Detailed information for compound 21327

Basic information

Technical information
  • TDR Targets ID: 21327
  • Name: 2-amino-N-[(2R)-1-[[(1S)-1-formamido-2-(1H-in dol-3-yl)ethyl]amino]-3-(1H-indol-3-yl)-1-oxo propan-2-yl]-2-methylpropanamide
  • MW: 474.555 | Formula: C26H30N6O3
  • H donors: 6 H acceptors: 3 LogP: 2.85 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=CN[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@H](NC(=O)C(N)(C)C)Cc1c[nH]c2c1cccc2
  • InChi: 1S/C26H30N6O3/c1-26(2,27)25(35)31-22(11-16-13-28-20-9-5-3-7-18(16)20)24(34)32-23(30-15-33)12-17-14-29-21-10-6-4-8-19(17)21/h3-10,13-15,22-23,28-29H,11-12,27H2,1-2H3,(H,30,33)(H,31,35)(H,32,34)/t22-,23+/m1/s1
  • InChiKey: UJVDJAPJQWZRFR-PKTZIBPZSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-amino-N-[(1R)-2-[[(1S)-1-formamido-2-(1H-indol-3-yl)ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-2-methyl-propanamide
  • 2-amino-N-[(1R)-2-[[(1S)-1-formamido-2-(1H-indol-3-yl)ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxoethyl]-2-methylpropanamide
  • 2-azanyl-N-[(2R)-1-[[(1S)-1-formamido-2-(1H-indol-3-yl)ethyl]amino]-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]-2-methyl-propanamide
  • 2-amino-N-[(1R)-2-[[(1S)-1-formamido-2-(1H-indol-3-yl)ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-keto-ethyl]-2-methyl-propionamide
  • 2-amino-N-[(2R)-1-[[(1S)-1-formamido-2-(1H-indol-3-yl)ethyl]amino]-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]-2-methyl-propanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Subfamily M14A unassigned peptidase homolog 0.0223 0.0073 0.0282
Echinococcus multilocularis Tubulin beta 2C chain 0.1201 0.0437 0.1155
Schistosoma mansoni alpha-l-fucosidase 0.6662 0.2472 0.7335
Loa Loa (eye worm) hypothetical protein 0.0138 0.0041 0.0041
Brugia malayi Beta-glucuronidase precursor 0.0487 0.0171 0.0171
Schistosoma mansoni peptidase 0.0038 0.0004 0.0012
Giardia lamblia Beta tubulin 0.1201 0.0437 1
Schistosoma mansoni tubulin subunit beta 0.1201 0.0437 0.1297
Schistosoma mansoni neuropeptide F-like receptor 0.1095 0.0398 0.118
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0006 0.0015
Trichomonas vaginalis trehalase, putative 0.0143 0.0043 0.0185
Brugia malayi Lectin C-type domain containing protein 0.0031 0.0001 0.0001
Echinococcus multilocularis bile acid beta glucosidase 0.1103 0.0401 0.1058
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.001 0.0107
Echinococcus multilocularis lysosomal alpha glucosidase 1.0191 0.3787 1
Loa Loa (eye worm) trehalase 0.0143 0.0043 0.0043
Echinococcus multilocularis beta galactosidase 0.0834 0.03 0.0793
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0036 0.0155
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0649 0.0231 0.0995
Trichomonas vaginalis alpha-L-fucosidase, putative 0.2923 0.1079 0.4639
Plasmodium vivax tubulin beta chain, putative 0.1201 0.0437 1
Trichomonas vaginalis beta-galactosidase, putative 0.098 0.0355 0.1526
Echinococcus granulosus Tolloid protein 1 0.0327 0.0111 0.0294
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.1095 0.0398 0.118
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Schistosoma mansoni beta-galactosidase 0.0834 0.03 0.0891
Toxoplasma gondii aspartyl protease ASP3 0.0093 0.0024 0.011
Onchocerca volvulus 0.0038 0.0004 0.0015
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0042 0.0005 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0014 0.004
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0227 0.0074 0.0804
Onchocerca volvulus 0.1095 0.0398 0.1544
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0157 0.0048 0.0221
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0152 0.0046 0.0199
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0227 0.0074 0.1686
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0042 0.0005 0.0056
Trichomonas vaginalis alpha-L-fucosidase, putative 0.2923 0.1079 0.4639
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0002 0.0009
Echinococcus granulosus lysosome membrane protein 2 0.0138 0.0041 0.0108
Mycobacterium tuberculosis Probable dehydrogenase 0.0127 0.0037 0.0168
Echinococcus multilocularis Zinc carboxypeptidase family protein 0.0038 0.0004 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0042 0.0005 0.0056
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0002 0.0006
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0127 0.0037 0.0168
Schistosoma mansoni hypothetical protein 0.1518 0.0555 0.1648
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Schistosoma mansoni glycogen phosphorylase 0.014 0.0042 0.0124
Brugia malayi Zinc carboxypeptidase family protein 0.0038 0.0004 0.0004
Brugia malayi Zinc carboxypeptidase family protein 0.0038 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Onchocerca volvulus 0.1095 0.0398 0.1544
Trypanosoma cruzi hypothetical protein, conserved 0.2507 0.0924 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Trichomonas vaginalis glycogen phosphorylase, putative 0.0323 0.011 0.0473
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1095 0.0398 0.118
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Echinococcus granulosus thioredoxin glutathione reductase 0.012 0.0035 0.0091
Brugia malayi Zinc metalloproteinase toh-2 precursor 0.0041 0.0005 0.0005
Onchocerca volvulus 0.1095 0.0398 0.1544
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0194 0.0062 0.0184
Loa Loa (eye worm) G-protein coupled receptor 0.1095 0.0398 0.0398
Brugia malayi Zinc carboxypeptidase family protein 0.0038 0.0004 0.0004
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0095 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0093 0.0024 0.0024
Brugia malayi hypothetical protein 0.005 0.0008 0.0008
Onchocerca volvulus Neuropeptide F receptor homolog 0.1095 0.0398 0.1544
Trypanosoma brucei Carboxypeptidase-like protein 0.0038 0.0004 0.0042
Trichomonas vaginalis alpha-mannosidase 2c1, putative 0.0087 0.0022 0.0095
Leishmania major beta tubulin 0.1201 0.0437 0.473
Echinococcus multilocularis tubulin subunit beta 0.1201 0.0437 0.1155
Brugia malayi Glycosyl hydrolases family 31 protein 0.1168 0.0425 0.0425
Trichomonas vaginalis alpha-mannosidase 2c1, putative 0.0146 0.0044 0.019
Schistosoma mansoni integrin alpha-ps 0.0069 0.0015 0.0045
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1095 0.0398 0.105
Echinococcus multilocularis mannosyl oligosaccharide 1,2 alpha mannosidase 0.0152 0.0046 0.0122
Plasmodium falciparum plasmepsin III 0.0093 0.0024 0.0543
Schistosoma mansoni hypothetical protein 0.0526 0.0186 0.0551
Schistosoma mansoni alpha-amylase 0.0084 0.0021 0.0062
Echinococcus multilocularis allatostatin A receptor 0.1095 0.0398 0.105
Plasmodium falciparum plasmepsin VIII, putative 0.0093 0.0024 0.0543
Leishmania major beta tubulin 0.1201 0.0437 0.473
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0002 0.0007
Echinococcus granulosus integrin alpha ps 0.0069 0.0015 0.004
Brugia malayi sulfakinin receptor protein 0.1095 0.0398 0.0398
Schistosoma mansoni bile acid beta-glucosidase-related 0.1103 0.0401 0.1188
Leishmania major beta tubulin 0.1201 0.0437 0.473
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.1095 0.0398 0.105
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.1095 0.0398 0.118
Echinococcus granulosus dnaJ subfamily B 0.0415 0.0144 0.0381
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0042 0.0005 0.0049
Schistosoma mansoni cpg binding protein 0.0031 0.0001 0.0003
Onchocerca volvulus 0.0042 0.0005 0.0021
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.014 0.0042 0.019
Mycobacterium leprae probable zinc metalloprotease 0.5817 0.2157 1
Schistosoma mansoni alpha-amylase 0.0084 0.0021 0.0062
Trichomonas vaginalis alpha-mannosidase, putative 0.0146 0.0044 0.019
Trypanosoma brucei beta tubulin 0.1201 0.0437 0.4734
Brugia malayi Serotonin receptor 0.1095 0.0398 0.0398
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0063 0.0013 0.0035
Onchocerca volvulus 0.0093 0.0024 0.0094
Schistosoma mansoni amine GPCR 0.1095 0.0398 0.118
Trichomonas vaginalis glucosylceramidase, putative 0.4334 0.1605 0.6901
Echinococcus granulosus tubulin subunit beta 0.1201 0.0437 0.1155
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1095 0.0398 0.118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0042 0.0005 0.0056
Echinococcus granulosus beta D xylosidase 2 0.007 0.0016 0.0042
Trichomonas vaginalis alpha-glucosidase, putative 0.2507 0.0924 0.3972
Onchocerca volvulus 0.1095 0.0398 0.1544
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Echinococcus multilocularis SWI:SNF matrix associated 0.0042 0.0005 0.0014
Brugia malayi Serotonin/octopamine receptor family protein 7 0.1095 0.0398 0.0398
Schistosoma mansoni mannosyl-oligosaccharide alpha-12-mannosidase 0.0152 0.0046 0.0137
Loa Loa (eye worm) hypothetical protein 0.0728 0.0261 0.0261
Brugia malayi aspartic protease BmAsp-1, identical 0.0093 0.0024 0.0024
