Detailed information for compound 1374934

Basic information

Technical information
  • TDR Targets ID: 1374934
  • Name: 3-(4-methoxyphenyl)-N-methyl-N-(phenylmethyl) -4,5-dihydro-1,2-oxazole-5-carboxamide
  • MW: 324.374 | Formula: C19H20N2O3
  • H donors: 0 H acceptors: 1 LogP: 2.81 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C1=NOC(C1)C(=O)N(Cc1ccccc1)C
  • InChi: 1S/C19H20N2O3/c1-21(13-14-6-4-3-5-7-14)19(22)18-12-17(20-24-18)15-8-10-16(23-2)11-9-15/h3-11,18H,12-13H2,1-2H3
  • InChiKey: LZFBWKVPXLHZPZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(4-methoxyphenyl)-N-methyl-N-(phenylmethyl)-4,5-dihydroisoxazole-5-carboxamide
  • N-(benzyl)-3-(4-methoxyphenyl)-N-methyl-4,5-dihydroisoxazole-5-carboxamide
  • MLS000731406
  • N-benzyl-3-(4-methoxyphenyl)-N-methyl-4,5-dihydroisoxazole-5-carboxamide
  • SMR000309681
  • ChemDiv3_010532

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus lysine specific demethylase 5A 0.005 0.0076 0.0075
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0008 0.0008
Schistosoma mansoni lamin 0.0057 0.009 0.009
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0126
Toxoplasma gondii transporter, cation channel family protein 0.0045 0.0066 0.0372
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0137 0.0819
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0015 0.0015
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0071 0.0296
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.007 0.007
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0071 0.0295
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Brugia malayi Pre-SET motif family protein 0.0234 0.0451 0.0451
Schistosoma mansoni jumonji/arid domain-containing protein 0.005 0.0076 0.0076
Echinococcus multilocularis Niemann Pick C1 protein 0.0205 0.0392 0.0392
Echinococcus multilocularis orexin receptor type 2 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0834 0.1676 0.1675
Echinococcus multilocularis voltage dependent calcium channel 0.0045 0.0066 0.0066
Brugia malayi phosphofructokinase 0.0116 0.0211 0.0211
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0084 0.0084
Toxoplasma gondii hypothetical protein 0.0037 0.005 0.0279
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0049 0.0924
Echinococcus granulosus neuropeptide s receptor 0.0496 0.0987 0.0987
Mycobacterium ulcerans epimerase 0.0021 0.0017 0.0402
Mycobacterium leprae Conserved hypothetical protein 0.0019 0.0012 0.0519
Schistosoma mansoni intermediate filament proteins 0.0057 0.009 0.009
Echinococcus granulosus g-protein coupled receptor 0.0017 0.0008 0.0008
Brugia malayi TAR-binding protein 0.0064 0.0105 0.0105
Brugia malayi beta-lactamase 0.004 0.0056 0.0056
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0017 0.0008 0.0008
Echinococcus multilocularis expressed conserved protein 0.0192 0.0367 0.0366
Echinococcus granulosus peregrin 0.0038 0.0051 0.0051
Onchocerca volvulus 0.0017 0.0008 0.0007
Trypanosoma brucei ISWI complex protein 0.0015 0.0006 0.0009
Echinococcus multilocularis serotonin receptor 0.0017 0.0008 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0075 0.0312
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0017 0.0008 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0221 0.0221
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0045 0.0841
Schistosoma mansoni histamine h1 receptor 0.0017 0.0008 0.0008
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0004 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0075 0.2139
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0084 0.162
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0075 0.1908
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0015 0.0015
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0074 0.0074
Onchocerca volvulus 0.0834 0.1676 0.1675
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0124 0.0228 0.0228
Trichomonas vaginalis esterase, putative 0.004 0.0056 0.1082
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0047 0.0917
Loa Loa (eye worm) hypothetical protein 0.0049 0.0075 0.0075
Mycobacterium ulcerans 6-phosphofructokinase 0.0116 0.0211 0.6235
Mycobacterium tuberculosis Conserved hypothetical protein 0.0177 0.0336 0.6731
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0108 0.0108
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.007 0.007
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0012 0.0173
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0834 0.1676 0.1676
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0084 0.0479
Brugia malayi putative neuropeptide receptor NPR1 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0056 0.106
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0015 0.0015
Echinococcus granulosus zinc finger protein 0.0025 0.0025 0.0025
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.0004 0.0111
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0105 0.0105
Brugia malayi Pre-SET motif family protein 0.0035 0.0046 0.0046
Schistosoma mansoni polycystin 1-related 0.0021 0.0017 0.0017
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0015 0.0015
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0106 0.019 0.019
Brugia malayi hypothetical protein 0.0021 0.0017 0.0016
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0008 0.0008
Echinococcus granulosus dnaJ subfamily B 0.1295 0.2615 0.2615
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0026 0.0509
Loa Loa (eye worm) RecQ helicase 0.0022 0.002 0.0019
Echinococcus granulosus tm gpcr rhodopsin 0.0556 0.1109 0.1109
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0044 0.0063 0.0063
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0084 0.0351
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0017 0.0271
Onchocerca volvulus 0.0266 0.0517 0.0516
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0015 0.0014
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0038 0.0206
Schistosoma mansoni hypothetical protein 0.0017 0.0008 0.0008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) cytochrome P450 0.0019 0.0012 0.0012
Echinococcus granulosus geminin 0.0205 0.0392 0.0392
Schistosoma mansoni amine GPCR 0.0017 0.0008 0.0008
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0004 0.0004
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0056 0.106
Brugia malayi Cytochrome P450 family protein 0.0028 0.0031 0.0031
Onchocerca volvulus 0.0017 0.0008 0.0007
Brugia malayi Cytochrome P450 family protein 0.0059 0.0094 0.0094
Brugia malayi neuropeptide F receptor 0.0017 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0033 0.0042 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0834 0.1676 0.1676
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0054 0.1504
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0013 0.0056
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0075 0.3503
Schistosoma mansoni cpg binding protein 0.0091 0.016 0.016
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.0012 0.0257
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Echinococcus multilocularis transcription factor Dp 1 0.008 0.0138 0.0138
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0035 0.0046 0.0046
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0016 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0105 0.0188 0.0188
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0056 0.1082
Echinococcus multilocularis g-protein coupled receptor 0.0017 0.0008 0.0008
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0087 0.0087
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0045 0.0066 0.0066
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0015 0.0015
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.0012 0.0257
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0153 0.0153
Echinococcus multilocularis zinc finger protein 0.0025 0.0025 0.0025
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.0012 0.0257
Schistosoma mansoni hypothetical protein 0.0085 0.0147 0.0147
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.004 0.0781
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0081 0.0081
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0051 0.0212
Onchocerca volvulus 0.0038 0.0052 0.005
Leishmania major C-8 sterol isomerase-like protein 0.1165 0.2352 1
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0084 0.0084
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0004 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0075 0.2139
Schistosoma mansoni growth hormone secretagogue receptor 0.0017 0.0008 0.0008
Brugia malayi Cytochrome P450 family protein 0.0028 0.0031 0.0031
Loa Loa (eye worm) solute carrier family 6 member 4 0.4914 1 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0007 0.0006
