Detailed information for compound 1064691

Basic information

Technical information
  • TDR Targets ID: 1064691
  • Name: 3-cyclopentyl-N-(2,4,6-trimethylphenyl)propan amide
  • MW: 259.386 | Formula: C17H25NO
  • H donors: 1 H acceptors: 1 LogP: 4.68 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1c(C)cc(cc1C)C)CCC1CCCC1
  • InChi: 1S/C17H25NO/c1-12-10-13(2)17(14(3)11-12)18-16(19)9-8-15-6-4-5-7-15/h10-11,15H,4-9H2,1-3H3,(H,18,19)
  • InChiKey: BUUTYLFHZZXVTC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-cyclopentyl-N-(2,4,6-trimethylphenyl)propionamide
  • ZINC00364444

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Voltage-gated potassium channel subunit Kv7.2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis potassium voltage gated channel subfamily KQT Get druggable targets OG5_129255 All targets in OG5_129255
Echinococcus granulosus potassium channel KvQLT family member kqt 1 Get druggable targets OG5_129255 All targets in OG5_129255
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129255 All targets in OG5_129255
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog Get druggable targets OG5_129255 All targets in OG5_129255
Schistosoma japonicum ko:K04927 potassium voltage-gated channel, KQT-like subfamily, member 2, putative Get druggable targets OG5_129255 All targets in OG5_129255
Schistosoma mansoni voltage-gated potassium channel KCNQ Get druggable targets OG5_129255 All targets in OG5_129255
Loa Loa (eye worm) voltage-gated potassium channel Get druggable targets OG5_129255 All targets in OG5_129255
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 Get druggable targets OG5_129255 All targets in OG5_129255
Schistosoma japonicum ko:K05324 potassium voltage-gated channel, KQT-like subfamily, invertebrate, putative Get druggable targets OG5_129255 All targets in OG5_129255
Echinococcus granulosus potassium voltage gated channel subfamily KQT Get druggable targets OG5_129255 All targets in OG5_129255
Echinococcus multilocularis potassium voltage gated channel subfamily KQT Get druggable targets OG5_129255 All targets in OG5_129255
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129255 All targets in OG5_129255
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0019 0.007 0.0063
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0783 0.0832
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0026 0.0146 0.0188
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0026 0.0146 0.1339
Echinococcus multilocularis geminin 0.0897 1 1
Schistosoma mansoni smad1 5 8 and 0.002 0.0076 0.0061
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0026 0.0146 0.0164
Loa Loa (eye worm) hypothetical protein 0.0087 0.0832 0.126
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.011 0.0816
Echinococcus granulosus pyruvate kinase 0.0017 0.004 0.0024
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0101 0.0086
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0066 0.06 0.1447
Loa Loa (eye worm) hypothetical protein 0.0115 0.1152 0.1755
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0094 0.0909 0.1623
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0555 0.0541
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0327 0.0485
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.038 0.0571
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0032 0.0016
Plasmodium falciparum glutathione reductase 0.0032 0.0215 0.1902
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0611 0.0596
Brugia malayi Glycosyl hydrolases family 31 protein 0.0054 0.0462 0.0712
Loa Loa (eye worm) hypothetical protein 0.0111 0.111 0.169
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0022 0.0101 0.0039
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0019 0.007 0.0561
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0203 0.0187
Onchocerca volvulus 0.0019 0.007 0.01
Brugia malayi GnHR receptor homolog 0.0016 0.0029 0.0045
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0026 0.0146 0.013
Echinococcus multilocularis expressed protein 0.0022 0.0101 0.0085
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Echinococcus granulosus g protein coupled receptor 0.0016 0.0029 0.0013
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0171 0.0033
Echinococcus multilocularis tar DNA binding protein 0.0386 0.4218 0.4209
Schistosoma mansoni hypothetical protein 0.0029 0.018 0.0165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0029 0.0014
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0203 0.0346
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0203 0.0288
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0016 0.0029 0.002
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0171 0.1448
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0064 0.0579 0.0658
Echinococcus granulosus fmrfamide receptor 0.0016 0.0029 0.0013
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0101 0.0039
Brugia malayi latrophilin 2 splice variant baaae 0.0373 0.4067 0.627
Brugia malayi hypothetical protein 0.0022 0.0101 0.0156
Entamoeba histolytica heat shock transcription factor, putative 0.0115 0.1152 0.14
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0152 0.1573 0.1559
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0026 0.0146 0.022
Onchocerca volvulus 0.0022 0.0101 0.0158
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0022 0.0101 0.0132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0702 0.7799 0.9744
Schistosoma mansoni ran 0.0023 0.011 0.0095
Schistosoma mansoni histamine h1 receptor 0.0016 0.0029 0.0014
Onchocerca volvulus 0.0022 0.0101 0.0158
Trichomonas vaginalis maltase-glucoamylase, putative 0.002 0.0078 0.001
Schistosoma mansoni survival motor neuron protein 0.012 0.1204 0.119
Echinococcus granulosus neuropeptide receptor A26 0.0476 0.5231 0.5223
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.027 0.0255
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0026 0.0146 0.0147
Schistosoma mansoni coup transcription factor 0.0031 0.0203 0.0188
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.01 0.0982 0.1492
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0073 0.0087
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0029 0.0013
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0327 0.037
Onchocerca volvulus 0.0339 0.3684 0.6815
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0029 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0518 0.5708 0.5701
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0032 0.0016
Brugia malayi hypothetical protein 0.049 0.5398 0.8321
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0036 0.0263 0.0381
Plasmodium falciparum pyruvate kinase 0.0033 0.022 0.1955
Brugia malayi putative neuropeptide receptor 0.0016 0.0029 0.0045
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0087 0.0832 0.126
Mycobacterium ulcerans hypothetical protein 0.0066 0.06 0.1026
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.002 0.0078 0.001
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0032 0.0016
Leishmania major acetyl-CoA synthetase, putative 0.0019 0.007 0.0105
Onchocerca volvulus 0.0016 0.0029 0.0024
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0073 0.0679 0.6713
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0995 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0016 0.0029 0.0013
Onchocerca volvulus 0.0087 0.0832 0.1515
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Brugia malayi Calcitonin receptor-like protein seb-1 0.0545 0.6019 0.9279
Schistosoma mansoni Smad4 0.002 0.0076 0.0061
Schistosoma mansoni biogenic amine receptor 0.0016 0.0029 0.0014
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0291 0.0511
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0016 0.0029 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0462 0.0705
Plasmodium vivax hypothetical protein, conserved 0.0029 0.018 0.1532
Entamoeba histolytica hypothetical protein 0.0058 0.0504 0.0561
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0094 0.0909 0.912
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0518 0.5708 0.5701
Onchocerca volvulus 0.0016 0.0029 0.0024
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0022 0.0101 0.0132
Loa Loa (eye worm) hypothetical protein 0.0545 0.6019 0.9277
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0026 0.0146 0.0226
Entamoeba histolytica heat shock transcription factor, putative 0.0115 0.1152 0.14
Schistosoma mansoni lamin 0.01 0.0982 0.0968
Brugia malayi MH2 domain containing protein 0.002 0.0076 0.0117
Trypanosoma cruzi hypothetical protein, conserved 0.0054 0.0462 0.4559
Toxoplasma gondii aldehyde dehydrogenase 0.0476 0.524 1
Onchocerca volvulus 0.0016 0.0029 0.0024
Toxoplasma gondii exonuclease III APE 0.0042 0.0327 0.0567
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0029 0.0013
Echinococcus granulosus expressed conserved protein 0.0094 0.0915 0.09
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0066 0.06 0.1026
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0026 0.0146 0.0096
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0702 0.7799 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0203 0.0313
Brugia malayi Probable ClpP-like protease 0.0082 0.0783 0.1207
Loa Loa (eye worm) hypothetical protein 0.0101 0.0995 0.1513
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.2075 0.2528
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0327 0.0324
Plasmodium vivax importin-beta 2, putative 0.0031 0.0204 0.1786
Toxoplasma gondii propionate-CoA ligase 0.0019 0.007 0.0074
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.022 0.034
Echinococcus granulosus g-protein coupled receptor 0.0016 0.0029 0.0013
Schistosoma mansoni opsin-like receptor 0.0016 0.0029 0.0014
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0026 0.0146 0.0147
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0029 0.0013
Onchocerca volvulus Neuropeptide F receptor homolog 0.0016 0.0029 0.0024
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0054 0.0462 0.0689
Brugia malayi nuclear receptor NHR-88 0.0031 0.0203 0.0313
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Echinococcus granulosus pyruvate kinase 0.0033 0.022 0.0204
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.1471 0.1457
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0016 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.038 0.0571
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 3 0.0073 0.0679 0.1046
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0016 0.0029 0.0045
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0082 0.0783 0.8349
