Detailed information for compound 1644235

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 983.829 | Formula: C34H57N7NaO17P3S
  • H donors: 9 H acceptors: 15 LogP: -0.05 Rotable bonds: 32
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCCCCCC(=C)CC(=O)SCCNC(=O)CCNC(=O)C(C(COP(=O)(OP(=O)(OCC1OC(C(C1OP(=O)(O)[O-])O)n1cnc2c1ncnc2N)O)O)(C)C)O.[Na+]
  • InChi: 1S/C34H58N7O17P3S.Na/c1-5-6-7-8-9-10-11-12-22(2)17-25(43)62-16-15-36-24(42)13-14-37-32(46)29(45)34(3,4)19-55-61(52,53)58-60(50,51)54-18-23-28(57-59(47,48)49)27(44)33(56-23)41-21-40-26-30(35)38-20-39-31(26)41;/h20-21,23,27-29,33,44-45H,2,5-19H2,1,3-4H3,(H,36,42)(H,37,46)(H,50,51)(H,52,53)(H2,35,38,39)(H2,47,48,49);/q;+1/p-1
  • InChiKey: PHDJQBRZHOPJDD-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0029 0.0018 0.0228
Schistosoma mansoni 60S ribosomal protein L21 0.0024 0.001 0.001
Echinococcus granulosus nervana 2 0.0064 0.0076 0.0074
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0026 0.0022
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0035 0.0029 0.0027
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0124 0.0173 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0056 0.0062 0.006
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.001 0.001
Loa Loa (eye worm) cyclin domain-containing protein 0.0057 0.0064 0.0064
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0029 0.0018 0.0012
Loa Loa (eye worm) hypothetical protein 0.0498 0.0782 0.0782
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0071 0.0071
Entamoeba histolytica cyclin, putative 0.0083 0.0107 0.0101
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0018 0.0001 0.0001
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0027 0.0015 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0008 0.0008
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0067 0.008 0.0077
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0173 0.0169
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.005 0.0047
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0006 0.0006
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0397 0.0618 0.0616
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0029 0.0018 0.0303
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.002 0.0004 0.0004
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.1165 0.1868 0.1868
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0051 0.0054 0.1086
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0012 0.0128
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0046 0.0046
Trypanosoma cruzi cyclin 6, putative 0.0083 0.0107 0.0103
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0012
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0029 0.0018 0.0019
Giardia lamblia Hypothetical protein 0.0057 0.0064 0.006
Trichomonas vaginalis cyclins, putative 0.0083 0.0107 0.0103
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0051 0.0054 0.0816
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.005 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus granulosus cyclin dependent kinase 6 0.018 0.0265 0.0263
Brugia malayi CXXC zinc finger family protein 0.0063 0.0073 0.0073
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0039 0.0035 0.6115
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0067 0.008 0.1246
Schistosoma mansoni hypothetical protein 0.1106 0.1772 0.1772
Echinococcus granulosus cation transporting ATPase 13A3 0.0029 0.0018 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Loa Loa (eye worm) phosphatidylinositol kinase 0.0397 0.0618 0.0618
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0026 0.0357
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0005 0.0005
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0056 0.0062 0.0059
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0077 0.0097 0.0094
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0397 0.0618 0.0618
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0397 0.0618 0.0615
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Brugia malayi beta-lactamase 0.0074 0.0092 0.0092
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0109 0.0149 0.0146
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.002 0.0004 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.002 0.0016
Echinococcus granulosus Glutaredoxin protein 5 0.0064 0.0076 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0043 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0397 0.0618 0.0615
Brugia malayi hypothetical protein 0.027 0.041 0.041
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.005 0.0046
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0109 0.0149 0.3139
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0006 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0389 0.0604 0.0604
Trichomonas vaginalis PIKK family atypical protein kinase 0.0397 0.0618 0.0615
Schistosoma mansoni vesicular amine transporter 0.0026 0.0014 0.0014
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0022 0.0008 0.0006
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0397 0.0618 0.0615
Brugia malayi hypothetical protein 0.0298 0.0456 0.0456
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0332 0.0511 0.0508
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0056 0.005
Loa Loa (eye worm) hypothetical protein 0.0083 0.0107 0.0107
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0397 0.0618 0.0615
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Echinococcus multilocularis cyclin b3 0.0057 0.0064 0.0061
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2065 0.3335 0.3332
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.002 0.0004 0.0001
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0047 0.0043
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.005 0.0046
Leishmania major phosphatidylinositol 3-kinase, putative 0.2065 0.3335 0.3332
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0018 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0051 0.0054 0.005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0006 0.0033
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Echinococcus multilocularis 0.0397 0.0618 0.0616
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Schistosoma mansoni zinc finger protein 0.005 0.0053 0.0053
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0029 0.0018 0.0014
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0397 0.0618 0.0615
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0062 0.0073 0.0073
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.1165 0.1868 0.1863
Trypanosoma cruzi target of rapamycin kinase 3 0.4902 0.7956 0.7955
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0066 0.0066
Giardia lamblia Hypothetical protein 0.0397 0.0618 0.0615
Mycobacterium tuberculosis Probable reductase 0.0334 0.0515 0.69
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0029 0.0018 0.0018
Echinococcus multilocularis cation transporting ATPase 13A3 0.0029 0.0018 0.0015
Brugia malayi Pre-SET motif family protein 0.0035 0.0028 0.0027
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.2912 0.4714 0.4712
Trypanosoma cruzi CYC2-like cyclin, putative 0.0083 0.0107 0.0103
Entamoeba histolytica hypothetical protein 0.1165 0.1868 0.1863
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0036 0.003
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis cyclins, putative 0.004 0.0037 0.0033
Plasmodium vivax hypothetical protein 0.0397 0.0618 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.003 0.002 0.002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0073 0.1493
Trichomonas vaginalis PIKK family atypical protein kinase 0.3997 0.6482 0.648
Leishmania major hypothetical protein, conserved 0.0074 0.0092 0.0089
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.003 0.002 0.002
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0109 0.0149 0.2358
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.6157 1 1
Echinococcus granulosus Protein kinase C brain isozyme 0.0035 0.0029 0.0027
Toxoplasma gondii melibiase subfamily protein 0.0117 0.0162 0.0212
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Leishmania major hypothetical protein, conserved 0.0025 0.0012 0.0008
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2065 0.3335 0.3334
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0334 0.0515 0.69
Mycobacterium tuberculosis Conserved hypothetical protein 0.0175 0.0256 0.3399
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0056 0.0846
Onchocerca volvulus 0.0264 0.0402 0.2735
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0004 0.0001
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0109 0.0149 0.0149
Plasmodium vivax SET domain protein, putative 0.0035 0.0028 0.0385
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.002 0.0004 0.0006