Onchocerca volvulus 0.0014 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0012 0.0173
Echinococcus multilocularis bloom syndrome protein 0.0022 0.002 0.0019
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0834 0.1676 1
Brugia malayi hypothetical protein 0.0017 0.0009 0.0009
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0834 0.1676 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0017 0.0008 0.0008
Echinococcus multilocularis neuropeptide s receptor 0.0496 0.0987 0.0987
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0105 0.3045
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0045 0.0066 0.0066
Treponema pallidum sodium- and chloride- dependent transporter 0.4914 1 1
Mycobacterium tuberculosis Conserved protein 0.004 0.0056 0.106
Leishmania major cytochrome p450-like protein 0.0019 0.0012 0.0046
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0735
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Schistosoma mansoni survival motor neuron protein 0.0101 0.0181 0.0181
Echinococcus granulosus bloom syndrome protein 0.0022 0.002 0.0019
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0007 0.0006
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0005 0.0005
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0015 0.0015
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0019 0.0013 0.0013
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.0211 0.0211
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0046 0.0253
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0054 0.0222
Loa Loa (eye worm) CHromoDomain protein family member 0.0019 0.0013 0.0013
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0108 0.0108
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0834 0.1676 0.1676
Schistosoma mansoni rab6-interacting 0.0021 0.0017 0.0017
Chlamydia trachomatis endonuclease IV 0.008 0.0137 0.0811
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0084 0.0351
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0015 0.0015
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0094 0.0165 0.0165
Brugia malayi follicle stimulating hormone receptor 0.0259 0.0503 0.0503
Echinococcus multilocularis 0.0019 0.0012 0.0012
Brugia malayi Doublecortin family protein 0.0021 0.0017 0.0016
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0138 0.0257 0.1086
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0735
Echinococcus multilocularis RUN 0.0021 0.0017 0.0016
Onchocerca volvulus 0.0017 0.0008 0.0007
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0012 0.0173
Loa Loa (eye worm) hypothetical protein 0.0106 0.019 0.019
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.4914 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.0092 0.009
Schistosoma mansoni hypothetical protein 0.0017 0.0008 0.0008
Echinococcus granulosus voltage dependent calcium channel 0.0045 0.0066 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0015 0.0015
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0337 0.0661 0.2806
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0209 0.0209
Schistosoma mansoni sodium/chloride dependent transporter 0.4914 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0008 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0015 0.0015
Echinococcus granulosus tumor protein p63 0.0717 0.1437 0.1437
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0018 0.0344
Loa Loa (eye worm) hypothetical protein 0.4914 1 1
Echinococcus granulosus neuropeptide receptor A26 0.0496 0.0987 0.0987
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0081 0.0081
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.0211 0.538
Schistosoma mansoni thyroid hormone receptor 0.002 0.0015 0.0015
Echinococcus multilocularis voltage gated potassium channel 0.0016 0.0007 0.0007
Schistosoma mansoni neuropeptide f receptor 76f 0.0017 0.0008 0.0008
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0071 0.1809
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0019 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0071 0.137
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0023 0.0023
Loa Loa (eye worm) norepinephrine transporter 0.4914 1 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0153 0.0153
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0092 0.0092
Echinococcus multilocularis G protein coupled receptor 139 0.0017 0.0008 0.0008
Brugia malayi G-protein coupled receptor 0.0017 0.0008 0.0008
Echinococcus granulosus g protein coupled receptor 0.0017 0.0008 0.0008
Trypanosoma brucei protein kinase, putative 0.0054 0.0084 0.0341
Brugia malayi Niemann-Pick C1 protein precursor 0.0205 0.0392 0.0392
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0004 0.0004
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0008 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0211 0.4078
Onchocerca volvulus 0.4914 1 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0038 0.0735
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0045 0.0066 0.0066
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0017 0.0008 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0075 0.2139
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0008 0.0008
Toxoplasma gondii hypothetical protein 0.0834 0.1676 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.0012 0.0257
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0084 0.0351
Brugia malayi Dopamine receptor 0.0017 0.0008 0.0008
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0004 0.001
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0015 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0075 0.0075
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0017 0.0008 0.0008
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0004 0.001
Echinococcus granulosus neuropeptide receptor 0.0017 0.0008 0.0008
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0017 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0007 0.0007
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0038 0.0219
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0084 0.162
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0004 0.001
Schistosoma mansoni biogenic amine receptor 0.0017 0.0008 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0008 0.0008
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0008 0.0008
Brugia malayi hypothetical protein 0.0043 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0048 0.0073 0.0073
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0013 0.0013
Echinococcus granulosus peptide allatostatin:somatostatin 0.0017 0.0008 0.0008
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0015 0.0015
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.0063 0.0063
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0038 0.0219
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0008 0.0008
Echinococcus granulosus tachykinin peptides receptor 99D 0.0017 0.0008 0.0008
Mycobacterium leprae conserved hypothetical protein 0.004 0.0056 0.2609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0046 0.089
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0054 0.0054
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.002 0.0376
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0013 0.0056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0015 0.0015
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0017 0.0017
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.008 0.0137 0.6487
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.0012 0.0257
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0092 0.0092
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0084 0.0084
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Schistosoma mansoni lozenge 0.0059 0.0094 0.0094
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0007 0.0006
Echinococcus multilocularis cpg binding protein 0.0098 0.0174 0.0174
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0017 0.0008 0.0008
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0054 0.1036
Mycobacterium ulcerans hypothetical protein 0.0177 0.0336 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0194 0.037 0.037
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.0211 0.0211
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0042 0.0042
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0046 0.0253
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0094 0.0094
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.0063 0.0063
Echinococcus granulosus 7TM GPCR rhodopsin 0.0017 0.0008 0.0008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0054 0.0299
Echinococcus granulosus voltage gated potassium channel 0.0016 0.0007 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0012 0.0173