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0087 0.0832 0.1473
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0078 0.001
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0019 0.007 0.0063
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0026 0.0146 0.022
Trichomonas vaginalis ran, putative 0.0023 0.011 0.0051
Echinococcus multilocularis chromobox protein 1 0.007 0.0638 0.0622
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0058 0.0504 0.0488
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0029 0.002
Echinococcus multilocularis snurportin 1 0.0334 0.363 0.362
Brugia malayi HSF-type DNA-binding domain containing protein 0.0115 0.1152 0.1776
Plasmodium vivax sphingomyelin synthase 1, putative 0.0073 0.0679 0.6713
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0518 0.5708 0.5701
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0019 0.007 0.0083
Brugia malayi Smad1 0.002 0.0076 0.0117
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0078 0.001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0555
Echinococcus granulosus serotonin receptor 0.0016 0.0029 0.0013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0029 0.0013
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0094 0.0909 0.1685
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0029 0.0014
Brugia malayi Latrophilin receptor protein 2 0.0172 0.1802 0.2778
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0174 0.1815 0.1802
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0026 0.0146 0.0201
Loa Loa (eye worm) hypothetical protein 0.0022 0.0101 0.0132
Mycobacterium leprae Probable lipase LipE 0.0087 0.0832 0.208
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0016 0.0001
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0014
Schistosoma mansoni neuropeptide receptor 0.0016 0.0029 0.0014
Entamoeba histolytica acyl-CoA synthetase, putative 0.0066 0.06 0.0686
Echinococcus granulosus Smad4 0.002 0.0076 0.006
Brugia malayi Heterochromatin protein 1 0.007 0.0638 0.0983
Brugia malayi hypothetical protein 0.0016 0.0036 0.0056
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0022 0.0101 0.0156
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0031
Leishmania major 4-coumarate:coa ligase-like protein 0.0066 0.06 0.112
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0026 0.0146 0.0147
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0074 0.0683 0.1069
Echinococcus multilocularis musashi 0.01 0.0982 0.0967
Echinococcus granulosus hypothetical protein 0.0016 0.0029 0.0013
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0066 0.06 0.1026
Brugia malayi Dopamine receptor protein 1 0.0016 0.0029 0.0045
Loa Loa (eye worm) pax transcription factor protein 2 0.0255 0.2733 0.4199
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0026 0.0146 0.0164
Onchocerca volvulus 0.0016 0.0029 0.0024
Echinococcus multilocularis serotonin receptor 0.0016 0.0029 0.0013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0029 0.0014
Trichomonas vaginalis D-aminoacylase, putative 0.0087 0.0832 0.096
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0032 0.0215 0.0301
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0203 0.0313
Echinococcus multilocularis smad 0.002 0.0076 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.03 0.3242 0.3998
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0054 0.0462 0.0826
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0101 0.0039
Leishmania major 4-coumarate:coa ligase-like protein 0.0066 0.06 0.112
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0016 0.0029 0.0013
Echinococcus granulosus potassium voltage gated channel subfamily KQT 0.0078 0.0734 0.0719
Loa Loa (eye worm) pyruvate kinase 0.0033 0.022 0.0315
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0087 0.0832 0.1313
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0203 0.0288
Loa Loa (eye worm) MBCTL1 0.0042 0.032 0.0469
Leishmania major pyruvate kinase 0.0033 0.022 0.0392
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0029 0.0014
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0172 0.1802 0.1788
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0702 0.7799 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.011 0.0091
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0203 0.0188
Brugia malayi beta-lactamase family protein 0.0087 0.0832 0.1282
Schistosoma mansoni tyrosine kinase 0.018 0.1892 0.188
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0203 0.0288
Echinococcus multilocularis serotonin receptor 0.0016 0.0029 0.0013
Plasmodium falciparum sphingomyelin synthase 2, putative 0.0073 0.0679 0.6713
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0022 0.0101 0.0085
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0026 0.0146 0.013
Echinococcus granulosus 7TM GPCR rhodopsin 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0073 0.0679 0.1024
Echinococcus multilocularis orexin receptor type 2 0.0016 0.0029 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0203 0.0313
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0327 0.0504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0026 0.0146 0.013
Echinococcus granulosus survival motor neuron protein 1 0.0586 0.6487 0.6481
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0026 0.0146 0.0147
Loa Loa (eye worm) MH2 domain-containing protein 0.002 0.0076 0.0092
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0203 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0679 0.0767
Echinococcus granulosus thioredoxin glutathione reductase 0.0032 0.0215 0.0199
Schistosoma mansoni GTP-binding protein alpha subunit 0.0022 0.0101 0.0086
Loa Loa (eye worm) hypothetical protein 0.0087 0.0832 0.126
Loa Loa (eye worm) hypothetical protein 0.0029 0.018 0.0252
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0029 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Echinococcus granulosus tachykinin peptides receptor 99D 0.0016 0.0029 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0203 0.0313
Brugia malayi hypothetical protein 0.0586 0.6487 1
Leishmania major phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0073 0.0679 0.127
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0016 0.0029 0.002
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0041 0.0038
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0327 0.048
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0016 0.0029 0.0013
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0049 0.0405 0.0389
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0476 0.524 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0343 0.3733 0.6075
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0171 0.1448
Schistosoma mansoni pyruvate kinase 0.0033 0.022 0.0205
Loa Loa (eye worm) hypothetical protein 0.01 0.0984 0.1496
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0032 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0386 0.4218 0.421
Leishmania major pyruvate kinase 0.0033 0.022 0.0392
Mycobacterium ulcerans beta-lactamase 0.0087 0.0832 0.1473
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0343 0.3733 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Schistosoma mansoni sex comb on midleg homolog 0.0036 0.0263 0.0248
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.1002 0.0988
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Schistosoma mansoni tyrosine kinase 0.018 0.1892 0.188
Schistosoma mansoni spingomyelin synthetase-related 0.0073 0.0679 0.0664
Brugia malayi Inositol-1 0.0094 0.0909 0.1402
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0203 0.0313
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0019 0.007 0.0108
Loa Loa (eye worm) hypothetical protein 0.0039 0.029 0.0423
Schistosoma mansoni zinc finger protein 0.0015 0.0016 0.0001
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0094 0.0909 0.1119
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0036 0.002
Trichomonas vaginalis sphingomyelin synthetase, putative 0.072 0.8002 1
Plasmodium falciparum thioredoxin reductase 0.0032 0.0215 0.1902
Schistosoma mansoni chromobox protein 0.007 0.0638 0.0623
Brugia malayi hypothetical protein 0.0016 0.0036 0.0056
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0462 0.0446
Entamoeba histolytica acyl-coA synthetase, putative 0.0066 0.06 0.0686
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0036 0.002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0101 0.0132
Echinococcus multilocularis Protein lozenge 0.0042 0.0331 0.0315
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.007 0.0063
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0051 0.0426 0.0758
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0066 0.06 0.0933
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0203 0.0188
Loa Loa (eye worm) MH2 domain-containing protein 0.0294 0.3172 0.4876
Schistosoma mansoni aldehyde dehydrogenase 0.0026 0.0146 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.2075 0.2528
Schistosoma mansoni nuclear receptor 0.0015 0.0016 0.0001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0087 0.0832 0.0818
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0204 0.0236
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0204 0.0236
Echinococcus granulosus intermediate filament protein 0.01 0.0982 0.0967
Mycobacterium ulcerans aldehyde dehydrogenase 0.0476 0.524 1
Schistosoma mansoni chromobox protein 0.007 0.0638 0.0623
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.018 0.0284
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0026 0.0146 0.0201
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0858 0.9564 0.9563
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0702 0.7799 0.9744
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.06 0.1026
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0016 0.0001
Schistosoma mansoni GTP-binding protein alpha subunit 0.0022 0.0101 0.0086
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0022 0.0101 0.0132
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Trypanosoma brucei inositol phosphorylceramide synthase 0.072 0.8002 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0101 0.0132
Echinococcus granulosus pyruvate kinase 0.0033 0.022 0.0204
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0029 0.0013
Schistosoma mansoni ran 0.0023 0.011 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0426 0.0412
Trichomonas vaginalis glucosylceramidase, putative 0.03 0.3242 0.3998
Schistosoma mansoni myosin xvIII 0.0016 0.0029 0.0014
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0984 0.1517
