Detailed information for compound 48112

Basic information

Technical information
  • TDR Targets ID: 48112
  • Name: 2-(methylamino)-N-(1,2,3,4-tetrahydroacridin- 9-yl)acetamide
  • MW: 269.342 | Formula: C16H19N3O
  • H donors: 2 H acceptors: 2 LogP: 2.2 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNCC(=O)Nc1c2CCCCc2nc2c1cccc2
  • InChi: 1S/C16H19N3O/c1-17-10-15(20)19-16-11-6-2-4-8-13(11)18-14-9-5-3-7-12(14)16/h2,4,6,8,17H,3,5,7,9-10H2,1H3,(H,18,19,20)
  • InChiKey: GVHIYPXOFUXAIV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(methylamino)-N-(1,2,3,4-tetrahydroacridin-9-yl)ethanamide
  • 2-methylamino-N-(1,2,3,4-tetrahydroacridin-9-yl)acetamide
  • 2-methylamino-N-(1,2,3,4-tetrahydroacridin-9-yl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0438 0.0429
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0095 0.1226 0.1274
Onchocerca volvulus 0.0022 0.015 0.0141
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0191 0.1753
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0043 0.0458 0.0624
Echinococcus granulosus tubulin alpha 1C chain 0.0017 0.0087 0.009
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.3189 0.3313
Brugia malayi laminin alpha chain 0.005 0.0562 0.0565
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) acetyltransferase 0.014 0.189 0.2352
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.016 0.1366
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Toxoplasma gondii cytochrome p450 superfamily protein 0.0043 0.0458 0.3546
Mycobacterium ulcerans oxidoreductase 0.0022 0.016 0.0167
Brugia malayi bHLH-PAS transcription factor 0.007 0.0861 0.0866
Brugia malayi Ets-domain containing protein 0.0078 0.0982 0.0988
Echinococcus granulosus serotonin receptor 0.0022 0.015 0.0156
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Brugia malayi SPARC precursor 0.0018 0.0104 0.0104
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.01 0.0104
Onchocerca volvulus 0.046 0.6596 0.8198
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0013 0.0027 0.0018
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.015 0.0156
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0217 0.3024 0.3762
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0593 0.0737
Loa Loa (eye worm) hypothetical protein 0.0025 0.0205 0.0255
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.057
Echinococcus multilocularis lamin 0.0052 0.0603 0.0626
Onchocerca volvulus 0.0029 0.0266 0.0286
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.015 0.0156
Echinococcus multilocularis follistatin 0.0018 0.0104 0.0108
Echinococcus multilocularis tubulin alpha 3 chain 0.0017 0.0087 0.009
Plasmodium vivax tubulin alpha chain, putative 0.0017 0.0087 0.0408
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0413 0.0429
Leishmania major cytochrome p450-like protein 0.0069 0.0849 1
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0234 0.3266 0.4933
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.01 0.0091
Toxoplasma gondii protease inhibitor PI2 0.0018 0.0104 0.057
Brugia malayi Tubulin alpha chain 0.0017 0.0087 0.0087
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0648 0.0915
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) alpha-tubulin 0.0017 0.0087 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-31 0.046 0.6596 0.6638
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Schistosoma mansoni adrenodoxin 0.0022 0.016 0.0167
Schistosoma mansoni glucose transporter 0.0015 0.0051 0.0053
Brugia malayi hypothetical protein 0.0041 0.0431 0.0433
Loa Loa (eye worm) hypothetical protein 0.005 0.0562 0.0699
Echinococcus granulosus lamin 0.0052 0.0603 0.0626
Loa Loa (eye worm) CYP4Cod1 0.0069 0.0849 0.1056
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0043 0.0458 0.0624
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0022 0.016 0.1046
Loa Loa (eye worm) hypothetical protein 0.0317 0.4489 0.5585
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Schistosoma mansoni slit 0.005 0.0562 0.0584
Echinococcus multilocularis g protein coupled receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0559 0.0695
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0022 0.016 0.0927
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0037 0.0039
Loa Loa (eye worm) steroid hormone receptor 0.046 0.6596 0.8207
Mycobacterium tuberculosis Possible hydrolase 0.0025 0.0205 0.0336
Brugia malayi Dopamine receptor protein 1 0.0022 0.015 0.0151
Echinococcus granulosus fmrfamide receptor 0.0022 0.015 0.0156
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0431 0.0447
Loa Loa (eye worm) fli-1 protein 0.0237 0.332 0.413
Echinococcus multilocularis ferredoxin adrenodoxin 0.0022 0.016 0.0167
Loa Loa (eye worm) hypothetical protein 0.0052 0.0603 0.075
Onchocerca volvulus 0.0041 0.0431 0.0492
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0043 0.0458 0.0889
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0043 0.0458 0.0624
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0648 0.0673
Schistosoma mansoni lamin 0.0052 0.0603 0.0626
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni intermediate filament proteins 0.0052 0.0603 0.0626
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0878 0.0913
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0194 0.0317
Toxoplasma gondii hypothetical protein 0.0095 0.1226 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.162 0.1683
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0559 0.058
Echinococcus granulosus death domain containing protein 0.0014 0.0037 0.0039
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.016 0.1366
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Giardia lamblia Hypothetical protein 0.0025 0.0205 0.4574
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0051 0.0052
Plasmodium vivax hypothetical protein, conserved 0.0095 0.1226 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Onchocerca volvulus 0.0015 0.0051 0.0017
Echinococcus multilocularis solute carrier family 22 0.0015 0.0051 0.0053
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi hypothetical protein 0.0095 0.1226 0.1234
Schistosoma mansoni hypothetical protein 0.0039 0.0413 0.0429
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0194 0.0202
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Mycobacterium ulcerans hypothetical protein 0.0113 0.1486 0.2202
Mycobacterium ulcerans glycolipid sulfotransferase 0.0021 0.0137 0.0132
Echinococcus granulosus FTZ F1 alpha 0.046 0.6596 0.6852
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0043 0.0458 0.0889
Brugia malayi hypothetical protein 0.0024 0.0191 0.0192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0054 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Brugia malayi G-protein coupled receptor 0.0022 0.015 0.0151
Trichomonas vaginalis Ferredoxin 6 0.0022 0.016 0.0151
Loa Loa (eye worm) hypothetical protein 0.0559 0.8038 1
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.015 0.0156
Echinococcus multilocularis solute carrier family 22 0.0015 0.0051 0.0053
Schistosoma mansoni lipoxygenase 0.0041 0.0431 0.0447
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Brugia malayi Serotonin receptor 0.0022 0.015 0.0151
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.015 0.0156
Onchocerca volvulus 0.0022 0.015 0.0141
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1525
Schistosoma mansoni neuropeptide receptor 0.0022 0.015 0.0156
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0022 0.016 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Brugia malayi nuclear hormone receptor family member nhr-6 0.0217 0.3024 0.3043
Brugia malayi alpha-tubulin 0.0017 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus multilocularis solute carrier family 22 0.0015 0.0051 0.0053
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0043 0.0458 0.0624
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.01 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Echinococcus granulosus neuropeptide receptor 0.0022 0.015 0.0156
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0229 0.0231
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.046 0.6596 0.6638
Brugia malayi cytochrome P450 0.0043 0.0458 0.0461
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0326 0.4627 1
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.162 0.1683
Brugia malayi Nuclear hormone receptor family member nhr-3 0.046 0.6596 0.6638
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.1833 0.1904