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0031 0.0031
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0075 0.144
Brugia malayi hypothetical protein 0.0106 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0061 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0017 0.0008 0.0007
Schistosoma mansoni cytochrome P450 0.0019 0.0012 0.0012
Leishmania major protein kinase, putative 0.0019 0.0013 0.0048
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0311
Schistosoma mansoni hypothetical protein 0.035 0.0689 0.0689
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0071 0.0295
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0028 0.0148
Brugia malayi Cytochrome P450 family protein 0.0019 0.0012 0.0012
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0834 0.1676 0.1676
Schistosoma mansoni hypothetical protein 0.0033 0.0042 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0012 0.0173
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0008 0.0008
Echinococcus granulosus alpha 1A adrenergic receptor 0.0017 0.0008 0.0008
Echinococcus multilocularis Protein lozenge 0.0059 0.0094 0.0094
Schistosoma mansoni neuropeptide receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0105 0.0105
Onchocerca volvulus Alhambra homolog 0.0035 0.0046 0.0045
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0133 0.0133
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0058 0.0092 0.0385
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.0092 0.0092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0015 0.0015
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0012 0.0012
Brugia malayi CHD4 protein 0.0019 0.0013 0.0013
Schistosoma mansoni inositol monophosphatase 0.0039 0.0054 0.0054
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0012 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0012 0.0173
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0084 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0012 0.0051
Loa Loa (eye worm) hypothetical protein 0.006 0.0097 0.0097
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0038 0.0227
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0017 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0087 0.0087
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0014 0.0084
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0031 0.0825
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.009 0.0089
Brugia malayi Dopamine receptor protein 2 0.0017 0.0008 0.0008
Schistosoma mansoni bromodomain containing protein 0.0069 0.0115 0.0115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0108 0.0108
Plasmodium vivax SET domain protein, putative 0.0035 0.0046 0.0253
Echinococcus multilocularis survival motor neuron protein 1 0.0496 0.0986 0.0986
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0056 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0046 0.089
Plasmodium falciparum amino acid transporter, putative 0.0834 0.1676 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Leishmania major ATP-dependent phosphofructokinase 0.0116 0.0211 0.0891
Brugia malayi G protein-coupled receptor F59B2.13 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.0012 0.0257
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0122 0.0122
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.004 0.0781
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1165 0.2352 0.2352
Schistosoma mansoni hypothetical protein 0.0035 0.0046 0.0046
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0007 0.0006
Onchocerca volvulus 0.0101 0.0181 0.0179
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0013 0.005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0008 0.0008
Schistosoma mansoni alpha-1 adrenergic receptor 0.0017 0.0008 0.0008
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0017 0.0016
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0019 0.0013 0.0013
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0015 0.0015
Onchocerca volvulus 0.002 0.0015 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0032 0.0616
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.0012 0.0257
Loa Loa (eye worm) TYRA-2 protein 0.0017 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.0012 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0311
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0042 0.0042
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0038 0.0973
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0001 0.0024
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0015 0.0015
Loa Loa (eye worm) melatonin receptor type 1A 0.0017 0.0008 0.0008
Brugia malayi Dopamine receptor protein 1 0.0017 0.0008 0.0008
Echinococcus granulosus 6 phosphofructokinase 0.0116 0.0211 0.0211
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0108 0.0108
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.003 0.003
Plasmodium falciparum transporter, putative 0.0834 0.1676 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.001
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0311
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0004 0.0095
Schistosoma mansoni hypothetical protein 0.0033 0.0042 0.0042
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0017 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0008 0.0008
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0017 0.0008 0.0008
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0138 0.0257 0.0257
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.004 0.0781
Echinococcus granulosus FTZ F1 alpha 0.002 0.0015 0.0015
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0013 0.005
Echinococcus granulosus allatostatin A receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0017 0.0017
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0834 0.1676 0.1676
Echinococcus multilocularis sex peptide receptor 0.0017 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0071 0.137
Schistosoma mansoni inositol monophosphatase 0.0039 0.0054 0.0054
Schistosoma mansoni hypothetical protein 0.0021 0.0017 0.0017
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0017 0.0008 0.0007
Echinococcus multilocularis serotonin transporter 0.4914 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0311
Loa Loa (eye worm) hypothetical protein 0.0834 0.1676 0.1676
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0057 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) RNA binding protein 0.0064 0.0105 0.0105
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0004 0.001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.004 0.0781
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0052 0.0052
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0008 0.0008
Echinococcus granulosus neuropeptide receptor 0.0017 0.0008 0.0008
Schistosoma mansoni patched 1 0.0088 0.0153 0.0153
Onchocerca volvulus 0.0021 0.0017 0.0015
Echinococcus granulosus g protein coupled receptor 0.0017 0.0008 0.0008
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0015 0.0015
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0014 0.0045
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.0012 0.0257
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0008 0.0008
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0161 0.0161
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0045 0.0066 0.0066
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.4914 1 1
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0105 0.0105
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0045 0.0066 0.0275
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0053 0.0081 0.0081
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0005 0.0005
Echinococcus multilocularis dro:myosuppressin receptor 0.0017 0.0008 0.0008
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0063 0.0063
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0056 0.106
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0735
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Brugia malayi Serotonin receptor 0.0017 0.0008 0.0008
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0205 0.0392 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0735
Loa Loa (eye worm) hypothetical protein 0.008 0.0137 0.0137
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0227 0.0437 0.0437
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0002 0.0004
Echinococcus granulosus orexin receptor type 2 0.0017 0.0008 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0084 0.162
Loa Loa (eye worm) hypothetical protein 0.0834 0.1676 0.1676
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0015 0.0014
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0015 0.0015
