Detailed information for compound 911613

Basic information

Technical information
  • TDR Targets ID: 911613
  • Name: 3-acetyl-5-(4-chlorophenyl)-1-phenyl-3a,6a-di hydropyrrolo[3,4-d]pyrazole-4,6-dione
  • MW: 367.786 | Formula: C19H14ClN3O3
  • H donors: 0 H acceptors: 3 LogP: 2.93 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)N1C(=O)C2C(C1=O)C(=NN2c1ccccc1)C(=O)C
  • InChi: 1S/C19H14ClN3O3/c1-11(24)16-15-17(23(21-16)14-5-3-2-4-6-14)19(26)22(18(15)25)13-9-7-12(20)8-10-13/h2-10,15,17H,1H3
  • InChiKey: XCCQWAIPVYBTNL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-acetyl-5-(4-chlorophenyl)-1-phenyl-3a,6a-dihydropyrrolo[3,4-d]pyrazole-4,6-quinone
  • 5-(4-chlorophenyl)-3-ethanoyl-1-phenyl-3a,6a-dihydropyrrolo[3,4-d]pyrazole-4,6-dione
  • ST5433333

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Mycobacterium ulcerans lipase LipD 0.0106 0.0387 0.4384
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Entamoeba histolytica hypothetical protein 0.0019 0.003 0.0723
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0121 0.0447 0.0449
Loa Loa (eye worm) hypothetical protein 0.0038 0.0108 0.0108
Toxoplasma gondii exonuclease III APE 0.0059 0.0192 0.143
Schistosoma mansoni loxhd1 0.0041 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0031
Trichomonas vaginalis inositol monophosphatase, putative 0.0112 0.0411 0.4072
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Brugia malayi G protein-coupled receptor F59B2.13 0.0075 0.0259 0.026
Onchocerca volvulus 0.0075 0.0259 0.0317
Schistosoma mansoni tyrosine kinase 0.0019 0.003 0.0031
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0119 0.0119
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0121 0.0447 0.0449
Echinococcus granulosus death domain containing protein 0.0015 0.0014 0.0014
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0269 0.0271
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Brugia malayi Abnormal catecholamine distribution protein 1 0.244 0.9947 1
Schistosoma mansoni hypothetical protein 0.0075 0.0259 0.026
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0063 0.0208 0.0209
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0027 0.0037
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.034 0.1345 0.1352
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0012 0.0003 0.0003
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0075 0.0259 0.0317
Schistosoma mansoni glutamate receptor AMPA 0.0157 0.0594 0.0597
Brugia malayi latrophilin 2 splice variant baaae 0.021 0.0814 0.0818
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0115 0.0422
Echinococcus granulosus Ankyrin 0.0015 0.0014 0.0014
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.034 0.1345 0.1352
Echinococcus granulosus orexin receptor type 2 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0387 0.3836
Brugia malayi beta-lactamase 0.0106 0.0387 0.0389
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0119 0.0119
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.006 0.0449
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Echinococcus granulosus glutamate receptor NMDA 0.008 0.028 0.0282
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0058 0.0189 0.2142
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0115 0.1307
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0001 0.0001
Brugia malayi TAR-binding protein 0.0067 0.0225 0.0226
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0236 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0001
Onchocerca volvulus 0.034 0.1345 0.1649
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1831 0.745 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0075 0.0259 0.026
Echinococcus granulosus glycine receptor subunit beta 0.0121 0.0447 0.0449
Brugia malayi G-protein coupled receptor 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0007
Schistosoma mansoni neuropeptide receptor 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.0351 0.0353
Echinococcus granulosus GPCR family 2 0.0097 0.0351 0.0353
Echinococcus granulosus allatostatin A receptor 0.0075 0.0259 0.026
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0012 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.0075 0.0259 0.026
Brugia malayi Sodium:neurotransmitter symporter family protein 0.2004 0.8158 0.8202
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0014 0.0014
Mycobacterium leprae putative cytochrome p450 0.004 0.0115 0.2748
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0121 0.0447 0.0449
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Brugia malayi beta-lactamase family protein 0.0106 0.0387 0.0389
Echinococcus multilocularis inositol monophosphatase 1 0.0112 0.0411 0.0411
Brugia malayi Dopamine receptor 0.0075 0.0259 0.026
Brugia malayi excitatory GABA receptor EXP-1A 0.0121 0.0447 0.0449
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0121 0.0447 0.0449
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0121 0.0447 0.0449
Schistosoma mansoni sodium-dependent amino acid transporter 0.034 0.1345 0.1352
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.055 0.055
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0042 0.0419
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0007 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0012 0 0.0001
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0019 0.0019
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0236 0.0317
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.2004 0.8158 0.8202
Onchocerca volvulus 0.0014 0.0007 0.0009
Leishmania major extracellular receptor, putative 0.0019 0.003 0.0041
Echinococcus granulosus glycine receptor subunit beta 0.0121 0.0447 0.0449
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Loa Loa (eye worm) hypothetical protein 0.0939 0.3798 0.3818
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0121 0.0447 0.0449
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0075 0.0259 0.0259
Brugia malayi Cytochrome P450 family protein 0.004 0.0115 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0259 0.026
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0115 0.0422
Brugia malayi Receptor family ligand binding region containing protein 0.0019 0.003 0.0031
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0027 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0646 0.6397
Onchocerca volvulus 0.0106 0.0387 0.0475
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0078 0.0583
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0078 0.058
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0019 0.003 0.0031
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.034 0.1345 1
Leishmania major C-14 sterol reductase, putative 0.009 0.032 0.0429
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0019 0.0019
Brugia malayi Dopamine receptor protein 2 0.0075 0.0259 0.026
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0115 0.1307
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0151 0.0185
Echinococcus granulosus sex peptide receptor 0.0075 0.0259 0.026
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0115 0.1307
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0259 0.0259
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0031
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0 0.0001
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0115 0.1307
Loa Loa (eye worm) hypothetical protein 0.0041 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0041 0.0119 0.0119
Trypanosoma cruzi C-14 sterol reductase, putative 0.009 0.032 0.0429
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0269 0.0269
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0078 0.058
Echinococcus multilocularis sodium and chloride dependent glycine 0.034 0.1345 0.1345
Mycobacterium ulcerans beta-lactamase 0.0106 0.0387 0.4384
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0012 0 0.0001
Schistosoma mansoni hypothetical protein 0.0307 0.1211 0.1217
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0121 0.0447 0.0447
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0065 0.0218 0.022
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0447 0.0449
Onchocerca volvulus 0.0075 0.0259 0.0317
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.01 0.0363 0.1328
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0019 0.0019
Chlamydia trachomatis glutamine binding protein 0.0018 0.0028 0.0205
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0042 0.0043
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.042 0.0422
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.093 0.0935
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0192 0.0258
Onchocerca volvulus 0.0082 0.0288 0.0353
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0012 0.0003 0.0028
Brugia malayi neuropeptide F receptor 0.0075 0.0259 0.026
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0063 0.0208 0.0208
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0012 0.0003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0031
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0075 0.0259 0.026
Brugia malayi hypothetical protein 0.0056 0.018 0.0181
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0151 0.0152
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0014 0.0014
Brugia malayi G protein-coupled receptor 0.0075 0.0259 0.026
Schistosoma mansoni neuropeptide receptor 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0012 0 0.0004
Brugia malayi MH2 domain containing protein 0.0121 0.0447 0.0449
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.0003
