Detailed information for compound 564481

Basic information

Technical information
  • TDR Targets ID: 564481
  • Name: 2-cyanoguanidine
  • MW: 84.08 | Formula: C2H4N4
  • H donors: 2 H acceptors: 1 LogP: -0.89 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=N)NC#N
  • InChi: 1S/C2H4N4/c3-1-6-2(4)5/h(H4,4,5,6)
  • InChiKey: QGBSISYHAICWAH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • dicyandiamido
  • 125148-58-5
  • 461-58-5
  • 139351-77-2
  • 139351-78-3
  • 157480-33-6
  • AIDS-103486
  • AIDS103486
  • Dicyanadiamide
  • 36600_FLUKA
  • ST5409136
  • 1-Cyanoguanidine
  • Cyanoguanidine
  • Dicyandiamide
  • Dicyanodiamide
  • Guanidine, cyano-
  • N-Cyanoguanidine
  • NSC2031
  • Pyroset DO
  • InChI=1/C2H4N4/c3-1-6-2(4)5/h(H4,4,5,6
  • D76609_ALDRICH
  • ACR-H 3636
  • AI3-14632
  • Araldite HT 986
  • Araldite XB 2879B
  • Araldite XB 2979B
  • Bakelite VE 2560
  • CCRIS 3478
  • Dicyandiamin [German]
  • EINECS 207-312-8
  • Epicure DICY 15
  • Epicure DICY 7
  • HSDB 2126
  • NSC 2031
  • XB 2879B

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0204
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0043 0.0106
Echinococcus granulosus JmjC domain containing protein 4 0.001 0.0012 0.003
Onchocerca volvulus 0.0464 0.2037 0.5022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0022 0.02
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Schistosoma mansoni nAChR subunit 0.0464 0.2037 0.2037
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0092 0.024
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0188 0.049
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0008 0.0001 0.0003
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0107 0.0264
Brugia malayi Cytochrome P450 family protein 0.0022 0.0066 0.0163
Echinococcus granulosus endonuclease exonuclease phosphatase 0.006 0.0235 0.0579
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0139 0.0344
Schistosoma mansoni Smad4 0.0008 0.0003 0.0003
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0003 0.0008
Brugia malayi hypothetical protein 0.0075 0.03 0.074
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Entamoeba histolytica phosphofructokinase, putative 0.0033 0.0115 0.1061
Echinococcus granulosus expressed protein 0.0192 0.0821 0.2024
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Mycobacterium tuberculosis Probable lipase LipD 0.0011 0.0016 0.0179
Schistosoma mansoni phd/f-box containing protein 0.001 0.0012 0.0012
Echinococcus multilocularis neuroligin 0.0026 0.0083 0.0204
Loa Loa (eye worm) hypothetical protein 0.025 0.1082 0.2667
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0464 0.2037 0.2037
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0464 0.2037 0.5022
Leishmania major pyruvate kinase 0.0032 0.0111 0.0291
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0107 0.3269
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0013 0.0026 0.0064
Loa Loa (eye worm) MBCTL1 0.0017 0.0041 0.01
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0008 0.0001 0.0098
Onchocerca volvulus 0.0011 0.0016 0.0039
Brugia malayi Cation transporter family protein 0.0464 0.2037 0.5022
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.006 0.0235 0.0579
Brugia malayi hypothetical protein 0.001 0.0011 0.0026
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0013 0.0026 0.0068
Onchocerca volvulus 0.0214 0.0922 0.2272
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0033 0.0115 0.13
Echinococcus multilocularis lamin b receptor 0.0025 0.0079 0.0196
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0111 0.3398
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0204
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0215 0.0928 0.2288
Brugia malayi glutathione reductase 0.0081 0.0328 0.0809
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0008 0.0001 0.0013
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0464 0.2037 0.5022
Schistosoma mansoni sex comb on midleg homolog 0.0015 0.0032 0.0032
Echinococcus granulosus para nitrobenzyl esterase 0.0026 0.0083 0.0204
Echinococcus granulosus neuroligin 0.0026 0.0083 0.0204
Loa Loa (eye worm) hypothetical protein 0.025 0.1082 0.2667
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0464 0.2037 0.5022
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0017 0.0041 0.01
Echinococcus granulosus beta LACTamase domain containing family member 0.0011 0.0016 0.0039
Plasmodium falciparum phd finger protein, putative 0.0032 0.0107 0.3269
Loa Loa (eye worm) ACC-1 protein 0.0464 0.2037 0.5022
Brugia malayi Carboxylesterase family protein 0.0026 0.0083 0.0204
Schistosoma mansoni nAChR subunit 0.0214 0.0922 0.0922
Echinococcus multilocularis phd:f box containing protein 0.001 0.0012 0.003
Mycobacterium leprae putative cytochrome p450 0.0008 0.0001 0.0013
Echinococcus multilocularis pyruvate kinase 0.0032 0.0111 0.0275
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0092 0.024
Loa Loa (eye worm) hypothetical protein 0.0163 0.0693 0.1708
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Onchocerca volvulus 0.0026 0.0083 0.0204
Schistosoma mansoni pyruvate kinase 0.0032 0.0111 0.0111
Loa Loa (eye worm) CYP4Cod1 0.0022 0.0066 0.0163
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.001 0.0011 0.0026
Onchocerca volvulus 0.0214 0.0922 0.2272
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0185 0.0791 0.8958
Schistosoma mansoni lamin 0.0011 0.0015 0.0015
Loa Loa (eye worm) beta-lactamase 0.0011 0.0016 0.0039
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0464 0.2037 0.2037
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.025 0.1082 0.2667
Brugia malayi excitatory GABA receptor EXP-1A 0.0464 0.2037 0.5022
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0214 0.0922 0.2272
Trypanosoma brucei protein kinase, putative 0.005 0.0188 0.049
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0134 0.033
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0026 0.0083 0.0083
Entamoeba histolytica hypothetical protein 0.001 0.0011 0.0098
Leishmania major phosphatidylinositol 3-kinase, putative 0.0008 0.0001 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0111 0.0111
Loa Loa (eye worm) glutathione reductase 0.0081 0.0328 0.0809
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0011 0.0026
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0013 0.0026 0.0793
Echinococcus granulosus lamin dm0 0.0011 0.0015 0.0037
Onchocerca volvulus 0.0011 0.0016 0.0039
Echinococcus multilocularis JmjC domain containing protein 4 0.001 0.0012 0.003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0023 0.007 0.0172
Echinococcus multilocularis glycine receptor subunit beta 0.0464 0.2037 0.5022
Brugia malayi MH2 domain containing protein 0.0008 0.0003 0.0008
Echinococcus granulosus Smad4 0.0008 0.0003 0.0008
Mycobacterium ulcerans hypothetical protein 0.0011 0.0016 0.1375
Brugia malayi MH2 domain containing protein 0.0008 0.0003 0.0008
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0043 0.0112
Echinococcus granulosus intermediate filament protein 0.0011 0.0015 0.0037
Onchocerca volvulus 0.0026 0.0083 0.0204
Mycobacterium leprae Probable lipase LipE 0.0011 0.0016 0.0179
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0001 0.0003
Schistosoma mansoni intermediate filament proteins 0.0011 0.0015 0.0015
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0464 0.2037 0.5022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0028 0.0255
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0011 0.0016 0.0179
Echinococcus multilocularis pyruvate kinase 0.0017 0.0041 0.0101
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0013 0.0033
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0107 0.0264
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0014 0.0028 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0043 0.039
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0026 0.0083 0.0937