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0266 0.0276
Echinococcus multilocularis 0.0043 0.0458 0.0476
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0136 0.0127
Echinococcus granulosus neurogenic locus notch protein 0.005 0.0562 0.0584
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Schistosoma mansoni hypothetical protein 0.0043 0.0458 0.0476
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.015 0.0156
Brugia malayi hypothetical protein 0.0027 0.0229 0.0231
Brugia malayi hypothetical protein 0.02 0.2776 0.2794
Leishmania major ferredoxin 2fe-2s-like protein 0.0022 0.016 0.1366
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Echinococcus granulosus single minded 2 0.007 0.0861 0.0894
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.015 0.0156
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0217 0.3024 0.3141
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0243 0.3406 0.3538
Brugia malayi hypothetical protein 0.0217 0.3024 0.3043
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1525
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0051 0.0064
Echinococcus granulosus sodium and chloride dependent glycine 0.0095 0.1226 0.1274
Onchocerca volvulus 0.0027 0.0229 0.024
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.015 0.0156
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0713 0.0741
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0014 0.0039 0.0049
Schistosoma mansoni nuclear receptor 0.0217 0.3024 0.3141
Brugia malayi hypothetical protein 0.0243 0.3406 0.3428
Onchocerca volvulus 0.0095 0.1226 0.1486
Brugia malayi GnHR receptor homolog 0.0022 0.015 0.0151
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0266 0.0276
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0438 0.3382
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.01 0.0419
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0849 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) RNA binding protein 0.013 0.1737 0.2161
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0217 0.3024 0.3141
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0191 0.119
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0217 0.3024 0.3141
Echinococcus granulosus somatostatin receptor 0.0022 0.015 0.0156
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.01 0.0417
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.046 0.6596 0.6852
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.046 0.6596 0.6852
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.016 0.1366
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Mycobacterium ulcerans arylsulfatase AtsD 0.0025 0.0205 0.0236
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.015 0.0156
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0232 0.1648
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.057
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0022 0.016 0.0167
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0025 0.0205 0.0336
Leishmania major cytochrome p450-like protein 0.0043 0.0458 0.5098
Onchocerca volvulus 0.0022 0.015 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0051 0.0053
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Onchocerca volvulus 0.0559 0.8038 1
Trypanosoma brucei alpha tubulin 0.0017 0.0087 0.0443
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0043 0.0458 0.0624
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Onchocerca volvulus 0.0015 0.0051 0.0017
Schistosoma mansoni myosin xvIII 0.0022 0.015 0.0156
Echinococcus multilocularis Tubulin alpha 1 chain 0.0017 0.0087 0.009
Schistosoma mansoni cpg binding protein 0.0029 0.0264 0.0274
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Schistosoma mansoni ets-related 0.0237 0.332 0.3449
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Brugia malayi nuclear receptor NHR-88 0.046 0.6596 0.6638
Echinococcus granulosus solute carrier family 22 0.0015 0.0051 0.0053
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0431 0.0447
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.01 0.0104
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.015 0.0156
Schistosoma mansoni sugar transporter 0.0015 0.0051 0.0053
Echinococcus granulosus jun protein 0.0255 0.3581 0.372
Echinococcus granulosus pikachurin 0.005 0.0562 0.0584
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0022 0.016 0.0154
Toxoplasma gondii hypothetical protein 0.0095 0.1226 1
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0051 0.0042
Onchocerca volvulus 0.0015 0.0051 0.0017
Loa Loa (eye worm) hypothetical protein 0.005 0.0562 0.0699
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Brugia malayi Nuclear hormone receptor E75 0.0217 0.3024 0.3043
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0043 0.0458 0.0889
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.015 0.0156
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0191 0.1305
Brugia malayi Nuclear hormone receptor family member nhr-40 0.046 0.6596 0.6638
Brugia malayi Sulfotransferase domain containing protein 0.0021 0.0137 0.0138
Echinococcus granulosus slit 2 protein 0.005 0.0562 0.0584
Echinococcus granulosus solute carrier family 22 0.0015 0.0051 0.0053
Mycobacterium ulcerans oxidoreductase 0.0022 0.016 0.0167
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0194 0.0185
Echinococcus granulosus nuclear receptor 2DBD gamma 0.046 0.6596 0.6852
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0043 0.0458 0.0889
Trypanosoma brucei alpha tubulin 0.0017 0.0087 0.0443
Echinococcus multilocularis sodium and chloride dependent glycine 0.0095 0.1226 0.1274
Echinococcus granulosus solute carrier family 22 0.0015 0.0051 0.0053
Loa Loa (eye worm) hypothetical protein 0.0067 0.0815 0.1014
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0243 0.3406 0.3538
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.015 0.0151
Onchocerca volvulus 0.0015 0.0051 0.0017
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.046 0.6596 0.6852
Echinococcus multilocularis nuclear receptor nhr 48 0.0217 0.3024 0.3141
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi hypothetical protein 0.0016 0.0064 0.0065
Loa Loa (eye worm) hypoxia-induced factor 1 0.0292 0.4129 0.5137
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0043 0.0458 0.0889
Plasmodium falciparum alpha tubulin 1 0.0017 0.0087 0.0301
Brugia malayi hypothetical protein 0.0027 0.0229 0.0231
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi Pre-SET motif family protein 0.0029 0.0266 0.0268
Brugia malayi sulfakinin receptor protein 0.0022 0.015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Giardia lamblia Alpha-tubulin 0.0017 0.0087 0.1049
Echinococcus multilocularis solute carrier family 22 0.0015 0.0051 0.0053
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0055 0.0648 0.0673
Loa Loa (eye worm) intermediate filament protein 0.0052 0.0603 0.075
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Schistosoma mansoni aryl hydrocarbon receptor 0.0094 0.1221 0.1269
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.046 0.6596 0.6852
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Trichomonas vaginalis aldehyde oxidase, putative 0.0692 1 1
Echinococcus granulosus RUN 0.0041 0.0431 0.0447
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Brugia malayi secreted modular calcium-binding protein 1 0.0018 0.0104 0.0104
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0431 0.3304
Onchocerca volvulus 0.0025 0.0194 0.0196
Brugia malayi steroid hormone receptor 0.046 0.6596 0.6638
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0037 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.046 0.6596 0.6638
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0217 0.3024 0.3141
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0039 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Brugia malayi tubulin alpha chain - mouse 0.0017 0.0087 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.046 0.6596 0.8207
Schistosoma mansoni opsin-like receptor 0.0022 0.015 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Treponema pallidum sodium- and chloride- dependent transporter 0.0559 0.8038 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Schistosoma mansoni lipoxygenase 0.0114 0.1506 0.1564
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Toxoplasma gondii ferredoxin, putative 0.0022 0.016 0.1046
Brugia malayi intermediate filament protein 0.0052 0.0603 0.0607
Schistosoma mansoni adrenodoxin 0.0022 0.016 0.0167
Loa Loa (eye worm) solute carrier family 6 member 4 0.0559 0.8038 1