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0044 0.0063 0.0063
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.0092 0.0092
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0063 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0126
Loa Loa (eye worm) hypothetical protein 0.0072 0.0121 0.0121
Mycobacterium ulcerans hypothetical protein 0.0021 0.0017 0.0402
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0012 0.0173
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0056 0.0056
Trichomonas vaginalis set domain proteins, putative 0.0266 0.0517 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0028 0.017
Onchocerca volvulus 0.0014 0.0004 0.0002
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0834 0.1676 1
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0105 0.0105
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0071 0.0071
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0015 0.0015
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0094 0.0165 0.0165
Brugia malayi hypothetical protein 0.0834 0.1676 0.1676
Echinococcus granulosus lamin 0.0057 0.009 0.0089
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0015 0.0015
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0004 0.0022
Echinococcus granulosus G protein coupled receptor 139 0.0017 0.0008 0.0008
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0075 0.3503
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0221 0.0221
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0049 0.1373
Brugia malayi hypoxia-induced factor 1 0.0159 0.0298 0.0298
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0138 0.0257 0.1086
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0002 0.0004
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.001 0.001
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0074 0.0074
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0037 0.0713
Onchocerca volvulus 0.0017 0.0008 0.0007
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0087 0.0087
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.0012 0.0257
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0087 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0012 0.0173
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0056 0.1575
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0015 0.0015
Schistosoma mansoni amine GPCR 0.0017 0.0008 0.0008
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0834 0.1676 0.1676
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.0012 0.0257
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0047 0.0917
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.004 0.0056 0.1575
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0071 0.0286
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0039 0.0753
Loa Loa (eye worm) hypothetical protein 0.0108 0.0194 0.0194
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0036 0.0036
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.0181 0.018
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0038 0.0206
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0017 0.0016
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0075 0.2139
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0063 0.0063
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0105 0.3045
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0159 0.0299 0.1267
Leishmania major protein kinase, putative 0.0014 0.0002 0.0004
Toxoplasma gondii endonuclease IV APN 0.008 0.0137 0.0799
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0105 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0027 0.0028 0.0115
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0051 0.0212
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.0046 0.0046
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0017 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0032 0.0616
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0071 0.0296
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.0092 0.0092
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0046 0.0253
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0004 0.001
Mycobacterium ulcerans beta-lactamase 0.004 0.0056 0.1575
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.0012 0.0257
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0012 0.0173
Echinococcus granulosus Ankyrin 0.0015 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0987
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0031 0.0605
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0013 0.0013
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0004 0.001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0834 0.1676 0.1676
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0013 0.004
Brugia malayi intermediate filament protein 0.0057 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.1165 0.2352 0.2352
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0056 0.0223
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0012 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0007 0.0012
Onchocerca volvulus 0.0105 0.0188 0.0187
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0153 0.0153
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0211 0.4078
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0153 0.2967
Schistosoma mansoni sodium-dependent amino acid transporter 0.0834 0.1676 0.1676
Echinococcus granulosus fmrfamide receptor 0.0017 0.0008 0.0008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0021 0.0404
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0084 0.0084
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0227 0.0437 0.0437
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0015 0.0015
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0071 0.0295
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0016 0.0006 0.0006
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0038 0.0206
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0116 0.0211 0.4197
Brugia malayi M-phase phosphoprotein, mpp8 0.0106 0.019 0.019
Onchocerca volvulus 0.0182 0.0346 0.0345
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0094 0.0165 0.0165
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0108 0.0108
Onchocerca volvulus 0.0057 0.009 0.0088
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0001 0.0024
Echinococcus multilocularis somatostatin receptor 0.0017 0.0008 0.0008
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0017 0.0008 0.0008
Brugia malayi beta-lactamase family protein 0.004 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0072 0.0121 0.0121
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0031 0.0031
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.0211 0.0211
Echinococcus multilocularis neuropeptide FF receptor 2 0.0017 0.0008 0.0008
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1165 0.2352 1
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.008 0.0137 0.2706
Schistosoma mansoni hypothetical protein 0.0108 0.0194 0.0194
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0056 0.0056
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0031 0.0126
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0015 0.0015
Schistosoma mansoni voltage-gated cation channel 0.0045 0.0066 0.0066
Schistosoma mansoni lamin 0.0057 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0049 0.0075 0.0075
Onchocerca volvulus 0.0047 0.007 0.0069
Mycobacterium ulcerans lipase LipD 0.004 0.0056 0.1575
Brugia malayi beta-lactamase family protein 0.004 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0031 0.0031
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0049 0.0294
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0159 0.0299 0.1258
Echinococcus granulosus expressed conserved protein 0.0192 0.0367 0.0366
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0016 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Brugia malayi nuclear hormone receptor 0.002 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0987
Loa Loa (eye worm) hypothetical protein 0.0834 0.1676 0.1676
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0028 0.0115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0037 0.005 0.005
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.003 0.003
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0015 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0087 0.0087
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0105 0.044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.004 0.0781
Schistosoma mansoni netrin receptor unc5 0.0015 0.0005 0.0005
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0038 0.0206
