Detailed information for compound 699143

Basic information

Technical information
  • TDR Targets ID: 699143
  • Name: 4-fluoro-N-[3-(2-methyl-4-oxoquinazolin-3-yl) phenyl]-3-(trifluoromethyl)benzenesulfonamide
  • MW: 477.431 | Formula: C22H15F4N3O3S
  • H donors: 1 H acceptors: 3 LogP: 3.94 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1C(F)(F)F)S(=O)(=O)Nc1cccc(c1)n1c(C)nc2c(c1=O)cccc2
  • InChi: 1S/C22H15F4N3O3S/c1-13-27-20-8-3-2-7-17(20)21(30)29(13)15-6-4-5-14(11-15)28-33(31,32)16-9-10-19(23)18(12-16)22(24,25)26/h2-12,28H,1H3
  • InChiKey: SIKMMMUBPPMKDD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-fluoro-N-[3-(2-methyl-4-oxo-quinazolin-3-yl)phenyl]-3-(trifluoromethyl)benzenesulfonamide
  • 4-fluoro-N-[3-(2-methyl-4-oxo-3-quinazolinyl)phenyl]-3-(trifluoromethyl)benzenesulfonamide
  • 4-fluoro-N-[3-(4-keto-2-methyl-quinazolin-3-yl)phenyl]-3-(trifluoromethyl)benzenesulfonamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.1703 0.1702
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0004
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0234 0.0232
Loa Loa (eye worm) glutathione reductase 0.0095 0.1066 0.1066
Loa Loa (eye worm) hypothetical protein 0.0136 0.1612 0.1612
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0569 0.0936
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0016 0.0003 0.0002
Loa Loa (eye worm) cytochrome P450 0.0021 0.0076 0.0076
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0204 0.252 0.4153
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0003 0.0001
Loa Loa (eye worm) fibroinase 0.0017 0.0025 0.0025
Onchocerca volvulus 0.0033 0.0234 0.0529
Echinococcus granulosus geminin 0.0167 0.2026 0.2025
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0271 0.0819
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0003 0.0005
Brugia malayi cytochrome P450 0.0021 0.0076 0.0075
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0025 0.0247
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0141 0.167 0.2751
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0076 0.0245
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0027 0.015 0.0488
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Trypanosoma cruzi metacaspase, putative 0.0178 0.2167 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.1245
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0016 0.0003 0.0005
Schistosoma mansoni caspase-3 (C14 family) 0.047 0.6066 1
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0076 0.0509
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0778 0.3585
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0107
Loa Loa (eye worm) oxidoreductase 0.0016 0.0003 0.0003
Echinococcus multilocularis caspase 0.047 0.6066 0.6065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0067
Echinococcus multilocularis thioredoxin glutathione reductase 0.0095 0.1066 0.1064
Brugia malayi Dehydrogenases, short chain protein 30 0.0016 0.0003 0.0001
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0271 0.0819
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0003 0.0005
Brugia malayi Cytochrome P450 family protein 0.0078 0.0835 0.0834
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0235 0.108
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0016 0.0003 0.0005
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0025 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0067
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0025 0.0107
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Echinococcus granulosus expressed protein 0.0017 0.0023 0.0021
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0016 0.0003 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0235 0.108
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0192 0.0879
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0137 0.0135
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0356 0.0355
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0778 0.5336
Loa Loa (eye worm) oxidoreductase 0.0016 0.0003 0.0003
Echinococcus granulosus thioredoxin glutathione reductase 0.0095 0.1066 0.1064
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0242 0.3017 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0029 0.0181 0.0296
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0003 0.0001
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0003 0.0001
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0076 0.0298
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0016 0.0003 0.0001
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0003 0.0001
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0027 0.015 0.0488
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0016 0.0003 0.0005
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0235 0.0929
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0242 0.3017 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0309 0.1422
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Schistosoma mansoni lipoxygenase 0.0116 0.1348 0.222
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0107
Echinococcus granulosus cathepsin l1 0.0017 0.0025 0.0023
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0016 0.0003 0.0004
Plasmodium vivax thioredoxin reductase, putative 0.0095 0.1066 0.4916
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0235 0.108
Toxoplasma gondii melibiase subfamily protein 0.0204 0.252 1
Schistosoma mansoni carbonyl reductase 0.0016 0.0003 0.0002
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0569 0.0568
Schistosoma mansoni rab6-interacting 0.0019 0.0055 0.0088
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0271 0.0819
