Detailed information for compound 621994

Basic information

Technical information
  • TDR Targets ID: 621994
  • Name: 2-[[3-(4-ethoxyphenyl)-4-oxo-6,7-dihydrothien o[3,2-d]pyrimidin-2-yl]sulfanyl]-N-[(4-fluoro phenyl)methyl]acetamide
  • MW: 471.567 | Formula: C23H22FN3O3S2
  • H donors: 1 H acceptors: 2 LogP: 4 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)n1c(SCC(=O)NCc2ccc(cc2)F)nc2c(c1=O)SCC2
  • InChi: 1S/C23H22FN3O3S2/c1-2-30-18-9-7-17(8-10-18)27-22(29)21-19(11-12-31-21)26-23(27)32-14-20(28)25-13-15-3-5-16(24)6-4-15/h3-10H,2,11-14H2,1H3,(H,25,28)
  • InChiKey: WREZPDULXJAOAH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[[3-(4-ethoxyphenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]thio]-N-[(4-fluorophenyl)methyl]acetamide
  • 2-[[3-(4-ethoxyphenyl)-4-keto-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]thio]-N-(4-fluorobenzyl)acetamide
  • 2-[[3-(4-ethoxyphenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl]-N-[(4-fluorophenyl)methyl]ethanamide
  • EU-0022227

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0002 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.001 0.002
Echinococcus multilocularis transfer RNA-Lys 0.0033 0.0005 0.0005
Plasmodium vivax phosphoglycerate kinase, putative 0.0172 0.0041 0.0508
Trypanosoma brucei heat shock protein, putative 0.0064 0.0013 0.0103
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0002 0.0002
Toxoplasma gondii heat shock protein HSP90 0.0064 0.0013 0.0146
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0006 0.0013
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.348 0.0871 0.701
Loa Loa (eye worm) inositol-1 0.0036 0.0006 0.0014
Mycobacterium ulcerans putative regulatory protein 0.0041 0.0008 0.1754
Onchocerca volvulus 0.0082 0.0018 0.0622
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0061 0.0012 0.0033
Brugia malayi sulfakinin receptor protein 0.0051 0.001 0.0028
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0026 0.0004 0.0004
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0035 0.0006 0.0194
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0001 0.0001
Echinococcus multilocularis serotonin receptor 0.0051 0.001 0.001
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0005 0.0181
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0001 0.0012
Plasmodium vivax heat shock protein, putative 0.0026 0.0004 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0002 0.0004
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.4959 0.1242 0.3357
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0002 0.0075
Toxoplasma gondii cytochrome p450 superfamily protein 0.0035 0.0006 0.0066
Echinococcus granulosus tumor protein p63 0.0681 0.0168 0.0168
Schistosoma mansoni pyruvate dehydrogenase 0.0013 0.0001 0.0001
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0002 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.001 0.0321
Trypanosoma brucei heat shock protein, putative 0.0064 0.0013 0.0103
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.001 0.001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.4959 0.1242 0.3358
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0041 0.011
Loa Loa (eye worm) phosphatidylinositol 3 0.1149 0.0286 0.0628
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0002 0.0007
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0011 0.0025
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0073 0.0016 0.0016
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1149 0.0286 0.2298
Schistosoma mansoni fkbp-rapamycin associated protein 0.2222 0.0555 0.111
Trichomonas vaginalis DNA helicase recq, putative 0.0017 0.0002 0.0004
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0067 0.0014 0.0014
Brugia malayi AMP-binding enzyme family protein 0.007 0.0015 0.004
Entamoeba histolytica phosphofructokinase, putative 0.0099 0.0022 0.0058
Plasmodium vivax 6-phosphofructokinase, putative 0.0027 0.0004 0.0047
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0002 0.0067
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0016 0.0001 0.0013
Mycobacterium tuberculosis Conserved hypothetical protein 0.1149 0.0286 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0035 0.0006 0.0194
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0002 0.0002
Schistosoma mansoni voltage-gated cation channel 0.0033 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.1149 0.0286 0.0628
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0041 0.011
Brugia malayi serine/threonine-protein kinase plk-2 0.0174 0.0041 0.0111
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0016 0.0001 0.0002
Schistosoma mansoni adenoreceptor 0.0051 0.001 0.002
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0021 0.0057
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.001 0.0022
Echinococcus multilocularis expressed conserved protein 0.009 0.002 0.002
Echinococcus granulosus geminin 0.0329 0.008 0.008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.001 0.001
Echinococcus multilocularis sex peptide receptor 0.0051 0.001 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0029 0.0077
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0011 0.0025
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0057 0.0012 0.0031
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0033 0.0006 0.0015
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0001 0.0001
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0006 0.0006
Plasmodium vivax DNA gyrase subunit B, putative 0.0013 0.0001 0.0004
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.317 0.0793 0.1743
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0008 0.0092
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0033 0.0006 0.0061
Trypanosoma brucei heat shock protein 90, putative 0.0064 0.0013 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0004 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0035 0.0006 0.0194
Schistosoma mansoni endoplasmin 0.0064 0.0013 0.0027
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0033 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Trypanosoma brucei phosphoglycerate kinase, putative 0.0063 0.0013 0.0102
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0083 0.0018 0.0049
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Echinococcus granulosus regulator of G protein signaling 7 0.0017 0.0002 0.0002
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0002 0.0005
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0035 0.0006 0.1388
Brugia malayi Serotonin receptor 0.0469 0.0115 0.0311
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0002 0.0005
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.354 0.0886 0.2395
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0122 0.0028 0.0061
Echinococcus granulosus g protein coupled receptor 0.0051 0.001 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0001 0.0002
Mycobacterium ulcerans putative regulatory protein 0.0033 0.0005 0.124
Echinococcus granulosus netrin receptor unc 5 0.0013 0.0001 0.0001
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0002 0.0476
Schistosoma mansoni biogenic amine receptor 0.0051 0.001 0.002
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0013 0.0001 0.0013
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.7743 0.1941 0.1941
Brugia malayi Csnk2b protein 0.0033 0.0006 0.0015
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.001 0.001
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0016 0.0001 0.0002
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0002 0.0003
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0002 0.0476
Schistosoma mansoni nuclear hormone receptor 0.002 0.0002 0.0005
Trichomonas vaginalis set domain proteins, putative 0.0193 0.0046 0.0123
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0012
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0035 0.0006 0.1388
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.3636 0.091 0.2459
Trichomonas vaginalis PIKK family atypical protein kinase 0.2244 0.0561 0.1515
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Echinococcus multilocularis heat shock protein 90 0.0064 0.0013 0.0013
Onchocerca volvulus 0.0051 0.001 0.0352
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.1149 0.0286 0.3603
Trichomonas vaginalis PIKK family atypical protein kinase 0.3528 0.0883 0.2386
Trichomonas vaginalis heat shock protein, putative 0.0051 0.001 0.0027
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1149 0.0286 0.0772
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0015 0.0039
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.4959 0.1242 0.3358
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0012 0 0.0001
Echinococcus granulosus Regulator of G protein signaling 20 0.0017 0.0002 0.0002
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0002 0.008
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0009 0.0024
Echinococcus multilocularis regulator of G protein signaling 0.0017 0.0002 0.0002
Brugia malayi Probable DNA topoisomerase II 0.0013 0.0001 0.0001
Plasmodium falciparum casein kinase II beta chain 0.0033 0.0006 0.0069
Trypanosoma brucei target of rapamycin kinase 3, putative 0.3588 0.0898 0.7229
Trypanosoma cruzi heat shock protein, putative 0.0026 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0194 0.0046 0.0101
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0047 0.0009 0.0024
Echinococcus granulosus 6 phosphofructokinase 0.0099 0.0022 0.0022
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0021 0.0002 0.0002
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 1.9928 0.5001 0.5001
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.001 0.0022
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0115 0.0026 0.6388
Leishmania major cytochrome p450-like protein 0.0056 0.0011 0.003
Leishmania major hypothetical protein, conserved 0.0016 0.0001 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0002 0.0476
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0013
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.001 0.001
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0002 0.0002
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0002 0.0005
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.001 0.002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.001 0.0028
Echinococcus multilocularis high voltage activated calcium channel beta 0.0079 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.2318 0.0579 0.1565
Trichomonas vaginalis PIKK family atypical protein kinase 0.1072 0.0266 0.072
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0012 0.0031
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.3636 0.091 0.091
Toxoplasma gondii phosphofructokinase PFKII 0.0027 0.0004 0.0042
Schistosoma mansoni hypothetical protein 0.0068 0.0014 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0001 0.0003
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0001 0.0183
Loa Loa (eye worm) hypothetical protein 0.7044 0.1766 0.388
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Giardia lamblia Hypothetical protein 0.0016 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.3636 0.091 0.246
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0001 0.0002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0006 0.0017
Echinococcus granulosus serine:threonine protein kinase SMG1 0.2222 0.0555 0.0555
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.3528 0.0883 0.2386
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0 0.0001
Schistosoma mansoni hypothetical protein 0.0031 0.0005 0.001
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.2222 0.0555 0.1499
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Schistosoma mansoni hypothetical protein 0.0396 0.0097 0.0194
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.001 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0009 0.0023
Loa Loa (eye worm) phosphatidylinositol 3 0.1149 0.0286 0.0628
Loa Loa (eye worm) heat shock protein 90 0.0064 0.0013 0.0029
Echinococcus granulosus axis inhibition protein axin 0.0017 0.0002 0.0002
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.0013 0.0034
Giardia lamblia Hypothetical protein 0.1149 0.0286 0.1114
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0001 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0001 0.0002
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 1.0214 0.2562 1
Entamoeba histolytica protein kinase rad3, putative 0.2222 0.0555 0.1499
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0002 0.0004
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0035 0.0006 0.0045
