Detailed information for compound 1638628

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 500.59 | Formula: C27H25FN6OS
  • H donors: 3 H acceptors: 3 LogP: 5.01 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(Cn1ncc(c1)c1cnc(c2c1scc2c1ccc(cc1)NC(=O)Nc1cccc(c1)F)N)C
  • InChi: 1S/C27H25FN6OS/c1-16(2)13-34-14-18(11-31-34)22-12-30-26(29)24-23(15-36-25(22)24)17-6-8-20(9-7-17)32-27(35)33-21-5-3-4-19(28)10-21/h3-12,14-16H,13H2,1-2H3,(H2,29,30)(H2,32,33,35)
  • InChiKey: IAMWPQBDRXGGEF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aurora kinase B Starlite/ChEMBL References
Homo sapiens kinase insert domain receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Tyrosine kinase homolog Get druggable targets OG5_130320 All targets in OG5_130320
Echinococcus granulosus aurora kinase A Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium vivax serine/threonine protein kinase 6, putative Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium berghei serine/threonine protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica serine/threonine- protein kinase 6 , putative Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) AUR protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium knowlesi serine/threonine protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium yoelii putative protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Candida albicans likely protein kinase similar to S. cerevisiae IPL1 (YPL209C) Aurora protein kinase involved in regulating kinetochore-microtubu Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma brucei aurora B kinase Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma mansoni protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) AUR protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Toxoplasma gondii aurora kinase Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma cruzi aurora B kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase , putative Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania mexicana protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus multilocularis aurora kinase A Get druggable targets OG5_127024 All targets in OG5_127024
Trypanosoma congolense aurora B kinase Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica serine/threonine- protein kinase 6, putative Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania infantum protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Candida albicans likely protein kinase similar to S. cerevisiae IPL1 (YPL209C) Aurora protein kinase involved in regulating kinetochore-microtubu Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Brugia malayi serine/threonine kinase 12 Get druggable targets OG5_127024 All targets in OG5_127024
Cryptosporidium parvum protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Brugia malayi Immunoglobulin I-set domain containing protein Get druggable targets OG5_130320 All targets in OG5_130320
Giardia lamblia Aurora kinase Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus granulosus serine:threonine protein kinase 12 B Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica serine/threonine protein kinase 6, putative Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma japonicum ko:K08850 aurora kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Schistosoma japonicum Serine/threonine-protein kinase 12, putative Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) AUR protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania donovani Aurora I-related kinase Get druggable targets OG5_127024 All targets in OG5_127024
Plasmodium falciparum serine/threonine protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Loa Loa (eye worm) TK/KIN16 protein kinase Get druggable targets OG5_130320 All targets in OG5_130320
Trypanosoma brucei gambiense protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Neospora caninum hypothetical protein Get druggable targets OG5_127024 All targets in OG5_127024
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_127024 All targets in OG5_127024
Brugia malayi serine/threonine protein kinase 6 Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania major protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Cryptosporidium hominis protein kinase (EC 2.7.1.-) p46XlEg22 Get druggable targets OG5_127024 All targets in OG5_127024
Leishmania braziliensis protein kinase, putative Get druggable targets OG5_127024 All targets in OG5_127024
Brugia malayi serine/threonine-protein kinase 6 Get druggable targets OG5_127024 All targets in OG5_127024
Echinococcus multilocularis serine:threonine protein kinase 12 B Get druggable targets OG5_127024 All targets in OG5_127024
Onchocerca volvulus Get druggable targets OG5_130320 All targets in OG5_130320
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 aurora kinase B 303 aa 299 aa 22.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0216 0.1475 0.1566
Onchocerca volvulus 0.0051 0.0052 0.008
Toxoplasma gondii AGC kinase 0.0135 0.0777 0.2888
Loa Loa (eye worm) TK protein kinase 0.0145 0.0862 0.091
Leishmania major phosphatidylinositol 3-kinase, putative 0.005 0.0043 0.018
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0184 0.1198 0.4373
Schistosoma mansoni hypothetical protein 0.0108 0.0549 0.1059
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0204 0.0213
Entamoeba histolytica hypothetical protein 0.005 0.0049 0.0061
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0158 0.055
Onchocerca volvulus 0.0351 0.2638 0.5242
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0593 0.4722 0.4708
Schistosoma mansoni serine/threonine protein kinase 0.0472 0.3686 0.7105
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0274 0.0296
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0142 0.0837 0.0813
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Leishmania major protein kinase, putative 0.0078 0.0285 0.1185
Echinococcus granulosus raf serine:threonine protein kinase 0.0089 0.0385 0.0359
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Plasmodium falciparum casein kinase 1 0.013 0.0732 0.5868
Echinococcus multilocularis 0.0076 0.0275 0.0297
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.1046 0.3806
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0059 0.0122 0.0114
Loa Loa (eye worm) hypothetical protein 0.0222 0.1526 0.1621
Schistosoma mansoni diacylglycerol kinase theta 0.005 0.0049 0.0095
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0149 0.0896 0.0871
Brugia malayi STAT protein, DNA binding domain containing protein 0.0051 0.0052 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0117 0.0628 0.2246
Leishmania major protein kinase, putative 0.0184 0.1198 0.4982
Brugia malayi Cam kinase protein 1 0.012 0.0651 0.0684
Echinococcus multilocularis tyrosine protein kinase 0.0327 0.2432 0.2878
Schistosoma mansoni GTPase activating protein 0.0051 0.0052 0.0101
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0201 0.1345 0.1322
Trichomonas vaginalis AGC family protein kinase 0.0163 0.1017 0.3697
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.01 0.0474 0.1881
Schistosoma mansoni survival motor neuron protein 0.0108 0.0549 0.1059
Loa Loa (eye worm) SH2 domain-containing protein 0.0051 0.0052 0.0043
Echinococcus multilocularis netrin receptor unc 5 0.0052 0.0065 0.0046
Loa Loa (eye worm) hypothetical protein 0.0231 0.1605 0.1705
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0065 0.0174 0.0615
Plasmodium falciparum protein serine/threonine kinase-1 0.0184 0.1198 0.9743
Loa Loa (eye worm) CAMK/PKD protein kinase 0.021 0.1427 0.1515
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0091 0.0399 0.1565
Trichomonas vaginalis AGC family protein kinase 0.0174 0.1113 0.4058
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0142 0.0837 0.0883
Echinococcus multilocularis cyclin dependent kinase 0.0142 0.0837 0.097
Entamoeba histolytica diacylglycerol kinase, putative 0.005 0.0049 0.0061
Echinococcus granulosus dual specificity protein kinase clk2 0.0184 0.1198 0.1174
Loa Loa (eye worm) TK/EPH protein kinase 0.0137 0.0796 0.0839
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Echinococcus multilocularis protein kinase shaggy 0.0154 0.0939 0.1092
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0048 0.0028 0.0115
Brugia malayi Protein kinase domain containing protein 0.0196 0.1306 0.1385
Brugia malayi Immunoglobulin I-set domain containing protein 0.0057 0.0106 0.01
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0135 0.0777 0.0899
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0165 0.0514
Echinococcus multilocularis activin receptor type 0.0078 0.0285 0.0309
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1003 0.1934
Brugia malayi Ras association domain family 1 isoform A 0.005 0.0049 0.0039
Schistosoma mansoni growth factor receptor-bound protein 0.0082 0.032 0.0617
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0278 0.2014 0.1993
Plasmodium vivax tyrosine kinase-like protein, putative 0.0096 0.0446 0.3487
Loa Loa (eye worm) hypothetical protein 0.0052 0.0062 0.0053
Trichomonas vaginalis STE family protein kinase 0.006 0.0133 0.0394
Schistosoma mansoni protein kinase C mu 0.026 0.1859 0.3584
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0106 0.0533 0.2218
Echinococcus multilocularis roundabout 2 0.0059 0.0122 0.0114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Plasmodium falciparum NIMA related kinase 2 0.006 0.0133 0.0878
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0136 0.0789 0.0831
Echinococcus granulosus casein kinase I delta 0.013 0.0732 0.0708
Entamoeba histolytica PH domain containing protein kinase, putative 0.0196 0.1307 0.3634
Plasmodium falciparum calcium-dependent protein kinase 1 0.012 0.0651 0.5195
Schistosoma mansoni nck2/grb4 0.0079 0.0299 0.0577
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.012 0.0651 0.2332
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0644 0.2304
Entamoeba histolytica hypothetical protein 0.0076 0.0274 0.0699
Echinococcus granulosus twitchin 0.0143 0.0845 0.082
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.005 0.0043 0.0058
Schistosoma mansoni growth factor receptor-bound protein 0.0079 0.0299 0.0577
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.012 0.0651 0.5195
Echinococcus multilocularis tyrosine protein kinase Blk 0.0195 0.1298 0.1521
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0224 0.1545 0.1817
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0142 0.0837 0.0883
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0119 0.0644 0.5132
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0078 0.0285 0.0991
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.005 0.0043 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0799 0.2883
Schistosoma mansoni tensin 0.0051 0.0052 0.0101
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0135 0.0777 0.3156
Loa Loa (eye worm) TK/ROR protein kinase 0.0061 0.0146 0.0143
Echinococcus granulosus survival motor neuron protein 1 0.0531 0.4191 0.4175
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0537 0.1904
Echinococcus granulosus dual specificity 0.0166 0.1046 0.1022
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Loa Loa (eye worm) AGC/PKA protein kinase 0.0135 0.0777 0.0819
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.019 0.1254 0.5162
Brugia malayi protein kinase C3,putative 0.0188 0.1239 0.1314
Brugia malayi Protein kinase domain containing protein 0.0142 0.0837 0.0883
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0474 0.0915
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0166 0.1046 0.1107
Giardia lamblia Kinase, AGC PKA 0.0187 0.1228 0.4824
Echinococcus granulosus tyrosine protein kinase Src42A 0.0224 0.1545 0.1522
