Detailed information for compound 1635441

Basic information

Technical information
  • TDR Targets ID: 1635441
  • Name: S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydrox y-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyph osphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy- 3,3-dimethylbutanoyl]amino]propanoylamino]eth yl] 3-methylidenedodecanethioate
  • MW: 961.847 | Formula: C34H58N7O17P3S
  • H donors: 9 H acceptors: 15 LogP: -0.05 Rotable bonds: 32
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCCCCCC(=C)CC(=O)SCCNC(=O)CCNC(=O)C(C(COP(=O)(OP(=O)(OCC1OC(C(C1OP(=O)(O)O)O)n1cnc2c1ncnc2N)O)O)(C)C)O
  • InChi: 1S/C34H58N7O17P3S/c1-5-6-7-8-9-10-11-12-22(2)17-25(43)62-16-15-36-24(42)13-14-37-32(46)29(45)34(3,4)19-55-61(52,53)58-60(50,51)54-18-23-28(57-59(47,48)49)27(44)33(56-23)41-21-40-26-30(35)38-20-39-31(26)41/h20-21,23,27-29,33,44-45H,2,5-19H2,1,3-4H3,(H,36,42)(H,37,46)(H,50,51)(H,52,53)(H2,35,38,39)(H2,47,48,49)
  • InChiKey: RCLFDFMKMOJNRC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] 3-methylenedodecanethioate
  • 3-methylenedodecanethioic acid S-[2-[[3-[[4-[[[5-(6-amino-9-purinyl)-4-hydroxy-3-phosphonooxy-2-tetrahydrofuranyl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethyl-1-oxobutyl]amino]-1-oxopropyl]amino]ethyl] ester
  • 3-nonylbut-3-enethioic acid S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] ester
  • S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] 3-methylidenedodecanethioate
  • NCI60_010125

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi N-terminal motif family protein 0.002 0.0004 0.0003
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.002 0.0004 0.0004
Schistosoma mansoni serine/threonine-protein kinase 0.0073 0.0091 0.0091
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0051 0.0054 0.005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0162 0.0162
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0035 0.0029 0.0029
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0012 0.0011
Schistosoma mansoni bromodomain containing protein 0.0211 0.0315 0.0315
Trypanosoma cruzi DNA polymerase eta, putative 0.005 0.0052 0.0049
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0029 0.0018 0.0189
Loa Loa (eye worm) hypothetical protein 0.027 0.041 0.041
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.1165 0.1868 0.1868
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0397 0.0618 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.2065 0.3335 0.3332
Schistosoma mansoni hypothetical protein 0.0068 0.0081 0.0081
Onchocerca volvulus 0.0055 0.0061 0.0397
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Mycobacterium ulcerans lipase LipD 0.0074 0.0092 0.1919
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0057 0.0064 0.0061
Loa Loa (eye worm) phosphatidylinositol 3 0.2065 0.3335 0.3335
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0046 0.0046
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0118 0.0163 0.016
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0012 0.0128
Echinococcus granulosus zinc finger protein 0.0068 0.0082 0.0079
Leishmania major DNA polymerase eta, putative 0.005 0.0052 0.0049
Trypanosoma brucei rac serine-threonine kinase, putative 0.0106 0.0145 0.0141
Leishmania major phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0035 0.0029 0.0027
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0029 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0094 0.0124 0.0124
Brugia malayi follicle stimulating hormone receptor 0.0265 0.0403 0.0402
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.0043 0.004
Loa Loa (eye worm) hypothetical protein 0.0045 0.0045 0.0045
Brugia malayi protein kinase C II. 0.0035 0.0029 0.0028
Echinococcus multilocularis cation transporting ATPase 13A1 0.0029 0.0018 0.0015
Schistosoma mansoni immunophilin 0.0094 0.0124 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0092 0.0089
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Toxoplasma gondii exonuclease III APE 0.004 0.0036 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus granulosus protein kinase c epsilon type 0.0035 0.0029 0.0027
Trichomonas vaginalis cyclin B, putative 0.0057 0.0064 0.006
Brugia malayi Bromodomain containing protein 0.0249 0.0377 0.0376
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0035 0.0029 0.0026
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0397 0.0618 0.0618
Brugia malayi Pre-SET motif family protein 0.0232 0.035 0.0349
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0092 0.1195
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0029 0.0018 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0028 0.0028
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0036 0.1915
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.002 0.0004 0.0004
Onchocerca volvulus 0.0074 0.0092 0.0613
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0029 0.0018 0.0014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0265 0.0403 0.0403
Trichomonas vaginalis PIKK family atypical protein kinase 0.3325 0.5386 0.5385
Giardia lamblia Copper-transporting P-type ATPase 0.0029 0.0018 0.0014
Toxoplasma gondii FATC domain-containing protein 0.1165 0.1868 0.251
Plasmodium falciparum copper-transporting ATPase 0.0029 0.0018 0.0228
Leishmania major phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0397 0.0618 0.0618
Brugia malayi MH2 domain containing protein 0.0122 0.017 0.0169
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0051 0.0054 0.0052
Echinococcus granulosus hyperpolarization activated cyclic 0.003 0.002 0.0018
Loa Loa (eye worm) E1-E2 ATPase 0.0029 0.0018 0.0018
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0061 0.0061
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0232 0.0348 0.0348
Trypanosoma cruzi cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0092 0.009
Loa Loa (eye worm) thioredoxin reductase 0.0146 0.021 0.021
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Brugia malayi Protein kinase domain containing protein 0.0035 0.0029 0.0028
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0612
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0141 0.0201 0.0198
Echinococcus multilocularis serine protein kinase ATM 0.1165 0.1868 0.1866
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0397 0.0618 0.0615
Brugia malayi phosphofructokinase 0.0124 0.0173 0.0172
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0056 0.1127
Trichomonas vaginalis cyclin D, putative 0.0057 0.0064 0.006
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0334 0.0515 0.69
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0397 0.0618 1
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0397 0.0618 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0051 0.0054 1
Brugia malayi beta-lactamase family protein 0.0074 0.0092 0.0092
Echinococcus multilocularis Glutaredoxin protein 5 0.0064 0.0076 0.0073
Giardia lamblia Kinase, CMGC CDK 0.0048 0.005 0.0046
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0397 0.0618 0.0618
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.005 0.0047
Plasmodium vivax glutathione reductase, putative 0.0146 0.021 0.3351
Loa Loa (eye worm) hypothetical protein 0.0052 0.0056 0.0056
Entamoeba histolytica cyclin family protein 0.0057 0.0064 0.0058
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0006 0.0003
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0052 0.0056 0.1127
Brugia malayi glutaminase DH11.1 0.0303 0.0466 0.0465
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.003 0.002 0.0018
Trichomonas vaginalis cyclin B, putative 0.0083 0.0107 0.0103
Brugia malayi cell division control protein 2 homolog 0.0048 0.005 0.0049
Trichomonas vaginalis immunophilin, putative 0.0109 0.0149 0.0145
Brugia malayi hypothetical protein 0.0915 0.1461 0.1461
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0109 0.0149 0.0145
Entamoeba histolytica protein kinase, putative 0.0106 0.0145 0.0138
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.005 0.0046
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0012 0.0008
Trypanosoma brucei DNA polymerase eta, putative 0.005 0.0052 0.0049
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0036 0.0032
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1298 0.2085 0.2802
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0092 0.1195
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0092 0.1442
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0026 0.003
Loa Loa (eye worm) hypothetical protein 0.0133 0.0189 0.0189
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0029 0.0018 0.0019
