Detailed information for compound 823341

Basic information

Technical information
  • TDR Targets ID: 823341
  • Name: N-methyl-4-(2-methyl-2,3-dihydro-1,4-benzoxaz in-4-yl)-4-oxobutanamide
  • MW: 262.304 | Formula: C14H18N2O3
  • H donors: 1 H acceptors: 2 LogP: 0.64 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC(=O)CCC(=O)N1CC(C)Oc2c1cccc2
  • InChi: 1S/C14H18N2O3/c1-10-9-16(14(18)8-7-13(17)15-2)11-5-3-4-6-12(11)19-10/h3-6,10H,7-9H2,1-2H3,(H,15,17)
  • InChiKey: INGOEBNLVCLSIV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-methyl-4-(2-methyl-2,3-dihydro-1,4-benzoxazin-4-yl)-4-oxo-butanamide
  • 4-keto-N-methyl-4-(2-methyl-2,3-dihydro-1,4-benzoxazin-4-yl)butyramide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0162 0.0136 0.0136
Mycobacterium ulcerans cell division protein FtsZ 0.061 0.0605 0.4948
Schistosoma mansoni glutamate receptor AMPA 0.0111 0.0083 0.0173
Trypanosoma cruzi histone deacetylase, putative 0.02 0.0176 0.0174
Onchocerca volvulus 0.0154 0.0128 0.038
Echinococcus granulosus lamin 0.006 0.0029 0.0061
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0162 0.0136 0.0283
Echinococcus granulosus histone deacetylase 7 0.0317 0.0298 0.0621
Onchocerca volvulus 0.0039 0.0007 0.0018
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Plasmodium vivax hypothetical protein, conserved 0.0144 0.0117 0.0444
Loa Loa (eye worm) hypothetical protein 0.0058 0.0027 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0244 0.0222 0.0461
Loa Loa (eye worm) solute carrier family 6 member 4 0.0848 0.0854 0.0854
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Trypanosoma cruzi extracellular receptor, putative 0.0039 0.0007 0.0005
Echinococcus granulosus tubulin subunit TubB 0.1836 0.1888 0.393
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0162 0.0136 0.0136
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0154 0.0128 0.0266
Trichomonas vaginalis tubulin beta chain, putative 0.1836 0.1888 0.7249
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Trypanosoma cruzi zeta tubulin, putative 0.061 0.0605 0.0603
Brugia malayi Bromodomain containing protein 0.0088 0.0059 0.0058
Leishmania major histone deacetylase, putative 0.0317 0.0298 0.0296
Loa Loa (eye worm) neuropeptide F receptor 0.0154 0.0128 0.0127
Loa Loa (eye worm) tubulin alpha 2 0.1226 0.1249 0.1249
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0162 0.0136 0.0136
Schistosoma mansoni nuclear receptor 0.0071 0.0041 0.0086
Brugia malayi 6-phosphofructokinase 0.0125 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0135 0.0108 0.0226
Brugia malayi Muscleblind-like protein 0.0483 0.0472 0.0472
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0331 0.0313 0.0652
Schistosoma mansoni hypothetical protein 0.0641 0.0638 0.1328
Loa Loa (eye worm) CBP-B 0.0091 0.0062 0.0062
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0154 0.0128 0.0127
Schistosoma mansoni hypothetical protein 0.0135 0.0108 0.0226
Loa Loa (eye worm) 6-phosphofructokinase 0.0125 0.0097 0.0097
Loa Loa (eye worm) serotonin transporter b 0.0848 0.0854 0.0854
Entamoeba histolytica histone deacetylase, putative 0.0577 0.057 0.2183
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0428 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.008 0.005 0.005
Echinococcus multilocularis hypothetical protein 0.1836 0.1888 0.393
Echinococcus granulosus histone deacetylase 6 0.0317 0.0298 0.0621
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0041 0.0086
Schistosoma mansoni sodium/chloride dependent transporter 0.0848 0.0854 0.1779
Loa Loa (eye worm) hypothetical protein 0.0084 0.0055 0.0055
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0299 0.028 0.2438
Echinococcus multilocularis beta LACTamase domain containing family member 0.008 0.005 0.0105
Trichomonas vaginalis tubulin epsilon chain, putative 0.061 0.0605 0.2318
Brugia malayi PAS domain containing protein 0.0056 0.0025 0.0025
Echinococcus granulosus Tubulin alpha 1 chain 0.1836 0.1888 0.393
Echinococcus multilocularis protoporphyrinogen oxidase 0.0084 0.0055 0.0115
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0162 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Plasmodium falciparum tubulin beta chain 0.252 0.2603 1
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) tubulin beta-4 chain 0.252 0.2603 0.2603
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.005 0.0185
Trichomonas vaginalis tubulin epsilon chain, putative 0.1836 0.1888 0.7249
Brugia malayi hypothetical protein 0.0131 0.0104 0.0103
Trypanosoma brucei alpha tubulin 0.1836 0.1888 0.1886
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Trypanosoma cruzi alpha tubulin, putative 0.1836 0.1888 0.1886
Brugia malayi GnHR receptor homolog 0.0154 0.0128 0.0127
Onchocerca volvulus TPPP family protein homolog 0.042 0.0406 0.1217
Schistosoma mansoni coup transcription factor 0.0162 0.0136 0.0283
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0174 0.0148 0.0563
Loa Loa (eye worm) dihydrofolate reductase 0.005 0.0019 0.0019
Brugia malayi nuclear receptor RXR 0.0091 0.0062 0.0061
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Schistosoma mansoni opsin-like receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.0102 0.0102
Schistosoma mansoni neuropeptide F-like receptor 0.0154 0.0128 0.0266
Plasmodium vivax tubulin epsilon chain, putative 0.1405 0.1437 0.5516
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0119 0.0092 0.0191
Loa Loa (eye worm) transcription factor SMAD2 0.1902 0.1957 0.1957
Onchocerca volvulus 0.0039 0.0007 0.0018
Echinococcus granulosus Tubulin beta 2C chain 0.252 0.2603 0.5419
Echinococcus granulosus tubulin alpha chain 0.1836 0.1888 0.393
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0036 0.0005 0.001
Onchocerca volvulus 0.0795 0.0799 0.2396
Echinococcus granulosus dro:myosuppressin receptor 0.0154 0.0128 0.0266
Echinococcus multilocularis dro:myosuppressin receptor 0.0154 0.0128 0.0266
Schistosoma mansoni sodium/chloride dependent transporter 0.0144 0.0117 0.0245
Loa Loa (eye worm) intermediate filament protein 0.006 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0162 0.0136 0.0136
Brugia malayi hypothetical protein 0.0641 0.0638 0.0638
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0154 0.0128 0.0266
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.0043 0.0158
Loa Loa (eye worm) beta-lactamase 0.008 0.005 0.005
Echinococcus multilocularis Tubulin beta 2C chain 0.252 0.2603 0.5419
Echinococcus granulosus g protein coupled receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Plasmodium falciparum ataxin-2 like protein, putative 0.0289 0.0269 0.1027
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.0021 0.0045
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0043 0.0158
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0033 0.0068
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0299 0.028 0.0278
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0061 0.003 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0043 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0283 0.0263 0.0547
Loa Loa (eye worm) MH2 domain-containing protein 0.0058 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0641 0.0638 0.2444
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0033 0.0068
Brugia malayi Tubulin alpha chain 0.061 0.0605 0.0605
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0144 0.0117 0.0117
Echinococcus multilocularis thyroid hormone receptor alpha 0.0306 0.0287 0.0598
Loa Loa (eye worm) hypothetical protein 0.2381 0.2458 0.2457
Echinococcus multilocularis orexin receptor type 2 0.0154 0.0128 0.0266
Plasmodium vivax histone deacetylase, putative 0.02 0.0176 0.067
Echinococcus granulosus histone deacetylase 6 0.0342 0.0325 0.0676
Onchocerca volvulus 0.0049 0.0018 0.005
Schistosoma mansoni hypothetical protein 0.0089 0.006 0.0124
Plasmodium falciparum alpha tubulin 1 0.1836 0.1888 0.7249
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0043 0.0041
Echinococcus granulosus G protein coupled receptor 139 0.0154 0.0128 0.0266
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0089 0.006 0.0124
Echinococcus granulosus biogenic amine 5HT receptor 0.4623 0.4804 1
Brugia malayi Tubulin beta-1 chain 0.252 0.2603 0.2603
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0194 0.017 1
Mycobacterium leprae cell division protein FtsZ 0.061 0.0605 1
Echinococcus granulosus tubulin alpha 3 chain 0.1836 0.1888 0.393
Loa Loa (eye worm) hypothetical protein 0.008 0.005 0.005
Schistosoma mansoni lamin 0.006 0.0029 0.0061
Echinococcus granulosus tubulin beta 1 chain 0.252 0.2603 0.5419
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Mycobacterium tuberculosis Probable oxidoreductase 0.0138 0.0111 0.094
Echinococcus granulosus lysine specific histone demethylase 1A 0.0084 0.0055 0.0115
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0061
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0146 0.0555
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1041 0.1056 0.4051
Trypanosoma brucei beta tubulin 0.252 0.2603 0.2602
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.061 0.0605 0.2318
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0162 0.0136 0.0283
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0135 0.0108 0.0226
Brugia malayi ORL1-like opioid receptor 0.0154 0.0128 0.0127
Brugia malayi Tubulin beta chain 0.0795 0.0799 0.0798
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0154 0.0128 0.0266
Loa Loa (eye worm) steroid hormone receptor 0.0162 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0162 0.0136 0.0136
Echinococcus multilocularis g protein coupled receptor 0.0154 0.0128 0.0266
Echinococcus multilocularis neuropeptide FF receptor 2 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.1041 0.1056 0.1056
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0071 0.0041 0.0041
Brugia malayi jmjC domain containing protein 0.0063 0.0033 0.0033
Mycobacterium ulcerans monoamine oxidase 0.0084 0.0055 0.0434
Schistosoma mansoni hypothetical protein 0.0154 0.0128 0.0266
Trypanosoma cruzi zeta tubulin, putative 0.061 0.0605 0.0603
Leishmania major zeta tubulin, putative 0.061 0.0605 0.0603
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0039 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0061
Brugia malayi hypothetical protein 0.0076 0.0046 0.0046
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0036 0.0005 0.001
Trichomonas vaginalis tubulin alpha chain, putative 0.0795 0.0799 0.3062
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0124 0.0096 0.0096
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0299 0.028 0.0582
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.0577 0.057 0.057
Leishmania major ATP-dependent phosphofructokinase 0.0125 0.0097 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0162 0.0136 0.0136
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Echinococcus granulosus metabotropic glutamate receptor 5 0.0039 0.0007 0.0015
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0154 0.0128 0.0266
Plasmodium falciparum transporter, putative 0.0144 0.0117 0.0444
Brugia malayi hypothetical protein 0.0289 0.0269 0.0269
Echinococcus multilocularis peroxisome assembly protein 26 0.1836 0.1888 0.393
Schistosoma mansoni amine oxidase 0.0084 0.0055 0.0115
Schistosoma mansoni thyroid hormone receptor 0.0306 0.0287 0.0598
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0146 0.0555