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0229 0.024
Onchocerca volvulus Protein ultraspiracle homolog 0.046 0.6596 0.8198
Echinococcus granulosus ferredoxin 0.0022 0.016 0.0167
Loa Loa (eye worm) hypothetical protein 0.0248 0.3478 0.4328
Loa Loa (eye worm) cytochrome P450 family protein 0.0158 0.2158 0.2685
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0243 0.3406 0.3538
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.015 0.0156
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0022 0.016 0.0199
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Echinococcus multilocularis Ankyrin 0.0014 0.0039 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0051 0.0589 0.0732
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.015 0.0141
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0217 0.3024 0.3043
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0043 0.0458 0.0624
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.015 0.0156
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.046 0.6596 0.8207
Mycobacterium ulcerans electron transfer protein 0.0022 0.016 0.0167
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0194 0.0185
Schistosoma mansoni thyroid hormone receptor 0.0582 0.8383 0.8708
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Trypanosoma brucei cytochrome P450, putative 0.0069 0.0849 1
Brugia malayi major facilitator superfamily protein 0.0015 0.0051 0.0052
Loa Loa (eye worm) hypothetical protein 0.0228 0.3189 0.3968
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.015 0.0156
Plasmodium falciparum amino acid transporter, putative 0.0095 0.1226 1
Echinococcus granulosus Adrenodoxin mitochondrial 0.0022 0.016 0.0167
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0217 0.3024 0.3141
Giardia lamblia Alpha-tubulin 0.0017 0.0087 0.1049
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0266 0.0276
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-49 0.046 0.6596 0.6638
Onchocerca volvulus Putative transporter 0.0015 0.0051 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) alpha-tubulin 0.0017 0.0087 0.0108
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Brugia malayi bZIP transcription factor family protein 0.0255 0.3581 0.3604
Schistosoma mansoni opsin-like receptor 0.0022 0.015 0.0156
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.015 0.0156
Onchocerca volvulus 0.0015 0.0051 0.0017
Brugia malayi nuclear hormone receptor family member odr-7 0.0217 0.3024 0.3043
Echinococcus multilocularis serotonin receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0104 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0051 0.0052
Echinococcus multilocularis neurogenic locus notch protein 0.005 0.0562 0.0584
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trichomonas vaginalis Ferredoxin 7 0.0022 0.016 0.0151
Schistosoma mansoni biogenic amine receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.046 0.6596 0.8198
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0043 0.0458 0.0624
Mycobacterium ulcerans oxygenase 0.0022 0.016 0.0167
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0095 0.1226 0.1274
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0241 0.03
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni tubulin subunit alpha 0.0017 0.0087 0.009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.046 0.6596 0.6852
Brugia malayi Cytochrome P450 family protein 0.0069 0.0849 0.0854
Echinococcus multilocularis RUN 0.0041 0.0431 0.0447
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni neuropeptide receptor 0.0022 0.015 0.0156
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.046 0.6596 0.6852
Brugia malayi neuropeptide F receptor 0.0022 0.015 0.0151
Onchocerca volvulus 0.0052 0.0603 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0194 0.0185
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0022 0.016 1
Brugia malayi Dopamine receptor protein 2 0.0022 0.015 0.0151
Brugia malayi Uncoordinated protein 44 0.0014 0.0037 0.0038
Echinococcus multilocularis orexin receptor type 2 0.0022 0.015 0.0156
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus tubulin alpha 1C chain 0.0017 0.0087 0.009
Onchocerca volvulus 0.0015 0.0051 0.0017
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Echinococcus granulosus orexin receptor type 2 0.0022 0.015 0.0156
Brugia malayi Sulfotransferase domain containing protein 0.0021 0.0137 0.0138
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.1226 1
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Echinococcus granulosus g protein coupled receptor 0.0022 0.015 0.0156
Trichomonas vaginalis tubulin epsilon chain, putative 0.0017 0.0087 0.0077
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.015 0.0156
Schistosoma mansoni cytochrome P450 0.0043 0.0458 0.0476
Loa Loa (eye worm) hypothetical protein 0.0021 0.0137 0.0171
Schistosoma mansoni alpha tubulin 0.0017 0.0087 0.009
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.015 0.0186
Onchocerca volvulus 0.023 0.3205 0.396
Trypanosoma brucei electron transfer protein, putative 0.0022 0.016 0.1366
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0243 0.3406 0.3538
Brugia malayi Sugar transporter family protein 0.0015 0.0051 0.0052
Brugia malayi major facilitator superfamily protein 0.0015 0.0051 0.0052
Schistosoma mansoni jun-related protein 0.0207 0.2879 0.2991
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0194 0.0185
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0229 0.0238
Brugia malayi nuclear hormone receptor 0.046 0.6596 0.6638
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.015 0.0156
Plasmodium vivax tubulin alpha chain, putative 0.0017 0.0087 0.0408
Echinococcus multilocularis somatostatin receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0041 0.0431 0.0536
Schistosoma mansoni gabp alpha 0.0078 0.0982 0.102
Echinococcus granulosus sex peptide receptor 0.0022 0.015 0.0156
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.015 0.0156
Schistosoma mansoni biogenic amine receptor 0.0022 0.015 0.0156
Brugia malayi nuclear receptor NHR-67 0.0217 0.3024 0.3043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.015 0.0156
Treponema pallidum quinoline 2-oxidoreductase 0.011 0.1448 0.1697
Entamoeba histolytica hypothetical protein 0.0039 0.0413 1
Schistosoma mansoni coup transcription factor 0.046 0.6596 0.6852
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0013 0.0027 0.0034
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.1528 0.1901
Schistosoma mansoni histamine h1 receptor 0.0022 0.015 0.0156
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.015 0.0156
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0229 0.0231
Schistosoma mansoni Tr4/Tr2 (homologue) 0.046 0.6596 0.6852
Brugia malayi CXXC zinc finger family protein 0.0028 0.0241 0.0243
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0559 0.058
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0069 0.0849 0.1224
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0043 0.0458 0.0624
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus granulosus tubulin alpha 3 chain 0.0017 0.0087 0.009
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0246 0.0306
Echinococcus multilocularis neuropeptide s receptor 0.0022 0.015 0.0156
Schistosoma mansoni hypothetical protein 0.0395 0.5638 0.5857
Brugia malayi neuropeptide F receptor 0.0022 0.015 0.0151
Mycobacterium ulcerans arylsulfatase, AslA 0.0025 0.0205 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Echinococcus granulosus Tubulin alpha 1 chain 0.0017 0.0087 0.009
Trypanosoma brucei alpha tubulin 0.0017 0.0087 0.0443
Loa Loa (eye worm) cytochrome P450 0.0043 0.0458 0.057
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.015 0.0151
Schistosoma mansoni loxhd1 0.0041 0.0431 0.0447
Schistosoma mansoni rab6-interacting 0.0041 0.0431 0.0447
Loa Loa (eye worm) sugar transporter 0.0015 0.0051 0.0064
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0017 0.0087 0.0077
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1234
Loa Loa (eye worm) hypothetical protein 0.0016 0.0075 0.0093
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0878 0.0913
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0388 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.015 0.0156
Onchocerca volvulus 0.0028 0.0241 0.0254
Onchocerca volvulus 0.0047 0.0518 0.0601
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Plasmodium falciparum alpha tubulin 2 0.0017 0.0087 0.0301