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Toxoplasma gondii target of rapamycin (TOR), putative 0.4579 0.743 1
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.005 0.0047
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.002 0.0004 0.0004
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0006 0.0006
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0035 0.0029 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.413 0.6698 0.6697
Trichomonas vaginalis PIKK family atypical protein kinase 0.0397 0.0618 0.0615
Schistosoma mansoni ATPase 0.0029 0.0018 0.0018
Trichomonas vaginalis cyclins, putative 0.0083 0.0107 0.0103
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0029 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.002 0.0004 0.0004
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.005 0.0047
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.6157 1 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.003 0.0027
Echinococcus multilocularis thioredoxin glutathione reductase 0.0146 0.021 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.1298 0.2085 0.2082
Schistosoma mansoni phosphoserine phosphatase 0.0029 0.0018 0.0018
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1165 0.1868 0.1865
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0397 0.0618 0.0612
Schistosoma mansoni cpg binding protein 0.0073 0.009 0.009
Echinococcus granulosus microtubule associated protein 2 0.0764 0.1217 0.1214
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0397 0.0618 1
Echinococcus multilocularis geminin 0.1106 0.1772 0.177
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0029 0.0018 0.0303
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0036 0.0032
Echinococcus granulosus cGMP dependent protein kinase 0.0022 0.0008 0.0006
Schistosoma mansoni serine/threonine-protein kinase 0.0073 0.0091 0.0091
Plasmodium vivax P-type ATPase4, putative 0.0029 0.0018 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.3325 0.5386 0.5385
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0031 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Plasmodium vivax calcium-transporting ATPase, putative 0.0029 0.0018 0.0228
Plasmodium vivax copper-transporting ATPase, putative 0.0029 0.0018 0.0228
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0389 0.0604 0.0604
Echinococcus granulosus survival motor neuron protein 1 0.027 0.041 0.0408
Schistosoma mansoni cyclin B 0.0083 0.0107 0.0107
Schistosoma mansoni microtubule-associated protein tau 0.0764 0.1217 0.1217
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0026 0.002
Echinococcus multilocularis zinc finger protein 0.0068 0.0082 0.0079
Onchocerca volvulus 0.002 0.0004 0.0006
Mycobacterium ulcerans hypothetical protein 0.0052 0.0056 0.1127
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.0056 0.1127
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0029 0.0018 0.0303
Trichomonas vaginalis cyclins, putative 0.0057 0.0064 0.006
Plasmodium vivax protein kinase Crk2 0.0048 0.005 0.0743
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Leishmania major ATP-dependent phosphofructokinase 0.0124 0.0173 0.0169
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0092 0.0092
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0039 0.0036
Brugia malayi Cyclin, N-terminal domain containing protein 0.0057 0.0064 0.0063
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0022 0.0008 0.0005
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.2065 0.3335 0.3332
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0029 0.0018 0.0015
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0029 0.0018 0.0228
Entamoeba histolytica cyclin, putative 0.0057 0.0064 0.0058
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.002 0.0017
Echinococcus multilocularis Protein lozenge 0.0115 0.0158 0.0155
Toxoplasma gondii hypothetical protein 0.0053 0.0058 0.0073
Leishmania major phosphatidylinositol kinase related protein, putative 0.0397 0.0618 0.0615
Echinococcus granulosus histone lysine methyltransferase setb 0.009 0.0118 0.0116
Loa Loa (eye worm) jmjC domain-containing protein 0.0046 0.0046 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0118 0.0118
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Echinococcus granulosus NDR protein kinase 0.0035 0.0029 0.0027
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0056 0.005
Trichomonas vaginalis mercuric reductase, putative 0.0051 0.0054 0.005
Entamoeba histolytica cyclin family protein 0.0057 0.0064 0.0058
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0109 0.0149 0.0148
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0227 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.1652 0.2662 0.2659
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0028 0.0024
Echinococcus granulosus serine:threonine protein kinase N2 0.0035 0.0029 0.0027
Echinococcus granulosus serine threonine protein kinase nrc 0.0067 0.008 0.0078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0022 0.0008 0.0005
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0029 0.0018 0.0014
Schistosoma mansoni hypothetical protein 0.1106 0.1772 0.1772
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0118 0.0163 0.0161
Loa Loa (eye worm) glutathione reductase 0.0146 0.021 0.021
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0026 0.4378
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0029 0.0018 0.0014
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0051 0.0054 0.0816
Echinococcus granulosus cyclin B 0.0083 0.0107 0.0104
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0026 0.0357
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0061 0.0061
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.005 0.0046
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0094 0.0124 0.0122
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.6157 1 1
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0054 0.005
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0397 0.0618 0.0612
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Brugia malayi jmjC domain containing protein 0.0046 0.0046 0.0045
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Echinococcus granulosus voltage gated potassium channel 0.0044 0.0043 0.004
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0029 0.0018 0.0014
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0012 0.0008
Trichomonas vaginalis cyclin D, putative 0.0057 0.0064 0.006
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0397 0.0618 0.0615
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0397 0.0618 0.0615
Echinococcus multilocularis protein kinase c epsilon type 0.0035 0.0029 0.0026
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0092 0.1195
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0051 0.0054 0.005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0124 0.0173 0.2751
Trichomonas vaginalis AGC family protein kinase 0.0042 0.004 0.0036
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0026 0.1298
Echinococcus granulosus dna polymerase eta 0.005 0.0052 0.005
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0146 0.021 0.2779
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0031 0.003
Brugia malayi glutathione reductase 0.0146 0.021 0.0209
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0083 0.0107 0.0103
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0389 0.0604 0.0602
Schistosoma mansoni cation-transporting atpase worm 0.0029 0.0018 0.0018
Schistosoma mansoni cation-transporting atpase worm 0.0029 0.0018 0.0018
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0334 0.0515 0.69
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0151 0.0218 0.0218
Echinococcus granulosus cyclin B3 1 0.0057 0.0064 0.0061
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.6157 1 1
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0006 0.0052
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0397 0.0618 0.0616
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0056 0.0052
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0092 0.1195
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0397 0.0618 0.0616
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0073 0.007
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.4902 0.7956 0.7955
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0029 0.0018 0.0189
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0005 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0064 0.006
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.1165 0.1868 0.1866
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0397 0.0618 0.0615
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0109 0.0149 0.0145
