.0889
Echinococcus multilocularis Tubulin alpha 1 chain 0.0017 0.0087 0.009
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0025 0.0205 0.0196
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0136 0.0127
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.015 0.0151
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0438 0.3368
Onchocerca volvulus 0.0022 0.016 0.0154
Schistosoma mansoni hypothetical protein 0.0015 0.0051 0.0053
Onchocerca volvulus 0.0217 0.3024 0.3733
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0194 0.0185
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.01 0.0614
Schistosoma mansoni nuclear hormone receptor 0.0217 0.3024 0.3141
Onchocerca volvulus 0.0021 0.0137 0.0125
Schistosoma mansoni single-minded 0.0094 0.1221 0.1269
Brugia malayi Tubulin alpha-2 chain 0.0017 0.0087 0.0087
Toxoplasma gondii exonuclease III APE 0.0018 0.01 0.0542
Schistosoma mansoni hypothetical protein 0.0207 0.2879 0.2991
Echinococcus granulosus neuropeptide receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) DR-78 0.0217 0.3024 0.3762
Onchocerca volvulus 0.0217 0.3024 0.3733
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Toxoplasma gondii ferodoxin FD 0.0022 0.016 0.1046
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Giardia lamblia [2Fe-2S] ferredoxin 0.0022 0.016 0.3237
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.2796 0.3478
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0326 0.4627 0.7021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0648 0.0915
Brugia malayi hypothetical protein 0.0015 0.0051 0.0052
Echinococcus granulosus tubulin subunit TubB 0.0017 0.0087 0.009
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0255 0.3581 0.372
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Leishmania major protein kinase, putative 0.0025 0.0194 0.179
Onchocerca volvulus 0.0022 0.015 0.0141
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0229 0.024
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0043 0.0458 0.0624
Schistosoma mansoni tubulin subunit alpha 0.0017 0.0087 0.009
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi ecdysone receptor 0.0217 0.3024 0.3043
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi Death domain containing protein 0.0014 0.0037 0.0038
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0095 0.1226 0.1274
Echinococcus granulosus g protein coupled receptor 0.0022 0.015 0.0156
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.015 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Brugia malayi G protein-coupled receptor 0.0022 0.015 0.0151
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0043 0.0458 0.0889
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi hypothetical protein 0.0015 0.0051 0.0052
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0027 0.0224 0.0279
Echinococcus granulosus allatostatin A receptor 0.0022 0.015 0.0156
Echinococcus multilocularis hypothetical protein 0.0017 0.0087 0.009
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0326 0.4627 0.7021
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Loa Loa (eye worm) nuclear receptor NHR-67 0.0217 0.3024 0.3762
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.01 0.0523
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0431 0.0447
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0217 0.3024 0.3141
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Trichomonas vaginalis Ferredoxin 4 0.0022 0.016 0.0151
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Brugia malayi nuclear receptor NHR-67 0.0217 0.3024 0.3043
Treponema pallidum quinoline 2-oxidoreductase 0.011 0.1448 0.1697
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0013 0.0027 0.0034
Schistosoma mansoni coup transcription factor 0.046 0.6596 0.6852
Entamoeba histolytica hypothetical protein 0.0039 0.0413 1
Schistosoma mansoni histamine h1 receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.1528 0.1901
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0194 0.0185
Schistosoma mansoni jun-related protein 0.0207 0.2879 0.2991
Brugia malayi major facilitator superfamily protein 0.0015 0.0051 0.0052
Brugia malayi nuclear hormone receptor 0.046 0.6596 0.6638
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.015 0.0156
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0229 0.0238
Schistosoma mansoni gabp alpha 0.0078 0.0982 0.102
Loa Loa (eye worm) hypothetical protein 0.0041 0.0431 0.0536
Echinococcus multilocularis somatostatin receptor 0.0022 0.015 0.0156
Plasmodium vivax tubulin alpha chain, putative 0.0017 0.0087 0.0408
Schistosoma mansoni biogenic amine receptor 0.0022 0.015 0.0156
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.015 0.0156
Echinococcus granulosus sex peptide receptor 0.0022 0.015 0.0156
Mycobacterium ulcerans arylsulfatase, AslA 0.0025 0.0205 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Brugia malayi neuropeptide F receptor 0.0022 0.015 0.0151