Leishmania major GTP-binding protein, putative 0.0023 0.011 0.0182
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0073 0.0679 0.0767
Onchocerca volvulus Glucosylceramidase homolog 0.0197 0.2075 0.3826
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0327 0.3065
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0203 0.0187
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0203 0.0188
Onchocerca volvulus 0.01 0.0982 0.1794
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0087 0.0832 0.0818
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0554 0.6124 1
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0082 0.0783 0.7798
Onchocerca volvulus 0.0016 0.0029 0.0024
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0019 0.007 0.0063
Brugia malayi neuropeptide F receptor 0.0016 0.0029 0.0045
Loa Loa (eye worm) hypothetical protein 0.0098 0.0961 0.146
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0203 0.0313
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Giardia lamblia Pyruvate kinase 0.0033 0.022 0.0232
Trichomonas vaginalis chromobox protein, putative 0.007 0.0638 0.0715
Echinococcus granulosus lamin 0.01 0.0982 0.0967
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.038 0.0571
Schistosoma mansoni tyrosine kinase 0.0108 0.1078 0.1064
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.018 0.0165
Loa Loa (eye worm) aldehyde dehydrogenase 0.0026 0.0146 0.0201
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0016 0.0029 0.0014
Loa Loa (eye worm) hypothetical protein 0.0064 0.0579 0.087
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Schistosoma mansoni smad1 5 8 and 0.002 0.0076 0.0061
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0054 0.0462 0.0494
Leishmania major aldehyde dehydrogenase, putative 0.0026 0.0146 0.0251
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0171 0.0276
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0026 0.0146 0.0099
Loa Loa (eye worm) hypothetical protein 0.0031 0.0203 0.0288
Loa Loa (eye worm) hypothetical protein 0.0339 0.3684 0.5668
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0152 0.1573 0.1559
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0022 0.0101 0.0085
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0026 0.0146 0.0188
Brugia malayi Glycosyl hydrolases family 31 protein 0.002 0.0078 0.012
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0337 0.0321
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0702 0.7799 0.9744
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0133 0.135 0.2061
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.06 0.0933
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0026 0.0146 0.022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0702 0.7799 0.9744
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0022 0.0101 0.0086
Schistosoma mansoni alpha-1 adrenergic receptor 0.0016 0.0029 0.0014
Loa Loa (eye worm) hypothetical protein 0.0586 0.6487 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0702 0.7799 0.9744
Echinococcus multilocularis chromobox protein 1 0.007 0.0638 0.0622
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.022 0.2092
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0094 0.0077
Loa Loa (eye worm) hypothetical protein 0.005 0.0411 0.0609
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0518 0.5708 0.5701
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0172 0.1802 0.1788
Brugia malayi sulfakinin receptor protein 0.0016 0.0029 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0073 0.0679 0.0663
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0182 0.1914 0.1901
Trypanosoma cruzi hypothetical protein, conserved 0.0087 0.0832 0.8332
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0203 0.0187
Brugia malayi AMP-binding enzyme family protein 0.0019 0.007 0.0108
Schistosoma mansoni hypothetical protein 0.0172 0.1802 0.1789
Brugia malayi putative neuropeptide receptor NPR1 0.0016 0.0029 0.0045
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0073 0.0679 0.6713
Schistosoma mansoni growth hormone secretagogue receptor 0.0016 0.0029 0.0014
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.011 0.0145
Schistosoma mansoni hypothetical protein 0.012 0.1204 0.119
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Brugia malayi RNA, U transporter 1 0.0089 0.0857 0.1321
Loa Loa (eye worm) TYRA-2 protein 0.0016 0.0029 0.002
Brugia malayi aldehyde dehydrogenase 0.0026 0.0146 0.0226
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0026 0.0146 0.013
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0016 0.0025
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0016 0.0029 0.0014
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0066 0.06 0.1447
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0026 0.0146 0.0164
Echinococcus granulosus sex peptide receptor 0.0016 0.0029 0.0013
Brugia malayi chromobox protein homolog 3 0.0039 0.0291 0.0449
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.005 0.0411 0.3381
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0203 0.0188
Brugia malayi Pax transcription factor protein 2 0.0255 0.2733 0.4213
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0029 0.0014
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0029 0.0014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0029 0.0013
Echinococcus multilocularis sex peptide receptor 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0203 0.0288
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0203 0.0187
Echinococcus multilocularis lamin 0.01 0.0982 0.0967
Plasmodium falciparum pyruvate kinase 2 0.0017 0.004 0.0084
Onchocerca volvulus 0.0087 0.0832 0.1515
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0032 0.0017
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.002 0.0078 0.0639
Brugia malayi jmjC domain containing protein 0.0037 0.027 0.0415
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0203 0.0187
Trichomonas vaginalis chromobox protein, putative 0.007 0.0638 0.0715
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0026 0.0146 0.013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0203 0.0288
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0108 0.1078 0.1063
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0036 0.0056
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0014
Onchocerca volvulus 0.0062 0.0555 0.1002
Brugia malayi G-protein coupled receptor 0.0016 0.0029 0.0045
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0034 0.0238 0.0222
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0984 0.0969
Brugia malayi N-terminal motif family protein 0.0111 0.111 0.1711
Giardia lamblia Fructose-bisphosphate aldolase 0.0702 0.7799 1
Brugia malayi nuclear receptor NHR-67 0.0015 0.0016 0.0025
Loa Loa (eye worm) hypothetical protein 0.0043 0.0337 0.0495
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0026 0.0146 0.0147
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0325 0.0321
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0327 0.0311
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0016 0.0029 0.002
Brugia malayi nuclear hormone receptor 0.0015 0.0016 0.0025
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0984 0.0969
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0029 0.0013
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0032 0.0016
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0022 0.0101 0.0085
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0016 0.0029 0.0013
Echinococcus granulosus importin subunit beta 1 0.0031 0.0204 0.0188
Loa Loa (eye worm) oxidoreductase 0.0019 0.007 0.0083
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0042 0.032 0.0304
Loa Loa (eye worm) hypothetical protein 0.0031 0.0204 0.029
Onchocerca volvulus 0.0016 0.0029 0.0024
Echinococcus multilocularis neutral alpha glucosidase AB 0.0054 0.0462 0.0446
Trichomonas vaginalis sucrase-isomaltase, putative 0.0054 0.0462 0.0494
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0203 0.0288
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0026 0.0146 0.0131
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0019 0.007 0.0063
Schistosoma mansoni amine GPCR 0.0016 0.0029 0.0014
Onchocerca volvulus 0.0087 0.0832 0.1515
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0016 0.0029 0.0013
Brugia malayi CHE-14 protein 0.0043 0.0337 0.0519
Echinococcus granulosus histone lysine methyltransferase setb 0.0067 0.0611 0.0595
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0082 0.0776 0.1927
Echinococcus granulosus tar DNA binding protein 0.0386 0.4218 0.4209
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.005 0.0411 0.0609
Schistosoma mansoni opsin-like receptor 0.0016 0.0029 0.0014
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Onchocerca volvulus 0.0016 0.0029 0.0024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0203 0.0187
Schistosoma mansoni hypothetical protein 0.0041 0.0319 0.0304
Brugia malayi Sphingomyelin synthase-related 1 0.0073 0.0679 0.1046
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.2075 0.2528
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.007 0.0108
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0203 0.0188
Schistosoma mansoni hypothetical protein 0.0897 1 1
Leishmania major alpha glucosidase II subunit, putative 0.0054 0.0462 0.0855
Trichomonas vaginalis glucosylceramidase, putative 0.0207 0.2195 0.2679
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0026 0.0146 0.0147
Mycobacterium tuberculosis Conserved protein 0.0087 0.0832 0.1313
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0016 0.0029 0.0014
Echinococcus granulosus lysosomal alpha glucosidase 0.0244 0.2609 0.2597
Echinococcus multilocularis 0.0105 0.1039 0.1024
Schistosoma mansoni neuropeptide f receptor 76f 0.0016 0.0029 0.0014
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0327 0.3065
Loa Loa (eye worm) hypothetical protein 0.0033 0.022 0.0315
Loa Loa (eye worm) runx1 0.0042 0.0331 0.0486
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0019 0.007 0.0069
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0343 0.334
Loa Loa (eye worm) hypothetical protein 0.0068 0.0614 0.0924
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0203 0.0187
Onchocerca volvulus 0.0016 0.0029 0.0024
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0019 0.007 0.0561
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0108 0.0049
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0016 0.0029 0.0013
Loa Loa (eye worm) transcription factor SMAD2 0.0294 0.3172 0.4876
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0327 0.0597