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0006 0.0006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 1.4747 0.37 1
Toxoplasma gondii CMGC kinase, CK2 family 0.0124 0.0029 0.0317
Schistosoma mansoni blooms syndrome DNA helicase 0.0014 0.0001 0.0001
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0172 0.0041 0.0109
Loa Loa (eye worm) RecQ helicase 0.0017 0.0002 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0001 0.0002
Plasmodium vivax hypothetical protein, conserved 0.1149 0.0286 0.3602
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.001 0.001
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.2408 0.0602 0.1322
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0026 0.092
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0002 0.0005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0024 0.0806
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0021 0.0021
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0013
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0051 0.001 0.001
Brugia malayi RNA binding protein 0.0061 0.0013 0.0034
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 1.2003 0.3011 0.8138
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0051 0.001 0.0028
Echinococcus granulosus regulator of G protein signaling 3 0.0017 0.0002 0.0002
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0001 0.0001
Schistosoma mansoni heat shock protein 0.0026 0.0004 0.0008
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0035 0.0006 0.1388
Loa Loa (eye worm) hypothetical protein 0.0068 0.0014 0.0031
Leishmania major phosphatidylinositol 4-kinase, putative 0.1149 0.0286 0.0766
Trypanosoma cruzi hypothetical protein, conserved 1.3716 0.3441 0.93
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1149 0.0286 0.0773
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0032 0.0032
Brugia malayi CHE-14 protein 0.0041 0.0008 0.002
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0001 0.0026
Toxoplasma gondii 6-phosphofructokinase 0.0027 0.0004 0.0042
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0001 0.0002
Echinococcus granulosus g protein coupled receptor 0.0051 0.001 0.001
Trypanosoma brucei Casein kinase II 0.0124 0.0029 0.0225
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0088 0.0019 0.0052
Brugia malayi Cytochrome P450 family protein 0.0035 0.0006 0.0016
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.001 0.002
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0002 0.0021
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.1149 0.0286 0.3602
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0015 0.0502
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0035 0.0006 0.0194
Brugia malayi Cytochrome P450 family protein 0.0107 0.0024 0.0065
Echinococcus granulosus GPCR family 2 0.0031 0.0005 0.0005
Toxoplasma gondii thioredoxin reductase 0.0046 0.0009 0.0096
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0001 0.0002
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0006 0.0012
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.3588 0.0898 0.2427
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0004 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0004 0.001
Echinococcus granulosus cytochrome P450 2K1 0.0035 0.0006 0.0006
Schistosoma mansoni phosphoglycerate kinase 0.0172 0.0041 0.0081
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.1258 0.0313 0.0313
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0013 0.0001 0.0001
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Trypanosoma brucei phosphoglycerate kinase 0.0172 0.0041 0.0322
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0004 0.001
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0022 0.0043
Echinococcus granulosus lamin 0.0022 0.0003 0.0003
Plasmodium falciparum DNA topoisomerase 2 0.0013 0.0001 0.0004
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0002 0.0004
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0029 0.0077
Toxoplasma gondii ck2 beta subunit 0.0033 0.0006 0.0061
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0002 0.0005
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.1149 0.0286 0.0771
Entamoeba histolytica casein kinase, putative 0.0124 0.0029 0.0076
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0033 0.0006 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0015 0.0041
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0006 0.0006
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0002 0.008
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1102 0.0274 0.0739
Toxoplasma gondii hypothetical protein 0.0072 0.0015 0.0169
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.317 0.0793 1
Loa Loa (eye worm) RGS-3 protein 0.0017 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Loa Loa (eye worm) 6-phosphofructokinase 0.0099 0.0022 0.0048
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0035 0.0006 0.0194
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0011 0.2678
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0002 0.0003
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.001 0.001
Echinococcus granulosus heat shock protein 90 0.0064 0.0013 0.0013
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Schistosoma mansoni phosphoglycerate kinase 0.0172 0.0041 0.0081
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.3528 0.0883 0.2386
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0001 0.0003
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0046 0.0009 0.0023
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.3584 0.0897 0.2423
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0024 0.0003 0.0721
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0035 0.0006 0.1388
Brugia malayi M-phase phosphoprotein, mpp8 0.0082 0.0018 0.0048
Leishmania major phosphatidylinositol 3-kinase, putative 0.317 0.0793 0.2126
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0172 0.0041 0.0451
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0002 0.0476
Onchocerca volvulus 0.0051 0.001 0.0352
Echinococcus granulosus voltage dependent calcium channel 0.0033 0.0006 0.0006
Treponema pallidum NADH oxidase 0.0016 0.0001 0.0183
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0051 0.001 0.001
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0002 0.0002
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.001 0.0028
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.001 0.0028
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0088 0.0019 0.0051
Schistosoma mansoni hypothetical protein 0.0039 0.0007 0.0014
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.3588 0.0898 0.2408
Schistosoma mansoni lamin 0.0022 0.0003 0.0006
Echinococcus granulosus neuropeptide receptor A26 0.0051 0.001 0.001
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0001 0.0001
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0001 0.0003
Entamoeba histolytica heat shock protein 90, putative 0.0064 0.0013 0.0035
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0013 0.0001 0.0001
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0088 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.0052 0.001 0.0023
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.001 0.001
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0002 0.0015
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0006 0.0006
Plasmodium vivax glutathione reductase, putative 0.0046 0.0009 0.0108
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.001 0.002
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0028 0.0061
Schistosoma mansoni hypothetical protein 0.0042 0.0008 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0029 0.0077
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.001 0.001
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0002 0.008
Plasmodium vivax endoplasmin, putative 0.0064 0.0013 0.0165
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.3636 0.091 0.7326
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0088 0.0019 0.0052
Onchocerca volvulus 0.1149 0.0286 1
Chlamydia trachomatis phosphoglycerate kinase 0.0172 0.0041 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0035 0.0006 0.0194
Leishmania major developmentally regulated phosphoprotein-like protein 0.0013 0.0001 0.0001
Plasmodium falciparum phosphatidylinositol 3-kinase 0.317 0.0793 1
Echinococcus granulosus high voltage activated calcium channel beta 0.0079 0.0017 0.0017
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0067 0.0014 0.0038
Echinococcus multilocularis netrin receptor unc 5 0.0013 0.0001 0.0001
Echinococcus granulosus voltage gated potassium channel 0.0021 0.0002 0.0002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0001 0.0002
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0013 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0036 0.0006 0.0013
Echinococcus multilocularis neuropeptide s receptor 0.0051 0.001 0.001
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0021 0.0021
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0024 0.0818
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Trypanosoma cruzi heat shock protein 90, putative 0.0051 0.001 0.0026
Onchocerca volvulus Serine\/threonine kinase homolog 0.0174 0.0041 0.143
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0002 0.0002
Loa Loa (eye worm) cytochrome P450 0.0035 0.0006 0.0013
Leishmania major DNA topoisomerase ii 0.0013 0.0001 0.0001
Trypanosoma cruzi polo-like protein kinase, putative 0.0174 0.0041 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.354 0.0886 0.2395
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0021 0.0002 0.0002
Onchocerca volvulus 0.0051 0.001 0.0352
Schistosoma mansoni opsin-like receptor 0.0051 0.001 0.002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0004 0.0009
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0002 0.0476
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0001 0.0001
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0035 0.0006 0.0016
Loa Loa (eye worm) calcium channel 0.0033 0.0006 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.001 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0005
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0015 0.0514
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0009 0.0009
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0292 0.0071 0.0191
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Brugia malayi G protein-coupled receptor 0.0051 0.001 0.0028
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0035 0.0006 0.1388
Trichomonas vaginalis PIKK family atypical protein kinase 0.348 0.0871 0.2354
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Mycobacterium ulcerans 6-phosphofructokinase 0.0099 0.0022 0.5388
Schistosoma mansoni myosin xvIII 0.0051 0.001 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.233 0.0582 0.1573
Loa Loa (eye worm) phosphatidylinositol 3 0.1149 0.0286 0.0628
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0015 0.358
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0027 0.0004 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.001 0.002
Loa Loa (eye worm) heat shock protein 75 0.0026 0.0004 0.0008
Schistosoma mansoni 60S ribosomal protein L21 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0002 0.0006
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0008 0.0258
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.3636 0.091 0.246
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0002 0.0002
Onchocerca volvulus 0.1149 0.0286 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.001 0.001
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.317 0.0793 0.2143
Schistosoma mansoni lamin 0.0022 0.0003 0.0006
Trypanosoma brucei trypanothione reductase 0.0046 0.0009 0.0066
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.017 0.004 0.0088
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.317 0.0793 0.0793
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0051 0.001 0.0345
Giardia lamblia Kinase, CMGC GSK 0.0046 0.0009 0.0033
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0005 0.0005
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.001 0.001
Loa Loa (eye worm) 6-phosphofructokinase 0.0099 0.0022 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0006
Schistosoma mansoni hypothetical protein 0.0051 0.001 0.002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1149 0.0286 0.0773
Echinococcus multilocularis regulator of G protein signaling 7 0.0017 0.0002 0.0002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0001 0.0002