Echinococcus multilocularis 0.004 0.0115 0.0115
Echinococcus granulosus neuropeptide receptor 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0106 0.0387 0.0389
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0075 0.0259 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0176 0.0672 0.0676
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0027 0.0037
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0112 0.0411 0.3057
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0227 0.0883 0.3231
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0192 0.0258
Echinococcus granulosus tm gpcr rhodopsin 0.1145 0.4643 0.4668
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Loa Loa (eye worm) glutamate receptor 0.0019 0.003 0.0031
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0065 0.0218 0.022
Loa Loa (eye worm) RecQ helicase 0.0022 0.0042 0.0043
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0019 0.003 0.003
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0115 0.1307
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0236 0.0236
Schistosoma mansoni hypothetical protein 0.1221 0.4955 0.4981
Trypanosoma brucei cytochrome P450, putative 0.0058 0.0189 0.0254
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0259 0.0259
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.001
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.0003
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0225 0.0225
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0027 0.0027
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.2004 0.8158 0.8202
Schistosoma mansoni hypothetical protein 0.0075 0.0259 0.026
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0027 0.0027
Brugia malayi AKH receptor 0.0075 0.0259 0.026
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0192 0.0193
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0146 0.055 0.0553
Onchocerca volvulus 0.0012 0 0.0001
Echinococcus granulosus tyrosine kinase 0.0019 0.003 0.0031
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0019 0.003 0.003
Brugia malayi putative neuropeptide receptor NPR1 0.0075 0.0259 0.026
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.034 0.1345 0.1352
Loa Loa (eye worm) acetyltransferase 0.0141 0.053 0.0532
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.0387 0.0389
Trichomonas vaginalis esterase, putative 0.0106 0.0387 0.3836
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0056 0.0413
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0178 0.0178
Onchocerca volvulus 0.2004 0.8158 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0259 0.026
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0007 0.0072
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Schistosoma mansoni lipoxygenase 0.018 0.0689 0.0693
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0387 0.052
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0121 0.0447 0.0447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0047 0.0143 0.0144
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0019 0.0025
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0075 0.0259 0.026
Onchocerca volvulus 0.0075 0.0259 0.0317
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0 0.0001
Brugia malayi Melatonin receptor type 1A 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.034 0.1345 0.1352
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0122 0.0905
Onchocerca volvulus 0.034 0.1345 0.1649
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0115 0.1307
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0411 0.0552
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.006 0.0446
Onchocerca volvulus 0.0106 0.0387 0.0475
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0121 0.0447 0.0447
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0121 0.0447 0.0449
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0189 0.019
Echinococcus granulosus glycine receptor subunit alpha 1 0.0121 0.0447 0.0449
Brugia malayi sulfakinin receptor protein 0.0075 0.0259 0.026
Mycobacterium tuberculosis Probable esterase LipL 0.0106 0.0387 0.1417
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0121 0.0447 0.0449
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0106 0.0387 0.4384
Onchocerca volvulus 0.0065 0.0218 0.0268
Schistosoma mansoni neuropeptide receptor 0.0075 0.0259 0.026
Brugia malayi Dopamine receptor protein 1 0.0075 0.0259 0.026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.0387 0.0389
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0078 0.0776
Onchocerca volvulus 0.0121 0.0447 0.0547
Echinococcus granulosus G protein coupled receptor 139 0.0075 0.0259 0.026
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.0007 0.0072
Echinococcus multilocularis tyrosine kinase 0.0019 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.034 0.1345 0.1352
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0019 0.014
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0075 0.0259 0.026
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.034 0.1345 0.1352
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.011 0.011
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0031 0.023
Onchocerca volvulus Putative neutral sphingomyelinase 0.0012 0 0.0001
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0012 0.0003 0.0018
Brugia malayi Death domain containing protein 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0027 0.006 0.0061
Echinococcus multilocularis lamin 0.0082 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0308 0.1213 0.1219
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0259 0.026
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0259 0.026
Brugia malayi intermediate filament protein 0.0082 0.0288 0.0289
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0027 0.0037
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0122 0.1206
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.042 1
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0027 0.0027
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0115 0.0422
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0646 0.6397
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trypanosoma cruzi mitochondrial protein 99, putative 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.101 1
Echinococcus multilocularis glutamate receptor 2 0.0157 0.0594 0.0594
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0121 0.0447 0.0449
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0075 0.0259 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Loa Loa (eye worm) hypothetical protein 0.0265 0.1039 0.1045
Onchocerca volvulus 0.0075 0.0259 0.0317
Loa Loa (eye worm) inositol-1 0.0112 0.0411 0.0413
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0078 0.4074
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0121 0.0447 0.0449
Toxoplasma gondii hypothetical protein 0.034 0.1345 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0078 0.0776
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0042 0.0419
Echinococcus granulosus neuropeptide receptor A26 0.0075 0.0259 0.026
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0115 0.0858
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0012 0.0092
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0019 0.0019
Trypanosoma cruzi mitochondrial protein 99, putative 0.0012 0 0.0001
Mycobacterium tuberculosis Conserved protein 0.0106 0.0387 0.1417
Brugia malayi Cation transporter family protein 0.0121 0.0447 0.0449
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.034 0.1345 0.1352
Loa Loa (eye worm) hypothetical protein 0.0265 0.1039 0.1045
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0115 0.1307
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0056 0.018 0.0181
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.042 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0317 0.125 0.1256
Onchocerca volvulus 0.0265 0.1039 0.1274
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0121 0.0447 0.0449
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis dullard protein, putative 0.0012 0.0003 0.0028
Echinococcus multilocularis vesicular acetylcholine transporter 0.0677 0.2724 0.2724
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0259 0.0259
Schistosoma mansoni survival motor neuron protein 0.0049 0.0151 0.0152
Echinococcus multilocularis 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0065 0.0218 0.022
Loa Loa (eye worm) GABA receptor subunit 0.0065 0.0218 0.022
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0121 0.0447 0.0447
Brugia malayi Cation transporter family protein 0.0265 0.1039 0.1045
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.003 0.0031
Brugia malayi hypothetical protein 0.0056 0.018 0.0181
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0176 0.0672 0.0676
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0027 0.0037
Brugia malayi G-protein coupled receptor 0.0075 0.0259 0.026
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0056 0.018 0.0181
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0007 0.001
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0259 0.0259
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0075 0.0259 0.0259
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0192 0.1905
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0106 0.0387 0.0389
Loa Loa (eye worm) LGC-31 protein 0.0121 0.0447 0.0449
Echinococcus multilocularis serotonin receptor 0.0075 0.0259 0.0259
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0007 0.001
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0192 0.1428
