Detailed information for compound 1607429

Basic information

Technical information
  • TDR Targets ID: 1607429
  • Name: N-[1-(2-chlorophenyl)ethylideneamino]pyridine -4-carboxamide
  • MW: 273.718 | Formula: C14H12ClN3O
  • H donors: 1 H acceptors: 2 LogP: 2.61 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccncc1)N/N=C(/c1ccccc1Cl)\C
  • InChi: 1S/C14H12ClN3O/c1-10(12-4-2-3-5-13(12)15)17-18-14(19)11-6-8-16-9-7-11/h2-9H,1H3,(H,18,19)/b17-10+
  • InChiKey: QZWHCEOEMMVVBN-LICLKQGHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[1-(2-chlorophenyl)ethylideneamino]-4-pyridinecarboxamide
  • N-[1-(2-chlorophenyl)ethylideneamino]isonicotinamide
  • N'-(1-(2-chlorophenyl)ethylidene)isonicotinohydrazide
  • NCI63135
  • NCIStruc1_000628
  • ZINC00299526
  • NCIStruc2_000553
  • NSC63135
  • NCI60_010229
  • ZINC04743963

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0324 0.0464
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0085 0.0183 0.0424
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0005 0.0008
Mycobacterium leprae Conserved hypothetical protein 0.0793 0.2122 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0102 0.1112
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0056 0.0102 0.0387
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0005 0.0011
Echinococcus multilocularis disintegrin and metalloproteinase 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0203 0.0505 0.1955
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0291 0.0674
Trichomonas vaginalis conserved hypothetical protein 0.0958 0.2572 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0005 0.0005
Plasmodium falciparum importin beta, putative 0.002 0.0004 0.0015
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.024 0.0934
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0069 0.0138 0.0206
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.006 0.0115 0.0115
Schistosoma mansoni memapsin-2 (A01 family) 0.1305 0.3521 0.816
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0029 0.0031 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0005 0.0008
Schistosoma mansoni cathepsin D (A01 family) 0.0475 0.1251 0.2899
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0264 0.0673 0.156
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0056 0.0102 0.0151
Loa Loa (eye worm) hypothetical protein 0.003 0.0032 0.0113
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0008 0.0036
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0044 0.0072 0.0102
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0195 0.0484 0.0484
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0005 0.0008
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0958 0.2572 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0062 0.0119 0.0453
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0366 0.0953 0.1479
Loa Loa (eye worm) hypothetical protein 0.0038 0.0053 0.0195
Loa Loa (eye worm) carboxylesterase 0.0406 0.1061 0.4116
Echinococcus granulosus Protein patched homolog 1 0.0038 0.0053 0.0076
Echinococcus multilocularis adam 0.0034 0.0042 0.0042
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0021 0.0008 0.0045
Schistosoma mansoni myelin transcription factor 1 myt1 0.0042 0.0064 0.0149
Leishmania major hypothetical protein, conserved 0.0038 0.0054 0.0563
Entamoeba histolytica hypothetical protein 0.0022 0.0009 0.0122
Loa Loa (eye worm) acetylcholinesterase 1 0.0406 0.1061 0.4116
Echinococcus multilocularis smad 0.0029 0.0031 0.0031
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0264 0.0673 0.2609
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0038 0.0053 0.0195
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0085 0.0183 0.0424
Loa Loa (eye worm) hypothetical protein 0.0035 0.0046 0.0169
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0291 0.0748 0.0748
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0008 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0052 0.0202
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.236 0.641 1
Schistosoma mansoni hypothetical protein 0.0036 0.0049 0.0114
Echinococcus granulosus smad 0.0029 0.0031 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0167
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.034 0.1312
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.002 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0008
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0111 0.0254 0.0254
Trypanosoma cruzi DNA repair protein, putative 0.0023 0.0013 0.0098
Brugia malayi hypothetical protein 0.0085 0.0183 0.07
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0264 0.0673 0.0673
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.005 0.0087 0.0941
Echinococcus granulosus Niemann Pick C1 protein 0.0088 0.019 0.0273
Trypanosoma cruzi PAB1-binding protein , putative 0.008 0.0168 0.1862
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0085 0.0183 0.07
Brugia malayi Thioredoxin reductase 0.0161 0.039 0.1505
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0063 0.0123 0.0284
Loa Loa (eye worm) hypothetical protein 0.0069 0.0138 0.0524
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0008
Schistosoma mansoni tankyrase 0.0022 0.0009 0.0021
Echinococcus granulosus X box binding protein 1 0.0257 0.0653 0.0936
Loa Loa (eye worm) hypothetical protein 0.0044 0.0072 0.0267
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0005 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0005 0.0008
Brugia malayi Eukaryotic aspartyl protease family protein 0.0085 0.0183 0.07
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0028 0.0027 0.0038
Brugia malayi Cytochrome P450 family protein 0.003 0.0033 0.0117
Plasmodium falciparum plasmepsin IX 0.0085 0.0183 0.0711
Echinococcus granulosus transcription factor eb 0.0096 0.0213 0.0306
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0019 0.0003 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0106 0.024 0.0934
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0478 0.1107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0264 0.0673 0.156
Mycobacterium ulcerans lipase LipD 0.0106 0.024 0.3384
Trichomonas vaginalis set domain proteins, putative 0.0858 0.2299 0.8937
Mycobacterium tuberculosis Probable dehydrogenase 0.0366 0.0953 0.1479
Loa Loa (eye worm) carboxylesterase 0.0069 0.0138 0.0524
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0004 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0008 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0005 0.0008
Echinococcus granulosus thioredoxin glutathione reductase 0.0162 0.0393 0.0563
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0341 0.0883 0.0883
Echinococcus multilocularis ring and YY1 binding protein 0.0341 0.0883 0.0883
Brugia malayi Latrophilin receptor protein 2 0.0146 0.0351 0.1354
Trypanosoma brucei unspecified product 0.0031 0.0034 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0036
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0056 0.0102 0.0237
Brugia malayi Cytochrome P450 family protein 0.003 0.0033 0.0117
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0005 0.0007
Chlamydia trachomatis recombinase RecA 0.0075 0.0156 0.0216
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0072 0.077
Loa Loa (eye worm) hypothetical protein 0.0069 0.0138 0.0524
Loa Loa (eye worm) hypothetical protein 0.0106 0.024 0.0924
Trichomonas vaginalis mercuric reductase, putative 0.0056 0.0102 0.0398
Brugia malayi N-terminal motif family protein 0.0278 0.0711 0.2756
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0193
Loa Loa (eye worm) MH1 domain-containing protein 0.0029 0.0031 0.0108
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0005 0.0011
Echinococcus granulosus WGR domain containing protein 0.0091 0.0198 0.0283
Echinococcus granulosus expressed conserved protein 0.0082 0.0176 0.0252
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0005 0.0005
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0122 0.0283 0.0405
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0005 0.0008
Toxoplasma gondii aldehyde dehydrogenase 0.0136 0.0321 0.1248
Toxoplasma gondii preprocathepsin c precursor, putative 0.0082 0.0176 0.0682
Schistosoma mansoni cpg binding protein 0.0172 0.0419 0.0972
Schistosoma mansoni patched 1 0.0038 0.0053 0.0123
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0264 0.0673 0.0964