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.027 0.0254
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0518 0.5708 0.8796
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0462 0.0494
Loa Loa (eye worm) hypothetical protein 0.005 0.0411 0.0609
Echinococcus granulosus mothers against decapentaplegic 5 0.002 0.0076 0.006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0203 0.0187
Loa Loa (eye worm) hypothetical protein 0.0073 0.0679 0.1024
Echinococcus multilocularis pyruvate kinase 0.0026 0.0142 0.0126
Schistosoma mansoni aldehyde dehydrogenase 0.0026 0.0146 0.0131
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0203 0.0188
Schistosoma mansoni tar DNA-binding protein 0.0386 0.4218 0.421
Brugia malayi Intermediate filament tail domain containing protein 0.01 0.0982 0.1514
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Mycobacterium tuberculosis Probable dehydrogenase 0.0074 0.0683 0.1069
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Brugia malayi Glycosyl hydrolases family 31 protein 0.0244 0.2609 0.4022
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0026 0.0146 0.0164
Echinococcus multilocularis neuropeptide s receptor 0.0476 0.5231 0.5223
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Schistosoma mansoni ap endonuclease 0.0042 0.0327 0.0312
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0337 0.0321
Brugia malayi hypothetical protein 0.0101 0.0995 0.1535
Loa Loa (eye worm) hypothetical protein 0.0558 0.6162 0.9498
Schistosoma mansoni alpha-glucosidase 0.021 0.2225 0.2213
Brugia malayi AMP-binding enzyme family protein 0.0019 0.007 0.0108
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0029 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0078 0.001
Leishmania major cathepsin L-like protease 0.0044 0.0343 0.0627
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0029 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Echinococcus granulosus g protein coupled receptor 0.0016 0.0029 0.0013
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0026 0.0146 0.1339
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0022 0.0101 0.0085
Loa Loa (eye worm) hypothetical protein 0.0037 0.0265 0.0384
Loa Loa (eye worm) hypothetical protein 0.0073 0.0679 0.1024
Brugia malayi hypothetical protein 0.0339 0.3684 0.5679
Schistosoma mansoni aldehyde dehydrogenase 0.0026 0.0146 0.0131
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0026 0.0146 0.0099
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0032 0.0016
Echinococcus multilocularis neuropeptide FF receptor 2 0.0016 0.0029 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Entamoeba histolytica hypothetical protein 0.0073 0.0679 0.0787
Onchocerca volvulus 0.0066 0.06 0.1085
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0386 0.4218 0.6494
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0094 0.0909 0.1086
Schistosoma mansoni opsin-like receptor 0.0016 0.0029 0.0014
Echinococcus granulosus 7tm_1 domain containing protein 0.0016 0.0029 0.0013
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0026 0.0146 0.0099
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0476 0.524 0.5232
Onchocerca volvulus 0.0016 0.0029 0.0024
Echinococcus granulosus allatostatin A receptor 0.0016 0.0029 0.0013
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0325 0.0573
Mycobacterium ulcerans esterase/lipase LipP 0.0087 0.0832 0.1473
Echinococcus multilocularis protein dispatched 1 0.0049 0.0405 0.039
Loa Loa (eye worm) hypothetical protein 0.0087 0.0832 0.126
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0094 0.0909 0.1058
Schistosoma mansoni importin beta-1 0.0031 0.0204 0.0189
Loa Loa (eye worm) hypothetical protein 0.0023 0.0108 0.0142
Loa Loa (eye worm) hypothetical protein 0.0031 0.0203 0.0288
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0073 0.0679 0.6769
Onchocerca volvulus 0.0016 0.0029 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.03 0.3242 0.3998
Trypanosoma cruzi major cysteine proteinase, putative 0.0034 0.0237 0.2264
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0019 0.007 0.0074
Echinococcus granulosus peptide allatostatin:somatostatin 0.0016 0.0029 0.0013
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0057 0.0495 0.048
Loa Loa (eye worm) hypothetical protein 0.0172 0.1802 0.276
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0203 0.0288
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0026 0.0146 0.013
Schistosoma mansoni biogenic amine receptor 0.0016 0.0029 0.0014
Echinococcus multilocularis pyruvate kinase 0.0033 0.022 0.0204
Echinococcus granulosus microtubule associated protein 2 0.069 0.7653 0.7649
Echinococcus granulosus polycomb protein SCMH1 0.0036 0.0263 0.0247
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0029 0.0013
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0174 0.1815 0.2798
Onchocerca volvulus 0.0019 0.007 0.01
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.022 0.0379
Toxoplasma gondii ABC1 family protein 0.0087 0.0832 0.1536
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0022 0.0101 0.0085
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0462 0.0494
Trypanosoma brucei trypanothione reductase 0.0032 0.0215 0.025
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0026 0.0146 0.0147
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0411 0.0659
Mycobacterium ulcerans pyruvate kinase 0.0033 0.022 0.029
Brugia malayi Pre-SET motif family protein 0.0355 0.387 0.5965
Trichomonas vaginalis inositol monophosphatase, putative 0.0094 0.0909 0.1058
Brugia malayi Thioredoxin reductase 0.0032 0.0215 0.0332
Loa Loa (eye worm) hypothetical protein 0.0046 0.0375 0.0555
Brugia malayi jmjC domain containing protein 0.0095 0.093 0.1433
Brugia malayi AMP-binding enzyme family protein 0.0066 0.06 0.0925
Loa Loa (eye worm) hypothetical protein 0.0031 0.0203 0.0288
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0019 0.007 0.0063
Mycobacterium tuberculosis Conserved protein 0.0087 0.0832 0.1313
Echinococcus multilocularis survival motor neuron protein 1 0.0586 0.6487 0.6481
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0032 0.0024
Echinococcus multilocularis TGF beta signal transducer SmadC 0.002 0.0076 0.006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0476 0.524 1
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0073 0.0679 0.1046
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0327 0.0324
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.0201
Brugia malayi isocitrate dehydrogenase 0.0016 0.0032 0.0049
Schistosoma mansoni transcription factor LCR-F1 0.0058 0.0504 0.0489
Trypanosoma cruzi cruzipain precursor, putative 0.0044 0.0343 0.334
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0073 0.0679 0.0767
Loa Loa (eye worm) mbt repeat family protein 0.0036 0.0263 0.0381
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.022 0.0189
Brugia malayi nuclear receptor RXR 0.0015 0.0016 0.0025
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0026 0.0146 0.1339
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.022 0.0362
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0783 1
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0029 0.0013
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0026 0.0146 0.0188
Brugia malayi beta-lactamase family protein 0.0087 0.0832 0.1282
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0708 0.0693
Schistosoma mansoni bromodomain containing protein 0.006 0.0534 0.0519
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0022 0.0101 0.0156
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0082 0.0776 0.1221
Brugia malayi RNA recognition motif domain containing protein 0.0386 0.4218 0.6503
Loa Loa (eye worm) hypothetical protein 0.049 0.5398 0.8317
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0337 0.0495
Echinococcus multilocularis somatostatin receptor 0.0016 0.0029 0.0013
Brugia malayi Importin beta-1 subunit 0.0031 0.0204 0.0314
Echinococcus granulosus lamin dm0 0.01 0.0982 0.0967
Plasmodium vivax acyl-CoA synthetase, putative 0.005 0.0411 0.3931
Loa Loa (eye worm) hypothetical protein 0.0022 0.0101 0.0132
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Echinococcus granulosus zinc finger protein 0.0019 0.0061 0.0045
Echinococcus multilocularis polycomb protein SCMH1 0.0036 0.0263 0.0247
Echinococcus multilocularis pyruvate kinase 0.0017 0.004 0.0024
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0054 0.0462 0.0507
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0702 0.7799 0.9744
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0172 0.1802 0.1788
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0082 0.0783 0.1947
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0343 0.3733 0.7086
Schistosoma mansoni ap endonuclease 0.0042 0.0327 0.0312
Echinococcus granulosus TGF beta signal transducer SmadC 0.002 0.0076 0.006
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0343 0.334
Schistosoma mansoni pyruvate kinase 0.0033 0.022 0.0205
Echinococcus granulosus neuropeptide FF receptor 2 0.0016 0.0029 0.0013
Brugia malayi mbt repeat family protein 0.0036 0.0263 0.0405
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0022 0.0101 0.0086
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0026 0.0146 0.1339
Brugia malayi Dopamine receptor 0.0016 0.0029 0.0045
Schistosoma mansoni tyrosine kinase 0.0182 0.1914 0.1902
Loa Loa (eye worm) hypothetical protein 0.0042 0.032 0.0469
Loa Loa (eye worm) latrophilin receptor protein 2 0.0172 0.1802 0.276
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0026 0.0146 0.1339
Onchocerca volvulus 0.0016 0.0029 0.0024
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0026 0.0146 0.1339
Echinococcus multilocularis G-protein coupled receptor, putative 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0016 0.0029 0.0013
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.007 0.0063
Loa Loa (eye worm) hypothetical protein 0.0373 0.4067 0.6261
Brugia malayi RNA binding protein 0.0386 0.4218 0.6503
Echinococcus multilocularis G protein coupled receptor 139 0.0016 0.0029 0.0013
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.011 0.0816
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0203 0.0187
Loa Loa (eye worm) hypothetical protein 0.0031 0.0203 0.0288
Echinococcus multilocularis protein patched 0.0043 0.0337 0.0321
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0036 0.0021
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0327 0.0311
Brugia malayi Cytochrome P450 family protein 0.0037 0.0273 0.042