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0012 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.0003
Onchocerca volvulus 0.0075 0.0259 0.0317
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0121 0.0447 0.0449
Brugia malayi Glutamate receptor 1 precursor 0.0157 0.0594 0.0597
Loa Loa (eye worm) hypothetical protein 0.034 0.1345 0.1352
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0 0.0004
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0121 0.0447 0.0449
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0259 0.026
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0014 0.0014
Mycobacterium leprae Probable lipase LipE 0.0106 0.0387 0.9218
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.101 1
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.042 0.4756
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0151 0.0151
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0151 0.0152
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0078 0.0583
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0259 0.0259
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0236 0.0237
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0019 0.003 0.0037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0259 0.026
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0121 0.0447 0.0449
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0192 0.1428
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Echinococcus granulosus g protein coupled receptor 0.0075 0.0259 0.026
Echinococcus multilocularis neuropeptide s receptor 0.0075 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0411 0.0552
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Brugia malayi Doublecortin family protein 0.0041 0.0119 0.0119
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0121 0.0447 0.0449
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0012 0 0.001
Brugia malayi Tachykinin-like peptides receptor 99D 0.0075 0.0259 0.026
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.0259 0.026
Trichomonas vaginalis dullard protein, putative 0.0012 0.0003 0.0028
Echinococcus multilocularis microtubule associated protein 2 0.1423 0.5779 0.5779
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0078 0.0583
Echinococcus multilocularis RUN 0.0041 0.0119 0.0119
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0075 0.0259 0.026
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0115 0.1307
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0106 0.0387 0.1417
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0178 0.0179
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.042 0.0564
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Loa Loa (eye worm) phosphofructokinase 0.0114 0.042 0.0422
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0027 0.0027
Trypanosoma cruzi squalene synthase, putative 0.073 0.294 0.3947
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0165 0.0166
Schistosoma mansoni hypothetical protein 0.0041 0.0119 0.0119
Echinococcus multilocularis nAChR subunit 0.0121 0.0447 0.0447
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.034 0.1345 0.1352
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0115 0.0155
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0075 0.0259 0.0259
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0121 0.0447 0.0447
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0259 0.0259
Brugia malayi hypothetical protein 0.034 0.1345 0.1352
Echinococcus multilocularis orexin receptor type 2 0.0075 0.0259 0.0259
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0 0.0004
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0121 0.0447 0.0449
Onchocerca volvulus Neuropeptide F receptor homolog 0.0075 0.0259 0.0317
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.042 0.0422
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0027 0.0037
Onchocerca volvulus 0.0019 0.003 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0683 0.6767
Echinococcus granulosus somatostatin receptor 0.0075 0.0259 0.026
Brugia malayi Metabotropic glutamate receptor precursor. 0.0019 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0152 0.0575 0.0578
Onchocerca volvulus 0.0056 0.018 0.0221
Schistosoma mansoni biogenic amine receptor 0.0075 0.0259 0.026
Leishmania major hypothetical protein, conserved 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.2004 0.8158 0.8202
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0014 0.0007 0.0007
Schistosoma mansoni neurotransmitter gated ion channel 0.0065 0.0218 0.022
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.0387 0.3836
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0027 0.0037
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0112 0.0411 1
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0019 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0098 0.097
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0259 0.026
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.034 0.1345 0.1345
Brugia malayi GnHR receptor homolog 0.0075 0.0259 0.026
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0259 0.026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0259 0.0259
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0677 0.2724 0.3339
Schistosoma mansoni nAChR subunit 0.0121 0.0447 0.0449
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.001
Echinococcus multilocularis somatostatin receptor 0.0075 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Schistosoma mansoni vesicular amine transporter 0.244 0.9947 1
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0014 0.0007 0.0007
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0014 0.0014
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.042 0.0514
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0115 0.0422
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0121 0.0447 0.0449
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0225 0.0226
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0259 0.026
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0236 0.0237
Schistosoma mansoni opsin-like receptor 0.0075 0.0259 0.026
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0258 0.101 0.1015
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0259 0.026
Echinococcus granulosus vesicular acetylcholine transporter 0.0677 0.2724 0.2738
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0 0.0001
Leishmania major cytochrome p450-like protein 0.0058 0.0189 0.0254
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0259 0.0259
Schistosoma mansoni glutamate receptor kainate 0.0157 0.0594 0.0597
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0265 0.1039 0.1045
Brugia malayi Serotonin receptor 0.0075 0.0259 0.026
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0258 0.101 0.1015
Schistosoma mansoni hypothetical protein 0.0049 0.0151 0.0152
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0012 0 0.0001
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0013 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.0259 0.026
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0121 0.0447 0.0449
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0122 0.1206
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0097 0.0351 0.0353
Echinococcus granulosus intermediate filament protein 0.0082 0.0288 0.0289
Loa Loa (eye worm) cytochrome P450 0.004 0.0115 0.0116
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0114 0.0115
Echinococcus multilocularis g-protein coupled receptor 0.0075 0.0259 0.0259
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0259 0.026
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0259 0.026
Echinococcus granulosus nmda type glutamate receptor 0.0099 0.0359 0.036
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0189 0.0254
Schistosoma mansoni lamin 0.0082 0.0288 0.0289
Echinococcus granulosus nAChR subunit 0.0121 0.0447 0.0449
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.034 0.1345 0.1352
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0075 0.0259 0.026
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.006 0.0446
Entamoeba histolytica recQ family helicase, putative 0.0012 0 0.0005
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0115 0.0155
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni single-minded 0.0052 0.0165 0.0166
Echinococcus multilocularis glutamate receptor 2 0.0113 0.0416 0.0416
Brugia malayi hypothetical protein 0.0017 0.0022 0.0022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.055 0.055
Echinococcus granulosus glutamate NMDA receptor subunit 0.0379 0.1502 0.151
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0192 0.0258
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0176 0.0672 0.0676
Loa Loa (eye worm) hypothetical protein 0.0065 0.0218 0.022
Onchocerca volvulus 0.0019 0.003 0.0037
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0178 0.0178
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0122 0.0122
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0001 0.0001
Onchocerca volvulus 0.0075 0.0259 0.0317
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0078 0.0776
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0024
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0 0.001
Leishmania major squalene synthase, putative 0.073 0.294 0.3947
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.034 0.1345 0.1352
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0259 0.026
Onchocerca volvulus 0.0265 0.1039 0.1274
Onchocerca volvulus 0.0038 0.011 0.0134