Entamoeba histolytica hypothetical protein 0.1149 0.0286 0.0772
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0075 0.0016 0.0042
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0013
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0099 0.0022 0.0173
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0002 0.0002
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0001 0.0003
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0003
Toxoplasma gondii heat shock protein 90, putative 0.0064 0.0013 0.0146
Echinococcus multilocularis cpg binding protein 0.0029 0.0005 0.0005
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0063 0.0013 0.0034
Mycobacterium tuberculosis Probable reductase 0.0105 0.0024 0.0806
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Echinococcus granulosus regulator of G protein signaling 3 0.0017 0.0002 0.0002
Plasmodium vivax casein kinase II beta chain, putative 0.0033 0.0006 0.0068
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0001 0.0003
Entamoeba histolytica phosphofructokinase, putative 0.0099 0.0022 0.0058
Entamoeba histolytica heat shock protein 90, putative 0.0064 0.0013 0.0035
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0051 0.001 0.0352
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.001 0.001
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0024 0.0806
Plasmodium falciparum casein kinase II beta chain 0.0033 0.0006 0.0069
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0051 0.001 0.2371
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0035 0.0006 0.1388
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0006 0.0006
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0002 0.0025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0002 0.0002
Leishmania major protein kinase, putative 0.0015 0.0001 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0002 0.0007
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0002 0.0005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0006 0.0017
Loa Loa (eye worm) endoplasmin 0.0064 0.0013 0.0029
Entamoeba histolytica hypothetical protein 0.1149 0.0286 0.0772
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0172 0.0041 0.1412
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.0015 0.358
Schistosoma mansoni histamine h1 receptor 0.0051 0.001 0.002
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0035 0.0006 0.0194
Trichomonas vaginalis sensor histidine kinase, putative 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0004 0.0007
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0006 0.0016
Trichomonas vaginalis DNA topoisomerase II, putative 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0021 0.0002 0.008
Echinococcus multilocularis protein dispatched 1 0.0047 0.0009 0.0009
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0002 0.0004
Plasmodium vivax casein kinase II beta chain, putative 0.0033 0.0006 0.0068
Echinococcus granulosus heat shock protein 90 0.0051 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.3576 0.0895 0.2419
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0002 0.0005
Leishmania major ATP-dependent phosphofructokinase 0.0099 0.0022 0.0059
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0013 0.0001 0.0001
Plasmodium falciparum glutathione reductase 0.0046 0.0009 0.0108
Schistosoma mansoni hypothetical protein 0.0329 0.008 0.016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.001 0.001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0022 0.0003 0.0006
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0002 0.0005
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0027 0.0004 0.0861
Echinococcus granulosus neuropeptide s receptor 0.0051 0.001 0.001
Echinococcus granulosus serotonin receptor 0.0051 0.001 0.001
Brugia malayi Thioredoxin reductase 0.0046 0.0009 0.0024
Onchocerca volvulus 0.0193 0.0046 0.1596
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0002 0.0476
Entamoeba histolytica hypothetical protein 0.0036 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Echinococcus multilocularis casein kinase ii subunit alpha 0.0124 0.0029 0.0029
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0051 0.001 0.0026
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0075 0.0016 0.0042
Brugia malayi nuclear hormone receptor 0.002 0.0002 0.0006
Brugia malayi Phosphoglycerate kinase 0.0172 0.0041 0.0109
Leishmania major hypothetical protein, conserved 0.0026 0.0004 0.0009
Echinococcus multilocularis expressed protein 0.0339 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0172 0.0041 0.0089
Brugia malayi ecdysteroid receptor 0.002 0.0002 0.0006
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0001 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.001 0.001
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0035 0.0006 0.1388
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0017 0.0002 0.0002
Echinococcus multilocularis lamin 0.0022 0.0003 0.0003
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0057 0.0012 0.0012
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0051 0.001 0.001
Brugia malayi steroid hormone receptor 0.002 0.0002 0.0006
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0002 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0004 0.0007
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0124 0.0029 0.0357
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0002 0.0011
Brugia malayi SH2 domain containing protein 0.0646 0.016 0.0431
Schistosoma mansoni inositol monophosphatase 0.0036 0.0006 0.0013
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.1149 0.0286 0.0286
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0005
Onchocerca volvulus 0.0051 0.001 0.0352
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0047 0.0009 0.0024
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.007 0.0015 0.358
Schistosoma mansoni voltage-gated potassium channel 0.0073 0.0016 0.0031
Echinococcus granulosus axis inhibition protein axin 0.0017 0.0002 0.0002
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0026 0.0004 0.0009
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.317 0.0793 0.0793
Loa Loa (eye worm) hypothetical protein 0.7743 0.1941 0.4266
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0002 0.0476
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0088 0.0019 0.0052
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0006 0.1437
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.005 0.001 0.0022
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0002 0.0005
Loa Loa (eye worm) phosphatidylinositol 3 1.8139 0.4552 1
Trypanosoma brucei heat shock protein, putative 0.0064 0.0013 0.0103
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0005
Echinococcus granulosus regulator of G protein signaling 7 0.0017 0.0002 0.0002
Schistosoma mansoni casein kinase II beta subunit 0.0033 0.0006 0.0011
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0008 0.0017
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.2252 0.0563 0.152
Trichomonas vaginalis PIKK family atypical protein kinase 0.3588 0.0898 0.2427
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0046 0.0009 0.0023
Treponema pallidum phosphoglycerate kinase 0.0172 0.0041 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0017 0.0002 0.0004
Echinococcus multilocularis 6 phosphofructokinase 0.0099 0.0022 0.0022
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.2222 0.0555 0.0555
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0001 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0004 0.0009
Loa Loa (eye worm) phosphatidylinositol 3 0.1149 0.0286 0.0628
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Leishmania major cytochrome p450-like protein 0.0035 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.1258 0.0313 0.0688
Brugia malayi follicle stimulating hormone receptor 0.026 0.0063 0.0169
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0001 0.0183
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0002 0.0002
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0033 0.0006 0.0006
Plasmodium vivax phosphodiesterase gamma, putative 0.0016 0.0001 0.0013
Echinococcus multilocularis GPCR, family 2 0.0031 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.007 0.0015 0.0033
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0001 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.001 0.001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0174 0.0041 0.0041
Plasmodium falciparum phosphodiesterase delta, putative 0.0016 0.0001 0.0013
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0001 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0002 0.0006
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0088 0.0019 0.0052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.001 0.002
Brugia malayi Endoplasmin precursor 0.0064 0.0013 0.0036
Echinococcus granulosus expressed conserved protein 0.0155 0.0036 0.0036
Mycobacterium leprae conserved hypothetical protein 0.1149 0.0286 1
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 3.9839 1 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0155 0.0036 0.0072
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.001 0.001
Entamoeba histolytica protein kinase, putative 0.0046 0.0009 0.0023
Onchocerca volvulus 0.007 0.0015 0.0514
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 1.2957 0.3251 0.8786
Echinococcus multilocularis bloom syndrome protein 0.0017 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.001 0.002
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0016 0.0001 0.0003
Brugia malayi regulator of G-protein signaling egl-10 0.0017 0.0002 0.0004
Onchocerca volvulus 0.0021 0.0002 0.008
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0002 0.0028
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0043 0.0008 0.0018
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0002 0.0476
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.001 0.0028
Giardia lamblia Grp94/Hsp90 0.0051 0.001 0.0037
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0088 0.0019 0.0019
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0016 0.0001 0.0001
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0002 0.0005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0172 0.0041 0.0108
Toxoplasma gondii GAF domain-containing protein 0.0041 0.0008 0.0082
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0292 0.0071 0.0155
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0017 0.0002 0.0003
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.7743 0.1941 0.1941
Schistosoma mansoni hypothetical protein 0.1149 0.0286 0.0572
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.001 0.001
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0033 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0002 0.0005
Schistosoma mansoni cpg binding protein 0.0029 0.0005 0.0009
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.317 0.0793 0.2143
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0046 0.0009 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0002 0.0067
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0013 0.0013
Leishmania major hypothetical protein, conserved 0.0061 0.0013 0.0033
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0088 0.0019 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.001 0.001
Schistosoma mansoni ankyrin 23/unc44 0.0013 0.0001 0.0001
Brugia malayi hypothetical protein 0.0148 0.0035 0.0093
Schistosoma mansoni ap endonuclease 0.0018 0.0002 0.0004
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0004 0.0009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.001 0.001
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0016 0.0001 0.0003
Schistosoma mansoni cpg binding protein 0.0028 0.0004 0.0009
Onchocerca volvulus 0.0051 0.001 0.0352
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0041 0.011
Echinococcus multilocularis axis inhibition protein axin 0.0017 0.0002 0.0002
Echinococcus granulosus FTZ F1 alpha 0.002 0.0002 0.0002
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0077 0.0017 0.0044
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0002 0.0006
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0001 0.0001
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0013 0.0001 0.0013
Echinococcus granulosus histone lysine methyltransferase setb 0.0025 0.0004 0.0004
Treponema pallidum heat shock protein 90 0.0051 0.001 0.2371
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0004 0.001
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0073 0.0016 0.0016
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0002 0.0003