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.1095 0.0398 0.105
Plasmodium falciparum plasmepsin V 0.0093 0.0024 0.0543
Brugia malayi phosphofructokinase 0.0125 0.0036 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0014 0.004
Onchocerca volvulus 0.0143 0.0043 0.0167
Brugia malayi Calcium binding EGF domain containing protein 0.0038 0.0004 0.0004
Echinococcus multilocularis somatostatin receptor 0.1095 0.0398 0.105
Loa Loa (eye worm) beta-glucuronidase 0.0487 0.0171 0.0171
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0017 0.0186
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Echinococcus granulosus glycogen phosphorylase 0.0323 0.011 0.029
Echinococcus granulosus Glycosyl transferase family 35 0.0323 0.011 0.029
Brugia malayi Pre-SET motif family protein 0.0233 0.0077 0.0077
Trichomonas vaginalis sucrase-isomaltase, putative 0.2286 0.0841 0.3619
Loa Loa (eye worm) zinc carboxypeptidase 0.0038 0.0004 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.1095 0.0398 0.105
Trypanosoma cruzi Carboxypeptidase-like protein 0.0038 0.0004 0.0042
Echinococcus multilocularis SWI:SNF matrix associated 0.0042 0.0005 0.0014
Onchocerca volvulus 0.1095 0.0398 0.1544
Schistosoma mansoni amine GPCR 0.1095 0.0398 0.118
Brugia malayi Trehalase family protein 0.005 0.0008 0.0008
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0029 0.0001 0.0001
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.5817 0.2157 0.2157
Schistosoma mansoni tubulin subunit beta 0.1201 0.0437 0.1297
Schistosoma mansoni CD36-like class B scavenger receptor 0.0138 0.0041 0.0122
Trichomonas vaginalis Periplasmic beta-glucosidase precursor, putative 0.007 0.0016 0.0068
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.001 0.0107
Echinococcus granulosus laminin 0.0105 0.0029 0.0076
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0227 0.0074 0.0319
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.2507 0.0924 0.0924
Onchocerca volvulus 0.1095 0.0398 0.1544
Brugia malayi Glycosyl hydrolases family 38 protein 0.0093 0.0024 0.0024
Echinococcus multilocularis neuropeptide Y receptor 0.1095 0.0398 0.105
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.001 0.01
Brugia malayi zinc metalloproteinase toh-2 precursor 0.0041 0.0005 0.0005
Echinococcus granulosus neuropeptide receptor 0.1095 0.0398 0.105
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0013 0.0039
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0014 0.0014
Trichomonas vaginalis alpha-mannosidase 2c1, putative 0.0081 0.002 0.0086
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0001 0.0007
Onchocerca volvulus Lysosome membrane protein 2 homolog 0.0138 0.0041 0.0159
Leishmania major zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 0.0038 0.0004 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0036 0.0155
Schistosoma mansoni tubulin subunit beta 0.1201 0.0437 0.1297
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0036 0.0003 0.0009
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0394 0.0136 0.036
Loa Loa (eye worm) phosphofructokinase 0.0125 0.0036 0.0036
Leishmania major beta tubulin 0.1201 0.0437 0.473
Loa Loa (eye worm) zinc carboxypeptidase 0.0038 0.0004 0.0004
Echinococcus granulosus peptide allatostatin:somatostatin 0.1095 0.0398 0.105
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0043 0.0185
Schistosoma mansoni survival motor neuron protein 0.0047 0.0007 0.0021
Brugia malayi Melatonin receptor type 1A 0.1095 0.0398 0.0398
Brugia malayi Alpha-L-fucosidase family protein 0.6662 0.2472 0.2472
Trichomonas vaginalis maltase-glucoamylase, putative 0.2507 0.0924 0.3972
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0876 0.0316 0.3416
Echinococcus granulosus rhodopsin orphan GPCR 0.1095 0.0398 0.105
Plasmodium falciparum plasmepsin I 0.0394 0.0136 0.3108
Schistosoma mansoni lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) 0.0059 0.0012 0.0035
Schistosoma mansoni neprilysin 0.1518 0.0555 0.1648
Trypanosoma cruzi lanosterol synthase, putative 0.0029 0.0001 0.0007
Brugia malayi gonadotropin-releasing hormone receptor 2 0.1095 0.0398 0.0398
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0036 0.0384
Toxoplasma gondii zinc carboxypeptidase, putative 0.0038 0.0004 0.0015
Plasmodium falciparum plasmepsin X 0.0093 0.0024 0.0543
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.1095 0.0398 0.118
Schistosoma mansoni family M14 non-peptidase homologue (M14 family) 0.0038 0.0004 0.0012
Onchocerca volvulus 0.0143 0.0043 0.0167
Trypanosoma cruzi metallo-peptidase, Clan MC, Family M14 0.0038 0.0004 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1095 0.0398 0.118
Leishmania major ATP-dependent phosphofructokinase 0.0125 0.0036 0.0384
Trichomonas vaginalis glycogen phosphorylase, putative 0.0323 0.011 0.0473
Schistosoma mansoni hypothetical protein 0.0047 0.0007 0.0021
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0663 0.0237 0.0237
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1095 0.0398 0.118
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0029 0.0001 0.0002
Giardia lamblia Rab geranylgeranyltransferase 0.0227 0.0074 0.1686
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0011 0.0011
Brugia malayi glutathione reductase 0.012 0.0035 0.0035
Leishmania major beta tubulin 0.1201 0.0437 0.473
Plasmodium falciparum tubulin beta chain 0.1201 0.0437 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0127 0.0037 0.0074
Schistosoma mansoni lamin 0.0056 0.0011 0.0031
Leishmania major beta tubulin 0.1201 0.0437 0.473
Loa Loa (eye worm) hypothetical protein 0.0876 0.0316 0.0316
Onchocerca volvulus 0.1095 0.0398 0.1544
Schistosoma mansoni hypothetical protein 0.1095 0.0398 0.118
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0042 0.0005 0.0015
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0042 0.0005 0.0049
Giardia lamblia 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase 0.0728 0.0261 0.5959
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Brugia malayi G protein-coupled receptor 0.1095 0.0398 0.0398
Echinococcus multilocularis Tubulin beta 2C chain 0.1201 0.0437 0.1155
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.2935 0.1083 0.3214
Chlamydia trachomatis SWIB complex protein 0.0042 0.0005 0.03
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0036 0.0155
Brugia malayi hypothetical protein 0.0143 0.0043 0.0043
Schistosoma mansoni histamine h1 receptor 0.1095 0.0398 0.118
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0002 0.0009
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0095 0.0025 0.0025
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0031 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.2507 0.0924 0.3972
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0042 0.0005 0.0014
Loa Loa (eye worm) TYRA-2 protein 0.1095 0.0398 0.0398
Echinococcus multilocularis neuropeptide receptor A26 0.1095 0.0398 0.105
Schistosoma mansoni lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) 0.0093 0.0024 0.0072
Echinococcus multilocularis neutral alpha glucosidase AB 0.2507 0.0924 0.2439
Echinococcus granulosus lamin dm0 0.0056 0.0011 0.0028
Brugia malayi beta-tubulin, identical 0.1201 0.0437 0.0437
Brugia malayi Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform 1 0.0152 0.0046 0.0046
Brugia malayi Trehalase family protein 0.0143 0.0043 0.0043
Echinococcus multilocularis neuropeptide s receptor 0.1095 0.0398 0.105
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.1095 0.0398 0.0398
Schistosoma mansoni hypothetical protein 0.1518 0.0555 0.1648
Echinococcus granulosus fmrfamide receptor 0.1095 0.0398 0.105
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.001 0.0042
Echinococcus granulosus intermediate filament protein 0.0056 0.0011 0.0028
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.1095 0.0398 0.0398
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.1095 0.0398 0.105
Loa Loa (eye worm) aspartyl protease 6 0.0093 0.0024 0.0024
Plasmodium vivax thioredoxin reductase, putative 0.012 0.0035 0.0776
Onchocerca volvulus Cytosolic carboxypeptidase 1 homolog 0.0038 0.0004 0.0015
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.1095 0.0398 0.0398
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0811 0.0292 0.0771
Loa Loa (eye worm) hypothetical protein 0.4299 0.1591 0.1591
Loa Loa (eye worm) peptidase family M13 containing protein 0.4299 0.1591 0.1591
Trichomonas vaginalis glucosylceramidase, putative 0.6268 0.2325 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.0026 0.0026
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.0075 0.0197
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Toxoplasma gondii NADPH-glutathione reductase 0.0042 0.0005 0.0021
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0029 0.0001 0.0003
Onchocerca volvulus 0.0034 0.0002 0.0009
