Detailed information for compound 1365106

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 318.371 | Formula: C16H22N4O3
  • H donors: 1 H acceptors: 3 LogP: 2.81 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCNc1c(ccc2=[N+](C3(N=c12)CCCCC3)[O-])[N+](=O)[O-]
  • InChi: 1S/C16H22N4O3/c1-2-3-11-17-14-13(20(22)23)8-7-12-15(14)18-16(19(12)21)9-5-4-6-10-16/h7-8,17H,2-6,9-11H2,1H3
  • InChiKey: RTYCQFJBUAKOHH-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens chromobox homolog 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Onchocerca volvulus Heterochromatin protein 1 homolog Get druggable targets OG5_129545 All targets in OG5_129545
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Brugia malayi Heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Onchocerca volvulus Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Chromobox protein homolog 5, putative Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Brugia malayi Raf kinase 0.0051 0.0062 0.0062
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.003 0.2098
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0086 0.0141 1
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0051 0.0062 0.0062
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.008 0.0126 0.8968
Brugia malayi jmjC domain containing protein 0.0115 0.0205 0.0205
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0068 0.0099 0.0628
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Schistosoma mansoni serine/threonine-protein kinase 0.0086 0.0141 0.0141
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0062 0.0394
Onchocerca volvulus 0.0362 0.075 0.4035
Loa Loa (eye worm) hypothetical protein 0.0852 0.1836 0.1836
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Echinococcus multilocularis calcium dependent secretion activator 1 0.0068 0.0099 0.0119
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0158 0.03 0.03
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0051 0.0062 0.0074
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0132 0.0241 0.0241
Brugia malayi probable spectrin beta chain 0.0068 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Schistosoma mansoni hypothetical protein 0.0068 0.0099 0.0099
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0119 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.3804 0.8371 0.8371
Echinococcus granulosus tyrosine protein kinase csk 0.0051 0.0062 0.0074
Leishmania major serine/threonine-protein kinase a, putative 0.0086 0.0141 1
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0119 0.0119
Schistosoma mansoni protein kinase 0.0051 0.0062 0.0062
Brugia malayi integrin-linked kinase 0.0051 0.0062 0.0062
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.005 0.006 0.006
Schistosoma mansoni regulator of G protein signaling 0.0736 0.1579 0.1579
Schistosoma mansoni hypothetical protein 0.0035 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) sema domain-containing protein 0.0362 0.075 0.075
Loa Loa (eye worm) hypothetical protein 0.0035 0.0028 0.0028
Entamoeba histolytica protein kinase , putative 0.0079 0.0124 0.0782
Giardia lamblia Protein 21.1 0.0051 0.0062 0.0851
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0112 0.7961
Onchocerca volvulus 0.0051 0.0062 0.0255
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0068 0.0099 0.705
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0051 0.0062 0.0062
Loa Loa (eye worm) PXA domain-containing protein 0.0736 0.1579 0.1579
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0051 0.0062 0.0074
Onchocerca volvulus Tyrosine kinase homolog 0.0051 0.0062 0.0255
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0051 0.0062 0.0074
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0068 0.0099 0.0099
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0128
Echinococcus multilocularis semaphorin 5B 0.0362 0.075 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Loa Loa (eye worm) hypothetical protein 0.0736 0.1579 0.1579
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0051 0.0062 0.0074
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Echinococcus multilocularis FL cytokine receptor 0.0051 0.0062 0.0074
Echinococcus granulosus dynamin 1 0.0068 0.0099 0.0119
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Trypanosoma cruzi hypothetical protein 0.0068 0.0099 0.705
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0068 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Entamoeba histolytica hypothetical protein 0.0086 0.0141 0.0891
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0051 0.0062 0.0074
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0062 0.0254
Echinococcus granulosus tyrosine protein kinase shark 0.0051 0.0062 0.0074
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0068 0.0099 0.0628
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Brugia malayi Protein kinase domain containing protein 0.03 0.0614 0.0614
Schistosoma mansoni tyrosine protein kinase 0.0051 0.0062 0.0062
Entamoeba histolytica tyrosin kinase, putative 0.0209 0.0413 0.2615
Onchocerca volvulus 0.0051 0.0062 0.0255
Leishmania major protein kinase, putative 0.0051 0.0062 0.4421
Brugia malayi Sema domain containing protein 0.0362 0.075 0.075
Toxoplasma gondii STE kinase 0.0051 0.0062 0.4421
Loa Loa (eye worm) hypothetical protein 0.0158 0.03 0.03
Schistosoma mansoni growth factor receptor-bound protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) TK/Met protein kinase 0.0051 0.0062 0.0062
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0062 0.0074
Schistosoma mansoni syntrophin 0.0068 0.0099 0.0099
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0051 0.0062 0.0074
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0081 0.0128 0.0153
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Onchocerca volvulus 0.0068 0.0099 0.0459
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.0064
Loa Loa (eye worm) cytohesin 3 0.0068 0.0099 0.0099
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0046 0.0055
Loa Loa (eye worm) AUR protein kinase 0.0079 0.0124 0.0124
Loa Loa (eye worm) TK/RYK protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus mitogen activated protein kinase 0.008 0.0126 0.0151
Schistosoma mansoni serine/threonine-protein kinase 0.0086 0.0141 0.0141
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0086 0.0141 1
Schistosoma mansoni chromobox protein 0.0084 0.0136 0.0136
Echinococcus multilocularis beta adrenergic receptor kinase 0.3481 0.7654 0.9144
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Brugia malayi Sema domain containing protein 0.0362 0.075 0.075
Echinococcus granulosus muscleblind protein 0.018 0.0349 0.0417
Trichomonas vaginalis centaurin/arf, putative 0.0068 0.0099 0.0628
Leishmania major hypothetical protein, conserved 0.0068 0.0099 0.705
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.007 0.0104 0.7371
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Brugia malayi Cadps2 protein 0.0068 0.0099 0.0099
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0086 0.0141 1
Schistosoma mansoni protein kinase 0.0079 0.0124 0.0124
Echinococcus multilocularis neuroglian 0.0081 0.0128 0.0153
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0081 0.0128 0.0128
Schistosoma mansoni serine/threonine RGC 0.0051 0.0062 0.0062
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0068 0.0099 0.0119
Brugia malayi Fibronectin type III domain containing protein 0.0081 0.0128 0.0128
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.003 0.003
Echinococcus granulosus Pleckstrin y 0.0068 0.0099 0.0119
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0028 0.0033
Loa Loa (eye worm) TK/FAK protein kinase 0.0051 0.0062 0.0062
Brugia malayi Bromodomain containing protein 0.0046 0.0052 0.0052
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0062 0.0062
Echinococcus multilocularis Rho GTPase activating protein 24 0.0068 0.0099 0.0119
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0051 0.0062 0.0062
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0051 0.0062 0.0074
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.008 0.0126 0.8968
Echinococcus multilocularis pleckstrin y domain containing family A 0.0068 0.0099 0.0119
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.008 0.0126 0.0126
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0736 0.1579 0.1886
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0051 0.0062 0.0062