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0029 0.0018 0.0303
Plasmodium falciparum cGMP-dependent protein kinase 0.0022 0.0008 0.0067
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0173 0.0169
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Brugia malayi hypothetical protein 0.0025 0.0012 0.0011
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0092 0.1195
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.01 0.0134 0.0134
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.005 0.0046
Echinococcus granulosus 6 phosphofructokinase 0.0124 0.0173 0.0171
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0061 0.006
Echinococcus multilocularis serine:threonine protein kinase N2 0.0035 0.0029 0.0026
Schistosoma mansoni cpg binding protein 0.0063 0.0073 0.0073
Echinococcus multilocularis cyclin dependent kinase 6 0.018 0.0265 0.0262
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.009 0.0118 0.0116
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0029 0.0018 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0767 0.1221 0.1218
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0092 0.1195
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Trichomonas vaginalis fk506-binding protein, putative 0.0109 0.0149 0.0145
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0031 0.0367
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.09 0.1438 0.1436
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0265 0.0265
Brugia malayi Cyclic-nucleotide gated cation channel 0.003 0.002 0.0019
Echinococcus granulosus cGMP dependent protein kinase 1 0.0022 0.0008 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.005 0.005
Echinococcus granulosus serine protein kinase ATM 0.1165 0.1868 0.1866
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0029 0.0018 0.0189
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0029 0.0018 0.0303
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.2065 0.3335 0.3333
Trichomonas vaginalis cyclins, putative 0.0083 0.0107 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.0165 0.024 0.024
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0397 0.0618 0.0616
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0397 0.0618 0.0615
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.017 0.017
Echinococcus granulosus dna polymerase kappa 0.0021 0.0006 0.0004
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.6157 1 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0176 0.0176
Entamoeba histolytica protein kinase, putative 0.0035 0.0029 0.0023
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Trypanosoma cruzi cyclin, putative 0.0083 0.0107 0.0103
Trypanosoma brucei target of rapamycin kinase 3, putative 0.4902 0.7956 0.7955
Onchocerca volvulus 0.0052 0.0056 0.0363
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0162 0.0162
Brugia malayi Protein kinase domain containing protein 0.0106 0.0145 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.6157 1 1
Schistosoma mansoni cpg binding protein 0.0073 0.009 0.009
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0397 0.0618 0.0616
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0141 0.0201 0.0198
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0029 0.0018 0.0017
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.002 0.0004 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.005 0.0046
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0134 0.019 0.019
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0005 0.0003
Echinococcus multilocularis copper transporting ATPase 1 0.0029 0.0018 0.0015
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0397 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0035 0.0029 0.0026
Leishmania major cyclin 0.0083 0.0107 0.0103
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0051 0.0054 1
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0397 0.0618 0.0616
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Mycobacterium tuberculosis Conserved protein 0.0074 0.0092 0.1195
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0162 0.0162
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.002 0.0004 0.0003
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0029 0.0018 0.0014
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0332 0.0511 0.0508
Echinococcus granulosus serine:threonine protein kinase SMG1 0.1165 0.1868 0.1866
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.002 0.0021
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.005 0.0062
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0004 0.0004
Echinococcus multilocularis survival motor neuron protein 1 0.027 0.041 0.0408
Plasmodium vivax acyl-CoA synthetase, putative 0.0039 0.0035 0.0499
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0029 0.0018 0.0303
Loa Loa (eye worm) hypothetical protein 0.0915 0.1461 0.1461
Schistosoma mansoni atypical protein kinase C 0.0035 0.0029 0.0029
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0109 0.0149 0.0145
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0051 0.0054 0.1086
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.002 0.0004 0.0001
Treponema pallidum NADH oxidase 0.0051 0.0054 0.2964
Brugia malayi beta-lactamase family protein 0.0074 0.0092 0.0092
Leishmania major P-type H -ATPase, putative 0.0029 0.0018 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0389 0.0604 0.0602
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0035 0.0664
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0029 0.0018 0.0303
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0029 0.0018 0.0017
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0397 0.0618 0.0615
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0004 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0092 0.0089
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0051 0.0054 0.0816
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.003 0.002 0.0017
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0151 0.0218 0.0215
Echinococcus multilocularis microtubule associated protein 2 0.0764 0.1217 0.1214
Brugia malayi PHD-finger family protein 0.002 0.0003 0.0002
Trypanosoma cruzi P-type H+-ATPase, putative 0.0029 0.0018 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Echinococcus multilocularis protein kinase c iota type 0.0035 0.0029 0.0026
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.005 0.005
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0109 0.0149 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.332 0.5378 0.5376
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0397 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.09 0.1438 0.1438
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0036 0.0032
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0062 0.0073 0.093
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0051 0.0054 0.0816
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0052 0.0056 0.1127
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0029 0.0018 0.0018
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.2065 0.3335 0.3335
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Plasmodium falciparum protein kinase 5 0.0048 0.005 0.0743
Mycobacterium ulcerans 6-phosphofructokinase 0.0124 0.0173 0.3662
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0056 0.0702
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0044 0.0043 0.0042
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0397 0.0618 0.0618
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0157 0.0227 0.0223
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0029 0.0018 0.0014
Onchocerca volvulus 0.0915 0.1461 1
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0029 0.0018 0.0017
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0173 0.0173
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0006 0.0002
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0026 0.0357
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0067 0.008 0.1246
Trichomonas vaginalis PIKK family atypical protein kinase 0.3643 0.5904 0.5903
Entamoeba histolytica protein kinase, putative 0.01 0.0134 0.0128
Echinococcus granulosus copper transporting ATPase 1 0.0029 0.0018 0.0015
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0028 0.0025
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0109 0.0149 0.0146
Schistosoma mansoni lozenge 0.0115 0.0158 0.0158
Leishmania major DNA polymerase eta, putative 0.0035 0.0028 0.0024
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0083 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.005 0.0046
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0047 0.0043
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0029 0.0018 0.0014