Loa Loa (eye worm) cytochrome P450 0.0043 0.0458 0.057
Trypanosoma brucei alpha tubulin 0.0017 0.0087 0.0443
Echinococcus granulosus Tubulin alpha 1 chain 0.0017 0.0087 0.009
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.015 0.0156
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0229 0.0231
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.015 0.0156
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0069 0.0849 0.1224
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0559 0.058
Schistosoma mansoni Tr4/Tr2 (homologue) 0.046 0.6596 0.6852
Brugia malayi CXXC zinc finger family protein 0.0028 0.0241 0.0243
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0246 0.0306
Echinococcus granulosus tubulin alpha 3 chain 0.0017 0.0087 0.009
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0043 0.0458 0.0624
Schistosoma mansoni hypothetical protein 0.0395 0.5638 0.5857
Echinococcus multilocularis neuropeptide s receptor 0.0022 0.015 0.0156
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0388 1
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0878 0.0913
Onchocerca volvulus 0.0028 0.0241 0.0254
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Onchocerca volvulus 0.0047 0.0518 0.0601
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Schistosoma mansoni loxhd1 0.0041 0.0431 0.0447
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Schistosoma mansoni rab6-interacting 0.0041 0.0431 0.0447
Loa Loa (eye worm) hypothetical protein 0.0016 0.0075 0.0093
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1234
Loa Loa (eye worm) sugar transporter 0.0015 0.0051 0.0064
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0017 0.0087 0.0077
Onchocerca volvulus 0.0015 0.0051 0.0017
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0194 0.179
Mycobacterium ulcerans glycolipid sulfotransferase 0.0021 0.0137 0.0132
Onchocerca volvulus 0.02 0.2776 0.3424
Onchocerca volvulus 0.0015 0.0051 0.0017
Brugia malayi Intermediate filament tail domain containing protein 0.0052 0.0603 0.0607
Plasmodium falciparum alpha tubulin 2 0.0017 0.0087 0.0301
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.015 0.0186
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0559 0.058
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0095 0.1226 0.1274
Echinococcus granulosus Tubulin alpha 1 chain 0.0017 0.0087 0.009
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Plasmodium vivax sugar transporter, putative 0.0015 0.0051 0.0111
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0136 0.0137
Brugia malayi major facilitator superfamily protein 0.0015 0.0051 0.0052
Trypanosoma brucei cytochrome P450, putative 0.0069 0.0849 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0217 0.3024 0.3141
Plasmodium falciparum amino acid transporter, putative 0.0095 0.1226 1
Echinococcus granulosus Adrenodoxin mitochondrial 0.0022 0.016 0.0167
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0228 0.3189 0.3968
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0266 0.0276
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Giardia lamblia Alpha-tubulin 0.0017 0.0087 0.1049
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0217 0.3024 0.3043
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.015 0.0141
Mycobacterium ulcerans electron transfer protein 0.0022 0.016 0.0167
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.046 0.6596 0.8207
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.015 0.0156
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0043 0.0458 0.0624
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Schistosoma mansoni thyroid hormone receptor 0.0582 0.8383 0.8708
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0194 0.0185
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0051 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0104 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Echinococcus multilocularis neurogenic locus notch protein 0.005 0.0562 0.0584
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.046 0.6596 0.8198
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Schistosoma mansoni biogenic amine receptor 0.0022 0.015 0.0156
Trichomonas vaginalis Ferredoxin 7 0.0022 0.016 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) alpha-tubulin 0.0017 0.0087 0.0108
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-49 0.046 0.6596 0.6638
Onchocerca volvulus Putative transporter 0.0015 0.0051 0.0017
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.015 0.0156
Onchocerca volvulus 0.0015 0.0051 0.0017
Brugia malayi bZIP transcription factor family protein 0.0255 0.3581 0.3604
Schistosoma mansoni opsin-like receptor 0.0022 0.015 0.0156
Echinococcus multilocularis serotonin receptor 0.0022 0.015 0.0156
Brugia malayi nuclear hormone receptor family member odr-7 0.0217 0.3024 0.3043
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.046 0.6596 0.6852
Schistosoma mansoni neuropeptide receptor 0.0022 0.015 0.0156
Onchocerca volvulus 0.0052 0.0603 0.0707
