Detailed information for compound 1783441

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 331.494 | Formula: C24H29N
  • H donors: 0 H acceptors: 0 LogP: 6.57 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN([C@H](c1ccc(cc1)C(C)(C)C)C)Cc1cccc2c1cccc2
  • InChi: 1S/C24H29N/c1-18(19-13-15-22(16-14-19)24(2,3)4)25(5)17-21-11-8-10-20-9-6-7-12-23(20)21/h6-16,18H,17H2,1-5H3/t18-/m0/s1
  • InChiKey: KDQZVKMGGXHOSY-SFHVURJKSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0731 0.2195 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0196 0.0238
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.0132 0.0132
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0089 0.0358
Schistosoma mansoni microtubule-associated protein tau 0.2778 0.8493 0.8493
Echinococcus granulosus Diacylglycerol kinase theta 0.0105 0.0269 0.0269
Mycobacterium ulcerans bacterioferritin BfrA 0.0025 0.0023 0.0027
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0105 0.0269 0.0269
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0042 0.0076 0.0065
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0034 0.0034
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.007 0.0084
Schistosoma mansoni ferritin 0.0025 0.0023 0.0022
Brugia malayi Isocitrate dehydrogenase 0.0047 0.0089 0.0359
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0588 0.1756 0.2126
Brugia malayi Bromodomain containing protein 0.0031 0.0041 0.0164
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Loa Loa (eye worm) MH2 domain-containing protein 0.0032 0.0046 0.0056
Schistosoma mansoni DNA helicase recq5 0.0018 0.0002 0.0002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0021 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0221 0.0221
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0431 0.1272 0.3427
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0051 0.0103 0.0368
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0458 0.0457
Loa Loa (eye worm) norepinephrine transporter 0.0182 0.0508 0.0616
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0042 0.0076 0.0092
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0051 0.0103 0.099
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0186 0.0519 0.2096
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Giardia lamblia Phosphoglycerate kinase 0.0166 0.0458 0.2605
Echinococcus granulosus lysine specific demethylase 6a 0.004 0.007 0.007
Echinococcus multilocularis importin subunit beta 1 0.003 0.0038 0.0038
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0135 0.0362 0.0976
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0117 0.0315
Brugia malayi PHD-finger family protein 0.0028 0.0034 0.0135
Brugia malayi Probable DNA topoisomerase II 0.0186 0.0519 0.2096
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0431 0.1272 0.9803
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0032 0.0046 0.0046
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0186 0.0519 0.0519
Echinococcus granulosus neuropeptide receptor A26 0.0943 0.2847 0.2847
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0458 0.0457
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.0132 0.0531
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Giardia lamblia PHD finger protein 15 0.0028 0.0034 0.019
Schistosoma mansoni coup transcription factor 0.006 0.0132 0.0131
Echinococcus granulosus lysine specific demethylase 5A 0.0165 0.0455 0.0455
Echinococcus multilocularis thyroid hormone receptor alpha 0.006 0.0132 0.0132
Echinococcus granulosus acetylcholinesterase 0.0082 0.0198 0.0198
Schistosoma mansoni jumonji domain containing protein 0.019 0.0531 0.0531
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0117 0.0435
Echinococcus multilocularis musashi 0.0053 0.011 0.011
Entamoeba histolytica hypothetical protein 0.0024 0.0021 0.0018
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0023 0.0018 0.008
Schistosoma mansoni DNA topoisomerase II 0.0186 0.0519 0.0518
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Echinococcus granulosus geminin 0.0838 0.2523 0.2523
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0121 0.0325
Plasmodium vivax basic transcription factor 3b, putative 0.0069 0.0158 0.072
Onchocerca volvulus Ceramide kinase 1 homolog 0.0105 0.0269 0.1815
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0032 0.0074
Entamoeba histolytica transcription factor BTF3, putative 0.0069 0.0158 0.0186
Plasmodium vivax DNA topoisomerase II, putative 0.0186 0.0519 0.2362
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0182 0.0508 0.0616
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.006 0.0132 0.016
Schistosoma mansoni hypothetical protein 0.0081 0.0196 0.0196
Schistosoma mansoni ferritin 0.0025 0.0023 0.0022
Chlamydia trachomatis phosphoglycerate kinase 0.0166 0.0458 0.1933
Schistosoma mansoni heat shock protein 0.0134 0.0357 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Mycobacterium ulcerans glutaminase 0.0821 0.2474 0.3002
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0042 0.0076 0.0076
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0089 0.0081
Trichomonas vaginalis heat shock protein, putative 0.0096 0.0241 0.0922
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0135 0.0362 0.0976
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0117 0.0136
Onchocerca volvulus 0.0031 0.0041 0.0193
Brugia malayi mbt repeat family protein 0.0096 0.024 0.0969
Trypanosoma cruzi heat shock protein 90, putative 0.0134 0.0357 0.0962
Entamoeba histolytica phosphoglycerate kinase, putative 0.0166 0.0458 0.0549
Toxoplasma gondii heat shock protein HSP90 0.0134 0.0357 0.2752
Schistosoma mansoni sodium-dependent amino acid transporter 0.0031 0.0041 0.0041
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Schistosoma mansoni ran 0.0022 0.0014 0.0013
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0057 0.0121 0.012
Plasmodium falciparum metacaspase 1 0.0026 0.0026 0.0117
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0044 0.0044
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0082 0.0198 0.0198
Schistosoma mansoni steroid hormone receptor ad4bp 0.006 0.0132 0.0131
Brugia malayi Smad1 0.0032 0.0046 0.0184
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.006 0.0066
Plasmodium vivax SET domain protein, putative 0.0065 0.0145 0.066
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0054 0.0054
Echinococcus granulosus tumor protein p63 0.0332 0.0967 0.0967
Entamoeba histolytica heat shock protein 90, putative 0.0134 0.0357 0.0427
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0051 0.0103 0.0103
Loa Loa (eye worm) RNA binding protein 0.0063 0.0139 0.0169
Schistosoma mansoni ap endonuclease 0.0056 0.0117 0.0117
Brugia malayi conserved hypotetical protein 0.0028 0.0034 0.0135
Onchocerca volvulus Cell death protein 3 homolog 0.0026 0.0026 0.0083
Loa Loa (eye worm) Smad1 0.0032 0.0046 0.0056
Echinococcus granulosus muscleblind protein 0.0152 0.0413 0.0413
Plasmodium falciparum DNA gyrase subunit B 0.0731 0.2195 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.0034 0.0138
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0034 0.0135
Leishmania major developmentally regulated phosphoprotein-like protein 0.0042 0.0076 0.0205
Entamoeba histolytica hypothetical protein 0.0029 0.0035 0.0036
Loa Loa (eye worm) hypothetical protein 0.0053 0.011 0.0133
Brugia malayi Eye-specific diacylglycerol kinase 0.0105 0.0269 0.1087
Toxoplasma gondii histone lysine methyltransferase SET1 0.0439 0.1297 1
Schistosoma mansoni hypothetical protein 0.0028 0.0034 0.0033
Brugia malayi hypothetical protein 0.0025 0.0022 0.0089
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.0044 0.0044
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0413 0.0413
Echinococcus granulosus peregrin 0.0031 0.0041 0.0041
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0221 0.0221
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Schistosoma mansoni hypothetical protein 0.0838 0.2523 0.2523
Trypanosoma brucei unspecified product 0.0057 0.0121 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.002 0.0026
Trypanosoma brucei glucosidase, putative 0.0037 0.006 0.016
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0041 0.0041
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0044 0.0177
Brugia malayi jmjC domain containing protein 0.0209 0.059 0.2384
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.0132 0.0132
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0105 0.0269 0.0725
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0031 0.0041 0.0041
Schistosoma mansoni retinoic acid receptor RXR 0.006 0.0132 0.0131
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0089 0.0101
Mycobacterium leprae Probable two component sensor kinase MprB 0.0042 0.0076 0.0665
Brugia malayi Nuclear hormone receptor family member nhr-41 0.006 0.0132 0.0531
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.022 0.022
Brugia malayi TAR-binding protein 0.0063 0.0139 0.0562
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0287 0.083 0.0983
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.0044 0.0044
Brugia malayi jmjC domain containing protein 0.0165 0.0455 0.1839
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0344 0.0926
Mycobacterium ulcerans DNA gyrase subunit B 0.0731 0.2195 0.2664
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0095 0.0239 0.0643
Schistosoma mansoni ferritin light chain 0.0025 0.0023 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0145 0.0145
Leishmania major hypothetical protein, conserved 0.0042 0.0076 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0179
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0038 0.0102
Trypanosoma cruzi diacylglycerol kinase, putative 0.0105 0.0269 0.0725
Echinococcus multilocularis ecdysone induced protein 78C 0.006 0.0132 0.0132