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1165 0.1868 0.1865
Brugia malayi jmjC domain containing protein 0.0097 0.013 0.0129
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0109 0.0149 0.0145
Echinococcus multilocularis hyperpolarization activated cyclic 0.003 0.002 0.0017
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0389 0.0604 0.0604
Echinococcus granulosus protein kinase c iota type 0.0035 0.0029 0.0027
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0173 0.0167
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0098 0.0098
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0056 0.0055
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0199 0.0296 0.0293
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0227 0.0223
Onchocerca volvulus 0.0397 0.0618 0.422
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0334 0.0515 0.8323
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0029 0.0018 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0036 0.0032
Echinococcus multilocularis serine:threonine protein kinase N2 0.0035 0.0029 0.0026
Echinococcus multilocularis cation transporting atpase worm 0.0029 0.0018 0.0015
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0397 0.0618 0.0616
Entamoeba histolytica hypothetical protein 0.0397 0.0618 0.0612
Echinococcus granulosus cation transporting atpase worm 0.0029 0.0018 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Brugia malayi Bromodomain containing protein 0.0125 0.0176 0.0175
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0109 0.0149 0.2358
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0067 0.008 0.0077
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0004 0.0004
Loa Loa (eye worm) bromodomain containing protein 0.0058 0.0066 0.0066
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0117 0.0162 0.0159
Leishmania major hypothetical protein, conserved 0.005 0.0053 0.0049
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0397 0.0618 0.0616
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0098 0.0098
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0397 0.0618 0.0615
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0117 0.0162 0.0159
Onchocerca volvulus 0.0035 0.0028 0.0168
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0056 0.0846
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0012 0.0008
Mycobacterium tuberculosis Conserved protein 0.0074 0.0092 0.1195
Leishmania major protein kinase, putative 0.0022 0.0008 0.0004
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0109 0.0149 0.0149
Onchocerca volvulus 0.0063 0.0073 0.0483
Schistosoma mansoni voltage-gated potassium channel 0.003 0.002 0.002
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0012
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0073 0.007
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0151 0.0218 0.0215
Giardia lamblia Phosphatidylinositol 4-kinase 0.0397 0.0618 0.0615
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0092 0.0089
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0029 0.0018 0.0015
Giardia lamblia DINP protein human, muc B family 0.0021 0.0006 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0036 0.0032
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.003 0.002 0.002
Leishmania major protein kinase, putative 0.0022 0.0008 0.0004
Echinococcus granulosus cyclin dependent kinase 0.0048 0.005 0.0047
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.005 0.005
Brugia malayi Protein kinase domain containing protein 0.0035 0.0029 0.0028
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0029 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.6157 1 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0051 0.0054 0.0053
Brugia malayi hypothetical protein 0.0029 0.0018 0.0017
Brugia malayi Cyclin, N-terminal domain containing protein 0.0083 0.0107 0.0106
Trypanosoma brucei ISWI complex protein 0.005 0.0053 0.0049
Loa Loa (eye worm) PHD-finger family protein 0.0068 0.0081 0.0081
Trypanosoma cruzi trypanothione reductase, putative 0.0146 0.021 0.0206
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.6157 1 1
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0029 0.0018 0.0015
Leishmania major trypanothione reductase 0.0146 0.021 0.0206
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0039 0.0036
Leishmania major proton motive ATPase, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) AGC/AKT protein kinase 0.0106 0.0145 0.0145
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0232 0.035 0.035
Brugia malayi Na,K-ATPase alpha subunit 0.0029 0.0018 0.0017
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0389 0.0604 0.0601
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0036 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Brugia malayi Muscleblind-like protein 0.0498 0.0782 0.0781
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0029 0.0018 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0064 0.006
Schistosoma mansoni cyclin B3 0.0057 0.0064 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Entamoeba histolytica hypothetical protein 0.0397 0.0618 0.0612
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0008 0.0008
Loa Loa (eye worm) AGC/NDR protein kinase 0.0035 0.0029 0.0029
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.002 0.0004 0.0004
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.002 0.0004 0.0004
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0298 0.0456 0.0456
Brugia malayi Cyclin, N-terminal domain containing protein 0.0083 0.0107 0.0106
Echinococcus granulosus cpg binding protein 0.0073 0.009 0.0087
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0035 0.0029 0.0026
Brugia malayi Thioredoxin reductase 0.0146 0.021 0.0209
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0035 0.0029 0.0029
Echinococcus multilocularis muscleblind protein 1 0.0498 0.0782 0.0779
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Toxoplasma gondii AGC kinase 0.01 0.0134 0.0175
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.003 0.002 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0092 0.0089
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0097 0.0097
Brugia malayi Egg laying defective protein 4 0.0022 0.0008 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0029 0.0018 0.0019
Leishmania major hypothetical protein, unknown function 0.0397 0.0618 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0029 0.0018 0.0189
Brugia malayi hypothetical protein 0.0166 0.0242 0.0241
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0029 0.0018 0.0018
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0029 0.0018 0.0012
Echinococcus granulosus cyclic nucleotide gated cation channel 0.003 0.002 0.0018
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.6157 1 1
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0064 0.0076 0.0074
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0014
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0371 0.0576 0.7719
Loa Loa (eye worm) FKBP5 protein 0.0109 0.0149 0.0149
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0397 0.0618 0.0615
Schistosoma mansoni similar to Protein C20orf152 homolog 0.002 0.0004 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0092 0.0092
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0033 0.0025 0.0021
Schistosoma mansoni glutaminase 0.0303 0.0466 0.0466
Echinococcus granulosus cGMP dependent protein kinase 1 0.0022 0.0008 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0092 0.0089
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0036 0.0036
Leishmania major hypothetical protein, conserved 0.0397 0.0618 0.0615
Giardia lamblia G2/mitotic-specific cyclin B 0.0083 0.0107 0.0103
Brugia malayi Protein kinase domain containing protein 0.0048 0.005 0.0049
Brugia malayi PHD-finger family protein 0.003 0.002 0.0019
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0029 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0033
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.002 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0055 0.0061 0.0061
Schistosoma mansoni immunophilin 0.0109 0.0149 0.0149
Schistosoma mansoni atpase class VI type 11c 0.0029 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis cyclin B3 1 0.0057 0.0064 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.6157 1 1
Loa Loa (eye worm) PHD-finger family protein 0.003 0.002 0.002
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0397 0.0618 0.0615
Schistosoma mansoni hypothetical protein 0.09 0.1438 0.1438
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0047 0.0043
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0073 0.1493
Loa Loa (eye worm) hypothetical protein 0.0052 0.0056 0.0056
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Loa Loa (eye worm) hypothetical protein 0.0052 0.0056 0.0056