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.007 0.0104 0.7371
Echinococcus granulosus defective proboscis extension response 0.0081 0.0128 0.0153
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Plasmodium vivax tyrosine kinase-like protein, putative 0.0051 0.0062 0.4421
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0024 0.0003 0.0004
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Echinococcus granulosus tyrosine protein kinase csk 0.0051 0.0062 0.0074
Schistosoma mansoni centaurin alpha 0.0068 0.0099 0.0099
Brugia malayi Bromodomain containing protein 0.0038 0.0034 0.0034
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0057 0.0075 0.009
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0003 0.0003
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0081 0.0128 0.0153
Echinococcus multilocularis tyrosine protein kinase Blk 0.0051 0.0062 0.0074
Echinococcus multilocularis Pleckstrin y 0.0068 0.0099 0.0119
Brugia malayi Muscleblind-like protein 0.018 0.0349 0.0349
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Echinococcus multilocularis roundabout 2 0.0081 0.0128 0.0153
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0051 0.0062 0.0074
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0205 0.0245
Echinococcus multilocularis tyrosine protein kinase Srms 0.0051 0.0062 0.0074
Toxoplasma gondii AtPH1 family protein 0.0068 0.0099 0.705
Echinococcus multilocularis Immunoglobulin 0.0081 0.0128 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0736 0.1579 1
Schistosoma mansoni fibrocystin l 0.0158 0.03 0.03
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0124 0.0782
Schistosoma mansoni protein kinase 0.0051 0.0062 0.0062
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Schistosoma mansoni protein kinase 0.0051 0.0062 0.0062
Echinococcus granulosus c src tyrosine kinase 0.0051 0.0062 0.0074
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK/ROR protein kinase 0.0051 0.0062 0.0062
Entamoeba histolytica ankyrin repeat protein 0.0051 0.0062 0.0394
Brugia malayi PHD-finger family protein 0.0035 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.0068 0.0099 0.0099
Onchocerca volvulus 0.0068 0.0099 0.0459
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0086 0.0141 1
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0068 0.0099 0.0119
Echinococcus granulosus Oxysterol binding protein 11 0.0068 0.0099 0.0119
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Echinococcus granulosus peregrin 0.0038 0.0034 0.0041
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0086 0.0141 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0 0.5
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.008 0.0126 0.8968
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0051 0.0062 0.0074
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0054 0.0343
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Trypanosoma cruzi NIMA-related kinase, putative 0.0086 0.0141 1
Entamoeba histolytica protein kinase domain containing protein 0.007 0.0104 0.0657
Brugia malayi C-terminal src kinase protein 1 0.0051 0.0062 0.0062
Echinococcus multilocularis myotubularin protein 13 0.0068 0.0099 0.0119
Schistosoma mansoni protein kinase 0.007 0.0104 0.0104
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Echinococcus multilocularis Immunoglobulin 0.0081 0.0128 0.0153
Brugia malayi IPT/TIG domain containing protein 0.0158 0.03 0.03
Echinococcus multilocularis cytohesin 1 0.0068 0.0099 0.0119
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0051 0.0062 0.0074
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.0062 0.0074
Echinococcus granulosus axis inhibition protein axin 0.0736 0.1579 0.1886
Trichomonas vaginalis kinesin light chain, putative 0.0068 0.0099 0.0628
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Entamoeba histolytica hypothetical protein 0.0158 0.03 0.1903
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0051 0.0062 0.0394
Brugia malayi Variant SH3 domain containing protein 0.0068 0.0099 0.0099
Echinococcus granulosus activin receptor type 0.007 0.0104 0.0124
Schistosoma mansoni goodpasture antigen-binding protein 0.0068 0.0099 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0051 0.0062 0.0074
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.0062 0.0062
Brugia malayi Tyrosine-protein kinase PR2 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0068 0.0099 0.0119
Loa Loa (eye worm) SRC-1 0.0051 0.0062 0.0062
Echinococcus granulosus integrin linked protein kinase 0.0051 0.0062 0.0074
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Echinococcus granulosus calcium dependent secretion activator 1 0.0068 0.0099 0.0119
Onchocerca volvulus 0.0051 0.0062 0.0255
Trichomonas vaginalis centaurin beta, putative 0.0068 0.0099 0.0628
Brugia malayi hypothetical protein 0.0736 0.1579 0.1579
Echinococcus granulosus beta-adrenergic receptor kinase 0.3481 0.7654 0.9144
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0136 0.0861
Echinococcus multilocularis DCC interacting protein 13 beta 0.0068 0.0099 0.0119
Onchocerca volvulus 0.0051 0.0062 0.0255
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0068 0.0099 0.0119
Trypanosoma brucei Pseudokinase, putative 0.0051 0.0062 0.4421
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.0331 1
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Entamoeba histolytica cell surface protease gp63, putative 0.0158 0.03 0.1903
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Echinococcus granulosus tyrosine kinase 0.0051 0.0062 0.0074
Plasmodium falciparum phd finger protein, putative 0.0035 0.0028 0.1965
Plasmodium vivax protein kinase, putative 0.0051 0.0062 0.4421
Brugia malayi Guanylyl cyclase protein 23 0.0051 0.0062 0.0062
Trichomonas vaginalis protein transport protein sec7, putative 0.0068 0.0099 0.0628
Echinococcus granulosus cGMP dependent protein kinase 1 0.0024 0.0003 0.0004
Giardia lamblia Aurora kinase 0.0079 0.0124 0.169
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0736 0.1579 1
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0068 0.0099 0.0628
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0068 0.0099 0.0119
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0051 0.0062 0.0074
Onchocerca volvulus 0.0051 0.0062 0.0255
Loa Loa (eye worm) TK/CSK protein kinase 0.0051 0.0062 0.0062
Echinococcus multilocularis hypothetical protein 0.0362 0.075 0.0896
Schistosoma mansoni hypothetical protein 0.049 0.1035 0.1035
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0051 0.0062 0.0074
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0112 0.3381
Toxoplasma gondii aurora kinase 0.0079 0.0124 0.8779
Loa Loa (eye worm) hypothetical protein 0.0736 0.1579 0.1579
Echinococcus multilocularis expressed protein 0.0736 0.1579 0.1886
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0051 0.0062 0.0074
Echinococcus granulosus regulator of G protein signaling 3 0.0736 0.1579 0.1886
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Schistosoma mansoni ephrin receptor 0.0051 0.0062 0.0062
Schistosoma mansoni protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0362 0.075 0.075
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Echinococcus granulosus tyrosine kinase 0.0051 0.0062 0.0074
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.0062 0.0062
Entamoeba histolytica hypothetical protein 0.0736 0.1579 1
Entamoeba histolytica hypothetical protein 0.0068 0.0099 0.0628
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0128
Echinococcus multilocularis regulator of G protein signaling 3 0.0736 0.1579 0.1886
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0141 0.0891
Brugia malayi PH domain containing protein 0.0068 0.0099 0.0099
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0119 0.0119
Loa Loa (eye worm) TK/ALK protein kinase 0.03 0.0613 0.0613
Schistosoma mansoni regulator of G protein signaling 0.0736 0.1579 0.1579
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0051 0.0062 0.4421
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Giardia lamblia Kinase, CMGC MAPK 0.008 0.0126 0.1727
Onchocerca volvulus 0.0068 0.0099 0.0459
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0062 0.0074
Entamoeba histolytica protein kinase, putative 0.0086 0.0141 0.0891
Brugia malayi Tyrosine-protein kinase abl-1 0.0051 0.0062 0.0062
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0051 0.0062 0.0394
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0079 0.0124 0.0782
