Detailed information for compound 869324

Basic information

Technical information
  • TDR Targets ID: 869324
  • Name: 4-acetyl-6-chloro-N-(2,5-difluorophenyl)-2,3- dihydro-1,4-benzoxazine-7-sulfonamide
  • MW: 402.8 | Formula: C16H13ClF2N2O4S
  • H donors: 1 H acceptors: 3 LogP: 2.38 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(c(c1)NS(=O)(=O)c1cc2OCCN(c2cc1Cl)C(=O)C)F
  • InChi: 1S/C16H13ClF2N2O4S/c1-9(22)21-4-5-25-15-8-16(11(17)7-14(15)21)26(23,24)20-13-6-10(18)2-3-12(13)19/h2-3,6-8,20H,4-5H2,1H3
  • InChiKey: XEQUCBBRKNGSLJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-chloro-N-(2,5-difluorophenyl)-4-ethanoyl-2,3-dihydro-1,4-benzoxazine-7-sulfonamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0123 0.0159 0.0156
Leishmania major hypothetical protein, conserved 0.0039 0.0027 0.007
Brugia malayi hypothetical protein 0.0044 0.0034 0.0245
Brugia malayi hypothetical protein 0.0049 0.0043 0.0304
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0033 0.0018 0.0026
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.035 0.0518 0.1293
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0053 0.0049 0.0078
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0053 0.0049 0.0047
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.001 0.0024
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0191 0.0476
Loa Loa (eye worm) hypothetical protein 0.0504 0.0759 0.4834
Loa Loa (eye worm) hypothetical protein 0.0028 0.001 0.0062
Leishmania major hypothetical protein, unknown function 0.0123 0.0159 0.043
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0011 0.0009
Loa Loa (eye worm) phosphatidylinositol 3 0.0209 0.0295 0.188
Echinococcus multilocularis peregrin 0.008 0.0092 0.009
Trichomonas vaginalis ap endonuclease, putative 0.0103 0.0128 0.0319
Trichomonas vaginalis DNA helicase recq, putative 0.0086 0.0101 0.0253
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0268 0.0669
Echinococcus multilocularis PHD finger protein rhinoceros 0.0062 0.0064 0.0061
Echinococcus granulosus lamin dm0 0.006 0.006 0.0058
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0105 0.0131 0.1497
Onchocerca volvulus 0.0096 0.0117 0.0733
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0073 0.0081 0.0576
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0028 0.001 0.0024
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0154 0.0209 0.0206
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0112 0.0143 0.014
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0051 0.0262
Leishmania major casein kinase II, putative 0.0143 0.0191 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.0535 0.0808 0.2017
Brugia malayi jmjC domain containing protein 0.0141 0.0187 0.1334
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.2563 0.4004 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0003 0.0015
Brugia malayi Steroid receptor seven-up type 2 0.0093 0.0111 0.0795
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0064 0.0066 0.0164
Echinococcus multilocularis muscleblind protein 0.032 0.047 0.0467
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.0159 0.101
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0204 0.0287 0.0285
Entamoeba histolytica deoxycytidyl transferase, putative 0.0112 0.0143 0.0352
Echinococcus multilocularis cpg binding protein 0.011 0.0139 0.0136
Brugia malayi jmjC domain containing protein 0.0141 0.0187 0.1334
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.014 0.0185 0.1181
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0003 0.002
Echinococcus multilocularis thyroid hormone receptor alpha 0.0093 0.0111 0.0109
Brugia malayi serine/threonine-protein kinase plk-2 0.02 0.0281 0.2002
Loa Loa (eye worm) hypothetical protein 0.0062 0.0063 0.04
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0103 0.0128 0.0315
Brugia malayi hypothetical protein 0.0049 0.0043 0.0304
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0007 0.007
Trypanosoma brucei glucosidase, putative 0.0038 0.0026 0.0235
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0144 0.036
Loa Loa (eye worm) hypothetical protein 0.0049 0.0043 0.0271
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0206 0.0289 0.0478
Schistosoma mansoni DNA helicase recq5 0.0073 0.0081 0.013
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0014 0.0009
Echinococcus multilocularis musashi 0.006 0.006 0.0058
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0123 0.0159 0.0392
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.036 0.0533 0.38
Loa Loa (eye worm) RecQ helicase 0.0086 0.0101 0.0645
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0051 0.0262
Loa Loa (eye worm) glutaminase 0.087 0.1336 0.8506
Brugia malayi photoreceptor-specific nuclear receptor 0.0093 0.0111 0.0795
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0073 0.0081 0.2751
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0144 0.0918
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0268 0.0669
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0191 0.0476
Entamoeba histolytica hypothetical protein 0.0123 0.0159 0.0392
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0103 0.0128 0.0125
Loa Loa (eye worm) phosphatidylinositol 3 0.0546 0.0826 0.5258
Trypanosoma brucei unspecified product 0.0178 0.0246 0.2394
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0122 0.1176
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0003 0.0006
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0026 0.0064
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0269 0.0389 0.0387
Entamoeba histolytica serine/threonine protein kinase, putative 0.02 0.0281 0.0697
Echinococcus granulosus methyl CpG binding domain protein 2 0.0073 0.008 0.0078
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0054 0.0051 0.0318
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0318 0.0466 0.1274
Loa Loa (eye worm) hypothetical protein 0.005 0.0045 0.0285
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0123 0.0159 0.0156
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.0494 0.0818
Echinococcus granulosus RUN 0.0044 0.0035 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0578 0.0876 0.2187
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0164 0.0224 0.2568
Brugia malayi CXXC zinc finger family protein 0.0096 0.0117 0.0837
Brugia malayi beta-NAC-like protein 0.0077 0.0086 0.0616
Brugia malayi Csnk2b protein 0.0038 0.0026 0.0183
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0332 0.0488 0.1219
Schistosoma mansoni hypothetical protein 0.0065 0.0069 0.011
Schistosoma mansoni phosphatidylserine receptor 0.0141 0.0187 0.0307
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0137 0.0181 0.0178
Trichomonas vaginalis DNA polymerase eta, putative 0.02 0.028 0.07
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0044 0.0034 0.0245
Loa Loa (eye worm) hypothetical protein 0.0093 0.0111 0.071
Loa Loa (eye worm) hypothetical protein 0.0303 0.0442 0.2817
Schistosoma mansoni myelin transcription factor 1 myt1 0.0062 0.0063 0.01
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0064 0.0066 0.0164
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.0123 0.0881
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0093 0.0111 0.0109
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0035 0.0032
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0014 0.042
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0114 0.0326
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2563 0.4004 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.0253 0.1609
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0019 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0554 0.0838 0.2093
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0141 0.0187 0.0537
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0026 0.006
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0103 0.0128 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0554 0.0838 0.2093
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Schistosoma mansoni bromodomain containing protein 0.0284 0.0413 0.0684
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0281 0.0701
Plasmodium vivax hypothetical protein 0.0123 0.0159 0.5408
Leishmania major DNA damage repair protein, putative 0.0035 0.002 0.0052
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0123 0.0159 0.5408
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0027 0.0249
Brugia malayi Pre-SET motif family protein 0.0912 0.1402 1
Echinococcus granulosus cyclin dependent kinase 19 0.014 0.0185 0.0183
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0144 0.0744
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0064 0.0066 0.0743
Brugia malayi Intermediate filament tail domain containing protein 0.006 0.006 0.0429
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0144 0.0918
Trichomonas vaginalis PIKK family atypical protein kinase 0.0355 0.0525 0.1312
Schistosoma mansoni cpg binding protein 0.011 0.0139 0.0227
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0096 0.9881
Echinococcus multilocularis cyclin dependent kinase 19 0.014 0.0185 0.0183
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0034 0.0053
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0097 0.3303
Entamoeba histolytica hypothetical protein 0.0118 0.0152 0.0375
Schistosoma mansoni DNA helicase recq1 0.0073 0.0081 0.013
Echinococcus multilocularis histone acetyltransferase MYST2 0.0062 0.0063 0.006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0003 0.0003
Plasmodium vivax basic transcription factor 3b, putative 0.0077 0.0086 0.2867
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0103 0.0128 0.2499
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Giardia lamblia Casein kinase II beta chain 0.0038 0.0026 0.003
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0103 0.0128 0.0286
Echinococcus multilocularis nuclear receptor nhr 48 0.0044 0.0034 0.0032
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0785 0.1202 0.3002
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0083 0.0096 0.0494
Schistosoma mansoni z-protein (S1r protein) 0.003 0.0013 0.0017
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0015 0.0093
Echinococcus granulosus FTZ F1 alpha 0.0093 0.0111 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0204 0.0287 0.0717
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0785 0.1202 0.2999
Schistosoma mansoni lipoxygenase 0.0115 0.0147 0.0241
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0587 0.0891 0.0888
Loa Loa (eye worm) hypothetical protein 0.0637 0.0969 0.6169
Echinococcus granulosus protein kinase shaggy 0.0053 0.0049 0.0047
Schistosoma mansoni rab6-interacting 0.0044 0.0035 0.0054
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Echinococcus multilocularis FTZ F1 alpha 0.0093 0.0111 0.0109
Loa Loa (eye worm) phosphatidylinositol 3 0.1018 0.157 1
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0573 0.0868 0.0866
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0191 0.0476
Brugia malayi ImpB/MucB/SamB family protein 0.0141 0.0188 0.1343