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0145 0.0118 0.0246
Schistosoma mansoni hypothetical protein 0.0135 0.0108 0.0226
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0244 0.0222 0.0221
Trichomonas vaginalis tubulin gamma chain, putative 0.1405 0.1437 0.5516
Leishmania major beta tubulin 0.252 0.2603 0.2602
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.01 0.0072 0.0269
Brugia malayi Bromodomain containing protein 0.0049 0.0018 0.0017
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.015 0.0124 0.0257
Brugia malayi hypothetical protein 0.0091 0.0062 0.0061
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0097 0.0366
Loa Loa (eye worm) G-protein coupled receptor 0.0154 0.0128 0.0127
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0033 0.0068
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.0162 0.0136 0.0136
Brugia malayi Nuclear hormone receptor-like 1 0.0091 0.0062 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Loa Loa (eye worm) BEN-1 protein 0.252 0.2603 0.2603
Echinococcus multilocularis sodium and chloride dependent glycine 0.0144 0.0117 0.0245
Brugia malayi MH2 domain containing protein 0.0058 0.0027 0.0027
Brugia malayi histone deacetylase 3 (HD3) 0.0577 0.057 0.057
Mycobacterium ulcerans 6-phosphofructokinase 0.0125 0.0097 0.078
Echinococcus granulosus neuropeptide receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) isocitrate dehydrogenase 0.0299 0.028 0.0279
Echinococcus granulosus vesicular acetylcholine transporter 0.3213 0.3329 0.6929
Echinococcus granulosus tubulin alpha 1C chain 0.1836 0.1888 0.393
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0088 0.0059 0.09
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0162 0.0136 0.0136
Brugia malayi steroid hormone receptor 0.0162 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) pax transcription factor protein 2 0.1507 0.1543 0.1543
Loa Loa (eye worm) hypothetical protein 0.0144 0.0117 0.0117
Plasmodium falciparum glutathione reductase 0.0054 0.0024 0.0083
Trichomonas vaginalis tubulin epsilon chain, putative 0.252 0.2603 1
Echinococcus multilocularis nmda type glutamate receptor 0.0283 0.0263 0.0547
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1114 0.1132 1
Brugia malayi intermediate filament protein 0.006 0.0029 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0021 0.0045
Plasmodium vivax tubulin alpha chain, putative 0.1836 0.1888 0.7249
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0162 0.0136 0.0136
Plasmodium falciparum amino acid transporter, putative 0.0144 0.0117 0.0444
Brugia malayi tailless protein 0.0071 0.0041 0.0041
Plasmodium vivax tubulin beta chain, putative 0.252 0.2603 1
Plasmodium vivax SET domain protein, putative 0.0035 0.0003 0.0005
Schistosoma mansoni Smad4 0.0058 0.0027 0.0057
Echinococcus granulosus neuropeptide receptor A26 0.0682 0.068 0.1416
Brugia malayi Dopamine receptor protein 2 0.0154 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Toxoplasma gondii histone lysine-specific demethylase 0.0084 0.0055 0.0204
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0041 0.0086
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0039 0.0007 0.0015
Plasmodium vivax glutathione reductase, putative 0.0054 0.0024 0.0083
Trichomonas vaginalis tubulin beta chain, putative 0.1836 0.1888 0.7249
Onchocerca volvulus 0.0162 0.0136 0.0405
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0041 0.012
Schistosoma mansoni TGF-beta signal transducer Smad2 0.013 0.0102 0.0213
Trypanosoma cruzi histone deacetylase, putative 0.0317 0.0298 0.0296
Echinococcus granulosus 6 phosphofructokinase 0.0125 0.0097 0.0203
Echinococcus multilocularis tubulin alpha 3 chain 0.1836 0.1888 0.393
Chlamydia trachomatis endonuclease IV 0.0088 0.0059 0.3387
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Echinococcus multilocularis cpg binding protein 0.0037 0.0005 0.0011
Brugia malayi larval opioid receptor 0.0154 0.0128 0.0127
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.061 0.0605 0.2318
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Schistosoma mansoni smad 0.0058 0.0027 0.0057
Giardia lamblia Beta tubulin 0.252 0.2603 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0262 0.024 0.024
Echinococcus granulosus biogenic amine 5HT receptor 0.2381 0.2458 0.5116
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.005 0.0048
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0146 0.0555
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0041 0.0086
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0144 0.0117 0.0245
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0154 0.0128 0.0266
Loa Loa (eye worm) latrophilin receptor protein 2 0.0135 0.0108 0.0108
Trichomonas vaginalis histone deacetylase, putative 0.0577 0.057 0.2183
Loa Loa (eye worm) hypothetical protein 0.0483 0.0472 0.0472
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0641 0.0638 0.1328
Plasmodium vivax hypothetical protein, conserved 0.008 0.005 0.0185
Trypanosoma brucei tubulin delta chain 0.061 0.0605 0.0603
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1199 0.1221 1
Echinococcus multilocularis dihydrofolate reductase 0.005 0.0019 0.004
Loa Loa (eye worm) BEN-1 protein 0.252 0.2603 0.2603
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0299 0.028 0.0278
Entamoeba histolytica tartrate dehydrogenase, putative 0.0036 0.0005 0.0011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0162 0.0136 0.0283
Onchocerca volvulus 0.006 0.0029 0.0085
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Echinococcus granulosus glutamate receptor 2 0.015 0.0124 0.0257
Brugia malayi acetyltransferase, GNAT family protein 0.0331 0.0313 0.0313
Echinococcus granulosus hypothetical protein 0.0154 0.0128 0.0266
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0154 0.0128 0.0266
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0144 0.0117 0.0245
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0071 0.0041 0.0086
Toxoplasma gondii beta tubulin 0.252 0.2603 1
Trichomonas vaginalis tubulin gamma chain, putative 0.061 0.0605 0.2318
Loa Loa (eye worm) G-protein coupled receptor 0.0154 0.0128 0.0127
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0061 0.003 0.0227
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0041 0.0086
Onchocerca volvulus 0.0154 0.0128 0.038
Trypanosoma brucei beta tubulin 0.1405 0.1437 0.1435
Entamoeba histolytica tubulin family protein 0.252 0.2603 1
Trypanosoma cruzi C-8 sterol isomerase, putative 0.959 1 1
Toxoplasma gondii isocitrate dehydrogenase 0.0299 0.028 0.1068
Loa Loa (eye worm) hypothetical protein 0.0848 0.0854 0.0854
Echinococcus multilocularis rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Echinococcus multilocularis neuropeptide receptor 0.0154 0.0128 0.0266
Echinococcus multilocularis neuropeptide Y receptor 0.0154 0.0128 0.0266
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0096 0.0068 0.0141
Leishmania major beta tubulin 0.252 0.2603 0.2602
Leishmania major hypothetical protein, conserved 0.0289 0.0269 0.0267
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Echinococcus granulosus alpha tubulin 0.1836 0.1888 0.393
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.015 0.0124 0.0257
Echinococcus granulosus jun protein 0.0096 0.0068 0.0141
Trypanosoma brucei PAB1-binding protein , putative 0.0289 0.0269 0.0267
Echinococcus multilocularis glutamate receptor 2 0.015 0.0124 0.0257
Echinococcus multilocularis transfer RNA-Lys 0.0041 0.001 0.0021
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0125 0.0097 0.1118
Brugia malayi Dopamine receptor protein 1 0.0154 0.0128 0.0127
Loa Loa (eye worm) Smad1 0.013 0.0102 0.0102
Mycobacterium tuberculosis Probable conserved lipoprotein 0.008 0.005 0.0404
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.005 0.0185
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.006 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0035 0.0004 0.0003
Leishmania major histone deacetylase, putative 0.0317 0.0298 0.0296
Onchocerca volvulus 0.0154 0.0128 0.038
Brugia malayi Isocitrate dehydrogenase 0.0299 0.028 0.0279
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0002 0.0002
Brugia malayi dihydrofolate reductase family protein 0.005 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Plasmodium falciparum histone deacetylase 1 0.0577 0.057 0.2183
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.013 0.0102 0.0213
Loa Loa (eye worm) tubulin beta chain 0.252 0.2603 0.2603
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0162 0.0136 0.0283
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Trichomonas vaginalis tubulin beta chain, putative 0.1836 0.1888 0.7249
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Brugia malayi 6-phosphofructokinase 0.0125 0.0097 0.0097
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0039 0.0007 0.0007
Echinococcus granulosus sodium and chloride dependent glycine 0.0144 0.0117 0.0245
Schistosoma mansoni tubulin subunit beta 0.252 0.2603 0.5419
Schistosoma mansoni ap endonuclease 0.0061 0.003 0.0063
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0162 0.0136 0.0283
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0144 0.0117 0.0245
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0002 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0091 0.0062 0.0061
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0001 0.0001
Toxoplasma gondii alpha tubulin TUBA1 0.1836 0.1888 0.7249
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0162 0.0136 0.0136
Onchocerca volvulus 0.008 0.005 0.0147
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0144 0.0117 0.0245
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1836 0.1888 0.7249
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0071 0.0041 0.0086
Mycobacterium ulcerans endonuclease IV 0.0088 0.0059 0.0465
Giardia lamblia Alpha-tubulin 0.1836 0.1888 0.7249
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.4901 0.5095 0.5095
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Echinococcus granulosus GPCR family 2 0.0135 0.0108 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0084 0.0055 0.0055
Brugia malayi PHD-finger family protein 0.0037 0.0006 0.0005
Echinococcus multilocularis sex peptide receptor 0.0154 0.0128 0.0266
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0144 0.0117 0.0117
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.01 0.0072 0.0269
Brugia malayi Metabotropic glutamate receptor precursor. 0.0039 0.0007 0.0007
Brugia malayi Pax transcription factor protein 2 0.1507 0.1543 0.1543
Brugia malayi TAZ zinc finger family protein 0.0127 0.0099 0.0099
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0154 0.0128 0.0127
Mycobacterium tuberculosis Probable dehydrogenase 0.0124 0.0096 0.0812
Loa Loa (eye worm) tubulin alpha 2 0.1226 0.1249 0.1249
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0174 0.0148 0.0146
Schistosoma mansoni histone deacetylase 0.0577 0.057 0.1186
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0418 0.0404 0.0404
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0091 0.0062 0.0061
Trypanosoma brucei zeta tubulin, putative 0.061 0.0605 0.0603
Echinococcus multilocularis histone deacetylase 7 0.0317 0.0298 0.0621
Leishmania major gamma-tubulin 0.1405 0.1437 0.1435
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.003 0.0109
Echinococcus multilocularis musashi 0.006 0.0029 0.0061
Schistosoma mansoni tubulin subunit alpha 0.1836 0.1888 0.393