Brugia malayi Intermediate filament tail domain containing protein 0.0052 0.0603 0.0607
Onchocerca volvulus 0.0015 0.0051 0.0017
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0095 0.1226 0.1274
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0559 0.058
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.015 0.0186
Plasmodium vivax sugar transporter, putative 0.0015 0.0051 0.0111
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0136 0.0137
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.046 0.6596 0.6852
Echinococcus granulosus Tubulin alpha 1 chain 0.0017 0.0087 0.009
Onchocerca volvulus 0.0015 0.0051 0.0017
Mycobacterium ulcerans glycolipid sulfotransferase 0.0021 0.0137 0.0132
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0194 0.179
Onchocerca volvulus 0.02 0.2776 0.3424
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0025 0.0205 0.0196
Echinococcus multilocularis Tubulin alpha 1 chain 0.0017 0.0087 0.009
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0136 0.0127
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.015 0.0151
Onchocerca volvulus 0.0022 0.016 0.0154
Schistosoma mansoni hypothetical protein 0.0015 0.0051 0.0053
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0438 0.3368
Schistosoma mansoni nuclear hormone receptor 0.0217 0.3024 0.3141
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0194 0.0185
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.01 0.0614
Onchocerca volvulus 0.0217 0.3024 0.3733
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.015 0.0156
Schistosoma mansoni thyroid hormone receptor 0.0582 0.8383 0.8708
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.015 0.0156
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0431 0.0447
Schistosoma mansoni cpg binding protein 0.0028 0.0241 0.025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0205 0.0255
Loa Loa (eye worm) RecQ helicase 0.0021 0.0136 0.017
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Treponema pallidum hypothetical protein 0.0093 0.1194 0.1378
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0043 0.0458 0.0889
Brugia malayi ORL1-like opioid receptor 0.0022 0.015 0.0151
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0051 0.0064
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.005 0.0562 0.0584
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.015 0.0156
Loa Loa (eye worm) DR-78 0.0217 0.3024 0.3762
Toxoplasma gondii ferodoxin FD 0.0022 0.016 0.1046
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Onchocerca volvulus 0.0217 0.3024 0.3733
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.2796 0.3478
Giardia lamblia [2Fe-2S] ferredoxin 0.0022 0.016 0.3237
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0326 0.4627 0.7021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0648 0.0915
Schistosoma mansoni single-minded 0.0094 0.1221 0.1269
Onchocerca volvulus 0.0021 0.0137 0.0125
Toxoplasma gondii exonuclease III APE 0.0018 0.01 0.0542
Brugia malayi Tubulin alpha-2 chain 0.0017 0.0087 0.0087
Echinococcus granulosus neuropeptide receptor 0.0022 0.015 0.0156
Schistosoma mansoni hypothetical protein 0.0207 0.2879 0.2991
Onchocerca volvulus 0.0022 0.015 0.0141
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0229 0.024
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.015 0.0186
Schistosoma mansoni tubulin subunit alpha 0.0017 0.0087 0.009
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi ecdysone receptor 0.0217 0.3024 0.3043
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0043 0.0458 0.0624
Brugia malayi Death domain containing protein 0.0014 0.0037 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi hypothetical protein 0.0015 0.0051 0.0052
Echinococcus granulosus tubulin subunit TubB 0.0017 0.0087 0.009
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0255 0.3581 0.372
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Leishmania major protein kinase, putative 0.0025 0.0194 0.179
Loa Loa (eye worm) nuclear receptor NHR-67 0.0217 0.3024 0.3762
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.01 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Trichomonas vaginalis Ferredoxin 4 0.0022 0.016 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0217 0.3024 0.3141
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0431 0.0447
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.015 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Echinococcus granulosus g protein coupled receptor 0.0022 0.015 0.0156
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0095 0.1226 0.1274
Brugia malayi G protein-coupled receptor 0.0022 0.015 0.0151
Brugia malayi hypothetical protein 0.0015 0.0051 0.0052
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.015 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0043 0.0458 0.0889
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0326 0.4627 0.7021
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Echinococcus granulosus allatostatin A receptor 0.0022 0.015 0.0156
Echinococcus multilocularis hypothetical protein 0.0017 0.0087 0.009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0224 0.0279
Onchocerca volvulus 0.0015 0.0051 0.0017
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0051 0.0131
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0266 0.0276
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0849 0.1056
Brugia malayi RNA recognition motif domain containing protein 0.013 0.1737 0.1748
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus follistatin 0.0018 0.0104 0.0108
Echinococcus multilocularis sex peptide receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.046 0.6596 0.6638
Brugia malayi AKH receptor 0.0022 0.015 0.0151
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.015 0.0156
Brugia malayi EGF-like domain containing protein 0.005 0.0562 0.0565
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.015 0.0156
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0099 0.041
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.015 0.0156
Schistosoma mansoni sodium/chloride dependent transporter 0.0095 0.1226 0.1274
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.015 0.0156
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0024 0.0191 0.0237
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0104 0.0104
Schistosoma mansoni sodium-dependent amino acid transporter 0.0095 0.1226 0.1274
Brugia malayi larval opioid receptor 0.0022 0.015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0043 0.0458 0.0624
Echinococcus granulosus Nuclear hormone receptor HR96 0.0217 0.3024 0.3141
Onchocerca volvulus 0.0015 0.0051 0.0017
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Onchocerca volvulus Bile acid receptor homolog 0.046 0.6596 0.8198
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0025 0.0194 0.179
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0229 0.024
Echinococcus granulosus bifunctional heparan sulfate 0.0021 0.0137 0.0143
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.046 0.6596 0.8207
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.015 0.0156
Entamoeba histolytica hypothetical protein 0.0039 0.0413 1
Echinococcus multilocularis cpg binding protein 0.0029 0.0264 0.0274
Echinococcus multilocularis agrin 0.0018 0.0104 0.0108
Mycobacterium tuberculosis Possible oxygenase 0.0022 0.016 0.0238
Brugia malayi putative neuropeptide receptor 0.0022 0.015 0.0151
Trichomonas vaginalis Ferredoxin 2 0.0022 0.016 0.0151
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.015 0.0156
Schistosoma mansoni alpha tubulin 0.0017 0.0087 0.009
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0025 0.0194 0.179
Echinococcus granulosus peroxisome assembly protein 26 0.0017 0.0087 0.009
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.1506 0.1564
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0025 0.0194 0.179
Echinococcus granulosus nuclear receptor nhr 48 0.0217 0.3024 0.3141
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.015 0.0156
Schistosoma mansoni sodium/chloride dependent transporter 0.0095 0.1226 0.1274
Echinococcus multilocularis g protein coupled receptor 0.0022 0.015 0.0156
Brugia malayi nuclear hormone receptor 0.0217 0.3024 0.3043
Schistosoma mansoni tubulin subunit alpha 0.0017 0.0087 0.009
Brugia malayi hypothetical protein 0.0039 0.0413 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Onchocerca volvulus 0.0022 0.015 0.0141
Leishmania major cytochrome p450-like protein 0.0043 0.0458 0.5098