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0056 0.0075
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.0259 0.026
Echinococcus granulosus nAChR subunit 0.0065 0.0218 0.022
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0075 0.0259 0.0259
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0112 0.0411 0.4072
Echinococcus multilocularis lamin b receptor 0.009 0.032 0.032
Onchocerca volvulus 0.0075 0.0259 0.0317
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.0351 0.0353
Loa Loa (eye worm) hypothetical protein 0.034 0.1345 0.1352
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni biogenic amine receptor 0.0075 0.0259 0.026
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0387 0.3836
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0018 0.0028 0.0033
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0012 0 0.0001
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0012 0.0003 0.0068
Mycobacterium tuberculosis Probable lipase LipE 0.0106 0.0387 0.1417
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0646 0.6397
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0027 0.0027
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.053 0.053
Schistosoma mansoni microtubule-associated protein tau 0.1423 0.5779 0.5809
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0014 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0115 0.0422
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0012 0 0.0004
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0259 0.0259
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0115 0.0422
Echinococcus multilocularis neuropeptide receptor A26 0.0075 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0019 0.003 0.0031
Echinococcus multilocularis muscleblind protein 0.0152 0.0575 0.0575
Loa Loa (eye worm) solute carrier family 6 member 4 0.2004 0.8158 0.8202
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0121 0.0447 0.0449
Brugia malayi Latrophilin receptor protein 2 0.0097 0.0351 0.0353
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0132 0.0133
Schistosoma mansoni glutamate receptor kainate 0.0157 0.0594 0.0597
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0114 0.0114
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0121 0.0447 0.0449
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.042 0.1537
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0027 0.0037
Brugia malayi vesicular acetylcholine transporter unc-17 0.0677 0.2724 0.2738
Loa Loa (eye worm) hypothetical protein 0.0055 0.0178 0.0179
Echinococcus granulosus fmrfamide receptor 0.0075 0.0259 0.026
Onchocerca volvulus 0.0106 0.0387 0.0475
Loa Loa (eye worm) hypothetical protein 0.0065 0.0218 0.022
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0679 0.2734 1
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0056 0.0075
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0023 0.0023
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0192 0.0193
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.055 0.0553
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0112 0.0411 0.9787
Echinococcus granulosus lamin 0.0082 0.0288 0.0289
Echinococcus multilocularis GPCR, family 2 0.0097 0.0351 0.0351
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni hypothetical protein 0.0227 0.0883 0.0888
Schistosoma mansoni netrin receptor unc5 0.0015 0.0014 0.0014
Onchocerca volvulus 0.0041 0.0119 0.0145
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0115 0.1307
Schistosoma mansoni glutamate receptor NMDA 0.0256 0.1 0.1006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0121 0.0447 0.0449
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0115 0.0422
Echinococcus multilocularis serotonin receptor 0.0075 0.0259 0.0259
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0259 0.026
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni inositol monophosphatase 0.0112 0.0411 0.0413
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0121 0.0447 0.0447
Leishmania major protein kinase, putative 0.0019 0.0028 0.0037
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0259 0.026
Echinococcus granulosus CTD small phosphatase protein like 0.0012 0.0003 0.0003
Brugia malayi putative neuropeptide receptor 0.0075 0.0259 0.026
Brugia malayi Inositol-1 0.0112 0.0411 0.0413
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0259 0.026
Echinococcus granulosus glycine receptor subunit alpha 1 0.0121 0.0447 0.0449
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0019 0.0025
Brugia malayi Protein kinase domain containing protein 0.0015 0.0014 0.0014
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0014 0.0014
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.042 0.0422
Brugia malayi 6-phosphofructokinase 0.0114 0.0421 0.0423
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0121 0.0447 0.0449
Brugia malayi 6-phosphofructokinase 0.0114 0.042 0.0422
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0119 0.0119
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0176 0.0672 0.0676
Leishmania major hypothetical protein, conserved 0.0012 0 0.0001
Echinococcus granulosus sodium and chloride dependent glycine 0.034 0.1345 0.1352
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0075 0.0259 0.0259
Schistosoma mansoni vesicular acetylcholine transporter 0.0677 0.2724 0.2738
Loa Loa (eye worm) hypothetical protein 0.1831 0.745 0.749
Schistosoma mansoni lipoxygenase 0.0107 0.0389 0.0391
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0115 0.0422
Loa Loa (eye worm) glutamate receptor 2 0.0157 0.0594 0.0597
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0018 0.0028 0.0101
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0075 0.0259 0.0259
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0007 0.0072
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0259 0.0259
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0115 0.0422
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0056 0.018 0.0181
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0119 0.0879
Schistosoma mansoni nAChR subunit 0.0121 0.0447 0.0449
Echinococcus granulosus RUN 0.0041 0.0119 0.0119
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0123 0.0123
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0259 0.0259
Leishmania major hypothetical protein, conserved 0.0012 0.0003 0.0004
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0014 0.0014
Echinococcus granulosus g protein coupled receptor 0.0075 0.0259 0.026
Schistosoma mansoni hypothetical protein 0.0012 0.0002 0.0002
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0116 0.0116
Loa Loa (eye worm) melatonin receptor type 1A 0.0075 0.0259 0.026
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0075 0.0259 0.026
Trypanosoma cruzi extracellular receptor, putative 0.0019 0.003 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.042 0.4161
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0031
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0027 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0646 0.6397
Loa Loa (eye worm) hypothetical protein 0.0038 0.0108 0.0108
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0143 0.0192
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0027 0.0037
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0063 0.0208 0.0209
Trypanosoma brucei C-8 sterol isomerase, putative 0.1831 0.745 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Schistosoma mansoni nAChR subunit 0.0056 0.018 0.0181
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0027 0.0027
Brugia malayi ORL1-like opioid receptor 0.0075 0.0259 0.026
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.006 0.0081
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0119 0.0119
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0 0.0001
Echinococcus granulosus arachidonate 5 lipoxygenase 0.018 0.0689 0.0693
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0 0.0002
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0027 0.0037
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Echinococcus granulosus metabotropic glutamate receptor 2 0.0019 0.003 0.0031
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0056 0.018 0.0181
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0056 0.018 0.018
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0056 0.018 0.0181
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0108 0.0109
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.0003
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0014 0.0007 0.0007
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0115 0.0422
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0007 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0115 0.0422
Echinococcus multilocularis nmda type glutamate receptor 0.0161 0.0612 0.0612
Onchocerca volvulus 0.0075 0.0259 0.0317
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0121 0.0447 0.0449
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0014 0.0007 0.0054
Loa Loa (eye worm) hypothetical protein 0.0239 0.093 0.0935
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0115 0.0422
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.042 1
Onchocerca volvulus 0.0075 0.0259 0.0317
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.0351 0.0351
Echinococcus multilocularis allatostatin A receptor 0.0075 0.0259 0.0259
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.001
Echinococcus granulosus neuropeptide s receptor 0.0075 0.0259 0.026
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0056 0.0056