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Loa Loa (eye worm) RGS-3 protein 0.0736 0.1579 0.1579
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis STE family protein kinase 0.0051 0.0062 0.0394
Brugia malayi Bromodomain containing protein 0.0091 0.015 0.015
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0049 0.0049
Onchocerca volvulus 0.0037 0.0032 0.0087
Echinococcus multilocularis Pleckstrin y 0.0068 0.0099 0.0119
Brugia malayi hypothetical protein 0.0051 0.0062 0.0062
Brugia malayi PXA domain containing protein 0.0736 0.1579 0.1579
Echinococcus granulosus zinc finger protein 0.0024 0.0002 0.0002
Trypanosoma cruzi hypothetical protein 0.0068 0.0099 0.705
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0112 0.0134
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0032
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0081 0.0128 0.0128
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Echinococcus multilocularis regulator of G protein signaling 7 0.0736 0.1579 0.1886
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0119 0.0119
Brugia malayi PH domain containing protein 0.0068 0.0099 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0051 0.0062 0.4421
Echinococcus granulosus cytohesin 1 0.0068 0.0099 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Schistosoma mansoni nephrin 0.0081 0.0128 0.0128
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Trypanosoma cruzi PH domain containing protein, putative 0.0068 0.0099 0.705
Echinococcus multilocularis raf serine:threonine protein kinase 0.0051 0.0062 0.0074
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0025 0.0005 0.0005
Trypanosoma cruzi hypothetical protein 0.0068 0.0099 0.705
Entamoeba histolytica ARF GTPase activating protein, putative 0.0068 0.0099 0.0628
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.005 0.005
Echinococcus granulosus GRB2 associated binding protein 3 0.0068 0.0099 0.0119
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Echinococcus granulosus tyrosine protein kinase Lyn 0.007 0.0104 0.0124
Entamoeba histolytica hypothetical protein 0.0068 0.0099 0.0628
Echinococcus granulosus aurora kinase A 0.0079 0.0124 0.0148
Loa Loa (eye worm) hypothetical protein 0.0736 0.1579 0.1579
Schistosoma mansoni zinc finger protein 0.0068 0.0099 0.0099
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0068 0.0099 0.705
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Echinococcus multilocularis epidermal growth factor receptor 0.0051 0.0062 0.0074
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0051 0.0062 0.0062
Brugia malayi MAP kinase sur-1 0.008 0.0126 0.0126
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0126 0.0799
Entamoeba histolytica hypothetical protein 0.0736 0.1579 1
Brugia malayi Variant SH3 domain containing protein 0.0068 0.0099 0.0099
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0086 0.0141 0.0891
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0068 0.0099 0.0119
Brugia malayi SRC-1 0.0051 0.0062 0.0062
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Loa Loa (eye worm) sema domain-containing protein 0.0362 0.075 0.075
Echinococcus granulosus regulator of G protein signaling 7 0.0736 0.1579 0.1886
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.03 0.1903
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Loa Loa (eye worm) AUR protein kinase 0.0079 0.0124 0.0124
Entamoeba histolytica protein kinase, putative 0.0086 0.0141 0.0891
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0128
Echinococcus granulosus semaphorin 1A 0.0362 0.075 0.0896
Trichomonas vaginalis protein kinase atn1, putative 0.0051 0.0062 0.0394
Echinococcus granulosus roundabout 2 0.0081 0.0128 0.0153
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0058 0.007
Loa Loa (eye worm) PH domain-containing protein 0.0068 0.0099 0.0099
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0086 0.0141 1
Echinococcus multilocularis kinase suppressor of Ras 1 0.0051 0.0062 0.0074
Toxoplasma gondii protein kinase domain-containing protein 0.0086 0.0141 1
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0068 0.0099 0.705
Loa Loa (eye worm) hypothetical protein 0.0158 0.03 0.03
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Loa Loa (eye worm) AGC/AKT protein kinase 0.0086 0.0141 0.0141
Echinococcus granulosus regulator of G protein signaling 3 0.0736 0.1579 0.1886
Echinococcus multilocularis protein KINase family member (kin 25) 0.0051 0.0062 0.0074
Echinococcus multilocularis oxysterol binding protein 9 0.0068 0.0099 0.0119
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0086 0.0141 1
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.03 0.1903
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.008 0.0126 0.8968
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Brugia malayi A-kinase anchor protein 10, precursor 0.0736 0.1579 0.1579
Loa Loa (eye worm) hypothetical protein 0.0085 0.0139 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0051 0.0062 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0736 0.1579 1
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Trichomonas vaginalis centaurin alpha, putative 0.0068 0.0099 0.0628
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0158 0.03 0.03
Entamoeba histolytica hypothetical protein 0.0068 0.0099 0.0628
Loa Loa (eye worm) RNA binding protein 0.0076 0.0119 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0068 0.0099 0.705
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Brugia malayi PXA domain containing protein 0.0736 0.1579 0.1579
Brugia malayi regulator of G-protein signaling rgs-7 0.0736 0.1579 0.1579
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.0331 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0051 0.0062 0.0394
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0141 0.0891
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0041 0.0049
Entamoeba histolytica protein kinase, putative 0.0086 0.0141 0.0891
Toxoplasma gondii hypothetical protein 0.0068 0.0099 0.705
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Toxoplasma gondii hypothetical protein 0.0068 0.0099 0.705
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0062 0.0394
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Loa Loa (eye worm) hypothetical protein 0.0736 0.1579 0.1579
Echinococcus multilocularis axis inhibition protein axin 0.0736 0.1579 0.1886
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0099 0.705
Brugia malayi regulator of G-protein signaling egl-10 0.0736 0.1579 0.1579
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0128
Echinococcus granulosus histone lysine methyltransferase setb 0.0057 0.0075 0.009
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Onchocerca volvulus Putative zinc finger protein 0.0068 0.0099 0.0459
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Brugia malayi Plexin repeat family protein 0.0852 0.1836 0.1836
Echinococcus multilocularis epidermal growth factor receptor 0.0051 0.0062 0.0074
Schistosoma mansoni goodpasture antigen-binding protein 0.0068 0.0099 0.0099
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0205 0.0245
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.001 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0062 0.0062
Onchocerca volvulus 0.0068 0.0099 0.0459
Trichomonas vaginalis alpha chimerin, putative 0.0068 0.0099 0.0628
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Echinococcus granulosus expressed protein 0.0736 0.1579 0.1886
Echinococcus granulosus dual specificity testis-specific protein kinase 0.007 0.0104 0.0124
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0068 0.0099 0.705
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0051 0.0062 0.0062
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Brugia malayi Uncoordinated protein 104 0.0068 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.003 0.0016 0.0016
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Echinococcus multilocularis Ras associated and pleckstrin y 0.0068 0.0099 0.0119
Echinococcus multilocularis tyrosine protein kinase Abl 0.0051 0.0062 0.0074
Schistosoma mansoni myotubularin-related protein 0.0068 0.0099 0.0099
Echinococcus multilocularis protein tyrosine kinase 0.0051 0.0062 0.0074
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0068 0.0099 0.0099
Echinococcus granulosus tyrosine protein kinase Src64B 0.0051 0.0062 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Echinococcus granulosus Rho GTPase activating protein 24 0.0068 0.0099 0.0119