Toxoplasma gondii hypothetical protein 0.0043 0.0041 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0397 0.0618 0.0616
Trichomonas vaginalis PIKK family atypical protein kinase 0.1165 0.1868 0.1865
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.002 0.0004 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0173 0.0169
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0094 0.0124 0.0121
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0029 0.0018 0.0015
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.003 0.002 0.0018
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0036 0.0036
Giardia lamblia PHD finger protein 15 0.003 0.002 0.0016
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0475 0.0745 1
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.005 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0397 0.0618 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.002 0.002
Echinococcus granulosus cyclin b3 0.0057 0.0064 0.0061
Echinococcus granulosus phospholipid transporting ATPase VA 0.0029 0.0018 0.0015
Echinococcus granulosus protein kinase C gamma type 0.0035 0.0029 0.0027
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0056 0.0052
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.005 0.0043
Echinococcus multilocularis peregrin 0.0038 0.0032 0.0029
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.002 0.0004 0.0004
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0092 0.1919
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0173 0.0167
Echinococcus granulosus cation transporting ATPase 13A1 0.0029 0.0018 0.0015
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0035 0.0029 0.0029
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0062 0.0073 0.0069
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0029 0.0018 0.0014
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0397 0.0618 0.0612
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0012 0.0128
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0035 0.0029 0.0029
Loa Loa (eye worm) glutaminase 0.0303 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Entamoeba histolytica protein kinase 2, putative 0.0067 0.008 0.0074
Plasmodium falciparum phd finger protein, putative 0.003 0.002 0.026
Trypanosoma cruzi copper-transporting ATPase, putative 0.0029 0.0018 0.0014
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0397 0.0618 1
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0036 0.0032
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0051 0.0054 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.3679 0.5964 0.5962
Schistosoma mansoni ATPase 0.0029 0.0018 0.0018
Giardia lamblia Kinase, AGC PKA 0.0067 0.008 0.0077
Loa Loa (eye worm) runx1 0.0115 0.0158 0.0158
Brugia malayi PHD-finger family protein 0.0085 0.011 0.0109
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0029 0.0025
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0057 0.0064 0.0061
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0051 0.0054 0.0067
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0109 0.0149 0.0145
Echinococcus multilocularis muscleblind protein 0.0498 0.0782 0.0779
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0051 0.0054 0.0676
Mycobacterium tuberculosis Probable oxidoreductase 0.0371 0.0576 0.7719
Schistosoma mansoni type V p-type atpase isoform 0.0029 0.0018 0.0018
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.013 0.0128
Schistosoma mansoni survival motor neuron protein 0.0055 0.0061 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Trichomonas vaginalis cyclin B, putative 0.0083 0.0107 0.0103
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0615
Echinococcus granulosus cyclic nucleotide gated cation channel 0.003 0.002 0.0018
Echinococcus multilocularis dna polymerase eta 0.005 0.0052 0.0049
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0006 0.0002
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.6157 1 1
Trichomonas vaginalis cyclin B, putative 0.0083 0.0107 0.0103
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0052 0.0056 0.0702
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0061 0.0061
Trypanosoma brucei trypanothione reductase 0.0146 0.021 0.0206
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0073 0.0073
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0173 0.0173
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.0043 0.004
Mycobacterium leprae Probable lipase LipE 0.0074 0.0092 0.1442
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0054 0.005
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0029 0.0018 0.0189
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0029 0.0018 0.0015
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0006 0.0003
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0067 0.008 0.0078
Treponema pallidum hypothetical protein 0.0029 0.0018 0.0828
Treponema pallidum cation-transporting ATPase, P-type 0.0029 0.0018 0.0828
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0397 0.0618 0.0616
Trypanosoma cruzi cyclin, putative 0.0083 0.0107 0.0103
Onchocerca volvulus 0.0074 0.0092 0.0613
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0397 0.0618 0.0615
Brugia malayi Hr1 repeat family protein 0.0035 0.0029 0.0028
Trichomonas vaginalis glutaminase, putative 0.0303 0.0466 0.0462
Loa Loa (eye worm) hypothetical protein 0.011 0.015 0.015
Trypanosoma brucei P-type H+-ATPase, putative 0.0029 0.0018 0.0014
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0036 0.0032
Echinococcus multilocularis expressed conserved protein 0.0022 0.0008 0.0005
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0051 0.0054 0.005
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0029 0.0025
Giardia lamblia NADH oxidase lateral transfer candidate 0.0051 0.0054 0.005
Leishmania major P-type H -ATPase, putative 0.0029 0.0018 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.332 0.5378 0.5376
Toxoplasma gondii thioredoxin reductase 0.0146 0.021 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.3325 0.5386 0.5385
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.005 0.0047
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.2065 0.3335 0.3333
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0018 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.1165 0.1868 0.1865
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Loa Loa (eye worm) hypothetical protein 0.0044 0.0043 0.0043
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0767 0.1221 0.1218
Trypanosoma brucei mitotic cyclin 6 0.0083 0.0107 0.0103
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0109 0.0149 0.0143
Trichomonas vaginalis cyclins, putative 0.0083 0.0107 0.0103
Schistosoma mansoni methyl-cpg binding protein mbd 0.0056 0.0062 0.0062
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0092 0.1442
Trypanosoma brucei P-type H+-ATPase, putative 0.0029 0.0018 0.0014
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0026 0.0022
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Toxoplasma gondii ABC1 family protein 0.0074 0.0092 0.0119
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0037 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0061
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0397 0.0618 1
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0039 0.0035 0.0413
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Trypanosoma brucei cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0035 0.0029 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0054 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0056 0.1127
Leishmania major peptidylprolyl isomerase-like protein 0.0109 0.0149 0.0145
Giardia lamblia GTOR 0.6157 1 1
Plasmodium falciparum thioredoxin reductase 0.0051 0.0054 0.0816
Trichomonas vaginalis cyclin A, putative 0.0083 0.0107 0.0103
Loa Loa (eye worm) hypothetical protein 0.0767 0.1221 0.1221
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0389 0.0604 0.0601
Echinococcus granulosus tumor protein p63 0.0751 0.1194 0.1192
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Echinococcus multilocularis cpg binding protein 0.0073 0.009 0.0087
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0173 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0006 0.0052
Echinococcus multilocularis rac serine:threonine kinase 0.0073 0.0091 0.0088
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0109 0.0149 0.0145
Echinococcus granulosus geminin 0.1106 0.1772 0.177
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0028 0.0028
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0051 0.0054 0.0054
Trichomonas vaginalis esterase, putative 0.0074 0.0092 0.0089