Echinococcus granulosus caspase 8 0.0178 0.2167 0.2166
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0076 0.0509
Trichomonas vaginalis conserved hypothetical protein 0.0178 0.2167 0.6608
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0178 0.2167 0.6608
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0663 0.0661
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0067
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0016 0.0003 0.0005
Toxoplasma gondii thioredoxin reductase 0.0095 0.1066 0.4226
Brugia malayi dehydrogenases, short chain protein 9 0.0016 0.0003 0.0001
Trypanosoma brucei metacaspase 5, putative 0.0178 0.2167 1
Trypanosoma brucei metacaspase MCA2 0.0178 0.2167 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0235 0.0711
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0016 0.0003 0.0005
Trypanosoma cruzi metacaspase, putative 0.0178 0.2167 1
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0029 0.0184 0.1247
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0003 0.0001
Echinococcus multilocularis oxidoreductase 0.0016 0.0003 0.0001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0422 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0076 0.0509
Schistosoma mansoni hypothetical protein 0.0166 0.2004 0.3302
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0027 0.0161 0.0525
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0422 0.0694
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0025 0.0023
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0134 0.0611
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0235 0.108
Plasmodium vivax vivapain-2 0.0017 0.0025 0.0107
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0178 0.2167 0.6608
Onchocerca volvulus 0.0017 0.0025 0.005
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0076 0.0509
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0076 0.0346
Leishmania major short chain dehydrogenase/reductase, putative 0.0016 0.0003 0.0005
Schistosoma mansoni ferritin 0.0017 0.0023 0.0035
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0076 0.0509
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0016 0.0003 0.0004
Schistosoma mansoni caspase-7 (C14 family) 0.047 0.6066 1
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0016 0.0003 0.0005
Brugia malayi dehydrogenases, short chain protein 2 0.0016 0.0003 0.0001
Schistosoma mansoni carbonyl reductase 0.0016 0.0003 0.0002
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0134 0.0525
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0235 0.0711
Onchocerca volvulus 0.0019 0.0055 0.0119
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.1348 0.1346
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0003 0.0005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0271 0.0819
Leishmania major pteridine reductase 1 0.0016 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0065 0.0663 0.109
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0076 0.0509
Plasmodium falciparum metacaspase-like protein 0.0178 0.2167 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Trypanosoma cruzi short chain dehydrogenase, putative 0.0016 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0019 0.0055 0.0088
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0217 0.2694 0.8927
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0025
Schistosoma mansoni alpha-glucosidase 0.0138 0.1641 0.2704
Loa Loa (eye worm) hypothetical protein 0.0343 0.4376 0.4376
Echinococcus granulosus muscleblind protein 0.0765 1 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Trypanosoma cruzi metacaspase, putative 0.0178 0.2167 1
Brugia malayi hypothetical protein 0.0019 0.0055 0.0053
Echinococcus granulosus WW domain containing oxidoreductase 0.0016 0.0003 0.0001
Leishmania major cytochrome p450-like protein 0.0021 0.0076 0.0346
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0422 0.0422
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.006 0.0594 0.2735
Leishmania major oxidoreductase-like protein 0.0016 0.0003 0.0005
Brugia malayi glutathione reductase 0.0095 0.1066 0.1064
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.041 0.041
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0003 0.0005
Brugia malayi hypothetical protein 0.0025 0.0134 0.0132
Trypanosoma brucei metacaspase MCA3 0.0178 0.2167 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0026 0.0137 0.0446
Schistosoma mansoni alpha glucosidase 0.0036 0.0271 0.0444
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0611 0.1005
Trypanosoma cruzi metacaspase 5, putative 0.0178 0.2167 1
Loa Loa (eye worm) hypothetical protein 0.0141 0.167 0.167
Leishmania major cathepsin L-like protease 0.0066 0.067 0.3086
Echinococcus multilocularis RUN 0.0019 0.0055 0.0053
Leishmania major cytochrome p450-like protein 0.003 0.0192 0.0879
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0765 1 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0271 0.027
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0217 0.2694 0.8927
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0569 0.0569
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0235 0.108
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0663 0.0661
Schistosoma mansoni ferritin 0.0017 0.0023 0.0035
Mycobacterium ulcerans Type I modular polyketide synthase 0.0027 0.0161 0.109
Trypanosoma cruzi trypanothione reductase, putative 0.0095 0.1066 0.4916
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0003 0.0005
Echinococcus granulosus oxidoreductase 0.0016 0.0003 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0025 0.0247