Giardia lamblia Beta tubulin 0.1201 0.0437 1
Loa Loa (eye worm) ceramide glucosyltransferase 0.206 0.0757 0.0757
Loa Loa (eye worm) hypothetical protein 0.0138 0.0041 0.0041
Toxoplasma gondii zinc carboxypeptidase superfamily protein 0.0038 0.0004 0.0015
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.001 0.0026
Echinococcus multilocularis laminin 0.0105 0.0029 0.0076
Giardia lamblia Glycogen phosphorylase 0.0323 0.011 0.2503
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.1095 0.0398 0.118
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.001 0.0043
Schistosoma mansoni carboxypeptidase N (M14 family) 0.0038 0.0004 0.0012
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0001 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0042 0.0005 0.0056
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0029 0.0001 0.0001
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0029 0.0001 0.0003
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.1095 0.0398 0.118
Loa Loa (eye worm) hypothetical protein 0.0143 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0105 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.1518 0.0555 0.1648
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0001 0.0007
Brugia malayi ORL1-like opioid receptor 0.1095 0.0398 0.0398
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.1095 0.0398 0.105
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0514 0.0181 0.0181
Echinococcus granulosus lamin 0.0056 0.0011 0.0028
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0042 0.0005 0.0005
Loa Loa (eye worm) glutathione reductase 0.012 0.0035 0.0035
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.5817 0.2157 1
Toxoplasma gondii beta-1 tubulin, putative 0.1201 0.0437 0.2025
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.1168 0.0425 0.1826
Echinococcus granulosus Tubulin beta 2C chain 0.1201 0.0437 0.1155
Trichomonas vaginalis tubulin epsilon chain, putative 0.1201 0.0437 0.188
Onchocerca volvulus 0.0041 0.0005 0.0019
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.1417 0.0518 0.1536
Loa Loa (eye worm) hypothetical protein 0.0394 0.0136 0.0136
Plasmodium falciparum plasmepsin II 0.0394 0.0136 0.3108
Trichomonas vaginalis glutathione reductase, putative 0.0042 0.0005 0.0022
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0042 0.0005 0.0056
Echinococcus granulosus endoplasmic reticulum mannosyl oligosaccharide 0.0152 0.0046 0.0122
Entamoeba histolytica glycogen phosphorylase, putative 0.014 0.0042 0.0444
Loa Loa (eye worm) hypothetical protein 0.44 0.1629 0.1629
Brugia malayi Trehalase family protein 0.0143 0.0043 0.0043
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0017 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0002 0.0007
Brugia malayi neuropeptide F receptor 0.1095 0.0398 0.0398
Loa Loa (eye worm) neuropeptide F receptor 0.1095 0.0398 0.0398
Echinococcus granulosus glycogen debranching enzyme 0.0728 0.0261 0.0689
Schistosoma mansoni Nep2 peptidase (M13 family) 0.2935 0.1083 0.3214
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0011 0.0011
Treponema pallidum hypothetical protein 0.005 0.0008 0.176
Brugia malayi Fibulin-1 precursor 0.0105 0.0029 0.0029
Trypanosoma brucei beta tubulin 0.1201 0.0437 0.4734
Loa Loa (eye worm) zinc carboxypeptidase 0.0038 0.0004 0.0004
Echinococcus multilocularis fibrillin 1 0.0105 0.0029 0.0076
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0001 0.0003
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0157 0.0048 0.0128
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0042 0.0005 0.0056
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0194 0.0062 0.0664
Echinococcus multilocularis neuropeptide receptor 0.1095 0.0398 0.105
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0811 0.0292 0.0771
Loa Loa (eye worm) G-protein coupled receptor 0.1095 0.0398 0.0398
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0876 0.0316 0.0834
Brugia malayi TAR-binding protein 0.0064 0.0014 0.0014
Echinococcus multilocularis G protein coupled receptor 139 0.1095 0.0398 0.105
Leishmania major alpha glucosidase II subunit, putative 0.2507 0.0924 1
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0014 0.004
Echinococcus multilocularis neuropeptides capa receptor 0.1095 0.0398 0.105
Leishmania major beta tubulin 0.1201 0.0437 0.473
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.2935 0.1083 0.3214
Trichomonas vaginalis alpha-glucosidase, putative 0.2507 0.0924 0.3972
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1095 0.0398 0.118
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0029 0.0001 0.0002
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.1168 0.0425 0.1826
Trichomonas vaginalis glucosylceramidase, putative 0.6268 0.2325 1
Echinococcus multilocularis beta tubulin 0.1201 0.0437 0.1155
Echinococcus granulosus neuropeptides capa receptor 0.1095 0.0398 0.105
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0125 0.0036 0.0071
Entamoeba histolytica beta-galactosidase, putative 0.0662 0.0236 0.2554
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.44 0.1629 0.1629
Trichomonas vaginalis alpha-glucosidase, putative 0.2507 0.0924 0.3972
Echinococcus granulosus neuropeptide FF receptor 2 0.1095 0.0398 0.105
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0157 0.0048 0.0221
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0036 0.0003 0.0008
Schistosoma mansoni biogenic amine (5HT) receptor 0.1095 0.0398 0.118
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1095 0.0398 0.105
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0811 0.0292 0.0866
Trichomonas vaginalis glucosylceramidase, putative 0.6268 0.2325 1
Echinococcus granulosus Tubulin beta 2C chain 0.1201 0.0437 0.1155
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0663 0.0237 0.1017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1095 0.0398 0.118
Echinococcus granulosus CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Toxoplasma gondii beta tubulin 0.1201 0.0437 0.2025
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0227 0.0074 0.0074
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.1095 0.0398 0.118
Echinococcus multilocularis beta tubulin 0.1201 0.0437 0.1155
Echinococcus multilocularis rhodopsin orphan GPCR 0.1095 0.0398 0.105
Brugia malayi aspartic protease BmAsp-2, identical 0.0093 0.0024 0.0024
Echinococcus granulosus neuropeptide receptor A26 0.1095 0.0398 0.105
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0042 0.0005 0.0105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0024 0.0072
Schistosoma mansoni myosin xvIII 0.1095 0.0398 0.118
Trichomonas vaginalis glycoside hydrolases, putative 0.0569 0.0202 0.0867
Leishmania major beta tubulin 0.1201 0.0437 0.473
Loa Loa (eye worm) hypothetical protein 0.0314 0.0107 0.0107
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.2935 0.1083 0.3214
Echinococcus multilocularis CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Toxoplasma gondii calcium binding egf domain-containing protein 0.0105 0.0029 0.0131
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0811 0.0292 0.0866
Schistosoma mansoni tubulin subunit beta 0.1201 0.0437 0.1297
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0042 0.0005 0.0005
Schistosoma mansoni peptidase 0.0038 0.0004 0.0012
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0152 0.0046 0.0199
Echinococcus granulosus 7tm_1 domain containing protein 0.1095 0.0398 0.105
Onchocerca volvulus 0.1095 0.0398 0.1544
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0042 0.0005 0.0056
Brugia malayi Serotonin receptor 0.1095 0.0398 0.0398
Trypanosoma cruzi beta tubulin, putative 0.1201 0.0437 0.4734
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1095 0.0398 0.105
Schistosoma mansoni hypothetical protein 0.1518 0.0555 0.1648
Entamoeba histolytica glycogen debranching enzyme, putative 0.0728 0.0261 0.2819
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.1095 0.0398 0.118
Brugia malayi manba-prov protein 0.0318 0.0108 0.0108
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.1168 0.0425 0.1648
Trypanosoma brucei RNA helicase, putative 0.0103 0.0028 0.0304
Mycobacterium tuberculosis Probable reductase 0.0127 0.0037 0.0168
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0042 0.0005 0.0105
Schistosoma mansoni growth hormone secretagogue receptor 0.1095 0.0398 0.118
Schistosoma mansoni egf-like domain protein 0.0095 0.0025 0.0074
Echinococcus multilocularis Tubulin beta 2C chain 0.1201 0.0437 0.1155
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0227 0.0074 0.0074
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0014 0.004
Brugia malayi peptidase family M13 containing protein 0.1417 0.0518 0.0518
Echinococcus granulosus allatostatin A receptor 0.1095 0.0398 0.105
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0042 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0001 0.0001