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0055 0.0648 0.7475
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0458 0.5098
Schistosoma mansoni glucose transport protein 0.0015 0.0051 0.0053
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.01 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0104 0.0104
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0043 0.0458 0.0889
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0037 0.0038
Brugia malayi tubulin alpha-2 chain 0.0017 0.0087 0.0087
Schistosoma mansoni adenoreceptor 0.0022 0.015 0.0156
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0022 0.016 0.1366
Brugia malayi Dopamine receptor 0.0022 0.015 0.0151
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0095 0.1226 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.01 0.0614
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0025 0.0205 0.0255
Echinococcus multilocularis Tubulin alpha 1 chain 0.0017 0.0087 0.009
Trypanosoma cruzi alpha tubulin, putative 0.0017 0.0087 0.0443
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.046 0.6596 0.8207
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0241 0.0251
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0043 0.0458 0.0624
Loa Loa (eye worm) hypothetical protein 0.005 0.0562 0.0699
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0095 0.1226 0.1234
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus solute carrier family 22 0.0015 0.0051 0.0053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Onchocerca volvulus 0.0095 0.1226 0.1486
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0266 0.0276
Echinococcus multilocularis sodium and chloride dependent glycine 0.0095 0.1226 0.1274
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1234
Echinococcus multilocularis fmrfamide receptor 0.0022 0.015 0.0156
Brugia malayi Serotonin receptor 0.0022 0.015 0.0151
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.015 0.0156
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.189 0.1964
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.046 0.6596 0.8207
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0054 0.0004
Onchocerca volvulus 0.0015 0.0051 0.0017
Brugia malayi nuclear receptor RXR 0.0243 0.3406 0.3428
Echinococcus granulosus lamin dm0 0.0052 0.0603 0.0626
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.015 0.0156
Echinococcus granulosus retinoic acid receptor rxr beta a 0.046 0.6596 0.6852
Loa Loa (eye worm) tubulin alpha-2 chain 0.0017 0.0087 0.0108
Brugia malayi Pre-SET motif family protein 0.0202 0.2796 0.2814
Leishmania major protein kinase, putative 0.0025 0.0194 0.179
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0229 0.0285
Brugia malayi photoreceptor-specific nuclear receptor 0.046 0.6596 0.6638
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0243 0.3406 0.4238
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.0129
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0037 0.0047
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.01 0.0107
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi prostaglandin transporter 0.0027 0.0229 0.0231
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.015 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Onchocerca volvulus 0.0022 0.015 0.0141
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0559 0.058
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0194 0.0185
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0458 0.6568 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0194 0.0185
Brugia malayi nuclear receptor NHR-88 0.0217 0.3024 0.3043
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0022 0.016 0.0238
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0431 0.0447
Echinococcus granulosus sodium and chloride dependent glycine 0.0095 0.1226 0.1274
Onchocerca volvulus 0.0022 0.015 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0266 0.1934
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.016 0.1366
Loa Loa (eye worm) hypothetical protein 0.0024 0.0191 0.0238
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.046 0.6596 0.6852
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.1226 0.1234
Echinococcus multilocularis musashi 0.0052 0.0603 0.0626
Loa Loa (eye worm) hypothetical protein 0.0025 0.0194 0.0241
Brugia malayi hypoxia-induced factor 1 0.0292 0.4129 0.4155
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Echinococcus multilocularis expressed protein 0.0018 0.0104 0.0108
Schistosoma mansoni nuclear receptor nhr-48 0.0217 0.3024 0.3141
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0043 0.0458 0.0889
Schistosoma mansoni hypothetical protein 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni glucose transport protein 0.0015 0.0051 0.0053
Echinococcus multilocularis serotonin transporter 0.0559 0.8038 0.835
Plasmodium falciparum ferredoxin, putative 0.0022 0.016 0.0927
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.015 0.0156
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0648 0.0673
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0043 0.0458 0.0624
Echinococcus multilocularis neuropeptide receptor 0.0022 0.015 0.0156
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0055 0.0648 0.1303
Schistosoma mansoni RAR-like nuclear receptor 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0266 0.0276
Schistosoma mansoni hypothetical protein 0.0122 0.162 0.1683
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.016 0.1366
Schistosoma mansoni neuropeptide receptor 0.0022 0.015 0.0156
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.0458 0.5098
Schistosoma mansoni ap endonuclease 0.0018 0.01 0.0104
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.057
Brugia malayi Protein kinase domain containing protein 0.0014 0.0037 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-25 0.046 0.6596 0.6638
Onchocerca volvulus 0.0015 0.0051 0.0017
Onchocerca volvulus 0.0052 0.0603 0.0707
Echinococcus granulosus ecdysone induced protein 78C 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0025 0.0194 0.179
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0043 0.0458 0.0624
Schistosoma mansoni organic anion transporter 0.0027 0.0229 0.0238
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0559 0.0562
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0191 0.1753
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0205 0.0213
Echinococcus multilocularis tubulin alpha chain 0.0017 0.0087 0.009
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0849 0.1056
Schistosoma mansoni nuclear hormone receptor 0.0217 0.3024 0.3141
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0194 0.0202
Trichomonas vaginalis set domain proteins, putative 0.0229 0.3204 0.3197
Echinococcus granulosus neuropeptide receptor A26 0.0022 0.015 0.0156
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.015 0.0156
Echinococcus granulosus Ankyrin 0.0014 0.0039 0.0041
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0018 0.0104 0.057
Echinococcus multilocularis ecdysone induced protein 78C 0.046 0.6596 0.6852
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.046 0.6596 0.8207
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.015 0.0156
Plasmodium vivax hexose transporter 0.0015 0.0051 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0194 0.0185
Onchocerca volvulus 0.0015 0.0051 0.0017
Entamoeba histolytica hypothetical protein 0.0039 0.0413 1
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0132 0.1774 0.2644
Onchocerca volvulus 0.0022 0.015 0.0141
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Trypanosoma brucei alpha tubulin 0.0017 0.0087 0.0443
Schistosoma mansoni polycystin 1-related 0.0041 0.0431 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Toxoplasma gondii alpha tubulin TUBA1 0.0017 0.0087 0.0427
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0025 0.0205 0.0336
Echinococcus multilocularis FTZ F1 alpha 0.046 0.6596 0.6852
Brugia malayi hypothetical protein 0.0217 0.3024 0.3043
Loa Loa (eye worm) serotonin transporter b 0.0559 0.8038 1
Onchocerca volvulus 0.007 0.0861 0.1029
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0136 0.0142
Schistosoma mansoni organic anion transporter 0.0027 0.0229 0.0238
Mycobacterium tuberculosis Probable sulfatase 0.0025 0.0205 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.015 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Echinococcus granulosus hypothetical protein 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0017 0.0087 0.0108