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0031
Schistosoma mansoni tyrosine kinase 0.0108 0.1078 0.1064
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.0995 0.1227
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0203 0.0188
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0026 0.0146 0.0242
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0026 0.0146 0.0226
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.0995 0.185
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.0278
Onchocerca volvulus 0.0016 0.0029 0.0024
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0203 0.0313
Echinococcus granulosus neuropeptide receptor 0.0016 0.0029 0.0013
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0334 0.363 0.5585
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0078 0.0734 0.0719
Echinococcus granulosus smad 0.002 0.0076 0.006
Mycobacterium ulcerans hypothetical protein 0.0087 0.0832 0.1473
Echinococcus granulosus pyruvate kinase 0.0017 0.004 0.0024
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.007 0.0063
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0026 0.0146 0.1339
Leishmania major hypothetical protein, conserved 0.0101 0.0995 0.1876
Echinococcus multilocularis histone acetyltransferase MYST2 0.0042 0.032 0.0304
Schistosoma mansoni amine GPCR 0.0016 0.0029 0.0014
Plasmodium falciparum importin beta, putative 0.0031 0.0204 0.1786
Brugia malayi MH2 domain containing protein 0.002 0.0076 0.0117
Echinococcus granulosus neutral alpha glucosidase AB 0.0054 0.0462 0.0446
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0016 0.0029 0.0014
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0022 0.0101 0.0132
Loa Loa (eye worm) voltage-gated potassium channel 0.0171 0.1782 0.2728
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0995 1
Brugia malayi mbt repeat family protein 0.0036 0.0263 0.0405
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0078 0.001
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0016 0.0025
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.011 0.0094
Treponema pallidum fructose-bisphosphate aldolase 0.0702 0.7799 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0203 0.0187
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0462 0.0494
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Loa Loa (eye worm) thioredoxin reductase 0.0032 0.0215 0.0307
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0029 0.0013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0029 0.0014
Mycobacterium tuberculosis Probable lipase LipD 0.0087 0.0832 0.1313
Echinococcus granulosus chromobox protein 1 0.007 0.0638 0.0622
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0249 0.0233
Schistosoma mansoni smad1 5 8 and 0.002 0.0076 0.0061
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0101 0.0039
Echinococcus granulosus sphingomyelin synthase protein 1 0.0073 0.0679 0.0663
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.012 0.1204 0.1855
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0016 0.0029 0.0013
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.007 0.0063
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.004 0.03 0.2904
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0036 0.0263 0.0248
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0026 0.0146 0.0208
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0462 0.0494
Brugia malayi hypothetical protein 0.0133 0.135 0.2081
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0026 0.0146 0.1339
Schistosoma mansoni amine GPCR 0.0016 0.0029 0.0014
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0203 0.0187
Trypanosoma cruzi hypothetical protein, conserved 0.0087 0.0832 0.8332
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0204 0.033
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0016 0.0029 0.0014
Schistosoma mansoni amine GPCR 0.0016 0.0029 0.0014
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0022 0.0101 0.0086
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0057 0.0495 0.048
Brugia malayi Melatonin receptor type 1A 0.0016 0.0029 0.0045
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0026 0.0146 0.0251
Echinococcus granulosus snurportin 1 0.0334 0.363 0.362
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0203 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0337 0.0336
Loa Loa (eye worm) G protein alpha subunit 3 0.0022 0.0101 0.0132
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0327 0.3183
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0029 0.0013
Leishmania major importin beta-1 subunit, putative 0.0025 0.0137 0.0233
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0058 0.0504 0.0488
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0032 0.0021
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0174 0.1815 0.1802
Echinococcus granulosus g protein coupled receptor 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0026 0.0146 0.0188
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0016 0.0029 0.0014
Brugia malayi G-protein coupled receptor 0.0016 0.0029 0.0045
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.03 0.3242 0.4984
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0042 0.032 0.0304
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0309 0.0293
Echinococcus multilocularis pyruvate kinase 0.0033 0.022 0.0204
Loa Loa (eye worm) Smad1 0.002 0.0076 0.0092
Brugia malayi Bromodomain containing protein 0.0031 0.0205 0.0316
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0026 0.0146 0.013
Leishmania major hypothetical protein, conserved 0.0087 0.0832 0.1563
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.0133 0.135 0.2061
Brugia malayi hypothetical protein 0.0058 0.0504 0.0777
Echinococcus multilocularis epidermal growth factor receptor 0.034 0.3692 0.3682
Onchocerca volvulus Huntingtin homolog 0.0133 0.135 0.2478
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0325 0.0321
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0042 0.032 0.0493
Brugia malayi MH1 domain containing protein 0.002 0.0076 0.0117
Trichomonas vaginalis set domain proteins, putative 0.0404 0.4425 0.549
Brugia malayi AMP-binding enzyme family protein 0.0019 0.007 0.0108
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.005 0.0411 0.0622
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0108 0.0142
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0364 0.0348
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.022 0.0309
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0203 0.0313
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0026 0.0146 0.0208
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0029 0.0014
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0031
Loa Loa (eye worm) hypothetical protein 0.0048 0.0396 0.0587
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0783 1
Trichomonas vaginalis D-aminoacylase, putative 0.0087 0.0832 0.096
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0019 0.007 0.0063
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0094 0.0077
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0984 0.1182
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0026 0.0146 0.0147
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0016 0.0034 0.0018
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.011 0.0094
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0203 0.0188
Brugia malayi Muscleblind-like protein 0.0558 0.6162 0.9499
Toxoplasma gondii hypothetical protein 0.0073 0.0679 0.1242
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0026 0.0146 0.1339
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0016 0.0029 0.0045
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0016 0.0029 0.0045
Onchocerca volvulus 0.0016 0.0029 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0087 0.0832 0.096
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.002 0.0078 0.001
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0022 0.0101 0.0156
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.018 0.0284
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0087 0.0832 0.1282
Echinococcus granulosus expressed protein 0.0022 0.0101 0.0085
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Onchocerca volvulus 0.0031 0.0196 0.0334
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.004 0.0016
Echinococcus granulosus beta LACTamase domain containing family member 0.0087 0.0832 0.0817
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0203 0.0313
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.022 0.0379
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.002 0.0078 0.001
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0204 0.0188
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0034 0.0238 0.0222
Brugia malayi G protein-coupled receptor 0.0016 0.0029 0.0045
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0017 0.004 0.0013
Loa Loa (eye worm) RNA binding protein 0.0386 0.4218 0.6494
Loa Loa (eye worm) TAR-binding protein 0.0386 0.4218 0.6494
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0016 0.0025
Echinococcus granulosus histone acetyltransferase MYST2 0.0042 0.032 0.0304
Entamoeba histolytica Ran family GTPase 0.0023 0.011 0.0052
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0032 0.017
Brugia malayi RE15519p 0.0016 0.0029 0.0045
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0203 0.0188
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0022 0.0101 0.0086
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.1471 0.1457
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0094 0.0909 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0327 0.0236
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0101 0.0156
Trypanosoma brucei hypothetical protein, conserved 0.0087 0.0832 0.1023
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0172 0.1802 0.1789
Plasmodium vivax SET domain protein, putative 0.0051 0.0426 0.4095
Loa Loa (eye worm) hypothetical protein 0.0022 0.0101 0.0132
Echinococcus granulosus SAM and MBT domain containing protein 0.0036 0.0263 0.0247
Schistosoma mansoni hypothetical protein 0.0041 0.0319 0.0304
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0082 0.0776 0.1221
Brugia malayi AMP-binding enzyme family protein 0.0066 0.06 0.0925
Brugia malayi AMP-binding enzyme family protein 0.0066 0.06 0.0925
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0019 0.007 0.0105
Schistosoma mansoni neuropeptide receptor 0.0016 0.0029 0.0014
Echinococcus multilocularis Smad4 0.002 0.0076 0.006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0311 0.0455