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0026 0.0357
Brugia malayi Melibiase family protein 0.0078 0.0098 0.0097
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0397 0.0618 0.0615
Echinococcus multilocularis hyperpolarization activated cyclic 0.003 0.002 0.0017
Mycobacterium leprae conserved hypothetical protein 0.0397 0.0618 1
Echinococcus granulosus lysine specific demethylase 5A 0.0046 0.0046 0.0044
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0029 0.0018 0.0015
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0173 0.0173
Echinococcus granulosus hyperpolarization activated cyclic 0.003 0.002 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Leishmania major DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus multilocularis voltage gated potassium channel 0.0044 0.0043 0.004
Loa Loa (eye worm) hypothetical protein 0.0915 0.1461 0.1461
Trichomonas vaginalis PIKK family atypical protein kinase 0.3679 0.5964 0.5962
Schistosoma mansoni immunophilin 0.0109 0.0149 0.0149
Plasmodium falciparum acyl-CoA synthetase 0.0039 0.0035 0.0499
Mycobacterium tuberculosis Conserved hypothetical protein 0.0397 0.0618 0.8291
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0073 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0008 0.0008
Leishmania major phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0615
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0389 0.0604 0.0604
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.003 0.002 0.002
Schistosoma mansoni hypothetical protein 0.005 0.0053 0.0053
Plasmodium vivax hypothetical protein, conserved 0.003 0.002 0.026
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0004 0.0001
Loa Loa (eye worm) phosphatidylinositol 3 0.6157 1 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0371 0.0576 0.7719
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.003 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0078 0.0098 0.0098
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Onchocerca volvulus 0.0029 0.0018 0.0102
Onchocerca volvulus 0.0166 0.0242 0.1636
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0026 0.003
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0033 0.0032
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0109 0.0149 0.0146
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0028 0.0033
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.002 0.0004 0.0001
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0026 0.003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0036 0.0527
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0389 0.0604 0.0604
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0012
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0029 0.0018 0.0014
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.002 0.002
Echinococcus multilocularis serine:threonine protein kinase 38 0.0035 0.0029 0.0026
Schistosoma mansoni hypothetical protein 0.0397 0.0618 0.0618
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0029 0.0018 0.0014
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0092 0.0092
Mycobacterium tuberculosis Probable dehydrogenase 0.0334 0.0515 0.69
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.1298 0.2085 0.2085
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0054 0.005
Schistosoma mansoni voltage-gated potassium channel 0.0165 0.024 0.024
Mycobacterium ulcerans hypothetical protein 0.0175 0.0256 0.5457
Schistosoma mansoni methyl-cpg binding protein mbd 0.0056 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.1255 0.2015 0.2015
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.09 0.1438 0.1435
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0092 0.0089
Loa Loa (eye worm) hypothetical protein 0.0498 0.0782 0.0782
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0037 0.0032 0.0031
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0092 0.1195
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0199 0.0296 0.0293
Schistosoma mansoni copper ABC transporter ATPase 0.0029 0.0018 0.0018
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.002 0.0021
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.1165 0.1868 0.1865
Trichomonas vaginalis PIKK family atypical protein kinase 0.3325 0.5386 0.5385
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0036 0.0527
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0029 0.0018 0.0015
Onchocerca volvulus 0.0074 0.0092 0.0613
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0124 0.0173 0.2281
Toxoplasma gondii NADPH-glutathione reductase 0.0051 0.0054 0.0067
Echinococcus multilocularis tumor protein p63 0.0751 0.1194 0.1191
Loa Loa (eye worm) AGC/PKG protein kinase 0.0022 0.0008 0.0008
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0092 0.0092
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0397 0.0618 0.0618
Trichomonas vaginalis PIKK family atypical protein kinase 0.5257 0.8534 0.8533
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0397 0.0618 0.0618
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0077 0.0097 0.0097
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0006 0.0002
Echinococcus multilocularis nervana 2 0.0064 0.0076 0.0073
Echinococcus granulosus thioredoxin glutathione reductase 0.0146 0.021 0.0207
Entamoeba histolytica protein kinase, putative 0.0106 0.0145 0.0138
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0092 0.0089
Entamoeba histolytica acyl-coA synthetase, putative 0.0052 0.0056 0.005
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0173 0.0169
Loa Loa (eye worm) hypothetical protein 0.0397 0.0618 0.0618
Trypanosoma cruzi proton motive ATPase 1, putative 0.0029 0.0018 0.0014
Trichomonas vaginalis cyclin B, putative 0.0083 0.0107 0.0103
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0006 0.0006
Schistosoma mansoni ap endonuclease 0.004 0.0036 0.0036
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0151 0.0218 0.0217
Echinococcus multilocularis fk506 binding protein 0.0109 0.0149 0.0146
Echinococcus granulosus patatin phospholipase domain containing protein 0.002 0.0004 0.0001
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0397 0.0618 0.0616
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0036 0.0701
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0173 0.0167
Loa Loa (eye worm) hypothetical protein 0.005 0.0052 0.0052
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.013 0.0127
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0092 0.0089
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0026 0.4378
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.002 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Plasmodium falciparum glutathione reductase 0.0051 0.0054 0.0816
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.2557 0.4137 0.4134
Mycobacterium ulcerans glutaminase 0.0303 0.0466 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Leishmania major copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.0131 0.0185 0.0185
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) beta-lactamase 0.0074 0.0092 0.0092
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0092 0.0089
Chlamydia trachomatis metal transport ATPase 0.0029 0.0018 0.2794
Entamoeba histolytica PH domain containing protein kinase, putative 0.0073 0.0091 0.0085
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0052 0.0056 0.1127
Echinococcus multilocularis 6 phosphofructokinase 0.0124 0.0173 0.017
Brugia malayi FAT domain containing protein 0.09 0.1438 0.1437
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0029 0.0018 0.0228
Loa Loa (eye worm) calcium ATPase 0.0029 0.0018 0.0018
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0029 0.0018 0.0019
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0006 0.0033
Loa Loa (eye worm) AGC/PKN protein kinase 0.0035 0.0029 0.0029
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0397 0.0618 0.0615
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.2065 0.3335 0.3332
Trypanosoma cruzi ISWI complex protein 0.005 0.0053 0.0049
Schistosoma mansoni cation-transporting ATPase 0.0029 0.0018 0.0018
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0029 0.0018 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.332 0.5378 0.5376
Plasmodium falciparum cyclin 0.0057 0.0064 0.0974
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0028 0.0032
Brugia malayi 6-phosphofructokinase 0.0124 0.0173 0.0172
Brugia malayi ImpB/MucB/SamB family protein 0.005 0.0052 0.0052
Schistosoma mansoni cyclins 0.0057 0.0064 0.0064
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0056 0.1127
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0012
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0078 0.0098 0.0094