Echinococcus granulosus synaptic vesicle 2 protein 0.0013 0.0005 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0259 0.0259
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0259 0.0259
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0121 0.0447 0.0447
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0575 0.0575
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0121 0.0447 0.0449
Leishmania major hypothetical protein, conserved 0.0027 0.006 0.0081
Brugia malayi Muscleblind-like protein 0.0152 0.0575 0.0578
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0 0.001
Echinococcus granulosus neuropeptide FF receptor 2 0.0075 0.0259 0.026
Brugia malayi PAS domain containing protein 0.0052 0.0165 0.0166
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0106 0.0387 0.0389
Schistosoma mansoni polycystin 1-related 0.0041 0.0119 0.0119
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0259 0.026
Echinococcus granulosus single minded 2 0.0042 0.0124 0.0125
Schistosoma mansoni hypothetical protein 0.0063 0.0208 0.0209
Echinococcus granulosus glycine receptor subunit alpha 1 0.0121 0.0447 0.0449
Echinococcus granulosus atrial natriuretic peptide receptor 0.0019 0.003 0.0031
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0056 0.018 0.0181
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0513 0.0516
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0178 0.0179
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0018 0.0028 0.0033
Loa Loa (eye worm) hypothetical protein 0.004 0.0114 0.0115
Loa Loa (eye worm) CYP4Cod1 0.0058 0.0189 0.019
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0012 0 0.0001
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0007 0.001
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0012 0.0003 0.0018
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0075 0.0259 0.026
Schistosoma mansoni nAChR subunit 0.0056 0.018 0.0181
Schistosoma mansoni amine GPCR 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0106 0.0387 0.0389
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0041
Echinococcus granulosus bloom syndrome protein 0.0022 0.0042 0.0043
Mycobacterium leprae Possible regulatory protein 0.0014 0.0007 0.0172
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.0003
Brugia malayi hypothetical protein 0.0174 0.0666 0.067
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0225 0.0226
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.001
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0379 0.1502 0.1502
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0106 0.0387 0.1417
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0115 0.2748
Trypanosoma brucei squalene synthase, putative 0.073 0.294 0.3947
Loa Loa (eye worm) hypothetical protein 0.2004 0.8158 0.8202
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0387 0.052
Schistosoma mansoni neuropeptide receptor 0.0075 0.0259 0.026
Brugia malayi beta-lactamase family protein 0.0106 0.0387 0.0389
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.055 0.0553
Trypanosoma brucei RNA editing exonuclease 2 0.0012 0 0.0001
Brugia malayi Receptor family ligand binding region containing protein 0.0019 0.003 0.0031
Echinococcus multilocularis aryl hydrocarbon receptor 0.0014 0.0007 0.0007
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.003 0.0031
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0259 0.026
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0259 0.026
Echinococcus multilocularis geminin 0.1221 0.4955 0.4955
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0143 0.0192
Echinococcus granulosus serotonin transporter 0.2004 0.8158 0.8202
Echinococcus multilocularis receptor type guanylyl cyclase 0.0019 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0097 0.0351 0.0353
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni hypothetical protein 0.021 0.0814 0.0818
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0288 0.0289
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0063 0.0208 0.0209
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0225 0.0226
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0203 0.0785 0.0785
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Onchocerca volvulus 0.0075 0.0259 0.0317
Brugia malayi Sodium:neurotransmitter symporter family protein 0.034 0.1345 0.1352
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0098 0.097
Loa Loa (eye worm) hypothetical protein 0.0939 0.3798 0.3818
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0227 0.0883 0.0888
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0236 0.5623
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0259 0.0259
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0108 0.0109
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.006 0.0446
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0646 0.6397
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0027 0.0651
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0012 0.0003 0.0148
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Echinococcus multilocularis G protein coupled receptor 139 0.0075 0.0259 0.0259
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0081 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0065 0.0218 0.022
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0078 0.0583
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0259 0.0259
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0115 0.1307
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0308 0.1213 0.1219
Schistosoma mansoni neuropeptide f receptor 76f 0.0075 0.0259 0.026
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0121 0.0447 0.0449
Loa Loa (eye worm) norepinephrine transporter 0.2004 0.8158 0.8202
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0119 0.0119
Leishmania major sterol C-24 reductase, putative 0.0047 0.0143 0.0192
Loa Loa (eye worm) hypothetical protein 0.021 0.0814 0.0818
Schistosoma mansoni glutamate receptor AMPA 0.0157 0.0594 0.0597
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.004 0.0115 0.1307
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0078 0.0776
Schistosoma mansoni neurotransmitter gated ion channel 0.0056 0.018 0.0181
Onchocerca volvulus 0.0075 0.0259 0.0317
Echinococcus multilocularis nAChR subunit 0.0065 0.0218 0.0218
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.042 0.4161
Onchocerca volvulus 0.0075 0.0259 0.0317
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0075 0.0259 0.026
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0178 0.0179
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0013 0.0005 0.0053
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.034 0.1345 0.1352
Schistosoma mansoni opsin-like receptor 0.0075 0.0259 0.026
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0115 0.1307
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0078 0.058
Trypanosoma brucei hypothetical protein, conserved 0.0106 0.0387 0.052
Loa Loa (eye worm) hypothetical protein 0.0936 0.3784 0.3804
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0151 0.0152
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0288 0.0289
Echinococcus granulosus hypothetical protein 0.0075 0.0259 0.026
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0027 0.0203
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0026
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0151 0.0151
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.034 0.1345 1
Brugia malayi hypothetical protein 0.0041 0.0119 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Plasmodium falciparum transporter, putative 0.034 0.1345 1
Schistosoma mansoni hypothetical protein 0.1221 0.4955 0.4981
Brugia malayi hypothetical protein 0.0041 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0081 0.0282 0.0283
Treponema pallidum sodium- and chloride- dependent transporter 0.2004 0.8158 1
Leishmania major RNA-editing complex protein MP100, putative 0.0012 0 0.0001
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0236 0.0317
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0121 0.0447 0.0449
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0075 0.0259 0.026
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0176 0.0672 0.0672
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.101 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0259 0.026
Echinococcus multilocularis synaptic vesicle 2 protein 0.0013 0.0005 0.0005
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0056 0.018 0.018
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0097 0.0351 0.0353
Echinococcus multilocularis glycine receptor subunit beta 0.0121 0.0447 0.0447
Entamoeba histolytica hypothetical protein 0.0025 0.0056 0.1322
Loa Loa (eye worm) hypothetical protein 0.0606 0.2435 0.2448
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0012 0.0003 0.0028
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0041 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0259 0.026
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0192 0.2178
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0078 0.0776
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Echinococcus granulosus receptor type guanylyl cyclase 0.0019 0.003 0.0031
Schistosoma mansoni hypothetical protein 0.004 0.0115 0.0116
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0012 0.0003 0.0003
Brugia malayi bHLH-PAS transcription factor 0.0038 0.011 0.011
Schistosoma mansoni histamine h1 receptor 0.0075 0.0259 0.026
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0225 0.0226
Brugia malayi Cytochrome P450 family protein 0.0058 0.0189 0.019