Loa Loa (eye worm) TK/INSR protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK/ABL protein kinase 0.0051 0.0062 0.0062
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Echinococcus multilocularis receptor type guanylyl cyclase 0.0051 0.0062 0.0074
Trypanosoma cruzi PH domain containing protein, putative 0.0068 0.0099 0.705
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0112 0.3381
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0062 0.0394
Echinococcus multilocularis insulin receptor 0.0051 0.0062 0.0074
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Onchocerca volvulus 0.0051 0.0062 0.0255
Echinococcus granulosus epidermal growth factor receptor 0.0051 0.0062 0.0074
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0068 0.0099 0.0628
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0068 0.0099 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Trypanosoma brucei rac serine-threonine kinase, putative 0.0086 0.0141 1
Trypanosoma brucei protein kinase, putative 0.007 0.0104 0.7371
Echinococcus granulosus neuroglian 0.0081 0.0128 0.0153
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0049 0.0059 0.0059
Schistosoma mansoni protein kinase 0.0051 0.0062 0.0062
Echinococcus multilocularis beta 1 syntrophin 0.0068 0.0099 0.0119
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0035 0.0224
Echinococcus granulosus ephrin type A receptor 4 A 0.0051 0.0062 0.0074
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Echinococcus multilocularis Oxysterol binding protein 11 0.0068 0.0099 0.0119
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Schistosoma mansoni oxysterol-binding protein 1 0.0068 0.0099 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0062 0.0393
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0035 0.0224
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.0731 1
Echinococcus granulosus tyrosine protein kinase 0.0051 0.0062 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Schistosoma mansoni hypothetical protein 0.0068 0.0099 0.0099
Trypanosoma cruzi PH domain containing protein, putative 0.0068 0.0099 0.705
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0003 0.0003
Onchocerca volvulus Alhambra homolog 0.0035 0.0028 0.0065
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0158 0.03 0.1903
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Entamoeba histolytica hypothetical protein 0.0068 0.0099 0.0628
Entamoeba histolytica hypothetical protein 0.0736 0.1579 1
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Echinococcus multilocularis GRB2 associated binding protein 3 0.0068 0.0099 0.0119
Entamoeba histolytica PH domain containing protein 0.0068 0.0099 0.0628
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0241 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.03 0.1903
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus Immunoglobulin 0.0081 0.0128 0.0153
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.001 0.001
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0141 0.0891
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0068 0.0099 0.0119
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0736 0.1579 0.1579
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0028 0.0028
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.008 0.0126 0.8968
Echinococcus multilocularis dual specificity testis specific protein kinase 0.007 0.0104 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Echinococcus granulosus retinal guanylyl cyclase 2 0.0051 0.0062 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Echinococcus multilocularis natriuretic peptide receptor 1 0.0051 0.0062 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus exocyst complex component 2 0.0158 0.03 0.0359
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0062 0.0394
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Leishmania major protein kinase, putative 0.007 0.0104 0.7371
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0051 0.0062 0.0074
Echinococcus granulosus retinal guanylyl cyclase 2 0.0051 0.0062 0.0074
Brugia malayi Immunoglobulin I-set domain containing protein 0.0081 0.0128 0.0128
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0003 0.0003
Brugia malayi hypothetical protein 0.0081 0.0128 0.0128
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Leishmania major protein kinase, putative 0.0086 0.0141 1
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0051 0.0062 0.0074
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Entamoeba histolytica PH domain containing protein 0.0068 0.0099 0.0628
Echinococcus multilocularis Pleckstrin y 0.0068 0.0099 0.0119
Entamoeba histolytica tyrosin kinase, putative 0.0051 0.0062 0.0394
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.001 0.0012
Schistosoma mansoni ephrin receptor 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0128
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0051 0.0062 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0068 0.0099 0.0119
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0028 0.1965
Echinococcus multilocularis protein kinase 0.0051 0.0062 0.0074
Echinococcus multilocularis oxysterol binding protein 3 0.0068 0.0099 0.0119
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0062 0.0074
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.3804 0.8371 0.8371
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0062 0.0074
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Schistosoma mansoni cell adhesion molecule 0.0081 0.0128 0.0128
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Brugia malayi Plekhf2 protein 0.0068 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Brugia malayi Dynamin 0.0068 0.0099 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Brugia malayi Pleckstrin Homology Domain 0.0068 0.0099 0.0099
Plasmodium falciparum protein kinase, putative 0.0051 0.0062 0.4421
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Onchocerca volvulus 0.0286 0.0583 0.3116
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0068 0.0099 0.0099
Brugia malayi TAR-binding protein 0.0076 0.0119 0.0119
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0051 0.0062 0.0062
Trypanosoma cruzi protein kinase, putative 0.0051 0.0062 0.4421
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0051 0.0062 0.0074
Echinococcus granulosus tyrosine protein kinase csk 0.0051 0.0062 0.0074
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.1794 0.2144
Leishmania major hypothetical protein, conserved 0.0051 0.0062 0.4421
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.03 0.1903
Echinococcus granulosus activated cdc42 kinase 1 0.0051 0.0062 0.0074
Echinococcus multilocularis MAM 0.003 0.0016 0.0019
Plasmodium falciparum tyrosine kinase-like protein 0.0051 0.0062 0.4421
Giardia lamblia Kinase, NEK 0.0051 0.0062 0.0851
Echinococcus multilocularis G protein coupled receptor kinase 1 0.2744 0.6024 0.7197
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Entamoeba histolytica hypothetical protein 0.0158 0.03 0.1903
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Entamoeba histolytica protein kinase, putative 0.0079 0.0124 0.0782
Loa Loa (eye worm) hypothetical protein 0.0158 0.03 0.03
Echinococcus multilocularis mitogen activated protein kinase 0.008 0.0126 0.0151
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK/EPH protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni protein kinase 0.0051 0.0062 0.0062
Brugia malayi PH domain containing protein 0.0068 0.0099 0.0099
Schistosoma mansoni regulator of G protein signaling 0.0736 0.1579 0.1579
Loa Loa (eye worm) TK/DDR protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Echinococcus granulosus tar DNA binding protein 0.0076 0.0119 0.0142
Echinococcus granulosus activated cdc42 kinase 1 0.0051 0.0062 0.0074
Plasmodium vivax SET domain protein, putative 0.0036 0.003 0.2098
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0736 0.1579 0.1579
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0051 0.0062 0.0074
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0079 0.0124 0.8779
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0736 0.1579 1
Leishmania major protein kinase, putative 0.0024 0.0003 0.0237
Echinococcus multilocularis actin binding protein anillin 0.0068 0.0099 0.0119
Loa Loa (eye worm) AUR protein kinase 0.0079 0.0124 0.0124