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0162 0.0162
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0006 0.0002
Leishmania major calcium-translocating P-type ATPase 0.0029 0.0018 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0173 0.0169
Schistosoma mansoni cellular tumor antigen P53 0.011 0.015 0.015
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.6157 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0031 0.0367
Loa Loa (eye worm) hypothetical protein 0.0166 0.0242 0.0242
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0051 0.0054 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0047 0.0043
Mycobacterium ulcerans beta-lactamase 0.0074 0.0092 0.1919
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0036 0.0437
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.002 0.0004 0.0001
Echinococcus granulosus fetal alzheimer antigen falz 0.0077 0.0097 0.0095
Onchocerca volvulus 0.0083 0.0107 0.0712
Echinococcus multilocularis cyclin B 0.0083 0.0107 0.0104
Schistosoma mansoni ap endonuclease 0.004 0.0036 0.0036
Schistosoma mansoni eyes absent homolog 0.0298 0.0456 0.0456
Loa Loa (eye worm) hypothetical protein 0.0298 0.0456 0.0456
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0029 0.0018 0.0303
Entamoeba histolytica hypothetical protein 0.0397 0.0618 0.0612
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.002 0.0004 0.0003
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0073 0.0091 0.0087
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0054 0.005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0118 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Mycobacterium tuberculosis Conserved protein 0.0074 0.0092 0.1195
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.005 0.0046
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0051 0.0054 0.1086
Echinococcus multilocularis patatin phospholipase domain containing protein 0.002 0.0004 0.0001
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0064 0.0076 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.3679 0.5964 0.5962
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.002 0.002
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0029 0.0018 0.0019
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0334 0.0515 0.69
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0023 0.0021
Schistosoma mansoni hypothetical protein 0.0038 0.0033 0.0033
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0036 0.0033
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1165 0.1868 0.1868
Brugia malayi p70 ribosomal S6 kinase beta 0.01 0.0134 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Echinococcus granulosus nervana 2 0.0064 0.0076 0.0074
Entamoeba histolytica PH domain containing protein kinase, putative 0.0073 0.0091 0.0085
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0109 0.0149 0.0143
Toxoplasma gondii histone lysine methyltransferase SET1 0.0128 0.0179 0.0236
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0029 0.0018 0.0303
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0371 0.0576 0.9311
Trypanosoma cruzi ISWI complex protein 0.005 0.0053 0.0049
Trichomonas vaginalis set domain proteins, putative 0.0264 0.0402 0.0398
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Schistosoma mansoni DNA polymerase eta 0.005 0.0052 0.0052
Plasmodium falciparum thioredoxin reductase 0.0146 0.021 0.3351
Onchocerca volvulus 0.002 0.0004 0.0006
Trypanosoma cruzi P-type H+-ATPase, putative 0.0029 0.0018 0.0014
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0397 0.0618 0.0616
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2065 0.3335 0.3332
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Entamoeba histolytica protein kinase rad3, putative 0.1165 0.1868 0.1863
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0109 0.0149 0.0145
Trichomonas vaginalis cyclin B3, putative 0.0057 0.0064 0.006
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.6157 1 1
Toxoplasma gondii P-type ATPase PMA1 0.0029 0.0018 0.0019
Schistosoma mansoni fkbp-rapamycin associated protein 0.1165 0.1868 0.1868
Giardia lamblia Cyclin A 0.0057 0.0064 0.006
Toxoplasma gondii P-type ATPase4, putative 0.0029 0.0018 0.0019
Schistosoma mansoni serine/threonine kinase 0.0035 0.0029 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0173 0.0169
Plasmodium vivax thioredoxin reductase, putative 0.0146 0.021 0.3351
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.1165 0.1868 0.1865
Trichomonas vaginalis PIKK family atypical protein kinase 0.0767 0.1221 0.1218
Loa Loa (eye worm) hypothetical protein 0.009 0.0118 0.0118
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.005 0.0046
Leishmania major mitochondrial DNA polymerase beta 0.0332 0.0511 0.0508
Loa Loa (eye worm) phosphofructokinase 0.0124 0.0173 0.0173
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0109 0.0149 0.0145
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0003 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0031 0.0367
Echinococcus granulosus muscleblind protein 0.0498 0.0782 0.078
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0029 0.0018 0.0018
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0043 0.0043
Echinococcus granulosus serine/threonine protein kinase 0.0073 0.0091 0.0089
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0029 0.0018 0.0017
Echinococcus multilocularis nervana 2 0.0064 0.0076 0.0073
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0397 0.0618 0.0616
Trichomonas vaginalis PIKK family atypical protein kinase 0.3643 0.5904 0.5903
Giardia lamblia Kinase, CMGC CDK 0.0048 0.005 0.0046
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0397 0.0618 0.0618
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0397 0.0618 1
Echinococcus multilocularis serine threonine protein kinase 0.0035 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Mycobacterium ulcerans hypothetical protein 0.0074 0.0092 0.1919
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.005 0.0047
Onchocerca volvulus 0.0397 0.0618 0.422
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0117 0.0162 0.0159
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0056 0.0055
Schistosoma mansoni zinc finger protein 0.0068 0.0082 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.003 0.002 0.0017
Trypanosoma brucei unspecified product 0.0021 0.0006 0.0002
Toxoplasma gondii cation-transporting atpase family protein 0.0029 0.0018 0.0019
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0109 0.0149 0.0148
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Echinococcus granulosus peregrin 0.0038 0.0032 0.003
Trichomonas vaginalis conserved hypothetical protein 0.09 0.1438 0.1434
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Plasmodium vivax cation transporting ATPase, putative 0.0029 0.0018 0.0228
Brugia malayi E1-E2 ATPase family protein 0.0029 0.0018 0.0017
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0006 0.0006
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.002 0.0017
Trichomonas vaginalis glutathione reductase, putative 0.0051 0.0054 0.005
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.005 0.005
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0332 0.0511 0.0508
Echinococcus multilocularis Zinc finger, PHD finger 0.0397 0.0618 0.0616
Leishmania major fk506-binding protein 1-like protein 0.0109 0.0149 0.0145
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0006 0.0004
Plasmodium falciparum glutathione reductase 0.0146 0.021 0.3351
Brugia malayi E1-E2 ATPase family protein 0.0029 0.0018 0.0017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1165 0.1868 0.1868
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.005 0.0046
Brugia malayi 6-phosphofructokinase 0.0124 0.0173 0.0172
Loa Loa (eye worm) hypothetical protein 0.0051 0.0054 0.0054
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0109 0.0149 0.0145
Brugia malayi glutaminase DH11.1 0.0303 0.0466 0.0465
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0052 0.0056 0.1127
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0006 0.0003
Entamoeba histolytica cyclin family protein 0.0057 0.0064 0.0058
Loa Loa (eye worm) hypothetical protein 0.0052 0.0056 0.0056
Plasmodium vivax glutathione reductase, putative 0.0146 0.021 0.3351
Entamoeba histolytica protein kinase, putative 0.0106 0.0145 0.0138
Brugia malayi hypothetical protein 0.0915 0.1461 0.1461
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0109 0.0149 0.0145
Trichomonas vaginalis immunophilin, putative 0.0109 0.0149 0.0145
Trichomonas vaginalis cyclin B, putative 0.0083 0.0107 0.0103
Brugia malayi cell division control protein 2 homolog 0.0048 0.005 0.0049
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.003 0.002 0.0018