Loa Loa (eye worm) hypothetical protein 0.0081 0.0318 0.0327
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0563 0.2001
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0472 0.3686 0.3933
Loa Loa (eye worm) hypothetical protein 0.0217 0.1484 0.1576
Loa Loa (eye worm) hypothetical protein 0.0086 0.0359 0.0371
Loa Loa (eye worm) AUR protein kinase 0.0174 0.1113 0.1179
Schistosoma mansoni serine/threonine kinase 0.0201 0.1345 0.2594
Plasmodium falciparum glycogen synthase kinase 3 0.0154 0.0939 0.7592
Trypanosoma brucei polo-like protein kinase 0.0324 0.2404 0.8883
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0174 0.0335
Brugia malayi SH2 domain containing protein 0.009 0.0388 0.0402
Loa Loa (eye worm) hypothetical protein 0.0134 0.0772 0.0814
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0102 0.0498 0.0564
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.012 0.0651 0.0684
Trypanosoma cruzi cdc2-related kinase 3 0.0142 0.0837 0.3407
Schistosoma mansoni tyrosine kinase 0.0077 0.0276 0.0533
Plasmodium falciparum serine/threonine protein kinase KIN 0.0106 0.0533 0.421
Loa Loa (eye worm) hypothetical protein 0.0172 0.1094 0.1158
Giardia lamblia Kinase, CDC7 0.0107 0.0537 0.1778
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.1814 0.3497
Plasmodium falciparum casein kinase 2, alpha subunit 0.0119 0.0644 0.5132
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Schistosoma mansoni tyrosine kinase 0.0224 0.1545 0.2978
Echinococcus multilocularis casein kinase I delta 0.013 0.0732 0.0844
Schistosoma mansoni hypothetical protein 0.0068 0.0204 0.0394
Trypanosoma cruzi target of rapamycin kinase 3 0.0118 0.0629 0.2533
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0051 0.0052 0.0026
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0118 0.0629 0.225
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0146 0.0873 0.3159
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0101 0.0484 0.1297
Schistosoma mansoni protein kinase 0.0264 0.1893 0.365
Toxoplasma gondii NEK kinase 0.006 0.0133 0.0406
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0204 0.0206
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0276 0.1992 0.212
Brugia malayi protein-tyrosine kinase 0.0195 0.1298 0.1376
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.012 0.0651 0.0627
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0242 0.1704 0.1812
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1003 0.1934
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0196 0.1302 0.1381
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0097 0.0451 0.0508
Brugia malayi MH2 domain containing protein 0.0625 0.4998 0.5338
Echinococcus granulosus tyrosine kinase 0.0195 0.1298 0.1274
Loa Loa (eye worm) hypothetical protein 0.0059 0.0122 0.0117
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.005 0.0043 0.002
Echinococcus multilocularis protein kinase c epsilon type 0.0252 0.1791 0.2111
Loa Loa (eye worm) hypothetical protein 0.01 0.048 0.0501
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.072 0.5814 0.6213
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.153 0.295
Entamoeba histolytica casein kinase, putative 0.0119 0.0644 0.1751
Echinococcus granulosus Vam6:Vps39 protein 0.0104 0.0511 0.0486
Toxoplasma gondii AGC kinase 0.0135 0.0777 0.2888
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0142 0.0837 0.0883
Entamoeba histolytica PH domain containing protein kinase, putative 0.0144 0.0856 0.2353
Brugia malayi Protein kinase domain containing protein 0.0184 0.1198 0.1269
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.008 0.0305 0.0313
Brugia malayi Kinase associated domain 1 family protein 0.0122 0.067 0.0705
Echinococcus granulosus cyclin dependent kinase 5 0.0142 0.0837 0.0813
Echinococcus granulosus hypothetical protein 0.0051 0.0052 0.0026
Loa Loa (eye worm) TK protein kinase 0.0403 0.309 0.3296
Echinococcus granulosus aurora kinase A 0.0174 0.1113 0.1089
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.012 0.0651 0.0748
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0302 0.2215 0.2195
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0043 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0873 0.1683
Trypanosoma cruzi aurora B kinase, putative 0.0174 0.1113 0.4568
Echinococcus granulosus titin 0.008 0.0305 0.0279
Trichomonas vaginalis CAMK family protein kinase 0.0136 0.0789 0.2845
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0148 0.0889 0.3697
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.113 0.9351 1
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.1345 0.2594
Brugia malayi Protein kinase domain containing protein 0.0231 0.1603 0.1703
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0143 0.0844 0.0978
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0276 0.1992 0.2353
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.1046 0.2016
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0059 0.0122 0.0114
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.013 0.0732 0.0771
Echinococcus granulosus casein kinase i 0.013 0.0732 0.0708
Entamoeba histolytica protein kinase, putative 0.0154 0.0939 0.259
Echinococcus granulosus GPCR family 2 0.0068 0.0204 0.0178
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0101 0.0485 0.046
Loa Loa (eye worm) TK protein kinase 0.03 0.2196 0.2339
Echinococcus multilocularis mitogen activated protein kinase 11 0.019 0.1254 0.1469
Entamoeba histolytica protein kinase, putative 0.0076 0.0274 0.0699
Entamoeba histolytica protein kinase, putative 0.0102 0.0498 0.1337
Loa Loa (eye worm) variant SH3 domain-containing protein 0.005 0.0049 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0837 0.3027
Echinococcus multilocularis protein tyrosine kinase 0.0647 0.5187 0.6175
Brugia malayi Protein kinase domain containing protein 0.0125 0.0695 0.0731
Echinococcus multilocularis raf serine:threonine protein kinase 0.0089 0.0385 0.0428
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Entamoeba histolytica casein kinase, putative 0.013 0.0732 0.2002
Leishmania major serine/threonine-protein kinase a, putative 0.0048 0.0028 0.0115
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0324 0.2404 0.2561
Loa Loa (eye worm) hypothetical protein 0.0099 0.0468 0.0488
Brugia malayi Temporarily assigned gene name protein 59 0.0104 0.0511 0.0534
Entamoeba histolytica hypothetical protein 0.0076 0.0274 0.0699
Entamoeba histolytica protein kinase domain containing protein 0.0154 0.0939 0.259
Echinococcus multilocularis mitogen activated protein kinase 11 0.019 0.1254 0.1469
Leishmania major protein kinase, putative 0.0048 0.0028 0.0115
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Echinococcus multilocularis GPCR, family 2 0.0068 0.0204 0.0213
Brugia malayi diacylglycerol kinase 0.005 0.0049 0.0039
Brugia malayi Temporarily assigned gene name protein 59 0.0155 0.0951 0.1005
Trichomonas vaginalis CAMK family protein kinase 0.0324 0.2404 0.8883
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Loa Loa (eye worm) hypothetical protein 0.0143 0.0847 0.0894
Echinococcus multilocularis insulin receptor 0.0252 0.179 0.211
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.0388 0.0402
Echinococcus multilocularis growth factor receptor bound protein 2 0.0079 0.0299 0.0326
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0148 0.0889 0.3219
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0059 0.0122 0.0114
Schistosoma mansoni serine/threonine kinase 0.026 0.1853 0.3572
Schistosoma mansoni protein kinase 0.052 0.4096 0.7897
Onchocerca volvulus 0.0051 0.0052 0.008
Toxoplasma gondii histone kinase SNF1, putative 0.0106 0.0533 0.1947
Echinococcus granulosus tyrosine protein kinase shark 0.0346 0.2596 0.2577
Brugia malayi Casein kinase II, alpha chain 0.0119 0.0644 0.0676
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0777 0.1499
Schistosoma mansoni suppressor of cytokine signaling 0.0051 0.0052 0.0101
Echinococcus granulosus mitogen activated protein kinase 3 0.01 0.0474 0.0449
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.021 0.0767
Trichomonas vaginalis CK1 family protein kinase 0.013 0.0732 0.2634
Echinococcus granulosus protein kinase C gamma type 0.025 0.1769 0.1747
Echinococcus multilocularis protein kinase c eta type 0.005 0.0049 0.0027
Brugia malayi SH2 domain containing protein 0.0051 0.0052 0.0043
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0051 0.0052 0.0031
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0224 0.1545 0.1817
Schistosoma mansoni tensin 0.0051 0.0052 0.0101
Entamoeba histolytica cell division protein kinase 2, putative 0.0142 0.0837 0.23
Echinococcus multilocularis dual specificity protein kinase clk2 0.0184 0.1198 0.1401
Entamoeba histolytica hypothetical protein 0.0076 0.0274 0.0699
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.013 0.0732 0.0771
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0084 0.0341 0.0376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0377 0.1305
Schistosoma mansoni protein kinase 0.0076 0.0274 0.0528
Echinococcus multilocularis dual specificity 0.0166 0.1046 0.122
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0148 0.0889 0.3624
Loa Loa (eye worm) hypothetical protein 0.01 0.048 0.0501
Echinococcus granulosus serine:threonine protein kinase 0.0136 0.0789 0.0764
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0316 0.2342 0.2494
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0106 0.0533 0.2218
Brugia malayi Protein kinase domain containing protein 0.072 0.5814 0.6213
Entamoeba histolytica protein kinase domain containing protein 0.0242 0.1704 0.4763
Leishmania major protein kinase A catalytic subunit 0.0135 0.0777 0.3234
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0201 0.1345 0.1322
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0324 0.2404 0.2384
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0135 0.0777 0.0899
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0302 0.2215 0.2619
Loa Loa (eye worm) hypothetical protein 0.0415 0.319 0.3403
Brugia malayi serine/threonine kinase 12 0.0174 0.1113 0.1179
Entamoeba histolytica serine/threonine protein kinase, putative 0.006 0.0133 0.03
Echinococcus multilocularis myotubularin protein 13 0.0059 0.0127 0.0121
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0135 0.0777 0.3156
Trypanosoma cruzi NIMA-related kinase, putative 0.006 0.0133 0.0444
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0266 0.1907 0.1885
Loa Loa (eye worm) hypothetical protein 0.012 0.0651 0.0684
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.019 0.1254 0.5162
Schistosoma mansoni protein kinase 0.0276 0.1992 0.3841
Brugia malayi Protein kinase domain containing protein 0.026 0.1853 0.1971
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.01 0.0474 0.0495
Entamoeba histolytica protein kinase domain containing protein 0.0119 0.0644 0.1751
Brugia malayi ribosomal protein S6 kinase alpha 3 0.014 0.0819 0.0864
Entamoeba histolytica protein kinase domain containing protein 0.0146 0.0873 0.2401
Trichomonas vaginalis PIKK family atypical protein kinase 0.0117 0.0628 0.2246
Echinococcus multilocularis mitogen activated protein kinase 0.01 0.0474 0.0536
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.019 0.1254 0.5218
Trypanosoma cruzi Protein kinase B 0.0196 0.1307 0.5383
Echinococcus multilocularis twitchin 0.0061 0.0143 0.0139
Trichomonas vaginalis AGC family protein kinase 0.0174 0.1113 0.4058
Onchocerca volvulus 0.0231 0.1605 0.3178
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.012 0.0651 0.0627
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.006 0.0133 0.0878
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0096 0.0445 0.0419
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0101 0.0484 0.1921