Brugia malayi Receptor family ligand binding region containing protein 0.0051 0.0062 0.0062
Entamoeba histolytica hypothetical protein 0.0158 0.03 0.1903
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0079 0.0124 0.0782
Onchocerca volvulus outspread protein homolog 0.0068 0.0099 0.0459
Plasmodium falciparum protein kinase, putative 0.007 0.0104 0.7371
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0128
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0051 0.0062 0.0074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0051 0.0062 0.0394
Brugia malayi Pre-SET motif family protein 0.0036 0.003 0.003
Echinococcus granulosus protein kinase 0.0051 0.0062 0.0074
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0051 0.0062 0.0074
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Trichomonas vaginalis centaurin/arf, putative 0.0068 0.0099 0.0628
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0051 0.0062 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.005 0.005
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trypanosoma brucei PH domain containing protein, putative 0.0068 0.0099 0.705
Loa Loa (eye worm) syntrophin-1 0.0068 0.0099 0.0099
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.0062 0.0062
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0051 0.0062 0.0255
Trypanosoma cruzi Protein kinase B 0.0086 0.0141 1
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.03 0.1903
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0068 0.0099 0.0119
Echinococcus granulosus fibroblast growth factor receptor 4 0.0051 0.0062 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Entamoeba histolytica ankyrin repeat protein 0.0051 0.0062 0.0394
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0362 0.075 0.075
Echinococcus multilocularis tyrosine protein kinase shark 0.0051 0.0062 0.0074
Entamoeba histolytica tyrosin kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0005 0.0005
Onchocerca volvulus Protein melted homolog 0.0068 0.0099 0.0459
Schistosoma mansoni protein kinase 0.007 0.0104 0.0104
Echinococcus multilocularis regulator of G protein signaling 3 0.0736 0.1579 0.1886
Loa Loa (eye worm) hypothetical protein 0.006 0.0083 0.0083
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.007 0.0104 0.7371
Schistosoma mansoni dynamin 0.0068 0.0099 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0051 0.0062 0.4421
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0079 0.0124 0.0148
Leishmania major hypothetical protein, conserved 0.0068 0.0099 0.705
Echinococcus granulosus mitogen activated protein kinase 3 0.008 0.0126 0.0151
Brugia malayi TBC domain containing protein 0.0068 0.0099 0.0099
Echinococcus multilocularis regulator of G protein signaling 0.0736 0.1579 0.1886
Loa Loa (eye worm) hypothetical protein 0.0362 0.075 0.075
Trypanosoma cruzi aurora B kinase, putative 0.0079 0.0124 0.8779
Schistosoma mansoni serine/threonine protein kinase 0.3481 0.7654 0.7654
Trichomonas vaginalis centaurin gamma, putative 0.0068 0.0099 0.0628
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Loa Loa (eye worm) oxysterol binding protein 0.0068 0.0099 0.0099
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0027 0.0032
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0109 0.0131
Echinococcus multilocularis G protein coupled receptor kinase 6 0.3804 0.8371 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus semaphorin 5B 0.0362 0.075 0.0896
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Onchocerca volvulus 0.0051 0.0062 0.0255
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.3804 0.8371 1
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0062 0.0394
Entamoeba histolytica hypothetical protein 0.0086 0.0141 0.0891
Brugia malayi DNA-binding protein LAG-1 0.0158 0.03 0.03
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Leishmania major protein kinase, putative 0.0079 0.0124 0.8779
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0062 0.0074
Brugia malayi Syntrophin-1 0.0068 0.0099 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0362 0.075 0.075
Trypanosoma cruzi hypothetical protein 0.0068 0.0099 0.705
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Brugia malayi bone morphogenetic protein type 1 receptor 0.0051 0.0062 0.0062
Brugia malayi PH domain containing protein 0.0068 0.0099 0.0099
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0028 0.1965
Entamoeba histolytica protein kinase domain containing protein 0.0209 0.0413 0.2615
Schistosoma mansoni regulator of G protein signaling 0.0736 0.1579 0.1579
Brugia malayi protein-tyrosine kinase 0.0051 0.0062 0.0062
Brugia malayi Pre-SET motif family protein 0.0251 0.0506 0.0506
Brugia malayi PH domain containing protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0068 0.0099 0.0119
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0051 0.0062 0.0255
Echinococcus granulosus transcription factor collier 0.0158 0.03 0.0359
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0062 0.0394
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Trichomonas vaginalis protein transport protein sec7, putative 0.0068 0.0099 0.0628
Trypanosoma brucei aurora B kinase 0.0079 0.0124 0.8779
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0068 0.0099 0.0099
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0051 0.0062 0.0074
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0079 0.0124 0.0782
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0068 0.0099 0.0459
Echinococcus granulosus chromobox protein 1 0.0084 0.0136 0.0162
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Echinococcus granulosus twitchin 0.01 0.017 0.0203
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0736 0.1579 0.1579
Echinococcus multilocularis transfer RNA-Thr 0.0051 0.0062 0.0074
Plasmodium falciparum tyrosine kinase-like protein 0.0051 0.0062 0.4421
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0075 0.0075
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0051 0.0062 0.0074
Giardia lamblia Kinase 0.0051 0.0062 0.0851
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0068 0.0099 0.0119
Toxoplasma gondii protein kinase domain-containing protein 0.0051 0.0062 0.4421
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0051 0.0062 0.0074
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0141 0.0891
Echinococcus multilocularis chromobox protein 1 0.0084 0.0136 0.0162
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0051 0.0062 0.0074
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0051 0.0062 0.0074
Brugia malayi hypothetical protein 0.0051 0.0062 0.0062
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Trypanosoma cruzi NIMA-related kinase, putative 0.0086 0.0141 1
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Entamoeba histolytica p21-activated kinase 0.0086 0.0141 0.0891
Echinococcus granulosus axis inhibition protein axin 0.0736 0.1579 0.1886
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Plasmodium falciparum serine/threonine protein kinase, putative 0.0079 0.0124 0.8779
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0051 0.0062 0.0074
Trypanosoma cruzi hypothetical protein 0.0068 0.0099 0.705
Schistosoma mansoni hypothetical protein 0.0158 0.03 0.03
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0041 0.0049
Brugia malayi Oxysterol-binding protein 0.0068 0.0099 0.0099
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0158 0.03 0.1903
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0068 0.0099 0.0628
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Echinococcus granulosus tyrosine kinase 0.0051 0.0062 0.0074
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Trichomonas vaginalis hypothetical protein 0.0068 0.0099 0.0628
Echinococcus granulosus kinase suppressor of Ras 1 0.0051 0.0062 0.0074
Echinococcus granulosus tyrosine protein kinase HCK 0.0051 0.0062 0.0074
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0054 0.0211
Echinococcus granulosus pdz domain containing protein 0.0068 0.0099 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0062 0.0394
Echinococcus multilocularis heat shock protein 70 0.0051 0.0062 0.0074
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Entamoeba histolytica hypothetical protein, conserved 0.0051 0.0062 0.0394
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0062 0.0074
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0058 0.007
Toxoplasma gondii protein kinase 0.0051 0.0062 0.4421