Brugia malayi neuropeptide F receptor 0.0022 0.015 0.0151
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0022 0.016 1
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0194 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Brugia malayi Uncoordinated protein 44 0.0014 0.0037 0.0038
Brugia malayi Dopamine receptor protein 2 0.0022 0.015 0.0151
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0095 0.1226 0.1274
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Mycobacterium ulcerans oxygenase 0.0022 0.016 0.0167
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0043 0.0458 0.0624
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0241 0.03
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi Cytochrome P450 family protein 0.0069 0.0849 0.0854
Schistosoma mansoni tubulin subunit alpha 0.0017 0.0087 0.009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus multilocularis RUN 0.0041 0.0431 0.0447
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.015 0.0186
Schistosoma mansoni alpha tubulin 0.0017 0.0087 0.009
Trypanosoma brucei electron transfer protein, putative 0.0022 0.016 0.1366
Onchocerca volvulus 0.023 0.3205 0.396
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0243 0.3406 0.3538
Brugia malayi Sugar transporter family protein 0.0015 0.0051 0.0052
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Echinococcus granulosus tubulin alpha 1C chain 0.0017 0.0087 0.009
Onchocerca volvulus 0.0015 0.0051 0.0017
Echinococcus multilocularis orexin receptor type 2 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.1226 1
Echinococcus granulosus orexin receptor type 2 0.0022 0.015 0.0156
Brugia malayi Sulfotransferase domain containing protein 0.0021 0.0137 0.0138
Trichomonas vaginalis tubulin epsilon chain, putative 0.0017 0.0087 0.0077
Echinococcus granulosus g protein coupled receptor 0.0022 0.015 0.0156
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0137 0.0171
Schistosoma mansoni cytochrome P450 0.0043 0.0458 0.0476
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.015 0.0156
Loa Loa (eye worm) hypoxia-induced factor 1 0.0292 0.4129 0.5137
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi hypothetical protein 0.0016 0.0064 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0043 0.0458 0.0889
Brugia malayi hypothetical protein 0.0027 0.0229 0.0231
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Plasmodium falciparum alpha tubulin 1 0.0017 0.0087 0.0301
Echinococcus multilocularis sodium and chloride dependent glycine 0.0095 0.1226 0.1274
Onchocerca volvulus 0.0015 0.0051 0.0017
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.015 0.0151
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.046 0.6596 0.6852
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0243 0.3406 0.3538
Echinococcus granulosus solute carrier family 22 0.0015 0.0051 0.0053
Loa Loa (eye worm) hypothetical protein 0.0067 0.0815 0.1014
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus multilocularis nuclear receptor nhr 48 0.0217 0.3024 0.3141
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Schistosoma mansoni aryl hydrocarbon receptor 0.0094 0.1221 0.1269
Trichomonas vaginalis aldehyde oxidase, putative 0.0692 1 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.046 0.6596 0.6852
Brugia malayi secreted modular calcium-binding protein 1 0.0018 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Echinococcus granulosus RUN 0.0041 0.0431 0.0447
Brugia malayi Pre-SET motif family protein 0.0029 0.0266 0.0268
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi sulfakinin receptor protein 0.0022 0.015 0.0151
Giardia lamblia Alpha-tubulin 0.0017 0.0087 0.1049
Loa Loa (eye worm) intermediate filament protein 0.0052 0.0603 0.075
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0055 0.0648 0.0673
Echinococcus multilocularis solute carrier family 22 0.0015 0.0051 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.046 0.6596 0.8207
Brugia malayi tubulin alpha chain - mouse 0.0017 0.0087 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0039 0.0041
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0217 0.3024 0.3141
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-25 0.046 0.6596 0.6638
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Schistosoma mansoni opsin-like receptor 0.0022 0.015 0.0156
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Treponema pallidum sodium- and chloride- dependent transporter 0.0559 0.8038 1
Schistosoma mansoni lipoxygenase 0.0114 0.1506 0.1564
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0431 0.3304
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Onchocerca volvulus 0.0025 0.0194 0.0196
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0037 0.0039
Brugia malayi steroid hormone receptor 0.046 0.6596 0.6638
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Loa Loa (eye worm) cytochrome P450 family protein 0.0158 0.2158 0.2685