Echinococcus multilocularis Glutaredoxin protein 5 0.0064 0.0076 0.0073
Brugia malayi beta-lactamase family protein 0.0074 0.0092 0.0092
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0051 0.0054 1
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0397 0.0618 0.0618
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.005 0.0047
Giardia lamblia Kinase, CMGC CDK 0.0048 0.005 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0056 0.1127
Brugia malayi phosphofructokinase 0.0124 0.0173 0.0172
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0397 0.0618 0.0615
Echinococcus multilocularis serine protein kinase ATM 0.1165 0.1868 0.1866
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0397 0.0618 1
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0397 0.0618 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0334 0.0515 0.69
Trichomonas vaginalis cyclin D, putative 0.0057 0.0064 0.006
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0029 0.0018 0.0014
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0612
Brugia malayi Protein kinase domain containing protein 0.0035 0.0029 0.0028
Loa Loa (eye worm) thioredoxin reductase 0.0146 0.021 0.021
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0092 0.009
Trypanosoma cruzi cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0141 0.0201 0.0198
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.6157 1 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.005 0.0047
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.002 0.0004 0.0004
Echinococcus granulosus microtubule associated protein 2 0.0764 0.1217 0.1214
Schistosoma mansoni cpg binding protein 0.0073 0.009 0.009
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0397 0.0618 0.0612
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1165 0.1868 0.1865
Schistosoma mansoni phosphoserine phosphatase 0.0029 0.0018 0.0018
Echinococcus multilocularis thioredoxin glutathione reductase 0.0146 0.021 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.1298 0.2085 0.2082
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.003 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0397 0.0618 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.413 0.6698 0.6697
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0035 0.0029 0.0027
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0029 0.0018 0.0019
Trichomonas vaginalis cyclins, putative 0.0083 0.0107 0.0103
Schistosoma mansoni ATPase 0.0029 0.0018 0.0018
Toxoplasma gondii target of rapamycin (TOR), putative 0.4579 0.743 1
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.002 0.0004 0.0004
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.005 0.0047
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0092 0.1195
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1298 0.2085 0.2802
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Trypanosoma brucei DNA polymerase eta, putative 0.005 0.0052 0.0049
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0036 0.0032
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0012 0.0008
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.005 0.0046
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0029 0.0018 0.0019
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0026 0.003
Loa Loa (eye worm) hypothetical protein 0.0133 0.0189 0.0189
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0092 0.1442
Leishmania major phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0035 0.0029 0.0027
Trypanosoma brucei rac serine-threonine kinase, putative 0.0106 0.0145 0.0141
Leishmania major DNA polymerase eta, putative 0.005 0.0052 0.0049
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0012 0.0128
Echinococcus granulosus zinc finger protein 0.0068 0.0082 0.0079
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0118 0.0163 0.016
Brugia malayi follicle stimulating hormone receptor 0.0265 0.0403 0.0402
Loa Loa (eye worm) hypothetical protein 0.0094 0.0124 0.0124
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0029 0.0018 0.0012
Onchocerca volvulus 0.0055 0.0061 0.0397
Schistosoma mansoni hypothetical protein 0.0068 0.0081 0.0081
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0397 0.0618 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.2065 0.3335 0.3332
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0046 0.0046
Loa Loa (eye worm) phosphatidylinositol 3 0.2065 0.3335 0.3335
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0057 0.0064 0.0061
Mycobacterium ulcerans lipase LipD 0.0074 0.0092 0.1919
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.027 0.041 0.041
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0029 0.0018 0.0189
Trypanosoma cruzi DNA polymerase eta, putative 0.005 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.1165 0.1868 0.1868
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0035 0.0029 0.0029
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0162 0.0162
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0051 0.0054 0.005
Schistosoma mansoni serine/threonine-protein kinase 0.0073 0.0091 0.0091
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.002 0.0004 0.0004
Brugia malayi N-terminal motif family protein 0.002 0.0004 0.0003
Schistosoma mansoni bromodomain containing protein 0.0211 0.0315 0.0315
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0012 0.0011
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0051 0.0054 0.0052
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.0232 0.0348 0.0348
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0018 0.0012
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0061 0.0061
Loa Loa (eye worm) E1-E2 ATPase 0.0029 0.0018 0.0018
Echinococcus granulosus hyperpolarization activated cyclic 0.003 0.002 0.0018
Giardia lamblia Copper-transporting P-type ATPase 0.0029 0.0018 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.3325 0.5386 0.5385
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0265 0.0403 0.0403
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0029 0.0018 0.0014
Brugia malayi MH2 domain containing protein 0.0122 0.017 0.0169
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0397 0.0618 0.0618
Leishmania major phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Plasmodium falciparum copper-transporting ATPase 0.0029 0.0018 0.0228
Toxoplasma gondii FATC domain-containing protein 0.1165 0.1868 0.251
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0029 0.0018 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0092 0.1195
Brugia malayi Pre-SET motif family protein 0.0232 0.035 0.0349
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0397 0.0618 0.0618
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0035 0.0029 0.0026
Onchocerca volvulus 0.0074 0.0092 0.0613
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.002 0.0004 0.0004
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0036 0.1915
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0028 0.0028
Schistosoma mansoni immunophilin 0.0094 0.0124 0.0124
Echinococcus multilocularis cation transporting ATPase 13A1 0.0029 0.0018 0.0015
Brugia malayi protein kinase C II. 0.0035 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0045 0.0045 0.0045
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.0043 0.004
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Brugia malayi Bromodomain containing protein 0.0249 0.0377 0.0376
Trichomonas vaginalis cyclin B, putative 0.0057 0.0064 0.006
Echinococcus granulosus protein kinase c epsilon type 0.0035 0.0029 0.0027
Toxoplasma gondii exonuclease III APE 0.004 0.0036 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0092 0.0089
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0006 0.0052
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.6157 1 1
Echinococcus granulosus cyclin B3 1 0.0057 0.0064 0.0061
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0092 0.1195
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0056 0.0052
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0397 0.0618 0.0616
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0389 0.0604 0.0602
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0083 0.0107 0.0103
Brugia malayi glutathione reductase 0.0146 0.021 0.0209
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0031 0.003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0146 0.021 0.2779
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0151 0.0218 0.0218
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0334 0.0515 0.69
Schistosoma mansoni cation-transporting atpase worm 0.0029 0.0018 0.0018
Schistosoma mansoni cation-transporting atpase worm 0.0029 0.0018 0.0018
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0124 0.0173 0.2751