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0015 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0834 0.1676 0.1676
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0075 0.1908
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0834 0.1676 0.1676
Schistosoma mansoni hypothetical protein 0.1295 0.2615 0.2615
Plasmodium vivax hypothetical protein, conserved 0.0834 0.1676 1
Schistosoma mansoni hypothetical protein 0.0101 0.0181 0.0181
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.0211 0.0211
Brugia malayi CXXC zinc finger family protein 0.0091 0.016 0.0159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0596 0.1189 0.1189
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Brugia malayi isocitrate dehydrogenase 0.0019 0.0013 0.0013
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.0012 0.0257
Onchocerca volvulus 0.0017 0.0008 0.0007
Brugia malayi SET domain containing protein 0.0015 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0017 0.0008 0.0007
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0004 0.0004
Echinococcus multilocularis Ankyrin 0.0015 0.0005 0.0005
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0105 0.0105
Schistosoma mansoni rab6-interacting 0.0021 0.0017 0.0017
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0031 0.0031
Loa Loa (eye worm) inositol-1 0.0039 0.0054 0.0054
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0013 0.0013
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0124 0.0228 0.0228
Schistosoma mansoni opsin-like receptor 0.0017 0.0008 0.0008
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0045 0.0066 0.0066
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0012 0.0173
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0116 0.0211 0.0173
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0017 0.0077
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0337 0.0661 0.2799
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0007 0.0022
Brugia malayi jmjC domain containing protein 0.0115 0.0209 0.0209
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0075 0.0075
Onchocerca volvulus 0.0017 0.0008 0.0007
Brugia malayi hypothetical protein 0.0182 0.0346 0.0346
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0001 0.0024
Loa Loa (eye worm) oxidoreductase 0.0014 0.0004 0.0004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0034 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0012 0.0173
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0834 0.1676 0.1676
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0005 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0045 0.0841
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0048 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0012 0.0173
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.0211 0.538
Onchocerca volvulus 0.0467 0.0927 0.0926
Brugia malayi sulfakinin receptor protein 0.0017 0.0008 0.0008
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0138 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0987
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Brugia malayi ecdysteroid receptor 0.002 0.0015 0.0015
Echinococcus multilocularis tumor protein p63 0.0717 0.1437 0.1437
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0056 0.1082
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0087 0.0087
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0138 0.0257 0.0257
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0017 0.0008 0.0008
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0071 0.0285
Onchocerca volvulus 0.004 0.0056 0.0055
Brugia malayi Serotonin receptor 0.0017 0.0008 0.0008
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0005 0.0005
Echinococcus multilocularis GPCR, family 2 0.0033 0.0042 0.0042
Brugia malayi hypothetical protein 0.0027 0.0028 0.0028
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.002 0.0019
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0001 0.0024
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0009 0.0009
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.002 0.0376
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0017 0.0008 0.0008
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0053
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0038 0.0227
Echinococcus multilocularis peregrin 0.0038 0.0051 0.0051
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.0189 0.0189
Schistosoma mansoni myosin xvIII 0.0017 0.0008 0.0008
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0015 0.0006 0.0006
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0005 0.0004
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0834 0.1676 0.1676
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0056 0.106
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0046 0.089
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0106 0.019 0.0188
Schistosoma mansoni hypothetical protein 0.0085 0.0147 0.0147
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.0012 0.0257
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0008 0.0008
Brugia malayi 6-phosphofructokinase 0.0116 0.0211 0.0211
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.0189 0.0189
Echinococcus multilocularis allatostatin A receptor 0.0017 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.0012 0.0257
Schistosoma mansoni lipoxygenase 0.0087 0.0152 0.0152
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0001 0.0024
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0046 0.0046
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0105 0.0105
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0015 0.0015
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0012 0.0173
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0054 0.1036
Brugia malayi hypothetical protein 0.0467 0.0927 0.0927
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0208 0.0398 0.0398
Onchocerca volvulus 0.0049 0.0075 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0056 0.0233
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0012
Echinococcus granulosus Niemann Pick C1 protein 0.0293 0.0571 0.0571
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0017 0.0008 0.0008
Brugia malayi Bromodomain containing protein 0.0038 0.0051 0.0051
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0105 0.3045
Echinococcus multilocularis sodium and chloride dependent glycine 0.0834 0.1676 0.1676
Onchocerca volvulus 0.0017 0.0008 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0009 0.0031
Mycobacterium ulcerans endonuclease IV 0.008 0.0137 0.4021
Echinococcus granulosus transcription factor Dp 1 0.008 0.0138 0.0138
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0088 0.0153 0.0153
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.0012 0.0257
Schistosoma mansoni hypothetical protein 0.0033 0.0042 0.0042
Brugia malayi MAP kinase sur-1 0.0054 0.0084 0.0084
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0012 0.0173
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0015 0.0014
Echinococcus granulosus tar DNA binding protein 0.0064 0.0105 0.0105
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0045 0.0066 0.0265
Loa Loa (eye worm) hypothetical protein 0.0172 0.0325 0.0325
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0046 0.0254
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.0404
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0017 0.0009 0.0053
Schistosoma mansoni loxhd1 0.0021 0.0017 0.0017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0008 0.0008
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0834 0.1676 0.1676
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.008 0.0137 0.0137
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0049 0.0075 0.2139
Echinococcus multilocularis G-protein coupled receptor, putative 0.0017 0.0008 0.0008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0001 0.0024
Echinococcus granulosus GPCR family 2 0.0033 0.0042 0.0042
Mycobacterium leprae putative cytochrome p450 0.0019 0.0012 0.0519
Echinococcus multilocularis voltage dependent calcium channel 0.0045 0.0066 0.0066
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0017 0.0008 0.0008
Brugia malayi RE15519p 0.0017 0.0008 0.0008
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0031 0.0126
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0015 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0075 0.0075
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0028 0.0105
Echinococcus granulosus sex peptide receptor 0.0017 0.0008 0.0008
Echinococcus granulosus serotonin receptor 0.0017 0.0008 0.0008
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0094 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0116 0.0211 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0058 0.0058