Loa Loa (eye worm) hypothetical protein 0.0121 0.0662 0.0695
Trypanosoma brucei aurora B kinase 0.0174 0.1113 0.4058
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1003 0.1934
Brugia malayi SH2 domain containing protein 0.0454 0.3526 0.3762
Schistosoma mansoni protein kinase 0.0183 0.1192 0.2299
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0224 0.1545 0.1522
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.024 0.1685 0.1791
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0533 0.1028
Echinococcus multilocularis Rac GTPase activating protein 1 0.005 0.0049 0.0027
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0135 0.0777 0.3156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0369 0.1277
Loa Loa (eye worm) hypothetical protein 0.0081 0.0318 0.0327
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0734 0.5938 0.7074
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0174 0.1113 0.3084
Leishmania major protein kinase A catalytic subunit isoform 2 0.0135 0.0777 0.3234
Trypanosoma brucei casein kinase I, isoform 2 0.013 0.0732 0.2634
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0195 0.1298 0.1274
Echinococcus multilocularis Protein kinase C, brain isozyme 0.03 0.2201 0.2602
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0644 0.2304
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0051 0.0052 0.0043
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.019 0.1254 0.4585
Schistosoma mansoni vam6/vps39 related 0.0104 0.0511 0.0986
Loa Loa (eye worm) hypothetical protein 0.0628 0.5022 0.5365
Brugia malayi Protein kinase domain containing protein 0.0099 0.0468 0.0488
Schistosoma mansoni tyrosine kinase 0.0205 0.1385 0.2671
Brugia malayi Serine/threonine-protein kinase SULU 0.0266 0.1907 0.2029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0117 0.0628 0.2246
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0061 0.0146 0.0119
Echinococcus granulosus tyrosine protein kinase 0.0327 0.2432 0.2412
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0216 0.1475 0.1566
Loa Loa (eye worm) hypothetical protein 0.009 0.0388 0.0402
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0065 0.0174 0.0173
Echinococcus granulosus protein kinase c epsilon type 0.0252 0.1791 0.1769
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.1046 0.3806
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Entamoeba histolytica protein kinase, putative 0.0097 0.0451 0.1203
Loa Loa (eye worm) TK protein kinase 0.0327 0.2432 0.2591
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0104 0.0511 0.0486
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0939 0.3408
Trypanosoma brucei NIMA-related protein kinase 0.006 0.0133 0.0394
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.012 0.0651 0.2402
Schistosoma mansoni nephrin 0.0123 0.0674 0.1299
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Echinococcus granulosus tyrosine protein kinase Fyn 0.0224 0.1545 0.1522
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0097 0.0451 0.0426
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0187 0.1228 1
Plasmodium vivax protein kinase Crk2 0.0142 0.0837 0.6742
Trichomonas vaginalis STE family protein kinase 0.0076 0.0274 0.092
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0079 0.0299 0.0307
Loa Loa (eye worm) hypothetical protein 0.0111 0.0573 0.0601
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0222 0.153 0.1507
Schistosoma mansoni cell adhesion molecule 0.0059 0.0122 0.0235
Brugia malayi protein kinase C II. 0.0252 0.1791 0.1905
Echinococcus multilocularis casein kinase i 0.013 0.0732 0.0844
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0101 0.0484 0.1921
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.021 0.0767
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.006 0.0133 0.0444
Echinococcus granulosus casein kinase I alpha 0.013 0.0732 0.0708
Schistosoma mansoni protein kinase 0.052 0.4096 0.7897
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0222 0.153 0.1625
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.2404 0.4634
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0264 0.1893 0.1872
Brugia malayi hypothetical protein 0.0628 0.5022 0.5365
Plasmodium falciparum cGMP-dependent protein kinase 0.0161 0.1001 0.8102
Loa Loa (eye worm) SH2 domain-containing protein 0.0051 0.0052 0.0043
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0166 0.1046 0.4285
Brugia malayi SH2 domain containing protein 0.0051 0.0052 0.0043
Schistosoma mansoni rap gtpase-activating protein 0.0104 0.0511 0.0986
Leishmania major protein kinase, putative 0.006 0.0133 0.0553
Plasmodium vivax calcium-dependent protein kinase, putative 0.012 0.0651 0.5195
Echinococcus multilocularis hypothetical protein 0.0122 0.067 0.077
Leishmania major cathepsin L-like protease 0.0069 0.021 0.0873
Echinococcus multilocularis dual specificity 0.0146 0.0873 0.1013
Echinococcus multilocularis tumor protein p63 0.0759 0.6153 0.7331
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0837 0.1614
Loa Loa (eye worm) AGC/AKT protein kinase 0.0358 0.2703 0.2881
Echinococcus multilocularis casein kinase I alpha 0.013 0.0732 0.0844
Onchocerca volvulus Serine\/threonine kinase homolog 0.0196 0.1306 0.2581
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0104 0.0511 0.0986
Echinococcus granulosus Rac GTPase activating protein 1 0.005 0.0049 0.0023
Entamoeba histolytica PH domain containing protein kinase, putative 0.0196 0.1307 0.3634
Trypanosoma cruzi casein kinase, putative 0.013 0.0732 0.2966
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0264 0.1893 0.2234
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0422 0.3255 0.3863
Onchocerca volvulus 0.0052 0.0062 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.1046 0.3806
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0277 0.2003 0.2365
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0196 0.1306 0.1282
Echinococcus multilocularis ephrin type A receptor 4 A 0.0116 0.0614 0.0703
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0099 0.0468 0.1646
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0777 0.1499
Trichomonas vaginalis AGC family protein kinase 0.0358 0.2703 1
Brugia malayi Fibronectin type III domain containing protein 0.01 0.048 0.0501
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0537 0.1904
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0538 0.4248 0.4535
Brugia malayi Variant SH3 domain containing protein 0.0079 0.0299 0.0307
Entamoeba histolytica protein kinase , putative 0.0174 0.1113 0.3084
Brugia malayi phosphoinositide-dependent protein kinase I 0.0097 0.0451 0.047
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0101 0.0484 0.1297
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0732 0.1412
Brugia malayi Immunoglobulin I-set domain containing protein 0.01 0.048 0.0501
Loa Loa (eye worm) protein kinase domain-containing protein 0.0255 0.1814 0.1929
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0474 0.1671
Trichomonas vaginalis CAMK family protein kinase 0.0324 0.2404 0.8883
Entamoeba histolytica protein kinase, putative 0.0174 0.1113 0.3084
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.012 0.0651 0.2402
Echinococcus multilocularis myosin iiia 0.0101 0.0484 0.0547
Echinococcus granulosus casein kinase I gamma 0.0255 0.1814 0.1792
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0102 0.0498 0.0564
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0122 0.0117
Onchocerca volvulus Serine\/threonine kinase homolog 0.0324 0.2404 0.4774
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0377 0.1305
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Entamoeba histolytica protein kinase 2, putative 0.0187 0.1228 0.3412
Leishmania major protein kinase, putative 0.0174 0.1113 0.4631
Echinococcus granulosus nervana 2 0.0149 0.0896 0.0871
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0303 0.1031
Trichomonas vaginalis CMGC family protein kinase 0.0184 0.1198 0.4373
Schistosoma mansoni cell adhesion molecule 0.0059 0.0122 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0303 0.1031
Plasmodium falciparum calcium-dependent protein kinase 5 0.012 0.0651 0.5195
Entamoeba histolytica protein kinase, putative 0.0084 0.0341 0.0891
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0251 0.1778 0.1756
Giardia lamblia Kinase, PLK 0.0324 0.2404 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Loa Loa (eye worm) CAMK/PKD protein kinase 0.026 0.1859 0.1978
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0051 0.0052 0.0031
Echinococcus granulosus NDR protein kinase 0.0201 0.1345 0.1322
Loa Loa (eye worm) hypothetical protein 0.01 0.048 0.0501
Trichomonas vaginalis STE family protein kinase 0.0102 0.0498 0.1759
Schistosoma mansoni serine/threonine protein kinase 0.0422 0.3255 0.6275
Trichomonas vaginalis PIKK family atypical protein kinase 0.0088 0.0377 0.1305
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0057 0.0106 0.01
Entamoeba histolytica protein kinase, putative 0.0166 0.1046 0.2893
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0063 0.0161 0.0498
Plasmodium falciparum calcium-dependent protein kinase 4 0.012 0.0651 0.5195
Schistosoma mansoni hypothetical protein 0.0068 0.0204 0.0394
Echinococcus granulosus SH2 domain containing protein 7 0.0051 0.0052 0.0026
Brugia malayi ephrin receptor 1 precursor 0.0075 0.0264 0.027
Echinococcus granulosus SH2 motif 0.0051 0.0052 0.0026
Schistosoma mansoni protein kinase 0.0102 0.0498 0.096
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0174 0.1113 0.904
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0063 0.0161 0.0498
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.0889 0.3219
Echinococcus multilocularis rac serine:threonine kinase 0.0196 0.1307 0.1532
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0059 0.0122 0.0096
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0118 0.0629 0.2619
Schistosoma mansoni neuroglian 0.0059 0.0122 0.0235
Loa Loa (eye worm) RasGEF domain-containing protein 0.005 0.0049 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0133 0.0394
Trypanosoma cruzi casein kinase, delta isoform, putative 0.013 0.0732 0.2966
Echinococcus granulosus tumor protein p63 0.0759 0.6153 0.6142
Schistosoma mansoni cell adhesion molecule 0.0118 0.063 0.1214
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0184 0.1198 0.4505
Trichomonas vaginalis PIKK family atypical protein kinase 0.0117 0.0628 0.2246
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0133 0.0394
Loa Loa (eye worm) hypothetical protein 0.0079 0.0299 0.0307
Trichomonas vaginalis AGC family protein kinase 0.0135 0.0777 0.2803
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0104 0.0511 0.2036
Echinococcus multilocularis serine:threonine protein kinase N2 0.0201 0.1345 0.1578
Echinococcus multilocularis tyrosine protein kinase HCK 0.0145 0.0862 0.1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0216 0.1475 0.1566
Echinococcus granulosus serine:threonine protein kinase N2 0.0156 0.0958 0.0933
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.013 0.0732 0.0771
Echinococcus multilocularis serine:threonine protein kinase 38 0.0201 0.1345 0.1578
Onchocerca volvulus 0.0107 0.0537 0.1047
Loa Loa (eye worm) CAMK protein kinase 0.008 0.0305 0.0313
Toxoplasma gondii casein kinase I 0.013 0.0732 0.2714
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0122 0.0117
Loa Loa (eye worm) hypothetical protein 0.005 0.0049 0.0039
Brugia malayi hypothetical protein 0.01 0.048 0.0501
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0777 0.1499
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0079 0.0299 0.0307
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0474 0.1881
Loa Loa (eye worm) STAT protein 0.0051 0.0052 0.0043