Loa Loa (eye worm) glutaminase 2 0.0303 0.0466 0.0466
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0092 0.1919
Trichomonas vaginalis PIKK family atypical protein kinase 0.6157 1 1
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0035 0.0029 0.0026
Brugia malayi Bromodomain containing protein 0.0038 0.0032 0.0032
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.005 0.0043
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.002 0.0004 0.0004
Onchocerca volvulus 0.011 0.015 0.101
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.017 0.017
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0397 0.0618 0.0616
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0109 0.0149 0.8572
Onchocerca volvulus Alhambra homolog 0.003 0.002 0.0115
Trypanosoma cruzi Protein kinase B 0.0073 0.0091 0.0087
Loa Loa (eye worm) hypothetical protein 0.0143 0.0205 0.0205
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Trypanosoma cruzi target of rapamycin kinase 3 0.4902 0.7956 0.7955
Giardia lamblia Hypothetical protein 0.0397 0.0618 0.0615
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0066 0.0066
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0062 0.0073 0.0073
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0397 0.0618 0.0615
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0029 0.0018 0.0014
Schistosoma mansoni zinc finger protein 0.005 0.0053 0.0053
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus multilocularis 0.0397 0.0618 0.0616
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0006 0.0033
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.1165 0.1868 0.1863
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0018 0.0012
Leishmania major phosphatidylinositol 3-kinase, putative 0.2065 0.3335 0.3332
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0051 0.0054 0.005
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2065 0.3335 0.3332
Echinococcus multilocularis cyclin b3 0.0057 0.0064 0.0061
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.002 0.0004 0.0001
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0397 0.0618 0.0615
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0056 0.005
Loa Loa (eye worm) hypothetical protein 0.0083 0.0107 0.0107
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.005 0.0046
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0047 0.0043
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Toxoplasma gondii melibiase subfamily protein 0.0117 0.0162 0.0212
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.6157 1 1
Echinococcus granulosus Protein kinase C brain isozyme 0.0035 0.0029 0.0027
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0109 0.0149 0.2358
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.003 0.002 0.002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0334 0.0515 0.69
Leishmania major hypothetical protein, conserved 0.0025 0.0012 0.0008
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2065 0.3335 0.3334
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.3997 0.6482 0.648
Leishmania major hypothetical protein, conserved 0.0074 0.0092 0.0089
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Entamoeba histolytica hypothetical protein 0.1165 0.1868 0.1863
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0036 0.003
Plasmodium vivax hypothetical protein 0.0397 0.0618 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0073 0.1493
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.003 0.002 0.002
Trichomonas vaginalis cyclins, putative 0.004 0.0037 0.0033
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0615
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.2912 0.4714 0.4712
Brugia malayi Pre-SET motif family protein 0.0035 0.0028 0.0027
Echinococcus multilocularis cation transporting ATPase 13A3 0.0029 0.0018 0.0015
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0029 0.0018 0.0018
Mycobacterium tuberculosis Probable reductase 0.0334 0.0515 0.69
Trypanosoma cruzi CYC2-like cyclin, putative 0.0083 0.0107 0.0103
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0046 0.0046
Trypanosoma cruzi cyclin 6, putative 0.0083 0.0107 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0012 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0051 0.0054 0.1086
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0006 0.0006
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.005 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0173 0.0169
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.002 0.0004 0.0004
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.1165 0.1868 0.1868
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0397 0.0618 0.0616
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0029 0.0018 0.0303
Entamoeba histolytica cyclin, putative 0.0083 0.0107 0.0101
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0071 0.0071
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0067 0.008 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0008 0.0008
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0027 0.0015 0.0012
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0018 0.0001 0.0001
Schistosoma mansoni 60S ribosomal protein L21 0.0024 0.001 0.001
Echinococcus granulosus nervana 2 0.0064 0.0076 0.0074
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0029 0.0018 0.0228
Loa Loa (eye worm) hypothetical protein 0.0498 0.0782 0.0782
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0029 0.0018 0.0012
Loa Loa (eye worm) cyclin domain-containing protein 0.0057 0.0064 0.0064
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.001 0.001
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0124 0.0173 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0056 0.0062 0.006
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0035 0.0029 0.0027
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0026 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0389 0.0604 0.0604
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0109 0.0149 0.3139
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0006 0.0002
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.005 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0332 0.0511 0.0508
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0397 0.0618 0.0615
Brugia malayi hypothetical protein 0.0298 0.0456 0.0456
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0022 0.0008 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0397 0.0618 0.0615
Schistosoma mansoni vesicular amine transporter 0.0026 0.0014 0.0014
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.002 0.0004 0.0001
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0109 0.0149 0.0146
Brugia malayi beta-lactamase 0.0074 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0397 0.0618 0.0615
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0397 0.0618 0.0618
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0077 0.0097 0.0094
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0056 0.0062 0.0059
Brugia malayi hypothetical protein 0.027 0.041 0.041
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0043 0.0043
Echinococcus granulosus Glutaredoxin protein 5 0.0064 0.0076 0.0074
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.002 0.0016
Loa Loa (eye worm) phosphatidylinositol kinase 0.0397 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0005 0.0005
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0026 0.0357
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0051 0.0054 0.0816
Giardia lamblia Hypothetical protein 0.0057 0.0064 0.006
Trichomonas vaginalis cyclins, putative 0.0083 0.0107 0.0103
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0029 0.0018 0.0019
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0012
Schistosoma mansoni hypothetical protein 0.1106 0.1772 0.1772
Echinococcus granulosus cation transporting ATPase 13A3 0.0029 0.0018 0.0015
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0067 0.008 0.1246
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0039 0.0035 0.6115
Brugia malayi CXXC zinc finger family protein 0.0063 0.0073 0.0073
Echinococcus granulosus cyclin dependent kinase 6 0.018 0.0265 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.005 0.0046
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0109 0.0149 0.0145
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.005 0.005
Echinococcus multilocularis protein kinase c iota type 0.0035 0.0029 0.0026
Echinococcus multilocularis microtubule associated protein 2 0.0764 0.1217 0.1214
Brugia malayi PHD-finger family protein 0.002 0.0003 0.0002