Plasmodium vivax aspartyl proteinase, putative 0.0195 0.0484 0.188
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0021 0.0008 0.0008
Trypanosoma brucei PAB1-binding protein , putative 0.008 0.0168 0.1869
Loa Loa (eye worm) hypothetical protein 0.0555 0.147 0.571
Echinococcus multilocularis SWI:SNF matrix associated 0.0958 0.2572 0.2572
Entamoeba histolytica hypothetical protein 0.0022 0.0009 0.0122
Chlamydia trachomatis DNA topoisomerase I 0.0958 0.2572 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.005 0.0193
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0161 0.039 0.06
Plasmodium vivax aspartyl protease, putative 0.0085 0.0183 0.0711
Loa Loa (eye worm) phosphatidylinositol 3 0.0063 0.0123 0.0466
Schistosoma mansoni TRABID protein (C64 family) 0.0341 0.0883 0.2046
Echinococcus multilocularis lamin 0.0062 0.0119 0.0119
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0072 0.0761
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0034 0.034
Echinococcus granulosus dnaJ subfamily B 0.1451 0.3923 0.562
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0122 0.0283 0.0283
Plasmodium falciparum plasmepsin I 0.0195 0.0484 0.188
Echinococcus granulosus poly (ADP ribose) polymerase 0.0045 0.0074 0.0106
Brugia malayi follicle stimulating hormone receptor 0.039 0.1017 0.3949
Brugia malayi hypothetical protein 0.0555 0.147 0.571
Echinococcus multilocularis sterol regulatory element binding protein 0.0038 0.0053 0.0053
Plasmodium falciparum glutathione reductase 0.0056 0.0102 0.0398
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0194 0.048 0.1113
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0102 0.1112
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0407 0.1065 0.1654
Toxoplasma gondii NADPH-glutathione reductase 0.0056 0.0102 0.0398
Schistosoma mansoni aldehyde dehydrogenase 0.0136 0.0321 0.0744
Echinococcus multilocularis para nitrobenzyl esterase 0.0069 0.0138 0.0138
Loa Loa (eye worm) follicle stimulating hormone receptor 0.039 0.1017 0.3949
Loa Loa (eye worm) hypothetical protein 0.0341 0.0883 0.3425
Schistosoma mansoni hypothetical protein 0.021 0.0525 0.1217
Echinococcus granulosus cytoplasmic intermediate filament protein 0.003 0.0032 0.0045
Brugia malayi brahma associated protein 60 kDa 0.0958 0.2572 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0005 0.0008
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0044 0.0072 0.0103
Onchocerca volvulus 0.0106 0.024 0.0917
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0078 0.0304
Trypanosoma cruzi DNA repair protein, putative 0.0023 0.0013 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0053 0.0206
Loa Loa (eye worm) acetyltransferase 0.0142 0.034 0.1312
Loa Loa (eye worm) hypothetical protein 0.0046 0.0076 0.0283
Trichomonas vaginalis esterase, putative 0.0106 0.024 0.0934
Brugia malayi SWIB/MDM2 domain containing protein 0.0958 0.2572 1
Echinococcus multilocularis musashi 0.0062 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0008
Entamoeba histolytica heat shock transcription factor, putative 0.0069 0.0139 0.186
Loa Loa (eye worm) hypothetical protein 0.0061 0.0116 0.0441
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0056 0.0102 0.0398
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.024 0.2683
Brugia malayi F/Y-rich N-terminus family protein 0.0055 0.0099 0.0376
Loa Loa (eye worm) thioredoxin reductase 0.0161 0.039 0.1505
Echinococcus multilocularis dna polymerase kappa 0.0044 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0341 0.0883 0.3425
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0068 0.0265
Brugia malayi WGR domain containing protein 0.0291 0.0748 0.2898
Echinococcus multilocularis dnaJ subfamily B 0.1451 0.3923 0.3923
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0108
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0072 0.0761
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0147 0.0353 0.0505
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0041 0.0147
Schistosoma mansoni hypothetical protein 0.0103 0.0231 0.0535
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.024 0.0934
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0021 0.0008 0.0045
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0029 0.0031 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0123 0.0476
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0069 0.0139 0.0522
Onchocerca volvulus 0.0069 0.0138 0.0517
Loa Loa (eye worm) mbt repeat family protein 0.0037 0.005 0.0184
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0085 0.0183 0.0424
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0341 0.0883 1
Loa Loa (eye worm) hypothetical protein 0.0146 0.0351 0.1354
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0005 0.0008
Leishmania major hypothetical protein, conserved 0.0341 0.0883 1
Brugia malayi hypothetical protein 0.008 0.0168 0.0643
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0087 0.0339
Plasmodium falciparum plasmepsin V 0.0085 0.0183 0.0711
Brugia malayi Tnks protein 0.0022 0.0009 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0478 0.1107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0069 0.0138 0.0524
Loa Loa (eye worm) hypothetical protein 0.0232 0.0585 0.2265
Echinococcus granulosus sterol regulatory element binding protein 0.0038 0.0053 0.0076
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0033 0.0323
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0072 0.077
Loa Loa (eye worm) hypothetical protein 0.0056 0.0103 0.039
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0195 0.0484 0.0693
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0092 0.02 0.0465
Brugia malayi T-complex protein 1, beta subunit 0.002 0.0005 0.0007
Loa Loa (eye worm) twinkle helicase 0.0077 0.016 0.0613
Schistosoma mansoni hypothetical protein 0.0036 0.0049 0.0114
Loa Loa (eye worm) hypothetical protein 0.0085 0.0183 0.07
Echinococcus multilocularis protein dispatched 1 0.0043 0.0068 0.0068
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0366 0.0953 0.1479
Brugia malayi mbt repeat family protein 0.0037 0.005 0.0184
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0041 0.0147
Schistosoma mansoni microtubule-associated protein tau 0.1595 0.4315 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0036
Trichomonas vaginalis glutathione reductase, putative 0.0056 0.0102 0.0398
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0012 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0036
Brugia malayi Carboxylesterase family protein 0.0069 0.0138 0.0524
Leishmania major hypothetical protein, conserved 0.0341 0.0883 1
Plasmodium falciparum plasmepsin VI 0.0195 0.0484 0.188
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0029 0.0031 0.0044
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0029 0.0031 0.1745
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0072 0.0761
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0062 0.0241
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0104 0.0234 0.0335
Schistosoma mansoni hypothetical protein 0.0341 0.0883 0.2046
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0063 0.0123 0.0123
Plasmodium vivax SET domain protein, putative 0.0111 0.0254 0.0989
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0478 0.1107
Schistosoma mansoni hypothetical protein 0.0146 0.0351 0.0813
Echinococcus granulosus SWI:SNF matrix associated 0.0958 0.2572 0.3685
Leishmania major hypothetical protein, conserved 0.0341 0.0883 1
Brugia malayi Carboxylesterase family protein 0.0069 0.0138 0.0524
Plasmodium falciparum plasmepsin X 0.0085 0.0183 0.0711
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0072 0.0267
Echinococcus granulosus adam 0.0034 0.0042 0.006
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0341 0.0883 0.3425
Schistosoma mansoni hypothetical protein 0.0146 0.0351 0.0813
Brugia malayi Calcitonin receptor-like protein seb-1 0.0463 0.1217 0.4723
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0096 0.0212 0.0814
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0044 0.0072 0.0072
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0075 0.0174
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0195 0.0484 0.187
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0085 0.0183 0.0424
Trypanosoma cruzi DNA repair protein, putative 0.0038 0.0054 0.0563