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0118 0.0635 0.1224
Brugia malayi casein kinase 1, delta 0.013 0.0732 0.0771
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0154 0.0939 0.1811
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.026 0.1859 0.1978
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0084 0.0341 0.0376
Echinococcus multilocularis tyrosine protein kinase Abl 0.0213 0.1455 0.1709
Loa Loa (eye worm) hypothetical protein 0.0068 0.02 0.0201
Loa Loa (eye worm) hypothetical protein 0.0059 0.0127 0.0123
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0187 0.1224 0.4472
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Brugia malayi serine/threonine-protein kinase plk-2 0.0324 0.2404 0.2561
Schistosoma mansoni tyrosine kinase 0.0118 0.0635 0.1224
Onchocerca volvulus 0.009 0.0388 0.075
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0097 0.0451 0.047
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0061 0.0146 0.0142
Schistosoma mansoni tyrosine kinase 0.0166 0.105 0.2024
Giardia lamblia Kinase, CMGC DYRK 0.0166 0.1046 0.402
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0939 0.3408
Trypanosoma brucei cdc2-related kinase 3 0.0142 0.0837 0.3027
Echinococcus multilocularis casein kinase ii subunit alpha 0.0119 0.0644 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.1198 0.2309
Schistosoma mansoni tyrosine kinase 0.0289 0.2103 0.4054
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0184 0.1198 0.4923
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0224 0.1545 0.1817
Brugia malayi SH2 domain containing protein 0.0051 0.0052 0.0043
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0166 0.1046 0.1107
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0081 0.0318 0.0613
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Loa Loa (eye worm) transcription factor SMAD2 0.0625 0.4998 0.5338
Brugia malayi hypothetical protein 0.0068 0.02 0.0201
Schistosoma mansoni SH2A 0.0051 0.0052 0.0101
Schistosoma mansoni vesicular amine transporter 0.0081 0.0318 0.0613
Echinococcus multilocularis titin 0.008 0.0305 0.0333
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0837 0.3027
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0454 0.3526 0.3509
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0061 0.0144 0.0141
Schistosoma mansoni adapter molecule crk 0.0079 0.0299 0.0577
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0099 0.0468 0.0488
Brugia malayi Furin-like cysteine rich region family protein 0.0289 0.2103 0.2239
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0143 0.0276
Brugia malayi Protein kinase c protein 2 0.0138 0.0805 0.0849
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0135 0.0777 0.0753
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0135 0.0777 0.3156
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.006 0.0133 0.0394
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0159 0.0983 0.1144
Echinococcus granulosus unc 13 munc13 0.0052 0.0062 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0644 0.2304
Brugia malayi Stress-activated protein kinase jnk-1 0.0316 0.2342 0.2494
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0174 0.0335
Brugia malayi Tyrosine-protein kinase abl-1 0.0213 0.1455 0.1545
Brugia malayi protein unc-22 0.008 0.0305 0.0313
Echinococcus granulosus cyclin dependent kinase 1 0.0142 0.0837 0.0813
Brugia malayi Calcitonin receptor-like protein seb-1 0.0216 0.1475 0.1566
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Echinococcus granulosus expressed conserved protein 0.0051 0.0052 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0563 0.2001
Echinococcus granulosus fibroblast growth factor receptor 4 0.0277 0.2003 0.1981
Echinococcus granulosus Diacylglycerol kinase theta 0.005 0.0049 0.0023
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0106 0.0533 0.2127
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0204 0.0178
Trichomonas vaginalis STE family protein kinase 0.0163 0.1017 0.3697
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0474 0.1671
Echinococcus granulosus Protein kinase C brain isozyme 0.03 0.2201 0.218
Leishmania major cathepsin L-like protease 0.0069 0.021 0.0873
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.026 0.1853 0.1971
Leishmania major cathepsin L-like protease 0.0069 0.021 0.0873
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0043 0.0058
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0051 0.0052 0.0101
Echinococcus granulosus tyrosine protein kinase Src42A 0.0159 0.0983 0.0959
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0099 0.0468 0.1947
Echinococcus multilocularis SHC transforming protein 3 0.0051 0.0052 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Echinococcus granulosus dual specificity 0.0166 0.1046 0.1022
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0146 0.0873 0.3631
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0146 0.0873 0.0921
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0174 0.1113 0.1089
Brugia malayi MAP kinase sur-1 0.01 0.0474 0.0495
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0184 0.1198 0.4923
Schistosoma mansoni protein kinase 0.0231 0.1603 0.309
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Entamoeba histolytica protein kinase, putative 0.0358 0.2703 0.76
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0166 0.1046 0.3921
Brugia malayi Protein kinase domain containing protein 0.0201 0.1345 0.1428
Trichomonas vaginalis CAMK family protein kinase 0.0324 0.2404 0.8883
Echinococcus granulosus cyclin dependent kinase 0.0142 0.0837 0.0813
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0072 0.0239 0.0791
Entamoeba histolytica protein kinase, putative 0.0089 0.0385 0.1016
Echinococcus granulosus hypothetical protein 0.0145 0.0865 0.084
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.052 0.4096 0.4081
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0133 0.0394
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0119 0.0644 0.0676
Echinococcus granulosus contactin 0.0059 0.0122 0.0096
Trypanosoma brucei rac serine-threonine kinase, putative 0.0358 0.2703 1
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0051 0.0052 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0369 0.1277
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0097 0.0451 0.047
Entamoeba histolytica protein kinase, putative 0.0122 0.0665 0.1809
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0083 0.0232
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.006 0.0133 0.0394
Brugia malayi Fes/CIP4 homology domain containing protein 0.012 0.0648 0.0681
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0184 0.1198 0.4923
Entamoeba histolytica serine/threonine protein kinase, putative 0.0106 0.0533 0.1436
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0051 0.0052 0.0031
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0051 0.0052 0.0101
Brugia malayi Protein kinase domain containing protein 0.0276 0.1992 0.212
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.0388 0.0402
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0651 0.1256
Loa Loa (eye worm) hypothetical protein 0.0055 0.0091 0.0084
Echinococcus granulosus cGMP dependent protein kinase 0.0161 0.1001 0.0977
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0081 0.0318 0.0349
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0137 0.0799 0.0774
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0204 0.0206
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.052 0.4096 0.487
Brugia malayi Sex muscle abnormal protein 5 0.0079 0.0299 0.0307
Trypanosoma cruzi polo-like protein kinase, putative 0.0324 0.2404 1
Echinococcus multilocularis Glutaredoxin protein 5 0.0149 0.0896 0.104
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0101 0.0485 0.0548
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.0889 0.3219
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0149 0.0896 0.104
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0837 0.3027
Onchocerca volvulus Tyrosine kinase homolog 0.0436 0.3375 0.6713
Loa Loa (eye worm) hypothetical protein 0.0122 0.067 0.0705
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.01 0.0474 0.1974
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0533 0.1028
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.04 0.3061 0.3265
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0161 0.1001 0.1166
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0422 0.3255 0.3472
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0051 0.0052 0.008
Schistosoma mansoni tyrosine kinase 0.0295 0.216 0.4165
Schistosoma mansoni hypothetical protein 0.0148 0.0887 0.171
Giardia lamblia Kinase, CMGC CK2 0.0119 0.0644 0.225
Loa Loa (eye worm) phosphatidylinositol 3 0.0148 0.0889 0.0939
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0644 0.2304
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0135 0.0777 0.2803
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Onchocerca volvulus 0.0104 0.0511 0.0996
Brugia malayi Protein kinase domain 0.0102 0.0498 0.052
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.072 0.5814 0.6213
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0916 0.3319
Echinococcus multilocularis 0.0183 0.1192 0.1395
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0146 0.0873 0.3557
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0231 0.1603 0.1703
Schistosoma mansoni diacylglycerol kinase theta 0.005 0.0049 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.1306 0.2517
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0349 0.2624 0.2797
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0051 0.0052 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Trichomonas vaginalis STE family protein kinase 0.0102 0.0498 0.1759
Onchocerca volvulus 0.0375 0.2846 0.5657
Leishmania major casein kinase II, putative 0.0119 0.0644 0.2679
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0051 0.0052 0.0043
Echinococcus granulosus tyrosine protein kinase HCK 0.0145 0.0862 0.0837
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0302 0.2215 0.2359
Echinococcus granulosus casein kinase ii subunit alpha 0.0119 0.0644 0.0619
Brugia malayi RhoGAP domain containing protein 0.005 0.0049 0.0039
Schistosoma mansoni tyrosine kinase 0.0647 0.5187 1
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0451 0.087
Brugia malayi SH2 domain containing protein 0.0051 0.0052 0.0043
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0242 0.1704 0.1682
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0563 0.2001
Entamoeba histolytica cell division protein kinase 2, putative 0.0142 0.0837 0.23
Echinococcus multilocularis tyrosine protein kinase Srms 0.0195 0.1298 0.1521
Brugia malayi Protein kinase domain containing protein 0.0422 0.3255 0.3472
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0204 0.0213
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0474 0.1671
Echinococcus multilocularis calcium activated potassium channel 0.0161 0.1003 0.1169
Plasmodium falciparum NIMA related kinase 4 0.006 0.0133 0.0878
Schistosoma mansoni protein kinase 0.013 0.0732 0.1412
Loa Loa (eye worm) TK/INSR protein kinase 0.0252 0.179 0.1904
Brugia malayi p70 ribosomal S6 kinase beta 0.0349 0.2624 0.2797
Brugia malayi hypothetical protein 0.009 0.0388 0.0402
Echinococcus granulosus smoothened 0.0719 0.5806 0.5795
Echinococcus granulosus serine:threonine protein kinase N2 0.0356 0.2686 0.2667
Schistosoma mansoni protein kinase C mu 0.005 0.0049 0.0095
Echinococcus granulosus insulin receptor 0.0252 0.179 0.1768
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Echinococcus multilocularis unc 13 (munc13) 0.0052 0.0062 0.0042