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0243 0.3406 0.3538
Onchocerca volvulus Protein ultraspiracle homolog 0.046 0.6596 0.8198
Loa Loa (eye worm) hypothetical protein 0.0248 0.3478 0.4328
Echinococcus granulosus ferredoxin 0.0022 0.016 0.0167
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0229 0.024
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0022 0.016 0.0199
Echinococcus multilocularis Ankyrin 0.0014 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0051 0.0589 0.0732
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Toxoplasma gondii ferredoxin, putative 0.0022 0.016 0.1046
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Loa Loa (eye worm) solute carrier family 6 member 4 0.0559 0.8038 1
Schistosoma mansoni adrenodoxin 0.0022 0.016 0.0167
Brugia malayi intermediate filament protein 0.0052 0.0603 0.0607
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0266 0.0276
Brugia malayi GnHR receptor homolog 0.0022 0.015 0.0151
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0438 0.3382
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0849 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.01 0.0419
Echinococcus granulosus somatostatin receptor 0.0022 0.015 0.0156
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0217 0.3024 0.3141
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0217 0.3024 0.3141
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0191 0.119
Loa Loa (eye worm) RNA binding protein 0.013 0.1737 0.2161
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.015 0.0156
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0713 0.0741
Onchocerca volvulus 0.0027 0.0229 0.024
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.015 0.0186
Brugia malayi hypothetical protein 0.0243 0.3406 0.3428
Schistosoma mansoni nuclear receptor 0.0217 0.3024 0.3141
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0049
Onchocerca volvulus 0.0095 0.1226 0.1486
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0051 0.0053
Onchocerca volvulus 0.0022 0.015 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Leishmania major cytochrome p450-like protein 0.0043 0.0458 0.5098
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0025 0.0205 0.0336
Onchocerca volvulus 0.0559 0.8038 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Trypanosoma brucei alpha tubulin 0.0017 0.0087 0.0443
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.046 0.6596 0.6852
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.046 0.6596 0.6852
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.01 0.0417
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.015 0.0156
Mycobacterium ulcerans arylsulfatase AtsD 0.0025 0.0205 0.0236
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.016 0.1366
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0232 0.1648
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0022 0.016 0.0167
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.057
Echinococcus granulosus solute carrier family 22 0.0015 0.0051 0.0053
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Brugia malayi nuclear receptor NHR-88 0.046 0.6596 0.6638
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Schistosoma mansoni ets-related 0.0237 0.332 0.3449
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.015 0.0156
Schistosoma mansoni sugar transporter 0.0015 0.0051 0.0053
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.01 0.0104
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0431 0.0447
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0022 0.016 0.0154
Echinococcus granulosus pikachurin 0.005 0.0562 0.0584
Echinococcus granulosus jun protein 0.0255 0.3581 0.372
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0051 0.0042
Toxoplasma gondii hypothetical protein 0.0095 0.1226 1
Onchocerca volvulus 0.0015 0.0051 0.0017
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0043 0.0458 0.0624
Schistosoma mansoni cpg binding protein 0.0029 0.0264 0.0274
Echinococcus multilocularis Tubulin alpha 1 chain 0.0017 0.0087 0.009
Schistosoma mansoni myosin xvIII 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.046 0.6596 0.6852
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0194 0.0185
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0043 0.0458 0.0889
Trypanosoma brucei alpha tubulin 0.0017 0.0087 0.0443
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0043 0.0458 0.0889
Brugia malayi Nuclear hormone receptor E75 0.0217 0.3024 0.3043
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Loa Loa (eye worm) hypothetical protein 0.005 0.0562 0.0699
Onchocerca volvulus 0.0015 0.0051 0.0017
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0191 0.1305
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.015 0.0156
Brugia malayi Sulfotransferase domain containing protein 0.0021 0.0137 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-40 0.046 0.6596 0.6638
Echinococcus granulosus solute carrier family 22 0.0015 0.0051 0.0053