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0164 0.0224 0.0645
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0051 0.0048
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Echinococcus multilocularis dnaJ subfamily B 0.1372 0.2128 0.2126
Echinococcus multilocularis serine protein kinase ATM 0.0327 0.0481 0.0479
Trichomonas vaginalis PIKK family atypical protein kinase 0.0597 0.0906 0.2263
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0024 0.0003 0.0016
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0785 0.1202 0.3477
Onchocerca volvulus 0.0054 0.0051 0.0318
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0123 0.0159 0.0454
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.009 0.0108 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0554 0.0838 0.2093
Loa Loa (eye worm) nuclear hormone receptor 0.0044 0.0034 0.0219
Schistosoma mansoni zinc finger protein 0.0097 0.0119 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.028 0.2729
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0137 0.0181 0.0933
Schistosoma mansoni alpha-glucosidase 0.0148 0.0199 0.0327
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0508 0.0766 0.4878
Leishmania major hypothetical protein, conserved 0.2337 0.3647 1
Loa Loa (eye worm) hypothetical protein 0.0491 0.074 0.4712
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0026 0.006
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0205 0.0289 0.0722
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0205 0.0289 0.0287
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0123 0.0159 0.5458
Loa Loa (eye worm) hypothetical protein 0.0573 0.0868 0.553
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0597 0.0906 0.2259
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0144 0.0142
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0546 0.0826 0.226
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0096 0.9881
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0205 0.0289 0.0287
Echinococcus multilocularis Polycystic kidney disease protein 0.0044 0.0035 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0141 0.0187 0.1191
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.0026 0.0735
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0064 0.0066 0.0627
Loa Loa (eye worm) hypothetical protein 0.0205 0.0289 0.184
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.0116
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0164 0.0224 0.061
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0096 0.1085
Echinococcus granulosus regulator of G protein signaling 7 0.003 0.0013 0.001
Plasmodium falciparum basic transcription factor 3b, putative 0.0077 0.0086 0.2944
Leishmania major DNA polymerase eta, putative 0.0064 0.0066 0.0177
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.002 0.0017
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0027 0.014
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0426 0.1064
Echinococcus granulosus jumonji domain containing protein 0.0087 0.0102 0.0099
Brugia malayi intermediate filament protein 0.006 0.006 0.0429
Giardia lamblia Kinase, CMGC GSK 0.0053 0.0049 0.0089
Schistosoma mansoni hypothetical protein 0.0222 0.0316 0.0522
Brugia malayi Protein kinase domain containing protein 0.014 0.0185 0.1323
Onchocerca volvulus 0.006 0.006 0.0376
Mycobacterium tuberculosis Conserved hypothetical protein 0.0354 0.0523 0.2696
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0064 0.0066 0.0164
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0073 0.008 0.0078
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0102 0.0126 0.0124
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0597 0.0906 0.2259
Trypanosoma brucei DNA polymerase kappa, putative 0.0134 0.0177 0.1715
Loa Loa (eye worm) bromodomain containing protein 0.0084 0.0097 0.0618
Mycobacterium ulcerans glutaminase 0.087 0.1336 0.6889
Brugia malayi hypothetical protein 0.017 0.0234 0.1668
Trichomonas vaginalis PIKK family atypical protein kinase 0.0573 0.0868 0.2168
Loa Loa (eye worm) nuclear receptor NHR-67 0.0044 0.0034 0.0219
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0508 0.0766 0.2213
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0003 0.0015
Echinococcus multilocularis 0.0123 0.0159 0.0156
Echinococcus granulosus transcription factor Dp 1 0.0294 0.0429 0.0426
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0026 0.0023
Mycobacterium ulcerans lipase LipD 0.0039 0.0027 0.014
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0426 0.1064
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Mycobacterium tuberculosis Conserved protein 0.0039 0.0027 0.014
Brugia malayi steroid hormone receptor 0.0093 0.0111 0.0795
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0066 0.0164
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0003 0.0003
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.002 0.0217
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.0359 0.1853
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2563 0.4004 1
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0335 0.0494 0.0491
Entamoeba histolytica recQ family DNA helicase 0.0037 0.0024 0.0056
Schistosoma mansoni hypothetical protein 0.0062 0.0064 0.0102
Plasmodium vivax JmjC domain containing protein 0.0141 0.0187 0.6409
Schistosoma mansoni nuclear receptor 0.0044 0.0034 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0093 0.0111 0.0795
Schistosoma mansoni transcription factor LCR-F1 0.0118 0.0152 0.0248
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0059 0.0058 0.0093
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0103 0.0128 0.0365
Plasmodium falciparum phd finger protein, putative 0.0062 0.0064 0.2154
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0206 0.0289 0.0478
Echinococcus granulosus nuclear receptor nhr 48 0.0044 0.0034 0.0032
Schistosoma mansoni jumonji domain containing protein 0.0141 0.0187 0.0307
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0097 0.323
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0073 0.0081 0.0078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2563 0.4004 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0133 0.0174 0.0172
Mycobacterium ulcerans DNA polymerase IV 0.02 0.028 0.1447
Onchocerca volvulus Glucosylceramidase homolog 0.0192 0.0268 0.1673
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0312 0.0457 0.3262
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0027 0.0784
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0003 0.0015
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0093 0.0111 0.0109
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.003 0.0013 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.028 0.2729
Echinococcus granulosus PHD finger protein rhinoceros 0.0062 0.0064 0.0061
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0123 0.0159 0.0454
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0164 0.0224 0.0645
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.028 0.2729
Schistosoma mansoni lamin 0.006 0.006 0.0096
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0154 0.0208 0.0205
Loa Loa (eye worm) gastrulation defective protein 1 0.0136 0.018 0.1146
Brugia malayi Peptidase family C54 containing protein 0.0059 0.0058 0.0416
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0281 0.0701
Trichomonas vaginalis PIKK family atypical protein kinase 0.0573 0.0868 0.2168
Plasmodium vivax hypothetical protein, conserved 0.0123 0.0159 0.5408
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0103 0.0128 0.1234
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0049 0.0043 0.0067
Echinococcus multilocularis dna polymerase eta 0.0141 0.0188 0.0186
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0048 0.004 0.1253
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0053 0.0133
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0298
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0028 0.001 0.0012
Schistosoma mansoni methyl-cpg binding protein mbd 0.0073 0.008 0.013
Loa Loa (eye worm) hypothetical protein 0.0044 0.0035 0.0222
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0018 0.0016
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0508 0.0766 0.5463
Echinococcus multilocularis SAM and MBT domain containing protein 0.0054 0.0051 0.0048
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0671 0.1023 0.2959
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0093 0.0111 0.0795
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0058 0.0146
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0671 0.1023 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.02 0.028 0.0807
Trypanosoma brucei transcription factor BTF3, putative 0.0077 0.0086 0.0828
Loa Loa (eye worm) hypothetical protein 0.0034 0.0019 0.0122
Brugia malayi PHD-finger family protein 0.012 0.0155 0.1103
Echinococcus granulosus serine:threonine protein kinase PLK1 0.02 0.0281 0.0278
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0137 0.0181 0.0297
Trypanosoma cruzi casein kinase II, putative 0.0143 0.0191 0.0547
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0093 0.0111 0.0795
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Schistosoma mansoni lozenge 0.0063 0.0065 0.0104
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0011 0.0008
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0597 0.0906 0.2481
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0014 0.0034
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0094 0.0114 0.1102
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0671 0.1023 0.2959
Loa Loa (eye worm) hypothetical protein 0.0049 0.0043 0.0271
Echinococcus granulosus histone lysine methyltransferase setb 0.0206 0.0289 0.0287
Echinococcus granulosus dna polymerase eta 0.0141 0.0188 0.0186
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0025 0.0176
Echinococcus granulosus tumor protein p63 0.0353 0.0521 0.0519
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.0159 0.101
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0043 0.0034 0.0084
Echinococcus multilocularis ubiquitin specific protease 41 0.0204 0.0287 0.0285
Brugia malayi hypoxia-induced factor 1 0.0157 0.0213 0.1519
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.028 0.2729
Echinococcus granulosus histone acetyltransferase KAT2B 0.0315 0.0461 0.0459
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0137 0.0181 0.0933
Onchocerca volvulus 0.0105 0.0131 0.0817
Giardia lamblia Histone acetyltransferase GCN5 0.0087 0.0103 0.0223
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0011 0.0008
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0383
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0044 0.0034 0.0215
Leishmania major hypothetical protein, conserved 0.0141 0.0187 0.0508
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0173
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0204 0.0287 0.0826
Loa Loa (eye worm) hypothetical protein 0.0164 0.0224 0.1428
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0016 0.0116
Echinococcus granulosus expressed conserved protein 0.0085 0.01 0.0097