Leishmania major cytochrome p450-like protein 0.003 0.0033 0.0323
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.2166 0.5879 0.9171
Schistosoma mansoni hypothetical protein 0.1279 0.3452 0.8
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.006 0.0115 0.0115
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0005 0.0007
Mycobacterium ulcerans beta-lactamase 0.0106 0.024 0.3384
Echinococcus multilocularis cpg binding protein 0.0172 0.0419 0.0419
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Loa Loa (eye worm) RNA binding protein 0.0193 0.0478 0.1847
Loa Loa (eye worm) hypothetical protein 0.0096 0.0212 0.0814
Echinococcus granulosus microtubule associated protein 2 0.1595 0.4315 0.6182
Trypanosoma cruzi target of rapamycin kinase 3 0.005 0.0087 0.0941
Toxoplasma gondii aspartyl protease 0.0085 0.0183 0.0711
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.002 0.0005 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0036
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.006 0.0115 0.1262
Plasmodium falciparum ataxin-2 like protein, putative 0.008 0.0168 0.0654
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0005 0.0008
Echinococcus granulosus histone lysine methyltransferase setb 0.0125 0.0291 0.0417
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0042 0.0064 0.0064
Brugia malayi TAR-binding protein 0.0193 0.0478 0.1847
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0056 0.0102 0.0398
Brugia malayi MH2 domain containing protein 0.0029 0.0031 0.0108
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0092 0.02 0.0287
Giardia lamblia DINP protein human, muc B family 0.0044 0.0072 0.4076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0008 0.0031
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0072 0.0103
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0005 0.0005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0195 0.0484 0.1121
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0056 0.0103 0.039
Echinococcus multilocularis muscleblind protein 0.0232 0.0585 0.0585
Loa Loa (eye worm) aspartyl protease 6 0.0085 0.0183 0.07
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0193
Brugia malayi Smad1 0.0029 0.0031 0.0108
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.01
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0264 0.0673 0.2609
Plasmodium vivax thioredoxin reductase, putative 0.0161 0.039 0.1514
Loa Loa (eye worm) isocitrate dehydrogenase 0.006 0.0115 0.0436
Brugia malayi hypothetical protein 0.0085 0.0183 0.07
Echinococcus multilocularis polycomb protein SCMH1 0.0037 0.005 0.005
Schistosoma mansoni acetylcholinesterase 0.0069 0.0138 0.0319
Echinococcus granulosus dna polymerase kappa 0.0044 0.0072 0.0102
Echinococcus granulosus histone acetyltransferase MYST2 0.0042 0.0064 0.0092
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0341 0.0883 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0056 0.0102 0.0398
Echinococcus granulosus poly (ADP ribose) polymerase 0.0091 0.0198 0.0283
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0012 0.0083
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0958 0.2572 1
Echinococcus granulosus neuropeptide receptor A26 0.1396 0.3771 0.5402
Brugia malayi latrophilin 2 splice variant baaae 0.0316 0.0816 0.3164
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0103 0.0231 0.0231
Schistosoma mansoni poly [ADP-ribose] polymerase 0.016 0.0388 0.09
Echinococcus granulosus zinc finger protein Ran binding 0.0341 0.0883 0.1265
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0024
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0069 0.0138 0.0197
Echinococcus multilocularis SWI:SNF matrix associated 0.0958 0.2572 0.2572
Schistosoma mansoni myst-related protein 0.002 0.0006 0.0014
Onchocerca volvulus 0.0341 0.0883 0.3419
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0072 0.0882
Onchocerca volvulus 0.0106 0.024 0.0917
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0023 0.0012 0.0161
Schistosoma mansoni sex comb on midleg homolog 0.0037 0.005 0.0117
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0291 0.0748 1
Loa Loa (eye worm) kinesin-like protein KLP2 0.0066 0.0132 0.0501
Echinococcus multilocularis neuropeptide s receptor 0.1396 0.3771 0.3771
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0008 0.0031
Plasmodium falciparum plasmepsin VII 0.0085 0.0183 0.0711
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0269 0.0687 0.3218
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0048 0.0048
Echinococcus granulosus geminin 0.1279 0.3452 0.4945
Schistosoma mansoni kinesin eg-5 0.0066 0.0132 0.0305
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0089 0.0194 0.045
Onchocerca volvulus 0.0062 0.0119 0.0445
Schistosoma mansoni thyroid hormone receptor 0.002 0.0005 0.0011
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0005 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0031 0.0119
Trypanosoma cruzi hypothetical protein, conserved 0.0341 0.0883 1
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0063 0.0123 0.1639
Loa Loa (eye worm) hypothetical protein 0.0042 0.0064 0.0238
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0075 0.0156 0.071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0005 0.0008
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0138 0.0319
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0056 0.0102 0.112
Onchocerca volvulus 0.0958 0.2572 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0168
Echinococcus granulosus mixed lineage leukemia protein mll 0.0044 0.007 0.0101
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0066 0.0066
Entamoeba histolytica hypothetical protein 0.0103 0.0231 0.3085
Brugia malayi MH1 domain containing protein 0.0029 0.0031 0.0108
Brugia malayi isocitrate dehydrogenase 0.006 0.0115 0.0436
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0106 0.024 0.0924
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0341 0.0883 0.3432
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0005 0.0007
Echinococcus granulosus dna polymerase eta 0.0044 0.0072 0.0102
Brugia malayi YY1-associated factor 2 0.0341 0.0883 0.3425
Plasmodium falciparum ataxin-2 like protein, putative 0.008 0.0168 0.0654
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0033 0.0117
Echinococcus granulosus tumor protein p63 0.2568 0.698 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0063 0.0123 0.0466
Echinococcus granulosus adam 17 protease 0.0213 0.0533 0.0764
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0056 0.0102 0.0102
Mycobacterium ulcerans aldehyde dehydrogenase 0.0136 0.0321 0.4579
Trypanosoma cruzi WLM domain containing protein, putative 0.0341 0.0883 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0068 0.0265
Mycobacterium ulcerans recombinase A 0.0075 0.0156 0.213
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0078 0.0163 0.0623
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0005 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0291 0.0674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0168
Entamoeba histolytica kinesin, putative 0.0066 0.0132 0.1762
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0088 0.019 0.2545
Mycobacterium tuberculosis Conserved protein 0.0106 0.024 0.0367
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.0072 0.0278
Echinococcus granulosus acetylcholinesterase 0.0406 0.1061 0.1519
Echinococcus granulosus neuroligin 0.0069 0.0138 0.0197
Echinococcus multilocularis lamin dm0 0.0062 0.0119 0.0119
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0033 0.0312
Schistosoma mansoni lamin 0.0062 0.0119 0.0277
Echinococcus granulosus neuropeptide s receptor 0.1396 0.3771 0.5402
Schistosoma mansoni hypothetical protein 0.0257 0.0653 0.1514
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0063 0.0123 0.1342
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0478 0.1107
Leishmania major phosphatidylinositol 3-kinase, putative 0.0021 0.0008 0.0036
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.006 0.0115 0.0171
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0042 0.0064 0.0238
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.002 0.0005 0.0018
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0044 0.0072 0.0267
Loa Loa (eye worm) hypothetical protein 0.0341 0.0883 0.3425
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0102 0.1112