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0051 0.0054 0.005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0397 0.0618 0.0618
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0092 0.1195
Echinococcus multilocularis protein kinase c epsilon type 0.0035 0.0029 0.0026
Echinococcus granulosus dna polymerase eta 0.005 0.0052 0.005
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0026 0.1298
Trichomonas vaginalis AGC family protein kinase 0.0042 0.004 0.0036
Echinococcus granulosus voltage gated potassium channel 0.0044 0.0043 0.004
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0397 0.0618 0.0615
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0397 0.0618 0.0615
Trichomonas vaginalis cyclin D, putative 0.0057 0.0064 0.006
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0012 0.0008
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0029 0.0018 0.0014
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.002 0.002
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.005 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0397 0.0618 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0475 0.0745 1
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0092 0.1919
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.002 0.0004 0.0004
Echinococcus multilocularis peregrin 0.0038 0.0032 0.0029
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.005 0.0043
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0056 0.0052
Echinococcus granulosus protein kinase C gamma type 0.0035 0.0029 0.0027
Echinococcus granulosus phospholipid transporting ATPase VA 0.0029 0.0018 0.0015
Echinococcus granulosus cyclin b3 0.0057 0.0064 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0173 0.0169
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0094 0.0124 0.0121
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.002 0.0004 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.1165 0.1868 0.1865
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0397 0.0618 0.0616
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Giardia lamblia PHD finger protein 15 0.003 0.002 0.0016
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0036 0.0036
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.003 0.002 0.0018
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0029 0.0018 0.0015
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0397 0.0618 0.0615
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.1165 0.1868 0.1866
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0064 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Toxoplasma gondii hypothetical protein 0.0043 0.0041 0.0051
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0109 0.0149 0.0145
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.4902 0.7956 0.7955
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0073 0.007
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0397 0.0618 0.0616
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0029 0.0018 0.0189
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0005 0.0002
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0029 0.0018 0.0228
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0029 0.0018 0.0015
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.2065 0.3335 0.3332
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0022 0.0008 0.0005
Brugia malayi Cyclin, N-terminal domain containing protein 0.0057 0.0064 0.0063
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0039 0.0036
Echinococcus multilocularis Protein lozenge 0.0115 0.0158 0.0155
Toxoplasma gondii hypothetical protein 0.0053 0.0058 0.0073
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Entamoeba histolytica cyclin, putative 0.0057 0.0064 0.0058
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.0056 0.1127
Mycobacterium ulcerans hypothetical protein 0.0052 0.0056 0.1127
Onchocerca volvulus 0.002 0.0004 0.0006
Echinococcus multilocularis zinc finger protein 0.0068 0.0082 0.0079
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0026 0.002
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0092 0.0092
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Leishmania major ATP-dependent phosphofructokinase 0.0124 0.0173 0.0169
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Trichomonas vaginalis cyclins, putative 0.0057 0.0064 0.006
Plasmodium vivax protein kinase Crk2 0.0048 0.005 0.0743
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0029 0.0018 0.0303
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0031 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.3325 0.5386 0.5385
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.005 0.005
Schistosoma mansoni microtubule-associated protein tau 0.0764 0.1217 0.1217
Schistosoma mansoni cyclin B 0.0083 0.0107 0.0107
Echinococcus granulosus survival motor neuron protein 1 0.027 0.041 0.0408
Plasmodium vivax copper-transporting ATPase, putative 0.0029 0.0018 0.0228
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0389 0.0604 0.0604
Plasmodium vivax calcium-transporting ATPase, putative 0.0029 0.0018 0.0228
Echinococcus granulosus cGMP dependent protein kinase 0.0022 0.0008 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0036 0.0032
Echinococcus multilocularis geminin 0.1106 0.1772 0.177
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0029 0.0018 0.0303
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0397 0.0618 1
Plasmodium vivax P-type ATPase4, putative 0.0029 0.0018 0.0228
Schistosoma mansoni serine/threonine-protein kinase 0.0073 0.0091 0.0091
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0094 0.0124 0.0122
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.005 0.0046
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Brugia malayi jmjC domain containing protein 0.0046 0.0046 0.0045
Entamoeba histolytica hypothetical protein 0.0397 0.0618 0.0612
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0015 0.0015
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0397 0.0618 0.0827
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.6157 1 1
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0054 0.005
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0397 0.0618 0.0615
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0118 0.0163 0.0161
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0029 0.0018 0.0014
Schistosoma mansoni hypothetical protein 0.1106 0.1772 0.1772
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0022 0.0008 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Echinococcus granulosus serine threonine protein kinase nrc 0.0067 0.008 0.0078
Echinococcus granulosus cyclin B 0.0083 0.0107 0.0104
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0026 0.0357
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0061 0.0061
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0029 0.0018 0.0014
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0051 0.0054 0.0816
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0026 0.4378
Loa Loa (eye worm) glutathione reductase 0.0146 0.021 0.021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0056 0.005
Echinococcus granulosus serine:threonine protein kinase N2 0.0035 0.0029 0.0027
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0028 0.0024
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0109 0.0149 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.1652 0.2662 0.2659
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0227 0.0223
Entamoeba histolytica cyclin family protein 0.0057 0.0064 0.0058
Trichomonas vaginalis mercuric reductase, putative 0.0051 0.0054 0.005
Loa Loa (eye worm) jmjC domain-containing protein 0.0046 0.0046 0.0046
Echinococcus granulosus histone lysine methyltransferase setb 0.009 0.0118 0.0116
Leishmania major phosphatidylinositol kinase related protein, putative 0.0397 0.0618 0.0615
Echinococcus granulosus NDR protein kinase 0.0035 0.0029 0.0027
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0118 0.0118
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0039 0.0035 0.0413
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0397 0.0618 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0037 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0061
Toxoplasma gondii ABC1 family protein 0.0074 0.0092 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0029 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0056 0.1127
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0054 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0035 0.0029 0.0029
Trypanosoma brucei cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0026 0.0022
Trypanosoma brucei P-type H+-ATPase, putative 0.0029 0.0018 0.0014
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0092 0.1442