Echinococcus multilocularis tyrosine kinase 0.0051 0.0062 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0112 0.3381
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0051 0.0062 0.0062
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0051 0.0062 0.0062
Brugia malayi hypothetical protein 0.0051 0.0062 0.0062
Schistosoma mansoni protein kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0126 0.0799
Echinococcus multilocularis tyrosine protein kinase pr2 0.0051 0.0062 0.0074
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.1794 0.1794
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0068 0.0099 0.0628
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Brugia malayi hypothetical protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) TK/ACK protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0124 0.0782
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0051 0.0062 0.0394
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0068 0.0099 0.705
Trichomonas vaginalis conserved hypothetical protein 0.0736 0.1579 1
Plasmodium falciparum protein kinase, putative 0.0051 0.0062 0.4421
Entamoeba histolytica protein kinase, putative 0.0086 0.0141 0.0891
Echinococcus multilocularis activated cdc42 kinase 1 0.0051 0.0062 0.0074
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Brugia malayi Probable exocyst complex component Sec5 0.0158 0.03 0.03
Echinococcus multilocularis zinc finger protein 0.0024 0.0002 0.0002
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Echinococcus multilocularis transcription factor collier 0.0158 0.03 0.0359
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Leishmania major folate/biopterin transporter, putative 0.0086 0.0141 1
Toxoplasma gondii Oxysterol-binding protein 0.0068 0.0099 0.705
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0119 0.0142
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0086 0.0141 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0051 0.0062 0.0074
Schistosoma mansoni z-protein (S1r protein) 0.0736 0.1579 0.1579
Entamoeba histolytica cysteine surface protein, putative 0.0051 0.0062 0.0394
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Echinococcus multilocularis tyrosine protein kinase 0.0051 0.0062 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus tyrosine protein kinase Src42A 0.0051 0.0062 0.0074
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0068 0.0099 0.0628
Onchocerca volvulus 0.0051 0.0062 0.0255
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0079 0.0124 0.0148
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Brugia malayi Furin-like cysteine rich region family protein 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Loa Loa (eye worm) uncoordinated protein 104 0.0068 0.0099 0.0099
Echinococcus multilocularis oxysterol binding protein 1 0.0068 0.0099 0.0119
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Onchocerca volvulus 0.0051 0.0062 0.0255
Echinococcus granulosus Pleckstrin y 0.0068 0.0099 0.0119
Plasmodium falciparum cGMP-dependent protein kinase 0.0024 0.0003 0.0237
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0051 0.0062 0.0074
Echinococcus multilocularis muscleblind protein 0.018 0.0349 0.0417
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.0331 0.5
Echinococcus multilocularis peregrin 0.0038 0.0034 0.0041
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.03 0.1903
Trichomonas vaginalis conserved hypothetical protein 0.0736 0.1579 1
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.03 0.1903
Loa Loa (eye worm) hypothetical protein 0.0046 0.0052 0.0052
Echinococcus multilocularis exocyst complex component 2 0.0158 0.03 0.0359
Brugia malayi SH2 domain containing protein 0.0051 0.0062 0.0062
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0086 0.0141 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) TK protein kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0051 0.0062 0.0074
Echinococcus granulosus tyrosine protein kinase pr2 0.0051 0.0062 0.0074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Echinococcus granulosus insulin receptor 0.0051 0.0062 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0054 0.0343
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0068 0.0099 0.0119
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Brugia malayi PH domain containing protein 0.0068 0.0099 0.0099
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0158 0.03 0.1903
Schistosoma mansoni axis inhibition protein axin 0.0736 0.1579 0.1579
Brugia malayi jmjC domain containing protein 0.0045 0.0049 0.0049
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0051 0.0062 0.0074
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0119 0.0119
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0068 0.0099 0.705
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0362 0.075 0.075
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0086 0.0141 1
Trypanosoma cruzi hypothetical protein 0.0068 0.0099 0.705
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Echinococcus granulosus G protein coupled receptor kinase 1 0.2744 0.6024 0.7197
Echinococcus granulosus microtubule associated protein 2 0.0833 0.1794 0.2144
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0086 0.0141 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.0731 1
Echinococcus multilocularis muscleblind protein 1 0.018 0.0349 0.0417
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0736 0.1579 0.1579
Echinococcus granulosus protein tyrosine kinase 0.0051 0.0062 0.0074
Trypanosoma cruzi PH domain containing protein, putative 0.0068 0.0099 0.705
Brugia malayi Regulator of G protein signaling domain containing protein 0.0736 0.1579 0.1579
Echinococcus granulosus beta 1 syntrophin 0.0068 0.0099 0.0119
Schistosoma mansoni bromodomain containing protein 0.0076 0.0119 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.007 0.0104 0.7371
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Entamoeba histolytica receptor protein kinase, putative 0.0051 0.0062 0.0394
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.003 0.0016 0.0016
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0112 0.7961
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus multilocularis pdz domain containing protein 0.0068 0.0099 0.0119
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0024 0.0003 0.0237
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Brugia malayi serine/threonine-protein kinase 6 0.0079 0.0124 0.0124
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0068 0.0099 0.0459
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0109 0.0131
Schistosoma mansoni chromobox protein 0.0084 0.0136 0.0136
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0158 0.03 0.1903
Echinococcus granulosus oxysterol binding protein 9 0.0068 0.0099 0.0119
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0024 0.015
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0141 0.0891
Trypanosoma cruzi protein kinase, putative 0.0051 0.0062 0.4421
Brugia malayi PHD-finger family protein 0.003 0.0016 0.0016
Echinococcus granulosus tyrosine protein kinase ABL1 0.0051 0.0062 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Plasmodium vivax PH domain containing protein 0.0068 0.0099 0.705
Schistosoma mansoni plexin 0.0852 0.1836 0.1836
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0362 0.075 0.075
Loa Loa (eye worm) hypothetical protein 0.003 0.0016 0.0016
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.0062 0.0074
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0028 0.0033
Trichomonas vaginalis TK family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0062 0.0394
Entamoeba histolytica protein kinase, putative 0.0086 0.0141 0.0891
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0051 0.0062 0.0074
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Echinococcus granulosus chromobox protein 1 0.0084 0.0136 0.0162
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Giardia lamblia PHD finger protein 15 0.0035 0.0028 0.0378
Brugia malayi hypothetical protein 0.0362 0.075 0.075
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0051 0.0062 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Schistosoma mansoni plexin 0.049 0.1035 0.1035
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Echinococcus multilocularis tyrosine kinase 0.0051 0.0062 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus tyrosine protein kinase Srms 0.0051 0.0062 0.0074