Entamoeba histolytica hypothetical protein 0.0456 0.3547 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0106 0.0533 0.2127
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0161 0.1001 0.3747
Entamoeba histolytica hypothetical protein 0.0076 0.0274 0.0699
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.012 0.0651 0.2402
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0174 0.1113 0.3084
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.012 0.0651 0.0684
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0102 0.0498 0.0473
Loa Loa (eye worm) hypothetical protein 0.0367 0.2781 0.2965
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0104 0.0511 0.1808
Schistosoma mansoni nephrin 0.0059 0.0122 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0303 0.1031
Loa Loa (eye worm) hypothetical protein 0.0248 0.1754 0.1865
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0065 0.0174 0.0546
Onchocerca volvulus 0.0111 0.0573 0.112
Echinococcus multilocularis casein kinase I delta 0.013 0.0732 0.0844
Loa Loa (eye worm) TK/FAK protein kinase 0.0654 0.5249 0.5608
Echinococcus granulosus ephrin type A receptor 4 A 0.0116 0.0614 0.0589
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Brugia malayi serine/threonine protein kinase 6 0.0174 0.1113 0.1179
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0324 0.2404 0.2845
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0052 0.0062 0.0042
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0285 0.1083
Brugia malayi latrophilin 2 splice variant baaae 0.0148 0.0887 0.0936
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0537 0.1035
Echinococcus granulosus neuroglian 0.0104 0.0512 0.0486
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0224 0.1545 0.1817
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.1046 0.3806
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0154 0.0939 0.1092
Echinococcus multilocularis tyrosine protein kinase shark 0.0346 0.2596 0.3075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Schistosoma mansoni hypothetical protein 0.0076 0.0274 0.0528
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0135 0.0777 0.0819
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.1704 0.3285
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.2196 0.2339
Trichomonas vaginalis CAMK family protein kinase 0.026 0.1853 0.6822
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0285 0.1083
Giardia lamblia Kinase, CAMK CAMKL 0.0106 0.0533 0.1762
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0101 0.0485 0.0506
Giardia lamblia Kinase, NEK 0.0163 0.1017 0.3891
Echinococcus granulosus Immunoglobulin 0.0081 0.0318 0.0292
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0135 0.0777 0.0753
Entamoeba histolytica casein kinase 1, putative 0.013 0.0732 0.2002
Leishmania major serine/threonine-protein kinase, putative 0.006 0.0133 0.0553
Echinococcus multilocularis Immunoglobulin 0.0081 0.0318 0.0349
Entamoeba histolytica diacylglycerol kinase, putative 0.005 0.0049 0.0061
Brugia malayi Pleckstrin Homology Domain 0.0059 0.0127 0.0123
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0201 0.1345 0.1578
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0061 0.0145 0.0439
Loa Loa (eye worm) TK/ABL protein kinase 0.0339 0.2533 0.2699
Entamoeba histolytica protein kinase, putative 0.0174 0.1113 0.3084
Echinococcus multilocularis NCK adaptor protein 0.0082 0.032 0.0351
Giardia lamblia Kinase, CAMK CAMKL 0.0106 0.0533 0.1762
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0104 0.0511 0.2036
Echinococcus multilocularis death associated protein kinase 1 0.1018 0.8383 1
Schistosoma mansoni tyrosine kinase 0.0166 0.105 0.2024
Schistosoma mansoni protein kinase 0.0119 0.0644 0.1241
Brugia malayi hypothetical protein 0.0104 0.0511 0.0534
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0533 0.1028
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0563 0.2001
Echinococcus multilocularis epidermal growth factor receptor 0.0289 0.2103 0.2485
Trichomonas vaginalis CAMK family protein kinase 0.0324 0.2404 0.8883
Echinococcus granulosus casein kinase I alpha 0.013 0.0732 0.0708
Echinococcus multilocularis serine:threonine protein kinase N2 0.0356 0.2686 0.3183
Loa Loa (eye worm) hypothetical protein 0.005 0.0049 0.0039
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0195 0.1298 0.1521
Echinococcus granulosus dual specificity 0.0146 0.0873 0.0848
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0154 0.0939 0.0993
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0472 0.3686 0.3669
Echinococcus granulosus tyrosine protein kinase Lyn 0.0263 0.1877 0.1856
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0563 0.2001
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0154 0.0939 0.3511
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0563 0.2001
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.012 0.0651 0.0748
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0799 0.2883
Echinococcus granulosus roundabout 2 0.014 0.0823 0.0799
Onchocerca volvulus 0.009 0.0388 0.075
Schistosoma mansoni tyrosine kinase 0.0277 0.2003 0.3861
Entamoeba histolytica protein kinase domain containing protein 0.0154 0.0939 0.259
Echinococcus multilocularis casein kinase I alpha 0.013 0.0732 0.0844
Onchocerca volvulus 0.0154 0.0939 0.185
Loa Loa (eye worm) SH2 domain-containing protein 0.0051 0.0052 0.0043
Echinococcus granulosus mitogen activated protein kinase 14 0.019 0.1254 0.1231
Echinococcus multilocularis cyclin dependent kinase 5 0.0142 0.0837 0.097
Giardia lamblia Kinase, CMGC CDK 0.0142 0.0837 0.3101
Schistosoma mansoni serine/threonine-protein kinase 0.0196 0.1307 0.2519
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0154 0.0939 0.0993
Brugia malayi Tyrosine-protein kinase abl-1 0.0154 0.0941 0.0995
Leishmania major protein kinase, putative 0.0101 0.0484 0.2014
Schistosoma mansoni hypothetical protein 0.0122 0.067 0.1292
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0563 0.2001
Loa Loa (eye worm) phosphatidylinositol 3 0.005 0.0043 0.0033
Brugia malayi RhoGAP domain containing protein 0.0101 0.0485 0.0506
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0154 0.0939 0.3907
Echinococcus granulosus dual specificity 0.0166 0.1046 0.1022
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0163 0.1017 0.3808
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0187 0.1228 0.1205
Schistosoma mansoni ephrin receptor 0.0116 0.0614 0.1184
Loa Loa (eye worm) hypothetical protein 0.0064 0.0165 0.0164
Brugia malayi cell division control protein 2 homolog 0.0142 0.0837 0.0883
Toxoplasma gondii AGC kinase 0.0349 0.2624 1
Giardia lamblia Kinase, CMGC CLK 0.0184 0.1198 0.4688
Loa Loa (eye worm) hypothetical protein 0.005 0.0049 0.0039
Trypanosoma brucei cdc2-related kinase 1 0.0142 0.0837 0.3027
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0137 0.0799 0.0924
Entamoeba histolytica protein kinase, putative 0.0085 0.0352 0.0922
Echinococcus multilocularis tensin 0.0051 0.0052 0.0031
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0135 0.0777 0.0899
Echinococcus multilocularis cyclin dependent kinase 1 0.0142 0.0837 0.097
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.1843 0.3552
Schistosoma mansoni hypothetical protein 0.0051 0.0052 0.0101
Echinococcus granulosus protein tyrosine kinase 0.0647 0.5187 0.5174
Loa Loa (eye worm) hypothetical protein 0.0145 0.0865 0.0913
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0271 0.1952 0.193
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0242 0.1704 0.2008
Loa Loa (eye worm) hypothetical protein 0.0104 0.0511 0.0534
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0184 0.1198 0.4373
Onchocerca volvulus 0.013 0.0732 0.1437
Echinococcus granulosus N chimaerin 0.0101 0.0485 0.046
Schistosoma mansoni vav2 0.011 0.0563 0.1086
Onchocerca volvulus 0.0051 0.0052 0.008
Entamoeba histolytica protein kinase, putative 0.0099 0.0468 0.1251
Trypanosoma brucei protein kinase, putative 0.0154 0.0939 0.3408
Entamoeba histolytica protein kinase, putative 0.0146 0.0873 0.2401
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.012 0.0651 0.5195
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0099 0.0468 0.1853
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0148 0.0889 0.3624
Echinococcus multilocularis nervana 2 0.0149 0.0896 0.104
Echinococcus multilocularis dual specificity 0.0166 0.1046 0.122
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0303 0.1031
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.01 0.0474 0.1881
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Schistosoma mansoni tyrosine kinase 0.0288 0.2097 0.4043
Brugia malayi putative serine/threonine kinase SADA gamma 0.0106 0.0533 0.0558
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0101 0.0485 0.0935
Schistosoma mansoni tensin 0.0051 0.0052 0.0101
Brugia malayi Protein kinase domain containing protein 0.0146 0.0873 0.0921
Echinococcus multilocularis serine:threonine protein kinase 0.0136 0.0789 0.0912
Echinococcus granulosus roundabout 2 0.0059 0.0122 0.0096
Giardia lamblia Kinase, CMGC SRPK 0.0099 0.0468 0.1475
Brugia malayi casein kinase I 0.013 0.0732 0.0771
Onchocerca volvulus 0.0051 0.0052 0.008
Trichomonas vaginalis STE family protein kinase 0.0102 0.0498 0.1759
Giardia lamblia Kinase, STE STE20 0.0101 0.0484 0.1546
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.0388 0.0402
Loa Loa (eye worm) CDC7 protein kinase 0.0107 0.0537 0.0562
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.012 0.0651 0.0684
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0122 0.0117
Trichomonas vaginalis CK1 family protein kinase 0.013 0.0732 0.2634
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1001 0.1929
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0184 0.1198 0.1269
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.007 0.0218 0.0712
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.0388 0.0402
Brugia malayi Variant SH3 domain containing protein 0.0079 0.0299 0.0307
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Loa Loa (eye worm) SRC-1 0.0224 0.1545 0.1641
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0224 0.1545 0.1817
Schistosoma mansoni serine/threonine-protein kinase 0.0196 0.1307 0.2519
Giardia lamblia Kinase, CMGC GSK 0.0154 0.0939 0.355
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0173 0.1106 0.1292
Brugia malayi Doublecortin family protein 0.018 0.1168 0.1238
Brugia malayi Protein kinase domain containing protein 0.009 0.0388 0.0402
Entamoeba histolytica protein kinase domain containing protein 0.0166 0.1046 0.2893
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0258 0.1843 0.1821
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0224 0.1545 0.1817
Echinococcus granulosus epidermal growth factor receptor 0.0289 0.2103 0.2082
Schistosoma mansoni hypothetical protein 0.0051 0.0052 0.0101
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0278 0.2014 0.2379
Leishmania major protein kinase, putative 0.0048 0.0028 0.0115
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0102 0.0498 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0385 0.0742
Entamoeba histolytica protein kinase, putative 0.0146 0.0873 0.2401
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0644 0.2304
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0274 0.0248
Echinococcus multilocularis 0.0051 0.0052 0.0031
Echinococcus multilocularis serine:threonine protein kinase 3 0.0308 0.2265 0.2678
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.2342 0.4515
Echinococcus granulosus calcium activated potassium channel 0.0161 0.1003 0.0979
Trichomonas vaginalis CAMK family protein kinase 0.012 0.0651 0.2332
Schistosoma mansoni tensin-related 0.0051 0.0052 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0133 0.0256