Trypanosoma cruzi P-type H+-ATPase, putative 0.0029 0.0018 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0151 0.0218 0.0215
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.003 0.002 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Loa Loa (eye worm) hypothetical protein 0.09 0.1438 0.1438
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0397 0.0618 0.0618
Trichomonas vaginalis PIKK family atypical protein kinase 0.332 0.5378 0.5376
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0029 0.0018 0.0017
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0051 0.0054 0.0816
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0092 0.0089
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0004 0.0001
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0397 0.0618 0.0615
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0397 0.0618 0.0615
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0051 0.0054 0.1086
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0109 0.0149 0.0145
Loa Loa (eye worm) hypothetical protein 0.0915 0.1461 0.1461
Schistosoma mansoni atypical protein kinase C 0.0035 0.0029 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0035 0.0664
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0029 0.0018 0.0303
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0389 0.0604 0.0602
Leishmania major P-type H -ATPase, putative 0.0029 0.0018 0.0014
Brugia malayi beta-lactamase family protein 0.0074 0.0092 0.0092
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.002 0.0004 0.0001
Treponema pallidum NADH oxidase 0.0051 0.0054 0.2964
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0004 0.0004
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.005 0.0062
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.002 0.0021
Echinococcus granulosus serine:threonine protein kinase SMG1 0.1165 0.1868 0.1866
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0332 0.0511 0.0508
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0029 0.0018 0.0303
Plasmodium vivax acyl-CoA synthetase, putative 0.0039 0.0035 0.0499
Echinococcus multilocularis survival motor neuron protein 1 0.027 0.041 0.0408
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0056 0.0055
Schistosoma mansoni lozenge 0.0115 0.0158 0.0158
Leishmania major DNA polymerase eta, putative 0.0035 0.0028 0.0024
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0109 0.0149 0.0146
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0028 0.0025
Echinococcus granulosus copper transporting ATPase 1 0.0029 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0083 0.0107 0.0107
Onchocerca volvulus 0.0915 0.1461 1
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0029 0.0018 0.0014
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0157 0.0227 0.0223
Loa Loa (eye worm) hypothetical protein 0.0397 0.0618 0.0618
Entamoeba histolytica protein kinase, putative 0.01 0.0134 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.3643 0.5904 0.5903
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0067 0.008 0.1246
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0026 0.0357
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0006 0.0002
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0173 0.0173
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0029 0.0018 0.0017
Mycobacterium ulcerans 6-phosphofructokinase 0.0124 0.0173 0.3662
Plasmodium falciparum protein kinase 5 0.0048 0.005 0.0743
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0006 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0056 0.0702
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0044 0.0043 0.0042
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0062 0.0073 0.093
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0036 0.0032
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.2065 0.3335 0.3335
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0029 0.0018 0.0018
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0052 0.0056 0.1127
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0051 0.0054 0.0816
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Echinococcus granulosus cGMP dependent protein kinase 1 0.0022 0.0008 0.0006
Brugia malayi Cyclic-nucleotide gated cation channel 0.003 0.002 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0265 0.0265
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.09 0.1438 0.1436
Trichomonas vaginalis cyclins, putative 0.0083 0.0107 0.0103
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.2065 0.3335 0.3333
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0029 0.0018 0.0303
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0029 0.0018 0.0189
Echinococcus granulosus serine protein kinase ATM 0.1165 0.1868 0.1866
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.005 0.005
Echinococcus multilocularis cyclin dependent kinase 6 0.018 0.0265 0.0262
Echinococcus multilocularis serine:threonine protein kinase N2 0.0035 0.0029 0.0026
Schistosoma mansoni cpg binding protein 0.0063 0.0073 0.0073
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0061 0.006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0031 0.0367
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Trichomonas vaginalis fk506-binding protein, putative 0.0109 0.0149 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0767 0.1221 0.1218
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0092 0.1195
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.009 0.0118 0.0116
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0029 0.0018 0.0014
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0092 0.1195
Brugia malayi hypothetical protein 0.0025 0.0012 0.0011
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0173 0.0169
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Plasmodium falciparum cGMP-dependent protein kinase 0.0022 0.0008 0.0067
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.005 0.0046
Echinococcus granulosus 6 phosphofructokinase 0.0124 0.0173 0.0171
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.01 0.0134 0.0134
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0109 0.0149 0.0149
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0004 0.0001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0056 0.0846
Onchocerca volvulus 0.0264 0.0402 0.2735
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Mycobacterium tuberculosis Conserved hypothetical protein 0.0175 0.0256 0.3399
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0029 0.0018 0.0303
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.002 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Plasmodium vivax SET domain protein, putative 0.0035 0.0028 0.0385
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0035 0.0029 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0029 0.0018 0.0014
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0162 0.0162
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.002 0.0004 0.0003
Mycobacterium tuberculosis Conserved protein 0.0074 0.0092 0.1195
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0397 0.0618 0.0616
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0051 0.0054 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Leishmania major cyclin 0.0083 0.0107 0.0103
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0134 0.019 0.019
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.005 0.0046
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.002 0.0004 0.0001
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0029 0.0018 0.0017
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0141 0.0201 0.0198
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0397 0.0618 0.0616
Trichomonas vaginalis PIKK family atypical protein kinase 0.6157 1 1
Schistosoma mansoni cpg binding protein 0.0073 0.009 0.009
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0397 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Echinococcus multilocularis copper transporting ATPase 1 0.0029 0.0018 0.0015
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0005 0.0003
Onchocerca volvulus 0.0052 0.0056 0.0363
Trypanosoma brucei target of rapamycin kinase 3, putative 0.4902 0.7956 0.7955
Trypanosoma cruzi cyclin, putative 0.0083 0.0107 0.0103
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Entamoeba histolytica protein kinase, putative 0.0035 0.0029 0.0023
Brugia malayi Protein kinase domain containing protein 0.0106 0.0145 0.0144
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0162 0.0162
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.017 0.017
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0397 0.0618 0.0616