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0051 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0559 0.8038 0.835
Brugia malayi Nuclear hormone receptor family member nhr-41 0.046 0.6596 0.6638
Mycobacterium ulcerans arylsulfatase AtsB 0.0025 0.0205 0.0236
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0043 0.0458 0.0889
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0388 0.2865
Brugia malayi Steroid receptor seven-up type 2 0.046 0.6596 0.6638
Onchocerca volvulus 0.0022 0.015 0.0141
Trichomonas vaginalis tubulin epsilon chain, putative 0.0017 0.0087 0.0077
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Brugia malayi tailless protein 0.0217 0.3024 0.3043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0559 0.058
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Brugia malayi hypothetical protein 0.0228 0.3189 0.3209
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.015 0.0156
Brugia malayi orphan nuclear receptor NR2E1 0.0217 0.3024 0.3043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0104 0.0129
Echinococcus multilocularis peroxisome assembly protein 26 0.0017 0.0087 0.009
Loa Loa (eye worm) abnormal epIthelia family member 0.005 0.0562 0.0699
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0073 0.0075
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0217 0.3024 0.3141
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.015 0.0156
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.015 0.0156
Echinococcus granulosus bloom syndrome protein 0.0021 0.0136 0.0142
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Echinococcus granulosus serotonin transporter 0.0559 0.8038 0.835
Echinococcus granulosus thyroid hormone receptor alpha 0.0217 0.3024 0.3141
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0043 0.0458 0.0889
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Loa Loa (eye worm) sugar transporter 0.0015 0.0051 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0559 0.8038 1
Schistosoma mansoni hypothetical protein 0.0022 0.015 0.0156
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Echinococcus multilocularis GA binding protein alpha chain 0.0078 0.0982 0.102
Schistosoma mansoni heparan sulfate n-deacetylase/n-sulfotransferase 0.0021 0.0137 0.0143
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0043 0.0458 0.0889
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.015 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0217 0.3024 0.3141
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0043 0.0458 0.0624
Schistosoma mansoni sugar transporter 0.0015 0.0051 0.0053
Echinococcus multilocularis tubulin subunit TubB 0.0017 0.0087 0.009
Echinococcus granulosus alpha tubulin 0.0017 0.0087 0.009
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0194 0.0241
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0132 0.1774 0.3766
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.015 0.0156
Schistosoma mansoni netrin receptor unc5 0.0014 0.0037 0.0039
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.1226 1
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0054 0.0056
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.015 0.0186
Trichomonas vaginalis Ferredoxin 1 0.0022 0.016 0.0151
Schistosoma mansoni glucose transport protein 0.0015 0.0051 0.0053
Schistosoma mansoni hypothetical protein 0.0014 0.0037 0.0039
Brugia malayi Cytochrome P450 family protein 0.0043 0.0458 0.0461
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.015 0.0156
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0194 0.0185
Plasmodium vivax ferredoxin, putative 0.0022 0.016 0.1028
Entamoeba histolytica hypothetical protein 0.0039 0.0413 1
Brugia malayi hypothetical protein 0.0243 0.3406 0.3428
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Toxoplasma gondii sugar transporter ST1 0.0015 0.0051 0.0131
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.015 0.0156
Schistosoma mansoni hypothetical protein 0.0041 0.0431 0.0447
Loa Loa (eye worm) hypothetical protein 0.0041 0.0431 0.0536
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.015 0.0156
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0015 0.0051 0.0053
Echinococcus granulosus GA binding protein alpha chain 0.0078 0.0982 0.102
Schistosoma mansoni agrin 0.0018 0.0104 0.0108
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0229 0.0238
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0672 0.5341
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0043 0.0458 0.0889
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.046 0.6596 0.8207
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0015 0.0054 0.0067
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0388 0.9239
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.015 0.0156
Schistosoma mansoni sodium/chloride dependent transporter 0.0559 0.8038 0.835
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi hypothetical protein 0.0025 0.0205 0.0207
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0194 0.179
Loa Loa (eye worm) tubulin alpha 2 0.0013 0.0027 0.0034
Loa Loa (eye worm) TAR-binding protein 0.013 0.1737 0.2161
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Onchocerca volvulus 0.0022 0.015 0.0141
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Schistosoma mansoni neuropeptide receptor 0.0022 0.015 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0205 0.0213
Echinococcus granulosus agrin 0.0018 0.0104 0.0108
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0043 0.0458 0.0889
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0229 0.0238
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0104 0.0129
Echinococcus multilocularis allatostatin A receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0244 0.3414 0.4248
Onchocerca volvulus 0.0027 0.0229 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Schistosoma mansoni nuclear hormone receptor 0.046 0.6596 0.6852
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0438 0.0429
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0413 0.0429
Echinococcus multilocularis bifunctional heparan sulfate 0.0021 0.0137 0.0143
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0559 0.058
Schistosoma mansoni opsin-like receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0194 0.0185
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.005 0.0562 0.0565
Brugia malayi Fli-1 protein 0.0237 0.332 0.3341
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.01 0.0075
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0692 1 1
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0431 0.3229
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi Ets-domain containing protein 0.0078 0.0982 0.0988
Brugia malayi Sugar transporter family protein 0.0015 0.0051 0.0052
Brugia malayi Nuclear hormone receptor-like 1 0.0243 0.3406 0.3428
Toxoplasma gondii facilitative glucose transporter GT1 0.0015 0.0051 0.0131
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0217 0.3024 0.3733
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0285
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0191 0.1288
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0648 0.0652
Schistosoma mansoni hypothetical protein 0.0022 0.015 0.0156
Plasmodium vivax amine transporter, putative 0.0095 0.1226 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0191 0.0237
Giardia lamblia Hypothetical protein 0.0025 0.0205 0.4574
Mycobacterium ulcerans sulfatase 0.0025 0.0205 0.0236
Schistosoma mansoni nuclear receptor 0.0217 0.3024 0.3141
Brugia malayi hypothetical protein 0.0015 0.0051 0.0052
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0559 0.8038 0.8089
Echinococcus multilocularis serotonin receptor 0.0022 0.015 0.0156
Brugia malayi Melatonin receptor type 1A 0.0022 0.015 0.0151
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Brugia malayi Nuclear hormone receptor E75 0.0217 0.3024 0.3043
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.015 0.0156
Onchocerca volvulus 0.0022 0.015 0.0141
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0052 0.0603 0.075
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0559 0.058
Onchocerca volvulus 0.0027 0.0229 0.024
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.015 0.0151
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0229 0.2229
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0043 0.0458 0.0624
Brugia malayi Nuclear hormone receptor-like 1 0.0243 0.3406 0.3428
Echinococcus multilocularis tubulin alpha 1C chain 0.0017 0.0087 0.009