Plasmodium vivax thioredoxin reductase, putative 0.0081 0.0328 1
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.001 0.0012 0.0369
Trichomonas vaginalis set domain proteins, putative 0.0256 0.1108 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0464 0.2037 0.5022
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.001 0.0011 0.0026
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0464 0.2037 0.5022
Loa Loa (eye worm) acetyltransferase 0.0045 0.0167 0.0413
Echinococcus multilocularis regulator of G protein signaling 3 0.001 0.0011 0.0026
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0092 0.024
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0214 0.0922 0.2272
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0111 0.0291
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0464 0.2037 0.5022
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0008 0.0001 0.0098
Echinococcus multilocularis lysine specific demethylase 6a 0.001 0.0012 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0018 0.0018
Onchocerca volvulus 0.0052 0.0199 0.0491
Trypanosoma brucei MATE efflux family protein, putative 0.0016 0.0037 0.0096
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0409 0.1791 0.1791
Mycobacterium leprae Conserved hypothetical protein 0.0008 0.0001 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0115 0.1035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Plasmodium falciparum histone acetyltransferase GCN5 0.0012 0.002 0.0608
Toxoplasma gondii target of rapamycin (TOR), putative 0.0017 0.0043 0.1318
Echinococcus multilocularis 0.0008 0.0001 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0092 0.024
Echinococcus multilocularis thioredoxin glutathione reductase 0.0081 0.0329 0.0811
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.1106 0.2728
Echinococcus granulosus glycine receptor subunit alpha 1 0.0464 0.2037 0.5022
Brugia malayi Cytochrome P450 family protein 0.0008 0.0001 0.0003
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0214 0.0922 0.2272
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.025 0.1082 0.2667
Leishmania major hypothetical protein, conserved 0.0016 0.0037 0.0096
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0017 0.0041 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0043 0.039
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0008 0.0001 0.0098
Brugia malayi hypothetical protein 0.0214 0.0922 0.2272
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.1106 0.2728
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0464 0.2037 0.5022
Schistosoma mansoni hypothetical protein 0.0008 0.0001 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0008 0.0001 0.0013
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0033 0.0115 0.0299
Entamoeba histolytica hypothetical protein 0.025 0.1082 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0107 0.3269
Brugia malayi Carboxylesterase family protein 0.0154 0.0653 0.1611
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0028 0.0092 0.0227
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.007 0.0628
Brugia malayi Cation transporter family protein 0.0464 0.2037 0.5022
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0068 0.0167
Brugia malayi beta-lactamase 0.0011 0.0016 0.0039
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0022 0.0066 0.5764
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0008 0.0001 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0043 0.039
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0139 0.0344
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0464 0.2037 0.5022
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0028 0.0092 0.0227
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0008 0.0001 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0032 0.011 0.011
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0049 0.0127
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0028 0.0092 0.1042
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0008 0.0001 0.0013
Echinococcus granulosus histone acetyltransferase KAT2B 0.0014 0.0028 0.0069
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0214 0.0922 0.2272
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0188 0.0463
Mycobacterium tuberculosis Probable oxidoreductase 0.0205 0.0883 1
Brugia malayi MH2 domain containing protein 0.0119 0.0499 0.1232
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0214 0.0922 0.2272
Plasmodium vivax hypothetical protein, conserved 0.001 0.0013 0.0387
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0014 0.0031 0.0076
Echinococcus multilocularis regulator of G protein signaling 0.001 0.0011 0.0026
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0009 0.0007 0.0206
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0043 0.1307
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0037 0.0096
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0204
Onchocerca volvulus 0.0032 0.0111 0.0273
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0008 0.0001 0.0098
Plasmodium vivax pyruvate kinase, putative 0.0032 0.0111 0.3398
Loa Loa (eye worm) cytochrome P450 0.0008 0.0001 0.0003
Onchocerca volvulus 0.025 0.1082 0.2667
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0111 0.0291
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0016 0.0041
Loa Loa (eye worm) hypothetical protein 0.0022 0.0063 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0001 0.0011
Echinococcus granulosus pyruvate kinase 0.0032 0.0111 0.0275
Echinococcus granulosus nAChR subunit 0.025 0.1082 0.2667
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0115 0.1035
Echinococcus granulosus carboxylesterase 5A 0.0154 0.0653 0.1611
Brugia malayi jmjC domain containing protein 0.001 0.0012 0.003
Onchocerca volvulus 0.0026 0.0083 0.0204
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0026 0.0083 0.0204
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0028 0.0092 0.024
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0111 0.0275
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0917 0.4056 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0092 0.024
Echinococcus multilocularis axis inhibition protein axin 0.001 0.0011 0.0026
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0013 0.0026 0.0068
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0369 0.0909
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0369 0.0909
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0003 0.0008
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0028 0.0092 0.2803
Brugia malayi mbt repeat family protein 0.0015 0.0032 0.0078
Schistosoma mansoni smad1 5 8 and 0.0008 0.0003 0.0003
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0026 0.0083 0.0204
Trypanosoma cruzi sterol C-24 reductase, putative 0.0025 0.0079 0.0207
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0464 0.2037 0.5022
Schistosoma mansoni myelin transcription factor 1 myt1 0.0017 0.0041 0.0041
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.001 0.0011 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0188 0.0188
Echinococcus granulosus glycine receptor subunit alpha 1 0.0464 0.2037 0.5022
Echinococcus granulosus thioredoxin glutathione reductase 0.0081 0.0329 0.0811
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0026 0.0083 0.0083
Mycobacterium ulcerans 6-phosphofructokinase 0.0033 0.0115 1
Loa Loa (eye worm) hypothetical protein 0.0868 0.3836 0.9458
Loa Loa (eye worm) ACC-1 protein 0.0464 0.2037 0.5022
Schistosoma mansoni 6-phosphofructokinase 0.0033 0.0115 0.0115
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0464 0.2037 0.5022
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0008 0.0001 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0049 0.0438
Brugia malayi Pyruvate kinase, M2 isozyme 0.0032 0.0111 0.0275
Onchocerca volvulus 0.0032 0.011 0.027
Mycobacterium ulcerans beta-lactamase 0.0011 0.0016 0.1375