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0089 0.024
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0105 0.0269 0.1038
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0042 0.0076 0.0065
Brugia malayi mbt repeat family protein 0.0096 0.024 0.0969
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0053 0.0053
Echinococcus multilocularis ferritin 0.0025 0.0023 0.0023
Echinococcus granulosus transcription factor btf3 0.0069 0.0158 0.0158
Echinococcus granulosus carboxylesterase 5A 0.0082 0.0198 0.0198
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Trypanosoma brucei DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0026 0.0026 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Echinococcus multilocularis polycomb protein SCMH1 0.0096 0.024 0.024
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0059 0.0128 0.0128
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.006 0.0187
Plasmodium vivax diacylglycerol kinase, putative 0.0105 0.0269 0.1225
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0117 0.0435
Schistosoma mansoni phd/f-box containing protein 0.004 0.007 0.0069
Brugia malayi ecdysone receptor 0.0028 0.0034 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Loa Loa (eye worm) mbt repeat family protein 0.0096 0.024 0.0291
Echinococcus multilocularis caspase 2 0.0026 0.0026 0.0026
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0019 0.0006 0.0006
Brugia malayi Disco-interacting protein 2 homolog 0.0038 0.0062 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0034 0.0034
Trypanosoma brucei transcription factor BTF3, putative 0.0069 0.0158 0.0426
Schistosoma mansoni heat shock protein 0.0057 0.0122 0.0122
Trypanosoma brucei metacaspase 0.0026 0.0026 0.0069
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0458 0.1805
Schistosoma mansoni hypothetical protein 0.019 0.0531 0.0531
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0042 0.0076 0.0065
Trichomonas vaginalis heat shock protein, putative 0.0053 0.011 0.0393
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0098 0.0248 0.1667
Loa Loa (eye worm) hypothetical protein 0.0247 0.0707 0.0858
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0084
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0034 0.0258
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.007 0.0187
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0129 0.0344 0.0417
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0042 0.0076 0.0247
Echinococcus granulosus cpg binding protein 0.0277 0.0799 0.0799
Echinococcus granulosus caspase 8 0.0026 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0601 0.1795 0.2179
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0166 0.0458 0.5387
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0014 0.0055
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0117 0.042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0034 0.0034
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0014 0.0104
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0042 0.0076 0.0254
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Trypanosoma brucei DNA topoisomerase ii 0.0431 0.1272 0.3427
Schistosoma mansoni ran 0.0022 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0051 0.0103 0.0103
Schistosoma mansoni endoplasmin 0.0134 0.0357 0.0357
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Schistosoma mansoni survival motor neuron protein 0.0097 0.0243 0.0243
Echinococcus multilocularis isocitrate dehydrogenase 0.0047 0.0089 0.0089
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0319 0.0928 0.1126
Leishmania major importin beta-1 subunit, putative 0.0024 0.0021 0.0055
Trypanosoma brucei Heat shock protein 83, putative 0.0134 0.0357 0.0962
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0032 0.0046 0.0046
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0051 0.0103 0.036
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trypanosoma cruzi heat shock protein 90, putative 0.008 0.0193 0.0519
Echinococcus granulosus JmjC domain containing protein 4 0.004 0.007 0.007
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0034 0.0135
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.0044 0.0044
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0034 0.0041
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0123 0.0123
Plasmodium falciparum diacylglycerol kinase, putative 0.0105 0.0269 0.1225
Schistosoma mansoni lamin 0.0053 0.011 0.011
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0179
Trichomonas vaginalis hypothetical protein 0.0028 0.0032 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1597 0.4858 0.4858
Entamoeba histolytica hypothetical protein 0.0176 0.0489 0.0587
Echinococcus multilocularis dna polymerase eta 0.0107 0.0275 0.0275
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0034 0.0135
Loa Loa (eye worm) solute carrier family 6 member 4 0.0182 0.0508 0.0616
Toxoplasma gondii hypothetical protein 0.0031 0.0041 0.0317
Schistosoma mansoni transcription factor btf3 0.0069 0.0158 0.0158
Onchocerca volvulus 0.0028 0.0034 0.0138
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0082 0.0279
Schistosoma mansoni myst-related protein 0.0029 0.0035 0.0035
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0034 0.0033
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0105 0.0269 0.0269
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.004 0.007 0.0069
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0172 0.0475 0.1281
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0081 0.0196 0.0196
Schistosoma mansoni zinc finger protein 0.0032 0.0045 0.0045
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0057 0.0121 0.0435
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0221 0.0893
Loa Loa (eye worm) MH1 domain-containing protein 0.0032 0.0046 0.0056
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.019 0.0531 0.2146
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0105 0.0269 0.0269
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0042 0.0076 0.0665
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0172 0.0475 0.1281
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0129 0.0344 0.0926
Trypanosoma brucei diacylglycerol kinase, putative 0.0105 0.0269 0.0725
Plasmodium falciparum phd finger protein, putative 0.0028 0.0034 0.0152
Echinococcus granulosus sphingosine kinase 1 0.2696 0.824 0.824
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0059 0.0128 0.0128
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1224 0.3711 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0089 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-14 0.006 0.0132 0.0531
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0221 0.0221
Schistosoma mansoni sex comb on midleg homolog 0.0096 0.024 0.024
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0269 0.032
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0002 0.0002
Giardia lamblia Heat shock protein HSP 90-alpha 0.0134 0.0357 0.2033
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0139 0.0139
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0082 0.0332
Brugia malayi MH2 domain containing protein 0.0032 0.0046 0.0184
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0116
Schistosoma mansoni hypothetical protein 0.0097 0.0243 0.0243
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0089 0.0089
Schistosoma mansoni apoferritin-2 0.0025 0.0023 0.0022
Schistosoma mansoni jumonji/arid domain-containing protein 0.0165 0.0455 0.0455
Loa Loa (eye worm) CXXC zinc finger family protein 0.0262 0.0753 0.0914
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0196 0.0196
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0091 0.0227 0.0227
Brugia malayi MH1 domain containing protein 0.0032 0.0046 0.0184
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Mycobacterium leprae Probable two-component sensor kinase 0.0042 0.0076 0.0665
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0014 0.0036
Giardia lamblia Pms1-like protein 0.0042 0.0076 0.0432
Schistosoma mansoni cpg binding protein 0.0277 0.0799 0.0798
Entamoeba histolytica heat shock protein 90, putative 0.0134 0.0357 0.0427
Brugia malayi F/Y-rich N-terminus family protein 0.0083 0.0203 0.0819
Trichomonas vaginalis set domain proteins, putative 0.0478 0.1418 0.571
Echinococcus multilocularis zinc finger protein 0.0032 0.0045 0.0045
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0026 0.0197
Brugia malayi jmjC domain containing protein 0.004 0.007 0.028
Leishmania major mitochondrial DNA topoisomerase II 0.0431 0.1272 0.3427
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.011 0.0133
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Plasmodium falciparum endoplasmin, putative 0.0096 0.0241 0.1095
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0186 0.0519 0.3592
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.006 0.0132 0.0132
Trichomonas vaginalis heat shock protein, putative 0.0134 0.0357 0.1396
Loa Loa (eye worm) nuclear hormone receptor 0.0028 0.0034 0.0041
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0047 0.0089 0.0089
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0489 0.145 0.145
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0034 0.0034
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0081 0.0196 0.0196
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0176 0.0489 0.0489
Leishmania major sphingosine kinase A, B, putative 0.0105 0.0269 0.0725
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Leishmania major hypothetical protein, conserved 0.0025 0.0022 0.0059
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0117 0.0117
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0095 0.0239 0.0995
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0105 0.0269 0.0725