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0174 0.0148 0.0563
Echinococcus multilocularis rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0097 0.0366
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0124 0.0096 0.0812
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0041 0.0086
Trypanosoma cruzi histone deacetylase 1, putative 0.0577 0.057 0.0568
Brugia malayi MH2 domain containing protein 0.013 0.0102 0.0102
Echinococcus granulosus g protein coupled receptor 0.0154 0.0128 0.0266
Leishmania major epsilon tubulin, putative 0.1405 0.1437 0.1435
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0144 0.0117 0.0117
Echinococcus granulosus chromobox protein 1 0.008 0.005 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0154 0.0128 0.0266
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.008 0.005 0.0404
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0577 0.057 0.2183
Leishmania major trypanothione reductase 0.0054 0.0024 0.0021
Echinococcus granulosus Tubulin beta 2C chain 0.252 0.2603 0.5419
Mycobacterium tuberculosis Probable hydrolase 0.008 0.005 0.0404
Loa Loa (eye worm) MH2 domain-containing protein 0.1902 0.1957 0.1957
Onchocerca volvulus 0.0154 0.0128 0.038
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0084 0.0055 0.0115
Trichomonas vaginalis tubulin beta-1 chain, putative 0.061 0.0605 0.2318
Schistosoma mansoni bromodomain containing protein 0.0076 0.0046 0.0096
Trypanosoma cruzi histone deacetylase, putative 0.0317 0.0298 0.0296
Mycobacterium leprae Probable lipase LipE 0.008 0.005 0.0758
Echinococcus multilocularis Tubulin beta 2C chain 0.252 0.2603 0.5419
Toxoplasma gondii histone deacetylase HDAC5 0.02 0.0176 0.067
Loa Loa (eye worm) nuclear factor I 0.0072 0.0042 0.0041
Onchocerca volvulus 0.0154 0.0128 0.038
Schistosoma mansoni RAR-like nuclear receptor 0.0162 0.0136 0.0283
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0054 0.0024 0.0167
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Brugia malayi Melatonin receptor type 1A 0.0154 0.0128 0.0127
Trichomonas vaginalis tubulin, putative 0.061 0.0605 0.2318
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Echinococcus granulosus serotonin receptor 0.0154 0.0128 0.0266
Echinococcus multilocularis rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Echinococcus granulosus smad 0.013 0.0102 0.0213
Brugia malayi thymidylate synthase 0.0123 0.0096 0.0095
Echinococcus granulosus cpg binding protein 0.0037 0.0005 0.0011
Echinococcus multilocularis tubulin alpha chain 0.1836 0.1888 0.393
Echinococcus granulosus Tubulin alpha 1 chain 0.1836 0.1888 0.393
Toxoplasma gondii hypothetical protein 0.0144 0.0117 0.0444
Mycobacterium ulcerans putative regulatory protein 0.0041 0.001 0.0064
Brugia malayi tubulin alpha-2 chain 0.1836 0.1888 0.1887
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0146 0.0555
Loa Loa (eye worm) hypothetical protein 0.0072 0.0042 0.0041
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0036 0.0005 0.0011
Echinococcus granulosus allatostatin A receptor 0.0154 0.0128 0.0266
Schistosoma mansoni tubulin subunit gamma 0.1405 0.1437 0.2991
Loa Loa (eye worm) hypothetical protein 0.02 0.0176 0.0176
Giardia lamblia Alpha-tubulin 0.1836 0.1888 0.7249
Schistosoma mansoni tyrosine kinase 0.0039 0.0007 0.0015
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0071 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.3565 0.3697 0.7696
Brugia malayi latrophilin 2 splice variant baaae 0.0293 0.0273 0.0272
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0144 0.0117 0.0245
Leishmania major beta tubulin 0.252 0.2603 0.2602
Schistosoma mansoni tubulin subunit beta 0.252 0.2603 0.5419
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0144 0.0117 0.0245
Mycobacterium ulcerans oxidoreductase 0.0084 0.0055 0.0434
Brugia malayi hypothetical protein 0.0144 0.0117 0.0117
Trypanosoma brucei hypothetical protein, conserved 0.008 0.005 0.0048
Echinococcus multilocularis tubulin subunit beta 0.252 0.2603 0.5419
Echinococcus multilocularis mothers against decapentaplegic 2 0.0058 0.0027 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0162 0.0136 0.0136
Trypanosoma cruzi UDP-galactopyranose mutase 0.0084 0.0055 0.0053
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0299 0.028 0.0278
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.015 0.0124 0.0257
Echinococcus granulosus Smad4 0.013 0.0102 0.0213
Echinococcus multilocularis 6 phosphofructokinase 0.0125 0.0097 0.0203
Loa Loa (eye worm) histone deacetylase 3 0.0577 0.057 0.057
Leishmania major beta tubulin 0.252 0.2603 0.2602
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0154 0.0128 0.0266
Brugia malayi Tachykinin-like peptides receptor 99D 0.0154 0.0128 0.0127
Echinococcus granulosus tubulin alpha 3 chain 0.1836 0.1888 0.393
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0154 0.0128 0.0266
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0299 0.028 0.0582
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Echinococcus granulosus tubulin alpha chain 0.1836 0.1888 0.393
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0084 0.0055 0.0115
Brugia malayi AKH receptor 0.0154 0.0128 0.0127
Echinococcus multilocularis geminin 0.3565 0.3697 0.7696
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0144 0.0117 0.6882
Echinococcus granulosus tubulin alpha 0.1405 0.1437 0.2991
Chlamydia trachomatis glutamine binding protein 0.0194 0.017 1
Trypanosoma brucei alpha tubulin 0.1836 0.1888 0.1886
Brugia malayi Receptor family ligand binding region containing protein 0.0039 0.0007 0.0007
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.013 0.0102 0.0213
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Schistosoma mansoni hypothetical protein 0.0293 0.0273 0.0568
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0124 0.0096 0.0812
Schistosoma mansoni hypothetical protein 0.0154 0.0128 0.0266
Schistosoma mansoni neuropeptide receptor 0.0154 0.0128 0.0266
Brugia malayi hypothetical protein 0.0059 0.0028 0.0028
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Schistosoma mansoni amine GPCR 0.0154 0.0128 0.0266
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0084 0.0055 0.0204
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0033 0.0068
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0162 0.0136 0.0283
Loa Loa (eye worm) alpha-tubulin 0.1836 0.1888 0.1887
Schistosoma mansoni 6-phosphofructokinase 0.0125 0.0097 0.0203
Schistosoma mansoni hypothetical protein 0.0113 0.0085 0.0177
Echinococcus granulosus neuropeptide receptor 0.0154 0.0128 0.0266
Echinococcus granulosus g-protein coupled receptor 0.0154 0.0128 0.0266
Schistosoma mansoni alpha tubulin 0.1836 0.1888 0.393
Brugia malayi putative neuropeptide receptor 0.0154 0.0128 0.0127
Echinococcus granulosus beta tubulin 0.252 0.2603 0.5419
Loa Loa (eye worm) 6-phosphofructokinase 0.0125 0.0097 0.0097
Leishmania major beta tubulin 0.252 0.2603 0.2602
Onchocerca volvulus 0.011 0.0082 0.0242
Echinococcus multilocularis G-protein coupled receptor, putative 0.0154 0.0128 0.0266
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0331 0.0313 0.0652
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0194 0.017 0.1463
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.024 0.0916
Schistosoma mansoni jun-related protein 0.0078 0.0049 0.0101
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0154 0.0128 0.0127
Brugia malayi nuclear receptor NHR-67 0.0071 0.0041 0.0041
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0071 0.0041 0.0086
Schistosoma mansoni hypothetical protein 0.013 0.0102 0.0213
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0154 0.0128 0.0266
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0084 0.0055 0.0838
Onchocerca volvulus 0.0154 0.0128 0.038
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0089 0.006 0.0124
Schistosoma mansoni hypothetical protein 0.3565 0.3697 0.7696
Echinococcus multilocularis histone deacetylase 6 0.0317 0.0298 0.0621
Leishmania major beta tubulin 0.252 0.2603 0.2602
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0144 0.0117 0.0444
Schistosoma mansoni steroid hormone receptor ad4bp 0.0162 0.0136 0.0283
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0096 0.0068 0.0141
Brugia malayi MH1 domain containing protein 0.0072 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0061
Brugia malayi hypothetical protein 0.0187 0.0163 0.0162
Mycobacterium tuberculosis Possible penicillin-binding protein 0.051 0.05 0.4395
Plasmodium falciparum tubulin epsilon chain, putative 0.1405 0.1437 0.5516
Brugia malayi nuclear hormone receptor family member odr-7 0.0071 0.0041 0.0041
Echinococcus multilocularis histone deacetylase 1 0.0577 0.057 0.1186
Echinococcus granulosus geminin 0.3565 0.3697 0.7696
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0174 0.0148 0.0146
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0036 0.0005 0.001
Brugia malayi Probable isocitrate dehydrogenase 0.0036 0.0005 0.0004
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0039 0.0007 0.0015
Trichomonas vaginalis histone deacetylase, putative 0.0577 0.057 0.2183
Leishmania major beta tubulin 0.252 0.2603 0.2602
Loa Loa (eye worm) hypothetical protein 0.0131 0.0104 0.0103
Schistosoma mansoni tubulin subunit beta 0.252 0.2603 0.5419
Echinococcus granulosus g protein coupled receptor 0.0154 0.0128 0.0266
Brugia malayi jmjC domain containing protein 0.0067 0.0037 0.0037
Schistosoma mansoni lamin 0.006 0.0029 0.0061
Onchocerca volvulus 0.0076 0.0046 0.0134
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0071 0.0041 0.0086
Echinococcus multilocularis glutamate receptor 2 0.0111 0.0083 0.0173
Trichomonas vaginalis tubulin beta chain, putative 0.1836 0.1888 0.7249
Schistosoma mansoni adenoreceptor 0.0154 0.0128 0.0266
Echinococcus granulosus glutamate NMDA receptor subunit 0.0111 0.0083 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0162 0.0136 0.0136
Schistosoma mansoni biogenic amine receptor 0.0154 0.0128 0.0266
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0043 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0154 0.0128 0.0266
Echinococcus granulosus lysine specific demethylase 5A 0.0067 0.0037 0.0077
Giardia lamblia Epsilon tubulin 0.061 0.0605 0.2318
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0154 0.0128 0.0266
Echinococcus multilocularis histone deacetylase 6 0.0317 0.0298 0.0621
Loa Loa (eye worm) hypothetical protein 0.0142 0.0115 0.0115
Echinococcus multilocularis tubulin gamma 1 chain 0.1405 0.1437 0.2991
Toxoplasma gondii alpha-tubulin I, putative 0.1836 0.1888 0.7249
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0043 0.0158
Echinococcus granulosus sex peptide receptor 0.0154 0.0128 0.0266
Brugia malayi phosphofructokinase 0.0125 0.0097 0.0097
Echinococcus multilocularis Tubulin alpha 1 chain 0.1836 0.1888 0.393
Brugia malayi G protein-coupled receptor 0.0154 0.0128 0.0127
Schistosoma mansoni inositol monophosphatase 0.0073 0.0043 0.009
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0043 0.0041
Onchocerca volvulus 0.0144 0.0117 0.0349
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Schistosoma mansoni 6-phosphofructokinase 0.0125 0.0097 0.0203
Loa Loa (eye worm) hypothetical protein 0.0055 0.0024 0.0024
Trypanosoma cruzi epsilon tubulin, putative 0.1405 0.1437 0.1435
Echinococcus multilocularis somatostatin receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0091 0.0062 0.0128
Onchocerca volvulus 0.0867 0.0873 0.2621