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0312 0.0457 0.0455
Brugia malayi nuclear receptor RXR 0.0044 0.0034 0.0245
Brugia malayi N-terminal motif family protein 0.0205 0.0289 0.2061
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0014 0.0034
Echinococcus multilocularis lamin 0.006 0.006 0.0058
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0053 0.0049 0.0047
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0785 0.1202 0.3002
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0014 0.0034
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0047 0.0074
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0003 0.002
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0597 0.0906 0.0904
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.028 0.2729
Schistosoma mansoni hypothetical protein 0.0353 0.0522 0.0866
Trichomonas vaginalis PIKK family atypical protein kinase 0.0535 0.0808 0.2017
Onchocerca volvulus 0.006 0.006 0.0376
Schistosoma mansoni cpg binding protein 0.0096 0.0117 0.0191
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0026 0.0064
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0205 0.0289 1
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0049 0.0119
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0112 0.0143 0.014
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0049 0.0043 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0018
Echinococcus multilocularis ecdysone induced protein 78C 0.0093 0.0111 0.0109
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0093 0.0112 0.011
Schistosoma mansoni nuclear receptor nhr-48 0.0044 0.0034 0.0053
Brugia malayi Casein kinase II, alpha chain 0.0143 0.0191 0.136
Brugia malayi Nuclear hormone receptor E75 0.0044 0.0034 0.0245
Trypanosoma brucei unspecified product 0.0078 0.0088 0.0842
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Plasmodium falciparum histone acetyltransferase GCN5 0.0087 0.0103 0.3522
Echinococcus multilocularis phd:f box containing protein 0.0141 0.0187 0.0185
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0124 0.0309
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0205 0.0289 0.3317
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0028 0.001 0.0007
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0144 0.0744
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0086 0.0215
Echinococcus granulosus geminin 0.0353 0.0522 0.052
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0073 0.0081 0.0078
Brugia malayi hypothetical protein 0.0044 0.0035 0.0249
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0597 0.0906 0.8852
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0123 0.0159 0.1536
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0044 0.0034 0.0032
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0205 0.0289 0.3317
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.001 0.0194
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0037 0.0024 0.0065
Brugia malayi Bloom's syndrome protein homolog 0.0086 0.0101 0.0722
Echinococcus granulosus transcription factor btf3 0.0077 0.0086 0.0084
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0026 0.0164
Leishmania major phosphatidylinositol kinase, putative 0.0123 0.0159 0.043
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0173
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0123 0.0159 0.026
Entamoeba histolytica hypothetical protein 0.0658 0.1003 0.2501
Echinococcus granulosus lysine specific demethylase 5A 0.0541 0.0818 0.0816
Schistosoma mansoni cpg binding protein 0.011 0.0139 0.0227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0093 0.0111 0.071
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0597 0.0906 0.2619
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0115 0.0147 0.042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0133 0.0174 0.0286
Brugia malayi CHD4 protein 0.0025 0.0006 0.004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0118 0.0152 0.0149
Schistosoma mansoni loxhd1 0.0044 0.0035 0.0054
Schistosoma mansoni hypothetical protein 0.0123 0.0159 0.026
Echinococcus granulosus single minded 2 0.0038 0.0025 0.0022
Echinococcus multilocularis dna polymerase kappa 0.02 0.028 0.0278
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0087 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0535 0.0808 0.2017
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0164 0.0224 0.1157
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0093 0.0111 0.0795
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0018 0.0016
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0049 0.0119
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0205 0.0289 0.0833
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.001 0.0301
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0143 0.0191 0.6535
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.002 0.0054
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0027 0.0068
Brugia malayi beta-lactamase family protein 0.0039 0.0027 0.0193
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0073 0.0081 0.0913
Loa Loa (eye worm) hypothetical protein 0.0196 0.0274 0.1746
Trichomonas vaginalis ap endonuclease, putative 0.0103 0.0128 0.0319
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.0159 0.1131
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0205 0.0289 0.0478
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0035 0.0032
Echinococcus granulosus voltage dependent calcium channel 0.0033 0.0018 0.0016
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0205 0.0288 0.083
Giardia lamblia PHD finger protein 15 0.0062 0.0064 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0093 0.0111 0.0795
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0073 0.0081 0.0576
Trypanosoma cruzi target of rapamycin kinase 3 0.0578 0.0876 0.2532
Echinococcus multilocularis transcription factor btf3 0.0077 0.0086 0.0084
Mycobacterium tuberculosis Conserved protein 0.0039 0.0027 0.014
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Schistosoma mansoni glutaminase 0.087 0.1336 0.2221
Entamoeba histolytica hypothetical protein 0.0327 0.0481 0.1198
Loa Loa (eye worm) hypothetical protein 0.0059 0.0058 0.0372
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0014 0.042
Loa Loa (eye worm) hypothetical protein 0.0054 0.0051 0.0325
Trypanosoma cruzi DNA polymerase eta, putative 0.0141 0.0188 0.054
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0027 0.014
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0027 0.0068
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2563 0.4004 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0093 0.0111 0.071
Echinococcus granulosus regulator of G protein signaling 7 0.003 0.0013 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0284 0.0709
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0597 0.0906 0.0904
Mycobacterium ulcerans endonuclease IV 0.0083 0.0097 0.0499
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.0159 0.1131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0554 0.0838 0.2093
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0038 0.0026 0.0235
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0335 0.0494 0.0491
Trichomonas vaginalis PIKK family atypical protein kinase 0.0597 0.0906 0.2263
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0051 0.0048
Echinococcus multilocularis high voltage activated calcium channel beta 0.009 0.0108 0.0106
Brugia malayi nuclear receptor NHR-88 0.0093 0.0111 0.0795
Schistosoma mansoni hypothetical protein 0.0044 0.0035 0.0054
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0093 0.0112 0.0182
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0144 0.0356
Leishmania major phosphatidylinositol 4-kinase, putative 0.0123 0.0159 0.043
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0597 0.0906 0.1506
Brugia malayi Probable ClpP-like protease 0.0083 0.0096 0.0682
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.028 0.2729
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0064 0.0066 0.0627
Leishmania major phosphatidylinositol kinase related protein, putative 0.0138 0.0183 0.0496
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0053 0.0133
Echinococcus multilocularis expressed protein 0.0389 0.0579 0.0577
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1145 0.1769 0.1767
Loa Loa (eye worm) hypothetical protein 0.0093 0.0111 0.071
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0003 0.0006
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0335 0.0494 0.3143
Toxoplasma gondii ABC1 family protein 0.0039 0.0027 0.0293
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0122 0.1176
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0123 0.0159 0.0396
Echinococcus multilocularis jumonji domain containing 1A 0.0141 0.0187 0.0185
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0093 0.0111 0.0109
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0026 0.006
Loa Loa (eye worm) hypothetical protein 0.0037 0.0024 0.0155
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0019 0.0046
Loa Loa (eye worm) steroid hormone receptor 0.0093 0.0111 0.071
Schistosoma mansoni hypothetical protein 0.0353 0.0522 0.0866
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0027 0.0074
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0144 0.1395
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0103 0.0128 0.4387
Loa Loa (eye worm) hypothetical protein 0.0204 0.0287 0.1828
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0209 0.0295 0.085
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0103 0.0128 0.0346
Schistosoma mansoni inositol monophosphatase 0.0164 0.0224 0.0369
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0003 0.0003
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0093 0.0111 0.0181
Brugia malayi jmjC domain containing protein 0.0141 0.0187 0.1334
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0161 0.0219 0.2126
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0186 0.0259 0.185
Toxoplasma gondii target of rapamycin (TOR), putative 0.0573 0.0868 1
Loa Loa (eye worm) calcium channel 0.0033 0.0018 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0284 0.0709
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0335 0.0494 0.3521
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0137 0.0181 0.0492
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0059 0.0058 0.0155
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0144 0.0356
Schistosoma mansoni intermediate filament proteins 0.006 0.006 0.0096
Brugia malayi acetyltransferase, GNAT family protein 0.0334 0.0491 0.3505
Echinococcus granulosus peregrin 0.008 0.0092 0.009
Toxoplasma gondii endonuclease IV APN 0.0083 0.0097 0.1096
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.006
Trypanosoma brucei DNA polymerase IV, putative 0.02 0.028 0.2729
Trichomonas vaginalis PIKK family atypical protein kinase 0.0578 0.0876 0.2187
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.0026 0.0161
Toxoplasma gondii exonuclease III APE 0.0103 0.0128 0.1455
Trypanosoma cruzi DNA polymerase kappa, putative 0.02 0.028 0.0807