Brugia malayi PAS domain containing protein 0.0051 0.0079 0.0079
Leishmania major mitochondrial DNA polymerase beta 0.0337 0.0661 0.2806
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0034 0.0034
Loa Loa (eye worm) calcium channel 0.0045 0.0066 0.0066
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0017 0.0749
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0084 0.0351
Leishmania major hypothetical protein, conserved 0.004 0.0056 0.0233
Schistosoma mansoni hypothetical protein 0.0085 0.0147 0.0147
Brugia malayi hypothetical protein 0.0172 0.0325 0.0325
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0042 0.0042
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0556 0.1109 0.1109
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0133 0.0133
Brugia malayi ORL1-like opioid receptor 0.0017 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0026 0.0509
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0015 0.0015
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0834 0.1676 0.1676
Brugia malayi Tachykinin-like peptides receptor 99D 0.0017 0.0008 0.0008
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0051 0.0202
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0013 0.019
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0015 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.0834 0.1676 0.1676
Echinococcus granulosus hypothetical protein 0.0017 0.0008 0.0008
Schistosoma mansoni lipoxygenase 0.0124 0.0228 0.0228
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0084 0.0351
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0015 0.0015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.004 0.0781
Echinococcus granulosus 7tm_1 domain containing protein 0.0017 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0026 0.0507
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0084 0.162
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0056 0.106
Loa Loa (eye worm) hypothetical protein 0.0045 0.0066 0.0066
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0004 0.0004
Onchocerca volvulus 0.0014 0.0004 0.0002
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0084 0.0084
Brugia malayi larval opioid receptor 0.0017 0.0008 0.0008
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0834 0.1676 0.1676
Onchocerca volvulus 0.0017 0.0008 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0004 0.0004
Brugia malayi MH2 domain containing protein 0.0121 0.0221 0.0221
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0071 0.0071
Brugia malayi hypothetical protein 0.0021 0.0017 0.0016
Trypanosoma cruzi ISWI complex protein 0.0015 0.0006 0.0019
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0043 0.0063 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Conserved protein 0.004 0.0056 0.106
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0015 0.0015
Brugia malayi PHD-finger family protein 0.0019 0.0012 0.0012
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0834 0.1676 0.1676
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.1603
Schistosoma mansoni adenoreceptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0182 0.0346 0.0346
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0028 0.0115
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.009 0.0089
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0071 0.0071
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0153 0.0153
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.0211 0.0891
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0008 0.0008
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0007 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.004 0.0781
Brugia malayi putative neuropeptide receptor 0.0017 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0987
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0054 0.137
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0075 0.2139
Schistosoma mansoni hypothetical protein 0.0205 0.0392 0.0392
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0049 0.0273
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0311
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0075 0.2139
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0016
Echinococcus granulosus voltage dependent calcium channel 0.0045 0.0066 0.0066
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0028 0.0148
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0001 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0042 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0001 0.0024
Echinococcus granulosus Niemann Pick C1 protein 0.0205 0.0392 0.0392
Plasmodium vivax amine transporter, putative 0.0834 0.1676 1
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0052 0.0052
Loa Loa (eye worm) serotonin transporter b 0.4914 1 1
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0031 0.0117
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0048 0.0048
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0013 0.0056
Brugia malayi nuclear receptor NHR-88 0.002 0.0015 0.0015
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0054 0.0222
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0079 0.0079
Onchocerca volvulus 0.0058 0.0092 0.009
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0017 0.0008 0.0008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.0042
Brugia malayi Inositol-1 0.0039 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0016
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0056 0.1082
Schistosoma mansoni cellular tumor antigen P53 0.0105 0.0188 0.0188
Giardia lamblia GTOR 0.0047 0.0071 0.7169
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0045 0.0066 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0026 0.0509
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0015 0.0015
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0012 0.0036
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0834 0.1676 0.1676
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0056 0.106
Loa Loa (eye worm) MBCTL1 0.0066 0.0108 0.0108
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0017 0.0008 0.0008
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0045 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0049 0.0075 0.0075
Plasmodium falciparum phd finger protein, putative 0.0035 0.0046 0.0274
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0209 0.0209
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0005 0.0005
Trypanosoma cruzi ISWI complex protein 0.0015 0.0006 0.0019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0015 0.0015
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0834 0.1676 0.1676
Mycobacterium tuberculosis Conserved protein 0.004 0.0056 0.106
Loa Loa (eye worm) beta-lactamase 0.004 0.0056 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0834 0.1676 0.1676
Schistosoma mansoni nuclear hormone receptor 0.002 0.0015 0.0015
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0007 0.0022
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0012 0.0173
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0007 0.0007
Brugia malayi cytochrome P450 0.0019 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0205 0.0392 0.0392
Brugia malayi steroid hormone receptor 0.002 0.0015 0.0015
Echinococcus multilocularis musashi 0.0057 0.009 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0015 0.0015
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0023 0.0023
Loa Loa (eye worm) hypoxia-induced factor 1 0.0159 0.0298 0.0298
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0015 0.0015
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0012 0.0012
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.0012 0.0257
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0012 0.0173
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2542 0.516 0.5159
Loa Loa (eye worm) hypothetical protein 0.0037 0.005 0.005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0054 0.1036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0046 0.089
Loa Loa (eye worm) hypothetical protein 0.0072 0.012 0.012
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0002 0.0004
Echinococcus granulosus death domain containing protein 0.0015 0.0005 0.0005
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0052 0.1444
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0056 0.0056
Leishmania major cytochrome p450-like protein 0.0019 0.0012 0.0046
Brugia malayi Bromodomain containing protein 0.0039 0.0053 0.0053
Echinococcus granulosus intermediate filament protein 0.0057 0.009 0.0089
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0834 0.1676 0.1676