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0523 0.1009
Echinococcus multilocularis roundabout 2 0.0059 0.0122 0.0114
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0161 0.1001 0.1166
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Echinococcus granulosus serine threonine protein kinase nrc 0.0187 0.1228 0.1205
Echinococcus multilocularis CDC7 cell division cycle 7 0.0107 0.0537 0.0611
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0065 0.0174 0.0173
Plasmodium falciparum NIMA related kinase 1 0.0163 0.1017 0.8236
Brugia malayi Hr1 repeat family protein 0.0356 0.2686 0.2864
Trichomonas vaginalis AGC family protein kinase 0.0225 0.1557 0.5717
Trichomonas vaginalis CAMK family protein kinase 0.0324 0.2404 0.8883
Brugia malayi Immunoglobulin I-set domain containing protein 0.0513 0.4033 0.4306
Giardia lamblia Kinase, CMGC CDK 0.0142 0.0837 0.3101
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0324 0.2404 1
Trichomonas vaginalis AGC family protein kinase 0.0097 0.0451 0.1583
Loa Loa (eye worm) hypothetical protein 0.0167 0.1052 0.1113
Echinococcus granulosus suppressor of cytokine signaling 6 0.0051 0.0052 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.1198 0.2309
Echinococcus multilocularis mitogen activated protein kinase 14 0.019 0.1254 0.1469
Echinococcus granulosus SH2 motif 0.0051 0.0052 0.0026
Schistosoma mansoni protein kinase 0.0102 0.0498 0.096
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Brugia malayi SH2 domain containing protein 0.0051 0.0052 0.0043
Toxoplasma gondii NEK kinase 0.006 0.0133 0.0406
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0099 0.0468 0.0442
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.01 0.0474 0.1721
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0251 0.1778 0.2096
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0065 0.0174 0.0173
Brugia malayi Protein kinase domain containing protein 0.113 0.9351 1
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.019 0.1254 0.133
Giardia lamblia Kinase, AGC AKT 0.014 0.0819 0.3022
Trypanosoma cruzi casein kinase, putative 0.013 0.0732 0.2966
Schistosoma mansoni signal transduction protein lnk-related 0.0051 0.0052 0.0101
Trypanosoma brucei protein kinase, putative 0.01 0.0474 0.1671
Mycobacterium ulcerans hypothetical protein 0.0122 0.0668 0.5
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0101 0.0484 0.1706
Trichomonas vaginalis AGC family protein kinase 0.0174 0.1113 0.4058
Brugia malayi Protein kinase domain containing protein 0.0225 0.1557 0.1654
Brugia malayi SH2 domain containing protein 0.0051 0.0052 0.0043
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0051 0.0052 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.2215 0.4271
Trypanosoma cruzi casein kinase II, putative 0.0119 0.0644 0.2594
Echinococcus granulosus tyrosine protein kinase Fyn 0.0224 0.1545 0.1522
Schistosoma mansoni serine/threonine protein kinase 0.03 0.2201 0.4244
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0204 0.0178
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0051 0.0052 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Trypanosoma cruzi casein kinase, putative 0.013 0.0732 0.2966
Echinococcus granulosus serine:threonine protein kinase 0.0136 0.0789 0.0764
Loa Loa (eye worm) hypothetical protein 0.0121 0.0662 0.0695
Echinococcus multilocularis nervana 2 0.0149 0.0896 0.104
Echinococcus granulosus tyrosine protein kinase Srms 0.0579 0.4605 0.459
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0059 0.0122 0.0117
Echinococcus granulosus protein kinase c eta type 0.005 0.0049 0.0023
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0106 0.0533 0.421
Brugia malayi Protein kinase domain containing protein 0.0097 0.0451 0.047
Loa Loa (eye worm) hypothetical protein 0.0098 0.0459 0.0479
Echinococcus multilocularis serine threonine protein kinase 0.025 0.1769 0.2085
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0474 0.1671
Trypanosoma brucei SNF1-related protein kinases, putative 0.0106 0.0533 0.189
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0133 0.0394
Giardia lamblia Aurora kinase 0.0174 0.1113 0.4316
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0142 0.0837 0.3118
Schistosoma mansoni cellular tumor antigen P53 0.0111 0.0573 0.1105
Leishmania major protein kinase, putative 0.0184 0.1198 0.4982
Echinococcus multilocularis 0.0145 0.0865 0.1003
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0224 0.1545 0.1817
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0222 0.153 0.1799
Echinococcus granulosus tyrosine kinase 0.009 0.0388 0.0362
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0187 0.1228 0.1438
Echinococcus granulosus SH2 domain containing adapter protein F 0.0051 0.0052 0.0026
Entamoeba histolytica protein kinase, putative 0.0201 0.1345 0.3744
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.04 0.3061 0.3265
Loa Loa (eye worm) hypothetical protein 0.0103 0.0504 0.0527
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0224 0.1545 0.1817
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.012 0.0651 0.5195
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0302 0.1027
Echinococcus granulosus netrin receptor unc 5 0.0052 0.0065 0.0039
Loa Loa (eye worm) hypothetical protein 0.0415 0.319 0.3403
Brugia malayi Protein kinase domain containing protein 0.0073 0.0248 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0703 0.2524
Brugia malayi map kinase activated protein kinase protein 2 0.0472 0.3686 0.3933
Entamoeba histolytica protein kinase, putative 0.0349 0.2624 0.7378
Onchocerca volvulus 0.039 0.2971 0.5906
Echinococcus granulosus protein kinase c iota type 0.0351 0.2635 0.2616
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0278 0.2009 0.2138
Echinococcus multilocularis Diacylglycerol kinase theta 0.005 0.0049 0.0027
Entamoeba histolytica SH2-protein kinase domain containing protein 0.009 0.0388 0.1024
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0248 0.1754 0.1732
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0224 0.1545 0.1817
Onchocerca volvulus 0.009 0.0388 0.075
Leishmania major protein kinase, putative 0.012 0.0651 0.271
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.1778 0.3428
Onchocerca volvulus 0.0167 0.1052 0.2075
Trichomonas vaginalis CAMK family protein kinase 0.0324 0.2404 0.8883
Plasmodium falciparum calcium-dependent protein kinase 3 0.012 0.0651 0.5195
Echinococcus granulosus c-Jun N-terminal kinases 0.0316 0.2342 0.2321
Brugia malayi intracellular kinase 0.0154 0.0939 0.0993
Loa Loa (eye worm) hypothetical protein 0.0704 0.5678 0.6067
Brugia malayi hypothetical protein 0.0531 0.4191 0.4474
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0339 0.2533 0.3
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0106 0.0533 0.0606
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0089 0.0385 0.1016
Trichomonas vaginalis STE family protein kinase 0.0101 0.0484 0.1706
Brugia malayi tRNA modification GTPase TrmE family protein 0.0051 0.0052 0.0043
Brugia malayi P38 map kinase family protein 2 0.019 0.1254 0.133
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Echinococcus granulosus casein kinase I alpha 0.013 0.0732 0.0708
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0187 0.1228 1
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.024 0.1684 0.1984
Schistosoma mansoni ste20-related kinase 0.0245 0.173 0.3335
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Trypanosoma cruzi casein kinase, putative 0.013 0.0732 0.2966
Brugia malayi Protein kinase domain containing protein 0.072 0.5814 0.6213
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0173 0.1106 0.1083
Echinococcus multilocularis serine:threonine protein kinase 0.0136 0.0789 0.0912
Brugia malayi serine/threonine-protein kinase PAK 7 0.0278 0.2009 0.2138
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.0388 0.0402
Trypanosoma cruzi p21-activated kinase 3, putative 0.0065 0.0174 0.0615
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0072 0.0239 0.0791
Plasmodium falciparum calcium-dependent protein kinase 2 0.012 0.0651 0.5195
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0149 0.0898 0.3734
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0414 0.3181 0.3393
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0135 0.0777 0.6245
Echinococcus multilocularis epidermal growth factor receptor 0.0205 0.1385 0.1626
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0184 0.1198 0.4923
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0051 0.0052 0.008
Schistosoma mansoni atypical protein kinase C 0.0358 0.2698 0.5202
Loa Loa (eye worm) hypothetical protein 0.0135 0.0777 0.0819
Schistosoma mansoni serine/threonine protein kinase 0.0572 0.4542 0.8756
Plasmodium falciparum protein kinase 5 0.0142 0.0837 0.6742
Onchocerca volvulus 0.0172 0.1094 0.2159
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0135 0.0777 0.6245
Trypanosoma cruzi cdc2-related kinase 1 0.0142 0.0837 0.3407
Echinococcus multilocularis dual specificity 0.0166 0.1046 0.122
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0277 0.2003 0.2365
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0099 0.0468 0.1696
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0043 0.0058
Entamoeba histolytica protein kinase, putative 0.0145 0.0862 0.237
Plasmodium vivax serine/threonine protein kinase, putative 0.0099 0.0468 0.3667
Echinococcus granulosus cGMP dependent protein kinase 1 0.0161 0.1001 0.0977
Echinococcus granulosus tyrosine protein kinase Fyn 0.0224 0.1545 0.1522
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.01 0.0474 0.1671
Schistosoma mansoni tyrosine kinase 0.0079 0.0296 0.057
Brugia malayi SH2 domain containing protein 0.0051 0.0052 0.0043
Echinococcus granulosus protein kinase 0.0183 0.1192 0.1169
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0148 0.0889 0.0939
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.1345 0.2594
Schistosoma mansoni serine/threonine protein kinase 0.024 0.1685 0.3248
Echinococcus multilocularis neuroglian 0.0104 0.0512 0.058
Loa Loa (eye worm) hypothetical protein 0.0082 0.0321 0.0331
Brugia malayi hypothetical protein 0.0266 0.1907 0.2029
Loa Loa (eye worm) camk/dcamkl protein kinase 0.018 0.1168 0.1238
Entamoeba histolytica PH domain containing protein kinase, putative 0.0144 0.0856 0.2353
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.006 0.0133 0.0444
Loa Loa (eye worm) TK/EGFR protein kinase 0.0289 0.2103 0.2239
Onchocerca volvulus Netrin receptor homolog 0.0057 0.0109 0.0193
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Echinococcus granulosus protein kinase shaggy 0.0154 0.0939 0.0915
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0096 0.0446 0.3487
Trypanosoma cruzi polo-like protein kinase, putative 0.0324 0.2404 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0043 0.0058
Echinococcus granulosus epidermal growth factor receptor 0.0205 0.1385 0.1362
Brugia malayi Tensin 0.0051 0.0052 0.0043
Loa Loa (eye worm) hypothetical protein 0.0068 0.0204 0.0206
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.024 0.1684 0.1662
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0059 0.0122 0.0114
Echinococcus multilocularis N chimaerin 0.0101 0.0485 0.0548
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0154 0.0939 0.3837
Echinococcus multilocularis survival motor neuron protein 1 0.0531 0.4191 0.4983
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0644 0.2304
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0148 0.0889 0.2447
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0442 0.1551
Echinococcus granulosus suppressor of cytokine signaling 7 0.0051 0.0052 0.0026
Loa Loa (eye worm) MH2 domain-containing protein 0.0625 0.4998 0.5338