Schistosoma mansoni methyl-cpg binding protein mbd 0.0056 0.0062 0.0062
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0767 0.1221 0.1218
Loa Loa (eye worm) hypothetical protein 0.0044 0.0043 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Trichomonas vaginalis cyclins, putative 0.0083 0.0107 0.0103
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0109 0.0149 0.0143
Trypanosoma brucei mitotic cyclin 6 0.0083 0.0107 0.0103
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.005 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.3325 0.5386 0.5385
Toxoplasma gondii thioredoxin reductase 0.0146 0.021 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.332 0.5378 0.5376
Loa Loa (eye worm) hypothetical protein 0.0039 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.1165 0.1868 0.1865
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.2065 0.3335 0.3333
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0029 0.0018 0.0012
Echinococcus granulosus cyclins 0.0057 0.0064 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0026 0.0022
Echinococcus granulosus hyperpolarization activated cyclic 0.003 0.002 0.0018
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0173 0.0173
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0029 0.0018 0.0015
Echinococcus granulosus lysine specific demethylase 5A 0.0046 0.0046 0.0044
Mycobacterium leprae conserved hypothetical protein 0.0397 0.0618 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.003 0.002 0.0017
Echinococcus multilocularis voltage gated potassium channel 0.0044 0.0043 0.004
Leishmania major DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0028 0.0028
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0051 0.0054 0.0054
Echinococcus granulosus geminin 0.1106 0.1772 0.177
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0109 0.0149 0.0145
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0397 0.0618 0.0615
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0026 0.0357
Brugia malayi Melibiase family protein 0.0078 0.0098 0.0097
Trichomonas vaginalis esterase, putative 0.0074 0.0092 0.0089
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0173 0.0173
Echinococcus multilocularis cpg binding protein 0.0073 0.009 0.0087
Echinococcus multilocularis rac serine:threonine kinase 0.0073 0.0091 0.0088
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0006 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.4579 0.743 0.7429
Giardia lamblia GTOR 0.6157 1 1
Plasmodium falciparum thioredoxin reductase 0.0051 0.0054 0.0816
Leishmania major peptidylprolyl isomerase-like protein 0.0109 0.0149 0.0145
Echinococcus granulosus tumor protein p63 0.0751 0.1194 0.1192
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0054 0.005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0389 0.0604 0.0601
Loa Loa (eye worm) hypothetical protein 0.0767 0.1221 0.1221
Trichomonas vaginalis cyclin A, putative 0.0083 0.0107 0.0103
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0057 0.0064 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0029 0.0025
Loa Loa (eye worm) runx1 0.0115 0.0158 0.0158
Brugia malayi PHD-finger family protein 0.0085 0.011 0.0109
Giardia lamblia Kinase, AGC PKA 0.0067 0.008 0.0077
Schistosoma mansoni ATPase 0.0029 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.3679 0.5964 0.5962
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0051 0.0054 0.0051
Mycobacterium tuberculosis Probable oxidoreductase 0.0371 0.0576 0.7719
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0051 0.0054 0.0676
Echinococcus multilocularis muscleblind protein 0.0498 0.0782 0.0779
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0109 0.0149 0.0145
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0051 0.0054 0.0067
Trypanosoma cruzi copper-transporting ATPase, putative 0.0029 0.0018 0.0014
Plasmodium falciparum phd finger protein, putative 0.003 0.002 0.026
Entamoeba histolytica protein kinase 2, putative 0.0067 0.008 0.0074
Echinococcus multilocularis cyclins 0.0057 0.0064 0.0061
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Loa Loa (eye worm) glutaminase 0.0303 0.0466 0.0466
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0035 0.0029 0.0029
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0036 0.0032
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0397 0.0618 1
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0029 0.0018 0.0014
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0062 0.0073 0.0069
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0012 0.0128
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0397 0.0618 0.0612
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0173 0.0167
Loa Loa (eye worm) hypothetical protein 0.0035 0.0029 0.0029
Echinococcus granulosus cation transporting ATPase 13A1 0.0029 0.0018 0.0015
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Trichomonas vaginalis glutaminase, putative 0.0303 0.0466 0.0462
Brugia malayi Hr1 repeat family protein 0.0035 0.0029 0.0028
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0397 0.0618 0.0615
Onchocerca volvulus 0.0074 0.0092 0.0613
Leishmania major P-type H -ATPase, putative 0.0029 0.0018 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0056 0.0052
Giardia lamblia NADH oxidase lateral transfer candidate 0.0051 0.0054 0.005
Trichomonas vaginalis AGC family protein kinase 0.0035 0.0029 0.0025
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0051 0.0054 0.005
Echinococcus multilocularis expressed conserved protein 0.0022 0.0008 0.0005
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0036 0.0032
Loa Loa (eye worm) hypothetical protein 0.011 0.015 0.015
Trypanosoma brucei P-type H+-ATPase, putative 0.0029 0.0018 0.0014
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0067 0.008 0.0078
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0006 0.0003
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0029 0.0018 0.0015
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Trypanosoma cruzi cyclin, putative 0.0083 0.0107 0.0103
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0397 0.0618 0.0616
Treponema pallidum cation-transporting ATPase, P-type 0.0029 0.0018 0.0828
Treponema pallidum hypothetical protein 0.0029 0.0018 0.0828
Mycobacterium leprae Probable lipase LipE 0.0074 0.0092 0.1442
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.0043 0.004
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0173 0.0173
Loa Loa (eye worm) phosphatidylinositol 3 0.0397 0.0618 0.0618
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0073 0.0073
Trypanosoma brucei trypanothione reductase 0.0146 0.021 0.0206
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0061 0.0061
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0052 0.0056 0.0702
Trichomonas vaginalis cyclin B, putative 0.0083 0.0107 0.0103
Trichomonas vaginalis cation-transporting ATPase, putative 0.0029 0.0018 0.0014
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0029 0.0018 0.0189
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0054 0.005
Schistosoma mansoni survival motor neuron protein 0.0055 0.0061 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Schistosoma mansoni type V p-type atpase isoform 0.0029 0.0018 0.0018
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.013 0.0128
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.6157 1 1
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0006 0.0002
Echinococcus multilocularis dna polymerase eta 0.005 0.0052 0.0049
Echinococcus granulosus cyclic nucleotide gated cation channel 0.003 0.002 0.0018
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis cyclin B, putative 0.0083 0.0107 0.0103
Plasmodium falciparum glutathione reductase 0.0051 0.0054 0.0816
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0018
Mycobacterium ulcerans glutaminase 0.0303 0.0466 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.2557 0.4137 0.4134
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0092 0.0089
Loa Loa (eye worm) hypothetical protein 0.005 0.0052 0.0052
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.013 0.0127
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0173 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.2065 0.3335 0.3332
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0026 0.4378
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.002 0.0016
Schistosoma mansoni ap endonuclease 0.004 0.0036 0.0036
Trichomonas vaginalis cyclin B, putative 0.0083 0.0107 0.0103
Trypanosoma cruzi proton motive ATPase 1, putative 0.0029 0.0018 0.0014
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0006 0.0006
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0173 0.0169
Loa Loa (eye worm) hypothetical protein 0.0397 0.0618 0.0618
Entamoeba histolytica acyl-coA synthetase, putative 0.0052 0.0056 0.005