Brugia malayi Bromodomain containing protein 0.0024 0.0074 0.0182
Schistosoma mansoni hypothetical protein 0.0068 0.027 0.027
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0214 0.0922 0.2272
Loa Loa (eye worm) carboxylesterase 0.0026 0.0083 0.0204
Chlamydia trachomatis pyruvate kinase 0.0032 0.0111 1
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0868 0.3836 1
Loa Loa (eye worm) hypothetical protein 0.0161 0.0687 0.1693
Echinococcus multilocularis peregrin 0.0033 0.0115 0.0284
Loa Loa (eye worm) thioredoxin reductase 0.0081 0.0328 0.0809
Brugia malayi Regulator of G protein signaling domain containing protein 0.001 0.0011 0.0026
Echinococcus multilocularis 6 phosphofructokinase 0.0033 0.0115 0.0283
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0464 0.2037 0.5022
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0026 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0068 0.027 0.027
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0008 0.0001 0.0013
Trypanosoma brucei cytochrome P450, putative 0.0022 0.0066 0.0172
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0023 0.007 0.0172
Schistosoma mansoni vesicular acetylcholine transporter 0.0917 0.4056 0.4056
Brugia malayi Bromodomain containing protein 0.0033 0.0115 0.0284
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0185 0.0791 0.8958
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0011 0.0016 0.1375
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.001 0.0013 0.0387
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0008 0.0001 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0013 0.0013
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0001 0.0003
Trichomonas vaginalis mercuric reductase, putative 0.0028 0.0092 0.083
Mycobacterium leprae Probable pyruvate kinase PykA 0.0032 0.0111 0.1263
Brugia malayi Carboxylesterase family protein 0.0026 0.0083 0.0204
Echinococcus multilocularis jumonji domain containing 1A 0.001 0.0012 0.003
Trypanosoma brucei membrane transporter protein, putative 0.0016 0.0037 0.0096
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0464 0.2037 0.5022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0369 0.0369
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0092 0.024
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Schistosoma mansoni pyruvate kinase 0.0017 0.0041 0.0041
Mycobacterium ulcerans esterase/lipase LipP 0.0011 0.0016 0.1375
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0055 0.0492
Echinococcus granulosus nAChR subunit 0.0464 0.2037 0.5022
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.001 0.0011 0.0096
Loa Loa (eye worm) hypothetical protein 0.001 0.0011 0.0026
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0205 0.0883 1
Echinococcus multilocularis muscleblind protein 1 0.0161 0.0687 0.1693
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.03 0.074
Loa Loa (eye worm) acetylcholine receptor protein 0.0214 0.0922 0.2272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0049 0.0438
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0008 0.0001 0.0013
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0021 0.0051
Schistosoma mansoni survival motor neuron protein 0.0052 0.0199 0.0199
Schistosoma mansoni neurotransmitter gated ion channel 0.0214 0.0922 0.0922
Echinococcus multilocularis nAChR subunit 0.025 0.1082 0.2667
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0028 0.0092 0.2803
Loa Loa (eye worm) hypothetical protein 0.0161 0.0687 0.1693
Echinococcus multilocularis Regulator of G protein signaling 20 0.001 0.0011 0.0026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0369 0.0909
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0011 0.0015 0.004
Echinococcus multilocularis beta adrenergic receptor kinase 0.001 0.0013 0.0031
Echinococcus granulosus pyruvate kinase 0.0017 0.0041 0.0101
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0016 0.0037 0.0091
Brugia malayi Regulator of G protein signaling domain containing protein 0.001 0.0011 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0009 0.0007 0.0061
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0012 0.003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0107 0.0264
Mycobacterium ulcerans pyruvate kinase 0.0032 0.0111 0.9716
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0043 0.0112
Loa Loa (eye worm) 6-phosphofructokinase 0.0033 0.0115 0.0283
Loa Loa (eye worm) hypothetical protein 0.025 0.1082 0.2667
Echinococcus granulosus lysine specific demethylase 6a 0.001 0.0012 0.003
Giardia lamblia DNA repair protein RAD52 0.0139 0.0589 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0009 0.0007 0.0206
Onchocerca volvulus 0.0214 0.0922 0.2272
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0008 0.0001 0.0098
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0013 0.0026 0.2829
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0009 0.0007 0.0062
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0154 0.0653 0.0653
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0011 0.0015 0.0037
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0003 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0037 0.0096
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0008 0.0001 0.0098
Echinococcus granulosus geminin 0.0068 0.027 0.0666
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0066 0.0172
Entamoeba histolytica hypothetical protein 0.0075 0.03 0.2775
Echinococcus multilocularis MAM 0.0032 0.011 0.027
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0011 0.0016 0.0039
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0068 0.0626
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0464 0.2037 0.5022
Echinococcus granulosus vesicular acetylcholine transporter 0.0917 0.4056 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0013 0.0026 0.2268
Trichomonas vaginalis phosphofructokinase, putative 0.0009 0.0007 0.0061
Brugia malayi jmjC domain containing protein 0.0103 0.0427 0.1053
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0028 0.0092 0.2803
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.03 0.074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0022 0.02
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0092 0.024
Schistosoma mansoni sex comb on midleg homolog 0.0015 0.0032 0.0032
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0014 0.0028 0.0854
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0023 0.007 0.0181
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0107 0.0264
Loa Loa (eye worm) hypothetical protein 0.0012 0.0019 0.0047
Echinococcus granulosus peregrin 0.0033 0.0115 0.0284
Loa Loa (eye worm) hypothetical protein 0.0049 0.0187 0.046
Giardia lamblia Pyruvate kinase 0.0017 0.0041 0.0697
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0464 0.2037 0.5022
Schistosoma mansoni regulator of G protein signaling 0.001 0.0011 0.0011
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0011 0.0026
Schistosoma mansoni axis inhibition protein axin 0.001 0.0011 0.0011
Onchocerca volvulus Alhambra homolog 0.0032 0.0107 0.0264
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0043 0.039
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.003
Leishmania major hypothetical protein, conserved 0.001 0.0012 0.0032
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0464 0.2037 0.5022
Brugia malayi 6-phosphofructokinase 0.0033 0.0115 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0001 0.0011
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0008 0.0001 0.0098
Echinococcus multilocularis pyruvate kinase 0.0026 0.0081 0.02
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0039
Toxoplasma gondii NADPH-glutathione reductase 0.0028 0.0092 0.2803
Brugia malayi hypothetical protein 0.0214 0.0922 0.2272
Trypanosoma brucei hypothetical protein, conserved 0.0011 0.0016 0.0041
Loa Loa (eye worm) acetylcholinesterase 1 0.0154 0.0653 0.1611