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Echinococcus multilocularis protein patched 0.0088 0.0153 0.0153
Echinococcus granulosus neuropeptide FF receptor 2 0.0017 0.0008 0.0008
Leishmania major cytochrome p450-like protein 0.0028 0.0031 0.0126
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0056 0.1082
Loa Loa (eye worm) hypothetical protein 0.0058 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0045 0.0066 0.0066
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0075 0.2139
Onchocerca volvulus 0.004 0.0056 0.0055
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0008 0.0008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0012 0.0173
Echinococcus granulosus single minded 2 0.0042 0.0059 0.0059
Echinococcus multilocularis serotonin receptor 0.0017 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0017 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.1603
Echinococcus multilocularis protein dispatched 1 0.01 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0017 0.0402
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0012 0.0173
Loa Loa (eye worm) voltage-dependent calcium channel 0.0045 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0015 0.0015
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0008 0.0008
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0013 0.004
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0017 0.0008 0.0008
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0049
Schistosoma mansoni biogenic amine receptor 0.0017 0.0008 0.0008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0017 0.0008 0.0008
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0108 0.0108
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0071 0.1809
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0834 0.1676 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0159 0.0299 0.1267
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0012 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0126
Echinococcus multilocularis lamin dm0 0.0057 0.009 0.0089
Echinococcus granulosus sodium and chloride dependent glycine 0.0834 0.1676 0.1676
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0056 0.1082
Loa Loa (eye worm) phosphofructokinase 0.0116 0.0211 0.0211
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0138 0.0257 0.0257
Brugia malayi PHD-finger family protein 0.0035 0.0046 0.0046
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0017 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0008 0.0008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0087 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0311
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0056 0.0056
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0834 0.1676 0.1676
Onchocerca volvulus 0.0017 0.0008 0.0007
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Onchocerca volvulus Neuropeptide F receptor homolog 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0108 0.0108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.004 0.0781
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0046 0.089
Schistosoma mansoni amine GPCR 0.0017 0.0008 0.0008
Schistosoma mansoni zinc finger protein 0.0015 0.0006 0.0006
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0013 0.0078
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0004 0.0004
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0337 0.0661 0.2806
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0045 0.0841
Onchocerca volvulus 0.0834 0.1676 0.1675
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0046 0.0253
Brugia malayi mbt repeat family protein 0.0058 0.0092 0.0092
Schistosoma mansoni jumonji/arid domain-containing protein 0.005 0.0076 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0311
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.0211 0.0882
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0004 0.0004
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0084 0.0351
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0007 0.0007
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0031 0.0031
Onchocerca volvulus 0.0017 0.0008 0.0007
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0071 0.0286
Mycobacterium leprae Probable lipase LipE 0.004 0.0056 0.2609
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0211 0.4078
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0017 0.0016
Echinococcus granulosus g protein coupled receptor 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0075 0.144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0046 0.089
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0045 0.0844
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0256 0.0497 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0012 0.0012
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0007 0.0012
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0008 0.0008
Echinococcus granulosus RUN 0.0021 0.0017 0.0016
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0138 0.0257 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0031 0.0605
Onchocerca volvulus 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0028
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0007 0.0022
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0008 0.0008
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0002 0.0004
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0056 0.1575
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0001 0.0024
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.0189 0.0189
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0047 0.007 0.007
Echinococcus multilocularis dnaJ subfamily B 0.1295 0.2615 0.2615
Brugia malayi Melatonin receptor type 1A 0.0017 0.0008 0.0008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0042 0.0042
Brugia malayi PHD-finger family protein 0.003 0.0036 0.0036
Trichomonas vaginalis helicase, putative 0.0021 0.0016 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0026 0.0507
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0051 0.0987
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0138 0.0257 0.6551
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0017 0.0016
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0049 0.0286
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0126
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0056 0.106
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0013 0.0013
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0467 0.0927 0.0927
Loa Loa (eye worm) hypothetical protein 0.0834 0.1676 0.1676
Onchocerca volvulus 0.0057 0.009 0.0088
Echinococcus multilocularis geminin 0.0205 0.0392 0.0392
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0045 0.0066 0.0066
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0081 0.0081
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0038 0.0206
Brugia malayi Bromodomain containing protein 0.0081 0.014 0.0139
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0023 0.0023
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0015 0.0015
Trypanosoma brucei C-8 sterol isomerase, putative 0.1165 0.2352 1
Brugia malayi RNA binding protein 0.0064 0.0105 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0026 0.0507
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0003 0.0003
Toxoplasma gondii histone lysine methyltransferase SET1 0.0176 0.0333 0.1968
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0834 0.1676 0.1676
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0008 0.0008
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0105 0.0605
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0071 0.0296
Echinococcus multilocularis Niemann Pick C1 protein 0.0293 0.0571 0.0571
Brugia malayi Death domain containing protein 0.0015 0.0005 0.0005
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0071 0.0071
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0071 0.0296
Echinococcus multilocularis lamin 0.0057 0.009 0.0089
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.0012 0.0257
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0004 0.0004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0054 0.0222
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0008 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0087 0.0087
Echinococcus granulosus survival motor neuron protein 1 0.0496 0.0986 0.0986
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0045 0.2098
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.1603
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0071 0.137
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.0451 0.0451
Brugia malayi 6-phosphofructokinase 0.0116 0.0211 0.0211
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0311