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0001 0.0183
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0013 0.0001 0.0013
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0001 0.0001
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0077 0.0017 0.0044
Echinococcus multilocularis voltage gated potassium channel 0.0021 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.001 0.001
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0002 0.0006
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0005 0.0011
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.5002 0.1253 0.2506
Brugia malayi Melatonin receptor type 1A 0.0051 0.001 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0041 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0041 0.011
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0035 0.0006 0.1388
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0002 0.0042
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.1149 0.0286 0.0772
Echinococcus multilocularis orexin receptor type 2 0.0051 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.001 0.002
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0027 0.0004 0.001
Trypanosoma brucei heat shock protein, putative 0.0064 0.0013 0.0103
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.4959 0.1242 0.3358
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0022 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0015 0.0041
Schistosoma mansoni hypothetical protein 0.0051 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0017 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Echinococcus multilocularis neuropeptide receptor 0.0051 0.001 0.001
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.001 0.0022
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0016 0.0001 0.0002
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0013 0.0001 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.3576 0.0895 0.2419
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0013
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0025 0.0004 0.0004
Onchocerca volvulus 0.0051 0.001 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0008 0.002
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0194 0.0046 0.0124
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Brugia malayi Inositol-1 0.0036 0.0006 0.0017
Toxoplasma gondii heat shock protein 75, putative 0.0026 0.0004 0.0041
Schistosoma mansoni axis inhibition protein axin 0.0017 0.0002 0.0003
Onchocerca volvulus 0.0028 0.0004 0.0144
Echinococcus multilocularis regulator of G protein signaling 3 0.0017 0.0002 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0015 0.0039
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0002 0.0476
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2252 0.0563 0.1521
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.001 0.002
Schistosoma mansoni hypothetical protein 0.0083 0.0018 0.0036
Onchocerca volvulus 0.0051 0.001 0.0352
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0025 0.0004 0.0037
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0057 0.0012 0.0012
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 1.4747 0.37 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0009 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0004 0.0044
Echinococcus granulosus serine protein kinase ATM 0.2252 0.0563 0.0563
Echinococcus granulosus intermediate filament protein 0.0022 0.0003 0.0003
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0002 0.0025
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.317 0.0793 0.2126
Plasmodium falciparum acyl-CoA synthetase 0.0052 0.001 0.0129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0001 0.0003
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0099 0.0022 0.5388
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Plasmodium vivax heat shock protein 90, putative 0.0026 0.0004 0.0046
Echinococcus granulosus cpg binding protein 0.0029 0.0005 0.0005
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0039 0.0007 0.0014
Brugia malayi G-protein coupled receptor 0.0051 0.001 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0286 0.0772
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0024 0.0806
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0033 0.0006 0.0192
Giardia lamblia Kinase, CMGC GSK 0.0046 0.0009 0.0033
Brugia malayi Protein kinase domain containing protein 0.0016 0.0001 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0001 0.0183
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.001 0.001
Echinococcus multilocularis heat shock protein 0.0064 0.0013 0.0013
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0002 0.0005
Schistosoma mansoni amine GPCR 0.0051 0.001 0.002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0051 0.001 0.001
Plasmodium falciparum heat shock protein 90 0.0064 0.0013 0.0165
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0002 0.0046
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0002 0.0002
Echinococcus granulosus hypothetical protein 0.0051 0.001 0.001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0002 0.0005
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0016 0.0001 0.0003
Brugia malayi A-kinase anchor protein 10, precursor 0.0017 0.0002 0.0004
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0088 0.0019 0.0151
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0016 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0122 0.0028 0.0075
Loa Loa (eye worm) hypothetical protein 0.01 0.0022 0.0049
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 1.4747 0.37 1
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0002 0.0004
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.001 0.0022
Entamoeba histolytica phosphoglycerate kinase, putative 0.0172 0.0041 0.0108
Trypanosoma brucei heat shock protein 90, putative 0.0064 0.0013 0.0103
Echinococcus granulosus expressed protein 0.0339 0.0082 0.0082
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0024 0.0806
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.001 0.002
Trypanosoma cruzi heat shock protein 85, putative 0.0051 0.001 0.0026
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0002 0.0005
Leishmania major cAMP-specific phosphodiesterase, putative 0.0016 0.0001 0.0003
Trypanosoma cruzi heat shock protein 85, putative 0.0064 0.0013 0.0034
Echinococcus granulosus sex peptide receptor 0.0051 0.001 0.001
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1149 0.0286 0.0771
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0013 0.0001 0.0004
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0001 0.0006
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0002 0.0067
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0013 0.0001 0.0001
Leishmania major phosphatidylinositol kinase related protein, putative 0.118 0.0293 0.0786
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.001 0.001
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0006 0.0207
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0005
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.5182 0.1298 0.3509
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.317 0.0793 0.2143
Mycobacterium ulcerans putative regulatory protein 0.0041 0.0008 0.1754
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0017 0.0002 0.0004
Plasmodium falciparum GAF domain-related protein, putative 0.0041 0.0008 0.0093
Echinococcus multilocularis casein kinase ii subunit beta 0.0033 0.0006 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.001 0.0321
Schistosoma mansoni amine GPCR 0.0051 0.001 0.002
Echinococcus granulosus neuropeptide receptor 0.0051 0.001 0.001
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Onchocerca volvulus 0.0033 0.0005 0.0187
Plasmodium falciparum thioredoxin reductase 0.0046 0.0009 0.0108
Echinococcus multilocularis axis inhibition protein axin 0.0017 0.0002 0.0002
Schistosoma mansoni 6-phosphofructokinase 0.0099 0.0022 0.0044
Schistosoma mansoni hypothetical protein 0.1258 0.0313 0.0626
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0002 0.0067
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0008 0.0008
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Echinococcus granulosus survival motor neuron protein 1 0.0407 0.0099 0.0099
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0002 0.0002
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0001 0.0013
Schistosoma mansoni thyroid hormone receptor 0.002 0.0002 0.0005
Onchocerca volvulus 0.0022 0.0003 0.0092
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0002 0.0007
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0021 0.0002 0.0007
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0002 0.0005
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0174 0.0041 0.0109
Schistosoma mansoni single-minded 0.0044 0.0008 0.0017
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.3576 0.0895 0.2419
Plasmodium falciparum phosphodiesterase gamma, putative 0.0016 0.0001 0.0013
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.001 0.002
Giardia lamblia Kinase, CMGC CK2 0.0124 0.0029 0.0109
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0022 0.0049
Brugia malayi phosphofructokinase 0.0099 0.0022 0.006
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0006 0.0006
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0165 0.0039 0.0039
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Trichomonas vaginalis phosphofructokinase, putative 0.0099 0.0022 0.0059
Brugia malayi Casein kinase II, alpha chain 0.0124 0.0029 0.0077
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0035 0.0006 0.1388
Schistosoma mansoni neuropeptide receptor 0.0051 0.001 0.002
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0292 0.0071 0.0071
Trypanosoma brucei phosphoglycerate kinase 0.0172 0.0041 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.2408 0.0602 0.1626
Trichomonas vaginalis conserved hypothetical protein 0.1072 0.0266 0.072
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.001 0.002
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0003
Schistosoma mansoni DNA topoisomerase II 0.0013 0.0001 0.0001
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0002 0.0005
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.3588 0.0898 0.2427
Trypanosoma brucei heat shock protein, putative 0.0064 0.0013 0.0103
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) phosphatidylinositol 3 0.3636 0.091 0.2
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.3528 0.0883 0.2386
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0013 0.0028
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 1.9928 0.5001 0.5001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0022 0.006
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0008 0.0008
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0061 0.0012 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.3576 0.0895 0.2419
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0165 0.0039 0.0039
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0027 0.0004 0.0861
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0009 0.0009
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0001 0.0012
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.1149 0.0286 0.3602
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0088 0.0019 0.0052
Trypanosoma cruzi polo-like protein kinase, putative 0.0174 0.0041 0.0109
Schistosoma mansoni amine GPCR 0.0051 0.001 0.002
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0001 0.0003
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0002 0.0004
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0008 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0028 0.0056
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.001 0.0022
Echinococcus multilocularis 0.1149 0.0286 0.0286
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0148 0.0035 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.3528 0.0883 0.2386
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.317 0.0793 0.886
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0016 0.0001 0.0006
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.317 0.0793 0.2143
Brugia malayi cytochrome P450 0.0035 0.0006 0.0016
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.001 0.001
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Schistosoma mansoni aryl hydrocarbon receptor 0.0044 0.0008 0.0017
Trypanosoma brucei heat shock protein, putative 0.0064 0.0013 0.0103
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.1149 0.0286 0.3192