Echinococcus granulosus caspase 0.0026 0.0026 0.0026
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.0508 0.2051
Echinococcus granulosus zinc finger protein 0.0032 0.0045 0.0045
Echinococcus multilocularis nuclear receptor nhr 48 0.0028 0.0034 0.0034
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0458 0.1805
Onchocerca volvulus 0.0097 0.0243 0.1632
Loa Loa (eye worm) TOPoisomerase family member 0.0186 0.0519 0.063
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0357 0.0962
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0002 0.0008
Brugia malayi kinase, mitochondrial precursor 0.0042 0.0076 0.0307
Schistosoma mansoni nuclear receptor 0.0028 0.0034 0.0033
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0073 0.0171 0.0171
Echinococcus multilocularis peregrin 0.0031 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0838 0.2523 0.2523
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0021 0.0028
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0095 0.0239 0.0263
Plasmodium falciparum metacaspase-like protein 0.0026 0.0026 0.0117
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0209 0.059 0.059
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0196 0.0196
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.0166 0.0166
Mycobacterium tuberculosis Possible two component sensor kinase 0.0042 0.0076 0.0065
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0042 0.0076 0.0254
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0037 0.0284
Brugia malayi jmjC domain containing protein 0.004 0.007 0.028
Loa Loa (eye worm) endoplasmin 0.0134 0.0357 0.0434
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0579 0.1728 0.4656
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.019 0.0531 0.0531
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.005
Schistosoma mansoni alpha glucosidase 0.0037 0.006 0.0059
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0047 0.0089 0.0089
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Trypanosoma cruzi ISWI complex protein 0.0024 0.002 0.0054
Mycobacterium ulcerans two component sensor kinase MprB 0.0042 0.0076 0.0092
Echinococcus multilocularis microtubule associated protein 2 0.2778 0.8493 0.8493
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Brugia malayi hypothetical protein 0.0032 0.0044 0.0177
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.006 0.0132 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-31 0.006 0.0132 0.0531
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0031
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0245 0.0699 0.8376
Echinococcus multilocularis disco interacting protein 2 0.004 0.0068 0.0068
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0028 0.0034 0.0033
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.0002 0.0012
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0089 0.0108
Echinococcus multilocularis neuropeptide receptor A26 0.0943 0.2847 0.2847
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0458 0.1233
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0042 0.0076 0.0254
Plasmodium vivax endoplasmin, putative 0.0134 0.0357 0.1627
Echinococcus granulosus nuclear receptor nhr 48 0.0028 0.0034 0.0034
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0028 0.0034 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0089 0.0108
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0109 0.0281 0.0281
Loa Loa (eye worm) RecQ helicase 0.0044 0.0082 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.022 0.022
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0014 0.0077
Trypanosoma brucei unspecified product 0.0039 0.0067 0.0179
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0121 0.0487
Leishmania major mitochondrial DNA polymerase beta 0.1224 0.3711 1
Brugia malayi beta-NAC-like protein 0.0069 0.0158 0.0639
Echinococcus granulosus histone acetyltransferase MYST2 0.0109 0.0281 0.0281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Echinococcus granulosus phd:f box containing protein 0.004 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Brugia malayi Pre-SET motif family protein 0.0065 0.0145 0.0586
Loa Loa (eye worm) heat shock protein 75 0.0057 0.0122 0.0148
Loa Loa (eye worm) hypothetical protein 0.0109 0.0281 0.0341
Echinococcus multilocularis phosphoglycerate kinase 1 0.0166 0.0458 0.0458
Schistosoma mansoni hypothetical protein 0.3268 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0075
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Onchocerca volvulus 0.0096 0.0242 0.1624
Echinococcus multilocularis expressed protein 0.0025 0.0023 0.0023
Trypanosoma cruzi DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0021 0.0028
Echinococcus granulosus importin subunit beta 1 0.003 0.0038 0.0038
Plasmodium falciparum basic transcription factor 3b, putative 0.0069 0.0158 0.072
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0129 0.0344 0.0344
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0166 0.0458 0.3527
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.003
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Schistosoma mansoni apoferritin-2 0.0025 0.0023 0.0022
Echinococcus granulosus expressed protein 0.0025 0.0023 0.0023
Brugia malayi nuclear receptor NHR-88 0.0028 0.0034 0.0135
Brugia malayi DNA topoisomerase III 0.0051 0.0103 0.0413
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0166
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Loa Loa (eye worm) hypothetical protein 0.0055 0.0115 0.0139
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0042 0.0076 0.0065
Entamoeba histolytica Ran family GTPase 0.0022 0.0014 0.001
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0053 0.0239
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0026 0.0069
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0047 0.0089 0.024
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0117 0.0142
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0041 0.0041
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0269 0.032
Schistosoma mansoni zinc finger protein 0.0028 0.0034 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0145 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.0132 0.0531
Trichomonas vaginalis sphingosine kinase, putative 0.0105 0.0269 0.1038
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0166 0.0458 0.3527
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0198 0.0198
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0121 0.0146
Entamoeba histolytica hypothetical protein 0.0176 0.0489 0.0587
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.0132 0.0132
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0041 0.0041
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0042 0.0076 0.0065
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0269 0.032
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0042 0.0076 0.0162
Echinococcus multilocularis Diacylglycerol kinase theta 0.0105 0.0269 0.0269
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0068 0.0154 0.1187
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Brugia malayi MH1 domain containing protein 0.0018 0.0001 0.0004
Trypanosoma brucei DNA topoisomerase IA, putative 0.0051 0.0103 0.0275
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.006 0.0132 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Toxoplasma gondii hypothetical protein 0.0031 0.0041 0.0317
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0042 0.0076 0.0065
Trypanosoma brucei metacaspase MCA2 0.0026 0.0026 0.0069
Loa Loa (eye worm) hypothetical protein 0.0152 0.0413 0.0501
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0166 0.0458 0.2003
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.0269 0.0725
Onchocerca volvulus 0.0031 0.0041 0.0193
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0026 0.0069
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0106 0.0375
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.004 0.007 0.0534
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0002 0.0003
Echinococcus granulosus lamin 0.0053 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0089 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0269 0.1038
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0042 0.0076 0.0065
Loa Loa (eye worm) hypothetical protein 0.0135 0.0361 0.0438
Loa Loa (eye worm) hypothetical protein 0.0474 0.1404 0.1704
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0095 0.0239 0.2677
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0344 0.0926
Loa Loa (eye worm) hypothetical protein 0.0135 0.0362 0.044
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0014 0.0014
Loa Loa (eye worm) DR-78 0.0028 0.0034 0.0041
Echinococcus granulosus heat shock protein 90 0.0134 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Loa Loa (eye worm) hypothetical protein 0.0082 0.0198 0.024
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0019 0.0006 0.004
Brugia malayi Diacylglycerol kinase protein 2 0.0105 0.0269 0.1087
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0038 0.0173
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0018 0.008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.003
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0022 0.01
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0022 0.0169
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0021 0.0055
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Giardia lamblia DNA topoisomerase II 0.0144 0.0389 0.2212
Brugia malayi nuclear hormone receptor family member odr-7 0.0028 0.0034 0.0135
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0129 0.0344 0.0344
Trichomonas vaginalis sphingosine kinase, putative 0.0105 0.0269 0.1038
Entamoeba histolytica heat shock transcription factor, putative 0.0098 0.0248 0.0295