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0229 0.0231
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.015 0.0156
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Leishmania major hypothetical protein, conserved 0.0022 0.016 0.1366
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.015 0.0151
Echinococcus multilocularis jun protein 0.0255 0.3581 0.372
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0438 0.3382
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.01 0.0101
Echinococcus multilocularis neuropeptide receptor A26 0.0022 0.015 0.0156
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0043 0.0458 0.5098
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Echinococcus granulosus g protein coupled receptor 0.0022 0.015 0.0156
Schistosoma mansoni retinoic acid receptor RXR 0.046 0.6596 0.6852
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Schistosoma mansoni tar DNA-binding protein 0.013 0.1737 0.1804
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0025 0.0205 0.021
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Brugia malayi PAS domain containing protein 0.0094 0.1221 0.1229
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.046 0.6596 0.6852
Mycobacterium ulcerans arylsulfatase AtsD 0.0025 0.0205 0.0236
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0246 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0217 0.3024 0.3733
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.3189 0.3313
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0104 0.0104
Brugia malayi ecdysteroid receptor 0.046 0.6596 0.6638
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0095 0.1226 0.1274
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.015 0.0156
Echinococcus granulosus neuropeptide s receptor 0.0022 0.015 0.0156
Brugia malayi G-protein coupled receptor 0.0022 0.015 0.0151
Echinococcus multilocularis slit 2 protein 0.005 0.0562 0.0584
Brugia malayi RE15519p 0.0022 0.015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0012
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0548 0.7881 0.9805
Echinococcus multilocularis lamin dm0 0.0052 0.0603 0.0626
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Toxoplasma gondii alpha-tubulin I, putative 0.0017 0.0087 0.0427
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0194 0.0202
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Plasmodium vivax SET domain protein, putative 0.0029 0.0266 0.1917
Onchocerca volvulus 0.0041 0.0431 0.0492
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.015 0.0151
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0043 0.0458 0.0889
Brugia malayi follicle stimulating hormone receptor 0.0244 0.3414 0.3436
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0095 0.1226 0.1274
Loa Loa (eye worm) hypothetical protein 0.0243 0.3406 0.4238
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Brugia malayi RNA binding protein 0.013 0.1737 0.1748
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.046 0.6596 0.6852
Schistosoma mansoni hypothetical protein 0.0047 0.0518 0.0538
Schistosoma mansoni hypothetical protein 0.0022 0.015 0.0156
Loa Loa (eye worm) norepinephrine transporter 0.0559 0.8038 1
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.9626 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0043 0.0458 0.0624
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Schistosoma mansoni cell polarity protein 0.005 0.0562 0.0584
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.1506 0.1564
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0018 0.0104 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Brugia malayi MH2 domain containing protein 0.0115 0.1528 0.1537
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.9626 1
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.016 0.1366
Schistosoma mansoni survival motor neuron protein 0.0047 0.0518 0.0538
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Schistosoma mansoni rab6-interacting 0.0041 0.0431 0.0447
Mycobacterium leprae Conserved hypothetical protein 0.0043 0.0458 1
Schistosoma mansoni follistatin 0.0018 0.0104 0.0108
Onchocerca volvulus 0.0022 0.015 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) tubulin alpha chain 0.0017 0.0087 0.0108
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Echinococcus multilocularis tar DNA binding protein 0.013 0.1737 0.1804
Leishmania major hypothetical protein, conserved 0.0024 0.0191 0.1753
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.015 0.0151
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0037 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0043 0.0458 0.0889
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0132 0.1774 0.2644
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0217 0.3024 0.3141
Echinococcus granulosus cpg binding protein 0.0029 0.0264 0.0274
Echinococcus granulosus g-protein coupled receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni sugar transporter 0.0015 0.0051 0.0053
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0043 0.0458 0.0624
Mycobacterium ulcerans glycolipid sulfotransferase 0.0021 0.0137 0.0132
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0438 0.0455
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.015 0.0156
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.015 0.0156
Echinococcus granulosus dnaJ subfamily B 0.0395 0.5638 0.5857
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Onchocerca volvulus 0.0022 0.015 0.0141
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.015 0.0156
Echinococcus granulosus microtubule associated protein 2 0.0667 0.9626 1
Onchocerca volvulus 0.0022 0.015 0.0141
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0191 0.119
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0051 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.015 0.0156
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0413 0.0429
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0255 0.3581 0.372
Toxoplasma gondii sugar transporter ST3 0.0015 0.0051 0.0131
Mycobacterium ulcerans electron transfer protein FdxB 0.0022 0.016 0.0167
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.189 0.1902
Echinococcus multilocularis pikachurin 0.005 0.0562 0.0584
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0234 0.3266 0.7025
Onchocerca volvulus 0.0027 0.0229 0.024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.015 0.0156
Brugia malayi hypothetical protein 0.0022 0.015 0.0151
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.013 0.1737 0.2161
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0095 0.1226 0.1274
Brugia malayi Nuclear hormone receptor family member nhr-19 0.046 0.6596 0.6638
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0849 1
Echinococcus multilocularis tubulin alpha 3 chain 0.0017 0.0087 0.009
Onchocerca volvulus 0.0022 0.015 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.015 0.0156
Brugia malayi Sugar transporter family protein 0.0015 0.0051 0.0052
Schistosoma mansoni amine GPCR 0.0022 0.015 0.0156
Onchocerca volvulus 0.0015 0.0051 0.0017
Schistosoma mansoni biogenic amine receptor 0.0022 0.015 0.0156
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.015 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0043 0.0458 0.0624
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.046 0.6596 0.8207
Mycobacterium tuberculosis Probable oxidoreductase 0.0022 0.016 0.0238
Schistosoma mansoni zinc finger protein 0.0217 0.3024 0.3141
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.015 0.0186
Brugia malayi Sulfotransferase domain containing protein 0.0021 0.0137 0.0138
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Brugia malayi Cytochrome P450 family protein 0.0069 0.0849 0.0854
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.015 0.0156
Brugia malayi hypothetical protein 0.0688 0.9936 1
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.015 0.0156
Brugia malayi Tubulin alpha-2 chain 0.0017 0.0087 0.0087
Loa Loa (eye worm) sulfotransferase domain-containing protein 0.0021 0.0137 0.0171
Loa Loa (eye worm) hypothetical protein 0.0095 0.1226 0.1525
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0022 0.016 0.0167
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0043 0.0458 0.5098
Loa Loa (eye worm) tubulin alpha-3 chain 0.0012 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0022 0.016 0.0167
Onchocerca volvulus 0.0015 0.0051 0.0017
Trichomonas vaginalis tubulin beta chain, putative 0.0017 0.0087 0.0077