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0611 0.061
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0118 0.0117
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0003 0.0004
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0003 0.0001
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0041 0.0342 0.1126
Onchocerca volvulus 0.0017 0.0025 0.005
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.067 0.3086
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0076 0.0245
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0003 0.0001
Toxoplasma gondii type I fatty acid synthase, putative 0.002 0.0055 0.0215
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0482 0.2221
Leishmania major 3-keto-dihydrosphingosine reductase 0.0016 0.0003 0.0005
Leishmania major hypothetical protein, conserved 0.0025 0.0134 0.0611
Echinococcus granulosus apoptotic protease activating factor 1 0.0166 0.2004 0.2003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Loa Loa (eye worm) dehydrogenase 0.0016 0.0003 0.0003
Mycobacterium ulcerans polyketide synthase Pks9 0.0018 0.0037 0.0237
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0235 0.108
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0076 0.0509
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0055 0.0053
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0025 0.0067
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0076 0.0509
Schistosoma mansoni hypothetical protein 0.0065 0.0663 0.109
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0016 0.0003 0.0005
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.194 0.1939
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0235 0.108
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0235 0.0772
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0675 0.2229
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0663 0.0661
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0235 0.5
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0003 0.0005
Echinococcus multilocularis muscleblind protein 0.0765 1 1
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0003 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Echinococcus multilocularis GPCR, family 2 0.0065 0.0663 0.0661
Onchocerca volvulus 0.0017 0.0025 0.005
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0025 0.0107
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0041 0.0342 0.1126
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0076 0.0509
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0234 0.0383
Schistosoma mansoni cytochrome P450 0.0021 0.0076 0.0124
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0004
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0022 0.0089 0.0598
Trypanosoma brucei oxidoreductase-like protein 0.0016 0.0003 0.0005
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0076 0.0245
Loa Loa (eye worm) hypothetical protein 0.0065 0.0663 0.0663
Leishmania major hypothetical protein, conserved 0.0016 0.0003 0.0005
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0003 0.0001
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0778 0.2367
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0023 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0003 0.0001
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0003 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0178 0.2167 1
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0025 0.005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0055 0.0055
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0027 0.0161 0.109
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0016 0.0003 0.0001
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0778 0.2367
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0234 0.0232
Echinococcus multilocularis retinol dehydrogenase 13 0.0016 0.0003 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0134 0.0611
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0076 0.0245
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.047 0.6066 0.6065
Leishmania major hypothetical protein, conserved 0.0016 0.0003 0.0005
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0178 0.2167 0.2166
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Leishmania major hypothetical protein, conserved 0.0016 0.0003 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Schistosoma mansoni loxhd1 0.0019 0.0055 0.0088
Brugia malayi Inositol-1 0.0074 0.0778 0.0776
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0178 0.2167 0.6608
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Brugia malayi Retinol dehydrogenase 12 0.0016 0.0003 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Onchocerca volvulus Cell death protein 3 homolog 0.0343 0.4376 1
Echinococcus multilocularis 0.0021 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0166 0.2004 0.2004
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0023
Loa Loa (eye worm) cysteine protease 0.0017 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0204 0.252 0.4153
Brugia malayi hypothetical protein 0.0016 0.0003 0.0001
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.194 0.1939
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0271 0.3012
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0003 0.0005
Brugia malayi jmjC domain containing protein 0.0058 0.0569 0.0568
Echinococcus granulosus hypothetical protein 0.0016 0.0003 0.0001
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0003 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0076 0.0245
Leishmania major trypanothione reductase 0.0095 0.1066 0.4916