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.3636 0.091 0.7326
Brugia malayi MH2 domain containing protein 0.0121 0.0028 0.0075
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0099 0.0022 0.0767
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0004 0.0046
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.001 0.0022
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.317 0.0793 0.0793
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Trypanosoma brucei heat shock protein 84, putative 0.0026 0.0004 0.0027
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.1149 0.0286 0.0572
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0006 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.3576 0.0895 0.2419
Loa Loa (eye worm) hypoxia-induced factor 1 0.0137 0.0032 0.0069
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.3584 0.0897 0.0897
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 1.4747 0.37 1
Echinococcus granulosus endoplasmin 0.0051 0.001 0.001
Brugia malayi nuclear receptor NHR-88 0.002 0.0002 0.0006
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0 0.0001
Brugia malayi CXXC zinc finger family protein 0.0028 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0025 0.0004 0.0008
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0027 0.0004 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0001 0.0002
Toxoplasma gondii hypothetical protein 0.0041 0.0008 0.0082
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0002 0.0476
Echinococcus granulosus single minded 2 0.0039 0.0007 0.0007
Onchocerca volvulus 0.0083 0.0018 0.0628
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.4959 0.1242 0.3358
Loa Loa (eye worm) phosphatidylinositol kinase 0.1149 0.0286 0.0628
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.001 0.0022
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0033 0.0006 0.0192
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0016 0.0001 0.0002
Leishmania major protein kinase, putative 0.0023 0.0003 0.0008
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0016 0.0001 0.0002
Schistosoma mansoni phosphatidylinositol 4-kinase 0.1149 0.0286 0.0572
Loa Loa (eye worm) hypothetical protein 0.0031 0.0005 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0002 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.001 0.001
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0001 0.0002
Brugia malayi regulator of G-protein signaling rgs-7 0.0017 0.0002 0.0004
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0016 0.0001 0.0001
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.5913 0.1482 0.4005
Trichomonas vaginalis conserved hypothetical protein 0.1258 0.0313 0.0846
Echinococcus granulosus death domain containing protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0008 0.0017
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0016 0.0001 0.0003
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.001 0.001
Leishmania major casein kinase II, putative 0.0124 0.0029 0.0076
Loa Loa (eye worm) hypothetical protein 0.007 0.0015 0.0033
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0012 0.0031
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.001 0.0022
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.3584 0.0897 0.1794
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.001 0.001
Schistosoma mansoni biogenic amine receptor 0.0051 0.001 0.002
Leishmania major hypothetical protein, conserved 0.0016 0.0001 0.0003
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0033 0.0006 0.0041
Schistosoma mansoni neuropeptide receptor 0.0051 0.001 0.002
Schistosoma mansoni kinase 0.009 0.002 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.348 0.0871 0.2354
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0099 0.0022 0.0058
Loa Loa (eye worm) phosphofructokinase 0.0099 0.0022 0.0048
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0082 0.0018 0.0039
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.001 0.0352
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.001 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0041 0.0082
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Toxoplasma gondii DNA topoisomerase 2, putative 0.0013 0.0001 0.0004
Schistosoma mansoni hypothetical protein 0.0031 0.0005 0.001
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0013 0.0025
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.001 0.0028
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0148 0.0035 0.0093
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0002 0.0067
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0002 0.0005
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0016 0.0001 0.0006
Leishmania major hypothetical protein, unknown function 0.1149 0.0286 0.0766
Echinococcus granulosus fmrfamide receptor 0.0051 0.001 0.001
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.001 0.001
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0026 0.0004 0.0128
Trypanosoma brucei heat shock protein, putative 0.0064 0.0013 0.0103
Brugia malayi AMP-binding enzyme family protein 0.007 0.0015 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.001 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.2516 0.0629 0.17
Toxoplasma gondii non-specific serine/threonine protein kinase 0.2408 0.0602 0.6722
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0012 0.0025
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0194 0.0046 0.0092
Trichomonas vaginalis DNA helicase recq1, putative 0.0017 0.0002 0.0004
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0013 0.0001 0.0013
Brugia malayi intermediate filament protein 0.0022 0.0003 0.0008
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0124 0.0029 0.0076
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0017 0.0002 0.0002
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.2244 0.0561 0.1514
Echinococcus multilocularis lamin dm0 0.0022 0.0003 0.0003
Onchocerca volvulus 0.0022 0.0003 0.0092
Leishmania major phosphatidylinositol 3-related kinase, putative 0.3502 0.0877 0.235
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0002 0.0005
Plasmodium falciparum casein kinase 2, alpha subunit 0.0124 0.0029 0.0357
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0012 0.0031
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0046 0.0009 0.0009
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.1149 0.0286 0.0286
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.001 0.0022
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0002 0.0476
Brugia malayi hypoxia-induced factor 1 0.0137 0.0032 0.0085
Plasmodium vivax hypothetical protein 0.1149 0.0286 0.3602
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.007 0.0015 0.358
Echinococcus multilocularis protein kinase shaggy 0.0046 0.0009 0.0009
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0172 0.0041 0.0108
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0006 0.0016
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0011 0.0118
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0006 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0004 0.0007
Onchocerca volvulus 0.0051 0.001 0.0352
Schistosoma mansoni neuropeptide receptor 0.0051 0.001 0.002
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0046 0.0009 0.002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0026 0.0908
Leishmania major phosphatidylinositol kinase, putative 0.1149 0.0286 0.0766
Trichomonas vaginalis PIKK family atypical protein kinase 0.2318 0.0579 0.1565
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0035 0.0006 0.0194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0002 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.3576 0.0895 0.2419
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0035 0.0006 0.0194
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.3636 0.091 0.2459
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0017 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0002 0.0006
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0172 0.0041 0.1401
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0002 0.0006
Loa Loa (eye worm) glutathione reductase 0.0046 0.0009 0.0019
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0027 0.0004 0.0048
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0002 0.0067
Trichomonas vaginalis heat shock protein, putative 0.0051 0.001 0.0027
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0002 0.0005
Loa Loa (eye worm) intermediate filament protein 0.0022 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0035 0.0006 0.1388
Trichomonas vaginalis PIKK family atypical protein kinase 0.3588 0.0898 0.2427
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0001 0.0001
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Leishmania major phosphoglycerate kinase B, cytosolic 0.0172 0.0041 0.0108
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.1149 0.0286 0.0771
Echinococcus multilocularis neuropeptide receptor 0.0051 0.001 0.001
Leishmania major phosphoglycerate kinase C, glycosomal 0.0172 0.0041 0.0108
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0002 0.0005
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Loa Loa (eye worm) RNA binding protein 0.0061 0.0013 0.0028
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.001 0.001
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Brugia malayi AMP-binding enzyme family protein 0.007 0.0015 0.004
Brugia malayi Serotonin receptor 0.0051 0.001 0.0028
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0088 0.0019 0.0052
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0035 0.0006 0.1388
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0005
Brugia malayi kinase, mitochondrial precursor 0.0013 0.0001 0.0001
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.001 0.001
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0035 0.0006 0.0194
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0002 0.0006
Plasmodium falciparum phosphoglycerate kinase 0.0172 0.0041 0.0508
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Brugia malayi Death domain containing protein 0.0013 0.0001 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0002 0.0007
Schistosoma mansoni axis inhibition protein axin 0.0017 0.0002 0.0003
Entamoeba histolytica hypothetical protein 0.0036 0.0006 0.0016
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0001 0.0003
Mycobacterium ulcerans heat shock protein 90 0.0051 0.001 0.2371
Trichomonas vaginalis PIKK family atypical protein kinase 0.2318 0.0579 0.1565
Loa Loa (eye worm) hypothetical protein 0.0095 0.0021 0.0047
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0051 0.001 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0002 0.0476
Trypanosoma cruzi heat shock protein 85, putative 0.0064 0.0013 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0006 0.0012
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0115 0.0026 0.0895
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0004 0.001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0004
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.001 0.001
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.3584 0.0897 0.2423
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0016 0.0001 0.0001
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0067 0.0014 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0013 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0013 0.0025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0052 0.001 0.0023
Trypanosoma cruzi heat shock protein 85, putative 0.0064 0.0013 0.0034
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.2456 0.0614 0.4939
Trichomonas vaginalis PIKK family atypical protein kinase 0.3636 0.091 0.246
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.3502 0.0877 0.7054
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0016 0.0001 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0051 0.001 0.001
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0001 0.0013
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0174 0.0041 0.0041
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0001 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0009 0.0022
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.001 0.002
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0002 0.0332
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0005
Brugia malayi hypothetical protein 0.0017 0.0002 0.0004
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0172 0.0041 1
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0033 0.0006 0.0014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.001 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0107 0.0024 0.0053