Echinococcus granulosus sodium and chloride dependent glycine 0.0834 0.1676 0.1676
Brugia malayi neuropeptide F receptor 0.0017 0.0008 0.0008
Schistosoma mansoni cpg binding protein 0.0098 0.0174 0.0174
Echinococcus granulosus lamin dm0 0.0057 0.009 0.0089
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0031 0.0031
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0005 0.0007
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0138 0.0257 0.1078
Plasmodium vivax hypothetical protein, conserved 0.004 0.0056 0.0313
Toxoplasma gondii hypothetical protein 0.0054 0.0085 0.0486
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0092 0.0092
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0008 0.0008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0834 0.1676 0.1676
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0046 0.0046
Giardia lamblia PHD finger protein 15 0.0035 0.0046 0.1726
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni opsin-like receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0467 0.0927 0.0927
Schistosoma mansoni hypothetical protein 0.0085 0.0147 0.0147
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0015 0.0015
Schistosoma mansoni coup transcription factor 0.002 0.0015 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.0835 0.1677 0.1677
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0013 0.0013
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0017 0.0008 0.0008
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0054 0.0213
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0138 0.0257 0.1086
Brugia malayi GnHR receptor homolog 0.0017 0.0008 0.0008
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0834 0.1676 0.1676
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0012 0.0046
Brugia malayi G-protein coupled receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0056 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.4914 1 1
Loa Loa (eye worm) intermediate filament protein 0.0057 0.009 0.0089
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0084 0.0084
Schistosoma mansoni neuropeptide receptor 0.0017 0.0008 0.0008
Echinococcus granulosus dro:myosuppressin receptor 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0017 0.0008 0.0007
Brugia malayi jmjC domain containing protein 0.005 0.0076 0.0075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0087 0.0087
Onchocerca volvulus 0.0021 0.0017 0.0015
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0084 0.0341
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0075 0.0312
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0735
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0105 0.0105
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0071 0.0071
Brugia malayi mbt repeat family protein 0.0058 0.0092 0.0092
Echinococcus multilocularis neuropeptide receptor A26 0.0496 0.0987 0.0987
Schistosoma mansoni zinc finger protein 0.0025 0.0025 0.0025
Schistosoma mansoni biogenic amine receptor 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0045 0.0841
Brugia malayi G protein-coupled receptor 0.0017 0.0008 0.0008
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0108 0.0108
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.0012 0.0257
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0075 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0046 0.089
Loa Loa (eye worm) runx1 0.0059 0.0094 0.0094
Brugia malayi hypothetical protein 0.0017 0.0008 0.0008
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0019 0.0013 0.0013
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0001 0.0001
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0054 0.0054
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0105 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0057 0.1096
Schistosoma mansoni hypothetical protein 0.0205 0.0392 0.0392
Schistosoma mansoni opsin-like receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0076 0.0075
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0017 0.0008 0.0008
Schistosoma mansoni single-minded 0.0051 0.0079 0.0079
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.0012 0.0257
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0015 0.0015
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.0211 0.538
Loa Loa (eye worm) CXXC zinc finger family protein 0.0091 0.016 0.0159
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0014 0.0004 0.0111
Schistosoma mansoni neuropeptide receptor 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0014 0.0004 0.0002
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.1603
Brugia malayi hypothetical protein 0.0496 0.0986 0.0986
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0015 0.0015
Echinococcus granulosus somatostatin receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0106 0.019 0.0188
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0211 0.4078
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0008 0.0008
Toxoplasma gondii hypothetical protein 0.0834 0.1676 1
Schistosoma mansoni cpg binding protein 0.0098 0.0174 0.0174
Brugia malayi F/Y-rich N-terminus family protein 0.0042 0.0061 0.0061
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0045 0.0066 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0056 0.0233
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0137 0.0799
Echinococcus multilocularis 6 phosphofructokinase 0.0116 0.0211 0.0211
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0105 0.205
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0004 0.0069
Schistosoma mansoni neuropeptide receptor 0.0017 0.0008 0.0008
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0092 0.0092
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0259 0.0503 0.0503
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0016 0.0007 0.0007
Schistosoma mansoni thyroid hormone receptor 0.002 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0026 0.0509
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0046 0.0046
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0028 0.017
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0017 0.0008 0.0008
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0034 0.0034
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0008 0.0008
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0009 0.0009
Toxoplasma gondii ABC1 family protein 0.004 0.0056 0.0313
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0004 0.0069
Echinococcus multilocularis sodium and chloride dependent glycine 0.0834 0.1676 0.1676
Onchocerca volvulus 0.004 0.0056 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0126
Onchocerca volvulus 0.0091 0.016 0.0158
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0012 0.0046
Brugia malayi AKH receptor 0.0017 0.0008 0.0008
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0017 0.0099
Echinococcus granulosus cpg binding protein 0.0098 0.0174 0.0174
Brugia malayi CHE-14 protein 0.0088 0.0153 0.0153
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0014 0.0004 0.0111
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0105 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0032 0.0616
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0834 0.1676 0.1676
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0008 0.0008
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0017 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0735
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0001 0.0001
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0004 0.0004
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Brugia malayi Uncoordinated protein 44 0.0015 0.0005 0.0005
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.003
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0012 0.0173
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0056
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0496 0.0986 0.0986
Schistosoma mansoni hypothetical protein 0.0021 0.0017 0.0017
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0075 0.1908
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0054 0.5
Onchocerca volvulus 0.0017 0.0008 0.0007
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0011 0.0011
Echinococcus granulosus serotonin transporter 0.4914 1 1
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0008 0.0008
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0105 0.0189 0.0189
Onchocerca volvulus 0.0017 0.0008 0.0007
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0008 0.0008

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.7943 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.6109 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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