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0178 0.2167 0.6608
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0016 0.0003 0.0001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0235 0.1603
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0076 0.0509
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0023 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Brugia malayi latrophilin 2 splice variant baaae 0.0141 0.167 0.1669
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0023
Schistosoma mansoni rab6-interacting 0.0019 0.0055 0.0088
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0192 0.0192
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0663 0.0661
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0235 0.1603
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0206 0.2538 0.2538
Echinococcus multilocularis apoptotic protease activating factor 1 0.0166 0.2004 0.2003
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0206 0.2538 0.2536
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.067 0.3086
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0204 0.252 0.2519
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0074 0.0778 1
Leishmania major cytochrome p450-like protein 0.0021 0.0076 0.0346
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0076 0.0245
Echinococcus multilocularis caspase 8 0.0178 0.2167 0.2166
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0611 0.4188
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Schistosoma mansoni apoferritin-2 0.0017 0.0023 0.0035
Brugia malayi oxidoreductase 0.0016 0.0003 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0422 0.0421
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0076 0.0245
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0271 0.3012
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.047 0.6066 0.6065
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0611 0.2815
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0235 0.108
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0003 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0003 0.0005
Trypanosoma brucei trypanothione reductase 0.0095 0.1066 0.4916
Echinococcus granulosus ferritin 0.0017 0.0023 0.0021
Leishmania major metacaspase, putative 0.0178 0.2167 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0025 0.0023
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0356 0.1408
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0076 0.0346
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0025 0.0107
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0055 0.0053
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0029 0.0184 0.0601
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0055 0.0053
Leishmania major short chain dehydrogenase, putative 0.0016 0.0003 0.0005
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0229 0.2855 0.2855
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0235 0.0386
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0569 0.0568
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0003 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0235 0.108
Onchocerca volvulus 0.0017 0.0025 0.005
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0235 0.108
Treponema pallidum NADH oxidase 0.0033 0.0235 1
Mycobacterium ulcerans thioesterase TesA 0.0023 0.01 0.067
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0076 0.0245
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0003 0.0001
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0271 0.0819
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0778 0.0776
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Trypanosoma brucei glucosidase, putative 0.0036 0.0271 0.1245
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0029 0.0184 0.0601
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0067
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0271 0.1245
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0016 0.0003 0.0005
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0025 0.005
Toxoplasma gondii carbonyl reductase 1, putative 0.0016 0.0003 0.0004
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.194 0.1939
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0027 0.0161 0.0525
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0204 0.252 0.2519
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0271 0.0819
Plasmodium falciparum metacaspase 1 0.0178 0.2167 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0893 1
Onchocerca volvulus 0.0093 0.1036 0.2362
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0422 0.0421
Schistosoma mansoni inositol monophosphatase 0.0074 0.0778 0.128
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0422 0.0694
Loa Loa (eye worm) hypothetical protein 0.0025 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0082 0.0893 0.0893
Brugia malayi Cytochrome P450 family protein 0.0021 0.0076 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0271 0.0819
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0076 0.0509
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0178 0.2167 0.357
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0569 0.0568
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0076 0.0245
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0025 0.0067
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0019 0.0055 0.0247
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0076 0.0509
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0235 0.3003
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0076 0.0509
Trypanosoma brucei cytochrome P450, putative 0.003 0.0192 0.0879