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0092 0.0089
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0036 0.0701
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0397 0.0618 0.0616
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0018 0.0015
Echinococcus granulosus patatin phospholipase domain containing protein 0.002 0.0004 0.0001
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0151 0.0218 0.0217
Echinococcus multilocularis fk506 binding protein 0.0109 0.0149 0.0146
Echinococcus multilocularis nervana 2 0.0064 0.0076 0.0073
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0006 0.0002
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0077 0.0097 0.0097
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0397 0.0618 0.0618
Entamoeba histolytica protein kinase, putative 0.0106 0.0145 0.0138
Echinococcus granulosus thioredoxin glutathione reductase 0.0146 0.021 0.0207
Brugia malayi Bromodomain containing protein 0.0038 0.0032 0.0032
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0035 0.0029 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.6157 1 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0092 0.1919
Loa Loa (eye worm) glutaminase 2 0.0303 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0012
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0078 0.0098 0.0094
Loa Loa (eye worm) hypothetical protein 0.0143 0.0205 0.0205
Trypanosoma cruzi Protein kinase B 0.0073 0.0091 0.0087
Onchocerca volvulus Alhambra homolog 0.003 0.002 0.0115
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0109 0.0149 0.8572
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.017 0.017
Onchocerca volvulus 0.011 0.015 0.101
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0397 0.0618 0.0616
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.002 0.0004 0.0004
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.005 0.0043
Schistosoma mansoni cyclins 0.0057 0.0064 0.0064
Brugia malayi ImpB/MucB/SamB family protein 0.005 0.0052 0.0052
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0056 0.1127
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.002
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Trypanosoma cruzi ISWI complex protein 0.005 0.0053 0.0049
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.2065 0.3335 0.3332
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0397 0.0618 0.0615
Schistosoma mansoni cation-transporting ATPase 0.0029 0.0018 0.0018
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0006 0.0033
Loa Loa (eye worm) AGC/PKN protein kinase 0.0035 0.0029 0.0029
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0028 0.0032
Brugia malayi 6-phosphofructokinase 0.0124 0.0173 0.0172
Plasmodium falciparum cyclin 0.0057 0.0064 0.0974
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0029 0.0018 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.332 0.5378 0.5376
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Loa Loa (eye worm) beta-lactamase 0.0074 0.0092 0.0092
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.0131 0.0185 0.0185
Leishmania major copper-transporting ATPase-like protein, putative 0.0029 0.0018 0.0014
Loa Loa (eye worm) calcium ATPase 0.0029 0.0018 0.0018
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0029 0.0018 0.0019
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0029 0.0018 0.0228
Brugia malayi FAT domain containing protein 0.09 0.1438 0.1437
Echinococcus multilocularis 6 phosphofructokinase 0.0124 0.0173 0.017
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0052 0.0056 0.1127
Entamoeba histolytica PH domain containing protein kinase, putative 0.0073 0.0091 0.0085
Chlamydia trachomatis metal transport ATPase 0.0029 0.0018 0.2794
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0092 0.0089
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0029 0.0018 0.0014
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0029 0.0018 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0389 0.0604 0.0604
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0036 0.0527
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0054 0.005
Loa Loa (eye worm) hypothetical protein 0.1298 0.2085 0.2085
Loa Loa (eye worm) hypothetical protein 0.0074 0.0092 0.0092
Mycobacterium tuberculosis Probable dehydrogenase 0.0334 0.0515 0.69
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0092 0.0092
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0029 0.0018 0.0014
Echinococcus multilocularis serine:threonine protein kinase 38 0.0035 0.0029 0.0026
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.003 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0397 0.0618 0.0618
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0109 0.0149 0.0146
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0033 0.0032
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0026 0.003
Onchocerca volvulus 0.0166 0.0242 0.1636
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0026 0.003
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.002 0.0004 0.0001
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0028 0.0033
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0371 0.0576 0.7719
Loa Loa (eye worm) phosphatidylinositol 3 0.6157 1 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0004 0.0001
Plasmodium vivax hypothetical protein, conserved 0.003 0.002 0.026
Schistosoma mansoni hypothetical protein 0.005 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.003 0.002 0.002
Onchocerca volvulus 0.0029 0.0018 0.0102
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0612
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.003 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0078 0.0098 0.0098
Plasmodium falciparum acyl-CoA synthetase 0.0039 0.0035 0.0499
Trichomonas vaginalis PIKK family atypical protein kinase 0.3679 0.5964 0.5962
Schistosoma mansoni immunophilin 0.0109 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0915 0.1461 0.1461
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0389 0.0604 0.0604
Leishmania major phosphatidylinositol 3-kinase, putative 0.0397 0.0618 0.0615
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0008 0.0008
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0073 0.0072
Mycobacterium tuberculosis Conserved hypothetical protein 0.0397 0.0618 0.8291
Loa Loa (eye worm) AGC/PKG protein kinase 0.0022 0.0008 0.0008
Echinococcus multilocularis tumor protein p63 0.0751 0.1194 0.1191
Toxoplasma gondii NADPH-glutathione reductase 0.0051 0.0054 0.0067
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0124 0.0173 0.2281
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0029 0.0018 0.0015
Onchocerca volvulus 0.0074 0.0092 0.0613
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0036 0.0527
Trichomonas vaginalis PIKK family atypical protein kinase 0.5257 0.8534 0.8533
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0397 0.0618 0.0618
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0092 0.0092
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0397 0.0618 0.0615
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0145 0.0141
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.002 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.4897 0.7948 0.7947
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0397 0.0618 0.0615
Schistosoma mansoni copper ABC transporter ATPase 0.0029 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.3325 0.5386 0.5385
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.1165 0.1868 0.1865
Loa Loa (eye worm) hypothetical protein 0.0498 0.0782 0.0782
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0092 0.0089
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.09 0.1438 0.1435
Loa Loa (eye worm) hypothetical protein 0.1255 0.2015 0.2015
Schistosoma mansoni methyl-cpg binding protein mbd 0.0056 0.0062 0.0062
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0092 0.1195
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0199 0.0296 0.0293
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0002
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0037 0.0032 0.0031
Mycobacterium ulcerans hypothetical protein 0.0175 0.0256 0.5457
Schistosoma mansoni voltage-gated potassium channel 0.0165 0.024 0.024

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.501 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.494 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.443 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.29 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.122 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.074 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.004 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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