Schistosoma mansoni voltage-gated potassium channel 0.0165 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0126 0.0176 0.0176
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.6157 1 1
Echinococcus granulosus dna polymerase kappa 0.0021 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0298 0.0456 0.0456
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.002 0.002
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.002 0.0004 0.0004
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0035 0.0029 0.0029
Brugia malayi Thioredoxin reductase 0.0146 0.021 0.0209
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0035 0.0029 0.0026
Brugia malayi Cyclin, N-terminal domain containing protein 0.0083 0.0107 0.0106
Echinococcus granulosus cpg binding protein 0.0073 0.009 0.0087
Schistosoma mansoni cyclin B3 0.0057 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0064 0.006
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0029 0.0018 0.0014
Brugia malayi Muscleblind-like protein 0.0498 0.0782 0.0781
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.002 0.0004 0.0004
Loa Loa (eye worm) AGC/NDR protein kinase 0.0035 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0397 0.0618 0.0612
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0389 0.0604 0.0601
Brugia malayi Na,K-ATPase alpha subunit 0.0029 0.0018 0.0017
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0232 0.035 0.035
Loa Loa (eye worm) AGC/AKT protein kinase 0.0106 0.0145 0.0145
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0036 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Brugia malayi hypothetical protein 0.0029 0.0018 0.0017
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0051 0.0054 0.0053
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.6157 1 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Leishmania major proton motive ATPase, putative 0.0029 0.0018 0.0014
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0039 0.0036
Leishmania major trypanothione reductase 0.0146 0.021 0.0206
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0029 0.0018 0.0015
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.6157 1 1
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Trypanosoma cruzi trypanothione reductase, putative 0.0146 0.021 0.0206
Loa Loa (eye worm) PHD-finger family protein 0.0068 0.0081 0.0081
Trypanosoma brucei ISWI complex protein 0.005 0.0053 0.0049
Brugia malayi Cyclin, N-terminal domain containing protein 0.0083 0.0107 0.0106
Schistosoma mansoni glutaminase 0.0303 0.0466 0.0466
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0033 0.0025 0.0021
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0092 0.0092
Schistosoma mansoni similar to Protein C20orf152 homolog 0.002 0.0004 0.0004
Echinococcus granulosus cGMP dependent protein kinase 1 0.0022 0.0008 0.0006
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0371 0.0576 0.7719
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0397 0.0618 0.0615
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Loa Loa (eye worm) FKBP5 protein 0.0109 0.0149 0.0149
Brugia malayi hypothetical protein 0.0166 0.0242 0.0241
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0029 0.0018 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Leishmania major hypothetical protein, unknown function 0.0397 0.0618 0.0615
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0029 0.0018 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Brugia malayi Egg laying defective protein 4 0.0022 0.0008 0.0007
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0064 0.0076 0.0074
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.6157 1 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.003 0.002 0.0018
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0029 0.0018 0.0012
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0029 0.0018 0.0018
Toxoplasma gondii AGC kinase 0.01 0.0134 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Echinococcus multilocularis muscleblind protein 1 0.0498 0.0782 0.0779
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0097 0.0097
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0092 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.003 0.002 0.002
Echinococcus granulosus cation transporting atpase worm 0.0029 0.0018 0.0015
Entamoeba histolytica hypothetical protein 0.0397 0.0618 0.0612
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0397 0.0618 0.0616
Brugia malayi Bromodomain containing protein 0.0125 0.0176 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0036 0.0032
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Echinococcus multilocularis cation transporting atpase worm 0.0029 0.0018 0.0015
Echinococcus multilocularis serine:threonine protein kinase N2 0.0035 0.0029 0.0026
Onchocerca volvulus 0.0397 0.0618 0.422
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0227 0.0223
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0199 0.0296 0.0293
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0098 0.0098
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0056 0.0055
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0173 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0029 0.0018 0.0012
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0334 0.0515 0.8323
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0029 0.0018 0.0014
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0047 0.0043
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.005 0.0046
Echinococcus granulosus protein kinase c iota type 0.0035 0.0029 0.0027
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0389 0.0604 0.0604
Echinococcus multilocularis hyperpolarization activated cyclic 0.003 0.002 0.0017
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0109 0.0149 0.0145
Brugia malayi jmjC domain containing protein 0.0097 0.013 0.0129
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1165 0.1868 0.1865
Echinococcus granulosus cyclin dependent kinase 0.0048 0.005 0.0047
Leishmania major protein kinase, putative 0.0022 0.0008 0.0004
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.003 0.002 0.002
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0029 0.0018 0.0019
Brugia malayi Protein kinase domain containing protein 0.0035 0.0029 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0014
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0092 0.0089
Giardia lamblia Phosphatidylinositol 4-kinase 0.0397 0.0618 0.0615
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0151 0.0218 0.0215
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0073 0.007
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0036 0.0032
Giardia lamblia DINP protein human, muc B family 0.0021 0.0006 0.0002
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0029 0.0018 0.0015
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0012 0.0008
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0056 0.0846
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0117 0.0162 0.0159
Onchocerca volvulus 0.0035 0.0028 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.003 0.002 0.002
Onchocerca volvulus 0.0063 0.0073 0.0483
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0109 0.0149 0.0149
Leishmania major protein kinase, putative 0.0022 0.0008 0.0004
Mycobacterium tuberculosis Conserved protein 0.0074 0.0092 0.1195
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0117 0.0162 0.0159
Loa Loa (eye worm) bromodomain containing protein 0.0058 0.0066 0.0066
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0004 0.0004
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0067 0.008 0.0077
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0109 0.0149 0.2358
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0397 0.0618 0.0615
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0098 0.0098
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0397 0.0618 0.0616
Leishmania major hypothetical protein, conserved 0.005 0.0053 0.0049
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0003 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0031 0.0367
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0109 0.0149 0.0145
Loa Loa (eye worm) phosphofructokinase 0.0124 0.0173 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.3643 0.5904 0.5903
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0397 0.0618 0.0616
Echinococcus multilocularis nervana 2 0.0064 0.0076 0.0073
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0029 0.0018 0.0017
Echinococcus granulosus serine/threonine protein kinase 0.0073 0.0091 0.0089
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0043 0.0043
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0029 0.0018 0.0018