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0014 0.0017
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.0351 0.0353
Loa Loa (eye worm) hypothetical protein 0.0065 0.0218 0.022
Trypanosoma cruzi squalene synthase, putative 0.073 0.294 0.3947
Brugia malayi hypothetical protein 0.0239 0.093 0.0935
Brugia malayi hypothetical protein 0.0056 0.018 0.0181
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0646 0.6397
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0027 0.0037
Schistosoma mansoni alpha-1 adrenergic receptor 0.0075 0.0259 0.026
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.034 0.1345 0.1352
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0027 0.0027
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0019 0.0137
Echinococcus granulosus transcription factor Dp 1 0.004 0.0116 0.0117
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0259 0.0259
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0027 0.0037
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0019 0.0025
Brugia malayi Cytochrome P450 family protein 0.0058 0.0189 0.019
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0259 0.026
Echinococcus multilocularis nmda type glutamate receptor 0.0099 0.0359 0.0359
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0012 0 0.0001
Loa Loa (eye worm) hypoxia-induced factor 1 0.0161 0.0611 0.0614
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0078 0.1865
Mycobacterium ulcerans esterase/lipase LipP 0.0106 0.0387 0.4384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0115 0.1307
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0218 0.022
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0019 0.003 0.0031
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0007 0.001
Onchocerca volvulus 0.0075 0.0259 0.0317
Leishmania major pantothenate kinase subunit, putative 0.0012 0 0.0001
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0012 0 0.0004
Echinococcus multilocularis serotonin transporter 0.2004 0.8158 0.8158
Echinococcus multilocularis Squalene phytoene synthase 0.0227 0.0883 0.0883
Loa Loa (eye worm) hypothetical protein 0.034 0.1345 0.1352
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.055 0.0553
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0225 0.0226
Echinococcus granulosus muscleblind protein 0.0152 0.0575 0.0578
Brugia malayi Serotonin receptor 0.0075 0.0259 0.026
Toxoplasma gondii ABC1 family protein 0.0106 0.0387 0.288
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0019 0.0069
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0014 0.0007 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0259 0.026
Brugia malayi Sodium:neurotransmitter symporter family protein 0.034 0.1345 0.1352
Brugia malayi hypoxia-induced factor 1 0.0161 0.0611 0.0614
Echinococcus multilocularis neuropeptide FF receptor 2 0.0075 0.0259 0.0259
Brugia malayi Sodium:neurotransmitter symporter family protein 0.034 0.1345 0.1352
Loa Loa (eye worm) hypothetical protein 0.0152 0.0575 0.0578
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0056 0.055
Brugia malayi isocitrate dehydrogenase 0.0016 0.0019 0.0019
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0027 0.0651
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni inositol monophosphatase 0.0112 0.0411 0.0413
Schistosoma mansoni glutamate receptor NMDA 0.0379 0.1502 0.151
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.001
Echinococcus granulosus neuropeptide receptor 0.0075 0.0259 0.026
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0121 0.0447 0.0447
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0 0.0001
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0027 0.0027
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0115 0.1307
Echinococcus multilocularis sex peptide receptor 0.0075 0.0259 0.0259
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0007 0.0072
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0019 0.014
Echinococcus granulosus nmda type glutamate receptor 0.0161 0.0612 0.0615
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.244 0.9947 1
Mycobacterium tuberculosis Conserved protein 0.0106 0.0387 0.1417
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.101 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0115 0.0155
Plasmodium vivax hypothetical protein, conserved 0.0106 0.0387 0.2877
Echinococcus granulosus tachykinin peptides receptor 99D 0.0075 0.0259 0.026
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0123 0.0123
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0019 0.0019
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0115 0.1307
Trypanosoma cruzi phytoene synthase, putative 0.0227 0.0883 0.1186
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0056 0.018 0.018
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0121 0.0447 0.0449
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0012 0 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0259 0.026
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0012 0 0.0004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0259 0.0259
Echinococcus multilocularis lamin dm0 0.0082 0.0288 0.0288
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.006 0.0081
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0259 0.026
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.0351 0.0353
Onchocerca volvulus 0.0082 0.0288 0.0353
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0078 0.0776
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0236 0.0317
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0259 0.0259
Schistosoma mansoni nAChR subunit 0.0121 0.0447 0.0449
Loa Loa (eye worm) glutamate receptor 1 0.0157 0.0594 0.0597
Brugia malayi hypothetical protein 0.0056 0.018 0.0181
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0146 0.055 0.0553
Echinococcus multilocularis G-protein coupled receptor, putative 0.0075 0.0259 0.0259
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.034 0.1345 0.1352
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0115 0.0422
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Echinococcus granulosus serotonin receptor 0.0075 0.0259 0.026
Schistosoma mansoni sodium/chloride dependent transporter 0.034 0.1345 0.1352
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0218 0.022
Schistosoma mansoni amine GPCR 0.0075 0.0259 0.026
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.006 0.0081
Echinococcus granulosus glutamate receptor 2 0.0113 0.0416 0.0418
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.0259 0.026
Echinococcus multilocularis musashi 0.0082 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0031
Mycobacterium ulcerans phytoene synthase, CrtB 0.0227 0.0883 1
Mycobacterium ulcerans hypothetical protein 0.0106 0.0387 0.4384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Onchocerca volvulus Glucosylceramidase homolog 0.0169 0.0646 0.0792
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0075 0.0259 0.026
Leishmania major cytochrome p450-like protein 0.004 0.0115 0.0155
Schistosoma mansoni cytochrome P450 0.004 0.0115 0.0116
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0056 0.0056
Schistosoma mansoni neurotransmitter gated ion channel 0.0056 0.018 0.0181
Schistosoma mansoni hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis Phospholipase C precursor, putative 0.0012 0 0.0004
Echinococcus granulosus beta LACTamase domain containing family member 0.0106 0.0387 0.0389
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0259 0.026
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0 0.0004
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.034 0.1345 0.1352
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0007 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0115 0.0422
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0007 0.001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0192 0.0258
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.01 0.0363 0.8641
Echinococcus granulosus geminin 0.1221 0.4955 0.4981
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.034 0.1345 0.1345
Brugia malayi RNA binding protein 0.0067 0.0225 0.0226
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0027 0.0027
Schistosoma mansoni metabotropic glutamate receptor 0.0019 0.003 0.0031
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.034 0.1345 1
Brugia malayi larval opioid receptor 0.0075 0.0259 0.026
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0151 0.0152
Schistosoma mansoni hypothetical protein 0.0075 0.0259 0.026
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0115 0.0422
Schistosoma mansoni glutamate receptor kainate 0.0157 0.0594 0.0597
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Trypanosoma brucei C-14 sterol reductase, putative 0.009 0.032 0.0429
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni acetylcholine receptor subunit beta 0.0056 0.018 0.0181
Loa Loa (eye worm) hypothetical protein 0.0049 0.0151 0.0152
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0065 0.0218 0.022
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0189 0.0254
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0115 0.0422
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0259 0.026
Schistosoma mansoni ap endonuclease 0.0059 0.0192 0.0193
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0288 0.0289
Leishmania major hypothetical protein, conserved 0.0106 0.0387 0.052
Loa Loa (eye worm) ACC-1 protein 0.0121 0.0447 0.0449
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0078 0.0096
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0031