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.6268 0.2325 0.2325
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0876 0.0316 0.0834
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0001 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1095 0.0398 0.118
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0811 0.0292 0.0866
Echinococcus multilocularis integrin alpha ps 0.0069 0.0015 0.004
Trichomonas vaginalis phosphofructokinase, putative 0.0125 0.0036 0.0155
Leishmania major beta tubulin 0.1201 0.0437 0.473
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0093 0.0024 0.0024
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0125 0.0036 0.0391
Echinococcus granulosus Tubulin beta 2C chain 0.1201 0.0437 0.1155
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0227 0.0074 0.0196
Loa Loa (eye worm) hypothetical protein 0.012 0.0035 0.0035
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0394 0.0136 0.036
Echinococcus granulosus neuropeptide Y receptor 0.1095 0.0398 0.105
Entamoeba histolytica hypothetical protein 0.007 0.0016 0.0164
Onchocerca volvulus 0.0038 0.0004 0.0015
Entamoeba histolytica oligo-1,6-glucosidase, putative 0.0084 0.0021 0.022
Schistosoma mansoni hypothetical protein 0.1095 0.0398 0.118
Schistosoma mansoni biogenic amine receptor 0.1095 0.0398 0.118
Loa Loa (eye worm) angiotensin-converting enzyme family protein 2.6865 1 1
Schistosoma mansoni hypothetical protein 0.007 0.0016 0.0047
Loa Loa (eye worm) hypothetical protein 0.0033 0.0002 0.0002
Schistosoma mansoni amine GPCR 0.3281 0.1212 0.3597
Echinococcus granulosus tubulin beta 4A class IVa 0.1201 0.0437 0.1155
Onchocerca volvulus 0.0056 0.0011 0.0041
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0002 0.0006
Entamoeba histolytica glycogenphosphorylase, putative 0.014 0.0042 0.0444
Echinococcus granulosus Tubulin beta 2C chain 0.1201 0.0437 0.1155
Onchocerca volvulus 0.0047 0.0007 0.0027
Plasmodium vivax aspartyl proteinase, putative 0.0394 0.0136 0.3108
Loa Loa (eye worm) tubulin beta chain 0.1201 0.0437 0.0437
Brugia malayi GnHR receptor homolog 0.2954 0.109 0.109
Echinococcus multilocularis alpha 1A adrenergic receptor 0.1095 0.0398 0.105
Brugia malayi Melibiase family protein 0.0663 0.0237 0.0237
Brugia malayi G-protein coupled receptor 0.1095 0.0398 0.0398
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.1417 0.0518 0.1536
Echinococcus granulosus neutral alpha glucosidase AB 0.2507 0.0924 0.2439
Plasmodium vivax hypothetical protein, conserved 0.0267 0.0089 0.2025
Echinococcus granulosus glycogen phosphorylase 0.0323 0.011 0.029
Entamoeba histolytica glycogen phosphorylase, putative 0.014 0.0042 0.0444
Leishmania major beta tubulin 0.1201 0.0437 0.473
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.001 0.0042
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0002 0.0017
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Echinococcus granulosus integrin alpha ps 0.0033 0.0002 0.0005
Chlamydia trachomatis DNA topoisomerase I 0.0042 0.0005 0.03
Schistosoma mansoni opsin-like receptor 0.1095 0.0398 0.118
Brugia malayi 6-phosphofructokinase 0.0125 0.0036 0.0036
Trypanosoma brucei glucosidase, putative 0.2507 0.0924 1
Echinococcus multilocularis SWI:SNF matrix associated 0.0042 0.0005 0.0014
Leishmania major beta tubulin 0.1201 0.0437 0.473
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0267 0.0089 0.0235
Echinococcus granulosus neuropeptide Y receptor 0.1095 0.0398 0.105
Schistosoma mansoni hypothetical protein 0.0936 0.0338 0.1004
Schistosoma mansoni hypothetical protein 0.1518 0.0555 0.1648
Onchocerca volvulus 0.0056 0.0011 0.0041
Loa Loa (eye worm) hypothetical protein 0.0131 0.0038 0.0038
Toxoplasma gondii hypothetical protein 0.0227 0.0074 0.0341
Trypanosoma brucei beta tubulin 0.1201 0.0437 0.4734
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0152 0.0046 0.0199
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0031 0.0001 0.0001
Leishmania major beta tubulin 0.1201 0.0437 0.473
Trichomonas vaginalis maltase-glucoamylase, putative 0.1168 0.0425 0.1826
Onchocerca volvulus 0.1095 0.0398 0.1544
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Trichomonas vaginalis mercuric reductase, putative 0.0042 0.0005 0.0022
Schistosoma mansoni beta-mannosidase 0.0318 0.0108 0.0321
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0002 0.0036
Brugia malayi Nematode astacin protease protein 30 0.0041 0.0005 0.0005
Echinococcus granulosus orexin receptor type 2 0.1095 0.0398 0.105
Schistosoma mansoni alpha-amylase 0.0084 0.0021 0.0062
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 1.0191 0.3787 0.3787
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0002 0.0036
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0042 0.0005 0.5
Echinococcus multilocularis thyroid hormone receptor alpha 0.0288 0.0097 0.0256
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0152 0.0046 0.0046
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0876 0.0316 0.0316
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0024 0.0072
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0394 0.0136 0.0136
Leishmania major beta tubulin 0.1201 0.0437 0.473
Echinococcus multilocularis cytosolic carboxypeptidase protein 5 0.0038 0.0004 0.001
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.1095 0.0398 0.105
Brugia malayi Amylo-alpha-1,6-glucosidase family protein 0.0728 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0095 0.0025 0.0025
Schistosoma mansoni integrin alpha-ps 0.0036 0.0003 0.0009
Plasmodium vivax aspartyl protease, putative 0.0093 0.0024 0.0543
Echinococcus granulosus CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Echinococcus granulosus 7TM GPCR rhodopsin 0.1095 0.0398 0.105
Echinococcus granulosus tm gpcr rhodopsin 0.1095 0.0398 0.105
Schistosoma mansoni cd36 antigen 0.0138 0.0041 0.0122
Mycobacterium ulcerans alpha-L-fucosidase 0.8286 0.3077 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.012 0.0035 0.0091
Loa Loa (eye worm) hypothetical protein 0.44 0.1629 0.1629
Onchocerca volvulus 0.0143 0.0043 0.0167
Loa Loa (eye worm) hypothetical protein 0.0029 0.0001 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0227 0.0074 0.0804
Echinococcus granulosus bile acid beta glucosidase 0.1103 0.0401 0.1058
Brugia malayi larval opioid receptor 0.1095 0.0398 0.0398
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0125 0.0036 0.0164
Echinococcus multilocularis serotonin receptor 0.1095 0.0398 0.105
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0006 0.0019
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0394 0.0136 0.0405
Echinococcus granulosus beta tubulin 0.1201 0.0437 0.1155
Echinococcus multilocularis 0.0038 0.0004 0.001
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0876 0.0316 0.7222
Echinococcus multilocularis rhodopsin orphan GPCR 0.1095 0.0398 0.105
Echinococcus granulosus tm gpcr rhodopsin 0.1095 0.0398 0.105
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Echinococcus multilocularis alpha mannosidase 2 0.0093 0.0024 0.0064
Mycobacterium ulcerans alpha-mannosidase 0.0146 0.0044 0.0127
Plasmodium falciparum plasmepsin VI 0.0394 0.0136 0.3108
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0042 0.0005 0.0014
Brugia malayi carbohydrate phosphorylase 0.0323 0.011 0.011
Trichomonas vaginalis tubulin beta chain, putative 0.1201 0.0437 0.188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1095 0.0398 0.118
Onchocerca volvulus 0.0223 0.0073 0.0282
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0194 0.0062 0.0163
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.4299 0.1591 0.1591
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.1095 0.0398 0.105
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.014 0.0042 0.0119
Schistosoma mansoni lamin 0.0056 0.0011 0.0031
Leishmania major beta tubulin 0.1201 0.0437 0.473
Loa Loa (eye worm) trehalase 0.0143 0.0043 0.0043
Echinococcus multilocularis glycogen phosphorylase 0.0323 0.011 0.029
Loa Loa (eye worm) alpha-L-fucosidase 0.6662 0.2472 0.2472
Schistosoma mansoni hypothetical protein 0.1095 0.0398 0.118
Trichomonas vaginalis glucosylceramidase, putative 0.4113 0.1522 0.6546
Loa Loa (eye worm) hypothetical protein 0.44 0.1629 0.1629
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0105 0.0029 0.0029
Brugia malayi Trehalase family protein 0.0143 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Mycobacterium tuberculosis Possible conserved exported protein 0.0881 0.0318 0.1472
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.2507 0.0924 0.3972
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0011 0.0047
Onchocerca volvulus 0.1095 0.0398 0.1544
Brugia malayi intermediate filament protein 0.0056 0.0011 0.0011
Loa Loa (eye worm) trehalase 0.005 0.0008 0.0008
Echinococcus granulosus fucosidase alpha L 1 tissue 0.8286 0.3077 0.8126