Leishmania major cathepsin L-like protease 0.0066 0.067 0.3086
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0178 0.2167 0.6608
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0217 0.2694 0.8927
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0124 0.1455 1
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Loa Loa (eye worm) ctsf protein 0.0017 0.0025 0.0025
Schistosoma mansoni ferritin 0.0017 0.0023 0.0035
Schistosoma mansoni hypothetical protein 0.0065 0.0663 0.109
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0192 0.1303
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0611 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0178 0.2167 0.6608
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0192 0.0192
Leishmania major short chain dehydrogenase/reductase, putative 0.0016 0.0003 0.0005
Echinococcus multilocularis geminin 0.0167 0.2026 0.2025
Brugia malayi Melibiase family protein 0.0136 0.1612 0.1611
Brugia malayi hypothetical protein 0.0016 0.0003 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0134 0.0611
Brugia malayi hypothetical protein 0.0166 0.2004 0.2003
Mycobacterium ulcerans polyketide synthase 0.0029 0.0184 0.1247
Echinococcus multilocularis cysteine protease 0.0017 0.0025 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0178 0.2167 0.8597
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0076 0.0245
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0029 0.0184 0.1247
Plasmodium falciparum thioredoxin reductase 0.0095 0.1066 0.4916
Loa Loa (eye worm) fatty acid synthase 0.0027 0.0156 0.0156
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0235 0.108
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0076 0.0509
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0055 0.0245
Trichomonas vaginalis ferritin, putative 0.0017 0.0023 0.0062
Trypanosoma brucei Metacaspase-4 0.0178 0.2167 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0356 0.108
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.0076 0.0245
Leishmania major short chain dehydrogenase-like protein 0.0016 0.0003 0.0005
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0356 0.108
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0016 0.0003 0.0005
Echinococcus granulosus hypothetical protein 0.0016 0.0003 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0234 0.0383
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0235 0.0234
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0107
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0611 0.1005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0234 0.0383
Schistosoma mansoni apoferritin-2 0.0017 0.0023 0.0035
Brugia malayi hypothetical protein 0.0016 0.0014 0.0012
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0235 0.1603
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0003 0.0004
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0095 0.1066 0.3527
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0076 0.0245
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0778 0.3585
Schistosoma mansoni polycystin 1-related 0.0019 0.0055 0.0088
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0055 0.0247
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0022 0.0089 0.0288
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0029 0.0184 0.0601
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0067
Toxoplasma gondii type I fatty acid synthase, putative 0.0029 0.0184 0.0724
Trichomonas vaginalis conserved hypothetical protein 0.0178 0.2167 0.6608
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0134 0.0611
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.1703 0.2806
Loa Loa (eye worm) oxidoreductase 0.0016 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0016 0.0003 0.0005
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0026 0.0137 0.0137
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0422 0.0421
Trichomonas vaginalis set domain proteins, putative 0.0261 0.3277 1
Mycobacterium leprae Polyketide synthase Pks13 0.0041 0.0342 0.1126
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0234 0.0923
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0076 0.0346
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0235 0.7587
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0003 0.0005
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0192 0.0879
Loa Loa (eye worm) CYP4Cod1 0.003 0.0192 0.0192
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0124 0.1455 0.2397
Mycobacterium tuberculosis Probable reductase 0.0217 0.2694 0.8927
Loa Loa (eye worm) thioredoxin reductase 0.0095 0.1066 0.1066
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0235 0.108
Echinococcus granulosus RUN 0.0019 0.0055 0.0053
Brugia malayi Thioredoxin reductase 0.0095 0.1066 0.1064
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0235 0.108
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0235 0.108
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0016 0.0003 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0178 0.2167 0.6608
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0016 0.0003 0.0004
Brugia malayi Cytochrome P450 family protein 0.003 0.0192 0.019
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0025 0.0025
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0027 0.0161 0.016
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0016 0.0003 0.0005
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0356 0.1408
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.194 0.1939
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0076 0.0346