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0007 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.101 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0075 0.0259 0.026
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0027 0.0037
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.018 0.0689 0.0689
Echinococcus granulosus 7TM GPCR rhodopsin 0.0075 0.0259 0.026
Loa Loa (eye worm) serotonin transporter b 0.2004 0.8158 0.8202
Loa Loa (eye worm) hypothetical protein 0.0082 0.0288 0.0289
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0411 0.0552
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0078 0.058
Onchocerca volvulus 0.0075 0.0259 0.0317
Onchocerca volvulus 0.0041 0.0119 0.0145
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.034 0.1345 0.1352
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0225 0.0226
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0259 0.026
Echinococcus granulosus metabotropic glutamate receptor 5 0.0019 0.003 0.0031
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0108 0.0109
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Giardia lamblia Inositol 5-phosphatase 4 0.0012 0 0.0022
Echinococcus granulosus glutamate receptor subunit protein glur 0.0063 0.0208 0.0209
Schistosoma mansoni protein kinase 0.0019 0.003 0.0031
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0042 0.0042
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1145 0.4643 0.4643
Brugia malayi mbt repeat family protein 0.0049 0.0151 0.0152
Brugia malayi Cation transporter family protein 0.0121 0.0447 0.0449
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1831 0.745 0.749
Brugia malayi phosphofructokinase 0.0114 0.042 0.0422
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Schistosoma mansoni amine GPCR 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0031
Schistosoma mansoni nAChR subunit 0.0121 0.0447 0.0449
Toxoplasma gondii hypothetical protein 0.034 0.1345 1
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0115 0.0422
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0192 0.4579
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.042 0.0564
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0203 0.0785 0.0789
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0014 0.0014
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0677 0.2724 0.2738
Schistosoma mansoni myosin xvIII 0.0075 0.0259 0.026
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0308 0.1213 0.1219
Echinococcus granulosus tar DNA binding protein 0.0067 0.0225 0.0226
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0031
Echinococcus granulosus aryl hydrocarbon receptor 0.0014 0.0007 0.0007
Schistosoma mansoni sodium/chloride dependent transporter 0.2004 0.8158 0.8202
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0106 0.0387 0.0389
Echinococcus multilocularis sodium and chloride dependent glycine 0.034 0.1345 0.1345
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Schistosoma mansoni growth hormone secretagogue receptor 0.0075 0.0259 0.026
Trypanosoma cruzi C-14 sterol reductase, putative 0.009 0.032 0.0429
Onchocerca volvulus 0.0049 0.0151 0.0185
Onchocerca volvulus 0.0121 0.0447 0.0547
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0121 0.0447 0.0447
Onchocerca volvulus 0.0121 0.0447 0.0547
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0075 0.0259 0.0259
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0012 0.0003 0.0003
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0056 0.018 0.0181
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0121 0.0447 0.0449
Brugia malayi hypothetical protein 0.0056 0.018 0.0181
Echinococcus granulosus g protein coupled receptor 0.0075 0.0259 0.026
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0259 0.026
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0075 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0065 0.0218 0.022
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0121 0.0447 0.0449
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0259 0.026
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0115 0.0155
Echinococcus granulosus glutamate receptor 2 0.0176 0.0672 0.0676
Plasmodium vivax hypothetical protein, conserved 0.034 0.1345 1
Brugia malayi follicle stimulating hormone receptor 0.0317 0.125 0.1256
Brugia malayi hypothetical protein 0.0027 0.006 0.0061
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0259 0.0259
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0121 0.0447 0.0449
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0115 0.1307
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0259 0.0259
Schistosoma mansoni metabotropic glutamate receptor 0.0019 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0387 0.3836
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0259 0.026
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0075 0.0259 0.026
Brugia malayi Calcitonin receptor-like protein seb-1 0.0308 0.1213 0.1219
Onchocerca volvulus 0.0065 0.0218 0.0268
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.101 1
Brugia malayi cytochrome P450 0.004 0.0115 0.0116
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0176 0.0672 0.0672
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0192 0.0193
Leishmania major C-8 sterol isomerase-like protein 0.1831 0.745 1
Echinococcus granulosus sodium and chloride dependent glycine 0.034 0.1345 0.1352
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0019 0.0019
Echinococcus granulosus alpha 1A adrenergic receptor 0.0075 0.0259 0.026
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0225 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0192 1
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0121 0.0447 0.0447
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0012 0.0003 0.0018
Brugia malayi hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0007 0.0072
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0236 0.0237
Giardia lamblia hypothetical protein 0.0012 0 0.0022
Schistosoma mansoni intermediate filament proteins 0.0082 0.0288 0.0289
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0012 0 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0007 0.0072
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0192 0.1905
Echinococcus multilocularis glutamate receptor NMDA 0.008 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.034 0.1345 0.1352
Onchocerca volvulus 0.0075 0.0259 0.0317
Brugia malayi Uncoordinated protein 44 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0007 0.0072
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0259 0.026
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0447 0.0449
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0236 0.0317
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0056 0.018 0.0181
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0119 0.0879
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0108 0.0797
Echinococcus granulosus g-protein coupled receptor 0.0075 0.0259 0.026
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0012 0 0.0001
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0192 0.0192
Schistosoma mansoni nAChR subunit 0.0121 0.0447 0.0449
Mycobacterium tuberculosis Probable lipase LipD 0.0106 0.0387 0.1417
Onchocerca volvulus Putative nachr subunit 0.0121 0.0447 0.0547
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0027 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0646 0.6397
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni acetylcholine receptor-related 0.0056 0.018 0.0181
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0227 0.0883 0.1083
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0012 0.0003 0.0021
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0132 0.0133
Brugia malayi neuropeptide F receptor 0.0075 0.0259 0.026
Onchocerca volvulus 0.0265 0.1039 0.1274
Onchocerca volvulus 0.0056 0.018 0.0221
Schistosoma mansoni hypothetical protein 0.0097 0.0351 0.0353
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni amine GPCR 0.0075 0.0259 0.026
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0056 0.0056
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.042 0.0422
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0259 0.026
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.042 0.4161
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0683 0.6767
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Schistosoma mansoni Lamin B receptor (ERG24) 0.009 0.032 0.0322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0 0.0001
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0121 0.0447 0.0449
Schistosoma mansoni hypothetical protein 0.0097 0.0351 0.0353
Schistosoma mansoni ATP-binding cassette transporter 0.0157 0.0594 0.0597
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.0387 0.3836
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0112 0.0411 0.4072
Schistosoma mansoni hypothetical protein 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0088 0.0088
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0121 0.0447 0.0449
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0115 0.0422
Loa Loa (eye worm) RNA binding protein 0.0067 0.0225 0.0226
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0106 0.0387 0.0389
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0106 0.0387 0.0389
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0115 0.0422
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.042 0.0422
Loa Loa (eye worm) beta-lactamase 0.0106 0.0387 0.0389
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0019 0.003 0.0031