Mycobacterium ulcerans oxidoreductase 0.0022 0.016 0.0167
Echinococcus granulosus slit 2 protein 0.005 0.0562 0.0584
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0194 0.0202
Schistosoma mansoni hypothetical protein 0.0039 0.0413 0.0429
Brugia malayi hypothetical protein 0.0095 0.1226 0.1234
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Mycobacterium ulcerans glycolipid sulfotransferase 0.0021 0.0137 0.0132
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Mycobacterium ulcerans hypothetical protein 0.0113 0.1486 0.2202
Giardia lamblia Hypothetical protein 0.0025 0.0205 0.4574
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0051 0.0052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Plasmodium vivax hypothetical protein, conserved 0.0095 0.1226 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Echinococcus multilocularis solute carrier family 22 0.0015 0.0051 0.0053
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.015 0.0186
Onchocerca volvulus 0.0015 0.0051 0.0017
Echinococcus multilocularis solute carrier family 22 0.0015 0.0051 0.0053
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0559 0.8038 1
Trichomonas vaginalis Ferredoxin 6 0.0022 0.016 0.0151
Schistosoma mansoni lipoxygenase 0.0041 0.0431 0.0447
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.015 0.0156
Brugia malayi Serotonin receptor 0.0022 0.015 0.0151
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1525
Onchocerca volvulus 0.0022 0.015 0.0141
Echinococcus granulosus FTZ F1 alpha 0.046 0.6596 0.6852
Brugia malayi hypothetical protein 0.0024 0.0191 0.0192
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0043 0.0458 0.0889
Brugia malayi G-protein coupled receptor 0.0022 0.015 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0054 0.0056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.046 0.6596 0.6638
Echinococcus granulosus neuropeptide receptor 0.0022 0.015 0.0156
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0229 0.0231
Brugia malayi cytochrome P450 0.0043 0.0458 0.0461
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.162 0.1683
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0326 0.4627 1
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.1833 0.1904
Brugia malayi Nuclear hormone receptor family member nhr-3 0.046 0.6596 0.6638
Brugia malayi alpha-tubulin 0.0017 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Brugia malayi nuclear hormone receptor family member nhr-6 0.0217 0.3024 0.3043
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Schistosoma mansoni neuropeptide receptor 0.0022 0.015 0.0156
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0022 0.016 0.0238
Echinococcus multilocularis solute carrier family 22 0.0015 0.0051 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0043 0.0458 0.0624
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.01 0.0125
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.046 0.6596 0.6852
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.015 0.0156
Echinococcus granulosus single minded 2 0.007 0.0861 0.0894
Brugia malayi hypothetical protein 0.0217 0.3024 0.3043
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0243 0.3406 0.3538
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0217 0.3024 0.3141
Echinococcus granulosus sodium and chloride dependent glycine 0.0095 0.1226 0.1274
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1525
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0051 0.0064
Schistosoma mansoni hypothetical protein 0.0043 0.0458 0.0476
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Echinococcus multilocularis 0.0043 0.0458 0.0476
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0136 0.0127
Echinococcus granulosus neurogenic locus notch protein 0.005 0.0562 0.0584
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0266 0.0276
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Leishmania major ferredoxin 2fe-2s-like protein 0.0022 0.016 0.1366
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.015 0.0156
Brugia malayi hypothetical protein 0.02 0.2776 0.2794
Brugia malayi hypothetical protein 0.0027 0.0229 0.0231
Loa Loa (eye worm) acetyltransferase 0.014 0.189 0.2352
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.016 0.1366
Mycobacterium ulcerans oxidoreductase 0.0022 0.016 0.0167
Toxoplasma gondii cytochrome p450 superfamily protein 0.0043 0.0458 0.3546
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Echinococcus granulosus serotonin receptor 0.0022 0.015 0.0156
Brugia malayi Ets-domain containing protein 0.0078 0.0982 0.0988
Brugia malayi bHLH-PAS transcription factor 0.007 0.0861 0.0866
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0095 0.1226 0.1274
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0438 0.0429
Onchocerca volvulus 0.0022 0.015 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus tubulin alpha 1C chain 0.0017 0.0087 0.009
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0043 0.0458 0.0624