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0043 0.0458 0.0624
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0095 0.1226 1
Schistosoma mansoni cpg binding protein 0.0029 0.0264 0.0274
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0229 0.0238
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0043 0.0458 0.0889
Leishmania major ferredoxin, 2fe-2s-like protein 0.0022 0.016 0.1366
Brugia malayi hypothetical protein 0.0041 0.0431 0.0433
Echinococcus multilocularis neuropeptide receptor 0.0022 0.015 0.0156
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.015 0.0156
Loa Loa (eye worm) agrin synaptic family protein 0.0018 0.0104 0.0129
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Loa Loa (eye worm) tubulin alpha chain 0.0017 0.0087 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0194 0.0185
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.046 0.6596 0.6852
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Mycobacterium ulcerans hydrolase 0.0025 0.0205 0.0236
Onchocerca volvulus 0.0021 0.0137 0.0125
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0043 0.0458 0.0624
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0095 0.1226 0.1274
Echinococcus granulosus tubulin alpha chain 0.0017 0.0087 0.009
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.01 0.1456
Echinococcus granulosus intermediate filament protein 0.0052 0.0603 0.0626
Brugia malayi Nuclear hormone receptor family member nhr-14 0.046 0.6596 0.6638
Schistosoma mansoni alpha tubulin 0.0017 0.0087 0.009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0051 0.0064
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0205 0.2847 0.429
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0078 0.0982 0.1221
Loa Loa (eye worm) sulfotransferase domain-containing protein 0.0021 0.0137 0.0171
Toxoplasma gondii sugar transporter ST2 0.0015 0.0051 0.0131
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0025 0.0205 0.0196
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0431 0.0447
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.015 0.0141
Loa Loa (eye worm) hypothetical protein 0.0559 0.8038 1
Echinococcus multilocularis fmrfamide receptor 0.0022 0.015 0.0156
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Mycobacterium tuberculosis Glycolipid sulfotransferase 0.0021 0.0137 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.01 0.0614
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.015 0.0156
Brugia malayi TAR-binding protein 0.013 0.1737 0.1748
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0018 0.0104 0.0104
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0194 0.179
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.5638 0.5857
Brugia malayi Nuclear hormone receptor-like 1 0.046 0.6596 0.6638
Loa Loa (eye worm) tubulin alpha 2 0.0013 0.0027 0.0034
Onchocerca volvulus 0.0018 0.0104 0.0083
Echinococcus multilocularis tubulin alpha 1C chain 0.0017 0.0087 0.009
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0194 0.0202
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.015 0.0186
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.015 0.0151
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0431 0.0536
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0015 0.0051 0.0053
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0191 0.1753
Onchocerca volvulus 0.0015 0.0051 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0047
Echinococcus granulosus Nuclear hormone receptor HR96 0.0217 0.3024 0.3141
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0266 0.0276
Brugia malayi laminin-like protein K08C7.3 precursor 0.005 0.0562 0.0565
Echinococcus granulosus Tubulin alpha 1 chain 0.0017 0.0087 0.009
Onchocerca volvulus 0.0095 0.1226 0.1486
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.01 0.4497
Mycobacterium ulcerans putative regulatory protein 0.007 0.0861 0.1242
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.015 0.0156
Trichomonas vaginalis Ferredoxin 3 0.0022 0.016 0.0151
Schistosoma mansoni ap endonuclease 0.0018 0.01 0.0104
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0043 0.0458 0.0889
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0043 0.0458 0.0889
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.015 0.0156
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0043 0.0458 0.0889
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.1528 0.1901
Onchocerca volvulus 0.0022 0.015 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-19 0.046 0.6596 0.6638
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.015 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-1 0.046 0.6596 0.6638
Loa Loa (eye worm) sulfotransferase domain-containing protein 0.0021 0.0137 0.0171
Loa Loa (eye worm) nuclear hormone receptor 0.0217 0.3024 0.3762
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.189 0.1964
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.046 0.6596 0.6852
Brugia malayi Doublecortin family protein 0.0041 0.0431 0.0433
Onchocerca volvulus 0.0027 0.0229 0.024
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus cytochrome P450 2K1 0.0043 0.0458 0.0476
Plasmodium falciparum transporter, putative 0.0095 0.1226 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Brugia malayi Cytochrome P450 family protein 0.0158 0.2158 0.2172
Echinococcus multilocularis transfer RNA-Lys 0.007 0.0861 0.0894
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0022 0.016 0.0161
Echinococcus multilocularis thyroid hormone receptor alpha 0.0582 0.8383 0.8708
Brugia malayi Sulfatase family protein 0.0025 0.0205 0.0207
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0234 0.3266 0.4933
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0022 0.016 0.0161
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0051 0.0053
Echinococcus multilocularis bifunctional heparan sulfate 0.0021 0.0137 0.0143
Mycobacterium leprae putative cytochrome p450 0.0043 0.0458 1
Echinococcus granulosus tubulin alpha 3 chain 0.0017 0.0087 0.009
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0518 0.0521
Echinococcus multilocularis g protein coupled receptor 0.0022 0.015 0.0156
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0043 0.0458 0.5098
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.015 0.0186
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0051 0.0053
Schistosoma mansoni lamin 0.0052 0.0603 0.0626
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0051 0.0042
Echinococcus granulosus tar DNA binding protein 0.013 0.1737 0.1804
Brugia malayi hypothetical protein 0.0317 0.4489 0.4518
Loa Loa (eye worm) hypothetical protein 0.0013 0.0027 0.0034
Schistosoma mansoni steroid hormone receptor ad4bp 0.046 0.6596 0.6852
Loa Loa (eye worm) hypothetical protein 0.0217 0.3024 0.3762
Schistosoma mansoni laminin gamma-3 chain 0.005 0.0562 0.0584
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.01 0.0614
Echinococcus granulosus bifunctional heparan sulfate 0.0021 0.0137 0.0143
Leishmania major alpha tubulin 0.0017 0.0087 0.0443
Loa Loa (eye worm) hypothetical protein 0.0029 0.0266 0.0331
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0051 0.0042
Treponema pallidum hypothetical protein 0.0113 0.1486 0.1746
Schistosoma mansoni sugar transporter 0.0015 0.0051 0.0053
Brugia malayi nuclear receptor RXR 0.0217 0.3024 0.3043
Brugia malayi conserved hypotetical protein 0.0217 0.3024 0.3043
Loa Loa (eye worm) hypothetical protein 0.0022 0.015 0.0186
Onchocerca volvulus 0.0022 0.015 0.0141
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0095 0.1226 0.1274

Activities

Activity type Activity value Assay description Source Reference
HACU improvement (functional) = 8 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-7 M. ChEMBL. No reference
HACU improvement (functional) = 8 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-7 M. ChEMBL. No reference
HACU improvement (functional) = 18 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-6 M. ChEMBL. No reference
HACU improvement (functional) = 18 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-6 M. ChEMBL. No reference
HACU improvement (functional) = 21 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-5 M. ChEMBL. No reference
HACU improvement (functional) = 21 % Effect on uptake amount of [3H]-choline in the hippocampal synaptosomes of AF64A-treated rats at a concentration of 10e-5 M. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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