Echinococcus granulosus inositol monophosphatase 1 0.0112 0.0411 0.0413
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.0351 0.0351
Schistosoma mansoni biogenic amine receptor 0.0075 0.0259 0.026
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0078 0.0776
Schistosoma mansoni nAChR subunit 0.0121 0.0447 0.0449
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0115 0.1307
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.055 0.0553
Brugia malayi metabotropic glutamate receptor type 2 0.0019 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Onchocerca volvulus 0.0049 0.0151 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0012 0.0003 0.0003
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0115 0.0155
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0259 0.0259
Echinococcus multilocularis synaptic vesicular amine transporter 0.244 0.9947 0.9947
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0007 0.001
Mycobacterium tuberculosis Conserved protein 0.0106 0.0387 0.1417
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0019 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.042 0.4161
Onchocerca volvulus 0.0056 0.018 0.0221
Onchocerca volvulus 0.034 0.1345 0.1649
Giardia lamblia GTOR 0.0018 0.0027 0.1421
Echinococcus multilocularis Ankyrin 0.0015 0.0014 0.0014
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.034 0.1345 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0112 0.0411 0.4655
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0063 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.053 0.0532
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0151 0.0152
Onchocerca volvulus 0.0075 0.0259 0.0317
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0019 0.0137
Onchocerca volvulus 0.0075 0.0259 0.0317
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0115 0.0116
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0112 0.0411 0.0552
Mycobacterium ulcerans putative regulatory protein 0.0038 0.011 0.124
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0078 0.0583
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0 0.0001
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0075 0.0259 0.026
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0056 0.018 0.0181
Echinococcus granulosus Squalene phytoene synthase 0.0227 0.0883 0.0888
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.053 0.0532
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0063 0.0208 0.0208
Schistosoma mansoni lamin 0.0082 0.0288 0.0289
Mycobacterium tuberculosis Probable exported protein 0.0012 0 0.0002
Loa Loa (eye worm) MBCTL1 0.0055 0.0178 0.0179
Echinococcus multilocularis beta LACTamase domain containing family member 0.0106 0.0387 0.0387
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0019 0.0019
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0018 0.0028 0.0205
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0115 0.1307
Loa Loa (eye worm) TYRA-2 protein 0.0075 0.0259 0.026
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0108 0.5594
Brugia malayi mbt repeat family protein 0.0049 0.0151 0.0152
Brugia malayi Guanylyl cyclase protein 23 0.0019 0.003 0.0031
Brugia malayi Cytochrome P450 family protein 0.0078 0.0272 0.0274
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0151 0.0152
Loa Loa (eye worm) hypothetical protein 0.021 0.0811 0.0815
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0027 0.0037
Echinococcus multilocularis glutamate receptor 2 0.0176 0.0672 0.0672
Leishmania major protein kinase, putative 0.0014 0.0007 0.001
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0176 0.0672 0.0672
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0 0.0001
Schistosoma mansoni rab6-interacting 0.0041 0.0119 0.0119
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.093 0.093
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0075 0.0259 0.026
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0122 0.0903
Echinococcus granulosus peptide allatostatin:somatostatin 0.0075 0.0259 0.026
Schistosoma mansoni tyrosine kinase 0.0019 0.003 0.0031
Trichomonas vaginalis dullard protein, putative 0.0012 0.0003 0.0028
Plasmodium falciparum amino acid transporter, putative 0.034 0.1345 1
Echinococcus multilocularis NMDA receptor 0.0063 0.0208 0.0208
Schistosoma mansoni rab6-interacting 0.0041 0.0119 0.0119
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0115 0.0422
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0176 0.0672 0.0672
Echinococcus granulosus dro:myosuppressin receptor 0.0075 0.0259 0.026
Echinococcus granulosus uncharacterized sodium dependent transporter 0.034 0.1345 0.1352
Entamoeba histolytica hypothetical protein 0.0065 0.0218 0.5198
Loa Loa (eye worm) hypothetical protein 0.0065 0.0218 0.022
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.042 0.042
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0115 0.1307
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0122 0.0905
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0189 0.019
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0225 0.0226
Loa Loa (eye worm) hypothetical protein 0.0106 0.0387 0.0389
Schistosoma mansoni hypothetical protein 0.0053 0.0168 0.0169
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0259 0.026
Echinococcus granulosus lamin b receptor 0.009 0.032 0.0322
Echinococcus granulosus uncharacterized sodium dependent transporter 0.034 0.1345 0.1352
Schistosoma mansoni nAChR subunit 0.0121 0.0447 0.0449
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0019 0.0025
Echinococcus multilocularis glycine receptor subunit beta 0.0121 0.0447 0.0447
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0106 0.0387 0.1417
Mycobacterium leprae conserved hypothetical protein 0.0106 0.0387 0.9218
Echinococcus multilocularis dro:myosuppressin receptor 0.0075 0.0259 0.0259
Leishmania major cytochrome p450-like protein 0.004 0.0115 0.0155
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0012 0 0.001
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0119 0.0119
Schistosoma mansoni opsin-like receptor 0.0075 0.0259 0.026
Schistosoma mansoni ap endonuclease 0.0059 0.0192 0.0193
Echinococcus granulosus microtubule associated protein 2 0.1423 0.5779 0.5809
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0272 0.0274
Brugia malayi hypothetical protein 0.0019 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0056 0.018 0.0181
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0056 0.018 0.0181
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Echinococcus granulosus lamin dm0 0.0082 0.0288 0.0289
Echinococcus granulosus synaptic vesicular amine transporter 0.244 0.9947 1
Loa Loa (eye worm) ACC-1 protein 0.0121 0.0447 0.0449
Loa Loa (eye worm) acetylcholine receptor protein 0.0056 0.018 0.0181
Plasmodium vivax amine transporter, putative 0.034 0.1345 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0178 0.0179
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0121 0.0447 0.0449
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0003 0.0004
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0192 0.0235
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.042 1
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0012 0.0003 0.0028
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0 0.0001
Brugia malayi hypothetical protein 0.0606 0.2435 0.2448
Loa Loa (eye worm) hypothetical protein 0.0121 0.0447 0.0449
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0065 0.0218 0.022
Onchocerca volvulus 0.0606 0.2435 0.2985
Leishmania major hypothetical protein, conserved 0.0012 0 0.0001
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0151 0.0152
Schistosoma mansoni adenoreceptor 0.0075 0.0259 0.026
Leishmania major hypothetical protein, conserved 0.0227 0.0883 0.1186
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0075 0.0259 0.026
Onchocerca volvulus 0.0012 0 0.0001
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0121 0.0447 0.0449
Schistosoma mansoni sodium/chloride dependent transporter 0.034 0.1345 0.1352
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0119 0.0119
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.055 0.0553
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0192 0.0704
Brugia malayi RE15519p 0.0075 0.0259 0.026
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0018 0.0028 0.0312
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.034 0.1345 0.1345
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.034 0.1345 0.1352
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0259 0.026
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0 0.0001
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.042 0.0564
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0265 0.1039 0.1045
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0027 0.0037
Brugia malayi Glutamate receptor 2 precursor 0.0157 0.0594 0.0597
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0108 0.2562
Mycobacterium tuberculosis Probable hydrolase 0.0106 0.0387 0.1417
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0012 0 0.001
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0115 0.1307
Loa Loa (eye worm) hypothetical protein 0.0174 0.0666 0.067
Loa Loa (eye worm) hypothetical protein 0.0075 0.0259 0.026
Loa Loa (eye worm) hypothetical protein 0.0065 0.0218 0.022
Leishmania major endonuclease/exonuclease protein-like protein 0.0012 0 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0027 0.0271

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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