Brugia malayi Dopamine receptor protein 2 0.0051 0.001 0.0028
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Leishmania major hypothetical protein, conserved 0.0013 0.0001 0.0001
Schistosoma mansoni cpg binding protein 0.0029 0.0005 0.0009
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0031 0.0005 0.001
Plasmodium vivax 6-phosphofructokinase, putative 0.0027 0.0004 0.0047
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0067 0.0014 0.0031
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0002 0.0006
Echinococcus granulosus g-protein coupled receptor 0.0051 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0052 0.001 0.0023
Brugia malayi hypothetical protein 0.0026 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0016 0.0001 0.0002
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0006 0.0068
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0016 0.0001 0.0013
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0061 0.0013 0.0032
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0002 0.0015
Onchocerca volvulus 0.0051 0.001 0.0352
Entamoeba histolytica hypothetical protein 0.0017 0.0002 0.0003
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.1197 0.0298 0.0805
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.2939 0.0735 0.2868
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.1149 0.0286 0.0286
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.001 0.0321
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.001 0.001
Onchocerca volvulus 0.0051 0.001 0.0352
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0002 0.0075
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0001 0.0001
Schistosoma mansoni inositol monophosphatase 0.0036 0.0006 0.0013
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Echinococcus granulosus cyclin dependent kinase 19 0.0122 0.0028 0.0028
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.3528 0.0883 0.2386
Echinococcus multilocularis survival motor neuron protein 1 0.0407 0.0099 0.0099
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.001 0.001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0022 0.006
Mycobacterium leprae Probable two component sensor kinase MprB 0.0013 0.0001 0.0013
Entamoeba histolytica hypothetical protein 0.2252 0.0563 0.152
Trichomonas vaginalis PIKK family atypical protein kinase 0.3502 0.0877 0.2369
Brugia malayi Phosphoglycerate kinase 0.0063 0.0013 0.0036
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0001 0.0001
Echinococcus granulosus lamin dm0 0.0022 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0002 0.0004
Schistosoma mansoni hypothetical protein 0.0031 0.0005 0.001
Brugia malayi glutathione reductase 0.0046 0.0009 0.0024
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 1.2003 0.3011 0.8138
Brugia malayi Egg laying defective protein 4 0.0012 0 0.0001
Trypanosoma brucei phosphoglycerate kinase 0.0063 0.0013 0.0102
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0011 0.0029
Loa Loa (eye worm) hypothetical protein 0.0407 0.0099 0.0218
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.2222 0.0555 0.122
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.001 0.2469
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1149 0.0286 0.0773
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0005 0.0168
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 1.9928 0.5001 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0023 0.0003 0.0003
Brugia malayi TAR-binding protein 0.0061 0.0013 0.0034
Onchocerca volvulus 0.0021 0.0002 0.008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0002 0.0004
Loa Loa (eye worm) follicle stimulating hormone receptor 0.026 0.0063 0.0138
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0002 0.0004
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0035 0.0006 0.1388
Brugia malayi Pre-SET motif family protein 0.017 0.004 0.0108
Schistosoma mansoni hypothetical protein 0.0039 0.0007 0.0014
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0004 0.0046
Trypanosoma cruzi heat shock protein 90, putative 0.0038 0.0007 0.0017
Onchocerca volvulus Netrin receptor homolog 0.0013 0.0001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.0005
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0001 0.0006
Brugia malayi Protein kinase domain containing protein 0.0292 0.0071 0.0191
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0088 0.0019 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0002 0.0006
Echinococcus multilocularis expressed conserved protein 0.0155 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0162 0.0038 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.001 0.002
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.001 0.001
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.001 0.001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0001 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0029 0.0077
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.001 0.0028
Brugia malayi FAT domain containing protein 0.1258 0.0313 0.0846
Echinococcus multilocularis g protein coupled receptor 0.0051 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0015 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.1149 0.0286 0.0772
Giardia lamblia Phosphatidylinositol 4-kinase 0.1149 0.0286 0.1114
Loa Loa (eye worm) hypothetical protein 0.0058 0.0012 0.0026
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.1149 0.0286 0.3192
Onchocerca volvulus 0.0034 0.0006 0.0199
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0035 0.0006 0.0194
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0002 0.0006
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0013 0.0034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0002 0.0075
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0002 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.001 0.001
Leishmania major cytochrome p450-like protein 0.0035 0.0006 0.0016
Entamoeba histolytica hypothetical protein 0.1149 0.0286 0.0772
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0035 0.0006 0.0194
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.1258 0.0313 0.0313
Brugia malayi PXA domain containing protein 0.0019 0.0002 0.0005
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Leishmania major hypothetical protein, conserved 1.4865 0.373 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0002 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.2252 0.0563 0.152
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0016 0.0001 0.0002
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0001 0.0001
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Schistosoma mansoni opsin-like receptor 0.0051 0.001 0.002
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0016 0.0001 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0002 0.0007
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0003
Plasmodium vivax acyl-CoA synthetase, putative 0.0052 0.001 0.0128
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.001 0.001
Leishmania major heat shock protein, putative 0.0026 0.0004 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0019 0.0052
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0016 0.0001 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0035 0.0006 0.0194
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.001 0.002
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0002 0.0067
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Toxoplasma gondii exonuclease III APE 0.0018 0.0002 0.0019
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0148 0.0035 0.0076
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0026 0.0908
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0017 0.0002 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0035 0.0006 0.0194
Loa Loa (eye worm) phosphatidylinositol 3 0.3502 0.0877 0.1926
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0033 0.0006 0.0014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0002 0.0002
Brugia malayi Dopamine receptor protein 1 0.0051 0.001 0.0028
Schistosoma mansoni heat shock protein 0.0064 0.0013 0.0027
Echinococcus multilocularis fmrfamide receptor 0.0051 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0002 0.0005
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0001 0.0002
Schistosoma mansoni 6-phosphofructokinase 0.0099 0.0022 0.0044
Mycobacterium ulcerans phosphoglycerate kinase 0.0172 0.0041 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.3584 0.0897 0.2425
Echinococcus granulosus tar DNA binding protein 0.0061 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0051 0.001 0.002
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0002 0.0476
Brugia malayi G-protein coupled receptor 0.0051 0.001 0.0028
Echinococcus multilocularis allatostatin A receptor 0.0051 0.001 0.001
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0035 0.0006 0.1388
Plasmodium vivax DNA topoisomerase II, putative 0.0013 0.0001 0.0004
Brugia malayi Dopamine receptor 0.0051 0.001 0.0028
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0002 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0002 0.0005
Echinococcus granulosus orexin receptor type 2 0.0051 0.001 0.001
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0088 0.0019 0.0052
Toxoplasma gondii FATC domain-containing protein 0.2252 0.0563 0.6285
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0022 0.0045
Loa Loa (eye worm) hypothetical protein 0.0052 0.001 0.0023
Plasmodium falciparum glycogen synthase kinase 3 0.0046 0.0009 0.011
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0006
Schistosoma mansoni patched 1 0.0041 0.0008 0.0015
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0017 0.0002 0.0004
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0035 0.0006 0.1388
Trichomonas vaginalis PIKK family atypical protein kinase 0.3636 0.091 0.246
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0033 0.0006 0.0014
Mycobacterium tuberculosis Conserved hypothetical protein 0.0061 0.0013 0.0421
Echinococcus granulosus g protein coupled receptor 0.0051 0.001 0.001
Echinococcus granulosus nuclear factor of activated T cells 5 0.0067 0.0014 0.0014
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.1149 0.0286 0.0286
Echinococcus granulosus casein kinase ii subunit alpha 0.0124 0.0029 0.0029
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0035 0.0006 0.0194
Schistosoma mansoni amine GPCR 0.0051 0.001 0.002
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0013 0.0028
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0035 0.0006 0.1388
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0016 0.0001 0.0002
Brugia malayi neuropeptide F receptor 0.0051 0.001 0.0028
Echinococcus multilocularis regulator of G protein signaling 3 0.0017 0.0002 0.0002
Brugia malayi RE15519p 0.0051 0.001 0.0028
Schistosoma mansoni z-protein (S1r protein) 0.0017 0.0002 0.0003
Plasmodium falciparum thioredoxin reductase 0.0016 0.0001 0.0013
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0027 0.0004 0.0861
Brugia malayi heat shock protein 90 0.0064 0.0013 0.0036
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.001 0.001
Schistosoma mansoni phosphatidylinositol 4-kinase 0.317 0.0793 0.1586
Trichomonas vaginalis CAMK family protein kinase 0.0087 0.0019 0.0052
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0174 0.0041 0.009
Schistosoma mansoni serine/threonine protein kinase 0.0292 0.0071 0.0141
Plasmodium falciparum endoplasmin, putative 0.0039 0.0007 0.0087
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0002 0.0067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0002 0.0002
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0002 0.0002
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0008 0.0008
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0002 0.0006
Schistosoma mansoni netrin receptor unc5 0.0013 0.0001 0.0001
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.5 0.1253 0.3385
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0001 0.0002
Brugia malayi Bloom's syndrome protein homolog 0.0017 0.0002 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.3636 0.091 0.244
Schistosoma mansoni hypothetical protein 0.0051 0.001 0.002
Echinococcus multilocularis protein patched 0.0041 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0001 0.0183
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0001 0.0001
Brugia malayi Regulator of G protein signaling domain containing protein 0.0017 0.0002 0.0004