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0163 0.1017 0.8236
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0108 0.0549 0.0575
Brugia malayi Protein kinase domain containing protein 0.0654 0.5249 0.5608
Trichomonas vaginalis CAMK family protein kinase 0.0324 0.2404 0.8883
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0252 0.1791 0.1905
Schistosoma mansoni hypothetical protein 0.0068 0.0204 0.0394
Loa Loa (eye worm) raf kinase 0.005 0.0049 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.021 0.0767
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0196 0.1306 0.1531
Schistosoma mansoni unc-13 (munc13) 0.0052 0.0062 0.012
Entamoeba histolytica protein kinase, putative 0.0084 0.0341 0.0891
Echinococcus granulosus tyrosine protein kinase Src64B 0.0224 0.1545 0.1522
Echinococcus granulosus serine:threonine protein kinase 3 0.0308 0.2265 0.2244
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0196 0.1306 0.1385
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0104 0.0511 0.0986
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0916 0.3319
Echinococcus multilocularis tensin 0.0051 0.0052 0.0031
Echinococcus granulosus signal transduction protein lnk realted 0.0051 0.0052 0.0026
Schistosoma mansoni suppressor of cytokine signaling 0.0051 0.0052 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1001 0.1929
Brugia malayi probable protein kinase 0.0287 0.2087 0.2222
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0537 0.1904
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0146 0.0873 0.3557
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0222 0.153 0.1625
Loa Loa (eye worm) hypothetical protein 0.005 0.0049 0.0039
Schistosoma mansoni protein kinase 0.052 0.4096 0.7897
Trypanosoma cruzi cdc2-related kinase 1 0.0142 0.0837 0.3407
Echinococcus multilocularis serine:threonine protein kinase N2 0.0156 0.0958 0.1114
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.1046 0.3806
Brugia malayi Protein kinase domain containing protein 0.0107 0.0537 0.0562
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0224 0.1545 0.1522
Echinococcus granulosus mitogen activated protein kinase 0.01 0.0474 0.0449
Echinococcus multilocularis aurora kinase A 0.0174 0.1113 0.13
Echinococcus multilocularis calcium dependent protein kinase 0.0082 0.0319 0.0349
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0051 0.0052 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0234 0.1635 0.6009
Echinococcus granulosus defective proboscis extension response 0.0081 0.0318 0.0292
Echinococcus multilocularis expressed conserved protein 0.0161 0.1001 0.1166
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.012 0.0651 0.0627
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0593 0.4722 0.5619
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Schistosoma mansoni hypothetical protein 0.0104 0.0511 0.0986
Echinococcus granulosus CDC7 cell division cycle 7 0.0107 0.0537 0.0512
Plasmodium vivax protein kinase, putative 0.0057 0.0108 0.067
Schistosoma mansoni protein kinase 0.0287 0.2087 0.4024
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.047 0.1653
Onchocerca volvulus 0.009 0.0388 0.075
Brugia malayi SRC-1 0.0224 0.1545 0.1641
Onchocerca volvulus 0.0051 0.0052 0.008
Plasmodium vivax glycogen synthase kinase 3, putative 0.0154 0.0939 0.7592
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0135 0.0777 0.2888
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Loa Loa (eye worm) AGC/PKG protein kinase 0.0161 0.1001 0.1058
Trichomonas vaginalis AGC family protein kinase 0.0097 0.0451 0.1583
Leishmania major protein kinase A catalytic subunit isoform 1 0.0135 0.0777 0.3234
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0644 0.2304
Loa Loa (eye worm) hypothetical protein 0.0106 0.0533 0.0558
Loa Loa (eye worm) AGC/PKA protein kinase 0.0135 0.0777 0.0819
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0011 0.0022
Loa Loa (eye worm) TK/FER protein kinase 0.0454 0.3526 0.3762
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.005 0.0043 0.0066
Echinococcus multilocularis neuroglian 0.0059 0.0122 0.0114
Loa Loa (eye worm) hypothetical protein 0.0107 0.054 0.0565
Brugia malayi Egg laying defective protein 4 0.0161 0.1001 0.1058
Giardia lamblia Kinase, AGC PKA 0.0135 0.0777 0.2838
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0174 0.1113 0.13
Loa Loa (eye worm) hypothetical protein 0.005 0.0049 0.0039
Loa Loa (eye worm) hypothetical protein 0.0077 0.0279 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0356 0.2686 0.5179
Brugia malayi Protein kinase domain containing protein 0.0538 0.4248 0.4535
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0106 0.0533 0.189
Trichomonas vaginalis STE family protein kinase 0.0102 0.0498 0.1759
Toxoplasma gondii CMGC kinase, CK2 family 0.0119 0.0644 0.2373
Echinococcus granulosus rho-associated protein kinase 1 0.039 0.2971 0.2953
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.0388 0.0402
Schistosoma mansoni tyrosine kinase 0.0224 0.1545 0.2978
Trichomonas vaginalis PIKK family atypical protein kinase 0.0148 0.0889 0.3219
Loa Loa (eye worm) AUR protein kinase 0.0174 0.1113 0.1179
Schistosoma mansoni tyrosine kinase 0.0346 0.2596 0.5005
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0148 0.0889 0.2447
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0096 0.0445 0.05
Echinococcus granulosus mitogen activated protein kinase 11 0.019 0.1254 0.1231
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0258 0.1843 0.1821
Echinococcus multilocularis rho associated protein kinase 0.039 0.2971 0.3524
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0166 0.1046 0.4351
Loa Loa (eye worm) hypothetical protein 0.0167 0.1052 0.1113
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0258 0.1843 0.2173
Brugia malayi serine/threonine-protein kinase 6 0.0174 0.1113 0.1179
Brugia malayi Protein kinase domain containing protein 0.0327 0.2432 0.2591
Loa Loa (eye worm) TK protein kinase 0.0195 0.1298 0.1376
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0513 0.4033 0.4306
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0308 0.2265 0.2412
Echinococcus granulosus Glutaredoxin protein 5 0.0149 0.0896 0.0871
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0106 0.0533 0.0558
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0081 0.0318 0.0613
Loa Loa (eye worm) hypothetical protein 0.0148 0.0887 0.0936
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.005 0.0043 0.0083
Onchocerca volvulus 0.008 0.0305 0.0584
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.1843 0.3552
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0065 0.0057
Echinococcus multilocularis expressed protein 0.0099 0.0468 0.0528
Brugia malayi RhoGEF domain containing protein 0.005 0.0049 0.0039
Brugia malayi Protein kinase domain containing protein 0.009 0.0388 0.0402
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.0388 0.0402
Loa Loa (eye worm) hypothetical protein 0.006 0.0131 0.0127
Schistosoma mansoni tyrosine kinase 0.0118 0.0635 0.1224
Loa Loa (eye worm) hypothetical protein 0.0107 0.054 0.0565
Entamoeba histolytica serine/threonine protein kinase, putative 0.0324 0.2404 0.6751
Echinococcus granulosus titin 0.008 0.0305 0.0279
Brugia malayi hypothetical protein 0.0051 0.0052 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Echinococcus multilocularis smoothened 0.0719 0.5806 0.6916
Echinococcus multilocularis c src tyrosine kinase 0.0118 0.0635 0.0728
Entamoeba histolytica protein kinase, putative 0.0358 0.2703 0.76
Onchocerca volvulus 0.009 0.0388 0.075
Onchocerca volvulus 0.0077 0.0279 0.0532
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.1113 0.2146
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0079 0.0299 0.0577
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.1907 0.3676
Echinococcus multilocularis signal transduction protein lnk realted 0.0051 0.0052 0.0031
Trichomonas vaginalis AGC family protein kinase 0.0174 0.1113 0.4058
Loa Loa (eye worm) AGC/NDR protein kinase 0.0201 0.1345 0.1428
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0174 0.1113 0.3084
Echinococcus multilocularis casein kinase I alpha 0.013 0.0732 0.0844
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Loa Loa (eye worm) hypothetical protein 0.0104 0.0511 0.0534
Loa Loa (eye worm) AUR protein kinase 0.0174 0.1113 0.1179
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0183 0.1192 0.1264
Entamoeba histolytica protein kinase, putative 0.012 0.0651 0.1772
Trichomonas vaginalis AGC family protein kinase 0.0358 0.2703 1
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0104 0.0511 0.058
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0051 0.0052 0.0031
Plasmodium vivax unspecified product 0.0119 0.0644 0.5132
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0143 0.0844 0.082
Loa Loa (eye worm) hypothetical protein 0.0172 0.1094 0.1158
Brugia malayi Protein kinase domain containing protein 0.0252 0.179 0.1904
Echinococcus multilocularis mitogen activated protein kinase 3 0.01 0.0474 0.0536
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0468 0.0902
Onchocerca volvulus 0.0107 0.0537 0.1047
Schistosoma mansoni rac gtpase activating protein 0.005 0.0049 0.0095
Echinococcus multilocularis roundabout 2 0.014 0.0823 0.0954
Toxoplasma gondii aurora kinase 0.0174 0.1113 0.418
Giardia lamblia Kinase, CK1 Casein kinase 0.013 0.0732 0.2639
Loa Loa (eye worm) thyroid receptor interactor 0.012 0.0648 0.0681
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Schistosoma mansoni netrin receptor unc5 0.0052 0.0065 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0533 0.1028
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0101 0.0485 0.0935
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0358 0.2703 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0142 0.0837 0.097
Brugia malayi Protein kinase domain containing protein 0.0358 0.2703 0.2881
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0102 0.0498 0.0473
Toxoplasma gondii diacylglycerol kinase, putative 0.005 0.0049 0.0083
Entamoeba histolytica protein kinase domain containing protein 0.0174 0.1113 0.3084
Loa Loa (eye worm) hypothetical protein 0.0104 0.0511 0.0534
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Echinococcus granulosus serine:threonine kinase SAD 1 0.0106 0.0533 0.0508
Brugia malayi Variant SH3 domain containing protein 0.0101 0.0485 0.0506
Loa Loa (eye worm) hypothetical protein 0.0048 0.0027 0.0015
Trichomonas vaginalis CK1 family protein kinase 0.013 0.0732 0.2634
Echinococcus granulosus NCK adaptor protein 0.0079 0.0299 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0043 0.0058
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0266 0.1907 0.2029
Schistosoma mansoni serine/threonine protein kinase 0.03 0.2201 0.4244
Onchocerca volvulus 0.0051 0.0052 0.008
Loa Loa (eye worm) hypothetical protein 0.0167 0.1052 0.1113
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0051 0.0052 0.0026
Echinococcus multilocularis PAK box P21 Rho binding 0.0076 0.0274 0.0296
Schistosoma mansoni protein kinase 0.0174 0.1113 0.2146
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0154 0.0939 0.0915
Leishmania major phosphatidylinositol 3-related kinase, putative 0.005 0.0043 0.018
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0285 0.0962
Echinococcus granulosus nervana 2 0.0149 0.0896 0.0871
Brugia malayi cytokine inducible SH2-containing protein 5 0.0051 0.0052 0.0043
Echinococcus granulosus expressed protein 0.0099 0.0468 0.0443
Schistosoma mansoni protein kinase C 0.0052 0.0062 0.012
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0305 0.0588
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0135 0.0777 0.2803
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0166 0.1046 0.3806