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0076 0.0509
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0271 0.0819
Mycobacterium ulcerans Type I modular polyketide synthase 0.0027 0.0161 0.109
Loa Loa (eye worm) hypothetical protein 0.0019 0.0055 0.0055
Brugia malayi Pre-SET motif family protein 0.0229 0.2855 0.2854
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0271 0.107
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0178 0.2167 0.6608
Toxoplasma gondii Alpha-galactosidase 0.0029 0.0181 0.0712
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0003 0.0005
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0016 0.0003 0.0001
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0178 0.2167 0.8597
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0076 0.0245
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0003 0.0005
Onchocerca volvulus Fatty acid synthase homolog 0.0049 0.0455 0.1034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0067
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Schistosoma mansoni retinal dehydrogenase 0.0016 0.0003 0.0002
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0076 0.0509
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0016 0.0003 0.0005
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0016 0.0003 0.0005
Schistosoma mansoni carbonyl reductase 0.0016 0.0003 0.0002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0235 0.108
Plasmodium falciparum thioredoxin reductase 0.0033 0.0235 0.108
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0016 0.0003 0.0001
Echinococcus multilocularis ferritin 0.0017 0.0023 0.0021
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0076 0.0245
Brugia malayi Cell death protein 3 precursor 0.0343 0.4376 0.4375
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0025 0.0023
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.002 0.0058 0.0183
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Onchocerca volvulus 0.0026 0.0137 0.0307
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0218 0.0216
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0309 0.3444
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0271 0.1245
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0107
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0076 0.0245
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0023
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0025 0.0107
Trypanosoma cruzi metacaspase 5, putative 0.0178 0.2167 1
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0016 0.0003 0.0002
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0178 0.2167 0.6608
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0422 0.0421
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Brugia malayi Doublecortin family protein 0.0019 0.0055 0.0053
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0356 0.1638
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0235 0.0929
Plasmodium vivax steroid dehydrogenase, putative 0.0016 0.0003 0.0005
Echinococcus multilocularis expressed protein 0.0017 0.0023 0.0021
Echinococcus granulosus GPCR family 2 0.0065 0.0663 0.0661
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0016 0.0003 0.0002
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0076 0.0509
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0076 0.0509
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0076 0.0245
Mycobacterium ulcerans polyketide synthase 0.0027 0.0161 0.109
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0107
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0611 0.242
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0016 0.0003 0.0001
Brugia malayi hypothetical protein 0.0019 0.0055 0.0053
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0124 0.1455 0.1454
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0778 0.87
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0663 0.0663
Echinococcus multilocularis conserved hypothetical protein 0.0016 0.0003 0.0001
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0271 0.0271
Plasmodium falciparum glutathione reductase 0.0033 0.0235 0.108
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0235 0.0234
Loa Loa (eye worm) inositol-1 0.0074 0.0778 0.0778
Brugia malayi Pre-SET motif family protein 0.0033 0.0234 0.0232
Echinococcus granulosus caspase 3 0.0292 0.3694 0.3693
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0023
Schistosoma mansoni hypothetical protein 0.0167 0.2026 0.3338
Schistosoma mansoni hypothetical protein 0.0167 0.2026 0.3338
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0235 0.108
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0025 0.0023
Trypanosoma cruzi metacaspase, putative 0.0178 0.2167 1
Trypanosoma brucei metacaspase 0.0178 0.2167 1
Schistosoma mansoni hypothetical protein 0.0021 0.0076 0.0124
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.067 0.3086
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0893 1
Plasmodium vivax glutathione reductase, putative 0.0095 0.1066 0.4916
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0067
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0016 0.0003 0.0001
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0778 0.3585
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Onchocerca volvulus 0.0048 0.0432 0.0982
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.194 0.194
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0611 0.4188
Entamoeba histolytica cysteine protease, putative 0.0017 0.0025 0.0247
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0217 0.2694 0.8927