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0508 0.0766 0.0764
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0025 0.0127
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Schistosoma mansoni jumonji/arid domain-containing protein 0.0541 0.0818 0.1359
Loa Loa (eye worm) jmjC domain-containing protein 0.0541 0.0818 0.5209
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0144 0.0236
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0235 0.0335 0.0333
Onchocerca volvulus 0.0024 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0102 0.0126 0.0206
Entamoeba histolytica hypothetical protein 0.0123 0.0159 0.0392
Mycobacterium ulcerans DNA polymerase IV 0.02 0.028 0.1447
Onchocerca volvulus 0.0053 0.0049 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0578 0.0876 0.2187
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0024 0.0036
Entamoeba histolytica hypothetical protein 0.0077 0.0086 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0066 0.0164
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0204 0.0287 0.0285
Trypanosoma brucei chrX additional, unordered contigs 0.0035 0.002 0.0184
Schistosoma mansoni zinc finger protein 0.0065 0.0069 0.011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0112 0.0143 0.0736
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0141 0.0187 0.1814
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0038 0.0026 0.0066
Echinococcus granulosus zinc finger protein 0.0097 0.0119 0.0116
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.005 0.0044 0.028
Toxoplasma gondii CMGC kinase, CK2 family 0.0143 0.0191 0.218
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0093 0.0111 0.0181
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.2563 0.4004 1
Schistosoma mansoni survival motor neuron protein 0.01 0.0123 0.0201
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0508 0.0766 0.1909
Echinococcus granulosus mixed lineage leukemia protein mll 0.0029 0.0011 0.0008
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0036 0.0022 0.0605
Loa Loa (eye worm) hypothetical protein 0.0093 0.0111 0.071
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0049 0.0043 0.0067
Loa Loa (eye worm) acetyltransferase 0.0334 0.0491 0.3129
Schistosoma mansoni nuclear receptor 0.0044 0.0034 0.0053
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0382 0.0567 0.094
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0093 0.0111 0.0109
Entamoeba histolytica casein kinase, putative 0.0143 0.0191 0.0472
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0508 0.0766 0.748
Brugia malayi nuclear hormone receptor family member nhr-6 0.0044 0.0034 0.0245
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0103 0.0128 0.0659
Echinococcus granulosus casein kinase ii subunit alpha 0.0143 0.0191 0.0188
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0019 0.0046
Leishmania major DNA polymerase kappa, putative 0.0035 0.002 0.0052
Entamoeba histolytica recQ family helicase, putative 0.0076 0.0085 0.0208
Brugia malayi Cytochrome P450 family protein 0.0031 0.0015 0.0105
Loa Loa (eye worm) hypothetical protein 0.0105 0.0131 0.0834
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0172 0.0237 0.1508
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0204 0.0287 0.0783
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0597 0.0906 0.6463
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0144 0.0391
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0114 0.0326
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0076 0.0085 0.0815
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0083 0.0097 0.0499
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0019 0.0046
Onchocerca volvulus 0.0039 0.0027 0.0169
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0123 0.0159 0.026
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0066 0.0187
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0103 0.0128 0.0365
Brugia malayi exodeoxyribonuclease III family protein 0.0103 0.0128 0.0912
Brugia malayi nuclear hormone receptor family member odr-7 0.0044 0.0034 0.0245
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0133 0.0174 0.1993
Brugia malayi Bromodomain containing protein 0.0334 0.0492 0.3511
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.02 0.0281 0.0765
Schistosoma mansoni thyroid hormone receptor 0.0093 0.0111 0.0181
Brugia malayi nuclear receptor RXR 0.0049 0.0043 0.0304
Brugia malayi 6-phosphofructokinase 0.0113 0.0144 0.1029
Plasmodium vivax multidomain scavenger receptor, putative 0.0044 0.0035 0.1056
Loa Loa (eye worm) hypothetical protein 0.0044 0.0035 0.0222
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0662 0.1009 0.2517
Brugia malayi hypothetical protein 0.0118 0.0152 0.1082
Onchocerca volvulus Bile acid receptor homolog 0.0093 0.0111 0.0696
Loa Loa (eye worm) hypothetical protein 0.0059 0.0058 0.0372
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0144 0.0744
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Echinococcus granulosus cpg binding protein 0.011 0.0139 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0268 0.0669
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0064 0.2068
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0083 0.0097 0.069
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0575 0.0872 0.6221
Brugia malayi Doublecortin family protein 0.0044 0.0035 0.0249
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0379 0.0563 0.1402
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Schistosoma mansoni hypothetical protein 0.0088 0.0105 0.017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.0159 0.1131
Schistosoma mansoni hypothetical protein 0.0054 0.005 0.0079
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0025 0.0006 0.0003
Chlamydia trachomatis endonuclease IV 0.0083 0.0097 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0785 0.1202 0.8574
Schistosoma mansoni coup transcription factor 0.0093 0.0111 0.0181
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0033 0.0018 0.013
Trichomonas vaginalis set domain proteins, putative 0.1037 0.16 0.3995
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0025 0.0006 0.0003
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0003 0.0015
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0051 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0554 0.0838 0.2093
Leishmania major phosphatidylinositol 3-kinase, putative 0.0205 0.0289 0.0788
Plasmodium falciparum JmjC domain-containing protein, putative 0.0141 0.0187 0.6448
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0054 0.0051 0.0081
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.0026 0.0161
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0292 0.0426 0.2714
Loa Loa (eye worm) hypothetical protein 0.0312 0.0457 0.2913
Schistosoma mansoni protein kinase 0.0143 0.0191 0.0313
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0281 0.0701
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0578 0.0876 0.2398
Brugia malayi beta-lactamase family protein 0.0039 0.0027 0.0193
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0066 0.0164
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0053 0.0049 0.0549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0327 0.0481 0.1202
Brugia malayi F/Y-rich N-terminus family protein 0.0063 0.0064 0.0459
Loa Loa (eye worm) PHD-finger family protein 0.0088 0.0105 0.0666
Trichomonas vaginalis PIKK family atypical protein kinase 0.0374 0.0556 0.1387
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0093 0.0111 0.0109
Schistosoma mansoni jumonji/arid domain-containing protein 0.0541 0.0818 0.1359
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Loa Loa (eye worm) ICD-1 protein 0.0077 0.0086 0.055
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0026 0.0069
Brugia malayi hypothetical protein 0.0105 0.0131 0.0933
Trypanosoma brucei protein kinase, putative 0.0053 0.0049 0.0466
Plasmodium falciparum DNA repair protein REV1, putative 0.0035 0.002 0.0654
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0118 0.0152 0.0149
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0027 0.0173
Plasmodium vivax SET domain protein, putative 0.0133 0.0174 0.5963
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0096 0.0214
Echinococcus multilocularis regulator of G protein signaling 7 0.003 0.0013 0.001
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0093 0.0112 0.011
Brugia malayi polk-prov protein 0.0122 0.0158 0.1129
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0144 0.0918
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0457 0.1142
Schistosoma mansoni hypothetical protein 0.1372 0.2128 0.3542
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0027 0.0074
Loa Loa (eye worm) hypothetical protein 0.0062 0.0064 0.0405
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0508 0.0766 0.0764
Trichomonas vaginalis PIKK family atypical protein kinase 0.0578 0.0876 0.2187
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0119 0.0154 0.0979
Onchocerca volvulus 0.0093 0.0111 0.0696
Brugia malayi Bromodomain containing protein 0.0172 0.0236 0.1685
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0044 0.0034 0.0219
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0204 0.0287 0.0717
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0096 0.0494
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0204 0.0287 0.0285
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0426 0.1064
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0029 0.0011 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0191 0.0476
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0033 0.0018 0.0016
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0249 0.0358 0.0862
Brugia malayi orphan nuclear receptor NR2E1 0.0044 0.0034 0.0245
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0204 0.0287 0.2048
Plasmodium falciparum casein kinase II beta chain 0.0038 0.0026 0.0836
Schistosoma mansoni sex comb on midleg homolog 0.0054 0.0051 0.0081
Echinococcus multilocularis polycomb protein SCMH1 0.0054 0.0051 0.0048
Entamoeba histolytica hypothetical protein 0.0118 0.0152 0.0375
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0014 0.0034
Mycobacterium tuberculosis Conserved protein 0.0039 0.0027 0.014
Schistosoma mansoni microtubule-associated protein tau 0.3832 0.6003 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Brugia malayi M-phase phosphoprotein, mpp8 0.0105 0.0131 0.0932
Trichomonas vaginalis PIKK family atypical protein kinase 0.035 0.0518 0.1293
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0123 0.0159 0.5458
Echinococcus multilocularis survival motor neuron protein 1 0.0491 0.074 0.0737
Entamoeba histolytica hypothetical protein 0.0118 0.0152 0.0375
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0093 0.0111 0.0109
Brugia malayi regulator of G-protein signaling egl-10 0.003 0.0013 0.0092
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0044 0.0034 0.0053
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0335 0.0494 0.3084
Brugia malayi PAS domain containing protein 0.0051 0.0045 0.0324