Trichomonas vaginalis DNA polymerase eta, putative 0.0057 0.0121 0.0435
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0269 0.0725
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0066 0.0299
Leishmania major C-8 sterol isomerase-like protein 0.0445 0.1314 0.3541
Echinococcus granulosus lamin dm0 0.0053 0.011 0.011
Treponema pallidum sodium- and chloride- dependent transporter 0.0182 0.0508 0.2233
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0082 0.0279
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Schistosoma mansoni hypothetical protein 0.0176 0.0489 0.0489
Schistosoma mansoni intermediate filament proteins 0.0053 0.011 0.011
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0146 0.0391
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0003
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0055 0.0116 0.0116
Trypanosoma cruzi DNA topoisomerase II, putative 0.0135 0.0362 0.0976
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0269 0.032
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.006 0.0132 0.0132
Loa Loa (eye worm) ICD-1 protein 0.0069 0.0158 0.0192
Loa Loa (eye worm) DNA topoisomerase III 0.0051 0.0103 0.0124
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0186 0.0519 0.3592
Loa Loa (eye worm) hypothetical protein 0.0105 0.0269 0.0327
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.006 0.016
Echinococcus granulosus DNA methyltransferase 2, putative 0.0019 0.0006 0.0006
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0038 0.0291
Brugia malayi nuclear hormone receptor family member nhr-6 0.0028 0.0034 0.0135
Plasmodium falciparum JmjC domain-containing protein, putative 0.004 0.007 0.0316
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0057 0.0122 0.0142
Echinococcus granulosus intermediate filament protein 0.0053 0.011 0.011
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0034 0.0041
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0042 0.0076 0.0092
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.006 0.0066
Trypanosoma brucei unspecified product 0.0039 0.0067 0.0179
Schistosoma mansoni cpg binding protein 0.0277 0.0799 0.0798
Brugia malayi glutaminase DH11.1 0.0821 0.2474 1
Schistosoma mansoni cpg binding protein 0.0262 0.0753 0.0752
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0421 0.1242 0.1507
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0458 0.0458
Leishmania major DNA polymerase eta, putative 0.0107 0.0275 0.0739
Brugia malayi PHD-finger family protein 0.0037 0.0061 0.0246
Loa Loa (eye worm) isocitrate dehydrogenase 0.0047 0.0089 0.0108
Brugia malayi hypothetical protein 0.0105 0.0269 0.1087
Echinococcus granulosus heat shock protein 90 0.0091 0.0227 0.0227
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Schistosoma mansoni ap endonuclease 0.0056 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Onchocerca volvulus 0.0049 0.0096 0.0578
Loa Loa (eye worm) ceramide kinase 0.0105 0.0269 0.0327
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0105 0.0269 0.2073
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0139 0.0169
Mycobacterium tuberculosis Conserved hypothetical protein 0.0645 0.1929 0.232
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0176 0.0489 0.0489
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0106 0.0375
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0179
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Loa Loa (eye worm) hypothetical protein 0.0227 0.0645 0.0783
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0579 0.1728 0.4656
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0096 0.024 0.1608
Brugia malayi Latrophilin receptor protein 2 0.019 0.0531 0.2146
Loa Loa (eye worm) jmjC domain-containing protein 0.0165 0.0455 0.0552
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0117 0.0115
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0057 0.0122 0.0122
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Plasmodium falciparum amino acid transporter, putative 0.0031 0.0041 0.0187
Leishmania major cathepsin L-like protease 0.0065 0.0146 0.0391
Trypanosoma brucei Sphingosine kinase 0.0105 0.0269 0.0725
Entamoeba histolytica heat shock transcription factor, putative 0.0098 0.0248 0.0295
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0068 0.0068
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0172 0.0475 0.1281
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0109 0.0281 0.1134
Schistosoma mansoni nuclear hormone receptor 0.006 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0445 0.1314 0.1595
Schistosoma mansoni retinoid-x-receptor (RXR) 0.006 0.0132 0.0131
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0105 0.0269 0.0327
Echinococcus granulosus microtubule associated protein 2 0.2778 0.8493 0.8493
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.006 0.024
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0089 0.0239
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0089 0.0081
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0431 0.1272 0.3427
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0117 0.0472
Giardia lamblia DNA topoisomerase III 0.0051 0.0103 0.0582
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0081 0.0196 0.0196
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0121 0.0325
Echinococcus granulosus tar DNA binding protein 0.0063 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Plasmodium vivax DNA gyrase subunit B, putative 0.0731 0.2195 1
Brugia malayi Bromodomain containing protein 0.0037 0.0061 0.0246
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0026 0.0197
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0042 0.0076 0.0092
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0445 0.1314 0.3541
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0051 0.0103 0.0124
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0042 0.0076 0.0076
Plasmodium vivax DNA topoisomerase 3, putative 0.0051 0.0103 0.0466
Loa Loa (eye worm) carboxylesterase 0.0082 0.0198 0.024
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0081 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0051 0.0103 0.0275
Brugia malayi SET domain containing protein 0.0026 0.0028 0.011
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0022 0.01
Loa Loa (eye worm) hypothetical protein 0.0082 0.0198 0.024
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.0458 0.1852
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0042 0.0076 0.0665
Echinococcus multilocularis Smad4 0.0032 0.0046 0.0046
Toxoplasma gondii heat shock protein 90, putative 0.0134 0.0357 0.2752
Plasmodium vivax heat shock protein 86, putative 0.0134 0.0357 0.1627
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Leishmania major DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Echinococcus multilocularis endoplasmin 0.0095 0.0239 0.0239
Schistosoma mansoni glutaminase 0.0821 0.2474 0.2473
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0042 0.0076 0.0585
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0034 0.0033
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0022 0.0059
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0014 0.0062
Brugia malayi Phosphoglycerate kinase 0.0061 0.0134 0.054
Onchocerca volvulus 0.0053 0.011 0.068
Echinococcus granulosus disco interacting protein 2 0.004 0.0068 0.0068
Brugia malayi nuclear receptor RXR 0.0028 0.0034 0.0135
Treponema pallidum phosphoglycerate kinase 0.0166 0.0458 0.2003
Echinococcus granulosus ceramide kinase 0.0105 0.0269 0.0269
Onchocerca volvulus 0.006 0.0132 0.0836
Echinococcus multilocularis FTZ F1 alpha 0.006 0.0132 0.0132
Echinococcus multilocularis heat shock protein 90 0.0134 0.0357 0.0357
Schistosoma mansoni sphingosine kinase A B 0.2696 0.824 0.824
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0047 0.0089 0.0405
Brugia malayi Ceramide kinase 0.0105 0.0269 0.1087
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0105 0.0269 0.1038
Loa Loa (eye worm) hypothetical protein 0.0096 0.024 0.0291
Trypanosoma brucei DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Mycobacterium ulcerans bacterioferritin BfrB 0.0025 0.0023 0.0027
Onchocerca volvulus 0.0053 0.011 0.068
Loa Loa (eye worm) hypothetical protein 0.0069 0.0159 0.0193
Trypanosoma cruzi heat shock protein, putative 0.0057 0.0122 0.0328
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0221 0.0221
Trichomonas vaginalis receptor histidine kinase, putative 0.0042 0.0076 0.0254
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0117 0.042
Trypanosoma cruzi metacaspase, putative 0.0026 0.0026 0.0069
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0014 0.0062
Echinococcus granulosus GPCR family 2 0.019 0.0531 0.0531
Toxoplasma gondii DNA topoisomerase family protein 0.0051 0.0103 0.0788
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0081 0.0196 0.0196
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0028 0.0034 0.0034
Mycobacterium ulcerans DNA topoisomerase I 0.0051 0.0103 0.0124
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.0054 0.0054
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.0034 0.0138
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0028 0.0034 0.0033
Onchocerca volvulus Alhambra homolog 0.0028 0.0034 0.0139
Echinococcus multilocularis ceramide kinase 0.0105 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0287 0.083 0.1007
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0022 0.01
Echinococcus granulosus caspase 2 0.0026 0.0026 0.0026
Trypanosoma brucei metacaspase 5, putative 0.0026 0.0026 0.0069
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.019 0.0531 0.0531
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.006 0.0132 0.0132
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0042 0.0076 0.0076
Mycobacterium ulcerans hypothetical protein 0.2696 0.824 1