Onchocerca volvulus 0.0026 0.0083 0.0204
Trypanosoma brucei C-14 sterol reductase, putative 0.0025 0.0079 0.0207
Loa Loa (eye worm) hypothetical protein 0.025 0.1082 0.2667
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0008 0.0001 0.0003
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0868 0.3836 0.9458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0049 0.0438
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0111 0.3371
Loa Loa (eye worm) hypothetical protein 0.0154 0.0653 0.1611
Echinococcus granulosus regulator of G protein signaling 3 0.001 0.0011 0.0026
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0092 1
Echinococcus granulosus BC026374 protein S09 family 0.0026 0.0083 0.0204
Leishmania major C-14 sterol reductase, putative 0.0025 0.0079 0.0207
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0464 0.2037 0.5022
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0043 0.0106
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0111 0.0273
Echinococcus multilocularis smad 0.0008 0.0003 0.0008
Entamoeba histolytica acetyltransferase, GNAT family 0.0012 0.002 0.0184
Trypanosoma cruzi trypanothione reductase, putative 0.0028 0.0092 0.024
Onchocerca volvulus 0.0464 0.2037 0.5022
Brugia malayi PHD-finger family protein 0.0009 0.0006 0.0014
Brugia malayi Pre-SET motif family protein 0.0032 0.0111 0.0273
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0008 0.0001 0.0003
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0008 0.0001 0.0098
Brugia malayi jmjC domain containing protein 0.001 0.0012 0.003
Schistosoma mansoni acetylcholine receptor-related 0.0214 0.0922 0.0922
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0009 0.0007 0.0588
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0008 0.0001 0.0098
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0225 0.097 0.2391
Loa Loa (eye worm) hypothetical protein 0.001 0.0011 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0204
Onchocerca volvulus 0.0464 0.2037 0.5022
Treponema pallidum NADH oxidase 0.0028 0.0092 0.8015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0039
Loa Loa (eye worm) hypothetical protein 0.025 0.1082 0.2667
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0188 0.0463
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0022 0.02
Entamoeba histolytica hypothetical protein 0.0075 0.03 0.2775
Brugia malayi PHD-finger family protein 0.0032 0.0107 0.0264
Brugia malayi acetyltransferase, GNAT family protein 0.0045 0.0167 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0022 0.0201
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0037 0.0096
Echinococcus granulosus lamin 0.0011 0.0015 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0011 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0065 0.016
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0443 0.1944 0.4794
Loa Loa (eye worm) hypothetical protein 0.0055 0.0212 0.0522
Leishmania major hypothetical protein, conserved 0.0016 0.0037 0.0096
Trypanosoma brucei membrane transporter protein, putative 0.0016 0.0037 0.0096
Brugia malayi Pyruvate kinase, muscle isozyme 0.0032 0.0111 0.0275
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0214 0.0922 0.2272
Brugia malayi Cytochrome P450 family protein 0.0017 0.0045 0.011
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0013 0.0026 0.0064
Trichomonas vaginalis penicillin-binding protein, putative 0.0011 0.0016 0.0142
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0008 0.0001 0.0003
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0008 0.0001 0.0098
Schistosoma mansoni hypothetical protein 0.0032 0.0107 0.0107
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0464 0.2037 0.5022
Schistosoma mansoni nAChR subunit 0.0464 0.2037 0.2037
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Schistosoma mansoni smad1 5 8 and 0.0008 0.0003 0.0003
Echinococcus granulosus pyruvate kinase 0.0017 0.0041 0.0101
Leishmania major cytochrome p450-like protein 0.0008 0.0001 0.0003
Onchocerca volvulus 0.025 0.1082 0.2667
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0464 0.2037 0.5022
Brugia malayi hypothetical protein 0.0026 0.0083 0.0204
Echinococcus granulosus acetylcholinesterase 0.0154 0.0653 0.1611
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0009 0.0007 0.0605
Leishmania major C-8 sterol isomerase-like protein 0.0868 0.3836 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0015 0.0032 0.0078
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0008 0.0001 0.0098
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0014 0.0028 0.0854
Brugia malayi cytochrome P450 0.0008 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0204
Echinococcus granulosus phd:f box containing protein 0.001 0.0012 0.003
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0008 0.0001 0.0098
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0023 0.007 0.0172
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0067
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0013 0.0026 0.0295
Leishmania major cytochrome p450-like protein 0.0008 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0037
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0028 0.0092 0.8015
Trypanosoma cruzi membrane transporter protein, putative 0.0016 0.0037 0.0096
Mycobacterium tuberculosis Conserved protein 0.0011 0.0016 0.0179
Trypanosoma brucei C-8 sterol isomerase, putative 0.0868 0.3836 1
Loa Loa (eye worm) hypothetical protein 0.0246 0.1063 0.2622
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.001 0.0013 0.0031
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0185 0.0791 0.8958
Echinococcus granulosus small conductance calcium activated potassium 0.0132 0.0554 0.1365
Onchocerca volvulus 0.0464 0.2037 0.5022
Entamoeba histolytica hypothetical protein 0.0075 0.03 0.2775
Schistosoma mansoni cytochrome P450 0.0008 0.0001 0.0001
Echinococcus granulosus lamin b receptor 0.0025 0.0079 0.0196
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0043 0.0106
Brugia malayi exodeoxyribonuclease III family protein 0.0013 0.0026 0.0064
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0008 0.0001 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0011 0.0016 0.0142
Loa Loa (eye worm) hypothetical protein 0.0132 0.0554 0.1365
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0464 0.2037 0.2037
Echinococcus granulosus tm gpcr rhodopsin 0.0215 0.0928 0.2288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0028 0.0255
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0011 0.0016 0.0016
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0028 0.0092 0.2803
Toxoplasma gondii thioredoxin reductase 0.0081 0.0328 1
Trypanosoma brucei trypanothione reductase 0.0081 0.0328 0.0855
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.025 0.1082 0.2667
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0464 0.2037 0.5022
Brugia malayi Muscleblind-like protein 0.0161 0.0687 0.1693
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0008 0.0001 0.0098
Brugia malayi mbt repeat family protein 0.0015 0.0032 0.0078
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0003 0.0008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0009 0.0007 0.0206
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.001 0.0013 0.0031
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0021 0.0059 0.0145
Schistosoma mansoni hypothetical protein 0.0029 0.0095 0.0095
Brugia malayi hypothetical protein 0.001 0.0011 0.0026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0214 0.0922 0.2272
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.025 0.1082 0.1082
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0043 0.1307
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0107 0.0107
Onchocerca volvulus 0.0026 0.0083 0.0204
Loa Loa (eye worm) hypothetical protein 0.025 0.1082 0.2667
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0185 0.0791 0.8958