Trypanosoma brucei glucosidase, putative 0.0054 0.0462 0.056
Schistosoma mansoni sex comb on midleg homolog 0.0036 0.0263 0.0248
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0036 0.0031
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0518 0.5708 0.5701
Brugia malayi Dopamine receptor protein 2 0.0016 0.0029 0.0045
Loa Loa (eye worm) hypothetical protein 0.01 0.0982 0.1492
Trichomonas vaginalis glucosylceramidase, putative 0.03 0.3242 0.3998
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0203 0.0187
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0029 0.002
Leishmania major aldehyde dehydrogenase, putative 0.0026 0.0146 0.0251
Schistosoma mansoni tyrosine kinase 0.018 0.1892 0.188
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0022 0.0101 0.0086
Loa Loa (eye worm) hypothetical protein 0.0039 0.0291 0.0425
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0022 0.0101 0.0156
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0019 0.007 0.0561
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0014
Echinococcus multilocularis g-protein coupled receptor 0.0016 0.0029 0.0013
Trichomonas vaginalis hypothetical protein 0.0073 0.0679 0.0767
Loa Loa (eye worm) hypothetical protein 0.0087 0.0832 0.126
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0026 0.0146 0.0147
Echinococcus granulosus epidermal growth factor receptor 0.034 0.3692 0.3682
Trichomonas vaginalis penicillin-binding protein, putative 0.0087 0.0832 0.096
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0026 0.0146 0.022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0203 0.0288
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0029 0.0013
Schistosoma mansoni hypothetical protein 0.0172 0.1802 0.1789
Brugia malayi larval opioid receptor 0.0016 0.0029 0.0045
Onchocerca volvulus 0.0022 0.0101 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0203 0.0288
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.06 0.1026
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.011 0.017
Schistosoma mansoni tar DNA-binding protein 0.0386 0.4218 0.421
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0309 0.0293
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0337 0.0321
Trichomonas vaginalis sphingomyelin synthetase, putative 0.072 0.8002 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0016 0.0001
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0783 0.1443
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0036 0.0021
Schistosoma mansoni nuclear receptor 0.0015 0.0016 0.0001
Echinococcus multilocularis epidermal growth factor receptor 0.0182 0.1914 0.1901
Echinococcus multilocularis GPCR, family 2 0.0172 0.1802 0.1788
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0163 0.0116
Echinococcus granulosus inositol monophosphatase 1 0.0094 0.0909 0.0894
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0101 0.0156
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0137 0.1242
Brugia malayi G protein-coupled receptor F59B2.13 0.0016 0.0029 0.0045
Schistosoma mansoni hypothetical protein 0.0045 0.0364 0.0349
Brugia malayi hypothetical protein 0.0015 0.0016 0.0025
Plasmodium vivax thioredoxin reductase, putative 0.0032 0.0215 0.1902
Echinococcus multilocularis zinc finger protein 0.0019 0.0061 0.0045
Echinococcus multilocularis dro:myosuppressin receptor 0.0016 0.0029 0.0013
Entamoeba histolytica hypothetical protein 0.0025 0.0137 0.0086
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0022 0.0101 0.0085
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0029 0.0013
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0034 0.0019
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0036 0.0056
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Mycobacterium tuberculosis Probable lipase LipE 0.0087 0.0832 0.1313
Leishmania major glycosyl hydrolase-like protein 0.002 0.0078 0.012
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0026 0.0146 0.0188
Brugia malayi AKH receptor 0.0016 0.0029 0.0045
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.018 0.0252
Giardia lamblia PHD finger protein 15 0.0029 0.018 0.018
Schistosoma mansoni hypothetical protein 0.002 0.0073 0.0058
Loa Loa (eye worm) hypothetical protein 0.0066 0.06 0.0903
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0032 0.0021
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0026 0.0146 0.013
Schistosoma mansoni tyrosine kinase 0.0182 0.1914 0.1902
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.022 0.0379
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.2075 0.2528
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0034 0.0019
Brugia malayi TAR-binding protein 0.0386 0.4218 0.6503
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.011 0.0972
Entamoeba histolytica hypothetical protein 0.0058 0.0504 0.0561
Mycobacterium leprae conserved hypothetical protein 0.0087 0.0832 0.208
Loa Loa (eye worm) hypothetical protein 0.0019 0.007 0.0083
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0518 0.5708 0.5701
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0032 0.017
Brugia malayi PHD-finger family protein 0.0024 0.0119 0.0184
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0082 0.0783 0.0768
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0137 0.0084
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0026 0.0146 0.013
Loa Loa (eye worm) hypothetical protein 0.0053 0.0446 0.0664
Echinococcus granulosus peregrin 0.0031 0.0205 0.0189
Schistosoma mansoni aldehyde dehydrogenase 0.0476 0.524 0.5232
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0029 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0203 0.0313
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0073 0.0679 0.1046
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0291 0.0279
Echinococcus multilocularis SAM and MBT domain containing protein 0.0036 0.0263 0.0247
Plasmodium vivax glutathione reductase, putative 0.0032 0.0215 0.1902
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Brugia malayi steroid hormone receptor 0.0031 0.0203 0.0313
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0203 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0476 0.524 0.8548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0783 0.1379
Brugia malayi Bromodomain containing protein 0.0072 0.0661 0.1018
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.06 0.1026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Entamoeba histolytica heat shock transcription factor, putative 0.0115 0.1152 0.14
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Loa Loa (eye worm) hypothetical protein 0.0339 0.3684 0.5668
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0101 0.0086
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.022 0.034
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0026 0.0146 0.0188
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0203 0.0313
Brugia malayi neuropeptide F receptor 0.0016 0.0029 0.0045
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0066 0.06 0.1026
Loa Loa (eye worm) hypothetical protein 0.0019 0.007 0.0083
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0203 0.0187
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0995 1
Onchocerca volvulus 0.0404 0.4425 0.8192
Schistosoma mansoni hypothetical protein 0.0041 0.0319 0.0304
Schistosoma mansoni neuropeptide receptor 0.0016 0.0029 0.0014
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0327 0.0391
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0022 0.0101 0.0156
Loa Loa (eye worm) hypothetical protein 0.0558 0.6162 0.9498
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0016 0.0029 0.0013
Onchocerca volvulus 0.0023 0.0112 0.0179
Echinococcus multilocularis pyruvate kinase 0.0017 0.004 0.0024
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0462 0.0446
Mycobacterium tuberculosis Probable esterase LipL 0.0087 0.0832 0.1313
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0026 0.0146 0.1339
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.018 0.0163
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0203 0.0288
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0022 0.0101 0.0086
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0174 0.1815 0.1802
Schistosoma mansoni inositol monophosphatase 0.0094 0.0909 0.0895
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0026 0.0146 0.0188
Schistosoma mansoni adenoreceptor 0.0016 0.0029 0.0014
Schistosoma mansoni aldehyde dehydrogenase 0.0476 0.524 0.5232
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.005 0.0411 0.0609
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0094 0.0909 0.1711
Brugia malayi PHD-finger family protein 0.0029 0.018 0.0277
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0074 0.0683 0.1069
Plasmodium vivax acetyl-CoA synthetase, putative 0.0019 0.007 0.0398
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.0073 0.0679 0.1024
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0087 0.0832 0.1313
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0026 0.0146 0.0147
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0115 0.1152 0.211
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0029 0.0014
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.002 0.0078 0.0639
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0016 0.0029 0.0045
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0355 0.387 0.5955
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0327 0.0333
Schistosoma mansoni smad 0.002 0.0076 0.0061
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0995 1
Loa Loa (eye worm) glutathione reductase 0.0032 0.0215 0.0307
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0016 0.0029 0.002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0054 0.0462 0.0507
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0462 0.0494
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0016 0.0029 0.0045
Loa Loa (eye worm) melatonin receptor type 1A 0.0016 0.0029 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0029 0.0014
Loa Loa (eye worm) inositol-1 0.0094 0.0909 0.138
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0084 0.0798 0.1987
Loa Loa (eye worm) hypothetical protein 0.005 0.0415 0.0616
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0026 0.0146 0.0147
Brugia malayi G-protein alpha subunit 0.0022 0.0101 0.0156
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0029 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Echinococcus granulosus chromobox protein 1 0.007 0.0638 0.0622
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0203 0.0187