Schistosoma mansoni transcription factor LCR-F1 0.0176 0.0489 0.0489
Onchocerca volvulus 0.0046 0.0089 0.0532
Trypanosoma cruzi DNA polymerase eta, putative 0.0068 0.0154 0.0415
Plasmodium falciparum zinc finger protein, putative 0.0029 0.0035 0.0159
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0166
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0579 0.1728 0.4656
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0047 0.0089 0.0089
Loa Loa (eye worm) nuclear factor I 0.0018 0.0001 0.0002
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Trypanosoma cruzi DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Echinococcus granulosus thyroid hormone receptor alpha 0.0028 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0089 0.0685
Giardia lamblia Grp94/Hsp90 0.0095 0.0239 0.1358
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0166
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0038 0.0102
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0103 0.0276
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Loa Loa (eye worm) apoptosis regulator protein 0.0081 0.0196 0.0238
Schistosoma mansoni RAR-like nuclear receptor 0.006 0.0132 0.0131
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0089 0.0239
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.007 0.0084
Echinococcus granulosus dna polymerase kappa 0.0057 0.0121 0.0121
Trypanosoma cruzi metacaspase, putative 0.0026 0.0026 0.0069
Mycobacterium ulcerans two component regulator - sensor kinase 0.0042 0.0076 0.0092
Echinococcus granulosus mothers against decapentaplegic 5 0.0032 0.0046 0.0046
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0035 0.0054 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.006 0.0132 0.016
Loa Loa (eye worm) hypothetical protein 0.004 0.0069 0.0083
Trypanosoma brucei heat shock protein 90, putative 0.0134 0.0357 0.0962
Schistosoma mansoni hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0601 0.1795 0.2179
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0008 0.001
Brugia malayi hypothetical protein 0.0032 0.0044 0.0177
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0445 0.1314 0.5313
Brugia malayi MH2 domain containing protein 0.0032 0.0046 0.0184
Schistosoma mansoni hypothetical protein 0.019 0.0531 0.0531
Echinococcus multilocularis serotonin transporter 0.0182 0.0508 0.0508
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0105 0.0269 0.0269
Brugia malayi jmjC domain containing protein 0.004 0.007 0.028
Echinococcus multilocularis dna polymerase kappa 0.0057 0.0121 0.0121
Schistosoma mansoni endoplasmin 0.0134 0.0357 0.0357
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0089 0.0108
Schistosoma mansoni hypothetical protein 0.0411 0.121 0.121
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0034 0.0258
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0034 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0089 0.0108
Echinococcus granulosus Diacylglycerol kinase zeta 0.0105 0.0269 0.0269
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0019 0.005
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0146 0.0391
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0105 0.0269 0.0269
Trypanosoma brucei Metacaspase-4 0.0026 0.0026 0.0069
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0096 0.024 0.024
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0057 0.0121 0.0121
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.002 0.0026
Schistosoma mansoni hypothetical protein 0.019 0.0531 0.0531
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0089 0.0822
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0054 0.0054
Schistosoma mansoni ferritin 0.0025 0.0023 0.0022
Schistosoma mansoni DNA helicase recq1 0.0018 0.0002 0.0002
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Trichomonas vaginalis heat shock protein, putative 0.0095 0.0239 0.0915
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Plasmodium vivax heat shock protein, putative 0.0199 0.0559 0.2545
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0146 0.0391
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.006 0.0132 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0158 0.0588
Brugia malayi Nuclear hormone receptor-like 1 0.006 0.0132 0.0531
Brugia malayi steroid hormone receptor 0.006 0.0132 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Onchocerca volvulus 0.0479 0.1419 1
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0186 0.0519 0.3592
Echinococcus multilocularis geminin 0.0838 0.2523 0.2523
Loa Loa (eye worm) intermediate filament protein 0.0053 0.011 0.0133
Schistosoma mansoni nuclear receptor nhr-48 0.0028 0.0034 0.0033
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0458 0.1233
Toxoplasma gondii exonuclease III APE 0.0056 0.0117 0.09
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0121 0.0146
Leishmania major DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0157 0.0157
Loa Loa (eye worm) MH2 domain-containing protein 0.0476 0.141 0.1712
Treponema pallidum DNA topoisomerase I (topA) 0.0051 0.0103 0.0368
Schistosoma mansoni thyroid hormone receptor 0.006 0.0132 0.0131
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0042 0.0076 0.0065
Mycobacterium tuberculosis Diacylglycerol kinase 0.0105 0.0269 0.03
Echinococcus multilocularis transcription factor Dp 1 0.0075 0.0176 0.0176
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.006 0.006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0034 0.0034
Brugia malayi Cell death protein 3 precursor 0.0026 0.0026 0.0103
Toxoplasma gondii DNA methyltransferase 2, putative 0.0019 0.0006 0.004
Echinococcus multilocularis lamin 0.0053 0.011 0.011
Entamoeba histolytica hypothetical protein, conserved 0.2696 0.824 1
Loa Loa (eye worm) transcription factor SMAD2 0.0476 0.141 0.1712
Echinococcus granulosus dna polymerase eta 0.0107 0.0275 0.0275
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0047 0.0089 0.024
Echinococcus multilocularis survival motor neuron protein 1 0.0474 0.1404 0.1404
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.006 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Loa Loa (eye worm) hypothetical protein 0.0247 0.0707 0.0858
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Leishmania major phosphoglycerate kinase C, glycosomal 0.0166 0.0458 0.1233
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0026 0.0197
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0089 0.0358
Brugia malayi nuclear hormone receptor 0.0028 0.0034 0.0135
Loa Loa (eye worm) hypothetical protein 0.0166 0.0458 0.0556
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0731 0.2195 0.2644
Brugia malayi RNA, U transporter 1 0.0085 0.0208 0.0838
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.006 0.016
Leishmania major GTP-binding protein, putative 0.0022 0.0014 0.0036
Loa Loa (eye worm) nuclear receptor NHR-67 0.0028 0.0034 0.0041
Loa Loa (eye worm) hypothetical protein 0.0411 0.121 0.1469
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0186 0.0519 0.2096
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0127 0.0154
Leishmania major diacylglycerol kinase, putative 0.0105 0.0269 0.0725
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0026 0.0117
Toxoplasma gondii hypothetical protein 0.0197 0.0553 0.4264
Schistosoma mansoni thyroid hormone receptor 0.006 0.0132 0.0131
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Toxoplasma gondii Hsp90 domain-containing protein 0.0199 0.0559 0.4306
Echinococcus multilocularis phd:f box containing protein 0.004 0.007 0.007
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0073 0.0171 0.0171
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0019 0.0016
Schistosoma mansoni DNA polymerase eta 0.0107 0.0275 0.0274
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0172 0.0475 0.1281
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0089 0.024
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.006 0.0132 0.0131
Plasmodium vivax JmjC domain containing protein 0.004 0.007 0.0316
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0458 0.1233
Giardia lamblia DNA topoisomerase III 0.0051 0.0103 0.0582
Plasmodium falciparum diacylglycerol kinase, putative 0.0105 0.0269 0.1225
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.006 0.0132 0.0132
Trypanosoma brucei DNA polymerase eta, putative 0.0107 0.0275 0.0739
Brugia malayi tailless protein 0.0028 0.0034 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-49 0.006 0.0132 0.0531
Trypanosoma cruzi Heat shock protein 83, putative 0.0134 0.0357 0.0962
Onchocerca volvulus Protein ultraspiracle homolog 0.006 0.0132 0.0836
Toxoplasma gondii hypothetical protein 0.0083 0.0201 0.1543
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0117 0.0665
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0042 0.0076 0.0092
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0243 0.0983
Echinococcus granulosus polycomb protein SCMH1 0.0096 0.024 0.024
Echinococcus granulosus snurportin 1 0.0319 0.0928 0.0928
Trichomonas vaginalis diacylglycerol kinase, putative 0.0105 0.0269 0.1038
Brugia malayi Hsp90 protein 0.0057 0.0122 0.0492
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0081 0.0196 0.0196
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Schistosoma mansoni lamin 0.0053 0.011 0.011
Leishmania major metacaspase, putative 0.0026 0.0026 0.0069
Echinococcus multilocularis lamin dm0 0.0053 0.011 0.011
Onchocerca volvulus 0.0182 0.0508 0.3512
Echinococcus multilocularis caspase 8 0.0026 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.0132 0.0132
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0014 0.0036
Brugia malayi Steroid receptor seven-up type 2 0.006 0.0132 0.0531
Giardia lamblia DINP protein human, muc B family 0.0057 0.0121 0.0686
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0129 0.0344 0.139