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0115 0.1035
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0214 0.0922 0.2272
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0092 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0139 0.0139
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0008 0.0001 0.0098
Mycobacterium tuberculosis Probable lipase LipE 0.0011 0.0016 0.0179
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0049 0.0438
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0019 0.0053 0.013
Mycobacterium tuberculosis Conserved protein 0.0011 0.0016 0.0179
Schistosoma mansoni hypothetical protein 0.0052 0.0199 0.0199
Onchocerca volvulus 0.0464 0.2037 0.5022
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0008 0.0001 0.0098
Echinococcus granulosus jumonji domain containing 1A 0.001 0.0012 0.003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0011 0.0016 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0115 0.1035
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0028 0.0092 0.0092
Loa Loa (eye worm) carboxylesterase 0.0026 0.0083 0.0204
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0008 0.0001 0.0098
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0188 0.049
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0139 0.0589 0.5443
Brugia malayi Smad1 0.0008 0.0003 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0013 0.0013
Echinococcus granulosus pyruvate kinase 0.0032 0.0111 0.0275
Plasmodium falciparum JmjC domain-containing protein, putative 0.001 0.0012 0.0369
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0035
Plasmodium falciparum pyruvate kinase 0.0032 0.0111 0.3398
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0105 0.026
Schistosoma mansoni regulator of G protein signaling 0.001 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0235 0.1016 0.2506
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0464 0.2037 0.5022
Mycobacterium tuberculosis Probable esterase LipL 0.0011 0.0016 0.0179
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.027
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0028 0.0092 0.8015
Brugia malayi Cytochrome P450 family protein 0.0022 0.0066 0.0163
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.001 0.0011 0.0026
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.001 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Trypanosoma brucei membrane transporter protein, putative 0.0016 0.0037 0.0096
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0037 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0022 0.0201
Schistosoma mansoni ap endonuclease 0.0013 0.0026 0.0026
Brugia malayi regulator of G-protein signaling rgs-7 0.001 0.0011 0.0026
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0185 0.0791 0.8958
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0464 0.2037 0.5022
Entamoeba histolytica phosphofructokinase, putative 0.0033 0.0115 0.1061
Toxoplasma gondii ABC1 family protein 0.0011 0.0016 0.0481
Echinococcus granulosus glycine receptor subunit alpha 1 0.0464 0.2037 0.5022
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0011 0.0096
Echinococcus multilocularis pyruvate kinase 0.0032 0.0111 0.0275
Echinococcus multilocularis muscleblind protein 0.0161 0.0687 0.1693
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0162 0.04
Schistosoma mansoni nAChR subunit 0.0464 0.2037 0.2037
Loa Loa (eye worm) hypothetical protein 0.025 0.1082 0.2667
Schistosoma mansoni nAChR subunit 0.0464 0.2037 0.2037
Brugia malayi Carboxylesterase family protein 0.0154 0.0653 0.1611
Mycobacterium tuberculosis Probable reductase 0.0185 0.0791 0.8958
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0001 0.0011
Schistosoma mansoni smad1 5 8 and 0.0008 0.0003 0.0003
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0205 0.0883 1
Echinococcus granulosus axis inhibition protein axin 0.001 0.0011 0.0026
Schistosoma mansoni Lamin B receptor (ERG24) 0.0025 0.0079 0.0079
Toxoplasma gondii exonuclease III APE 0.0013 0.0026 0.0793
Entamoeba histolytica hypothetical protein 0.001 0.0011 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0008 0.0001 0.0013
Toxoplasma gondii phosphofructokinase PFKII 0.0009 0.0007 0.0206
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0134 0.033
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0008 0.0001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0078
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0013 0.0026 0.0241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0043 0.039
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0033 0.0115 0.13
Schistosoma mansoni pyruvate kinase 0.0032 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.027
Brugia malayi MH1 domain containing protein 0.0008 0.0003 0.0008
Echinococcus granulosus glycine receptor subunit beta 0.0464 0.2037 0.5022
Leishmania major sterol C-24 reductase, putative 0.0025 0.0079 0.0207
Brugia malayi intermediate filament protein 0.0011 0.0015 0.0037
Schistosoma mansoni hypothetical protein 0.0132 0.0554 0.0554
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0014 0.0028 0.0854
Toxoplasma gondii cytochrome p450 superfamily protein 0.0008 0.0001 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0001 0.0011
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0049 0.0127
Schistosoma mansoni neuroligin 3 (S09 family) 0.0026 0.0083 0.0083
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0464 0.2037 0.5022
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Leishmania major pyruvate kinase 0.0032 0.0111 0.0291
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0033 0.0115 0.0299
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0159 0.0391
Brugia malayi hypothetical protein 0.0256 0.1106 0.2728
Brugia malayi hypothetical protein 0.0032 0.011 0.027
Loa Loa (eye worm) phosphofructokinase 0.0033 0.0115 0.0283
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0037 0.0096
Loa Loa (eye worm) hypothetical protein 0.0032 0.0111 0.0275
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0008 0.0001 0.0003
Echinococcus granulosus SAM and MBT domain containing protein 0.0015 0.0032 0.0078
Echinococcus multilocularis vesicular acetylcholine transporter 0.0917 0.4056 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0205 0.0883 1
Plasmodium vivax JmjC domain containing protein 0.001 0.0012 0.0369
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0026 0.0083 0.0937
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0012 0.003
Plasmodium falciparum thioredoxin reductase 0.0028 0.0092 0.2803
Schistosoma mansoni nAChR subunit 0.0214 0.0922 0.0922
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0008 0.0001 0.0098
Loa Loa (eye worm) TK/ALK protein kinase 0.0269 0.1165 0.2871
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0214 0.0922 0.2272
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0188 0.0463
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0043 0.0106
Giardia lamblia NADH oxidase lateral transfer candidate 0.0028 0.0092 0.1562
Echinococcus multilocularis glycine receptor subunit beta 0.0464 0.2037 0.5022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0092 0.024
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0009 0.0007 0.0061
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Echinococcus granulosus Regulator of G protein signaling 20 0.001 0.0011 0.0026
Brugia malayi jmjC domain containing protein 0.001 0.0012 0.003
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0011 0.0016 0.0039
Loa Loa (eye worm) PXA domain-containing protein 0.001 0.0011 0.0026
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0008 0.0001 0.0098
Brugia malayi isocitrate dehydrogenase 0.0017 0.0043 0.0106
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0043 0.1307
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0032 0.0111 0.1263
Loa Loa (eye worm) phosphatidylinositol 3 0.0023 0.007 0.0172