Loa Loa (eye worm) hypothetical protein 0.0033 0.0002 0.0002
Loa Loa (eye worm) DPY-31 protein 0.0041 0.0005 0.0005
Echinococcus granulosus biogenic amine 5HT receptor 0.1095 0.0398 0.105
Schistosoma mansoni ceramide glucosyltransferase 0.206 0.0757 0.2246
Loa Loa (eye worm) hypothetical protein 0.0228 0.0075 0.0075
Plasmodium vivax glutathione reductase, putative 0.012 0.0035 0.0776
Trichomonas vaginalis conserved hypothetical protein 0.0152 0.0046 0.0199
Schistosoma mansoni neuropeptide receptor 0.1095 0.0398 0.118
Echinococcus multilocularis g protein coupled receptor 0.1095 0.0398 0.105
Onchocerca volvulus 0.0143 0.0043 0.0167
Schistosoma mansoni CD36-like class B scavenger receptor 0.0138 0.0041 0.0122
Loa Loa (eye worm) hypothetical protein 0.005 0.0008 0.0008
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0011 0.0011
Schistosoma mansoni opsin-like receptor 0.1095 0.0398 0.118
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0002 0.0009
Trichomonas vaginalis tubulin gamma chain, putative 0.1201 0.0437 0.188
Trypanosoma cruzi lysosomal alpha-mannosidase precursor, putative 0.013 0.0038 0.0414
Echinococcus granulosus endothelin converting enzyme 1 0.5817 0.2157 0.5696
Schistosoma mansoni alpha-1 adrenergic receptor 0.1095 0.0398 0.118
Giardia lamblia Nuclear ATP/GTP-binding protein 0.0038 0.0004 0.0075
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0024 0.0072
Loa Loa (eye worm) hypothetical protein 0.0143 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0093 0.0024 0.0024
Schistosoma mansoni 6-phosphofructokinase 0.0125 0.0036 0.0107
Schistosoma mansoni biogenic amine receptor 0.1095 0.0398 0.118
Trypanosoma cruzi metallo-peptidase, Clan MC, Family M14, putative 0.0038 0.0004 0.0042
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.1518 0.0555 0.1648
Brugia malayi Pre-SET motif family protein 0.0034 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.5817 0.2157 0.2157
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0024 0.0072
Echinococcus multilocularis lysosomal alpha mannosidase 0.013 0.0038 0.0101
Loa Loa (eye worm) hypothetical protein 0.0056 0.0011 0.0011
Plasmodium vivax aspartyl protease, putative 0.0093 0.0024 0.0543
Brugia malayi trehalase I 0.005 0.0008 0.0008
Loa Loa (eye worm) BEN-1 protein 0.1201 0.0437 0.0437
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0152 0.0046 0.0046
Echinococcus granulosus Zinc carboxypeptidase family protein 0.0038 0.0004 0.001
Leishmania major zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 0.0038 0.0004 0.0036
Schistosoma mansoni neprilysin-2 (M13 family) 0.2935 0.1083 0.3214
Plasmodium vivax SET domain protein, putative 0.0034 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Trichomonas vaginalis glucosylceramidase, putative 0.6268 0.2325 1
Onchocerca volvulus 0.0223 0.0073 0.0282
Brugia malayi RE15519p 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0059 0.0012 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0042 0.0005 0.0056
Toxoplasma gondii hypothetical protein 0.0649 0.0231 0.107
Trichomonas vaginalis glucosylceramidase, putative 0.6268 0.2325 1
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.001 0.0042
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0002 0.0036
Echinococcus multilocularis lysosomal alpha glucosidase 1.0191 0.3787 1
Entamoeba histolytica tubulin family protein 0.1201 0.0437 0.473
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0042 0.0005 0.0105
Brugia malayi hypothetical protein 0.0093 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0002 0.0002
Trypanosoma cruzi zinc carboxypeptidase, putative 0.0038 0.0004 0.0042
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Trichomonas vaginalis tubulin epsilon chain, putative 0.1201 0.0437 0.188
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0095 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0103 0.0028 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.1095 0.0398 0.105
Loa Loa (eye worm) peptidase family M13 containing protein 0.4299 0.1591 0.1591
Loa Loa (eye worm) brahma associated protein 0.0042 0.0005 0.0005
Echinococcus multilocularis Tubulin beta 2C chain 0.1201 0.0437 0.1155
Schistosoma mansoni tubulin subunit beta 0.1201 0.0437 0.1297
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0002 0.0004
Schistosoma mansoni amine GPCR 0.1095 0.0398 0.118
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0194 0.0062 0.0184
Echinococcus granulosus CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.2507 0.0924 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Brugia malayi Trehalase protein 5 0.005 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Entamoeba histolytica glycogen phosphorylase, putative 0.0323 0.011 0.1184
Loa Loa (eye worm) 6-phosphofructokinase 0.0125 0.0036 0.0036
Schistosoma mansoni neuropeptide f receptor 76f 0.1095 0.0398 0.118
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.0005 0.0013
Trichomonas vaginalis alpha-glucosidase, putative 0.2507 0.0924 0.3972
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0152 0.0046 0.0199
Brugia malayi Trehalase family protein 0.0143 0.0043 0.0043
Echinococcus granulosus hypothetical protein 0.1095 0.0398 0.105
Echinococcus multilocularis CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Echinococcus granulosus cpg binding protein 0.0031 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) tubulin beta-2A chain 0.1201 0.0437 0.0437
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1095 0.0398 0.118
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0042 0.0005 0.0021
Toxoplasma gondii calcium binding egf domain-containing protein 0.0105 0.0029 0.0131
Brugia malayi Thioredoxin reductase 0.012 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0038 0.0004 0.0012
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0152 0.0046 0.0199
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Echinococcus granulosus rhodopsin orphan GPCR 0.1095 0.0398 0.105
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0029 0.0001 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.1095 0.0398 0.105
Echinococcus multilocularis neuropeptide Y receptor 0.1095 0.0398 0.105
Onchocerca volvulus 0.1095 0.0398 0.1544
Brugia malayi CXXC zinc finger family protein 0.0029 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0143 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0138 0.0041 0.0041
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0394 0.0136 0.0586
Loa Loa (eye worm) tubulin beta-4 chain 0.1201 0.0437 0.0437
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.2507 0.0924 0.428
Trichomonas vaginalis conserved hypothetical protein 0.0373 0.0129 0.0554
Trichomonas vaginalis tubulin alpha chain, putative 0.1201 0.0437 0.188
Treponema pallidum NADH oxidase 0.0042 0.0005 0.0886
Echinococcus granulosus tachykinin peptides receptor 99D 0.1095 0.0398 0.105
Trichomonas vaginalis glycogen debranching enzyme, putative 0.0728 0.0261 0.1122
Brugia malayi Integrin alpha pat-2 precursor 0.0153 0.0047 0.0047
Brugia malayi Tachykinin-like peptides receptor 99D 0.1095 0.0398 0.0398
Trypanosoma cruzi hypothetical protein, conserved 0.0227 0.0074 0.0804
Schistosoma mansoni amine GPCR 0.1095 0.0398 0.118
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Trichomonas vaginalis glucosylceramidase, putative 0.4113 0.1522 0.6546
Giardia lamblia NADH oxidase lateral transfer candidate 0.0042 0.0005 0.0105
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0084 0.0021 0.0021
Trypanosoma brucei metallo-peptidase, Clan MC, Family M14, putative 0.0038 0.0004 0.0042
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0002 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0014 0.004
Echinococcus granulosus alpha mannosidase 2 0.0028 0.0000030383 0.0000080225
Schistosoma mansoni hypothetical protein 0.0042 0.0005 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.1095 0.0398 0.105
Echinococcus multilocularis glycogen phosphorylase 0.0323 0.011 0.029
Brugia malayi trehalase 0.005 0.0008 0.0008
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0728 0.0261 0.1207
Schistosoma mansoni hypothetical protein 0.0762 0.0274 0.0811
Brugia malayi Glycosyl hydrolases family 31 protein 1.0191 0.3787 0.3787
Onchocerca volvulus 0.0093 0.0024 0.0094
Brugia malayi Glycosyl hydrolases family 31 protein 0.2507 0.0924 0.0924
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Brugia malayi SWIB/MDM2 domain containing protein 0.0042 0.0005 0.0005
Echinococcus granulosus subfamily M14A unassigned peptidase 0.0223 0.0073 0.0192
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0042 0.0005 0.011
Entamoeba histolytica tubulin family protein 0.1201 0.0437 0.473
Schistosoma mansoni lipoxygenase 0.0063 0.0013 0.0039
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0017 0.0186
Echinococcus multilocularis rhodopsin orphan GPCR 0.1095 0.0398 0.105