Echinococcus multilocularis tankyrase 0.0022 0.0009 0.0009
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0146 0.0351 0.1354
Schistosoma mansoni hypothetical protein 0.0078 0.0163 0.0378
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0008
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0054 0.0097 0.0097
Leishmania major trypanothione reductase 0.0161 0.039 0.4383
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0087 0.0339
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0029 0.0031 0.0295
Entamoeba histolytica heat shock transcription factor, putative 0.0069 0.0139 0.186
Echinococcus multilocularis carboxylesterase 5A 0.0406 0.1061 0.1061
Schistosoma mansoni lipoxygenase 0.0055 0.0102 0.0236
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0341 0.0883 0.3432
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0102 0.1339
Loa Loa (eye worm) hypothetical protein 0.0106 0.024 0.0924
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0068 0.0265
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0005 0.0007
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0082 0.0176 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0314 0.0809 0.3147
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.0031 0.0295
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0054 0.0097 0.0139
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0958 0.2572 1
Echinococcus granulosus acetylcholinesterase 0.0406 0.1061 0.1519
Trypanosoma brucei trypanothione reductase 0.0161 0.039 0.4388
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0069 0.0138 0.0138
Mycobacterium tuberculosis Conserved protein 0.0106 0.024 0.0367
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0085 0.0183 0.0424
Brugia malayi PHD-finger family protein 0.0032 0.0038 0.0136
Schistosoma mansoni cathepsin D (A01 family) 0.0475 0.1251 0.2899
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0138 0.0329 0.0763
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.006 0.0115 0.1254
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0136 0.0321 0.0493
Entamoeba histolytica heat shock transcription factor, putative 0.0069 0.0139 0.186
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0066 0.0094
Brugia malayi CXXC zinc finger family protein 0.0161 0.039 0.1508
Schistosoma mansoni terminal deoxycytidyl transferase 0.0044 0.0072 0.0166
Loa Loa (eye worm) Smad1 0.0029 0.0031 0.0108
Echinococcus granulosus beta LACTamase domain containing family member 0.0106 0.024 0.0344
Trypanosoma cruzi WLM domain containing protein, putative 0.0341 0.0883 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0406 0.1061 0.2458
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0195 0.0484 0.188
Schistosoma mansoni lamin 0.0062 0.0119 0.0277
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0063 0.0123 0.135
Loa Loa (eye worm) hypothetical protein 0.0203 0.0505 0.1955
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0341 0.0883 1
Schistosoma mansoni hypothetical protein 0.0958 0.2572 0.5962
Schistosoma mansoni hypothetical protein 0.0445 0.1167 0.2705
Loa Loa (eye worm) hypothetical protein 0.0037 0.005 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0005 0.0008
Plasmodium falciparum kinesin-5 0.0066 0.0132 0.0512
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0005 0.0007
Onchocerca volvulus 0.0376 0.0979 0.3794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0168
Loa Loa (eye worm) hypothetical protein 0.0032 0.0037 0.0131
Onchocerca volvulus Tankyrase homolog 0.0022 0.0009 0.0016
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.005 0.0193
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0056 0.0102 0.112
Entamoeba histolytica hypothetical protein 0.0103 0.0231 0.3085
Schistosoma mansoni nuclear hormone receptor 0.002 0.0005 0.0011
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0341 0.0883 0.1265
Loa Loa (eye worm) hypothetical protein 0.0316 0.0816 0.3164
Onchocerca volvulus 0.0062 0.0119 0.0445
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0193
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0029 0.0031 0.0071
Echinococcus multilocularis acetylcholinesterase 0.0406 0.1061 0.1061
Mycobacterium tuberculosis Probable oxidoreductase 0.0407 0.1065 0.1654
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0041 0.0062 0.023
Echinococcus multilocularis dna polymerase eta 0.0044 0.0072 0.0072
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0063 0.0123 0.1342
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0112 0.0112
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.006 0.0115 0.1254
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0195 0.0484 0.188
Echinococcus granulosus poly (ADP ribose) polymerase 0.0045 0.0074 0.0106
Schistosoma mansoni BC026374 protein (S09 family) 0.0069 0.0138 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0036
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.002 0.0005 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0102 0.1112
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.008 0.0168 0.0643
Toxoplasma gondii kinesin motor domain-containing protein 0.0066 0.0132 0.0512
Giardia lamblia NADH oxidase lateral transfer candidate 0.0056 0.0102 0.583
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0115 0.0264 0.1017
Onchocerca volvulus 0.0341 0.0883 0.3419
Echinococcus multilocularis geminin 0.1279 0.3452 0.3452
Brugia malayi hypothetical protein 0.0381 0.0994 0.3856
Brugia malayi intermediate filament protein 0.0062 0.0119 0.0453
Brugia malayi Importin beta-1 subunit 0.002 0.0004 0.0004
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0056 0.0102 0.1112
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0012 0.0093
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.005 0.0193
Brugia malayi mbt repeat family protein 0.0037 0.005 0.0184
Loa Loa (eye worm) hypothetical protein 0.0085 0.0183 0.07
Loa Loa (eye worm) hypothetical protein 0.016 0.0388 0.1499
Brugia malayi beta-lactamase family protein 0.0106 0.024 0.0924
Echinococcus multilocularis ubiquitin specific protease 41 0.0029 0.0031 0.0031
Trypanosoma brucei hypothetical protein, conserved 0.0106 0.024 0.269
Loa Loa (eye worm) hypothetical protein 0.0407 0.1065 0.4132
Brugia malayi Pre-SET motif family protein 0.0754 0.2015 0.7831
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0063 0.0123 0.1342
Echinococcus granulosus tar DNA binding protein 0.0193 0.0478 0.0684
Loa Loa (eye worm) hypothetical protein 0.0069 0.0138 0.0524
Toxoplasma gondii target of rapamycin (TOR), putative 0.0047 0.0078 0.0304
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0066 0.0245
Brugia malayi aspartic protease BmAsp-1, identical 0.0085 0.0183 0.07
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0463 0.1217 0.4723
Loa Loa (eye worm) hypothetical protein 0.0106 0.024 0.0924
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0005 0.0011
Trypanosoma brucei poly(adp-ribose) polymerase 0.016 0.0388 0.4372
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0958 0.2572 1
Toxoplasma gondii t-complex protein beta subunit 0.002 0.0005 0.0018
Schistosoma mansoni transcription factor LCR-F1 0.0103 0.0231 0.0535
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0102 0.1112
Loa Loa (eye worm) intermediate filament protein 0.0062 0.0119 0.0453
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0034 0.034
Plasmodium vivax kinesin-5 0.0066 0.0132 0.0512
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0082 0.0176 0.0682
Echinococcus granulosus L aminoadipate semialdehyde 0.0056 0.0103 0.0148
Mycobacterium tuberculosis Probable lipase LipE 0.0106 0.024 0.0367
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0056 0.0102 0.1339
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0193
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0063 0.0123 0.1639
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0036
Brugia malayi MH1 domain containing protein 0.0029 0.0031 0.0108
Schistosoma mansoni Smad4 0.0029 0.0031 0.0071
Toxoplasma gondii cathepsin CPC1 0.0082 0.0176 0.0682
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.002 0.0005 0.0005
Echinococcus multilocularis zinc finger protein Ran binding 0.0341 0.0883 0.0883
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0005 0.0005
Schistosoma mansoni bromodomain containing protein 0.0062 0.012 0.0277
Toxoplasma gondii isocitrate dehydrogenase 0.006 0.0115 0.0446