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0332 0.0488 0.1219
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0332 0.0488 0.3483
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0144 0.0142
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0465 0.0698 0.1713
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0103 0.0128 0.0814
Giardia lamblia Sgs1 DNA helicase, putative 0.0073 0.0081 0.0168
Loa Loa (eye worm) hypothetical protein 0.0141 0.0187 0.1191
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0281 0.0808
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0093 0.0111 0.0696
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0093 0.0111 0.0795
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0064 0.0066 0.0186
Schistosoma mansoni jumonji domain containing protein 0.0614 0.0933 0.155
Echinococcus granulosus histone acetyltransferase MYST2 0.0062 0.0063 0.006
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0205 0.0289 0.1842
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0053 0.0133
Trypanosoma cruzi transcription factor btf3, putative 0.0077 0.0086 0.0245
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0508 0.0766 0.2096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0123 0.0159 0.0396
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0033 0.0018 0.0026
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0053 0.0049 0.0314
Loa Loa (eye worm) mbt repeat family protein 0.0054 0.0051 0.0325
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0064 0.0066 0.0164
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0018
Treponema pallidum fructose-bisphosphate aldolase 0.2563 0.4004 1
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.1252 0.1939 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0018 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0144 0.0193 0.0317
Schistosoma mansoni alpha glucosidase 0.0038 0.0026 0.0039
Brugia malayi jmjC domain containing protein 0.0541 0.0818 0.5834
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0137 0.0181 0.129
Echinococcus granulosus JmjC domain containing protein 4 0.0141 0.0187 0.0185
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Brugia malayi PHD-finger family protein 0.0062 0.0064 0.0454
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0209 0.0295 0.0487
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0071
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0027 0.0041
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0138 0.0183 0.0524
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0064 0.0066 0.0063
Loa Loa (eye worm) doublecortin family protein 0.0044 0.0035 0.0222
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0003 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0388 0.0577 0.1441
Brugia malayi follicle stimulating hormone receptor 0.0249 0.0358 0.2554
Schistosoma mansoni blooms syndrome DNA helicase 0.0049 0.0042 0.0066
Trichomonas vaginalis inositol monophosphatase, putative 0.0164 0.0224 0.056
Brugia malayi Serotonin receptor 0.0489 0.0736 0.5252
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.0026 0.007
Toxoplasma gondii FATC domain-containing protein 0.0327 0.0481 0.5536
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0058 0.0146
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0269 0.0389 0.0387
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0147 0.0197 0.1017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0019 0.0046
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0205 0.0289 0.0478
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0018 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0034 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0124 0.0309
Echinococcus multilocularis jumonji domain containing protein 0.0087 0.0102 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0122 0.1176
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0014 0.0034
Onchocerca volvulus 0.0038 0.0025 0.0154
Echinococcus granulosus cysteine protease atg4b 0.0059 0.0058 0.0056
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0134 0.0177 0.0912
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2563 0.4004 1
Plasmodium vivax glycogen synthase kinase 3, putative 0.0053 0.0049 0.1564
Onchocerca volvulus Protein ultraspiracle homolog 0.0093 0.0111 0.0696
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0204 0.0287 0.0713
Echinococcus granulosus intermediate filament protein 0.006 0.006 0.0058
Echinococcus multilocularis casein kinase ii subunit alpha 0.0143 0.0191 0.0188
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0123 0.0159 0.026
Brugia malayi nuclear hormone receptor 0.0093 0.0111 0.0795
Trichomonas vaginalis PIKK family atypical protein kinase 0.0323 0.0475 0.1186
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0204 0.0287 0.0685
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.6369 1 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0205 0.0289 1
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0027 0.0068
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0073 0.0081 0.0913
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0026 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0142 0.0189 0.0471
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0073 0.0081 0.0078
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0123 0.0159 0.181
Trichomonas vaginalis conserved hypothetical protein 0.0204 0.0287 0.0717
Treponema pallidum ATP-dependent DNA helicase 0.0037 0.0024 0.0035
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0144 0.0236
Schistosoma mansoni hypothetical protein 0.0118 0.0152 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0554 0.0838 0.2093
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0059 0.0058 0.0164
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Schistosoma mansoni methyl-cpg binding protein mbd 0.0073 0.008 0.013
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0027 0.0025
Toxoplasma gondii hypothetical protein 0.0028 0.001 0.01
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.1252 0.1939 1
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0335 0.0494 0.3143
Schistosoma mansoni zinc finger protein 0.0044 0.0034 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0105 0.0131 0.0328
Trypanosoma cruzi ISWI complex protein 0.0065 0.0069 0.0194
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0195 0.0272 0.027
Loa Loa (eye worm) hypothetical protein 0.017 0.0234 0.1489
Loa Loa (eye worm) phosphatidylinositol kinase 0.0123 0.0159 0.101
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0123 0.0159 0.1536
Echinococcus granulosus thyroid hormone receptor alpha 0.0044 0.0034 0.0032
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0027 0.0068
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0123 0.0159 0.0156
Trypanosoma brucei DNA polymerase kappa, putative 0.0122 0.0158 0.1533
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0268 0.0669
Trichomonas vaginalis PIKK family atypical protein kinase 0.019 0.0264 0.066
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0003 0.0003
Schistosoma mansoni phd/f-box containing protein 0.0141 0.0187 0.0307
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0332 0.0488 0.1409
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0093 0.0111 0.0795
Trichomonas vaginalis PIKK family atypical protein kinase 0.035 0.0518 0.1293
Echinococcus granulosus Nuclear hormone receptor HR96 0.0044 0.0034 0.0032
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0093 0.0111 0.0109
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0014 0.0034
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0064 0.0715
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0051 0.0262
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0093 0.0111 0.0181
Schistosoma mansoni polycystin 1-related 0.0044 0.0035 0.0054
Brugia malayi Bromodomain containing protein 0.008 0.0092 0.0657
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0332 0.0488 0.4763
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0204 0.0287 0.0826
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0137 0.0181 0.0178
Plasmodium vivax DNA repair protein REV1, putative 0.0035 0.002 0.0551
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0049 0.0123
Mycobacterium tuberculosis Conserved hypothetical protein 0.0123 0.0159 0.0818
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0003 0.0015
Brugia malayi hypothetical protein 0.0044 0.0035 0.0249
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0043 0.0034 0.0093
Mycobacterium ulcerans hypothetical protein 0.0035 0.002 0.0106
Trichomonas vaginalis DNA helicase recq1, putative 0.0086 0.0101 0.0253
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0205 0.0289 0.0287
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0292 0.0426 0.304
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0026 0.0066
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0204 0.0287 0.2793
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0014 0.0034
Giardia lamblia Kinase, PLK 0.02 0.0281 0.0669
Schistosoma mansoni protein phosphatase 2C 0.0141 0.0187 0.0307
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0105 0.0131 0.1497
Schistosoma mansoni regulator of G protein signaling 0.003 0.0013 0.0017
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0016 0.0103
Entamoeba histolytica protein kinase, putative 0.0053 0.0049 0.0119
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0044 0.0034 0.0032
Brugia malayi FAT domain containing protein 0.0222 0.0316 0.2254
Loa Loa (eye worm) hypothetical protein 0.0093 0.0111 0.071
Loa Loa (eye worm) MBCTL1 0.0062 0.0063 0.04
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0026 0.0064
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.001 0.0024
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0027 0.014
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0093 0.0111 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.019 0.0264 0.066
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0426 0.1064
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0064 0.0715
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0076 0.0085 0.0229
Giardia lamblia GTOR 0.0597 0.0906 0.2236
Trypanosoma brucei Casein kinase II 0.0143 0.0191 0.1849
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.006
Onchocerca volvulus 0.0024 0.0003 0.0018
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0003 0.0015
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0312 0.0457 0.132
Brugia malayi intracellular kinase 0.0053 0.0049 0.0352
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0334 0.0491 0.0814
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Trypanosoma brucei polo-like protein kinase 0.02 0.0281 0.273
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Echinococcus granulosus high voltage activated calcium channel beta 0.009 0.0108 0.0106
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0011 0.0009
Echinococcus multilocularis casein kinase ii subunit beta 0.0038 0.0026 0.0023
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0144 0.0356