Leishmania major beta tubulin 0.1201 0.0437 0.473
Brugia malayi AKH receptor 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Brugia malayi hypothetical protein 0.0228 0.0075 0.0075
Echinococcus multilocularis sex peptide receptor 0.1095 0.0398 0.105
Onchocerca volvulus 0.0093 0.0024 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.001 0.0029
Onchocerca volvulus Ceramide glucosyltransferase homolog 0.206 0.0757 0.2939
Loa Loa (eye worm) hypothetical protein 0.0085 0.0021 0.0021
Loa Loa (eye worm) AStacin protease 0.0204 0.0066 0.0066
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0127 0.0037 0.0168
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Onchocerca volvulus Glycogen phosphorylase homolog 0.0323 0.011 0.0427
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.1417 0.0518 0.1536
Trypanosoma brucei lysosomal alpha-mannosidase precursor, putative 0.0103 0.0028 0.0302
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0876 0.0316 0.0938
Echinococcus multilocularis neuropeptides capa receptor 0.1095 0.0398 0.105
Echinococcus multilocularis CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.1095 0.0398 0.105
Onchocerca volvulus 0.0223 0.0073 0.0282
Loa Loa (eye worm) tubulin beta-1 chain 0.1201 0.0437 0.0437
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0042 0.0005 0.0014
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0042 0.0005 0.0279
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0327 0.0111 0.0331
Brugia malayi putative neuropeptide receptor 0.1095 0.0398 0.0398
Trypanosoma brucei trypanothione reductase 0.012 0.0035 0.0374
Echinococcus granulosus expressed protein 0.0417 0.0145 0.0383
Brugia malayi Glycosyl hydrolases family 38 protein 0.0093 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.005 0.0008 0.0008
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0152 0.0046 0.0199
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0004 0.0075
Schistosoma mansoni thyroid hormone receptor 0.0288 0.0097 0.0288
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0001 0.0007
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.1095 0.0398 0.105
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0029 0.0001 0.0003
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0036 0.0384
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0005 0.011
Schistosoma mansoni 6-phosphofructokinase 0.0125 0.0036 0.0107
Schistosoma mansoni alpha glucosidase 0.2507 0.0924 0.2741
Echinococcus multilocularis cpg binding protein 0.0031 0.0001 0.0003
Echinococcus multilocularis musashi 0.0056 0.0011 0.0028
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0194 0.0062 0.0062
Echinococcus multilocularis g protein coupled receptor 0.1095 0.0398 0.105
Brugia malayi Tubulin beta-1 chain 0.1201 0.0437 0.0437
Brugia malayi Carboxypeptidase A2 precursor 0.0038 0.0004 0.0004
Brugia malayi Zinc carboxypeptidase family protein 0.0038 0.0004 0.0004
Schistosoma mansoni tubulin subunit beta 0.1201 0.0437 0.1297
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.1095 0.0398 0.0398
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0267 0.0089 0.2025
Trypanosoma brucei beta tubulin 0.1201 0.0437 0.4734
Trichomonas vaginalis glucosylceramidase, putative 0.6268 0.2325 1
Trypanosoma cruzi lysosomal alpha-mannosidase precursor, putative 0.013 0.0038 0.0414
Loa Loa (eye worm) trehalase 0.0143 0.0043 0.0043
Schistosoma mansoni metallocarboxypeptidase D peptidase unit 2 (M14 family) 0.0038 0.0004 0.0012
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0233 0.0077 0.0077
Mycobacterium ulcerans zinc metalloprotease 0.5817 0.2157 0.7005
Loa Loa (eye worm) neuropeptide F receptor 0.1095 0.0398 0.0398
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0116 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0267 0.0089 0.0264
Leishmania major zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 0.0038 0.0004 0.0036
Schistosoma mansoni glycogen phosphorylase 0.0323 0.011 0.0326
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.1095 0.0398 0.105
Loa Loa (eye worm) hypothetical protein 0.0138 0.0041 0.0041
Schistosoma mansoni cathepsin D (A01 family) 0.1161 0.0422 0.1253
Trypanosoma cruzi metallo-peptidase, Clan MC, Family M14, putative 0.0038 0.0004 0.0042
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1095 0.0398 0.105
Trypanosoma brucei lysosomal alpha-mannosidase precursor, putative 0.013 0.0038 0.0414
Loa Loa (eye worm) hypothetical protein 0.0834 0.03 0.03
Echinococcus multilocularis tubulin beta 1 chain 0.1201 0.0437 0.1155
Toxoplasma gondii zinc carboxypeptidase superfamily protein 0.0038 0.0004 0.0015
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.1168 0.0425 0.4598
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0042 0.0005 0.0056
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.1095 0.0398 0.118
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0002 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0002 0.0007
Echinococcus multilocularis expressed protein 0.0417 0.0145 0.0383
Loa Loa (eye worm) hypothetical protein 0.0093 0.0024 0.0024
Leishmania major trypanothione reductase 0.012 0.0035 0.0367
Brugia malayi Dopamine receptor 0.1095 0.0398 0.0398
Onchocerca volvulus 0.1095 0.0398 0.1544
Trypanosoma cruzi hypothetical protein, conserved 0.0227 0.0074 0.0804
Echinococcus multilocularis endothelin converting enzyme 1 0.5817 0.2157 0.5696
Loa Loa (eye worm) glycosyl hydrolase family 38 protein 0.0146 0.0044 0.0044
Echinococcus multilocularis CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Echinococcus granulosus rhodopsin orphan GPCR 0.1095 0.0398 0.105
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0042 0.0005 0.0056
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0017 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.001 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.1095 0.0398 0.105
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Onchocerca volvulus Putative cubilin 0.0038 0.0004 0.0015
Loa Loa (eye worm) glycogen phosphorylase 0.0323 0.011 0.011
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0811 0.0292 0.0866
Trichomonas vaginalis glucosylceramidase, putative 0.4113 0.1522 0.6546
Plasmodium vivax plasmepsin V, putative 0.0093 0.0024 0.0543
Toxoplasma gondii aspartyl protease ASP1 0.0394 0.0136 0.0629
Schistosoma mansoni lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) 0.013 0.0038 0.0113
Loa Loa (eye worm) hypothetical protein 0.0033 0.0002 0.0002
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.1095 0.0398 0.105
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Trypanosoma cruzi protein farnesyltransferase, putative 0.0029 0.0001 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.1095 0.0398 0.105
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0001 0.0003
Echinococcus multilocularis G-protein coupled receptor, putative 0.1095 0.0398 0.105
Schistosoma mansoni intermediate filament proteins 0.0056 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0138 0.0041 0.0041
Schistosoma mansoni alpha-glucosidase 0.9073 0.337 1
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.1417 0.0518 0.1536
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0002 0.0007
Echinococcus granulosus alpha 1A adrenergic receptor 0.1095 0.0398 0.105
Loa Loa (eye worm) hypothetical protein 0.1148 0.0417 0.0417
Brugia malayi hypothetical protein 0.005 0.0008 0.0008
Echinococcus multilocularis Glycosyl transferase, family 35 0.0323 0.011 0.029
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0227 0.0074 0.0196
Echinococcus granulosus Tubulin beta 2C chain 0.1201 0.0437 0.1155
Brugia malayi Calcium binding EGF domain containing protein 0.0105 0.0029 0.0029
Echinococcus multilocularis Tubulin beta 2C chain 0.1201 0.0437 0.1155
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0031 0.0001 0.0001
Echinococcus granulosus sex peptide receptor 0.1095 0.0398 0.105
Loa Loa (eye worm) alpha amylase 0.0084 0.0021 0.0021
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Plasmodium falciparum plasmepsin VII 0.0093 0.0024 0.0543
Brugia malayi Pepsin A precursor 0.0093 0.0024 0.0024
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0014 0.0036
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0024 0.0072
Loa Loa (eye worm) trehalase 0.005 0.0008 0.0008
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0227 0.0074 0.0798
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0876 0.0316 0.7222
Mycobacterium tuberculosis Possible exported protein 0.0552 0.0195 0.0903
Loa Loa (eye worm) zinc metallopeptidase 4 0.1417 0.0518 0.0518
Plasmodium falciparum glutathione reductase 0.0042 0.0005 0.0105
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0227 0.0074 0.0804
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0029 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.005 0.0008 0.0008
Brugia malayi lysosomal alpha-mannosidase 0.0093 0.0024 0.0024