Brugia malayi MH2 domain containing protein 0.0476 0.141 0.5701
Mycobacterium ulcerans diacylglycerol kinase 0.0105 0.0269 0.0326
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0089 0.0822
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0027
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0089 0.024
Trypanosoma cruzi heat shock protein 90, putative 0.0091 0.0227 0.0611
Loa Loa (eye worm) latrophilin receptor protein 2 0.019 0.0531 0.0645
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0027
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0031 0.0041 0.0166
Trypanosoma cruzi heat shock protein 85, putative 0.0091 0.0227 0.0611
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0089 0.0101
Trichomonas vaginalis heat shock protein, putative 0.0095 0.0239 0.0915
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0117 0.0532
Echinococcus multilocularis GPCR, family 2 0.019 0.0531 0.0531
Brugia malayi MH1 domain containing protein 0.0018 0.0001 0.0004
Mycobacterium tuberculosis Conserved protein 0.2696 0.824 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trichomonas vaginalis helicase, putative 0.0052 0.0106 0.0375
Brugia malayi Phosphoglycerate kinase 0.0166 0.0458 0.185
Echinococcus granulosus TGF beta signal transducer SmadC 0.0032 0.0046 0.0046
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Schistosoma mansoni sodium/chloride dependent transporter 0.0182 0.0508 0.0507
Echinococcus multilocularis caspase 0.0026 0.0026 0.0026
Onchocerca volvulus 0.0065 0.0145 0.0932
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0041 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0388 0.1139 0.1139
Brugia malayi nuclear receptor RXR 0.0032 0.0044 0.0177
Schistosoma mansoni diacylglycerol kinase theta 0.0105 0.0269 0.0269
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0076 0.0346
Brugia malayi ImpB/MucB/SamB family protein 0.0107 0.0275 0.1109
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0089 0.0239
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0221 0.0221
Mycobacterium tuberculosis Probable two component sensor kinase 0.0042 0.0076 0.0065
Loa Loa (eye worm) steroid hormone receptor 0.006 0.0132 0.016
Schistosoma mansoni smad1 5 8 and 0.0032 0.0046 0.0046
Schistosoma mansoni terminal deoxycytidyl transferase 0.0057 0.0121 0.012
Schistosoma mansoni ferritin light chain 0.0025 0.0023 0.0022
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0601 0.1795 0.7256
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0117 0.0117
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0096 0.0095
Trichomonas vaginalis glutaminase, putative 0.0821 0.2474 1
Trypanosoma brucei ISWI complex protein 0.0024 0.002 0.0054
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Schistosoma mansoni heat shock protein 0.0134 0.0357 0.0357
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0221 0.0268
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.006 0.0187
Brugia malayi hypothetical protein 0.0247 0.0707 0.2857
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0182 0.0508 0.0507
Schistosoma mansoni hypothetical protein 0.0319 0.0928 0.0928
Echinococcus multilocularis mothers against decapentaplegic 5 0.0032 0.0046 0.0046
Leishmania major DNA topoisomerase 1A 0.0051 0.0103 0.0275
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0031 0.0041 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.006 0.0187
Brugia malayi nuclear hormone receptor 0.006 0.0132 0.0531
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.013
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0317
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0031 0.0041 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.006 0.016
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-40 0.006 0.0132 0.0531
Entamoeba histolytica DNA topoisomerase III, putative 0.0051 0.0103 0.0118
Trichomonas vaginalis bmru protein, putative 0.0105 0.0269 0.1038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.006 0.0132 0.016
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0042 0.0076 0.0065
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0145 0.1116
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0042 0.0076 0.0205
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Echinococcus granulosus mixed lineage leukemia protein mll 0.0059 0.0128 0.0128
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0128 0.0345
Echinococcus multilocularis smad 0.0032 0.0046 0.0046
Leishmania major hypothetical protein, conserved 0.0105 0.0269 0.0725
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.006 0.0132 0.0131
Schistosoma mansoni smad 0.0032 0.0046 0.0046
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0117 0.0142
Entamoeba histolytica hypothetical protein 0.0069 0.0158 0.0186
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0458 0.1233
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0025 0.0025
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0388 0.1139 0.1139
Brugia malayi photoreceptor-specific nuclear receptor 0.006 0.0132 0.0531
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.019 0.0531 0.0531
Loa Loa (eye worm) hypothetical protein 0.0105 0.0269 0.0327
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Brugia malayi Importin beta-1 subunit 0.003 0.0038 0.0153
Schistosoma mansoni alpha-glucosidase 0.0143 0.0387 0.0387
Brugia malayi ecdysteroid receptor 0.006 0.0132 0.0531
Echinococcus granulosus FTZ F1 alpha 0.006 0.0132 0.0132
Echinococcus granulosus neuropeptide s receptor 0.0943 0.2847 0.2847
Brugia malayi hypothetical protein 0.0028 0.0034 0.0135
Brugia malayi jmjC domain containing protein 0.004 0.007 0.028
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0055 0.0116 0.0116
Echinococcus granulosus serotonin transporter 0.0182 0.0508 0.0508
Plasmodium falciparum heat shock protein 90, putative 0.0199 0.0559 0.2545
Loa Loa (eye worm) hypothetical protein 0.0042 0.0076 0.0093
Echinococcus granulosus fetal alzheimer antigen falz 0.0035 0.0054 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.0132 0.0531
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0025 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0034 0.0034
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0089 0.0358
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0007
Brugia malayi intermediate filament protein 0.0053 0.011 0.0443
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0158 0.0588
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0032 0.0074
Echinococcus multilocularis rho GTPase activating protein 20 0.0051 0.0103 0.0103
Schistosoma mansoni alpha-glucosidase 0.0143 0.0387 0.0387
Brugia malayi diacylglycerol kinase 0.0105 0.0269 0.1087
Mycobacterium ulcerans heat shock protein 90 0.0095 0.0239 0.0289
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0034 0.0152
Brugia malayi latrophilin 2 splice variant baaae 0.0411 0.121 0.4891
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0042 0.0076 0.0092
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0042 0.0076 0.0092
Leishmania major DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.0458 0.0556
Echinococcus granulosus bloom syndrome protein 0.0044 0.0082 0.0082
Schistosoma mansoni apoptosis regulator bax 0.0081 0.0196 0.0196
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0186 0.0519 0.0519
Trypanosoma cruzi diacylglycerol kinase, putative 0.0105 0.0269 0.0725
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0042 0.0076 0.0205
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0117 0.0315
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.0132 0.0531
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0019 0.0006 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0044 0.0177
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Leishmania major phosphoglycerate kinase B, cytosolic 0.0166 0.0458 0.1233
Schistosoma mansoni Tr4/Tr2 (homologue) 0.006 0.0132 0.0131
Echinococcus granulosus phosphoglycerate kinase 1 0.0166 0.0458 0.0458
Plasmodium vivax phosphoglycerate kinase, putative 0.0166 0.0458 0.2084
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0014 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-1 0.006 0.0132 0.0531
Plasmodium vivax metacaspase 1, putative 0.0026 0.0026 0.0117
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0028 0.0034 0.0135
Echinococcus multilocularis dnaJ subfamily B 0.3268 1 1
Entamoeba histolytica hypothetical protein 0.0176 0.0489 0.0587
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.006 0.0132 0.016
Leishmania major DNA polymerase eta, putative 0.0068 0.0154 0.0415
Trichomonas vaginalis DNA topoisomerase II, putative 0.0186 0.0519 0.2053
Schistosoma mansoni myelin transcription factor 1 myt1 0.0109 0.0281 0.028
Loa Loa (eye worm) MBCTL1 0.0109 0.0281 0.0341
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0047 0.0089 0.0081
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0002 0.0016
Echinococcus multilocularis heat shock protein 90 0.0091 0.0227 0.0227
Trypanosoma brucei heat shock protein 90, putative 0.0134 0.0357 0.0962
Brugia malayi PHD-finger family protein 0.0024 0.0021 0.0083
Loa Loa (eye worm) hypothetical protein 0.0037 0.0061 0.0075
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0317
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0129 0.0344 0.0411
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Echinococcus granulosus acetylcholinesterase 0.0082 0.0198 0.0198
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.006 0.0132 0.016
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0134 0.036
Schistosoma mansoni jumonji/arid domain-containing protein 0.0165 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0109 0.0281 0.0281
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0105 0.0269 0.0725