Leishmania major hypothetical protein, conserved 0.0065 0.0069 0.0184
Brugia malayi hypothetical protein 0.0044 0.0034 0.0245
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0026 0.006
Schistosoma mansoni peptidase Clp (S14 family) 0.0083 0.0096 0.0155
Loa Loa (eye worm) DR-78 0.0044 0.0034 0.0219
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0062 0.0064 0.0102
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0027 0.014
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0024 0.026
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0399 0.0595 0.1481
Echinococcus granulosus lysosomal alpha glucosidase 0.0172 0.0237 0.0234
Echinococcus multilocularis cysteine protease atg4b 0.0059 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0082
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0044 0.0034 0.0215
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0064 0.0066 0.0063
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0094 0.0114 0.0326
Loa Loa (eye worm) hypothetical protein 0.0093 0.0111 0.071
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0003 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0573 0.0868 0.2168
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1145 0.1769 0.1767
Brugia malayi mbt repeat family protein 0.0054 0.0051 0.0363
Entamoeba histolytica peptidase, C54 family 0.0059 0.0058 0.0141
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0037 0.0024 0.0065
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0073 0.0081 0.0515
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0364 0.0539 0.5263
Loa Loa (eye worm) hypothetical protein 0.0049 0.0043 0.0271
Echinococcus granulosus ecdysone induced protein 78C 0.0093 0.0111 0.0109
Echinococcus multilocularis geminin 0.0353 0.0522 0.052
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0028 0.001 0.0007
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0123 0.0159 0.5408
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0126 0.0164 0.0161
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0093 0.0111 0.0109
Echinococcus multilocularis transcription factor Dp 1 0.0294 0.0429 0.0426
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0268 0.0669
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0105 0.0131 0.4452
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0186 0.0259 0.1652
Onchocerca volvulus 0.0044 0.0034 0.0215
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0204 0.0287 0.0474
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0093 0.0111 0.0795
Trypanosoma cruzi DNA polymerase kappa, putative 0.02 0.028 0.0807
Brugia malayi Inositol-1 0.0164 0.0224 0.16
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0059 0.0058 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0597 0.0906 0.2263
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0093 0.0111 0.071
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0222 0.0316 0.0314
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0025 0.0022
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.002 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.002 0.0054
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0033 0.0018 0.0016
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.001 0.0053
Entamoeba histolytica protein kinase rad3, putative 0.0312 0.0457 0.1138
Mycobacterium ulcerans hypothetical protein 0.0024 0.0003 0.0015
Onchocerca volvulus 0.0039 0.0027 0.0169
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0059 0.0058 0.0554
Brugia malayi Protein kinase domain containing protein 0.0335 0.0494 0.3521
Echinococcus granulosus ubiquitin specific protease 41 0.0204 0.0287 0.0285
Brugia malayi 6-phosphofructokinase 0.0113 0.0144 0.1029
Echinococcus multilocularis microtubule associated protein 2 0.3832 0.6003 0.6002
Trypanosoma brucei DNA polymerase IV, putative 0.0178 0.0246 0.2394
Echinococcus multilocularis Peptidase C54 0.0059 0.0058 0.0056
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0144 0.0413
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0591 0.0897 0.2239
Brugia malayi jmjC domain containing protein 0.0656 0.0999 0.7125
Entamoeba histolytica transcription factor BTF3, putative 0.0077 0.0086 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0086 0.0215
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0587 0.0891 0.148
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0003 0.0003
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0147 0.0197 0.1017
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0597 0.0906 0.8852
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0123 0.0159 0.0396
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0024 0.0003 0.0016
Loa Loa (eye worm) hypothetical protein 0.0259 0.0374 0.2381
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0093 0.0111 0.0795
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0205 0.0289 0.2063
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0318 0.0466 0.4546
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0535 0.0808 0.7891
Brugia malayi Nuclear hormone receptor-like 1 0.0093 0.0111 0.0795
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0123 0.0159 0.5408
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0164 0.0224 1
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.028 0.2729
Brugia malayi conserved hypotetical protein 0.0044 0.0034 0.0245
Loa Loa (eye worm) hypothetical protein 0.0083 0.0097 0.0616
Onchocerca volvulus 0.0039 0.0027 0.0169
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0281 0.0701
Brugia malayi Glycosyl hydrolases family 31 protein 0.0172 0.0237 0.1688
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0093 0.0111 0.0109
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0123 0.0159 0.181
Schistosoma mansoni autophagin-1 (C54 family) 0.0059 0.0058 0.0093
Loa Loa (eye worm) hypothetical protein 0.0123 0.0159 0.101
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0785 0.1202 0.3477
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0345 0.0509 0.5856
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0546 0.0826 0.8064
Loa Loa (eye worm) hypothetical protein 0.0049 0.0043 0.0271
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0578 0.0876 0.8557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0559 0.0846 0.2112
Toxoplasma gondii hypothetical protein 0.0056 0.0053 0.0598
Trypanosoma cruzi transcription factor btf3, putative 0.0077 0.0086 0.0245
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.02 0.028 0.07
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0323 0.0475 0.1182
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0204 0.0287 0.0285
Entamoeba histolytica protein kinase domain containing protein 0.0143 0.0191 0.0472
Schistosoma mansoni RAR-like nuclear receptor 0.0093 0.0111 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0222 0.0316 0.0789
Brugia malayi Nuclear hormone receptor E75 0.0044 0.0034 0.0245
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0334 0.0491 0.0489
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0064 0.0066 0.0164
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0206 0.0289 0.0287
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0205 0.0289 0.2814
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0123 0.0159 0.0454
Plasmodium vivax unspecified product 0.0143 0.0191 0.6535
Onchocerca volvulus 0.1038 0.16 1
Schistosoma mansoni hypothetical protein 0.01 0.0123 0.0201
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0014 0.0315
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Mycobacterium leprae Probable lipase LipE 0.0039 0.0027 0.014
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.002 0.0184
Schistosoma mansoni DNA polymerase eta 0.0141 0.0188 0.031
Echinococcus granulosus lysine specific demethylase 6a 0.0141 0.0187 0.0185
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0027 0.014
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0026 0.0064
Entamoeba histolytica acetyltransferase, GNAT family 0.0087 0.0103 0.0253
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0141 0.0187 0.0307
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.002 0.0184
Loa Loa (eye worm) CHromoDomain protein family member 0.0025 0.0006 0.0036
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0066 0.0164
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0057 0.0055 0.0611
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0249 0.0358 0.2281
Loa Loa (eye worm) phosphatidylinositol 3 0.0597 0.0906 0.5771
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0083 0.0096 0.3195
Echinococcus multilocularis expressed conserved protein 0.0085 0.01 0.0097
Schistosoma mansoni steroid hormone receptor ad4bp 0.0093 0.0111 0.0181
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0083 0.0097 0.0499
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0026 0.0064
Loa Loa (eye worm) jmjC domain-containing protein 0.0141 0.0187 0.1191
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0093 0.0111 0.0795
Trichomonas vaginalis PIKK family atypical protein kinase 0.0123 0.0159 0.0396
Mycobacterium ulcerans hypothetical protein 0.0039 0.0027 0.014
Loa Loa (eye worm) glutaminase 2 0.087 0.1336 0.8506
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0237 0.0234
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0027 0.0068
Echinococcus granulosus polycomb protein SCMH1 0.0054 0.0051 0.0048
Toxoplasma gondii ck2 beta subunit 0.0038 0.0026 0.0277
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0112 0.0143 0.0909
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0573 0.0868 0.2168
Brugia malayi PHD-finger family protein 0.0034 0.0019 0.0136
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0144 0.036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2563 0.4004 1
Echinococcus multilocularis Protein lozenge 0.0063 0.0065 0.0062
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0026 0.0023
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0508 0.0766 0.1272
Loa Loa (eye worm) hypothetical protein 0.0032 0.0015 0.0099
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0508 0.0766 0.2213
Schistosoma mansoni retinoic acid receptor RXR 0.0093 0.0111 0.0181
Leishmania major DNA polymerase eta, putative 0.0141 0.0188 0.0512
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0064 0.0066 0.0164
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.0026 0.006
Loa Loa (eye worm) hypothetical protein 0.0141 0.0188 0.1199
Schistosoma mansoni hypothetical protein 0.0085 0.01 0.0162
Loa Loa (eye worm) beta-lactamase 0.0039 0.0027 0.0173
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0083 0.0096 0.0093
Plasmodium falciparum glycogen synthase kinase 3 0.0053 0.0049 0.1656
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0038 0.0026 0.0277
Giardia lamblia Fructose-bisphosphate aldolase 0.2563 0.4004 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0096 0.0494
Loa Loa (eye worm) hypothetical protein 0.0205 0.0288 0.1836
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0154 0.0209 0.0206
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0281 0.0701