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0033 0.0006 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.001 0.001
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0035 0.0006 0.1388
Trichomonas vaginalis PIKK family atypical protein kinase 0.348 0.0871 0.2354
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.1246 0.031 0.2492
Echinococcus granulosus neuropeptide receptor 0.0051 0.001 0.001
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0001 0.0006
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0016 0.0001 0.0001
Brugia malayi AKH receptor 0.0051 0.001 0.0028
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0002 0.0332
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.001 0.001
Brugia malayi hypothetical protein 0.0016 0.0001 0.0004
Onchocerca volvulus 0.0051 0.001 0.0352
Echinococcus multilocularis regulator of G protein signaling 7 0.0017 0.0002 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0028 0.0061
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0035 0.0006 0.1388
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0016 0.0001 0.0002
Loa Loa (eye worm) PDE1B protein 0.0016 0.0001 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.001 0.001
Echinococcus granulosus dnaJ subfamily B 0.0396 0.0097 0.0097
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0009 0.0289
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0002 0.0002
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.1149 0.0286 0.0772
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0075 0.0016 0.0042
Echinococcus multilocularis heat shock protein 90 0.0051 0.001 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0015 0.358
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0001 0.0002
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0015 0.0001 0.0011
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0002 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Brugia malayi Hsp90 protein 0.0026 0.0004 0.001
Leishmania major phosphatidylinositol 3-kinase, putative 0.348 0.0871 0.2335
Loa Loa (eye worm) hypothetical protein 0.0099 0.0022 0.0049
Schistosoma mansoni ap endonuclease 0.0018 0.0002 0.0004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0013 0.0001 0.0001
Trypanosoma cruzi heat shock protein 90, putative 0.0064 0.0013 0.0034
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0005 0.0014
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.4959 0.1242 0.3357
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0002 0.0005
Echinococcus multilocularis cyclin dependent kinase 19 0.0122 0.0028 0.0028
Trypanosoma cruzi Heat shock protein 83, putative 0.0064 0.0013 0.0034
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.317 0.0793 0.2143
Brugia malayi GnHR receptor homolog 0.0051 0.001 0.0028
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0002 0.0003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0003 0.0029
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0292 0.0071 0.0071
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.317 0.0793 0.1586
Brugia malayi hypothetical protein 0.0082 0.0018 0.0049
Brugia malayi Pre-SET motif family protein 0.0025 0.0004 0.001
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.001 0.002
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0016 0.0001 0.0003
Trichomonas vaginalis phosphatidylinositol kinase, putative 1.4747 0.37 1
Brugia malayi 6-phosphofructokinase 0.0099 0.0022 0.006
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0002 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0002 0.0476
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0016 0.0001 0.0001
Brugia malayi hypothetical protein 0.0017 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0006
Brugia malayi putative neuropeptide receptor 0.0051 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Plasmodium vivax SET domain protein, putative 0.0025 0.0004 0.0042
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Brugia malayi neuropeptide F receptor 0.0051 0.001 0.0028
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.001 0.001
Plasmodium vivax glycogen synthase kinase 3, putative 0.0046 0.0009 0.011
Loa Loa (eye worm) TOPoisomerase family member 0.0013 0.0001 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0002 0.0005
Plasmodium falciparum glutathione reductase 0.0016 0.0001 0.0013
Echinococcus multilocularis 0.0035 0.0006 0.0006
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0061 0.0013 0.0032
Plasmodium falciparum phosphatidylinositol 4-kinase 0.1149 0.0286 0.3603
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0052 0.001 0.2469
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Entamoeba histolytica acyl-coA synthetase, putative 0.007 0.0015 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0001 0.0002
Brugia malayi Cytochrome P450 family protein 0.0056 0.0011 0.003
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0001 0.0003
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.001 0.001
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0046 0.0009 0.0018
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0015 0.0039
Brugia malayi Cytochrome P450 family protein 0.0056 0.0011 0.003
Echinococcus multilocularis Ankyrin 0.0013 0.0001 0.0001
Brugia malayi Uncoordinated protein 44 0.0013 0.0001 0.0002
Onchocerca volvulus 0.0082 0.0018 0.0622
Trichomonas vaginalis phosphofructokinase, putative 0.0099 0.0022 0.0059
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.317 0.0793 0.886
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0013 0.0001 0.0001
Schistosoma mansoni intermediate filament proteins 0.0022 0.0003 0.0006
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0002 0.0021
Echinococcus granulosus somatostatin receptor 0.0051 0.001 0.001
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.4959 0.1242 1
Echinococcus multilocularis Regulator of G protein signaling 20 0.0017 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.3528 0.0883 0.2386
Trypanosoma cruzi target of rapamycin kinase 3 0.3588 0.0898 0.2427
Entamoeba histolytica hypothetical protein 0.0036 0.0006 0.0016
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0035 0.0006 0.1388
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0013 0.0025
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0002 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0002 0.0006
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0051 0.001 0.001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.3636 0.091 0.2459
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0148 0.0035 0.0093
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.3636 0.091 0.182
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Entamoeba histolytica protein kinase domain containing protein 0.0046 0.0009 0.0023
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0051 0.001 0.0332
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.001 0.002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.001 0.001
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Trichomonas vaginalis heat shock protein, putative 0.0051 0.001 0.0027
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0033 0.0006 0.0014
Onchocerca volvulus 0.01 0.0022 0.0775
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0046 0.0009 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0002 0.0006
Entamoeba histolytica serine/threonine protein kinase, putative 0.0174 0.0041 0.011
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2222 0.0555 0.15
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0002 0.0005
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0088 0.0019 0.0052
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.1149 0.0286 0.3192
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0036 0.0006 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0002 0.0005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0003 0.0029
Plasmodium falciparum DNA gyrase subunit B 0.0013 0.0001 0.0004
Plasmodium vivax heat shock protein 86, putative 0.0064 0.0013 0.0165
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0005 0.0014
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0035 0.0006 0.1388
Loa Loa (eye worm) oxidoreductase 0.0021 0.0002 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0035 0.0006 0.0194
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0035 0.0006 0.0194
Schistosoma mansoni coup transcription factor 0.002 0.0002 0.0005
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0004 0.0025
Brugia malayi intracellular kinase 0.0046 0.0009 0.0024
Brugia malayi larval opioid receptor 0.0051 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0005
Echinococcus granulosus allatostatin A receptor 0.0051 0.001 0.001
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0015 0.0039
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0013 0.0001 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0029 0.0077
Echinococcus granulosus heat shock protein 0.0064 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.1102 0.0274 0.0602
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0054 0.0011 0.036
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0162 0.0038 0.0084
Loa Loa (eye worm) hypothetical protein 0.0052 0.001 0.0023
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0079 0.0017 0.0034
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 1.4747 0.37 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0005
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.001 0.002
Giardia lamblia hypothetical protein 0.0016 0.0001 0.0003
Onchocerca volvulus 0.0051 0.001 0.0352
Trichomonas vaginalis PIKK family atypical protein kinase 0.2378 0.0594 0.1606
Loa Loa (eye worm) hypothetical protein 0.0082 0.0018 0.0039
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0088 0.0019 0.0051
Schistosoma mansoni thyroid hormone receptor 0.002 0.0002 0.0005
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0052 0.001 0.0346
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0006 0.0016
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0025 0.0004 0.0004
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0292 0.0071 0.0155
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Echinococcus multilocularis Zinc finger, PHD finger 0.317 0.0793 0.0793
Schistosoma mansoni opsin-like receptor 0.0051 0.001 0.002
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0002 0.0005
Brugia malayi 6-phosphofructokinase 0.0099 0.0022 0.006
Echinococcus multilocularis serotonin receptor 0.0051 0.001 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0011 0.0029
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0024 0.0806
Schistosoma mansoni endoplasmin 0.0064 0.0013 0.0027
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0006 0.0016
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.3809 0.0954 0.2577
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.001 0.002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.001 0.0022
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.118 0.0293 0.0792
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0009 0.0019
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0002 0.0067
Onchocerca volvulus 0.0051 0.001 0.0352
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0002 0.0332
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0016 0.0001 0.0003
Schistosoma mansoni heat shock protein 0.0064 0.0013 0.0027
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0011 0.0086
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0035 0.0006 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0041 0.011
Echinococcus multilocularis endoplasmin 0.0051 0.001 0.001
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0016 0.0001 0.0002
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0033 0.0006 0.0014
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0013
Trichomonas vaginalis receptor histidine kinase, putative 0.0013 0.0001 0.0001
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.1149 0.0286 0.3602
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0035 0.0006 0.0194
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0 0.0001
Giardia lamblia Heat shock protein HSP 90-alpha 0.0064 0.0013 0.005
Leishmania major mitochondrial DNA topoisomerase II 0.0013 0.0001 0.0001
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.001 0.001
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0786 0.0195 0.0195
Brugia malayi hypothetical protein 0.0036 0.0006 0.0017
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0124 0.0029 0.0063
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0016 0.0001 0.0003