Plasmodium falciparum thioredoxin reductase 0.0042 0.0005 0.0105
Echinococcus multilocularis transfer RNA-Trp 0.0152 0.0046 0.0122
Echinococcus granulosus neuropeptide s receptor 0.1095 0.0398 0.105
Giardia lamblia Rab geranylgeranyltransferase 0.0876 0.0316 0.7222
Mycobacterium ulcerans beta-glucosidase BglS 0.007 0.0016 0.0034
Entamoeba histolytica phosphofructokinase, putative 0.0125 0.0036 0.0384
Plasmodium vivax plasmepsin IV, putative 0.0394 0.0136 0.3108
Plasmodium falciparum plasmepsin IX 0.0093 0.0024 0.0543
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0029 0.0001 0.0003
Onchocerca volvulus 0.0227 0.0074 0.0288
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.012 0.0035 0.0157
Loa Loa (eye worm) zinc metalloproteinase toh-2 0.0041 0.0005 0.0005
Trypanosoma brucei metallo-peptidase, Clan MC, Family M14, putative 0.0038 0.0004 0.0042
Brugia malayi 6-phosphofructokinase 0.0125 0.0036 0.0036
Echinococcus multilocularis beta D xylosidase 2 0.007 0.0016 0.0042
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0184 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Onchocerca volvulus 0.0029 0.0001 0.0002
Brugia malayi Zinc carboxypeptidase family protein 0.0038 0.0004 0.0004
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0017 0.0186
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0125 0.0036 1
Loa Loa (eye worm) mannosidase 0.0152 0.0046 0.0046
Giardia lamblia Ceramide glucosyltransferase 0.0934 0.0338 0.7716
Onchocerca volvulus Carboxypeptidase D homolog 0.0038 0.0004 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.1095 0.0398 0.118
Brugia malayi Ceramide glucosyltransferase 0.206 0.0757 0.0757
Trypanosoma brucei glycosyl hydrolase-like protein 0.1168 0.0425 0.4598
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0017 0.0051
Brugia malayi follicle stimulating hormone receptor 0.1095 0.0398 0.0398
Onchocerca volvulus 0.6942 0.2576 1
Toxoplasma gondii Alpha-galactosidase 0.0063 0.0013 0.0058
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0152 0.0046 0.0199
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0024 0.0072
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0227 0.0074 0.1686
Loa Loa (eye worm) TRE-2 protein 0.0143 0.0043 0.0043
Onchocerca volvulus Arrow homolog 0.0095 0.0025 0.0097
Toxoplasma gondii flagellar/basal body protein 0.0038 0.0004 0.0015
Echinococcus multilocularis non lysosomal glucosylceramidase 0.1103 0.0401 0.1058
Schistosoma mansoni thyroid hormone receptor 0.0288 0.0097 0.0288
Echinococcus multilocularis subfamily M14A unassigned peptidase 0.0223 0.0073 0.0192
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0002 0.0036
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0327 0.0111 0.0111
Schistosoma mansoni biogenic amine receptor 0.1095 0.0398 0.118
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0042 0.0005 0.0056
Loa Loa (eye worm) hypothetical protein 0.44 0.1629 0.1629
Mycobacterium ulcerans trehalose synthase TreS 0.0084 0.0021 0.0051
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.1095 0.0398 0.105
Echinococcus granulosus lysosomal alpha mannosidase 0.013 0.0038 0.0101
Trichomonas vaginalis alpha-glucosidase, putative 0.1168 0.0425 0.1826
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0152 0.0046 0.0199
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0125 0.0036 0.0391
Echinococcus granulosus neuropeptide receptor 0.1095 0.0398 0.105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0024 0.0072
Schistosoma mansoni alpha-amylase 0.0084 0.0021 0.0062
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0029 0.0001 0.0002
Mycobacterium tuberculosis Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (maltase-glucoamylase) (lysosomal alpha-glucosidas 0.0084 0.0021 0.0094
Brugia malayi Peptidase family M13 containing protein 0.5817 0.2157 0.2157
Toxoplasma gondii melibiase subfamily protein 0.0811 0.0292 0.1351
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0002 0.0009
Plasmodium falciparum thioredoxin reductase 0.012 0.0035 0.0776
Echinococcus granulosus rhodopsin orphan GPCR 0.1095 0.0398 0.105
Echinococcus granulosus alpha glucosidase 0.0084 0.0021 0.0055
Schistosoma mansoni protease m14 carboxypeptidase 0.0038 0.0004 0.0012
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0036 0.0003 0.0003
Brugia malayi astacin protease protein 30 0.0041 0.0005 0.0005
Schistosoma mansoni alpha-amylase 0.0084 0.0021 0.0062
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Schistosoma mansoni cathepsin D (A01 family) 0.1161 0.0422 0.1253
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0042 0.0005 0.0014
Echinococcus multilocularis neuropeptide FF receptor 2 0.1095 0.0398 0.105
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0001 0.0001
Brugia malayi brahma associated protein 60 kDa 0.0042 0.0005 0.0005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0663 0.0237 0.0702
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.2286 0.0841 0.9109
Echinococcus granulosus dro:myosuppressin receptor 0.1095 0.0398 0.105
Echinococcus multilocularis tachykinin peptides receptor 99D 0.1095 0.0398 0.105
Trypanosoma cruzi trypanothione reductase, putative 0.0042 0.0005 0.0056
Schistosoma mansoni hypothetical protein 0.1518 0.0555 0.1648
Schistosoma mansoni endothelin-converting enzyme-related 0.1417 0.0518 0.1536
Echinococcus granulosus 6 phosphofructokinase 0.0125 0.0036 0.0095
Trichomonas vaginalis glycoside hydrolase, putative 0.1397 0.051 0.2195
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.001 0.0026
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0017 0.0179
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1095 0.0398 0.0398
Schistosoma mansoni neuropeptide F-like receptor 0.1095 0.0398 0.118
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0116 0.0033 0.0033
Brugia malayi Dopamine receptor protein 1 0.1095 0.0398 0.0398
Schistosoma mansoni mannosidase alpha class 2a 0.0093 0.0024 0.0072
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1201 0.0437 0.1155
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0042 0.0005 0.0049
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0267 0.0089 0.0235
Toxoplasma gondii thioredoxin reductase 0.012 0.0035 0.0157
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0152 0.0046 0.0199
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.0075 0.0197
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0127 0.0037 0.0168
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.001 0.0026
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.1095 0.0398 0.1544
Loa Loa (eye worm) hypothetical protein 0.2882 0.1063 0.1063
Brugia malayi putative neuropeptide receptor NPR1 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0055 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.4299 0.1591 0.1591
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0017 0.0045
Loa Loa (eye worm) hypothetical protein 0.0034 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0029 0.0001 0.0002
Echinococcus granulosus tubulin beta 1 chain 0.1201 0.0437 0.1155
Echinococcus granulosus tm gpcr rhodopsin 0.1095 0.0398 0.105
Schistosoma mansoni neuropeptide receptor 0.1095 0.0398 0.118
Trichomonas vaginalis glucosylceramidase, putative 0.4113 0.1522 0.6546
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0514 0.0181 0.0181
Loa Loa (eye worm) melatonin receptor type 1A 0.1095 0.0398 0.0398
Echinococcus multilocularis lysosome membrane protein 2 0.0138 0.0041 0.0108
Loa Loa (eye worm) hypothetical protein 0.5817 0.2157 0.2157
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0006 0.0019
Schistosoma mansoni cpg binding protein 0.0031 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0127 0.0037 0.0168
Onchocerca volvulus 0.1095 0.0398 0.1544
Echinococcus multilocularis fucosidase, alpha L 1, tissue 0.8286 0.3077 0.8126
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0227 0.0074 0.0196
Trichomonas vaginalis glycogen debranching enzyme, putative 0.0728 0.0261 0.1122
Trichomonas vaginalis alpha-glucosidase, putative 0.1168 0.0425 0.1826
Trichomonas vaginalis glucosylceramidase, putative 0.4113 0.1522 0.6546
Trypanosoma brucei protein kinase, putative 0.0054 0.001 0.0107
Schistosoma mansoni integrin alpha 0.0153 0.0047 0.0139
Leishmania major beta tubulin 0.1201 0.0437 0.473
Trichomonas vaginalis glucosylceramidase, putative 0.4113 0.1522 0.6546
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.1417 0.0518 0.1536
Schistosoma mansoni alpha-glucosidase 0.9073 0.337 1
Brugia malayi RNA binding protein 0.0064 0.0014 0.0014
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0017 0.0179
Echinococcus granulosus g protein coupled receptor 0.1095 0.0398 0.105
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0042 0.0005 0.5
Trichomonas vaginalis beta-mannosidase, putative 0.0318 0.0108 0.0465