Leishmania major hypothetical protein, conserved 0.0341 0.0883 1
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0269 0.0687 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0102 0.1112
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0193
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0269 0.0687 1
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0075 0.0156 0.213
Schistosoma mansoni myst-related protein 0.002 0.0006 0.0014
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.006 0.0115 0.0165
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0072 0.0761
Trichomonas vaginalis helicase, putative 0.0036 0.005 0.0193
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0041 0.0062 0.023
Brugia malayi WGR domain containing protein 0.016 0.0388 0.1499
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0037 0.005 0.0176
Mycobacterium tuberculosis Probable reductase 0.0366 0.0953 0.1479
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0063 0.0123 0.135
Brugia malayi Inositol-1 0.0023 0.0012 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0082 0.0176 0.0682
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0075 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0008 0.0031
Trypanosoma brucei isocitrate dehydrogenase, putative 0.006 0.0115 0.1262
Echinococcus granulosus poly ADP ribose polymerase 1 0.0291 0.0748 0.1071
Echinococcus granulosus snurportin 1 0.021 0.0525 0.0753
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0005 0.0008
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0056 0.0102 0.1112
Plasmodium vivax ataxin-2 like protein, putative 0.008 0.0168 0.0654
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.0031 0.0119
Schistosoma mansoni hypothetical protein 0.1451 0.3923 0.9091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0078 0.0304
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0092 0.02 0.0769
Mycobacterium ulcerans aldehyde dehydrogenase 0.0136 0.0321 0.4579
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0102 0.1339
Plasmodium falciparum zinc finger protein, putative 0.002 0.0006 0.0023
Echinococcus multilocularis inositol monophosphatase 1 0.0023 0.0012 0.0012
Mycobacterium ulcerans hypothetical protein 0.0106 0.024 0.3384
Schistosoma mansoni survival motor neuron protein 0.0078 0.0163 0.0378
Echinococcus multilocularis BC026374 protein (S09 family) 0.0069 0.0138 0.0138
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.021 0.0525 0.2033
Schistosoma mansoni DNA polymerase eta 0.0044 0.0072 0.0166
Brugia malayi MH2 domain containing protein 0.0029 0.0031 0.0108
Echinococcus granulosus muscleblind protein 0.0232 0.0585 0.0838
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0366 0.0953 0.4475
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0106 0.024 0.0924
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.005 0.0193
Onchocerca volvulus Huntingtin homolog 0.0203 0.0505 0.1948
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0042 0.0064 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Loa Loa (eye worm) T-complex protein 1 0.002 0.0005 0.0007
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0005 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0005 0.0008
Schistosoma mansoni aldehyde dehydrogenase 0.0136 0.0321 0.0744
Schistosoma mansoni hypothetical protein 0.0036 0.0049 0.0114
Echinococcus multilocularis snurportin 1 0.021 0.0525 0.0525
Echinococcus granulosus lamin 0.0062 0.0119 0.0171
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0029 0.0031 0.0119
Echinococcus multilocularis importin subunit beta 1 0.002 0.0004 0.0004
Echinococcus granulosus carboxylesterase 5A 0.0406 0.1061 0.1519
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0029 0.0031 0.0031
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.016 0.0388 0.4367
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0005 0.0005
Onchocerca volvulus 0.0341 0.0883 0.3419
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0072 0.0267
Loa Loa (eye worm) hypothetical protein 0.0278 0.0711 0.2756
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0023 0.0012 0.0047
Echinococcus granulosus cpg binding protein 0.0172 0.0419 0.0601
Echinococcus granulosus lamin dm0 0.0062 0.0119 0.0171
Brugia malayi aspartic protease BmAsp-2, identical 0.0085 0.0183 0.07
Plasmodium falciparum plasmepsin VIII, putative 0.0085 0.0183 0.0711
Leishmania major hypothetical protein, conserved 0.0106 0.024 0.2683
Brugia malayi hypothetical protein 0.0069 0.0138 0.0524
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0009 0.0036
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0102 0.1112
Brugia malayi Isocitrate dehydrogenase 0.006 0.0115 0.0436
Echinococcus multilocularis expressed conserved protein 0.0082 0.0176 0.0176
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.002 0.0005 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0005 0.0008
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.006 0.0115 0.0446
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0005 0.0008
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0059 0.0231
Schistosoma mansoni hypothetical protein 0.0146 0.0351 0.0813
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0044 0.0072 0.0761
Trypanosoma brucei target of rapamycin kinase 3, putative 0.005 0.0087 0.095
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0005 0.0008
Loa Loa (eye worm) MBCTL1 0.0042 0.0064 0.0238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0406 0.1061 0.4116
Brugia malayi RNA, U transporter 1 0.0056 0.0103 0.0391
Trichomonas vaginalis spcc417.12 protein, putative 0.0069 0.0138 0.0535
Onchocerca volvulus 0.0111 0.0254 0.0972
Echinococcus granulosus GPCR family 2 0.0146 0.0351 0.0502
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0005 0.0011
Echinococcus granulosus inositol monophosphatase 1 0.0023 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0195 0.0484 0.187
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.003 0.0032 0.0315
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0072 0.0761
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.01
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0958 0.2572 1
Mycobacterium ulcerans esterase/lipase LipP 0.0106 0.024 0.3384
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0048 0.0069
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0005 0.0005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0146 0.0351 0.0502
Brugia malayi nuclear hormone receptor 0.002 0.0005 0.0008
Brugia malayi CHE-14 protein 0.0038 0.0053 0.0195
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.016 0.0388 0.0388
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0012 0.0047
Schistosoma mansoni zinc finger protein 0.0028 0.0026 0.0061
Brugia malayi Bromodomain containing protein 0.0033 0.0041 0.0149
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0072 0.077
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.016 0.0388 0.4367
Loa Loa (eye worm) hypothetical protein 0.0055 0.0101 0.0382
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0062 0.0119 0.0453
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0123 0.0476
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0008 0.0031
Schistosoma mansoni Replicative DNA helicase 0.0269 0.0687 0.1591
Onchocerca volvulus 0.0085 0.0183 0.0693
Loa Loa (eye worm) hypothetical protein 0.0376 0.0979 0.3799
Treponema pallidum replicative DNA helicase (dnaB) 0.0269 0.0687 1
Echinococcus granulosus FTZ F1 alpha 0.002 0.0005 0.0007
Schistosoma mansoni gliotactin 0.0069 0.0138 0.0319
Loa Loa (eye worm) MH2 domain-containing protein 0.0029 0.0031 0.0108
Loa Loa (eye worm) hypothetical protein 0.0069 0.0138 0.0524
Loa Loa (eye worm) MH2 domain-containing protein 0.0432 0.1133 0.4396
Loa Loa (eye worm) histone methyltransferase 0.0054 0.0097 0.0367
Entamoeba histolytica hypothetical protein 0.0045 0.0074 0.0988
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.005 0.0193
Trichomonas vaginalis chaperonin, putative 0.002 0.0005 0.0018
Mycobacterium tuberculosis Carboxylesterase LipT 0.0069 0.0138 0.0206
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0407 0.1065 0.5004
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0082 0.0176 0.0682
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0029 0.0031 0.0044
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0147 0.0353 0.0353