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0268 0.0669
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0019 0.0046
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.009 0.0108 0.0105
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0026 0.0007 0.0178
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0024 0.0003 0.0018
Onchocerca volvulus 0.01 0.0122 0.0765
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0093 0.0111 0.071
Loa Loa (eye worm) jmjC domain-containing protein 0.0129 0.0168 0.1071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0093 0.0111 0.071
Onchocerca volvulus 0.0123 0.0159 0.0991
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0027 0.014
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.006 0.006 0.0383
Onchocerca volvulus 0.0105 0.0131 0.0817
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0327 0.0481 0.1389
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0103 0.0128 0.0659
Schistosoma mansoni lipoxygenase 0.0195 0.0272 0.0449
Echinococcus granulosus bloom syndrome protein 0.0086 0.0101 0.0099
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0587 0.0891 0.6352
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0332 0.0488 0.1219
Echinococcus multilocularis bloom syndrome protein 0.0086 0.0101 0.0099
Brugia malayi SH2 domain containing protein 0.0355 0.0524 0.374
Onchocerca volvulus 0.0123 0.0159 0.0991
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Brugia malayi hypothetical protein 0.0504 0.0759 0.5413
Trypanosoma brucei unspecified product 0.0078 0.0088 0.0842
Leishmania major mitochondrial DNA polymerase beta 0.0671 0.1023 0.2802
Loa Loa (eye worm) hypothetical protein 0.0227 0.0324 0.2061
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0049 0.0043 0.004
Brugia malayi nuclear hormone receptor 0.0044 0.0034 0.0245
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0028 0.001 0.007
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0191 0.0476
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0018 0.0016
Echinococcus granulosus microtubule associated protein 2 0.3832 0.6003 0.6002
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0086 0.0215
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.02 0.0281 0.0278
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0144 0.036
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0062 0.0063 0.0448
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0019 0.0046
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0237 0.0234
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0656 0.0999 0.0997
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.0026 0.007
Schistosoma mansoni rab6-interacting 0.0044 0.0035 0.0054
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0235 0.0335 0.0333
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.002 0.0017
Echinococcus multilocularis lamin dm0 0.006 0.006 0.0058
Trichomonas vaginalis glutaminase, putative 0.087 0.1336 0.3335
Echinococcus multilocularis JmjC domain containing protein 4 0.0141 0.0187 0.0185
Giardia lamblia Kinase, CMGC GSK 0.0053 0.0049 0.0089
Brugia malayi hypothetical protein 0.0491 0.074 0.5277
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0658 0.1003 0.2501
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0134 0.0177 0.048
Treponema pallidum exodeoxyribonuclease (exoA) 0.0103 0.0128 0.0294
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1145 0.1769 0.2944
Echinococcus multilocularis muscleblind protein 1 0.032 0.047 0.0467
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0656 0.0999 0.0997
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0144 0.036
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0173
Loa Loa (eye worm) hypothetical protein 0.0105 0.0131 0.0832
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0141 0.0187 0.2139
Echinococcus multilocularis lysine specific demethylase 5A 0.0527 0.0796 0.0794
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0093 0.0111 0.071
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0033 0.0018 0.0016
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0003 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0093 0.0111 0.0181
Schistosoma mansoni bromodomain containing protein 0.0032 0.0015 0.0022
Echinococcus granulosus survival motor neuron protein 1 0.0491 0.074 0.0737
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0043 0.0304
Echinococcus granulosus dnaJ subfamily B 0.1372 0.2128 0.2126
Loa Loa (eye worm) hypothetical protein 0.0122 0.0158 0.1008
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0332 0.0488 0.1216
Echinococcus granulosus lamin 0.006 0.006 0.0058
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0327 0.0481 0.3434
Mycobacterium leprae conserved hypothetical protein 0.0123 0.0159 0.0818
Brugia malayi beta-lactamase 0.0039 0.0027 0.0193
Loa Loa (eye worm) hypothetical protein 0.0504 0.0759 0.4834
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0035 0.0032
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0312 0.0457 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0093 0.0111 0.0795
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0587 0.0891 0.0888
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0003 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.002 0.0184
Brugia malayi glutaminase DH11.1 0.087 0.1336 0.9526
Loa Loa (eye worm) hypothetical protein 0.0049 0.0043 0.0271
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0318 0.0466 0.1345
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0026 0.0277
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0064 0.0066 0.0186
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0027 0.014
Brugia malayi jmjC domain containing protein 0.0141 0.0187 0.1334
Brugia malayi phosphofructokinase 0.0113 0.0144 0.1029
Schistosoma mansoni casein kinase II beta subunit 0.0038 0.0026 0.0039
Schistosoma mansoni kinase 0.0103 0.0128 0.0209
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0045 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0049 0.0123
Brugia malayi mbt repeat family protein 0.0054 0.0051 0.0363
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0205 0.0289 0.0718
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.0159 0.101
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0096 0.3269
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0123 0.0159 0.181
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0003 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0578 0.0876 0.2187
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0053 0.0049 0.0131
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0093 0.0111 0.0181
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0027 0.014
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0093 0.0112 0.0182
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0164 0.0224 0.056
Loa Loa (eye worm) hypoxia-induced factor 1 0.0157 0.0213 0.1357
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0087 0.0084
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0426 0.1064
Loa Loa (eye worm) hypothetical protein 0.0206 0.0289 0.1843
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0327 0.0481 0.4695
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0222 0.0316 0.0314
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0014 0.003
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0034 0.0053
Brugia malayi Muscleblind-like protein 0.032 0.047 0.3351
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Brugia malayi Pre-SET motif family protein 0.0133 0.0174 0.1244
Onchocerca volvulus 0.0504 0.0759 0.4743
Echinococcus multilocularis lysine specific demethylase 6a 0.0141 0.0187 0.0185
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0164 0.0224 0.2178
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0173
Schistosoma mansoni terminal deoxycytidyl transferase 0.0112 0.0143 0.0233
Echinococcus granulosus jumonji domain containing 1A 0.0141 0.0187 0.0185
Loa Loa (eye worm) hypothetical protein 0.0355 0.0524 0.3339
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0093 0.0111 0.0109
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0912 0.1402 0.8929
Echinococcus granulosus serine protein kinase ATM 0.0327 0.0481 0.0479
Schistosoma mansoni DNA polymerase IV / kappa 0.0035 0.002 0.003
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0205 0.0289 0.0788
Loa Loa (eye worm) runx1 0.0063 0.0065 0.0414
Giardia lamblia Phosphatidylinositol 4-kinase 0.0123 0.0159 0.0363
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0122 0.0158 0.1533
Trypanosoma brucei DNA polymerase eta, putative 0.0141 0.0188 0.1827
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Entamoeba histolytica hypothetical protein 0.0123 0.0159 0.0392
Plasmodium falciparum casein kinase II beta chain 0.0038 0.0026 0.0836
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0044 0.0034 0.0053
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0058 0.0146
Giardia lamblia Hypothetical protein 0.0123 0.0159 0.0363
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0035 0.0032
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0053 0.0049 0.0314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0546 0.0826 0.2061
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0076 0.0085 0.0241
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0066 0.0164
Echinococcus granulosus dna polymerase kappa 0.02 0.028 0.0278
Brugia malayi ImpB/MucB/SamB family protein 0.0112 0.0143 0.1018
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0144 0.0335
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0034 0.0032
Echinococcus granulosus Nuclear hormone receptor HR96 0.0044 0.0034 0.0032
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0143 0.0191 0.1214
Loa Loa (eye worm) hypothetical protein 0.0093 0.0111 0.071
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0093 0.0111 0.0795
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.1252 0.1939 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0018 0.0016
Onchocerca volvulus 0.0044 0.0035 0.0218
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0281 0.0701
Loa Loa (eye worm) hypothetical protein 0.0093 0.0111 0.071
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.002 0.0054
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0027 0.0041
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0591 0.0897 0.2239
Brugia malayi nuclear receptor NHR-88 0.0044 0.0034 0.0245
Schistosoma mansoni fkbp-rapamycin associated protein 0.0312 0.0457 0.0758
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0281 0.0701
Schistosoma mansoni nuclear hormone receptor 0.0093 0.0111 0.0181
Onchocerca volvulus Alhambra homolog 0.0062 0.0064 0.0398
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0154 0.0208 0.0205
Toxoplasma gondii hypothetical protein 0.0108 0.0136 0.1551
Entamoeba histolytica recQ family helicase, putative 0.0036 0.0022 0.0051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0093 0.0111 0.0109
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0043 0.0034 0.0084
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.009 0.0108 0.0105