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0144 0.0117 0.0245
Brugia malayi putative neuropeptide receptor NPR1 0.0154 0.0128 0.0127
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0144 0.0117 0.0245
Echinococcus multilocularis FTZ F1 alpha 0.0162 0.0136 0.0283
Echinococcus multilocularis histone deacetylase 6 0.0342 0.0325 0.0676
Leishmania major isocitrate dehydrogenase, putative 0.0036 0.0005 0.0003
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.015 0.0124 0.0257
Echinococcus multilocularis tubulin alpha chain 0.1836 0.1888 0.393
Plasmodium vivax tubulin gamma chain, putative 0.1405 0.1437 0.5516
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0065 0.0035 0.027
Trichomonas vaginalis tubulin beta chain, putative 0.0795 0.0799 0.3062
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0123 0.0096 0.0807
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0162 0.0136 0.0136
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.1722 0.1769 0.1768
Plasmodium falciparum tubulin delta chain, putative 0.061 0.0605 0.2318
Brugia malayi Smad1 0.013 0.0102 0.0102
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0135 0.0108 0.0226
Loa Loa (eye worm) hypothetical protein 0.0084 0.0055 0.0055
Loa Loa (eye worm) alpha-tubulin 0.1836 0.1888 0.1887
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Trypanosoma brucei histone deacetylase 4 0.0317 0.0298 0.0296
Schistosoma mansoni tyrosine kinase 0.0039 0.0007 0.0015
Schistosoma mansoni tubulin subunit alpha 0.1836 0.1888 0.393
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0061
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0299 0.028 0.0582
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0162 0.0136 0.0136
Trypanosoma brucei histone deacetylase 1 0.0577 0.057 0.0568
Brugia malayi Receptor family ligand binding region containing protein 0.0039 0.0007 0.0007
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0162 0.0136 0.0283
Onchocerca volvulus 0.0123 0.0096 0.0284
Giardia lamblia Beta tubulin 0.252 0.2603 1
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Brugia malayi nuclear hormone receptor 0.0162 0.0136 0.0136
Brugia malayi G-protein coupled receptor 0.0154 0.0128 0.0127
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0125 0.0097 0.0095
Echinococcus multilocularis Tubulin beta 2C chain 0.252 0.2603 0.5419
Schistosoma mansoni ATP-binding cassette transporter 0.0111 0.0083 0.0173
Loa Loa (eye worm) hypothetical protein 0.0036 0.0005 0.0004
Brugia malayi Dihydrofolate reductase 0.005 0.0019 0.0019
Brugia malayi hypothetical protein 0.0084 0.0055 0.0055
Echinococcus granulosus beta tubulin 0.252 0.2603 0.5419
Brugia malayi hypothetical protein 0.0091 0.0062 0.0061
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0154 0.0128 0.0266
Echinococcus granulosus single minded 2 0.0041 0.001 0.0021
Leishmania major beta tubulin 0.252 0.2603 0.2602
Schistosoma mansoni biogenic amine (5HT) receptor 0.2381 0.2458 0.5116
Toxoplasma gondii histone deacetylase HDAC1 0.0317 0.0298 0.1138
Onchocerca volvulus 0.008 0.005 0.0147
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0017 0.0058
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0125 0.0097 0.0095
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.0043 0.0158
Schistosoma mansoni neuropeptide F-like receptor 0.0154 0.0128 0.0266
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0154 0.0128 0.0266
Loa Loa (eye worm) beta-tubulin 0.252 0.2603 0.2603
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.003 0.0109
Brugia malayi Calcitonin receptor-like protein seb-1 0.0428 0.0414 0.0414
Brugia malayi G protein-coupled receptor F59B2.13 0.0154 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.0051 0.002 0.002
Echinococcus granulosus glutamate receptor 2 0.0061 0.0031 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0156 0.0592
Echinococcus multilocularis g protein coupled receptor 0.0154 0.0128 0.0266
Schistosoma mansoni glutamate receptor kainate 0.0111 0.0083 0.0173
Schistosoma mansoni hypothetical protein 0.0154 0.0128 0.0266
Toxoplasma gondii exonuclease III APE 0.0061 0.003 0.0109
Echinococcus multilocularis thymidylate synthase 0.0123 0.0096 0.02
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0299 0.028 0.0582
Loa Loa (eye worm) hypothetical protein 0.0187 0.0163 0.0162
Brugia malayi nuclear receptor NHR-88 0.0071 0.0041 0.0041
Echinococcus granulosus serotonin transporter 0.0848 0.0854 0.1779
Onchocerca volvulus 0.0154 0.0128 0.038
Schistosoma mansoni tubulin subunit alpha 0.1836 0.1888 0.393
Echinococcus granulosus mothers against decapentaplegic 5 0.013 0.0102 0.0213
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.005 0.0185
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0144 0.0117 0.0245
Trichomonas vaginalis histone deacetylase, putative 0.0577 0.057 0.2183
Brugia malayi tubulin alpha chain - mouse 0.1836 0.1888 0.1887
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0135 0.0108 0.0226
Echinococcus multilocularis muscleblind protein 1 0.0483 0.0472 0.0983
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0162 0.0136 0.0283
Loa Loa (eye worm) hypothetical protein 0.959 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.024 0.0916
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.005 0.0019 0.0243
Echinococcus granulosus beta LACTamase domain containing family member 0.008 0.005 0.0105
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.0043 0.0158
Loa Loa (eye worm) tubulin alpha chain 0.1836 0.1888 0.1887
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0154 0.0128 0.0266
Brugia malayi bHLH-PAS transcription factor 0.0041 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0154 0.0128 0.0266
Echinococcus multilocularis synaptic vesicular amine transporter 0.1722 0.1769 0.3682
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0154 0.0128 0.0266
Schistosoma mansoni neuropeptide receptor 0.0154 0.0128 0.0266
Onchocerca volvulus 0.0154 0.0128 0.038
Schistosoma mansoni aryl hydrocarbon receptor 0.0056 0.0026 0.0054
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1199 0.1221 1
Echinococcus multilocularis tubulin alpha chain 0.1836 0.1888 0.393
Echinococcus granulosus orexin receptor type 2 0.0154 0.0128 0.0266
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0123 0.0096 0.1517
Echinococcus multilocularis isocitrate dehydrogenase 0.0299 0.028 0.0582
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0162 0.0136 0.0136
Plasmodium falciparum histone deacetylase, putative 0.0317 0.0298 0.1138
Loa Loa (eye worm) hypothetical protein 0.1836 0.1888 0.1887
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0154 0.0128 0.0266
Echinococcus granulosus tubulin subunit beta 0.252 0.2603 0.5419
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0146 0.0555
Onchocerca volvulus 0.0042 0.0011 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0043 0.0041
Mycobacterium leprae conserved hypothetical protein 0.008 0.005 0.0758
Trypanosoma brucei histone deacetylase 2 0.02 0.0176 0.0174
Echinococcus multilocularis muscleblind protein 0.0483 0.0472 0.0983
Echinococcus multilocularis tubulin alpha 1C chain 0.1836 0.1888 0.393
Echinococcus granulosus neuropeptide Y receptor 0.0154 0.0128 0.0266
Echinococcus multilocularis tubulin, beta 4A class IVa 0.252 0.2603 0.5419
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0048 0.0017 0.0036
Onchocerca volvulus 0.1507 0.1543 0.4635
Echinococcus multilocularis vesicular acetylcholine transporter 0.3213 0.3329 0.6929
Schistosoma mansoni alpha tubulin 0.1836 0.1888 0.393
Schistosoma mansoni ap endonuclease 0.0061 0.003 0.0063
Schistosoma mansoni nuclear receptor nhr-48 0.0071 0.0041 0.0086
Schistosoma mansoni hypothetical protein 0.0049 0.0018 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Onchocerca volvulus 0.008 0.005 0.0147
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0154 0.0128 0.0127
Schistosoma mansoni dihydrofolate reductase 0.005 0.0019 0.004
Loa Loa (eye worm) MH1 domain-containing protein 0.0058 0.0027 0.0027
Onchocerca volvulus 0.0091 0.0062 0.0181
Echinococcus multilocularis TGF beta signal transducer SmadC 0.013 0.0102 0.0213
Schistosoma mansoni smad1 5 8 and 0.013 0.0102 0.0213
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0036 0.0005 0.001
Brugia malayi beta-lactamase family protein 0.008 0.005 0.005
Entamoeba histolytica hypothetical protein 0.0641 0.0638 0.2444
Brugia malayi nuclear hormone receptor family member nhr-6 0.0071 0.0041 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0162 0.0136 0.0136
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0003 0.0007
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0037 0.0037
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.005 0.0019 0.0141
Toxoplasma gondii histone deacetylase HDAC3 0.0577 0.057 0.2183
Schistosoma mansoni tubulin subunit beta 0.252 0.2603 0.5419
Loa Loa (eye worm) glutamate receptor 0.0039 0.0007 0.0007
Brugia malayi neuropeptide F receptor 0.0154 0.0128 0.0127
Echinococcus granulosus intermediate filament protein 0.006 0.0029 0.0061
Plasmodium vivax hypothetical protein, conserved 0.0084 0.0055 0.0204
Schistosoma mansoni glutamate receptor AMPA 0.0111 0.0083 0.0173
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.005 0.0105
Echinococcus granulosus Tubulin beta 2C chain 0.252 0.2603 0.5419
Brugia malayi Abnormal catecholamine distribution protein 1 0.1722 0.1769 0.1768
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0154 0.0128 0.0266
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0005 0.001
Echinococcus granulosus alpha 1A adrenergic receptor 0.0154 0.0128 0.0266
Brugia malayi nuclear receptor NHR-88 0.0162 0.0136 0.0136
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0125 0.0097 0.1542
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0091 0.0062 0.0128
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Onchocerca volvulus Huntingtin homolog 0.0131 0.0104 0.0308
Loa Loa (eye worm) thymidylate synthase 0.0123 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Entamoeba histolytica hypothetical protein 0.0039 0.0007 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0244 0.0222 0.0461
Loa Loa (eye worm) glutamate receptor 1 0.0111 0.0083 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0162 0.0136 0.0136
Echinococcus multilocularis tyrosine kinase 0.0039 0.0007 0.0015
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.003 0.0109
Toxoplasma gondii beta-tubulin, putative 0.252 0.2603 1
Schistosoma mansoni glutamate receptor kainate 0.0111 0.0083 0.0173
Trypanosoma cruzi tubulin delta chain 0.061 0.0605 0.0603
Echinococcus granulosus histone deacetylase 6 0.0317 0.0298 0.0621
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0097 0.0366
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0028 0.01
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0154 0.0128 0.038
Mycobacterium ulcerans dehydrogenase 0.0084 0.0055 0.0434
Brugia malayi hypothetical protein 0.0322 0.0304 0.0303
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0124 0.0096 0.1525
Echinococcus multilocularis tubulin alpha 1C chain 0.1836 0.1888 0.393
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0084 0.0055 0.0115
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0154 0.0128 0.0266
Brugia malayi Steroid receptor seven-up type 2 0.0162 0.0136 0.0136
Schistosoma mansoni histone deacetylase 4 5 0.0317 0.0298 0.0621
Brugia malayi ecdysone receptor 0.0071 0.0041 0.0041