Brugia malayi Calcitonin receptor-like protein seb-1 0.0206 0.2538 0.2536
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Echinococcus multilocularis cysteine protease 0.0017 0.0025 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0003 0.0005
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0025 0.0025
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0016 0.0003 0.0005
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0076 0.0346
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0025 0.0023
Echinococcus multilocularis caspase 2 0.0343 0.4376 0.4375
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0023 0.0067
Plasmodium vivax metacaspase 1, putative 0.0178 0.2167 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0178 0.2167 0.6608
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0569 0.0936
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0778 0.2367
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0003 0.0002
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0004
Loa Loa (eye worm) dehydrogenase 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.0242 0.3017 1
Echinococcus multilocularis caspase 3 0.0292 0.3694 0.3693
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0778 0.3082
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0076 0.0245
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0025 0.0023
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0076 0.0509
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0136 0.1612 0.2656
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0778 0.3585
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0204 0.252 0.4153
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0018 0.0032 0.0123
Plasmodium falciparum glutathione reductase 0.0095 0.1066 0.4916
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0134 0.0611
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0271 0.027
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0778 0.0776
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0234 0.0383
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0242 0.3017 1
Echinococcus granulosus caspase 2 0.0343 0.4376 0.4375
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0235 0.3003
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0023 0.0139
Mycobacterium ulcerans thioesterase 0.0023 0.01 0.067
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0003 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0235 0.108
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0663 0.0661
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0016 0.0003 0.0005
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0027 0.0161 0.0525
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0052 0.0489 0.0487
Schistosoma mansoni hypothetical protein 0.0065 0.0663 0.109
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0016 0.0003 0.0005
Onchocerca volvulus 0.0017 0.0025 0.005
Loa Loa (eye worm) oxidoreductase 0.0016 0.0003 0.0003
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0835 0.0835
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0076 0.0509
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0001
Mycobacterium leprae putative cytochrome p450 0.0021 0.0076 0.0245
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0204 0.252 0.4153
Toxoplasma gondii cathepsin CPL 0.0017 0.0025 0.0092
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0027 0.0161 0.0525
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0022 0.0089 0.0598
Schistosoma mansoni lipoxygenase 0.0081 0.088 0.145
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0309 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0271 0.0819
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0027 0.0161 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0016 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0178 0.2167 0.6608
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0136 0.1612 0.4915
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0067
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0023 0.01 0.0323
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0055 0.0053
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0003 0.0005
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0025 0.005
Leishmania major quinonoid dihydropteridine reductase 0.0016 0.0003 0.0005
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0675 0.2229
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0118 0.0117
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0016 0.0003 0.0005
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0025 0.0038
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0569 0.0568
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0234 0.0234
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0076 0.0245
Mycobacterium ulcerans Type I modular polyketide synthase 0.0027 0.0161 0.109
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0076 0.0245
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.1703 0.1702
Leishmania major cathepsin L-like protease 0.0066 0.067 0.3086
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0003 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0611 0.2018
Mycobacterium ulcerans polyketide synthase Pks13 0.0041 0.0342 0.2337
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0217 0.2694 0.8927
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0109 0.1248 0.1248
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0016 0.0003 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0569 0.0936
Onchocerca volvulus 0.0019 0.0055 0.0119
Leishmania major dehydrogenase-like protein 0.0016 0.0003 0.0005