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.0031 0.0295
Schistosoma mansoni smad1 5 8 and 0.0029 0.0031 0.0071
Brugia malayi HSF-type DNA-binding domain containing protein 0.0069 0.0139 0.053
Onchocerca volvulus 0.0858 0.2299 0.8935
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0005 0.0005
Schistosoma mansoni smad 0.0029 0.0031 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0111 0.0254 0.059
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Loa Loa (eye worm) hypothetical protein 0.0106 0.024 0.0924
Trypanosoma brucei unspecified product 0.0044 0.0072 0.077
Onchocerca volvulus 0.0555 0.147 0.5707
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.006 0.0115 0.0115
Trypanosoma cruzi trypanothione reductase, putative 0.0056 0.0102 0.1112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0078 0.0304
Schistosoma mansoni cpg binding protein 0.0161 0.039 0.0905
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0052 0.0202
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0021 0.0008 0.0018
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0005 0.0008
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0012 0.0047
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0029 0.0031 0.0071
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0019 0.0003 0.0007
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0054 0.3063
Plasmodium falciparum T-complex protein 1 subunit beta 0.002 0.0005 0.0018
Plasmodium vivax aspartyl proteinase, putative 0.0085 0.0183 0.0711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0053 0.0206
Schistosoma mansoni zinc finger protein 0.0341 0.0883 0.2046
Brugia malayi hypothetical protein 0.0051 0.0091 0.0342
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0167
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0341 0.0883 0.3425
Onchocerca volvulus 0.0341 0.0883 0.3419
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0021 0.0008 0.0036
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.006 0.0115 0.0266
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0063 0.0123 0.1342
Echinococcus multilocularis microtubule associated protein 2 0.1595 0.4315 0.4315
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0044 0.007 0.007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0085 0.0183 0.0424
Echinococcus granulosus Smad4 0.0029 0.0031 0.0044
Brugia malayi Carboxylesterase family protein 0.0406 0.1061 0.4116
Echinococcus granulosus ring and YY1 binding protein 0.0341 0.0883 0.1265
Plasmodium falciparum thioredoxin reductase 0.0161 0.039 0.1514
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0291 0.0748 0.1732
Onchocerca volvulus DNA ligase 3 homolog 0.0038 0.0054 0.0192
Echinococcus multilocularis zinc finger protein 0.0028 0.0026 0.0026
Brugia malayi Pre-SET motif family protein 0.0111 0.0254 0.0979
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0078 0.0304
Schistosoma mansoni smad1 5 8 and 0.0029 0.0031 0.0071
Loa Loa (eye worm) hypothetical protein 0.0069 0.0138 0.0524
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0102 0.1112
Echinococcus multilocularis SWI:SNF matrix associated 0.0958 0.2572 0.2572
Brugia malayi RNA binding protein 0.0193 0.0478 0.1847
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0012 0.0083
Loa Loa (eye worm) hypothetical protein 0.0341 0.0883 0.3425
Entamoeba histolytica deoxycytidyl transferase, putative 0.0044 0.0072 0.0957
Trypanosoma brucei hypothetical protein, conserved 0.0341 0.0883 1
Onchocerca volvulus 0.0037 0.005 0.0176
Brugia malayi hypothetical protein 0.0103 0.0231 0.0886
Echinococcus multilocularis isocitrate dehydrogenase 0.006 0.0115 0.0115
Echinococcus granulosus zinc finger protein 0.0028 0.0026 0.0038
Schistosoma mansoni coup transcription factor 0.002 0.0005 0.0011
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0033 0.0323
Echinococcus multilocularis survival motor neuron protein 1 0.0381 0.0994 0.0994
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0146 0.0351 0.0502
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0068 0.0265
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.005 0.0193
Echinococcus multilocularis GPCR, family 2 0.0146 0.0351 0.0351
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0079 0.0167 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0078 0.0304
Schistosoma mansoni lipoxygenase 0.0079 0.0167 0.0387
Brugia malayi glutathione reductase 0.0161 0.039 0.1505
Loa Loa (eye worm) hypothetical protein 0.003 0.0032 0.0112
Echinococcus multilocularis mothers against decapentaplegic 5 0.0029 0.0031 0.0031
Onchocerca volvulus 0.0069 0.0138 0.0517
Echinococcus granulosus Niemann Pick C1 protein 0.0125 0.0293 0.042
Echinococcus granulosus BC026374 protein S09 family 0.0069 0.0138 0.0197
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0066 0.0245
Echinococcus multilocularis transcription factor eb 0.0096 0.0213 0.0213
Mycobacterium leprae Probable lipase LipE 0.0106 0.024 0.1109
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.002 0.0005 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0264 0.0673 0.0673
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0021 0.0008 0.0011
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0019 0.0003 0.0004
Echinococcus multilocularis acetylcholinesterase 0.0406 0.1061 0.1061
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0103 0.0231 0.033
Onchocerca volvulus 0.0161 0.039 0.1501
Loa Loa (eye worm) CYP4Cod1 0.003 0.0033 0.0117
Echinococcus granulosus intermediate filament protein 0.0062 0.0119 0.0171
Brugia malayi ecdysteroid receptor 0.002 0.0005 0.0008
Plasmodium falciparum plasmepsin IV 0.0195 0.0484 0.188
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0063 0.0123 0.0176
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0029 0.0031 0.0031
Schistosoma mansoni brg-1 associated factor 0.0958 0.2572 0.5962
Toxoplasma gondii isocitrate dehydrogenase 0.006 0.0115 0.0446
Loa Loa (eye worm) transcription factor SMAD2 0.0432 0.1133 0.4396
Brugia malayi hypothetical protein 0.0203 0.0505 0.1955
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0193
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0054 0.0719
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0068 0.0098
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0029 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0008
Brugia malayi Bromodomain containing protein 0.0071 0.0145 0.0552
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0136 0.0321 0.0321
Echinococcus granulosus polycomb protein SCMH1 0.0037 0.005 0.0072
Plasmodium falciparum glutathione reductase 0.0161 0.039 0.1514
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0024 0.0056
Loa Loa (eye worm) hypothetical protein 0.0341 0.0883 0.3425
Echinococcus multilocularis tar DNA binding protein 0.0193 0.0478 0.0478
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0038 0.0054 0.0563
Echinococcus granulosus kinesin family 1 0.0511 0.1349 0.1932
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0138 0.0319
Mycobacterium ulcerans carboxylesterase, LipT 0.0069 0.0138 0.1862
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0678 0.1805 0.2809
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0096 0.0213 0.0819
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0106 0.024 0.0367
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0059 0.0231
Onchocerca volvulus 0.0069 0.0138 0.0517
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0366 0.0953 0.1479
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0023 0.0033
Plasmodium vivax aspartyl protease, putative 0.0085 0.0183 0.0711
Echinococcus multilocularis neuroligin 0.0069 0.0138 0.0138
Schistosoma mansoni dihydroceramide desaturase 0.0019 0.0003 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0264 0.0673 0.0964
Schistosoma mansoni sex comb on midleg homolog 0.0037 0.005 0.0117
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0056 0.0103 0.0239
Echinococcus granulosus poly (ADP ribose) polymerase 0.0045 0.0074 0.0106
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0072 0.0882
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0019 0.0003 0.0003
Giardia lamblia TCP-1 chaperonin subunit beta 0.002 0.0005 0.0269
Plasmodium vivax plasmepsin V, putative 0.0085 0.0183 0.0711
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0082 0.0176 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0014