Echinococcus multilocularis pyruvate kinase 0.0017 0.0041 0.0101
Brugia malayi MH1 domain containing protein 0.0008 0.0003 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0011 0.0096
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0023 0.007 0.0181
Echinococcus multilocularis histone acetyltransferase MYST2 0.0017 0.0041 0.01
Onchocerca volvulus 0.0011 0.0016 0.0039
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0009 0.0007 0.0605
Mycobacterium tuberculosis Possible penicillin-binding protein 0.007 0.028 0.317
Brugia malayi PXA domain containing protein 0.001 0.0011 0.0026
Echinococcus multilocularis polycomb protein SCMH1 0.0015 0.0032 0.0078
Echinococcus multilocularis lamin dm0 0.0011 0.0015 0.0037
Echinococcus multilocularis expressed protein 0.0192 0.0821 0.2024
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Trichomonas vaginalis esterase, putative 0.0011 0.0016 0.0142
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0013 0.0387
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0008 0.0001 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0009 0.0007 0.0061
Echinococcus granulosus regulator of G protein signaling 3 0.001 0.0011 0.0026
Schistosoma mansoni calcium-activated potassium channel 0.0104 0.0432 0.0432
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0028 0.0092 0.0227
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0045 0.0167 0.0167
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0464 0.2037 0.5022
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Brugia malayi Carboxylesterase family protein 0.0026 0.0083 0.0204
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.025 0.1082 0.1082
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.001 0.0012 0.0032
Schistosoma mansoni multidrug resistance protein 0.0016 0.0037 0.0037
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0017 0.0041 0.01
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0464 0.2037 0.5022
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0092 0.024
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.001 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0036 0.0323
Trichomonas vaginalis D-aminoacylase, putative 0.0011 0.0016 0.0142
Loa Loa (eye worm) phosphatidylinositol 3 0.0008 0.0001 0.0003
Schistosoma mansoni nAChR subunit 0.0464 0.2037 0.2037
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Entamoeba histolytica phosphofructokinase, putative 0.0033 0.0115 0.1061
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.001 0.0011 0.0026
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0013 0.0033
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0464 0.2037 0.5022
Schistosoma mansoni calcium-activated potassium channel 0.0132 0.0554 0.0554
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0045 0.0167 0.0413
Echinococcus granulosus smad 0.0008 0.0003 0.0008
Leishmania major hypothetical protein, conserved 0.0011 0.0016 0.0041
Echinococcus granulosus acetylcholinesterase 0.0154 0.0653 0.1611
Schistosoma mansoni z-protein (S1r protein) 0.001 0.0011 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0013 0.0026 0.0068
Entamoeba histolytica hypothetical protein 0.0075 0.03 0.2775
Loa Loa (eye worm) jmjC domain-containing protein 0.001 0.0012 0.003
Trypanosoma cruzi trypanothione reductase, putative 0.0081 0.0328 0.0855
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0917 0.4056 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0028 0.0092 0.2803
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0464 0.2037 0.2037
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0188 0.049
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0369 0.0909
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0188 0.049
Schistosoma mansoni bromodomain containing protein 0.002 0.0058 0.0058
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0111 0.1006
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0464 0.2037 0.5022
Giardia lamblia Pyruvate kinase 0.0032 0.0111 0.1893
Schistosoma mansoni jumonji domain containing protein 0.001 0.0012 0.0012
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0026 0.0083 0.0747
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0369 0.0909
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0134 0.0134
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0011 0.0026
Echinococcus multilocularis beta LACTamase domain containing family member 0.0011 0.0016 0.0039
Echinococcus multilocularis axis inhibition protein axin 0.001 0.0011 0.0026
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0009 0.0007 0.0115
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0464 0.2037 0.5022
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0023 0.007 0.0643
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0013 0.0026 0.0064
Brugia malayi hypothetical protein 0.0214 0.0922 0.2272
Schistosoma mansoni 6-phosphofructokinase 0.0033 0.0115 0.0115
Leishmania major ATP-dependent phosphofructokinase 0.0033 0.0115 0.0299
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0034 0.0303
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0008 0.0001 0.0013
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0188 0.0463
Brugia malayi hypothetical protein 0.0062 0.0245 0.0605
Trichomonas vaginalis phosphofructokinase, putative 0.0009 0.0007 0.0061
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0188 0.319
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0499 0.1232
Brugia malayi Bromodomain containing protein 0.0013 0.0024 0.0059
Schistosoma mansoni hypothetical protein 0.0091 0.0374 0.0374
Toxoplasma gondii histone lysine demethylase JMJD6a 0.001 0.0012 0.0369
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0464 0.2037 0.5022
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0011 0.0026
Schistosoma mansoni ap endonuclease 0.0013 0.0026 0.0026
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0199 0.0491
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0028 0.0249
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0003 0.0003
Brugia malayi AF-10 protein 0.001 0.0013 0.0031
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0188 0.1695
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0188 0.049
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0188 0.1695
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0008 0.0001 0.0013
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0066 0.0172
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0188 0.5725
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0022 0.0201
Plasmodium falciparum glutathione reductase 0.0081 0.0328 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0043 0.0486
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0011 0.0016 0.0179
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0043 0.0112
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0043 0.0106
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0013 0.0026 0.0068
Echinococcus multilocularis acetylcholinesterase 0.0154 0.0653 0.1611
Loa Loa (eye worm) mbt repeat family protein 0.0015 0.0032 0.0078
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0003 0.0008
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0188 0.049
Brugia malayi Pre-SET motif family protein 0.0225 0.097 0.2391
Plasmodium vivax 6-phosphofructokinase, putative 0.0009 0.0007 0.0206
Mycobacterium leprae conserved hypothetical protein 0.0011 0.0016 0.0179
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0008 0.0001 0.0013
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0464 0.2037 0.5022
Echinococcus multilocularis nAChR subunit 0.0464 0.2037 0.5022
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.0427 0.1053
Trypanosoma cruzi C-14 sterol reductase, putative 0.0025 0.0079 0.0207
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0019 0.0053 0.013
Brugia malayi MAP kinase sur-1 0.005 0.0188 0.0463
Loa Loa (eye worm) hypothetical protein 0.0017 0.0041 0.01