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Schistosoma mansoni bromodomain containing protein 0.0075 0.0177 0.0176
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0121 0.0325
Toxoplasma gondii histone lysine demethylase JMJD6a 0.004 0.007 0.0534
Schistosoma mansoni smad1 5 8 and 0.0032 0.0046 0.0046
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0028 0.0034 0.0041
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0053 0.0037
Echinococcus granulosus endoplasmin 0.0095 0.0239 0.0239
Echinococcus multilocularis SAM and MBT domain containing protein 0.0096 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Brugia malayi Carboxylesterase family protein 0.0082 0.0198 0.0799
Schistosoma mansoni hypothetical protein 0.019 0.0531 0.0531
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0117 0.0315
Mycobacterium ulcerans putative regultory protein 0.0042 0.0076 0.0092
Schistosoma mansoni sphingoid long chain base kinase 0.2696 0.824 0.824
Plasmodium falciparum importin beta, putative 0.003 0.0038 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0002 0.0002
Toxoplasma gondii DNA topoisomerase 2, putative 0.0186 0.0519 0.3997
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0002 0.0016
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0357 0.0962
Brugia malayi isocitrate dehydrogenase 0.0047 0.0089 0.0359
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0041 0.0041
Brugia malayi DNA topoisomerase III beta-1 0.0051 0.0103 0.0413
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0105 0.0269 0.1038
Schistosoma mansoni phosphatidylserine receptor 0.004 0.007 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Loa Loa (eye worm) hypothetical protein 0.0046 0.0089 0.0108
Echinococcus granulosus jumonji domain containing 1A 0.004 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0057 0.0122 0.0122
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0317
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0019 0.005
Schistosoma mansoni smad1 5 8 and 0.0032 0.0046 0.0046
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0145 0.0145
Brugia malayi hypothetical protein 0.0028 0.0034 0.0135
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0176 0.0489 0.0587
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0221 0.0221
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Schistosoma mansoni Smad4 0.0032 0.0046 0.0046
Plasmodium falciparum phosphoglycerate kinase 0.0166 0.0458 0.2084
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0041 0.0041
Brugia malayi diacylglycerol kinase 0.0105 0.0269 0.1087
Brugia malayi Muscleblind-like protein 0.0152 0.0413 0.1668
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0035 0.0054 0.0054
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0089 0.0108
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0731 0.2195 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0057 0.0121 0.0147
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0053 0.0239
Giardia lamblia Heat shock protein HSP 90-alpha 0.0091 0.0227 0.1292
Trichomonas vaginalis bmru protein, putative 0.0105 0.0269 0.1038
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0139 0.0562
Loa Loa (eye worm) hypothetical protein 0.0046 0.0089 0.0108
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.006 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0105 0.0269 0.0327
Toxoplasma gondii heat shock protein 75, putative 0.0057 0.0122 0.0938
Trypanosoma brucei heat shock protein 84, putative 0.0057 0.0122 0.0328
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0209 0.059 0.059
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0026 0.0026 0.0103
Brugia malayi Endoplasmin precursor 0.0134 0.0357 0.1443
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0089 0.0108
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.006 0.0132 0.0132
Echinococcus granulosus smad 0.0032 0.0046 0.0046
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0042 0.0076 0.0247
Brugia malayi RNA binding protein 0.0063 0.0139 0.0562
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.007 0.0084
Schistosoma mansoni SET domain protein 0.0022 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0182 0.0508 0.0616
Brugia malayi GRF zinc finger family protein 0.0051 0.0103 0.0413
Toxoplasma gondii diacylglycerol kinase, putative 0.0105 0.0269 0.2073
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0146 0.0391
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0022 0.0059
Loa Loa (eye worm) glutaminase 0.0821 0.2474 0.3002
Leishmania major cathepsin L-like protease 0.0065 0.0146 0.0391
Brugia malayi orphan nuclear receptor NR2E1 0.0028 0.0034 0.0135
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0014 0.0036
Trichomonas vaginalis ferritin, putative 0.0025 0.0023 0.0035
Loa Loa (eye worm) hypothetical protein 0.2696 0.824 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0057 0.0121 0.014
Loa Loa (eye worm) diacylglycerol kinase 2 0.0105 0.0269 0.0327
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0083 0.0201 0.0912
Trypanosoma cruzi metacaspase, putative 0.0026 0.0026 0.0069
Onchocerca volvulus 0.0262 0.0753 0.5258
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Onchocerca volvulus Huntingtin homolog 0.0247 0.0707 0.4932
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0026 0.0026 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Leishmania major DNA topoisomerase ii 0.0135 0.0362 0.0976
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.004 0.007 0.0187
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0105 0.0269 0.2073
Brugia malayi hypothetical protein 0.0031 0.0041 0.0166
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0042 0.0076 0.0092
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0042 0.0076 0.0585
Leishmania major heat shock protein, putative 0.0057 0.0122 0.0328
Loa Loa (eye worm) hypothetical protein 0.003 0.0038 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Loa Loa (eye worm) hypothetical protein 0.0098 0.0248 0.0302
Echinococcus multilocularis tumor protein p63 0.0332 0.0967 0.0967
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0089 0.0089
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0057 0.0121 0.012
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0034 0.0034
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0158 0.0426
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.0458 0.0458
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0042 0.0076 0.0065
Loa Loa (eye worm) acetylcholinesterase 1 0.0082 0.0198 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Schistosoma mansoni caspase-3 (C14 family) 0.0026 0.0026 0.0026
Loa Loa (eye worm) glutaminase 2 0.0821 0.2474 0.3002
Brugia malayi CXXC zinc finger family protein 0.0262 0.0753 0.3042
Trichomonas vaginalis heat shock protein, putative 0.0091 0.0227 0.0867
Brugia malayi Carboxylesterase family protein 0.0082 0.0198 0.0799
Entamoeba histolytica heat shock transcription factor, putative 0.0098 0.0248 0.0295
Entamoeba histolytica DNA topoisomerase III, putative 0.0051 0.0103 0.0118
Schistosoma mansoni hypothetical protein 0.0592 0.1768 0.1767
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0019 0.0006 0.0024
Plasmodium falciparum heat shock protein 90, putative 0.0053 0.011 0.0502
Echinococcus multilocularis histone acetyltransferase MYST2 0.0109 0.0281 0.0281
Brugia malayi Calcitonin receptor-like protein seb-1 0.0601 0.1795 0.7256
Leishmania major modification methylase-like protein 0.0019 0.0006 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.0132 0.0531
Brugia malayi Pre-SET motif family protein 0.0421 0.1242 0.5018
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0041 0.0187
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0053 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Onchocerca volvulus 0.0051 0.0103 0.0628
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.006 0.0132 0.016
Echinococcus granulosus transcription factor Dp 1 0.0075 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0182 0.0508 0.0616
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0051 0.0103 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.0132 0.0531
Plasmodium vivax amine transporter, putative 0.0031 0.0041 0.0187
Schistosoma mansoni protein phosphatase 2C 0.004 0.007 0.0069
Mycobacterium ulcerans hypothetical protein 0.0046 0.0089 0.0108
Plasmodium vivax importin-beta 2, putative 0.003 0.0038 0.0172
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0059 0.0128 0.0128
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0089 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Trypanosoma cruzi metacaspase, putative 0.0026 0.0026 0.0069
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.006 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.008 0.0192 0.0232
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.004 0.0068 0.0067
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0042 0.0076 0.0247
Echinococcus granulosus ecdysone induced protein 78C 0.006 0.0132 0.0132
Echinococcus granulosus retinoic acid receptor rxr beta a 0.006 0.0132 0.0132
Echinococcus multilocularis transcription factor btf3 0.0069 0.0158 0.0158
Echinococcus multilocularis cpg binding protein 0.0277 0.0799 0.0799
Echinococcus granulosus survival motor neuron protein 1 0.0474 0.1404 0.1404
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.021 0.0591 0.1593
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0051 0.0103 0.0103
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0196 0.0196
Schistosoma mansoni importin beta-1 0.003 0.0038 0.0038
Echinococcus granulosus heat shock protein 0.0134 0.0357 0.0357
Trypanosoma brucei metacaspase MCA3 0.0026 0.0026 0.0069
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0344 0.0926
Loa Loa (eye worm) heat shock protein 90 0.0134 0.0357 0.0434