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0029 0.0184 0.0601
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0235 0.108
Brugia malayi jmjC domain containing protein 0.0058 0.0569 0.0568
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0025 0.0107
Echinococcus granulosus caspase 0.047 0.6066 0.6065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.067 0.3086
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0018 0.0037 0.0114
Schistosoma mansoni ferritin 0.0017 0.0023 0.0035
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Echinococcus multilocularis muscleblind protein 1 0.0765 1 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0178 0.2167 0.8597
Leishmania major hypothetical protein, conserved 0.0016 0.0003 0.0005
Loa Loa (eye worm) oxidoreductase 0.0016 0.0003 0.0003
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0023
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0124 0.1455 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0055 0.0053
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0235 0.0234
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0124 0.1455 0.6714
Trichomonas vaginalis conserved hypothetical protein 0.0178 0.2167 0.6608
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0003 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0235 0.108
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.067 0.3086
Plasmodium vivax SET domain protein, putative 0.0033 0.0234 0.1073
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0055 0.0053
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0055 0.0055
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0234 0.0232
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0016 0.0003 0.0005
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0018 0.0037 0.0237
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0076 0.0245
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0178 0.2167 0.6608
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0025 0.0023
Loa Loa (eye worm) oxidoreductase 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0022 0.0094 0.0304
Loa Loa (eye worm) acetyltransferase 0.0143 0.1703 0.1703
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0235 0.108
Mycobacterium ulcerans short-chain dehydrogenase 0.0017 0.0025 0.0157
Onchocerca volvulus 0.0261 0.3277 0.7489
Loa Loa (eye worm) oxidoreductase 0.0016 0.0003 0.0003
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0016 0.0003 0.0005
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.1348 0.1346
Brugia malayi Cytochrome P450 family protein 0.003 0.0192 0.019
Schistosoma mansoni ferritin light chain 0.0017 0.0023 0.0035
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0029 0.0184 0.0601
Loa Loa (eye worm) oxidoreductase 0.0016 0.0003 0.0003
Mycobacterium leprae Probable polyketide synthase Pks1 0.0029 0.0184 0.0601
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0136 0.1612 0.2656
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0235 0.108
Plasmodium vivax vivapain-2 0.0017 0.0025 0.0107
Plasmodium falciparum steroid dehydrogenase, putative 0.0016 0.0003 0.0005
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0663 0.0661
Onchocerca volvulus 0.0017 0.0025 0.005
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0271 0.027
Loa Loa (eye worm) hypothetical protein 0.0765 1 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0124 0.1455 0.1454
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0611 0.4188
Onchocerca volvulus 0.0166 0.2004 0.4576
Leishmania major short chain dehydrogenase, putative 0.0016 0.0003 0.0005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.165 0.1648
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0067
Loa Loa (eye worm) oxidoreductase 0.0016 0.0003 0.0003
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0124 0.1455 0.1454
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0124 0.1455 0.4818
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0076 0.0075
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0016 0.0003 0.0005
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0003 0.0001
Schistosoma mansoni alpha-glucosidase 0.0138 0.1641 0.2704
Onchocerca volvulus 0.0017 0.0025 0.005
Loa Loa (eye worm) hypothetical protein 0.0206 0.2538 0.2538
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0023 0.0261
Trypanosoma cruzi short chain dehydrogenase, putative 0.0016 0.0003 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0076 0.0245
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0023 0.0139
Mycobacterium tuberculosis Probable thioesterase TesA 0.0023 0.01 0.0323
Schistosoma mansoni caspase-7 (C14 family) 0.0343 0.4376 0.7213
Echinococcus granulosus steroid dehydrogenase 0.0016 0.0003 0.0001
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0134 0.0611
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0422 0.0694
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0178 0.2167 0.2167
Schistosoma mansoni inositol monophosphatase 0.0074 0.0778 0.128
Schistosoma mansoni ferritin light chain 0.0017 0.0023 0.0035
Brugia malayi Dehydrogenases, short chain protein 2 0.0016 0.0003 0.0001
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0204 0.252 0.2519
Mycobacterium tuberculosis Probable dehydrogenase 0.0217 0.2694 0.8927
Onchocerca volvulus 0.0018 0.004 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0067
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0055 0.0245
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0016 0.0003 0.0001

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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