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0123 0.0159 0.0156
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0026 0.0064
Brugia malayi small heat shock protein 0.0637 0.0969 0.6909
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0103 0.0128 0.4325
Schistosoma mansoni alpha-glucosidase 0.0148 0.0199 0.0327
Schistosoma mansoni ap endonuclease 0.0103 0.0128 0.0209
Echinococcus granulosus SAM and MBT domain containing protein 0.0054 0.0051 0.0048
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0268 0.0669
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0083 0.0096 0.0093
Echinococcus granulosus histone acetyltransferase KAT2B 0.0105 0.0131 0.0129
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0053 0.0049 0.0138
Trypanosoma cruzi ISWI complex protein 0.0065 0.0069 0.0194
Loa Loa (eye worm) inositol-1 0.0164 0.0224 0.1428
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0019 0.0046
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0141 0.0187 0.2139
Giardia lamblia DINP protein human, muc B family 0.0134 0.0177 0.0409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0573 0.0868 0.2168
Loa Loa (eye worm) hypothetical protein 0.032 0.047 0.2992
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0205 0.0289 0.1805
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0043 0.0304
Loa Loa (eye worm) histone methyltransferase 0.0035 0.002 0.0128
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0123 0.0159 0.0156
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0846 0.1299 0.1296
Onchocerca volvulus 0.0144 0.0193 0.1206
Echinococcus granulosus Peptidase C54 0.0059 0.0058 0.0056
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0044 0.0034 0.0032
Trypanosoma cruzi DNA polymerase kappa, putative 0.02 0.028 0.0807
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0064 0.0066 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0093 0.0111 0.0795
Schistosoma mansoni voltage-gated cation channel 0.0033 0.0018 0.0026
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0573 0.0868 0.0866
Schistosoma mansoni transcription factor btf3 0.0077 0.0086 0.014
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0164 0.0224 0.0556
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0185 0.0305
Schistosoma mansoni lamin 0.006 0.006 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0426 0.1064
Brugia malayi nuclear receptor NHR-67 0.0044 0.0034 0.0245
Echinococcus granulosus fetal alzheimer antigen falz 0.0102 0.0126 0.0124
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0096 0.1085
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0043 0.0067
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0044 0.0034 0.0032
Mycobacterium ulcerans beta-lactamase 0.0039 0.0027 0.014
Loa Loa (eye worm) CXXC zinc finger family protein 0.0096 0.0117 0.0747
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0018
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0093 0.0111 0.0181
Trichomonas vaginalis esterase, putative 0.0039 0.0027 0.0068
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0222 0.0316 0.2013
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0587 0.0891 0.2574
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0014 0.0139
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0035 0.1153
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0014 0.0315
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0205 0.0289 0.0833
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0083 0.0097 0.3315
Trypanosoma brucei ISWI complex protein 0.0065 0.0069 0.0655
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0026 0.0064
Schistosoma mansoni inositol monophosphatase 0.0164 0.0224 0.0369
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0093 0.0111 0.071
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0062 0.0063 0.006
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0204 0.0287 0.0474
Onchocerca volvulus 0.01 0.0123 0.0772
Trichomonas vaginalis PIKK family atypical protein kinase 0.0554 0.0838 0.2093
Loa Loa (eye worm) intermediate filament protein 0.006 0.006 0.0383
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0027 0.0193
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0785 0.1202 0.3002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0006 0.0005
Echinococcus granulosus muscleblind protein 0.032 0.047 0.0467
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0064 0.0066 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0573 0.0868 0.2168
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.0026 0.0064
Echinococcus multilocularis regulator of G protein signaling 7 0.003 0.0013 0.001
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0058 0.0146
Loa Loa (eye worm) Csnk2b protein 0.0038 0.0026 0.0164
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0173
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0137 0.0181 0.0933
Echinococcus granulosus casein kinase ii subunit beta 0.0038 0.0026 0.0023
Echinococcus multilocularis zinc finger protein 0.0097 0.0119 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0535 0.0808 0.2017
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0327 0.0481 0.0798
Trypanosoma cruzi hypothetical protein, conserved 0.2214 0.3454 1
Schistosoma mansoni ap endonuclease 0.0103 0.0128 0.0209
Entamoeba histolytica hypothetical protein 0.0118 0.0152 0.0375
Trichomonas vaginalis DNA helicase recq, putative 0.0076 0.0085 0.0212
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0191 0.0476
Echinococcus multilocularis inositol monophosphatase 1 0.0164 0.0224 0.0222
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0028 0.001 0.007
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0195 0.0272 0.027
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0066 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0345 0.0509 0.1271
Leishmania major phosphatidylinositol 3-kinase, putative 0.0535 0.0808 0.2211
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.02 0.0281 0.1787
Echinococcus multilocularis Zinc finger, PHD finger 0.0205 0.0289 0.0287
Onchocerca volvulus 0.0044 0.0034 0.0215
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2563 0.4004 1
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.028 0.2729
Echinococcus multilocularis RUN 0.0044 0.0035 0.0032
Loa Loa (eye worm) hypothetical protein 0.0073 0.0081 0.0515
Schistosoma mansoni single-minded 0.0051 0.0045 0.0071
Loa Loa (eye worm) hypothetical protein 0.0345 0.0509 0.3243
Loa Loa (eye worm) jmjC domain-containing protein 0.0141 0.0187 0.1191
Onchocerca volvulus Serine\/threonine kinase homolog 0.02 0.0281 0.1754
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0027 0.014
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0062 0.0063 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0191 0.0476
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0049 0.0043 0.0271
Brugia malayi ecdysteroid receptor 0.0093 0.0111 0.0795
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0093 0.0111 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.02 0.028 0.2729
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2563 0.4004 1
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0123 0.0159 0.0454
Schistosoma mansoni hypothetical protein 0.035 0.0518 0.0858
Trypanosoma brucei DNA polymerase IV, putative 0.02 0.028 0.2729
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0058 0.0146
Loa Loa (eye worm) hypothetical protein 0.0039 0.0027 0.0173
Onchocerca volvulus 0.0044 0.0035 0.0218
Mycobacterium ulcerans hypothetical protein 0.0354 0.0523 0.2696
Leishmania major DNA polymerase kappa, putative 0.0134 0.0177 0.048
Brugia malayi tailless protein 0.0044 0.0034 0.0245
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.0026 0.0735
Echinococcus granulosus Polycystic kidney disease protein 0.0044 0.0035 0.0032
Loa Loa (eye worm) hypothetical protein 0.0141 0.0187 0.1191
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0044 0.0034 0.0032
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.002 0.0184
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0281 0.0808
Echinococcus multilocularis tumor protein p63 0.0353 0.0521 0.0519
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0281 0.0463
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0093 0.0111 0.0181
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0003 0.0015
Plasmodium falciparum casein kinase 2, alpha subunit 0.0143 0.0191 0.6572
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0026 0.0064
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0027 0.0025
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0164 0.0224 0.056
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0205 0.0289 0.0722
Echinococcus granulosus expressed protein 0.0389 0.0579 0.0577
Toxoplasma gondii histone lysine methyltransferase SET1 0.0205 0.0289 0.3317
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0105 0.0131 0.0328
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0027 0.014
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0046 0.0038 0.0422
Leishmania major basic transcription factor 3a, putative 0.0077 0.0086 0.0232
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0597 0.0906 0.2481
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0026 0.0183
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.0219
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0573 0.0868 0.2168
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0205 0.0289 0.0718
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0014 0.0139
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0066 0.0164
Brugia malayi ecdysone receptor 0.0044 0.0034 0.0245
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0597 0.0906 0.2619
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0026 0.0064
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0141 0.0187 0.0537
Loa Loa (eye worm) hypothetical protein 0.0093 0.0111 0.071
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0587 0.0891 0.2574
Loa Loa (eye worm) PHD-finger family protein 0.0062 0.0064 0.0405
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0205 0.0289 0.0722
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0112 0.0143 0.0233
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.0159 0.101
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0073 0.0081 0.0078
Echinococcus granulosus inositol monophosphatase 1 0.0164 0.0224 0.0222
Toxoplasma gondii NAC domain-containing protein 0.0077 0.0086 0.0977
Onchocerca volvulus 0.0052 0.0047 0.0293
Loa Loa (eye worm) hypothetical protein 0.0083 0.0096 0.0609
Giardia lamblia Kinase, CMGC CK2 0.0143 0.0191 0.0443
Echinococcus multilocularis protein kinase shaggy 0.0053 0.0049 0.0047
Giardia lamblia DNA damage repair protein 0.0035 0.002 0.0017
Echinococcus granulosus phd:f box containing protein 0.0141 0.0187 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0559 0.0846 0.2112
Loa Loa (eye worm) hypothetical protein 0.032 0.047 0.2992

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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