Brugia malayi Muscleblind-like protein 0.0232 0.0585 0.2265
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0044 0.007 0.007
Loa Loa (eye worm) carboxylesterase 0.0069 0.0138 0.0524
Schistosoma mansoni importin beta-1 0.002 0.0004 0.0009
Brugia malayi Carboxylesterase family protein 0.0069 0.0138 0.0524
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0054 0.0209
Echinococcus multilocularis adam 17 protease 0.0194 0.048 0.048
Toxoplasma gondii ran binding protein 0.0341 0.0883 0.3432
Schistosoma mansoni hypothetical protein 0.0958 0.2572 0.5962
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0264 0.0673 0.156
Plasmodium vivax glutathione reductase, putative 0.0161 0.039 0.1514
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0341 0.0883 1
Entamoeba histolytica hypothetical protein 0.0022 0.0009 0.0122
Mycobacterium tuberculosis Probable hydrolase 0.0106 0.024 0.0367
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0068 0.0265
Echinococcus multilocularis L aminoadipate semialdehyde 0.0056 0.0103 0.0103
Echinococcus granulosus poly adp ribose polymerase 2 0.016 0.0388 0.0556
Onchocerca volvulus 0.0106 0.024 0.0917
Brugia malayi Niemann-Pick C1 protein precursor 0.0088 0.019 0.0729
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0341 0.0883 0.3419
Echinococcus multilocularis beta LACTamase domain containing family member 0.0106 0.024 0.024
Echinococcus granulosus TGF beta signal transducer SmadC 0.0029 0.0031 0.0044
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0008 0.0019
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0958 0.2572 0.2572
Entamoeba histolytica hypothetical protein 0.002 0.0006 0.0081
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0092 0.02 0.02
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0112 0.016
Brugia malayi MH2 domain containing protein 0.0432 0.1133 0.4396
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0029 0.0031 0.0071
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0023 0.0023
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0106 0.024 0.0367
Giardia lamblia GTOR 0.0063 0.0123 0.6981
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0136 0.0321 0.3602
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.031 0.0798 0.31
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0341 0.0883 1
Trypanosoma cruzi PAB1-binding protein , putative 0.008 0.0168 0.1862
Leishmania major DNA polymerase eta, putative 0.0044 0.0072 0.0761
Loa Loa (eye worm) hypothetical protein 0.0069 0.0138 0.0524
Schistosoma mansoni hypothetical protein 0.0225 0.0567 0.1314
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0478 0.1107
Onchocerca volvulus 0.0056 0.0103 0.0382
Schistosoma mansoni hypothetical protein 0.0036 0.0048 0.0111
Echinococcus multilocularis muscleblind protein 1 0.0232 0.0585 0.0585
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0111 0.0254 0.059
Schistosoma mansoni smad1 5 8 and 0.0029 0.0031 0.0071
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.002 0.0005 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0087 0.0339
Trichomonas vaginalis inositol monophosphatase, putative 0.0023 0.0012 0.0047
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0056 0.0102 0.0398
Brugia malayi RNA recognition motif domain containing protein 0.0193 0.0478 0.1847
Brugia malayi nuclear receptor NHR-88 0.002 0.0005 0.0008
Echinococcus multilocularis kinesin family 1 0.0511 0.1349 0.1349
Loa Loa (eye worm) hypothetical protein 0.0406 0.1061 0.4116
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.002 0.0005 0.0018
Echinococcus granulosus mothers against decapentaplegic 5 0.0029 0.0031 0.0044
Brugia malayi Kinesin motor domain containing protein 0.0066 0.0132 0.0501
Entamoeba histolytica hypothetical protein 0.0022 0.0009 0.0122
Trypanosoma brucei unspecified product 0.0031 0.0034 0.034
Plasmodium falciparum plasmepsin III 0.0085 0.0183 0.0711
Brugia malayi Intermediate filament tail domain containing protein 0.0062 0.0119 0.0453
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0005 0.0007
Brugia malayi brahma associated protein 60 kDa 0.0958 0.2572 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.0072 0.0278
Toxoplasma gondii LsmAD domain-containing protein 0.008 0.0168 0.0654
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0005 0.0005
Loa Loa (eye worm) brahma associated protein 0.0958 0.2572 1
Plasmodium falciparum thioredoxin reductase 0.0056 0.0102 0.0398
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0038 0.0054 0.0572
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.006 0.0115 0.0115
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0034 0.0042 0.0098
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0958 0.2572 0.3685
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0005 0.0008
Brugia malayi Carboxylesterase family protein 0.0406 0.1061 0.4116
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0278 0.0711 0.275
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0056 0.0102 0.0398
Schistosoma mansoni cpg binding protein 0.0172 0.0419 0.0972
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0028 0.0027 0.0027
Echinococcus multilocularis neuropeptide receptor A26 0.1396 0.3771 0.3771
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0044 0.007 0.0101
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0072 0.077
Mycobacterium leprae conserved hypothetical protein 0.0106 0.024 0.1109
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0958 0.2572 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0053 0.0206
Brugia malayi hypothetical protein 0.0034 0.0042 0.0153
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0341 0.0883 0.3425
Plasmodium falciparum plasmepsin II 0.0195 0.0484 0.188
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0341 0.0883 1
Schistosoma mansoni cellular tumor antigen P53 0.0376 0.0979 0.2269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0123 0.0476
Leishmania major hypothetical protein, conserved 0.0341 0.0883 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0037 0.005 0.005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0161 0.039 0.1508
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.006 0.0115 0.1254
Loa Loa (eye worm) hypothetical protein 0.0106 0.024 0.0924
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.034 0.034
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0034 0.034
Loa Loa (eye worm) hypothetical protein 0.0232 0.0585 0.2265
Mycobacterium tuberculosis Conserved protein 0.0106 0.024 0.0367
Loa Loa (eye worm) hypothetical protein 0.0046 0.0076 0.0286
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0341 0.0883 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0754 0.2015 0.7831
Trypanosoma brucei hypothetical protein, conserved 0.0341 0.0883 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0005 0.0007
Onchocerca volvulus 0.0069 0.0138 0.0517
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0082 0.0176 0.0407
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Trypanosoma brucei cytochrome P450, putative 0.003 0.0033 0.0332
Echinococcus granulosus para nitrobenzyl esterase 0.0069 0.0138 0.0197
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.024 0.2683
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.024 0.0934
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0136 0.0321 0.046
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0341 0.0883 0.3425
Onchocerca volvulus 0.0078 0.0163 0.0615
Brugia malayi T-complex protein 1, beta subunit 0.002 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0463 0.1217 0.4723
Echinococcus multilocularis tumor protein p63 0.2568 0.698 0.698
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0111 0.0254 0.0989
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0005 0.0011
Schistosoma mansoni RNA binding protein 0.0341 0.0883 0.2046
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0008
Schistosoma mansoni neuroligin 3 (S09 family) 0.0069 0.0138 0.0319
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0066 0.0256
Brugia malayi beta-lactamase family protein 0.0106 0.024 0.0924
Trypanosoma cruzi hypothetical protein, conserved 0.0341 0.0883 1
Schistosoma mansoni hypothetical protein 0.0958 0.2572 0.5962
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Plasmodium vivax importin-beta 2, putative 0.002 0.0004 0.0015