Echinococcus granulosus tyrosine kinase 0.0039 0.0007 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.005 0.0105
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0007 0.0007
Giardia lamblia Histone acetyltransferase GCN5 0.0088 0.0059 0.0219
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0154 0.0128 0.0266
Trypanosoma cruzi UDP-galactopyranose mutase 0.0084 0.0055 0.0053
Echinococcus multilocularis Tubulin beta 2C chain 0.252 0.2603 0.5419
Brugia malayi MH1 domain containing protein 0.013 0.0102 0.0102
Brugia malayi beta-lactamase family protein 0.008 0.005 0.005
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0194 0.017 0.1968
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0084 0.0055 0.0204
Echinococcus multilocularis g protein coupled receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) tubulin alpha chain 0.1836 0.1888 0.1887
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Leishmania major beta tubulin 0.252 0.2603 0.2602
Echinococcus granulosus histone deacetylase 0.0317 0.0298 0.0621
Brugia malayi Tubulin alpha-2 chain 0.1836 0.1888 0.1887
Mycobacterium tuberculosis Probable esterase LipL 0.008 0.005 0.0404
Brugia malayi MH1 domain containing protein 0.013 0.0102 0.0102
Brugia malayi MH2 domain containing protein 0.013 0.0102 0.0102
Echinococcus granulosus histone acetyltransferase KAT2B 0.0317 0.0299 0.0622
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0299 0.028 0.1068
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.005 0.0185
Trypanosoma cruzi Emopamil binding protein, putative 0.0867 0.0873 0.0871
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0144 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0084 0.0055 0.0055
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0174 0.0148 0.0563
Loa Loa (eye worm) hypothetical protein 0.008 0.005 0.005
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.015 0.0124 0.0257
Toxoplasma gondii thioredoxin reductase 0.0054 0.0024 0.0083
Echinococcus granulosus thyroid hormone receptor alpha 0.0071 0.0041 0.0086
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Echinococcus multilocularis tubulin alpha chain 0.1836 0.1888 0.393
Schistosoma mansoni neuropeptide receptor 0.0154 0.0128 0.0266
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.0217 0.0452
Echinococcus multilocularis rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0041 0.0086
Leishmania major hypothetical protein, conserved 0.008 0.005 0.0048
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0037 0.0077
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0123 0.0096 0.02
Onchocerca volvulus 0.0154 0.0128 0.038
Loa Loa (eye worm) hypothetical protein 0.0144 0.0117 0.0117
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0061 0.003 0.0231
Echinococcus granulosus 7TM GPCR rhodopsin 0.0154 0.0128 0.0266
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0162 0.0136 0.0283
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0089 0.006 0.0124
Onchocerca volvulus Neuropeptide F receptor homolog 0.0154 0.0128 0.038
Schistosoma mansoni tubulin subunit beta 0.252 0.2603 0.5419
Loa Loa (eye worm) hypothetical protein 0.0055 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Echinococcus granulosus peroxisome assembly protein 26 0.1836 0.1888 0.393
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.008 0.005 0.005
Leishmania major histone deacetylase, putative 0.0577 0.057 0.0568
Trypanosoma brucei tubulin gamma chain 0.1405 0.1437 0.1435
Onchocerca volvulus Bile acid receptor homolog 0.0162 0.0136 0.0405
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.015 0.0124 0.0257
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Onchocerca volvulus 0.0071 0.0041 0.012
Loa Loa (eye worm) hypothetical protein 0.0135 0.0108 0.0108
Trichomonas vaginalis tubulin, putative 0.252 0.2603 1
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.024 0.0916
Loa Loa (eye worm) hypothetical protein 0.0116 0.0089 0.0088
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0867 0.0873 0.0871
Schistosoma mansoni protein kinase 0.0039 0.0007 0.0015
Brugia malayi isocitrate dehydrogenase 0.0299 0.028 0.0279
Loa Loa (eye worm) hypothetical protein 0.0052 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0162 0.0136 0.0136
Toxoplasma gondii histone deacetylase HDAC4 0.02 0.0176 0.067
Schistosoma mansoni amine GPCR 0.0154 0.0128 0.0266
Plasmodium vivax histone deacetylase, putative 0.0317 0.0298 0.1138
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0039 0.0007 0.0007
Echinococcus multilocularis allatostatin A receptor 0.0154 0.0128 0.0266
Schistosoma mansoni histone deacetylase 1 2 3 0.02 0.0176 0.0367
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0244 0.0222 0.0221
Echinococcus multilocularis serotonin receptor 0.2381 0.2458 0.5116
Loa Loa (eye worm) phosphofructokinase 0.0125 0.0097 0.0097
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0162 0.0136 0.0136
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0089 0.006 0.0124
Echinococcus multilocularis g-protein coupled receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0084 0.0055 0.0055
Schistosoma mansoni unc-13 (munc13) 0.0036 0.0005 0.001
Brugia malayi Histone deacetylase 1 0.0577 0.057 0.057
Brugia malayi Cytochrome P450 family protein 0.0088 0.0059 0.0059
Loa Loa (eye worm) p25-alpha family protein 0.042 0.0406 0.0406
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Echinococcus multilocularis chromobox protein 1 0.008 0.005 0.0105
Echinococcus multilocularis neuropeptide receptor 0.0154 0.0128 0.0266
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.0043 0.0337
Schistosoma mansoni vesicular acetylcholine transporter 0.3213 0.3329 0.6929
Brugia malayi hypothetical protein 0.0071 0.0041 0.0041
Brugia malayi Thioredoxin reductase 0.0054 0.0024 0.0023
Onchocerca volvulus 0.0154 0.0128 0.038
Schistosoma mansoni vesicular amine transporter 0.1722 0.1769 0.3682
Brugia malayi hypothetical protein 0.0187 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0162 0.0136 0.0136
Echinococcus multilocularis jun protein 0.0096 0.0068 0.0141
Echinococcus granulosus tubulin alpha chain 0.1836 0.1888 0.393
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.024 0.0916
Trypanosoma cruzi beta tubulin, putative 0.252 0.2603 0.2602
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0146 0.0555
Brugia malayi photoreceptor-specific nuclear receptor 0.0162 0.0136 0.0136
Brugia malayi alpha-tubulin 0.1836 0.1888 0.1887
Echinococcus granulosus neuropeptides capa receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0162 0.0136 0.0136
Echinococcus granulosus rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Mycobacterium tuberculosis Hypothetical protein 0.0059 0.0028 0.0207
Onchocerca volvulus 0.0144 0.0117 0.0349
Trichomonas vaginalis tubulin gamma chain, putative 0.1405 0.1437 0.5516
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.008 0.005 0.0394
Giardia lamblia Delta tubulin 0.061 0.0605 0.2318
Leishmania major C-8 sterol isomerase-like protein 0.959 1 1
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.0043 0.009
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.003 0.0109
Schistosoma mansoni neuropeptide f receptor 76f 0.0154 0.0128 0.0266
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0037 0.0077
Brugia malayi Serotonin receptor 0.1111 0.1129 0.1129
Toxoplasma gondii beta-1 tubulin, putative 0.252 0.2603 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0154 0.0128 0.0266
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.015 0.0124 0.0257
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0795 0.0799 0.3062
Brugia malayi SWIRM domain containing protein 0.0084 0.0055 0.0055
Leishmania major beta tubulin 0.252 0.2603 0.2602
Loa Loa (eye worm) hypothetical protein 0.0162 0.0136 0.0136
Loa Loa (eye worm) tubulin beta chain 0.061 0.0605 0.0605
Brugia malayi hypothetical protein 0.024 0.0217 0.0217
Brugia malayi RE15519p 0.0154 0.0128 0.0127
Brugia malayi Cell division protein ftsZ 0.061 0.0605 0.0605
Echinococcus multilocularis ecdysone induced protein 78C 0.0162 0.0136 0.0283
Schistosoma mansoni smad1 5 8 and 0.013 0.0102 0.0213
Trichomonas vaginalis histone deacetylase, putative 0.0577 0.057 0.2183
Onchocerca volvulus 0.0154 0.0128 0.038
Echinococcus multilocularis sodium and chloride dependent glycine 0.0144 0.0117 0.0245
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0123 0.0096 0.0095
Echinococcus multilocularis thioredoxin glutathione reductase 0.0054 0.0024 0.0049
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0061 0.003 0.0109
Leishmania major beta tubulin 0.252 0.2603 0.2602
Echinococcus granulosus FTZ F1 alpha 0.0162 0.0136 0.0283
Plasmodium falciparum histone acetyltransferase GCN5 0.0088 0.0059 0.0219
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0088 0.0059 0.0058
Echinococcus granulosus tm gpcr rhodopsin 0.0154 0.0128 0.0266
Echinococcus granulosus tubulin delta chain 0.061 0.0605 0.126
Brugia malayi exodeoxyribonuclease III family protein 0.0061 0.003 0.003
Trichomonas vaginalis tubulin alpha chain, putative 0.1405 0.1437 0.5516
Schistosoma mansoni amine GPCR 0.0154 0.0128 0.0266
Brugia malayi Cytochrome P450 family protein 0.0034 0.0002 0.0002
Echinococcus granulosus tubulin beta 4A class IVa 0.252 0.2603 0.5419
Schistosoma mansoni histamine h1 receptor 0.0154 0.0128 0.0266
Mycobacterium tuberculosis Cell division protein FtsZ 0.061 0.0605 0.5324
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0154 0.0128 0.0266
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0135 0.0108 0.0226
Leishmania major delta tubulin, putative 0.061 0.0605 0.0603
Brugia malayi mothers against decapentaplegic homolog 3 0.0058 0.0027 0.0027
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0036 0.0005 0.0004
Schistosoma mansoni tubulin subunit beta 0.252 0.2603 0.5419
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0144 0.0117 0.0245
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0162 0.0136 0.0283
Mycobacterium ulcerans esterase/lipase LipP 0.008 0.005 0.0394
Trypanosoma brucei epsilon tubulin 0.1405 0.1437 0.1435
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0001 0.0003
Brugia malayi sulfakinin receptor protein 0.0154 0.0128 0.0127
Schistosoma mansoni isocitrate dehydrogenase 0.0036 0.0005 0.001
Treponema pallidum exodeoxyribonuclease (exoA) 0.0061 0.003 0.0333
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Echinococcus granulosus fmrfamide receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Trichomonas vaginalis tubulin, putative 0.0795 0.0799 0.3062
Echinococcus multilocularis Tubulin beta 2C chain 0.252 0.2603 0.5419
Echinococcus multilocularis tubulin subunit TubB 0.1836 0.1888 0.393
Brugia malayi conserved hypotetical protein 0.0071 0.0041 0.0041
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Toxoplasma gondii histone lysine methyltransferase SET1 0.0076 0.0046 0.0171
Loa Loa (eye worm) norepinephrine transporter 0.0848 0.0854 0.0854
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Schistosoma mansoni histone deacetylase hda2 0.0342 0.0325 0.0676
Schistosoma mansoni hypothetical protein 0.0154 0.0128 0.0266
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Schistosoma mansoni hypothetical protein 0.0078 0.0049 0.0101
Echinococcus multilocularis nmda type glutamate receptor 0.0039 0.0007 0.0015
Echinococcus multilocularis neuropeptides capa receptor 0.0154 0.0128 0.0266
Schistosoma mansoni amine GPCR 0.0154 0.0128 0.0266