Loa Loa (eye worm) LGC-31 protein 0.0464 0.2037 0.5022
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0111 0.0291
Echinococcus granulosus beta-adrenergic receptor kinase 0.001 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.001 0.0011 0.0026
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0188 0.0463
Echinococcus granulosus histone acetyltransferase MYST2 0.0017 0.0041 0.01
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0464 0.2037 0.5022
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.03 0.03
Echinococcus granulosus MAM 0.0032 0.011 0.027
Trichomonas vaginalis spcc417.12 protein, putative 0.0026 0.0083 0.0747
Loa Loa (eye worm) hypothetical protein 0.001 0.0011 0.0026
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0876 0.3874 0.9553
Echinococcus granulosus glycine receptor subunit beta 0.0464 0.2037 0.5022
Echinococcus multilocularis BC026374 protein (S09 family) 0.0026 0.0083 0.0204
Onchocerca volvulus 0.0011 0.0015 0.0037
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.004 0.0144 0.1329
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0011 0.0096
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0115 1
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0464 0.2037 0.5022
Schistosoma mansoni gliotactin 0.0026 0.0083 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0008 0.0001 0.0013
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0043 0.0106
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0188 0.049
Echinococcus multilocularis pyruvate kinase 0.0017 0.0041 0.0101
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0039
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0009 0.0007 0.0206
Loa Loa (eye worm) hypothetical protein 0.0464 0.2037 0.5022
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0013 0.0026 0.0793
Loa Loa (eye worm) hypothetical protein 0.0037 0.0134 0.033
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0008 0.0001 0.0003
Onchocerca volvulus 0.0015 0.0032 0.0078
Schistosoma mansoni nAChR subunit 0.0464 0.2037 0.2037
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0028 0.0092 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0001 0.0011
Schistosoma mansoni regulator of G protein signaling 0.001 0.0011 0.0011
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.025 0.1082 0.2667
Brugia malayi phosphofructokinase 0.0033 0.0115 0.0283
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0023 0.007 0.0181
Leishmania major cytochrome p450-like protein 0.0022 0.0066 0.0172
Brugia malayi jmjC domain containing protein 0.0039 0.0139 0.0344
Brugia malayi hypothetical protein 0.0214 0.0922 0.2272
Echinococcus granulosus axis inhibition protein axin 0.001 0.0011 0.0026
Loa Loa (eye worm) RGS-3 protein 0.001 0.0011 0.0026
Echinococcus multilocularis carboxylesterase 5A 0.0154 0.0653 0.1611
Echinococcus multilocularis acetylcholinesterase 0.0154 0.0653 0.1611
Schistosoma mansoni BC026374 protein (S09 family) 0.0026 0.0083 0.0083
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.001 0.0013 0.0031
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0066 0.0163
Trichomonas vaginalis bromodomain-containing protein, putative 0.0014 0.0028 0.0253
Schistosoma mansoni phosphatidylserine receptor 0.001 0.0012 0.0012
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0043 0.1307
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0464 0.2037 0.2037
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0137 0.0337
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0043 0.0112
Echinococcus multilocularis small conductance calcium activated potassium 0.0132 0.0554 0.1365
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0023 0.007 0.0181
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0041 0.1251
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0016 0.0041
Schistosoma mansoni regulator of G protein signaling 0.001 0.0011 0.0011
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0001 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.0011 0.0016 0.0142
Mycobacterium tuberculosis Conserved protein 0.0011 0.0016 0.0179
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0015 0.0032 0.0078
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0081 0.0328 0.3716
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0111 0.0275
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0028 0.0249
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0016 0.0481
Brugia malayi jmjC domain containing protein 0.001 0.0012 0.003
Brugia malayi A-kinase anchor protein 10, precursor 0.001 0.0011 0.0026
Echinococcus multilocularis musashi 0.0011 0.0015 0.0037
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0111 0.0275
Loa Loa (eye worm) hypothetical protein 0.0014 0.003 0.0073
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0214 0.0922 0.2272
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0028 0.0092 0.024
Plasmodium falciparum glutathione reductase 0.0028 0.0092 0.2803
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0078
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.001 0.0009 0.0025
Schistosoma mansoni hypothetical protein 0.001 0.0013 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0008 0.0001 0.0013
Trypanosoma cruzi sterol C-24 reductase, putative 0.0025 0.0079 0.0207
Loa Loa (eye worm) hypothetical protein 0.0154 0.0653 0.1611
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0066 0.0163
Loa Loa (eye worm) hypothetical protein 0.025 0.1082 0.2667
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0214 0.0922 0.2272
Loa Loa (eye worm) Smad1 0.0008 0.0003 0.0008
Onchocerca volvulus Putative nachr subunit 0.0464 0.2037 0.5022
Plasmodium vivax glutathione reductase, putative 0.0081 0.0328 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0022 0.0201
Brugia malayi Thioredoxin reductase 0.0081 0.0328 0.0809
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0043 0.039
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0043 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0043 0.039
Brugia malayi 6-phosphofructokinase 0.0033 0.0115 0.0283
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0028 0.0092 0.825
Brugia malayi beta-lactamase family protein 0.0011 0.0016 0.0039
Brugia malayi beta-lactamase family protein 0.0011 0.0016 0.0039
Brugia malayi PXA domain containing protein 0.001 0.0011 0.0026
Giardia lamblia GTOR 0.0023 0.007 0.1182
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0008 0.0001 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0008 0.0001 0.0013
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0111 0.0275
Schistosoma mansoni neurotransmitter gated ion channel 0.0214 0.0922 0.0922
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0369 0.0369
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0092 0.024
Onchocerca volvulus 0.0464 0.2037 0.5022
Schistosoma mansoni jumonji domain containing protein 0.0082 0.0332 0.0332
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0111 0.1006
Onchocerca volvulus 0.0032 0.011 0.027
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0111 0.0111
Brugia malayi hypothetical protein 0.0214 0.0922 0.2272
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.001 0.0012 0.0032
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0162 0.04
Mycobacterium tuberculosis Carboxylesterase LipT 0.0026 0.0083 0.0937
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.007 0.0628
Trichomonas vaginalis ap endonuclease, putative 0.0013 0.0026 0.0235
Loa Loa (eye worm) 6-phosphofructokinase 0.0033 0.0115 0.0283
Entamoeba histolytica hypothetical protein 0.001 0.0011 0.0098
Echinococcus multilocularis Smad4 0.0008 0.0003 0.0008
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0008 0.0001 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0011 0.0096
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0011 0.0016 0.0039
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0257 0.0633