Mycobacterium tuberculosis Probable esterase LipL 0.0106 0.024 0.0367
Leishmania major DNA repair protein, putative 0.0038 0.0054 0.0563
Leishmania major hypothetical protein, conserved 0.008 0.0168 0.1862
Schistosoma mansoni inositol monophosphatase 0.0023 0.0012 0.0028
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0345 0.0895 0.2074
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0044 0.0072 0.0166
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0085 0.0183 0.0424
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0106 0.024 0.3384
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.024 0.0557
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0102 0.112
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0106 0.024 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0167
Leishmania major DNA polymerase kappa, putative 0.0044 0.0072 0.0761
Echinococcus multilocularis protein patched 0.0038 0.0053 0.0053
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0023 0.0013 0.0107
Entamoeba histolytica hypothetical protein 0.0103 0.0231 0.3085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0097 0.0378
Schistosoma mansoni intermediate filament proteins 0.0062 0.0119 0.0277
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0407 0.1065 0.1654
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.024 0.0934
Loa Loa (eye worm) hypothetical protein 0.0088 0.019 0.0729
Brugia malayi Carboxylesterase family protein 0.0069 0.0138 0.0524
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0069 0.0138 0.0206
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0023 0.0054
Schistosoma mansoni fusion 0.0341 0.0883 0.2046
Toxoplasma gondii ABC1 family protein 0.0106 0.024 0.0934
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0033 0.0117
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.024 0.0557
Loa Loa (eye worm) hypothetical protein 0.0125 0.0291 0.1121
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0102 0.1112
Brugia malayi beta-lactamase 0.0106 0.024 0.0924
Plasmodium vivax aspartyl protease, putative 0.0085 0.0183 0.0711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0078 0.0304
Toxoplasma gondii thioredoxin reductase 0.0161 0.039 0.1514
Entamoeba histolytica hypothetical protein 0.0103 0.0231 0.3085
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0193 0.0478 0.1847
Loa Loa (eye worm) tnks protein 0.0022 0.0009 0.0024
Treponema pallidum recombinase A 0.0075 0.0156 0.0913
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.034 0.0788
Echinococcus granulosus Zinc finger RanBP2 type 0.0341 0.0883 0.1265
Trichomonas vaginalis hypothetical protein 0.002 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0106 0.024 0.0924
Echinococcus granulosus disintegrin and metalloproteinase 0.0019 0.0003 0.0004
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0029 0.0031 0.0304
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0085 0.0183 0.0424
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0056 0.0102 0.1339
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0087 0.0339
Trypanosoma brucei DNA repair protein, putative 0.0038 0.0054 0.0572
Toxoplasma gondii aspartyl protease ASP1 0.0195 0.0484 0.188
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0037 0.005 0.0117
Mycobacterium ulcerans aldehyde dehydrogenase 0.0136 0.0321 0.4579
Echinococcus multilocularis Niemann Pick C1 protein 0.0125 0.0293 0.0293
Echinococcus granulosus ubiquitin specific protease 41 0.0029 0.0031 0.0044
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0085 0.0183 0.0711
Echinococcus granulosus importin subunit beta 1 0.002 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0054 0.0199
Loa Loa (eye worm) hypothetical protein 0.0381 0.0994 0.3856
Brugia malayi steroid hormone receptor 0.002 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0102 0.1112
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.024 0.0934
Echinococcus multilocularis X box binding protein 1 0.0257 0.0653 0.0653
Loa Loa (eye worm) hypothetical protein 0.0069 0.0139 0.053
Loa Loa (eye worm) beta-lactamase 0.0106 0.024 0.0924
Toxoplasma gondii HEAT repeat-containing protein 0.002 0.0004 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.005 0.0193
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0005 0.0007
Echinococcus granulosus tankyrase 0.0022 0.0009 0.0013
Echinococcus multilocularis histone acetyltransferase MYST2 0.0042 0.0064 0.0064
Chlamydia trachomatis replicative DNA helicase 0.0269 0.0687 0.2366
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0005 0.0008
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0341 0.0883 0.0883
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0193
Schistosoma mansoni thyroid hormone receptor 0.002 0.0005 0.0011
Onchocerca volvulus 0.0085 0.0183 0.0693
Brugia malayi Pepsin A precursor 0.0085 0.0183 0.07
Onchocerca volvulus 0.0069 0.0138 0.0517
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0053 0.0206
Chlamydia trachomatis SWIB complex protein 0.0958 0.2572 1
Plasmodium vivax hypothetical protein, conserved 0.0958 0.2572 1
Plasmodium vivax plasmepsin IV, putative 0.0195 0.0484 0.188
Loa Loa (eye worm) TAR-binding protein 0.0193 0.0478 0.1847
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0366 0.0953 0.1479
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.003 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.005 0.0193
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0082 0.0176 0.0682
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0008 0.0019
Mycobacterium tuberculosis Probable lipase LipD 0.0106 0.024 0.0367
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0069 0.0138 0.0535
Toxoplasma gondii aspartyl protease ASP3 0.0085 0.0183 0.0711
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0026 0.0022 0.0202
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0067 0.0133 0.0133
Onchocerca volvulus Huntingtin homolog 0.0203 0.0505 0.1948
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0087 0.0339
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0125 0.0291 0.0291
Schistosoma mansoni hypothetical protein 0.0036 0.0049 0.0114
Echinococcus granulosus survival motor neuron protein 1 0.0381 0.0994 0.1424
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0146 0.0351 0.0351
Schistosoma mansoni hypothetical protein 0.0146 0.0351 0.0813
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0146 0.0351 0.0351
Trypanosoma cruzi hypothetical protein, conserved 0.0341 0.0883 1
Schistosoma mansoni hypothetical protein 0.0316 0.0816 0.1891
Loa Loa (eye worm) hypothetical protein 0.0222 0.0557 0.2157
Loa Loa (eye worm) inositol-1 0.0023 0.0012 0.0036
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.006 0.0115 0.0446
Giardia lamblia Kinesin-5 0.0066 0.0132 0.7504
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0043 0.0168
Loa Loa (eye worm) glutathione reductase 0.0161 0.039 0.1505
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0056 0.0102 0.0147
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0138 0.0319
Trypanosoma cruzi trypanothione reductase, putative 0.0161 0.039 0.4383
Echinococcus multilocularis thioredoxin glutathione reductase 0.0162 0.0393 0.0393
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0072 0.077
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0005 0.0008
Echinococcus multilocularis Niemann Pick C1 protein 0.0088 0.019 0.019
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0056 0.0102 0.1339
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0463 0.1217 0.4723
Schistosoma mansoni inositol monophosphatase 0.0023 0.0012 0.0028
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0102 0.112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0078 0.0304
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0079 0.0167 0.0167
Schistosoma mansoni hypothetical protein 0.1279 0.3452 0.8
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.005 0.0193
Echinococcus multilocularis Smad4 0.0029 0.0031 0.0031
Entamoeba histolytica zinc finger protein, putative 0.0022 0.0009 0.0122
Loa Loa (eye worm) latrophilin receptor protein 2 0.0146 0.0351 0.1354
Echinococcus granulosus SAM and MBT domain containing protein 0.0037 0.005 0.0072
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.007 0.0163

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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