Plasmodium falciparum DNA topoisomerase 3, putative 0.0051 0.0103 0.0466
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0054 0.0053
Plasmodium vivax heat shock protein 90, putative 0.0057 0.0122 0.0555
Leishmania major hypothetical protein, conserved 0.0105 0.0269 0.0725
Onchocerca volvulus Huntingtin homolog 0.0247 0.0707 0.4932
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Loa Loa (eye worm) histone methyltransferase 0.0073 0.0171 0.0208
Onchocerca volvulus 0.0096 0.024 0.1608
Plasmodium falciparum DNA topoisomerase 2 0.0186 0.0519 0.2362
Entamoeba histolytica DNA topoisomerase II, putative 0.0186 0.0519 0.0623
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1224 0.3711 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.006 0.0187
Echinococcus multilocularis neuropeptide s receptor 0.0943 0.2847 0.2847
Mycobacterium ulcerans phosphoglycerate kinase 0.0166 0.0458 0.0555
Trichomonas vaginalis sensor histidine kinase, putative 0.0042 0.0076 0.0254
Trypanosoma brucei C-8 sterol isomerase, putative 0.0445 0.1314 0.3541
Mycobacterium ulcerans hypothetical protein 0.0645 0.1929 0.2341
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0042 0.0076 0.0254
Trichomonas vaginalis receptor histidine kinase, putative 0.0042 0.0076 0.0254
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0117 0.0532
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1224 0.3711 1
Schistosoma mansoni ferritin 0.0025 0.0023 0.0022
Leishmania major hypothetical protein, conserved 0.004 0.007 0.0187
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0198 0.0198
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0166 0.0458 0.053
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0026 0.0026 0.0026
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0041 0.0041
Echinococcus multilocularis snurportin 1 0.0319 0.0928 0.0928
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0051 0.0103 0.0102
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0105 0.0269 0.0269
Chlamydia trachomatis DNA gyrase subunit B 0.0731 0.2195 1
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0134 0.036
Trypanosoma cruzi DNA topoisomerase II, putative 0.0135 0.0362 0.0976
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.019 0.0531 0.0531
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Loa Loa (eye worm) hypothetical protein 0.0135 0.0362 0.044
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0051 0.0103 0.0275
Plasmodium falciparum heat shock protein 90 0.0134 0.0357 0.1627
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.003
Schistosoma mansoni jumonji domain containing protein 0.004 0.007 0.0069
Echinococcus multilocularis JmjC domain containing protein 4 0.004 0.007 0.007
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0042 0.0076 0.0254
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0082 0.0082
Loa Loa (eye worm) serotonin transporter b 0.0182 0.0508 0.0616
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0081 0.0196 0.0196
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Brugia malayi hypothetical protein 0.0474 0.1404 0.5675
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0057 0.0121 0.0325
Toxoplasma gondii NAC domain-containing protein 0.0069 0.0158 0.1218
Echinococcus multilocularis heat shock protein 0.0134 0.0357 0.0357
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0042 0.0076 0.0205
Onchocerca volvulus 0.0028 0.0034 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.002 0.0026
Onchocerca volvulus 0.0105 0.0269 0.1815
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0006 0.0024
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0051 0.0103 0.036
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0089 0.0685
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trypanosoma brucei developmentally regulated phosphoprotein 0.0042 0.0076 0.0205
Echinococcus granulosus ferritin 0.0025 0.0023 0.0023
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0019 0.0021
Onchocerca volvulus 0.0031 0.0041 0.0193
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0089 0.0108
Loa Loa (eye worm) hypothetical protein 0.019 0.0531 0.0645
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.006 0.0073
Giardia lamblia Fructose-bisphosphate aldolase 0.0588 0.1756 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0057 0.0121 0.012
Onchocerca volvulus 0.0038 0.0062 0.0339
Treponema pallidum fructose-bisphosphate aldolase 0.0588 0.1756 0.7981
Brugia malayi Nuclear hormone receptor family member nhr-3 0.006 0.0132 0.0531
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0047 0.0089 0.0405
Trypanosoma cruzi Sphingosine kinase 0.0105 0.0269 0.0725
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0019 0.005
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0105 0.0269 0.0725
Echinococcus granulosus jumonji domain containing protein 0.004 0.0068 0.0068
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0158 0.0426
Echinococcus multilocularis lysine specific demethylase 6a 0.004 0.007 0.007
Trichomonas vaginalis endoplasmin, putative 0.0096 0.0241 0.0922
Echinococcus granulosus Smad4 0.0032 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0081 0.0196 0.0238
Plasmodium vivax diacylglycerol kinase, putative 0.0105 0.0269 0.1225
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0287 0.083 1
Leishmania major cathepsin L-like protease 0.0065 0.0146 0.0391
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.006 0.0132 0.0836
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0002 0.0002
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.006 0.0458
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Brugia malayi MH1 domain containing protein 0.0032 0.0046 0.0184
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0041 0.0041
Echinococcus multilocularis carboxylesterase 5A 0.0082 0.0198 0.0198
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0357 0.0962
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0042 0.0076 0.0346
Echinococcus multilocularis sphingosine kinase 1 0.2696 0.824 0.824
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0158 0.0588
Chlamydia trachomatis DNA topoisomerase I 0.0051 0.0103 0.0284
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.011 0.0443
Trichomonas vaginalis diacylglycerol kinase, putative 0.0105 0.0269 0.1038
Schistosoma mansoni diacylglycerol kinase theta 0.0105 0.0269 0.0269
Echinococcus multilocularis muscleblind protein 0.0152 0.0413 0.0413
Schistosoma mansoni nuclear receptor 0.0028 0.0034 0.0033
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.007 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Brugia malayi HSF-type DNA-binding domain containing protein 0.0098 0.0248 0.1003
Loa Loa (eye worm) hypothetical protein 0.0107 0.0275 0.0333
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0019 0.0006 0.0005
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0057 0.0122 0.0767
Brugia malayi nuclear receptor NHR-88 0.006 0.0132 0.0531
Echinococcus multilocularis jumonji domain containing 1A 0.004 0.007 0.007
Mycobacterium tuberculosis Conserved protein 0.0042 0.0076 0.0065
Onchocerca volvulus Bile acid receptor homolog 0.006 0.0132 0.0836
Leishmania major basic transcription factor 3a, putative 0.0069 0.0158 0.0426
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.006 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0152 0.0413 0.0501
Leishmania major diacylglycerol kinase-like protein 0.0105 0.0269 0.0725
Brugia malayi Bromodomain containing protein 0.0086 0.0212 0.0855
Schistosoma mansoni myst-related protein 0.0029 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0084
Trypanosoma cruzi DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0002 0.0009
Schistosoma mansoni sex comb on midleg homolog 0.0096 0.024 0.024
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0129 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0024 0.0021 0.0025
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0034 0.0034
Plasmodium falciparum transporter, putative 0.0031 0.0041 0.0187
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0051 0.0103 0.0788
Echinococcus multilocularis lysine specific demethylase 5A 0.015 0.0409 0.0409
Brugia malayi hypothetical protein 0.0176 0.0489 0.1976
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0081 0.0196 0.0792
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0028 0.0034 0.0034
Brugia malayi nuclear receptor NHR-67 0.0028 0.0034 0.0135
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0139 0.0169
Trypanosoma cruzi DNA polymerase eta, putative 0.0107 0.0275 0.0739
Echinococcus granulosus SAM and MBT domain containing protein 0.0096 0.024 0.024
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0014 0.0014
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0057 0.0121 0.0121
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0588 0.1756 0.2126
Brugia malayi heat shock protein 90 0.0134 0.0357 0.1443
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.0044 0.0054
Trypanosoma cruzi Sphingosine kinase 0.0105 0.0269 0.0725
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.0166 0.0166
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0117 0.0315
Treponema pallidum heat shock protein 90 0.0095 0.0239 0.0995
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0002 0.0008
Schistosoma mansoni pyruvate dehydrogenase 0.0042 0.0076 0.0076
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0042 0.0076 0.0092
Chlamydia trachomatis DNA gyrase subunit B 0.0486 0.1442 0.6503

Activities

Activity type Activity value Assay description Source Reference
MIC80 (functional) = 4 ug ml-1 Antifungal activity against Cryptococcus neoformans after 72 hrs by broth microdilution method ChEMBL. 24051242

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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