Echinococcus granulosus muscleblind protein 0.0498 0.0782 0.078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0767 0.1221 0.1218
Trichomonas vaginalis PIKK family atypical protein kinase 0.1165 0.1868 0.1865
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Plasmodium vivax thioredoxin reductase, putative 0.0146 0.021 0.3351
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0173 0.0169
Schistosoma mansoni serine/threonine kinase 0.0035 0.0029 0.0029
Toxoplasma gondii P-type ATPase4, putative 0.0029 0.0018 0.0019
Leishmania major mitochondrial DNA polymerase beta 0.0332 0.0511 0.0508
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.005 0.0046
Loa Loa (eye worm) hypothetical protein 0.009 0.0118 0.0118
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0397 0.0618 0.0616
Trypanosoma cruzi P-type H+-ATPase, putative 0.0029 0.0018 0.0014
Onchocerca volvulus 0.002 0.0004 0.0006
Plasmodium falciparum thioredoxin reductase 0.0146 0.021 0.3351
Giardia lamblia Cyclin A 0.0057 0.0064 0.006
Schistosoma mansoni fkbp-rapamycin associated protein 0.1165 0.1868 0.1868
Toxoplasma gondii P-type ATPase PMA1 0.0029 0.0018 0.0019
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0109 0.0149 0.0145
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.6157 1 1
Trichomonas vaginalis cyclin B3, putative 0.0057 0.0064 0.006
Entamoeba histolytica protein kinase rad3, putative 0.1165 0.1868 0.1863
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2065 0.3335 0.3332
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Echinococcus granulosus nervana 2 0.0064 0.0076 0.0074
Brugia malayi p70 ribosomal S6 kinase beta 0.01 0.0134 0.0133
Schistosoma mansoni DNA polymerase eta 0.005 0.0052 0.0052
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis set domain proteins, putative 0.0264 0.0402 0.0398
Trypanosoma cruzi ISWI complex protein 0.005 0.0053 0.0049
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0371 0.0576 0.9311
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0029 0.0018 0.0303
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0109 0.0149 0.0143
Toxoplasma gondii histone lysine methyltransferase SET1 0.0128 0.0179 0.0236
Entamoeba histolytica PH domain containing protein kinase, putative 0.0073 0.0091 0.0085
Plasmodium falciparum glutathione reductase 0.0146 0.021 0.3351
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0006 0.0004
Leishmania major fk506-binding protein 1-like protein 0.0109 0.0149 0.0145
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0109 0.0149 0.0145
Brugia malayi 6-phosphofructokinase 0.0124 0.0173 0.0172
Loa Loa (eye worm) hypothetical protein 0.0051 0.0054 0.0054
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.005 0.0046
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1165 0.1868 0.1868
Brugia malayi E1-E2 ATPase family protein 0.0029 0.0018 0.0017
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0332 0.0511 0.0508
Echinococcus multilocularis Zinc finger, PHD finger 0.0397 0.0618 0.0616
Echinococcus granulosus peregrin 0.0038 0.0032 0.003
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0109 0.0149 0.0148
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Toxoplasma gondii cation-transporting atpase family protein 0.0029 0.0018 0.0019
Trypanosoma brucei unspecified product 0.0021 0.0006 0.0002
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.003 0.002 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.005 0.005
Trichomonas vaginalis glutathione reductase, putative 0.0051 0.0054 0.005
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.002 0.0017
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0006 0.0006
Brugia malayi E1-E2 ATPase family protein 0.0029 0.0018 0.0017
Plasmodium vivax cation transporting ATPase, putative 0.0029 0.0018 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.09 0.1438 0.1434
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Echinococcus multilocularis serine threonine protein kinase 0.0035 0.0029 0.0026
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0397 0.0618 1
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0397 0.0618 0.0618
Giardia lamblia Kinase, CMGC CDK 0.0048 0.005 0.0046
Schistosoma mansoni zinc finger protein 0.0068 0.0082 0.0082
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0056 0.0055
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.005 0.0047
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0117 0.0162 0.0159
Onchocerca volvulus 0.0397 0.0618 0.422
Mycobacterium ulcerans hypothetical protein 0.0074 0.0092 0.1919
Loa Loa (eye worm) hypothetical protein 0.0166 0.0242 0.0242
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0031 0.0367
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.6157 1 1
Schistosoma mansoni cellular tumor antigen P53 0.011 0.015 0.015
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0173 0.0169
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0036 0.0437
Mycobacterium ulcerans beta-lactamase 0.0074 0.0092 0.1919
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0047 0.0043
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0051 0.0054 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0073 0.1493
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0047 0.0043
Leishmania major calcium-translocating P-type ATPase 0.0029 0.0018 0.0014
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0006 0.0002
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0052 0.0056 0.0056
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Loa Loa (eye worm) hypothetical protein 0.0052 0.0056 0.0056
Schistosoma mansoni atpase class VI type 11c 0.0029 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.002 0.0004 0.0004
Schistosoma mansoni immunophilin 0.0109 0.0149 0.0149
Schistosoma mansoni hypothetical protein 0.0055 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.09 0.1438 0.1438
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0397 0.0618 0.0615
Loa Loa (eye worm) PHD-finger family protein 0.003 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.6157 1 1
Echinococcus multilocularis cyclin B3 1 0.0057 0.0064 0.0061
Brugia malayi Protein kinase domain containing protein 0.0048 0.005 0.0049
Giardia lamblia G2/mitotic-specific cyclin B 0.0083 0.0107 0.0103
Brugia malayi PHD-finger family protein 0.003 0.002 0.0019
Leishmania major hypothetical protein, conserved 0.0397 0.0618 0.0615
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0036 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0092 0.0089
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.002 0.0004 0.0004
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0029 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0033
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0334 0.0515 0.69
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0029 0.0018 0.0019
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.002 0.002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1165 0.1868 0.1868
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0036 0.0033
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0023 0.0021
Schistosoma mansoni hypothetical protein 0.0038 0.0033 0.0033
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.005 0.0046
Mycobacterium tuberculosis Conserved protein 0.0074 0.0092 0.1195
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Echinococcus multilocularis patatin phospholipase domain containing protein 0.002 0.0004 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.3679 0.5964 0.5962
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0064 0.0076 0.0073
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0051 0.0054 0.1086
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Entamoeba histolytica hypothetical protein 0.0397 0.0618 0.0612
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0029 0.0018 0.0303
Schistosoma mansoni eyes absent homolog 0.0298 0.0456 0.0456
Loa Loa (eye worm) hypothetical protein 0.0298 0.0456 0.0456
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0054 0.005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0118 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0073 0.0091 0.0087
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.002 0.0004 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Onchocerca volvulus 0.0083 0.0107 0.0712
Echinococcus granulosus fetal alzheimer antigen falz 0.0077 0.0097 0.0095
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.002 0.0004 0.0001
Schistosoma mansoni ap endonuclease 0.004 0.0036 0.0036
Echinococcus multilocularis cyclin B 0.0083 0.0107 0.0104

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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