Schistosoma mansoni sodium-dependent amino acid transporter 0.0144 0.0117 0.0245
Schistosoma mansoni amine oxidase 0.0084 0.0055 0.0115
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0065 0.0035 0.0507
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0244 0.0222 0.0461
Giardia lamblia Gamma tubulin 0.1405 0.1437 0.5516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Brugia malayi neuropeptide F receptor 0.0154 0.0128 0.0127
Trypanosoma cruzi histone deacetylase 1, putative 0.0577 0.057 0.0568
Echinococcus granulosus metabotropic glutamate receptor 2 0.0039 0.0007 0.0015
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0162 0.0136 0.0283
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Echinococcus multilocularis rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.1226 0.1249 0.1249
Brugia malayi ecdysteroid receptor 0.0162 0.0136 0.0136
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0089 0.006 0.0124
Brugia malayi Cytochrome P450 family protein 0.0034 0.0002 0.0002
Echinococcus granulosus neuropeptide FF receptor 2 0.0154 0.0128 0.0266
Schistosoma mansoni neuropeptide receptor 0.0154 0.0128 0.0266
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.015 0.0124 0.0257
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0124 0.0096 0.0812
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0144 0.0117 0.0117
Echinococcus multilocularis tubulin delta chain 0.061 0.0605 0.126
Loa Loa (eye worm) hypothetical protein 0.0483 0.0472 0.0472
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0154 0.0128 0.0266
Chlamydia trachomatis protoporphyrinogen oxidase 0.0084 0.0055 0.3162
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2625 0.2713 0.5648
Mycobacterium tuberculosis Conserved protein 0.008 0.005 0.0404
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0154 0.0128 0.0127
Entamoeba histolytica acetyltransferase, GNAT family 0.0088 0.0059 0.0219
Toxoplasma gondii hypothetical protein 0.0144 0.0117 0.0444
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0097 0.0366
Trichomonas vaginalis tubulin beta chain, putative 0.1836 0.1888 0.7249
Trichomonas vaginalis conserved hypothetical protein 0.061 0.0605 0.2318
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0061
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0086 0.0057 0.0212
Trichomonas vaginalis bromodomain-containing protein, putative 0.01 0.0072 0.0269
Onchocerca volvulus Histone deacetylase 10 homolog 0.02 0.0176 0.0526
Onchocerca volvulus Protein ultraspiracle homolog 0.0162 0.0136 0.0405
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0127 0.0099 0.0207
Loa Loa (eye worm) DR-78 0.0071 0.0041 0.0041
Brugia malayi Nuclear hormone receptor-like 1 0.0162 0.0136 0.0136
Mycobacterium tuberculosis Probable lipase LipD 0.008 0.005 0.0404
Brugia malayi hypothetical protein 0.0071 0.0041 0.0041
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0144 0.0117 0.0245
Schistosoma mansoni myosin xvIII 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0144 0.0117 0.0117
Onchocerca volvulus 0.0154 0.0128 0.038
Onchocerca volvulus 0.0154 0.0128 0.038
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0091 0.0062 0.0128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0088 0.0059 0.0479
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0162 0.0136 0.0283
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0041 0.0041
Echinococcus granulosus Tubulin alpha 1 chain 0.1836 0.1888 0.393
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0061 0.003 0.0109
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0144 0.0117 0.0245
Plasmodium falciparum ataxin-2 like protein, putative 0.0289 0.0269 0.1027
Brugia malayi Guanylyl cyclase protein 23 0.0039 0.0007 0.0007
Schistosoma mansoni lipoxygenase 0.0119 0.0092 0.0191
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) tubulin beta-1 chain 0.252 0.2603 0.2603
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0005 0.001
Brugia malayi orphan nuclear receptor NR2E1 0.0071 0.0041 0.0041
Echinococcus granulosus tubulin alpha chain 0.1836 0.1888 0.393
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0144 0.0117 0.0245
Plasmodium vivax hypothetical protein, conserved 0.0084 0.0055 0.0204
Echinococcus granulosus mothers against decapentaplegic 2 0.0058 0.0027 0.0057
Plasmodium vivax delta tubulin, putative 0.061 0.0605 0.2318
Schistosoma mansoni tubulin subunit delta 0.061 0.0605 0.126
Trypanosoma brucei Emopamil binding protein, putative 0.0867 0.0873 0.0871
Mycobacterium ulcerans lipase LipD 0.008 0.005 0.0394
Treponema pallidum cell division protein FtsZ 0.061 0.0605 0.7075
Onchocerca volvulus 0.006 0.0029 0.0085
Schistosoma mansoni chromobox protein 0.008 0.005 0.0105
Loa Loa (eye worm) hypothetical protein 0.008 0.005 0.005
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0867 0.0873 0.0871
Brugia malayi histone deacetylase 11 0.02 0.0176 0.0176
Onchocerca volvulus 0.0035 0.0004 0.0007
Schistosoma mansoni intermediate filament proteins 0.006 0.0029 0.0061
Brugia malayi histone deacetylase 1 (HD1) 0.0577 0.057 0.057
Schistosoma mansoni metabotropic glutamate receptor 0.0039 0.0007 0.0015
Loa Loa (eye worm) alpha-tubulin isotype 2 0.1226 0.1249 0.1249
Echinococcus multilocularis neuropeptides capa receptor 0.0154 0.0128 0.0266
Schistosoma mansoni sodium/chloride dependent transporter 0.0144 0.0117 0.0245
Schistosoma mansoni hypothetical protein 0.0135 0.0108 0.0226
Echinococcus multilocularis lamin 0.006 0.0029 0.0061
Schistosoma mansoni opsin-like receptor 0.0154 0.0128 0.0266
Echinococcus granulosus neuropeptide s receptor 0.0682 0.068 0.1416
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0036 0.0005 0.001
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.0043 0.0641
Schistosoma mansoni alpha-1 adrenergic receptor 0.0154 0.0128 0.0266
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0088 0.0059 0.0218
Echinococcus granulosus nmda type glutamate receptor 0.0039 0.0007 0.0015
Echinococcus multilocularis Tubulin alpha 1 chain 0.1836 0.1888 0.393
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0154 0.0128 0.0127
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0125 0.0097 0.0821
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0577 0.057 0.2183
Leishmania major beta tubulin 0.252 0.2603 0.2602
Trypanosoma brucei beta tubulin 0.252 0.2603 0.2602
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Trypanosoma brucei histone deacetylase 3 0.0317 0.0298 0.0296
Leishmania major beta tubulin 0.252 0.2603 0.2602
Schistosoma mansoni glutamate receptor kainate 0.0111 0.0083 0.0173
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0162 0.0136 0.0283
Onchocerca volvulus 0.0154 0.0128 0.038
Leishmania major beta tubulin 0.252 0.2603 0.2602
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0059 0.0059
Echinococcus multilocularis tubulin epsilon chain 0.1405 0.1437 0.2991
Echinococcus granulosus CREB binding protein 0.0127 0.0099 0.0207
Brugia malayi Tubulin beta chain 0.061 0.0605 0.0605
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0014 0.0037
Echinococcus multilocularis tubulin alpha chain 0.1836 0.1888 0.393
Plasmodium vivax amine transporter, putative 0.0144 0.0117 0.0444
Schistosoma mansoni cpg binding protein 0.0033 0.0001 0.0003
Schistosoma mansoni histone deacetylase 4 5 0.0317 0.0298 0.0621
Brugia malayi glutathione reductase 0.0054 0.0024 0.0023
Echinococcus multilocularis nuclear receptor nhr 48 0.0071 0.0041 0.0086
Onchocerca volvulus 0.0273 0.0252 0.0754
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0641 0.0638 0.1328
Plasmodium vivax histone acetyltransferase GCN5, putative 0.01 0.0072 0.0269
Echinococcus granulosus ecdysone induced protein 78C 0.0162 0.0136 0.0283
Plasmodium vivax histone deacetylase 1, putative 0.0577 0.057 0.2183
Loa Loa (eye worm) histone deacetylase 11 0.02 0.0176 0.0176
Schistosoma mansoni retinoic acid receptor RXR 0.0275 0.0255 0.053
Brugia malayi Latrophilin receptor protein 2 0.0135 0.0108 0.0108
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0154 0.0128 0.0266
Echinococcus granulosus TGF beta signal transducer SmadC 0.013 0.0102 0.0213
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.1405 0.1437 0.5516
Brugia malayi Tubulin alpha-2 chain 0.1836 0.1888 0.1887
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0039 0.0007 0.0007
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0144 0.0117 0.0245
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.008 0.005 0.005
Schistosoma mansoni alpha tubulin 0.1836 0.1888 0.393
Echinococcus multilocularis histone deacetylase 0.0317 0.0298 0.0621
Loa Loa (eye worm) hypothetical protein 0.024 0.0217 0.0217
Toxoplasma gondii isocitrate dehydrogenase 0.0299 0.028 0.1068
Schistosoma mansoni histone deacetylase 0.0577 0.057 0.1186
Brugia malayi Heterochromatin protein 1 0.008 0.005 0.005
Schistosoma mansoni cpg binding protein 0.0037 0.0005 0.0011
Plasmodium falciparum tubulin gamma chain 0.1405 0.1437 0.5516
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0154 0.0128 0.0127
Trichomonas vaginalis histone deacetylase, putative 0.0577 0.057 0.2183
Mycobacterium tuberculosis Possible oxidoreductase 0.0084 0.0055 0.0446
Trichomonas vaginalis tubulin beta chain, putative 0.1836 0.1888 0.7249
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0041 0.012
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0084 0.0055 0.0204
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0428 0.0414 0.0414
Schistosoma mansoni Smad4 0.0058 0.0027 0.0057
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0184 0.016 0.0333
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0275 0.0255 0.053
Echinococcus multilocularis beta tubulin 0.252 0.2603 0.5419
Trypanosoma brucei histone deacetylase, putative 0.0317 0.0298 0.0296
Echinococcus granulosus histone deacetylase 3 0.0577 0.057 0.1186
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0299 0.028 0.0278
Echinococcus granulosus 7tm_1 domain containing protein 0.0154 0.0128 0.0266
Loa Loa (eye worm) melatonin receptor type 1A 0.0154 0.0128 0.0127
Schistosoma mansoni amine GPCR 0.0154 0.0128 0.0266
Brugia malayi Glutamate receptor 2 precursor 0.0111 0.0083 0.0083
Schistosoma mansoni cpg binding protein 0.0037 0.0005 0.0011
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0162 0.0136 0.0283
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0097 0.0366
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Leishmania major beta tubulin 0.252 0.2603 0.2602
Entamoeba histolytica tubulin family protein 0.252 0.2603 1
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0194 0.017 0.1375
Schistosoma mansoni tubulin subunit epsilon 0.1405 0.1437 0.2991
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.3213 0.3329 0.3328
Echinococcus granulosus synaptic vesicular amine transporter 0.1722 0.1769 0.3682
Schistosoma mansoni survival motor neuron protein 0.0049 0.0018 0.0037
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0094 0.0065 0.0065
Echinococcus granulosus neuropeptides capa receptor 0.0154 0.0128 0.0266
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0138 0.0111 0.094
Schistosoma mansoni biogenic amine receptor 0.0154 0.0128 0.0266
Onchocerca volvulus 0.0144 0.0117 0.0349
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0061 0.003 0.0427
Leishmania major extracellular receptor, putative 0.0039 0.0007 0.0005
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0003 0.0005
Mycobacterium tuberculosis Conserved protein 0.008 0.005 0.0404