Schistosoma mansoni hypothetical protein 0.003 0.0016 0.0016
Schistosoma mansoni semaphorin 5-related 0.0362 0.075 0.075
Schistosoma mansoni vesicular amine transporter 0.0083 0.0134 0.0134
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0046 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0062 0.0394
Onchocerca volvulus 0.0051 0.0062 0.0255
Echinococcus granulosus serine/threonine protein kinase 0.0086 0.0141 0.0168
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Echinococcus granulosus cGMP dependent protein kinase 1 0.0024 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Brugia malayi serine/threonine protein kinase 6 0.0079 0.0124 0.0124
Echinococcus multilocularis protein kinase 0.0051 0.0062 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Plasmodium falciparum PH domain-containing protein, putative 0.0068 0.0099 0.705
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0086 0.0141 0.0891
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0062 0.0394
Loa Loa (eye worm) plexin A 0.1011 0.2187 0.2187
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0111 0.0111
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0051 0.0062 0.0394
Echinococcus multilocularis rac serine:threonine kinase 0.0086 0.0141 0.0168
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.0062 0.0074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.0062 0.0394
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Trypanosoma brucei protein kinase, putative 0.008 0.0126 0.8968
Loa Loa (eye worm) hypothetical protein 0.049 0.1035 0.1035
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0086 0.0141 1
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0051 0.0062 0.0074
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0158 0.03 0.1903
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0119 0.0119
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0068 0.0099 0.0628
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0028 0.0028
Echinococcus multilocularis ephrin type A receptor 4 A 0.0051 0.0062 0.0074
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Echinococcus granulosus Regulator of G protein signaling 20 0.0736 0.1579 0.1886
Brugia malayi plexin A 0.1011 0.2187 0.2187
Schistosoma mansoni rho gtpase activating protein 0.0068 0.0099 0.0099
Echinococcus granulosus receptor type guanylyl cyclase 0.0051 0.0062 0.0074
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0124 0.0782
Trichomonas vaginalis conserved hypothetical protein 0.0736 0.1579 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.008 0.0126 0.8968
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0126 0.0799
Onchocerca volvulus 0.0852 0.1836 1
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Brugia malayi ephrin receptor 1 precursor 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Brugia malayi PH domain containing protein 0.0068 0.0099 0.0099
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus multilocularis tyrosine protein kinase HCK 0.0051 0.0062 0.0074
Echinococcus multilocularis mitogen activated protein kinase 3 0.008 0.0126 0.0151
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0051 0.0062 0.0074
Onchocerca volvulus 0.0051 0.0062 0.0255
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Echinococcus multilocularis aurora kinase A 0.0079 0.0124 0.0148
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0086 0.0141 1
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0126 0.0799
Echinococcus granulosus raf serine:threonine protein kinase 0.0051 0.0062 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus multilocularis Regulator of G protein signaling 20 0.0736 0.1579 0.1886
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Brugia malayi hypothetical protein 0.003 0.0016 0.0016
Entamoeba histolytica tyrosin kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0128
Brugia malayi Egg laying defective protein 4 0.0024 0.0003 0.0003
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) protein kinase domain-containing protein 0.0051 0.0062 0.0062
Giardia lamblia Kinase, NEK 0.0051 0.0062 0.0851
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Echinococcus granulosus oxysterol binding protein 3 0.0068 0.0099 0.0119
Onchocerca volvulus 0.0051 0.0062 0.0255
Schistosoma mansoni dynamin 0.0068 0.0099 0.0099
Brugia malayi SH2 domain containing protein 0.0051 0.0062 0.0062
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0049 0.0049
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Entamoeba histolytica protein kinase, putative 0.0086 0.0141 0.0891
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0112 0.0112
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0068 0.0099 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Onchocerca volvulus 0.0068 0.0099 0.0459
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.4541 1 1
Echinococcus granulosus tyrosine protein kinase Blk 0.0051 0.0062 0.0074
Entamoeba histolytica PH domain containing protein 0.0068 0.0099 0.0628
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Leishmania major protein kinase, putative 0.0024 0.0003 0.0237
Loa Loa (eye worm) hypothetical protein 0.018 0.0349 0.0349
Echinococcus granulosus plexin a4 0.1011 0.2187 0.2612
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0068 0.0099 0.0099
Brugia malayi Protein kinase domain containing protein 0.0086 0.0141 0.0141
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Entamoeba histolytica receptor protein kinase, putative 0.0051 0.0062 0.0394
Echinococcus granulosus MAM 0.003 0.0016 0.0019
Schistosoma mansoni protein kinase 0.007 0.0104 0.0104
Brugia malayi PH domain containing protein 0.0068 0.0099 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0124 0.0782
Schistosoma mansoni vav2 0.0068 0.0099 0.0099
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0051 0.0062 0.0074
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0028 0.1965
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Plasmodium falciparum oxysterol-binding protein, putative 0.0068 0.0099 0.705
Onchocerca volvulus 0.005 0.006 0.0243
Echinococcus multilocularis axis inhibition protein axin 0.0736 0.1579 0.1886
Entamoeba histolytica protein kinase, putative 0.0086 0.0141 0.0891
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) hypothetical protein 0.0736 0.1579 0.1579
Entamoeba histolytica protein kinase, putative 0.0079 0.0124 0.0782
Loa Loa (eye worm) hypothetical protein 0.003 0.0016 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0086 0.0141 0.0891
Loa Loa (eye worm) rho-GTPase-activating 0.0068 0.0099 0.0099
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Brugia malayi Regulator of G protein signaling domain containing protein 0.0736 0.1579 0.1579
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0153 0.0153
Entamoeba histolytica hypothetical protein 0.0158 0.03 0.1903
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0068 0.0099 0.705
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Brugia malayi RNA binding protein 0.0076 0.0119 0.0119
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0051 0.0062 0.0074
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0075 0.0075
Plasmodium vivax tyrosine kinase-like protein, putative 0.0051 0.0062 0.4421
Echinococcus granulosus Pleckstrin y 0.0068 0.0099 0.0119
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0041 0.0041
Onchocerca volvulus 0.0068 0.0099 0.0459
Echinococcus granulosus DCC interacting protein 13 beta 0.0068 0.0099 0.0119
Loa Loa (eye worm) TK/EGFR protein kinase 0.0051 0.0062 0.0062
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Brugia malayi Cytohesin 3 0.0068 0.0099 0.0099
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.0731 0.4629
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus granulosus pleckstrin y domain containing family A 0.0068 0.0099 0.0119
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0128
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0068 0.0099 0.0628
Echinococcus multilocularis c src tyrosine kinase 0.0051 0.0062 0.0074
Brugia malayi MAX-1A 0.0068 0.0099 0.0099
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.008 0.0126 0.8968
Echinococcus granulosus oxysterol binding protein 1 0.0068 0.0099 0.0119
Schistosoma mansoni regulator of G protein signaling 0.0736 0.1579 0.1579
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0068 0.0099 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus multilocularis chromobox protein 1 0.0084 0.0136 0.0162