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0474 0.1881
Entamoeba histolytica SH2 domain containing protein 0.0051 0.0052 0.007
Echinococcus granulosus serine/threonine protein kinase 0.0196 0.1307 0.1283
Echinococcus multilocularis casein kinase I gamma 0.0255 0.1814 0.2139
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Trichomonas vaginalis AGC family protein kinase 0.0358 0.2703 1
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0422 0.3255 0.3472
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Schistosoma mansoni kinase 0.0346 0.2595 0.5002
Brugia malayi Protein kinase domain containing protein 0.024 0.1685 0.1791
Echinococcus granulosus tensin 0.0051 0.0052 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0533 0.189
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.0388 0.0402
Entamoeba histolytica p21-activated kinase 0.0111 0.0576 0.1559
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.021 0.0767
Plasmodium vivax serine/threonine kinase-1, putative 0.0184 0.1198 0.9743
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.1778 0.3428
Echinococcus granulosus cGMP dependent protein kinase 1 0.0161 0.1001 0.0977
Echinococcus granulosus growth factor receptor bound protein 2 0.0082 0.032 0.0294
Echinococcus granulosus activin receptor type 0.0078 0.0285 0.0259
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0266 0.1907 0.225
Giardia lamblia Kinase, STE STE20 0.0102 0.0498 0.1608
Brugia malayi Protein kinase domain containing protein 0.009 0.0388 0.0402
Loa Loa (eye worm) hypothetical protein 0.0554 0.4389 0.4687
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0196 0.1307 0.5383
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0097 0.0455 0.0474
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0148 0.0889 0.1032
Trypanosoma brucei protein kinase, putative 0.0078 0.0285 0.0962
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0084 0.0341 0.0315
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.005 0.0049 0.0039
Echinococcus granulosus casein kinase I delta 0.013 0.0732 0.0708
Echinococcus granulosus neuroglian 0.0059 0.0122 0.0096
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0225 0.1557 0.1654
Leishmania major folate/biopterin transporter, putative 0.0048 0.0028 0.0115
Brugia malayi Protein kinase domain containing protein 0.0136 0.0789 0.0831
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0454 0.3526 0.4188
Schistosoma mansoni protein kinase 0.0078 0.0285 0.0549
Brugia malayi Protein kinase domain containing protein 0.0255 0.1814 0.1929
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.0388 0.0402
Loa Loa (eye worm) AGC/PKN protein kinase 0.0356 0.2686 0.2864
Schistosoma mansoni tyrosine kinase 0.0252 0.179 0.3451
Onchocerca volvulus 0.0222 0.1526 0.3022
Plasmodium falciparum protein kinase, putative 0.0078 0.0285 0.2143
Onchocerca volvulus 0.007 0.0217 0.0409
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0341 0.0658
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0302 0.1027
Trypanosoma brucei Casein kinase II 0.0119 0.0644 0.2304
Brugia malayi Protein kinase domain containing protein 0.009 0.0388 0.0402
Schistosoma mansoni shc transforming protein 0.0051 0.0052 0.0101
Entamoeba histolytica protein kinase, putative 0.0085 0.0352 0.0922
Echinococcus multilocularis mitogen activated protein kinase 14 0.019 0.1254 0.1469
Giardia lamblia Kinase, CMGC GSK 0.0154 0.0939 0.355
Brugia malayi Protein kinase domain containing protein 0.009 0.0388 0.0402
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0204 0.0206
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0258 0.1843 0.2173
Plasmodium falciparum serine/threonine protein kinase, putative 0.0174 0.1113 0.904
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0063 0.0161 0.0498
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.012 0.0651 0.0748
Loa Loa (eye worm) hypothetical protein 0.0068 0.02 0.0201
Schistosoma mansoni protein kinase 0.0264 0.1893 0.365
Schistosoma mansoni tyrosine kinase 0.0205 0.1385 0.2671
Brugia malayi Immunoglobulin I-set domain containing protein 0.008 0.0305 0.0313
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0302 0.1027
Onchocerca volvulus 0.0091 0.0399 0.0773
Trichomonas vaginalis AGC family protein kinase 0.0063 0.0161 0.0498
Giardia lamblia Kinase, CMGC MAPK 0.01 0.0474 0.1504
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0096 0.0446 0.1613
Toxoplasma gondii target of rapamycin (TOR), putative 0.011 0.0563 0.2061
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0135 0.0777 0.0753
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0271 0.1952 0.2304
Loa Loa (eye worm) hypothetical protein 0.0136 0.0789 0.0831
Echinococcus multilocularis tyrosine kinase 0.009 0.0388 0.0432
Trichomonas vaginalis AGC family protein kinase 0.0072 0.0239 0.0791
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0242 0.1704 0.1812
Trichomonas vaginalis AGC family protein kinase 0.0225 0.1557 0.5717
Loa Loa (eye worm) hypothetical protein 0.0051 0.0052 0.0043
Onchocerca volvulus 0.0628 0.5022 1
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0148 0.0889 0.0864
Brugia malayi diacylglycerol kinase 0.005 0.0049 0.0039
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0142 0.0837 0.3483
Echinococcus granulosus SHC transforming protein 3 0.0051 0.0052 0.0026
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0422 0.3255 0.3237
Entamoeba histolytica hypothetical protein 0.0146 0.0873 0.2401
Brugia malayi STE20-like kinase MST 0.0308 0.2265 0.2412
Loa Loa (eye worm) casein kinase 0.0216 0.1481 0.1573
Echinococcus granulosus roundabout 2 0.0059 0.0122 0.0096
Echinococcus multilocularis Immunoglobulin 0.0081 0.0318 0.0349
Brugia malayi hypothetical protein 0.0076 0.0274 0.028
Trichomonas vaginalis AGC family protein kinase 0.0358 0.2703 1
Echinococcus granulosus myotubularin protein 13 0.0059 0.0127 0.0101
Onchocerca volvulus 0.0108 0.0549 0.1072
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0084 0.0341 0.0315
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.005 0.0043 0.0066
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0277 0.2003 0.1981
Leishmania major casein kinase, putative 0.013 0.0732 0.3046
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0142 0.0837 0.3483
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0201 0.1345 0.1578
Plasmodium vivax casein kinase 1, putative 0.013 0.0732 0.5868
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.006 0.0133 0.0878
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.005 0.0043 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0097 0.0451 0.1583
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.1791 0.3453
Schistosoma mansoni tyrosine kinase 0.0166 0.105 0.2024
Brugia malayi C1-like domain containing protein 0.026 0.1859 0.1978
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0088 0.0373 0.0386
Entamoeba histolytica protein kinase, putative 0.0099 0.0468 0.1251
Echinococcus granulosus calcium dependent protein kinase 0.0082 0.0319 0.0293
Echinococcus granulosus tyrosine protein kinase ABL1 0.0339 0.2533 0.2513
Giardia lamblia Kinase, NEK 0.0163 0.1017 0.3891
Giardia lamblia Kinase, NEK 0.0163 0.1017 0.3891
Schistosoma mansoni titin 0.008 0.0305 0.0588
Trypanosoma cruzi cdc2-related kinase 3 0.0142 0.0837 0.3407
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0837 0.1614
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0187 0.1228 0.5053
Entamoeba histolytica protein kinase domain containing protein 0.0078 0.0285 0.0731
Trypanosoma cruzi casein kinase, putative 0.013 0.0732 0.2966
Trichomonas vaginalis AGC family protein kinase 0.0358 0.2703 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.021 0.0681
Giardia lamblia GTOR 0.0148 0.0889 0.3328
Echinococcus granulosus c src tyrosine kinase 0.0118 0.0635 0.061
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0052 0.0062 0.0036
Schistosoma mansoni hypothetical protein 0.0122 0.067 0.1292
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0316 0.2342 0.277
Schistosoma mansoni hypothetical protein 0.005 0.0049 0.0095
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0148 0.0889 0.3219
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.006 0.0133 0.0553
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0135 0.0777 0.2803
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.005 0.0043 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0117 0.0628 0.2246
Brugia malayi Variant SH3 domain containing protein 0.0061 0.0144 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.039 0.2971 0.5728
Schistosoma mansoni hypothetical protein 0.0068 0.0204 0.0394
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0135 0.0777 0.0899
Echinococcus granulosus tyrosine protein kinase Blk 0.0195 0.1298 0.1274
Trichomonas vaginalis AGC family protein kinase 0.0201 0.1345 0.4926
Schistosoma mansoni unc-13 (munc13) 0.0053 0.0077 0.0149
Brugia malayi Protein kinase domain containing protein 0.0232 0.1612 0.1713
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0148 0.0889 0.3697
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0422 0.3255 0.6473
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.01 0.0474 0.1974
Echinococcus multilocularis SH2 domain containing protein 7 0.0051 0.0052 0.0031
Echinococcus multilocularis SH2 motif 0.0051 0.0052 0.0031
Schistosoma mansoni tensin-related 0.0051 0.0052 0.0101
Echinococcus multilocularis SH2 motif 0.0051 0.0052 0.0031
Schistosoma mansoni tyrosine kinase 0.0252 0.179 0.3451
Plasmodium falciparum serine/threonine protein kinase 0.0099 0.0468 0.3667
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0102 0.0498 0.0564
Toxoplasma gondii NEK kinase 0.006 0.0133 0.0406
Schistosoma mansoni ephrin receptor 0.0058 0.0114 0.022
Loa Loa (eye worm) hypothetical protein 0.0288 0.2096 0.2232
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0274 0.0528
Trichomonas vaginalis AGC family protein kinase 0.0358 0.2703 1
Echinococcus multilocularis SH2 motif 0.0051 0.0052 0.0031
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0276 0.1992 0.1971
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0422 0.3255 0.3472
Echinococcus multilocularis protein kinase c iota type 0.0351 0.2635 0.3122
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.006 0.0133 0.0444
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0472 0.3686 0.4379
Schistosoma mansoni tyrosine kinase 0.0252 0.1788 0.3447
Loa Loa (eye worm) hypothetical protein 0.0531 0.4191 0.4474
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0051 0.0052 0.0031
Onchocerca volvulus 0.009 0.0388 0.075
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0205 0.1385 0.1362
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0059 0.0122 0.0235
Loa Loa (eye worm) hypothetical protein 0.072 0.5814 0.6213
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.1046 0.3806
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0148 0.0889 0.1713
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.1098 0.2116
Loa Loa (eye worm) hypothetical protein 0.005 0.0049 0.0039

Activities

Activity type Activity value Assay description Source Reference
EC15 (binding) = 355 nM Inhibition of Aurora B in human NCI-H1229 cells assessed as induction of polyploidy formation after 48 hrs by Hoechst staining-based fluorescence analysis ChEMBL. 22465635
ED50 (functional) = 1.1 mg kg-1 In vivo inhibition of KDR in po dosed mouse assessed as estradiol-induced uterine edema ChEMBL. 22465635
IC50 (binding) = 25 nM Inhibition of KDR using 1 mM ATP by HTRF assay ChEMBL. 22465635
IC50 (binding) = 177 nM Inhibition of Aurora B using 1 mM ATP by HTRF assay ChEMBL. 22465635

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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