Brugia malayi metabotropic glutamate receptor type 2 0.0039 0.0007 0.0007
Trypanosoma brucei beta tubulin 0.252 0.2603 0.2602
Trypanosoma cruzi tubulin gamma chain 0.1405 0.1437 0.1435
Schistosoma mansoni tubulin subunit beta 0.061 0.0605 0.126
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0299 0.028 0.0582
Brugia malayi Tubulin alpha chain 0.1836 0.1888 0.1887
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) glutamate receptor 2 0.0111 0.0083 0.0083
Plasmodium vivax histone deacetylase 2, putative 0.0317 0.0298 0.1138
Trichomonas vaginalis chromobox protein, putative 0.008 0.005 0.0186
Mycobacterium tuberculosis Conserved protein 0.008 0.005 0.0404
Echinococcus multilocularis tumor protein p63 0.0751 0.0752 0.1566
Echinococcus granulosus tm gpcr rhodopsin 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0036 0.0005 0.0004
Entamoeba histolytica hypothetical protein 0.0641 0.0638 0.2444
Trypanosoma brucei alpha tubulin 0.1836 0.1888 0.1886
Brugia malayi nuclear hormone receptor 0.0071 0.0041 0.0041
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0018 0.0018
Trypanosoma cruzi PAB1-binding protein , putative 0.0289 0.0269 0.0267
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0124 0.0096 0.0812
Loa Loa (eye worm) hypothetical protein 0.2381 0.2458 0.2457
Plasmodium falciparum histone deacetylase 2 0.0317 0.0298 0.1138
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0299 0.028 0.1068
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0144 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0144 0.0117 0.0117
Echinococcus multilocularis Smad4 0.013 0.0102 0.0213
Loa Loa (eye worm) acetyltransferase 0.0331 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.0162 0.0136 0.0136
Schistosoma mansoni CREB-binding protein 2 0.0127 0.0099 0.0207
Loa Loa (eye worm) nuclear hormone receptor 0.0071 0.0041 0.0041
Echinococcus granulosus tubulin epsilon chain 0.1405 0.1437 0.2991
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0162 0.0136 0.0283
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0061 0.003 0.0028
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0244 0.0222 0.0461
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0174 0.0148 0.0146
Loa Loa (eye worm) glutathione reductase 0.0054 0.0024 0.0023
Echinococcus multilocularis chromobox protein 1 0.008 0.005 0.0105
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0039 0.0007 0.0018
Schistosoma mansoni hypothetical protein 0.0145 0.0118 0.0246
Echinococcus multilocularis rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0061 0.003 0.0063
Trichomonas vaginalis set domain proteins, putative 0.0273 0.0252 0.0961
Loa Loa (eye worm) neuropeptide F receptor 0.0154 0.0128 0.0127
Onchocerca volvulus 0.0091 0.0062 0.0181
Echinococcus multilocularis histone deacetylase 8 0.02 0.0176 0.0367
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0061 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0088 0.0059 0.0058
Brugia malayi bZIP transcription factor family protein 0.0096 0.0068 0.0067
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0138 0.0111 0.1766
Loa Loa (eye worm) hypoxia-induced factor 1 0.0173 0.0148 0.0147
Echinococcus multilocularis GPCR, family 2 0.0135 0.0108 0.0226
Plasmodium falciparum thioredoxin reductase 0.0054 0.0024 0.0083
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0013
Schistosoma mansoni biogenic amine receptor 0.0154 0.0128 0.0266
Leishmania major beta tubulin 0.252 0.2603 0.2602
Echinococcus multilocularis tubulin alpha 0.1405 0.1437 0.2991
Onchocerca volvulus 0.0084 0.0055 0.0162
Brugia malayi chromobox protein homolog 3 0.0045 0.0014 0.0013
Echinococcus multilocularis serotonin transporter 0.0848 0.0854 0.1779
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0848 0.0854 0.1779
Echinococcus multilocularis receptor type guanylyl cyclase 0.0039 0.0007 0.0015
Brugia malayi MH1 domain containing protein 0.0072 0.0042 0.0041
Echinococcus granulosus histone acetyltransferase KAT2B 0.01 0.0072 0.015
Onchocerca volvulus 0.0154 0.0128 0.038
Echinococcus multilocularis biogenic amine (5HT) receptor 0.4623 0.4804 1
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.005 0.0185
Echinococcus granulosus neuropeptide Y receptor 0.0154 0.0128 0.0266
Schistosoma mansoni single-minded 0.0056 0.0025 0.0052
Mycobacterium tuberculosis Conserved hypothetical protein 0.0084 0.0055 0.0446
Schistosoma mansoni nuclear receptor 0.0071 0.0041 0.0086
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.0043 0.009
Schistosoma mansoni chromobox protein 0.008 0.005 0.0105
Trypanosoma brucei epsilon tubulin 0.1405 0.1437 0.1435
Schistosoma mansoni cellular tumor antigen P53 0.011 0.0082 0.017
Trichomonas vaginalis tubulin alpha chain, putative 0.252 0.2603 1
Echinococcus granulosus tumor protein p63 0.0751 0.0752 0.1566
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1226 0.1249 0.4795
Echinococcus multilocularis mothers against decapentaplegic 6 0.0058 0.0027 0.0057
Onchocerca volvulus 0.0091 0.0062 0.0181
Echinococcus granulosus nuclear receptor nhr 48 0.0071 0.0041 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0154 0.0128 0.0266
Echinococcus multilocularis smad 0.013 0.0102 0.0213
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0154 0.0128 0.0266
Brugia malayi hypothetical protein 0.0039 0.0007 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0162 0.0136 0.0136
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0244 0.0222 0.0461
Schistosoma mansoni smad 0.013 0.0102 0.0213
Brugia malayi Pre-SET motif family protein 0.0035 0.0003 0.0003
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0144 0.0117 0.0444
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Trichomonas vaginalis esterase, putative 0.008 0.005 0.0185
Echinococcus granulosus Tubulin beta 2C chain 0.252 0.2603 0.5419
Schistosoma mansoni thyroid hormone receptor 0.0306 0.0287 0.0598
Mycobacterium tuberculosis Probable reductase 0.0124 0.0096 0.0812
Echinococcus granulosus dihydrofolate reductase 0.005 0.0019 0.004
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0061
Loa Loa (eye worm) hypothetical protein 0.0123 0.0096 0.0095
Trichomonas vaginalis tubulin epsilon chain, putative 0.1836 0.1888 0.7249
Brugia malayi Histone deacetylase family protein 0.0317 0.0298 0.0298
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0021 0.0045
Loa Loa (eye worm) inositol-1 0.0073 0.0043 0.0043
Toxoplasma gondii LsmAD domain-containing protein 0.0289 0.0269 0.1027
Echinococcus granulosus thioredoxin glutathione reductase 0.0054 0.0024 0.0049
Leishmania major hypothetical protein, conserved 0.0867 0.0873 0.0871
Schistosoma mansoni opsin-like receptor 0.0154 0.0128 0.0266
Trypanosoma brucei beta tubulin 0.252 0.2603 0.2602
Brugia malayi MH2 domain containing protein 0.1902 0.1957 0.1957
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Echinococcus granulosus CREB binding protein 0.0082 0.0053 0.011
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Echinococcus granulosus somatostatin receptor 0.0154 0.0128 0.0266
Echinococcus granulosus lamin dm0 0.006 0.0029 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0041 0.0086
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0084 0.0055 0.0434
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Echinococcus multilocularis lamin dm0 0.006 0.0029 0.0061
Loa Loa (eye worm) hypothetical protein 0.0072 0.0042 0.0041
Schistosoma mansoni smad1 5 8 and 0.013 0.0102 0.0213
Brugia malayi amine oxidase, flavin-containing family protein 0.0084 0.0055 0.0055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0244 0.0222 0.0461
Brugia malayi Tubulin gamma chain 0.1405 0.1437 0.1437
Trichomonas vaginalis histone deacetylase, putative 0.0577 0.057 0.2183
Trichomonas vaginalis tubulin, putative 0.0795 0.0799 0.3062
Echinococcus granulosus muscleblind protein 0.0483 0.0472 0.0983
Schistosoma mansoni lipoxygenase 0.0084 0.0054 0.0113
Loa Loa (eye worm) hypothetical protein 0.0131 0.0104 0.0103
Echinococcus multilocularis neuropeptide s receptor 0.0682 0.068 0.1416
Brugia malayi Probable isocitrate dehydrogenase 0.0036 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.008 0.005 0.005
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.0146 0.0436
Schistosoma mansoni biogenic amine (5HT) receptor 0.4623 0.4804 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0041 0.0086
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0162 0.0136 0.0283
Loa Loa (eye worm) thioredoxin reductase 0.0054 0.0024 0.0023
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0036 0.0005 0.0004
Loa Loa (eye worm) histone deacetylase 7A 0.0317 0.0298 0.0298
Loa Loa (eye worm) histone deacetylase 0.0317 0.0298 0.0298
Echinococcus multilocularis neuropeptide receptor A26 0.0682 0.068 0.1416
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0146 0.0555
Echinococcus multilocularis glutamate receptor 2 0.0061 0.0031 0.0064
Trypanosoma brucei C-8 sterol isomerase, putative 0.959 1 1
Loa Loa (eye worm) tubulin beta-2A chain 0.252 0.2603 0.2603
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0162 0.0136 0.0136
Plasmodium falciparum protoporphyrinogen oxidase 0.0084 0.0055 0.0204
Trichomonas vaginalis tubulin alpha chain, putative 0.0795 0.0799 0.3062
Trypanosoma cruzi PAB1-binding protein , putative 0.0289 0.0269 0.0267
Mycobacterium ulcerans beta-lactamase 0.008 0.005 0.0394
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Loa Loa (eye worm) tubulin alpha-3 chain 0.1041 0.1056 0.1056
Loa Loa (eye worm) hypothetical protein 0.0144 0.0117 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.024 0.0916
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0017 0.0058
Brugia malayi Cation transporter family protein 0.0091 0.0062 0.0061
Echinococcus granulosus peptide allatostatin:somatostatin 0.0154 0.0128 0.0266
Brugia malayi Dopamine receptor 0.0154 0.0128 0.0127
Echinococcus granulosus histone deacetylase 1 0.0577 0.057 0.1186
Echinococcus granulosus sodium and chloride dependent glycine 0.0144 0.0117 0.0245
Echinococcus multilocularis CREB binding protein 0.009 0.0061 0.0127
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0039 0.0007 0.0007
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0097 0.0366
Loa Loa (eye worm) TYRA-2 protein 0.0154 0.0128 0.0127
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0091 0.0062 0.0128
Echinococcus granulosus tubulin gamma 1 chain 0.1405 0.1437 0.2991
Loa Loa (eye worm) hypothetical protein 0.0322 0.0304 0.0303
Trichomonas vaginalis tubulin alpha chain, putative 0.0795 0.0799 0.3062
Schistosoma mansoni nuclear hormone receptor 0.0162 0.0136 0.0283
Schistosoma mansoni transcription factor LCR-F1 0.0641 0.0638 0.1328
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0293 0.0273 0.0272
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0154 0.0128 0.0127
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0119 0.0092 0.0191
Loa Loa (eye worm) hypothetical protein 0.0144 0.0117 0.0117
Echinococcus multilocularis histone deacetylase 3 0.0577 0.057 0.1186
Brugia malayi p25-alpha family protein 0.042 0.0406 0.0406
Onchocerca volvulus 0.0154 0.0128 0.038
Echinococcus multilocularis 0.0084 0.0055 0.0115
Trichomonas vaginalis tubulin epsilon chain, putative 0.252 0.2603 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0162 0.0136 0.0283
Mycobacterium ulcerans hypothetical protein 0.008 0.005 0.0394
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0135 0.0108 0.0108