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0191 0.1753
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Brugia malayi laminin alpha chain 0.005 0.0562 0.0565
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.3189 0.3313
Echinococcus multilocularis lamin 0.0052 0.0603 0.0626
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.057
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0051 0.0042
Onchocerca volvulus 0.0029 0.0266 0.0286
Echinococcus multilocularis follistatin 0.0018 0.0104 0.0108
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.015 0.0156
Echinococcus multilocularis tubulin alpha 3 chain 0.0017 0.0087 0.009
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Brugia malayi SPARC precursor 0.0018 0.0104 0.0104
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.015 0.0156
Onchocerca volvulus 0.046 0.6596 0.8198
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0013 0.0027 0.0018
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.01 0.0104
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0217 0.3024 0.3762
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0025 0.0205 0.0255
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0593 0.0737
Brugia malayi hypothetical protein 0.0041 0.0431 0.0433
Schistosoma mansoni glucose transporter 0.0015 0.0051 0.0053
Schistosoma mansoni adrenodoxin 0.0022 0.016 0.0167
Loa Loa (eye worm) hypothetical protein 0.005 0.0562 0.0699
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) CYP4Cod1 0.0069 0.0849 0.1056
Echinococcus granulosus lamin 0.0052 0.0603 0.0626
Schistosoma mansoni slit 0.005 0.0562 0.0584
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0317 0.4489 0.5585
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0022 0.016 0.1046
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0043 0.0458 0.0624
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0413 0.0429
Plasmodium vivax tubulin alpha chain, putative 0.0017 0.0087 0.0408
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.01 0.0091
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0234 0.3266 0.4933
Leishmania major cytochrome p450-like protein 0.0069 0.0849 1
Brugia malayi Tubulin alpha chain 0.0017 0.0087 0.0087
Toxoplasma gondii protease inhibitor PI2 0.0018 0.0104 0.057
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Brugia malayi Nuclear hormone receptor family member nhr-31 0.046 0.6596 0.6638
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) alpha-tubulin 0.0017 0.0087 0.0108
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0648 0.0915
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0043 0.0458 0.0624
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0648 0.0673
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0194 0.0317
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0878 0.0913
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni intermediate filament proteins 0.0052 0.0603 0.0626
Schistosoma mansoni lamin 0.0052 0.0603 0.0626
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0559 0.058
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.162 0.1683
Toxoplasma gondii hypothetical protein 0.0095 0.1226 1
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.016 0.1366
Echinococcus granulosus death domain containing protein 0.0014 0.0037 0.0039
Mycobacterium tuberculosis Possible hydrolase 0.0025 0.0205 0.0336
Loa Loa (eye worm) steroid hormone receptor 0.046 0.6596 0.8207
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0037 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0559 0.0695
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0022 0.016 0.0927
Echinococcus granulosus fmrfamide receptor 0.0022 0.015 0.0156
Brugia malayi Dopamine receptor protein 1 0.0022 0.015 0.0151
Echinococcus multilocularis ferredoxin adrenodoxin 0.0022 0.016 0.0167
Loa Loa (eye worm) fli-1 protein 0.0237 0.332 0.413
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0431 0.0447
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0043 0.0458 0.0889
Onchocerca volvulus 0.0041 0.0431 0.0492
Loa Loa (eye worm) hypothetical protein 0.0052 0.0603 0.075

Activities

Activity type Activity value Assay description Source Reference
HACU improvement (functional) = -13 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-6 M. ChEMBL. No reference
HACU improvement (functional) = -13 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-6 M. ChEMBL. No reference
HACU improvement (functional) = -7 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-5 M. ChEMBL. No reference
HACU improvement (functional) = -7 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-5 M. ChEMBL. No reference
HACU improvement (functional) = 0 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-7 M. ChEMBL. No reference
HACU improvement (functional) = 0 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-7 M. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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