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0001 0.0002
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0032 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0002 0.0006
Leishmania major trypanothione reductase 0.0046 0.0009 0.0023
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Trichomonas vaginalis phosphofructokinase, putative 0.0099 0.0022 0.0059
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0099 0.0022 0.0755
Loa Loa (eye worm) hypothetical protein 0.0646 0.016 0.0351
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0026 0.0908
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0005 0.0005
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0002 0.0002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.001 0.001
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0013 0.0001 0.0004
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 1.4747 0.37 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0067 0.0014 0.0014
Giardia lamblia Kinase, PLK 0.0174 0.0041 0.0158
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Brugia malayi bHLH-PAS transcription factor 0.0033 0.0005 0.0015
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0073 0.0016 0.0031
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0009 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0001 0.0003
Onchocerca volvulus 0.002 0.0002 0.0075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0001 0.0002
Brugia malayi PAS domain containing protein 0.0044 0.0008 0.0023
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0061 0.0013 0.0097
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Schistosoma mansoni biogenic amine receptor 0.0051 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0029 0.0077
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0002 0.0006
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.0013 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0001 0.0003
Toxoplasma gondii hypothetical protein 0.0041 0.0008 0.0082
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.3636 0.091 0.091
Trichomonas vaginalis endoplasmin, putative 0.0039 0.0007 0.0019
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.2252 0.0563 0.1125
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0001 0.0002
Schistosoma mansoni neuropeptide receptor 0.0051 0.001 0.002
Giardia lamblia GTOR 0.3636 0.091 0.3552
Echinococcus multilocularis somatostatin receptor 0.0051 0.001 0.001
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0002 0.0476
Giardia lamblia Casein kinase II beta chain 0.0033 0.0006 0.002
Schistosoma mansoni cytochrome P450 0.0035 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0041 0.0008 0.0017
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0035 0.0006 0.0194
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0002 0.0005
Loa Loa (eye worm) gastrulation defective protein 1 0.0118 0.0027 0.0059
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.317 0.0793 0.6383
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.001 0.0028
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Mycobacterium leprae Probable two-component sensor kinase 0.0013 0.0001 0.0013
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0006 0.0015
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0015 0.0039
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0088 0.0019 0.0151
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.007 0.0015 0.358
Onchocerca volvulus 0.0046 0.0009 0.0306
Trypanosoma cruzi casein kinase II, putative 0.0124 0.0029 0.0076
Echinococcus granulosus protein kinase shaggy 0.0046 0.0009 0.0009
Mycobacterium leprae putative cytochrome p450 0.0035 0.0006 0.0207
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0041 0.011
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.3636 0.091 0.2459
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0051 0.001 0.002
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0021 0.0002 0.008
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0016 0.0001 0.0003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.3588 0.0898 0.2427
Brugia malayi PXA domain containing protein 0.0019 0.0002 0.0005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0016 0.0001 0.0012
Echinococcus multilocularis neuropeptide receptor A26 0.0051 0.001 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.001 0.0321
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0002 0.0006
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0002 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0015 0.358
Schistosoma mansoni amine GPCR 0.0051 0.001 0.002
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0088 0.0019 0.0052
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0029 0.0077
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Brugia malayi hypothetical protein 0.0407 0.0099 0.0269
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0035 0.0006 0.1388
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0027 0.0004 0.0042
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0021 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0002 0.0476
Echinococcus multilocularis phosphoglycerate kinase 1 0.0172 0.0041 0.0041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0002 0.0006
Giardia lamblia Heat shock protein HSP 90-alpha 0.0051 0.001 0.0037
Trichomonas vaginalis CMGC family protein kinase 0.0046 0.0009 0.0024
Schistosoma mansoni survival motor neuron protein 0.0083 0.0018 0.0036
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0001 0.0006
Loa Loa (eye worm) Csnk2b protein 0.0033 0.0006 0.0012
Echinococcus multilocularis tumor protein p63 0.0681 0.0168 0.0168
Plasmodium vivax unspecified product 0.0124 0.0029 0.0357
Mycobacterium ulcerans hypothetical protein 0.007 0.0015 0.358
Brugia malayi ORL1-like opioid receptor 0.0051 0.001 0.0028
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0003
Echinococcus granulosus expressed conserved protein 0.009 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0148 0.0035 0.0093
Trypanosoma brucei heat shock protein, putative 0.0064 0.0013 0.0103
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0006 0.0006
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0073 0.0016 0.0031
Toxoplasma gondii Hsp90 domain-containing protein 0.0026 0.0004 0.0041
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.1149 0.0286 0.0771
Entamoeba histolytica hypothetical protein 1.2957 0.3251 0.8786
Trichomonas vaginalis PIKK family atypical protein kinase 0.2222 0.0555 0.15
Loa Loa (eye worm) hypothetical protein 0.007 0.0015 0.0033
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0088 0.0019 0.0039
Echinococcus multilocularis serine protein kinase ATM 0.2252 0.0563 0.0563
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0001 0.0183
Echinococcus granulosus casein kinase ii subunit beta 0.0033 0.0006 0.0006
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.317 0.0793 0.2143
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0013 0.0001 0.0004
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.001 0.002
Schistosoma mansoni protein kinase 0.0124 0.0029 0.0057
Trichomonas vaginalis receptor histidine kinase, putative 0.0013 0.0001 0.0001
Leishmania major heat shock protein 83-1 0.0064 0.0013 0.0035
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0006 0.1437
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0002 0.0005
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.3636 0.091 0.244
Trichomonas vaginalis PIKK family atypical protein kinase 0.3576 0.0895 0.2419
Onchocerca volvulus 0.0051 0.001 0.0352
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.7746 0.1942 0.5249
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.1149 0.0286 0.0286
Schistosoma mansoni hypothetical protein 0.0039 0.0007 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0001 0.0002
Trichomonas vaginalis casein kinase II beta chain, putative 0.0033 0.0006 0.0015
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0172 0.0041 0.0451
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.007 0.0015 0.0502
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0001 0.0002
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.317 0.0793 0.2143
Echinococcus granulosus Ankyrin 0.0013 0.0001 0.0001
Trypanosoma brucei Heat shock protein 83, putative 0.0064 0.0013 0.0103
Toxoplasma gondii target of rapamycin (TOR), putative 0.3576 0.0895 1
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.317 0.0793 0.2144
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0011 0.0025
Echinococcus granulosus phosphoglycerate kinase 1 0.0172 0.0041 0.0041
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0172 0.0041 0.0109
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0026 0.0004 0.0004
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0013 0.0001 0.0001
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0016 0.0001 0.0001
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.3584 0.0897 0.0897
Brugia malayi hypothetical protein 0.0051 0.001 0.0028
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0014 0.0038
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0015 0.0514
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0001 0.0013
Trypanosoma brucei polo-like protein kinase 0.0174 0.0041 0.0326
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0046 0.0009 0.002
Onchocerca volvulus 0.0051 0.001 0.0352
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.1149 0.0286 0.2298
Echinococcus multilocularis g protein coupled receptor 0.0051 0.001 0.001
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0009 0.0108
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0006 0.0017
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0016 0.0001 0.0002
Echinococcus multilocularis geminin 0.0329 0.008 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.001 0.001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.001 0.001
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0002 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0016 0.0001 0.0001
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0002 0.0476
Trichomonas vaginalis phosphofructokinase, putative 0.0099 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0002 0.0006
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0004 0.0044
Giardia lamblia Phosphoglycerate kinase 0.0172 0.0041 0.0156
Echinococcus multilocularis g protein coupled receptor 0.0051 0.001 0.001
Echinococcus granulosus bloom syndrome protein 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0035 0.0006 0.0194
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0002 0.0067
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.1149 0.0286 0.0572
Schistosoma mansoni voltage-gated potassium channel 0.0073 0.0016 0.0031
Trypanosoma brucei protein kinase, putative 0.0046 0.0009 0.0067
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0002 0.0007
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0292 0.0071 0.2464
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 1.3597 0.3411 0.922
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0004 0.001
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0051 0.001 0.0352
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.001 0.002
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.001 0.0352
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0002 0.0005
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0013 0.0001 0.0001
Echinococcus multilocularis musashi 0.0022 0.0003 0.0003
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0027 0.0004 0.001
Schistosoma mansoni hypothetical protein 0.0329 0.008 0.016
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.2252 0.0563 0.4527
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0033 0.0006 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0001 0.0003
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0002 0.0002
Trichomonas vaginalis heat shock protein, putative 0.0064 0.0013 0.0035
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.0097 0.0097
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0013 0.0001 0.0004
Entamoeba histolytica hypothetical protein 0.0017 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.001 0.0022
Entamoeba histolytica phosphofructokinase, putative 0.0099 0.0022 0.0058
Loa Loa (eye worm) phosphatidylinositol 3 0.3809 0.0954 0.2095
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0002 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.348 0.0871 0.2354

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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