Onchocerca volvulus 0.0051 0.0062 0.0255
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0024 0.015
Trypanosoma brucei protein kinase, putative 0.0086 0.0141 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0051 0.0062 0.0062
Brugia malayi Oxysterol binding protein 0.0068 0.0099 0.0099
Echinococcus multilocularis plexin a4 0.1011 0.2187 0.2612
Echinococcus multilocularis integrin linked protein kinase 0.0051 0.0062 0.0074
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0736 0.1579 0.1579
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0062 0.0393
Loa Loa (eye worm) hypothetical protein 0.0051 0.0062 0.0062
Trypanosoma cruzi hypothetical protein 0.0068 0.0099 0.705
Schistosoma mansoni serine/threonine protein kinase 0.3481 0.7654 0.7654
Loa Loa (eye worm) hypothetical protein 0.0036 0.0029 0.0029
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0086 0.0141 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0119 0.0119
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0086 0.0141 1
Trichomonas vaginalis set domain proteins, putative 0.0286 0.0583 0.3691
Echinococcus granulosus myotubularin protein 13 0.0068 0.0099 0.0119
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.0062 0.0074
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.3481 0.7654 0.7654
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0062 0.0062
Toxoplasma gondii phosphatidylinositol transfer protein 0.0068 0.0099 0.705
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Plasmodium falciparum calcium-dependent protein kinase 7 0.0086 0.0141 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0086 0.0141 0.0891
Loa Loa (eye worm) hypothetical protein 0.0047 0.0054 0.0054
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.003 0.0035
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0044 0.0053
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.4541 1 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0128
Onchocerca volvulus 0.0051 0.0062 0.0255
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Schistosoma mansoni zinc finger protein 0.0068 0.0099 0.0099
Brugia malayi PH domain containing protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0219 0.0435 0.0435
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0068 0.0099 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.0062 0.0074
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0051 0.0062 0.0394
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0086 0.0141 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0024 0.0003 0.0004
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.018 0.0349 0.0349
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0051 0.0062 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0062 0.0394
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0068 0.0099 0.0099
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0068 0.0099 0.0628
Leishmania major protein kinase, putative 0.0086 0.0141 1
Schistosoma mansoni hypothetical protein 0.0051 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0068 0.0099 0.0099
Brugia malayi Dynamin 0.0068 0.0099 0.0099
Echinococcus multilocularis expressed conserved protein 0.0024 0.0003 0.0004
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Trypanosoma brucei Flagellum attachment zone protein 20 0.0051 0.0062 0.4421
Echinococcus granulosus regulator of G protein signaling 7 0.0736 0.1579 0.1886
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0051 0.0062 0.0062
Entamoeba histolytica hypothetical protein 0.0068 0.0099 0.0628
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.0506 0.0506
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0136 0.0861
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.0062 0.0394
Schistosoma mansoni hypothetical protein 0.0362 0.075 0.075
Loa Loa (eye worm) hypothetical protein 0.0057 0.0075 0.0075
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0062 0.0394
Echinococcus granulosus natriuretic peptide receptor 1 0.0051 0.0062 0.0074
Loa Loa (eye worm) hypothetical protein 0.0362 0.075 0.075
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0041 0.0041
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0051 0.0062 0.0062
Echinococcus granulosus cGMP dependent protein kinase 0.0024 0.0003 0.0004
Onchocerca volvulus 0.0068 0.0099 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0124 0.0124
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0051 0.0062 0.0074
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0051 0.0062 0.0062
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.3804 0.8371 0.8371
Schistosoma mansoni axis inhibition protein axin 0.0736 0.1579 0.1579
Schistosoma mansoni zinc finger protein 0.0024 0.0002 0.0002
Brugia malayi chromobox protein homolog 3 0.0047 0.0054 0.0054
Schistosoma mansoni protein kinase 0.0051 0.0062 0.0062
Brugia malayi Heterochromatin protein 1 0.0084 0.0136 0.0136
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0051 0.0062 0.0062
Schistosoma mansoni protein tyrosine kinase 0.0051 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) AGC/PKG protein kinase 0.0024 0.0003 0.0003
Loa Loa (eye worm) Plekhf2 protein 0.0068 0.0099 0.0099
Echinococcus multilocularis activin receptor type 0.007 0.0104 0.0124
Schistosoma mansoni oxysterol-binding protein 1 0.0068 0.0099 0.0099
Echinococcus granulosus epidermal growth factor receptor 0.0051 0.0062 0.0074
Entamoeba histolytica hypothetical protein 0.0051 0.0062 0.0394
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0112 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0099 0.0628
Trichomonas vaginalis TKL family protein kinase 0.0051 0.0062 0.0394
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0049 0.0049
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0049 0.0059
Schistosoma mansoni hypothetical protein 0.0068 0.0099 0.0099
Onchocerca volvulus 0.0051 0.0062 0.0255
Brugia malayi Protein kinase domain containing protein 0.0051 0.0062 0.0062
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0112 0.3381
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0068 0.0099 0.0628
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0086 0.0141 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.008 0.0126 0.8968
Brugia malayi hypothetical protein 0.0362 0.075 0.075
Echinococcus multilocularis regulator of G protein signaling 7 0.0736 0.1579 0.1886
Trichomonas vaginalis protein tyrosine kinase, putative 0.0051 0.0062 0.0394
Entamoeba histolytica protein kinase, putative 0.0051 0.0062 0.0394
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0068 0.0099 0.0119
Echinococcus granulosus retinal guanylyl cyclase 2 0.0051 0.0062 0.0074
Entamoeba histolytica hypothetical protein, conserved 0.0068 0.0099 0.0628
Brugia malayi hypothetical protein 0.0736 0.1579 0.1579
Trichomonas vaginalis AGC family protein kinase 0.0079 0.0124 0.0782
Brugia malayi serine/threonine kinase 12 0.0079 0.0124 0.0124
Echinococcus multilocularis dynamin 1 0.0068 0.0099 0.0119
Schistosoma mansoni tyrosine kinase 0.0051 0.0062 0.0062
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0068 0.0099 0.705
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.0062 0.0394
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0068 0.0099 0.0099
Loa Loa (eye worm) serine/threonine protein kinase 0.0051 0.0062 0.0062
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0068 0.0099 0.0628
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0112 0.0112
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0736 0.1579 0.1886

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) 43.791 uM PUBCHEM_BIOASSAY: Discovery of Small Molecule Probes for H1N1 Influenza NS1A. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504399] ChEMBL. No reference
Potency (functional) 0.01 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.4125 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (binding) 1.5849 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.7783 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF. (Class of assay: confirmatory) [Related pubchem assays: 995 ] ChEMBL. No reference
Potency (functional) 2.2387 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 4.4563 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) 5.0119 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (binding) = 8.9125 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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