Echinococcus granulosus tubulin alpha chain 0.1836 0.1888 0.393
Echinococcus multilocularis tubulin alpha 3 chain 0.1836 0.1888 0.393
Echinococcus granulosus rhodopsin orphan GPCR 0.0154 0.0128 0.0266
Giardia lamblia Beta tubulin 0.252 0.2603 1
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Loa Loa (eye worm) MH1 domain-containing protein 0.013 0.0102 0.0102
Entamoeba histolytica tubulin gamma chain 0.1405 0.1437 0.5516
Schistosoma mansoni zinc finger protein 0.0071 0.0041 0.0086
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0577 0.057 0.2183
Trichomonas vaginalis chromobox protein, putative 0.008 0.005 0.0186
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.005 0.005
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0059 0.0028 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0162 0.0136 0.0136
Onchocerca volvulus Huntingtin homolog 0.0131 0.0104 0.0308
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0111 0.0083 0.0173
Echinococcus multilocularis transcription factor eb 0.0124 0.0096 0.0201
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0154 0.0128 0.0266
Giardia lamblia Histone deacetylase 0.0577 0.057 0.2183
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0867 0.0873 0.0871
Echinococcus granulosus transcription factor eb 0.0124 0.0096 0.0201
Echinococcus granulosus Tubulin beta 2C chain 0.252 0.2603 0.5419
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0003 0.0007
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Plasmodium vivax ataxin-2 like protein, putative 0.0289 0.0269 0.1027
Onchocerca volvulus 0.0848 0.0854 0.2564
Loa Loa (eye worm) hypothetical protein 0.0084 0.0055 0.0055
Brugia malayi Serotonin receptor 0.0154 0.0128 0.0127
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Echinococcus multilocularis Tubulin alpha 1 chain 0.1836 0.1888 0.393
Loa Loa (eye worm) nuclear receptor NHR-67 0.0071 0.0041 0.0041
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0036 0.0005 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.0024 0.0021
Brugia malayi G-protein coupled receptor 0.0154 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.0289 0.0269 0.0269
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0088 0.0059 0.0218
Entamoeba histolytica tubulin alpha-1 chain 0.1836 0.1888 0.7249
Echinococcus multilocularis neuropeptide Y receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) hypothetical protein 0.0091 0.0062 0.0061
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Brugia malayi CXXC zinc finger family protein 0.0033 0.0001 0.0001
Trypanosoma brucei zeta tubulin 0.061 0.0605 0.0603
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Chlamydia trachomatis dihydrofolate reductase 0.005 0.0019 0.1035
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0061 0.003 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0154 0.0128 0.0266
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0145 0.0118 0.0246
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0061 0.003 0.0028
Brugia malayi beta-tubulin, identical 0.252 0.2603 0.2603
Leishmania major alpha tubulin 0.1836 0.1888 0.1886
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0162 0.0136 0.0405
Treponema pallidum sodium- and chloride- dependent transporter 0.0848 0.0854 1
Onchocerca volvulus 0.0154 0.0128 0.038
Loa Loa (eye worm) hypothetical protein 0.006 0.0029 0.0029
Echinococcus multilocularis G protein coupled receptor 139 0.0154 0.0128 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.061 0.0605 0.2318
Plasmodium falciparum alpha tubulin 2 0.1836 0.1888 0.7249
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0036 0.0005 0.0004
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0043 0.0089
Brugia malayi Intermediate filament tail domain containing protein 0.006 0.0029 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0097 0.0366
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.01 0.0072 0.0269
Trichomonas vaginalis tubulin gamma chain, putative 0.252 0.2603 1
Brugia malayi hypoxia-induced factor 1 0.0173 0.0148 0.0147
Echinococcus granulosus chromobox protein 1 0.008 0.005 0.0105
Echinococcus granulosus mothers against decapentaplegic 6 0.0058 0.0027 0.0057
Trypanosoma brucei trypanothione reductase 0.0054 0.0024 0.0021
Echinococcus multilocularis tubulin beta 1 chain 0.252 0.2603 0.5419
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0089 0.006 0.0124
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.061 0.0605 1
Loa Loa (eye worm) hypothetical protein 0.0162 0.0136 0.0136
Schistosoma mansoni inositol monophosphatase 0.0073 0.0043 0.009
Echinococcus granulosus thymidylate synthase 0.0123 0.0096 0.02
Loa Loa (eye worm) tubulin alpha 2 0.0431 0.0418 0.0417
Echinococcus granulosus histone deacetylase 8 0.02 0.0176 0.0367
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0244 0.0222 0.0461
Loa Loa (eye worm) tubulin gamma chain 0.1405 0.1437 0.1437
Onchocerca volvulus 0.0322 0.0304 0.0909
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0014 0.0045
Trypanosoma cruzi histone deacetylase, putative 0.0317 0.0298 0.0296
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.024 0.0916
Trypanosoma cruzi Emopamil binding protein, putative 0.0867 0.0873 0.0871
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0848 0.0854 0.0854
Echinococcus multilocularis fmrfamide receptor 0.0154 0.0128 0.0266
Loa Loa (eye worm) tubulin alpha-2 chain 0.1836 0.1888 0.1887
Brugia malayi beta-lactamase 0.008 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0039 0.0007 0.0007
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0138 0.0111 0.094
Schistosoma mansoni tubulin subunit alpha 0.061 0.0605 0.126
Loa Loa (eye worm) hypothetical protein 0.0144 0.0117 0.0117
Brugia malayi hypothetical protein 0.0154 0.0128 0.0127
Schistosoma mansoni metabotropic glutamate receptor 0.0039 0.0007 0.0015
Toxoplasma gondii endonuclease IV APN 0.0088 0.0059 0.0218
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0299 0.028 0.0278
Schistosoma mansoni histone deacetylase hda2 0.02 0.0176 0.0367
Schistosoma mansoni growth hormone secretagogue receptor 0.0154 0.0128 0.0266
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0154 0.0128 0.0266
Trypanosoma brucei alpha tubulin 0.1836 0.1888 0.1886
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0299 0.028 0.0582
Onchocerca volvulus 0.0048 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.008 0.005 0.005
Brugia malayi Glutamate receptor 1 precursor 0.0111 0.0083 0.0083
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0144 0.0117 0.0444
Entamoeba histolytica hypothetical protein 0.0641 0.0638 0.2444
Mycobacterium tuberculosis Probable lipase LipE 0.008 0.005 0.0404
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0041 0.0086
Loa Loa (eye worm) histone deacetylase 1 0.0577 0.057 0.057
Echinococcus granulosus tubulin alpha 1C chain 0.1836 0.1888 0.393
Loa Loa (eye worm) hypothetical protein 0.0848 0.0854 0.0854
Brugia malayi Inositol-1 0.0073 0.0043 0.0043
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.3213 0.3329 1
Trypanosoma cruzi histone deacetylase, putative 0.02 0.0176 0.0174
Schistosoma mansoni glutamate receptor NMDA 0.015 0.0124 0.0257
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0154 0.0128 0.0127
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0428 0.0414 0.0414
Brugia malayi follicle stimulating hormone receptor 0.0418 0.0404 0.0404
Schistosoma mansoni glutamate receptor NMDA 0.0111 0.0083 0.0173
Loa Loa (eye worm) hypothetical protein 0.0084 0.0055 0.0055
Trypanosoma cruzi tubulin delta chain 0.061 0.0605 0.0603
Brugia malayi Histone deacetylase family protein 0.0317 0.0298 0.0298
Mycobacterium ulcerans thymidylate synthase 0.0123 0.0096 0.0768
Leishmania major histone deacetylase, putative 0.0577 0.057 0.0568
Schistosoma mansoni Smad4 0.013 0.0102 0.0213
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0058 0.0027 0.0078
Echinococcus multilocularis serotonin receptor 0.2381 0.2458 0.5116
Trypanosoma brucei alpha tubulin, putative 0.0795 0.0799 0.0797
Echinococcus multilocularis beta tubulin 0.252 0.2603 0.5419
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0144 0.0117 0.0245
Echinococcus granulosus survival motor neuron protein 1 0.024 0.0217 0.0452
Brugia malayi nuclear receptor RXR 0.0071 0.0041 0.0041
Echinococcus granulosus tachykinin peptides receptor 99D 0.0154 0.0128 0.0266
Echinococcus granulosus nmda type glutamate receptor 0.0283 0.0263 0.0547
Toxoplasma gondii ABC1 family protein 0.008 0.005 0.0185
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Echinococcus multilocularis fmrfamide receptor 0.0154 0.0128 0.0266
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0154 0.0128 0.0266
Onchocerca volvulus 0.0071 0.0041 0.012
Loa Loa (eye worm) hypothetical protein 0.0848 0.0854 0.0854
Leishmania major beta tubulin 0.252 0.2603 0.2602
Echinococcus granulosus tm gpcr rhodopsin 0.0154 0.0128 0.0266
Echinococcus multilocularis mothers against decapentaplegic 5 0.013 0.0102 0.0213
Loa Loa (eye worm) hypothetical protein 0.0059 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.011 0.0082 0.0081
Echinococcus multilocularis NMDA receptor 0.0089 0.006 0.0124
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0091 0.0062 0.0128
Echinococcus granulosus lysine specific histone demethylase 1A 0.0084 0.0055 0.0115
Leishmania major beta tubulin 0.252 0.2603 0.2602
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.005 0.0019 0.013
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0014 0.0045
Echinococcus granulosus atrial natriuretic peptide receptor 0.0039 0.0007 0.0015
Plasmodium vivax tubulin alpha chain, putative 0.1836 0.1888 0.7249
Toxoplasma gondii histone deacetylase HDAC2 0.0577 0.057 0.2183
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0002 0.0002
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0084 0.0055 0.0204
Entamoeba histolytica tubulin alpha chain, putative 0.1836 0.1888 0.7249
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0156 0.0592
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.008 0.005 0.0404
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0262 0.024 0.024
Trypanosoma cruzi epsilon tubulin, putative 0.1405 0.1437 0.1435
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.024 0.0218 0.0217
Trichomonas vaginalis tubulin beta chain, putative 0.252 0.2603 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0007 0.0007
Echinococcus granulosus receptor type guanylyl cyclase 0.0039 0.0007 0.0015
Echinococcus granulosus glutamate receptor subunit protein glur 0.0089 0.006 0.0124
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0091 0.0062 0.0128
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0061 0.003 0.0063
Trypanosoma brucei epsilon tubulin 0.1405 0.1437 0.1435
Loa Loa (eye worm) hypothetical protein 0.0154 0.0128 0.0127
Plasmodium vivax thioredoxin reductase, putative 0.0054 0.0024 0.0083
Brugia malayi Pre-SET motif family protein 0.024 0.0218 0.0217
Leishmania major UDP-galactopyranose mutase 0.0084 0.0055 0.0053
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0194 0.017 0.1968
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0162 0.0136 0.0283
Brugia malayi vesicular acetylcholine transporter unc-17 0.3213 0.3329 0.3328
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.005 0.0048
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.0021 0.0045

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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