Echinococcus multilocularis lamin dm0 0.01 0.0982 0.0967
Trichomonas vaginalis alpha-glucosidase, putative 0.002 0.0078 0.001
Echinococcus granulosus neuropeptide s receptor 0.0476 0.5231 0.5223
Schistosoma mansoni hypothetical protein 0.0373 0.4067 0.4058
Brugia malayi glutathione reductase 0.0032 0.0215 0.0332
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0029 0.0014
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0022 0.0101 0.0085
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.022 0.2092
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0343 0.334
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.011 0.0151
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0019 0.007 0.0398
Giardia lamblia Alcohol dehydrogenase 0.0026 0.0146 0.0137
Brugia malayi ecdysone receptor 0.0015 0.0016 0.0025
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0101 0.0039
Leishmania major 4-coumarate:coa ligase-like protein 0.0066 0.06 0.112
Schistosoma mansoni myelin transcription factor 1 myt1 0.0042 0.032 0.0305
Schistosoma mansoni neuropeptide receptor 0.0016 0.0029 0.0014
Echinococcus multilocularis microtubule associated protein 2 0.069 0.7653 0.7649
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Schistosoma mansoni acetyl-CoA synthetase 0.0019 0.007 0.0055
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0022 0.0101 0.0086
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0327 0.3183
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0082 0.0783 0.0768
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0137 0.0084
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0172 0.1802 0.1788
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Onchocerca volvulus 0.0255 0.2733 0.5048
Mycobacterium ulcerans lipase LipD 0.0087 0.0832 0.1473
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.038 0.0571
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0203 0.0313
Brugia malayi cytoplasmic intermediate filament protein 0.0054 0.0456 0.0703
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0137 0.0084
Schistosoma mansoni peptidase Clp (S14 family) 0.0082 0.0783 0.0769
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0019 0.007 0.0069
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0108 0.1078 0.1063
Onchocerca volvulus 0.01 0.0982 0.1794
Loa Loa (eye worm) pyruvate kinase 0.0033 0.022 0.0315
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0016 0.0025
Loa Loa (eye worm) TK/INSR protein kinase 0.0108 0.1078 0.164
Leishmania major aldehyde dehydrogenase, putative 0.0026 0.0146 0.0251
Brugia malayi beta-lactamase 0.0087 0.0832 0.1282
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0031
Entamoeba histolytica hypothetical protein 0.0073 0.0679 0.0787
Schistosoma mansoni hypothetical protein 0.0172 0.1802 0.1789
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0611 0.0596
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Loa Loa (eye worm) pyruvate kinase 0.0033 0.022 0.0315
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0203 0.0288
Trypanosoma brucei glycosyl hydrolase-like protein 0.002 0.0078 0.0078
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0518 0.5708 0.5701
Entamoeba histolytica hypothetical protein 0.0073 0.0679 0.0787
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.011 0.0972
Schistosoma mansoni amine GPCR 0.0016 0.0029 0.0014
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0029 0.0014
Brugia malayi Bromodomain containing protein 0.0037 0.0264 0.0407
Echinococcus multilocularis neuropeptide receptor A26 0.0476 0.5231 0.5223
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0638 0.096
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0019 0.007 0.0054
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0019 0.007 0.0054
Schistosoma mansoni hypothetical protein 0.0058 0.0504 0.0489
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0203 0.0288
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0048 0.0396 0.038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0029 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Brugia malayi Protein kinase domain containing protein 0.0108 0.1078 0.1661
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.2075 0.2528
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Echinococcus multilocularis muscleblind protein 0.0558 0.6162 0.6156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0029 0.0014
Onchocerca volvulus 0.012 0.1204 0.2206
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0462 0.0705
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0019 0.007 0.0063
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0016 0.0029 0.0014
Onchocerca volvulus 0.0031 0.0203 0.0346
Loa Loa (eye worm) intermediate filament protein 0.01 0.0982 0.1492
Trichomonas vaginalis glucosylceramidase, putative 0.03 0.3242 0.3998
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0022 0.0101 0.0039
Entamoeba histolytica hypothetical protein 0.0073 0.0679 0.0787
Echinococcus multilocularis expressed conserved protein 0.0094 0.0915 0.09
Echinococcus granulosus dro:myosuppressin receptor 0.0016 0.0029 0.0013
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0016 0.0025
Loa Loa (eye worm) hypothetical protein 0.005 0.0411 0.0609
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0203 0.0313
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.0201
Brugia malayi follicle stimulating hormone receptor 0.0016 0.0029 0.0045
Loa Loa (eye worm) hypothetical protein 0.0078 0.0734 0.1109
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0073 0.0679 0.0831
Onchocerca volvulus 0.0016 0.0029 0.0024
Echinococcus granulosus G protein coupled receptor 139 0.0016 0.0029 0.0013
Echinococcus multilocularis beta LACTamase domain containing family member 0.0087 0.0832 0.0817
Echinococcus granulosus neuropeptide receptor 0.0016 0.0029 0.0013
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0476 0.524 0.5232
Schistosoma mansoni hypothetical protein 0.0897 1 1
Echinococcus granulosus somatostatin receptor 0.0016 0.0029 0.0013
Schistosoma mansoni alpha-glucosidase 0.021 0.2225 0.2213
Trichomonas vaginalis maltase-glucoamylase, putative 0.0054 0.0462 0.0494
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0095
Loa Loa (eye worm) hypothetical protein 0.0087 0.0832 0.126
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0014
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0783 0.1379
Echinococcus multilocularis lysosomal alpha glucosidase 0.0244 0.2609 0.2597
Onchocerca volvulus 0.049 0.5398 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Brugia malayi ecdysteroid receptor 0.0031 0.0203 0.0313
Onchocerca volvulus 0.0016 0.0029 0.0024
Brugia malayi tailless protein 0.0015 0.0016 0.0025
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0026 0.0146 0.0099
Echinococcus granulosus insulin receptor 0.0108 0.1078 0.1063
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0029 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.03 0.3242 0.3998
Echinococcus granulosus orexin receptor type 2 0.0016 0.0029 0.0013
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0016 0.0001
Entamoeba histolytica hypothetical protein 0.0058 0.0504 0.0561
Schistosoma mansoni zinc finger protein 0.0019 0.0061 0.0046
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0029 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0343 0.041
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0203 0.0188
Brugia malayi nuclear receptor RXR 0.0016 0.0036 0.0056
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0203 0.0187
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0074 0.0683 0.1069
Schistosoma mansoni microtubule-associated protein tau 0.069 0.7653 0.7649
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0244 0.2609 0.4007
Brugia malayi intermediate filament protein 0.01 0.0982 0.1514
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0026 0.0146 0.0164
Loa Loa (eye worm) TK/EGFR protein kinase 0.034 0.3692 0.5681
Brugia malayi MH2 domain containing protein 0.0294 0.3172 0.4889
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0327 0.237
Mycobacterium tuberculosis Conserved protein 0.0087 0.0832 0.1313
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Schistosoma mansoni aldehyde dehydrogenase 0.0026 0.0146 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0207 0.2195 0.2679
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.018 0.0163
Schistosoma mansoni hypothetical protein 0.0041 0.0319 0.0304
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0073 0.0679 0.1046
Brugia malayi ORL1-like opioid receptor 0.0016 0.0029 0.0045
Schistosoma mansoni alpha glucosidase 0.0054 0.0462 0.0448
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0203 0.0187
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0016 0.0029 0.0013
Trypanosoma brucei pyruvate kinase 1 0.0033 0.022 0.0257
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0518 0.5708 0.8799
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Schistosoma mansoni hypothetical protein 0.0026 0.0146 0.0131
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0545 0.6019 0.9279
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.004 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0386 0.4218 0.421
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Onchocerca volvulus 0.0141 0.1446 0.2656
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.027 0.0255
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0203 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0291 0.0279
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0702 0.7799 0.9744
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0101 0.0156
Brugia malayi nuclear receptor NHR-88 0.0015 0.0016 0.0025
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0094 0.0909 0.912
Loa Loa (eye worm) MH1 domain-containing protein 0.002 0.0076 0.0092
Onchocerca volvulus 0.0019 0.007 0.01
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0019 0.007 0.0074
Onchocerca volvulus 0.0016 0.0029 0.0024
Toxoplasma gondii hypothetical protein 0.0028 0.0171 0.0268
Schistosoma mansoni tyrosine kinase 0.034 0.3692 0.3682
Loa Loa (eye worm) hypothetical protein 0.0016 0.0036 0.0031
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0111 0.111 0.2032
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0036 0.0263 0.0458
Trypanosoma brucei ceramide phosphorylethanolamine synthase 0.0073 0.0679 0.0831
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0073 0.0679 0.6769
Echinococcus multilocularis mothers against decapentaplegic 5 0.002 0.0076 0.006
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0364 0.0348