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0045 0.011
Treponema pallidum exodeoxyribonuclease (exoA) 0.0013 0.0026 0.2268
Giardia lamblia PHD finger protein 15 0.0032 0.0107 0.1821
Trichomonas vaginalis phosphofructokinase, putative 0.0009 0.0007 0.0061
Leishmania major trypanothione reductase 0.0081 0.0328 0.0855
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0464 0.2037 0.5022
Loa Loa (eye worm) intermediate filament protein 0.0011 0.0015 0.0037
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0008 0.0001 0.0003
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.001 0.0011 0.0011
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0043 0.0112
Mycobacterium tuberculosis Probable dehydrogenase 0.0185 0.0791 0.8958
Plasmodium vivax SET domain protein, putative 0.0032 0.0111 0.3371
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0139 0.0139
Echinococcus granulosus 6 phosphofructokinase 0.0033 0.0115 0.0283
Schistosoma mansoni protein phosphatase 2C 0.001 0.0012 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0188 0.1695
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.027
Loa Loa (eye worm) hypothetical protein 0.0256 0.1106 0.2728
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0204
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0499 0.1232
Echinococcus multilocularis lamin 0.0011 0.0015 0.0037
Brugia malayi Protein kinase domain containing protein 0.0269 0.1165 0.2872
Schistosoma mansoni acetylcholine receptor subunit beta 0.0214 0.0922 0.0922
Trichomonas vaginalis ap endonuclease, putative 0.0013 0.0026 0.0235
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0008 0.0001 0.0098
Echinococcus multilocularis regulator of G protein signaling 3 0.001 0.0011 0.0026
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0023 0.007 0.007
Mycobacterium ulcerans carboxylesterase, LipT 0.0026 0.0083 0.7212
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0028 0.0092 0.8015
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0111 0.0275
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0023 0.007 0.0643
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0008 0.0001 0.0013
Entamoeba histolytica hypothetical protein 0.004 0.0144 0.1329
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0008 0.0001 0.0013
Onchocerca volvulus 0.0256 0.1108 0.2732
Schistosoma mansoni hypothetical protein 0.0032 0.011 0.011
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0041 0.1251
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.003
Trypanosoma cruzi C-14 sterol reductase, putative 0.0025 0.0079 0.0207
Plasmodium falciparum thioredoxin reductase 0.0081 0.0328 1
Trichomonas vaginalis phosphofructokinase, putative 0.0009 0.0007 0.0061
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0028 0.0092 0.024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0369 0.0909
Brugia malayi regulator of G-protein signaling egl-10 0.001 0.0011 0.0026
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0043 0.0106
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Loa Loa (eye worm) hypothetical protein 0.001 0.0011 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.007 0.0628
Schistosoma mansoni neurotransmitter gated ion channel 0.025 0.1082 0.1082
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0015 0.0032 0.0032
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0111 0.0291
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0092 0.024
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.0427 0.1053
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0039
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0464 0.2037 0.5022
Loa Loa (eye worm) hypothetical protein 0.0054 0.0208 0.0512
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0028 0.0255
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.0011 0.0026
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.001 0.0012 0.0032
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0023 0.007 0.0181
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0464 0.2037 0.5022
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0011 0.0016 0.0179
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0092 0.024
Schistosoma mansoni hypothetical protein 0.0075 0.03 0.03
Mycobacterium ulcerans lipase LipD 0.0011 0.0016 0.1375
Onchocerca volvulus 0.0011 0.0015 0.0037
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0043 0.0106
Echinococcus multilocularis geminin 0.0068 0.027 0.0666
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0049 0.0127
Loa Loa (eye worm) hypothetical protein 0.025 0.1082 0.2667
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0023 0.007 0.0181
Loa Loa (eye worm) carboxylesterase 0.0154 0.0653 0.1611
Toxoplasma gondii 6-phosphofructokinase 0.0009 0.0007 0.0206
Echinococcus granulosus pyruvate kinase 0.0017 0.0041 0.0101
Schistosoma mansoni axis inhibition protein axin 0.001 0.0011 0.0011
Trichomonas vaginalis glutathione reductase, putative 0.0028 0.0092 0.083
Brugia malayi vesicular acetylcholine transporter unc-17 0.0917 0.4056 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0011 0.0016 0.0142
Giardia lamblia Histone acetyltransferase GCN5 0.0012 0.002 0.0339
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0188 0.1695
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0464 0.2037 0.5022
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0013 0.0387
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0013 0.0026 0.0442
Mycobacterium tuberculosis Probable hydrolase 0.0011 0.0016 0.0179
Echinococcus granulosus muscleblind protein 0.0161 0.0687 0.1693
Echinococcus granulosus polycomb protein SCMH1 0.0015 0.0032 0.0078
Brugia malayi Cation transporter family protein 0.0464 0.2037 0.5022
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0008 0.0001 0.0098
Brugia malayi Carboxylesterase family protein 0.0026 0.0083 0.0204
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0464 0.2037 0.5022
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0011 0.0096
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Schistosoma mansoni nAChR subunit 0.0464 0.2037 0.2037
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0214 0.0922 0.2272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0049 0.0438
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Brugia malayi PHD-finger family protein 0.0011 0.0015 0.0038
Echinococcus multilocularis para nitrobenzyl esterase 0.0026 0.0083 0.0204
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0041 0.1251
Loa Loa (eye worm) hypothetical protein 0.0026 0.0083 0.0204
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0011 0.0016 0.0039
Loa Loa (eye worm) hypothetical protein 0.0214 0.0922 0.2272
Schistosoma mansoni regulator of G protein signaling 0.001 0.0011 0.0011
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0464 0.2037 0.5022
Schistosoma mansoni smad 0.0008 0.0003 0.0003
Brugia malayi Intermediate filament tail domain containing protein 0.0011 0.0015 0.0037
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0464 0.2037 0.5022
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0464 0.2037 0.2037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0068 0.0167
Schistosoma mansoni lamin 0.0011 0.0015 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0134 0.0134
Loa Loa (eye worm) GABA receptor subunit 0.025 0.1082 0.2667
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0464 0.2037 0.5022
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0008 0.0001 0.0003
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0021 0.0059 0.0145
Schistosoma mansoni acetylcholinesterase 0.0026 0.0083 0.0083
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0016 0.0037 0.0091
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0111 0.0275
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0107 0.3269

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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