Echinococcus granulosus methyl CpG binding domain protein 2 0.0016 0.0034 0.0018
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0026 0.0146 0.1339
Brugia malayi AMP-binding enzyme family protein 0.0019 0.007 0.0108
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0032 0.0049
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0054 0.0456 0.068
Loa Loa (eye worm) hypothetical protein 0.0087 0.0832 0.126
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0022 0.0101 0.0085
Brugia malayi hypothetical protein 0.0015 0.0016 0.0025
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0026 0.0146 0.0147
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.022 0.0189
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0064 0.0579 0.0658
Echinococcus granulosus epidermal growth factor receptor 0.0182 0.1914 0.1901
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0019 0.007 0.0083
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0073 0.0679 0.1046
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0203 0.0346
Schistosoma mansoni intermediate filament proteins 0.01 0.0982 0.0968
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0215 0.2039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0029 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.011 0.0119
Loa Loa (eye worm) hypothetical protein 0.0066 0.06 0.0903
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0026 0.0146 0.0188
Mycobacterium tuberculosis Probable hydrolase 0.0087 0.0832 0.1313
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0783 0.7798
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0016 0.0029 0.0013
Brugia malayi hypothetical protein 0.0016 0.0029 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.022 0.041
Loa Loa (eye worm) hypothetical protein 0.0073 0.0679 0.1024
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0101 0.0086
Schistosoma mansoni lozenge 0.0042 0.0331 0.0316
Schistosoma mansoni tar DNA-binding protein 0.0386 0.4218 0.421
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0203 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0163 0.0116
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0462 0.1069
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0094 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.2075 0.2528
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0073 0.0679 0.0831
Loa Loa (eye worm) hypothetical protein 0.0067 0.0611 0.0919
Brugia malayi Pre-SET motif family protein 0.0051 0.0426 0.0657
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0066 0.06 0.1026
Loa Loa (eye worm) hypothetical protein 0.0078 0.0734 0.1109
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0026 0.0146 0.0147
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0074 0.0683 0.1069
Mycobacterium tuberculosis Probable reductase 0.0074 0.0683 0.1069
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0016 0.0025
Onchocerca volvulus 0.0036 0.0263 0.0458
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0084 0.0798 0.1258
Echinococcus multilocularis inositol monophosphatase 1 0.0094 0.0909 0.0894
Loa Loa (eye worm) hypothetical protein 0.0073 0.0679 0.1024
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.093 0.0915
Onchocerca volvulus 0.0016 0.0029 0.0024
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Toxoplasma gondii thioredoxin reductase 0.0032 0.0215 0.0352
Echinococcus multilocularis pyruvate kinase 0.0017 0.004 0.0024
Plasmodium falciparum acyl-CoA synthetase 0.005 0.0411 0.3931
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0783 0.1443
Leishmania major acetyl-CoA synthetase, putative 0.0019 0.007 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.2075 0.2528
Echinococcus granulosus pyruvate kinase 0.0017 0.004 0.0024
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.002 0.0078 0.0114
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0029 0.0013
Echinococcus multilocularis peregrin 0.0031 0.0205 0.0189
Brugia malayi Tachykinin-like peptides receptor 99D 0.0016 0.0029 0.0045
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0078 0.0734 0.1109
Schistosoma mansoni hypothetical protein 0.023 0.2456 0.2445
Echinococcus multilocularis muscleblind protein 1 0.0558 0.6162 0.6156
Schistosoma mansoni biogenic amine receptor 0.0016 0.0029 0.0014
Plasmodium falciparum phd finger protein, putative 0.0029 0.018 0.1532
Trypanosoma cruzi hypothetical protein, conserved 0.0054 0.0462 0.4559
Entamoeba histolytica hypothetical membrane-spanning protein 0.0073 0.0679 0.0787
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0074 0.0683 0.1673
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.027 0.0391
Echinococcus multilocularis allatostatin A receptor 0.0016 0.0029 0.0013
Schistosoma mansoni aldehyde dehydrogenase 0.0026 0.0146 0.0131
Loa Loa (eye worm) hypothetical protein 0.0082 0.0783 0.1185
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0022 0.0101 0.0085
Brugia malayi hypothetical protein 0.0065 0.0589 0.0909
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0203 0.0188
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.03 0.3242 0.4997
Plasmodium vivax sphingomyelin synthase 2, putative 0.0073 0.0679 0.6713
Mycobacterium ulcerans aldehyde dehydrogenase 0.0476 0.524 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0067 0.0611 0.0595
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.022 0.0257
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0022 0.0101 0.0085
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0273 0.0396
Echinococcus multilocularis thioredoxin glutathione reductase 0.0032 0.0215 0.0199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0029 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0702 0.7799 0.9744
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0026 0.0146 0.0208
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0022 0.0101 0.0156
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0054 0.0462 0.0494
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0029 0.0013
Brugia malayi Serotonin receptor 0.0016 0.0029 0.0045
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0016 0.0001
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0026 0.0146 0.0188
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0203 0.0188
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0022 0.0101 0.0039
Trichomonas vaginalis penicillin-binding protein, putative 0.0087 0.0832 0.096
Entamoeba histolytica G protein alpha subunit, putative 0.0022 0.0101 0.004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0327 0.0497
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0016 0.0029 0.0014
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0087 0.0832 0.1313
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0029 0.0014
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Schistosoma mansoni patched 1 0.0043 0.0337 0.0322
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0026 0.0146 0.0131
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0029 0.0013
Plasmodium vivax pyruvate kinase, putative 0.0033 0.022 0.1955
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0051 0.0426 0.0411
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0094 0.0909 0.1058
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0016 0.0029 0.0024
Schistosoma mansoni inositol monophosphatase 0.0094 0.0909 0.0895
Brugia malayi nuclear hormone receptor 0.0031 0.0203 0.0313
Schistosoma mansoni TGF-beta signal transducer Smad2 0.002 0.0076 0.0061
Brugia malayi MH1 domain containing protein 0.002 0.0076 0.0117
Entamoeba histolytica hypothetical protein 0.0073 0.0679 0.0787
Entamoeba histolytica hypothetical protein 0.0058 0.0504 0.0561
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0048 0.0396 0.038
Loa Loa (eye worm) hypothetical protein 0.0066 0.06 0.0903
Brugia malayi Serotonin receptor 0.0016 0.0029 0.0045
Mycobacterium ulcerans aldehyde dehydrogenase 0.0026 0.0146 0.0147
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0026 0.0146 0.1339
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0022 0.0101 0.0086
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0029 0.0013
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.0995 1
Leishmania major cathepsin L-like protease 0.0044 0.0343 0.0627
Leishmania major trypanothione reductase 0.0032 0.0215 0.0383
Brugia malayi Furin-like cysteine rich region family protein 0.034 0.3692 0.5691
Trichomonas vaginalis esterase, putative 0.0087 0.0832 0.096
Mycobacterium tuberculosis Probable oxidoreductase 0.0082 0.0776 0.1221
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0026 0.0146 0.0251
Echinococcus granulosus GPCR family 2 0.0172 0.1802 0.1788
Echinococcus multilocularis lysosomal alpha glucosidase 0.0244 0.2609 0.2597
Echinococcus multilocularis insulin receptor 0.0108 0.1078 0.1063
Plasmodium vivax hypothetical protein, conserved 0.0087 0.0832 0.8303
Brugia malayi conserved hypotetical protein 0.0015 0.0016 0.0025
Loa Loa (eye worm) beta-lactamase 0.0087 0.0832 0.126
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0029 0.0013
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0203 0.0187
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0022 0.0101 0.0039
Schistosoma mansoni pyruvate kinase 0.0017 0.004 0.0025
Onchocerca volvulus Huntingtin homolog 0.0133 0.135 0.2478
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0172 0.1802 0.2778
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.002
Brugia malayi Aldehyde dehydrogenase protein 4 0.0026 0.0146 0.0226
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0531 0.0795
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0019 0.007 0.0561
Leishmania major cathepsin L-like protease 0.0044 0.0343 0.0627
Onchocerca volvulus Alhambra homolog 0.0029 0.018 0.0303
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0545 0.6019 0.9277
Entamoeba histolytica acyl-CoA synthetase, putative 0.0066 0.06 0.0686
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.093 0.0915
Schistosoma mansoni hypothetical protein 0.0334 0.363 0.362
Echinococcus granulosus muscleblind protein 0.0558 0.6162 0.6156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0029 0.0014
Schistosoma mansoni lamin 0.01 0.0982 0.0968

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) 0.49 uM PUBCHEM_BIOASSAY: Mode of action assay-SAR analysis for compounds that activate KCNQ2 potassium channels on automated patch clamp. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2239, AID2258, AID2287, AID493038] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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