Brugia malayi Zinc carboxypeptidase family protein 0.0038 0.0004 0.0004
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.4299 0.1591 0.1591
Brugia malayi hypothetical protein 0.0163 0.0051 0.0051
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0063 0.0013 0.0039
Echinococcus granulosus g protein coupled receptor 0.1095 0.0398 0.105
Toxoplasma gondii peptidase family M13 protein 0.5817 0.2157 1
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0093 0.0024 0.011
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.2507 0.0924 0.3972
Trichomonas vaginalis set domain proteins, putative 0.0265 0.0089 0.0381
Onchocerca volvulus 0.2882 0.1063 0.4128
Brugia malayi Eukaryotic aspartyl protease family protein 0.0093 0.0024 0.0024
Brugia malayi Glycosyl hydrolases family 38 protein 0.0146 0.0044 0.0044
Echinococcus multilocularis integrin alpha ps 0.0033 0.0002 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1095 0.0398 0.118
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0194 0.0062 0.0163
Loa Loa (eye worm) hypothetical protein 0.0143 0.0043 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.4334 0.1605 0.6901
Schistosoma mansoni hypothetical protein 0.0042 0.0005 0.0016
Brugia malayi hypothetical protein 0.0138 0.0041 0.0041
Loa Loa (eye worm) thioredoxin reductase 0.012 0.0035 0.0035
Echinococcus granulosus beta galactosidase 0.0834 0.03 0.0793
Echinococcus granulosus beta tubulin 0.1201 0.0437 0.1155
Plasmodium falciparum glutathione reductase 0.012 0.0035 0.0776
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0029 0.0001 0.0002
Echinococcus multilocularis lamin 0.0056 0.0011 0.0028
Trypanosoma cruzi lanosterol synthase, putative 0.0029 0.0001 0.0007
Echinococcus multilocularis 6 phosphofructokinase 0.0125 0.0036 0.0095
Trypanosoma cruzi trypanothione reductase, putative 0.012 0.0035 0.0374
Onchocerca volvulus 0.1095 0.0398 0.1544
Echinococcus multilocularis rhodopsin orphan GPCR 0.1095 0.0398 0.105
Echinococcus multilocularis lamin dm0 0.0056 0.0011 0.0028
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0042 0.0005 0.011
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0876 0.0316 0.1359
Loa Loa (eye worm) hypothetical protein 0.0136 0.004 0.004
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0001 0.0001
Echinococcus granulosus CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Schistosoma mansoni memapsin-2 (A01 family) 0.0093 0.0024 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0002 0.0007
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0002 0.0036
Loa Loa (eye worm) 6-phosphofructokinase 0.0125 0.0036 0.0036
Echinococcus granulosus thyrotropin releasing hormone receptor 0.1095 0.0398 0.105
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Trichomonas vaginalis beta-glucosidase, putative 0.0569 0.0202 0.0867
Trypanosoma brucei lanosterol synthase 0.0029 0.0001 0.0007
Echinococcus granulosus neuropeptides capa receptor 0.1095 0.0398 0.105
Trichomonas vaginalis alpha-glucosidase, putative 0.1168 0.0425 0.1826
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0152 0.0046 0.0199
Loa Loa (eye worm) hypothetical protein 0.44 0.1629 0.1629
Schistosoma mansoni adenoreceptor 0.1095 0.0398 0.118
Schistosoma mansoni hypothetical protein 0.0415 0.0144 0.0429
Echinococcus multilocularis fmrfamide receptor 0.1095 0.0398 0.105
Giardia lamblia Nuclear ATP/GTP-binding protein 0.0038 0.0004 0.0075
Loa Loa (eye worm) hypothetical protein 0.1168 0.0425 0.0425
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.001 0.0107
Echinococcus granulosus mannosyl oligosaccharide 12 alpha mannosidase 0.0152 0.0046 0.0122
Brugia malayi MAP kinase sur-1 0.0054 0.001 0.001
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0227 0.0074 0.022
Leishmania major beta tubulin 0.1201 0.0437 0.473
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.1095 0.0398 0.105
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0876 0.0316 0.1359
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0227 0.0074 0.0804
Echinococcus granulosus cytosolic carboxypeptidase protein 5 0.0038 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0169 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.5817 0.2157 0.2157
Echinococcus multilocularis 0.0036 0.0003 0.0008
Giardia lamblia Beta tubulin 0.1201 0.0437 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0005 0.0023
Echinococcus granulosus CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0084 0.0021 0.0021
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0024 0.0072
Trypanosoma cruzi protein farnesyltransferase, putative 0.0029 0.0001 0.0007
Schistosoma mansoni scavenger receptor class B type-2 (sr-B2) 0.0138 0.0041 0.0122
Echinococcus multilocularis dnaJ subfamily B 0.0415 0.0144 0.0381
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.6268 0.2325 0.2325
Plasmodium vivax aspartyl proteinase, putative 0.0093 0.0024 0.0543
Brugia malayi neuropeptide F receptor 0.1095 0.0398 0.0398
Brugia malayi brahma associated protein 60 kDa 0.0042 0.0005 0.0005
Entamoeba histolytica glycogen phosphorylase, putative 0.0323 0.011 0.1184
Loa Loa (eye worm) hypothetical protein 0.0143 0.0043 0.0043
Brugia malayi Zinc carboxypeptidase family protein 0.0038 0.0004 0.0004
Echinococcus multilocularis g-protein coupled receptor 0.1095 0.0398 0.105
Plasmodium falciparum plasmepsin IV 0.0394 0.0136 0.3108
Plasmodium vivax aspartyl protease, putative 0.0093 0.0024 0.0543
Echinococcus multilocularis endoplasmic reticulum mannosyl oligosaccharide 0.0152 0.0046 0.0122
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0002 0.0009
Onchocerca volvulus 0.0265 0.0089 0.0344
Loa Loa (eye worm) integrin alpha pat-2 0.0236 0.0078 0.0078
Trichomonas vaginalis tubulin, putative 0.1201 0.0437 0.188
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0152 0.0046 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.098 0.0355 0.1526
Echinococcus multilocularis dro:myosuppressin receptor 0.1095 0.0398 0.105
Echinococcus granulosus g-protein coupled receptor 0.1095 0.0398 0.105
Brugia malayi Zinc carboxypeptidase family protein 0.0038 0.0004 0.0004
Brugia malayi hypothetical protein 0.0093 0.0024 0.0024
Echinococcus granulosus alpha mannosidase 2 0.0033 0.0002 0.0006
Echinococcus granulosus G protein coupled receptor 139 0.1095 0.0398 0.105
Loa Loa (eye worm) alpha amylase 0.0084 0.0021 0.0021
Echinococcus multilocularis integrin alpha ps 0.0069 0.0015 0.004
Trichomonas vaginalis glucosylceramidase, putative 0.4113 0.1522 0.6546
Onchocerca volvulus 0.1095 0.0398 0.1544
Echinococcus granulosus non lysosomal glucosylceramidase 0.1103 0.0401 0.1058
Schistosoma mansoni hypothetical protein 0.1095 0.0398 0.118
Onchocerca volvulus Trehalase homolog 0.0143 0.0043 0.0167
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0063 0.0013 0.0035
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0394 0.0136 0.0629
Echinococcus multilocularis g protein coupled receptor 0.1095 0.0398 0.105
Echinococcus multilocularis CD36 class B scavenger receptor 0.0138 0.0041 0.0108
Schistosoma mansoni bile acid beta-glucosidase-related 0.1103 0.0401 0.1188
Brugia malayi G-protein coupled receptor 0.1095 0.0398 0.0398
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.1168 0.0425 0.4594
Loa Loa (eye worm) hypothetical protein 0.0744 0.0267 0.0267
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0007 0.0007
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0227 0.0074 0.0798
Chlamydia trachomatis glycogen phosphorylase 0.0323 0.011 1
Echinococcus multilocularis orexin receptor type 2 0.1095 0.0398 0.105
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0194 0.0062 0.0266
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Echinococcus multilocularis neuropeptide receptor 0.1095 0.0398 0.105
Schistosoma mansoni hypothetical protein 0.0042 0.0005 0.0016
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0029 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0033 0.0002 0.0006
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0014 0.0014
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.001 0.01
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0227 0.0074 0.0804
Loa Loa (eye worm) BEN-1 protein 0.1201 0.0437 0.0437
Loa Loa (eye worm) beta-tubulin 0.1201 0.0437 0.0437
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0811 0.0292 0.0771
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0042 0.0005 0.0056
Leishmania major beta tubulin 0.1201 0.0437 0.473
Trichomonas vaginalis alpha-glucosidase, putative 0.1168 0.0425 0.1826
Schistosoma mansoni brg-1 associated factor 0.0042 0.0005 0.0016
Echinococcus granulosus tar DNA binding protein 0.0064 0.0014 0.0036
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.1168 0.0425 0.4598
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.1095 0.0398 0.118
Echinococcus multilocularis ceramide glucosyltransferase 0.206 0.0757 0.1999
Echinococcus granulosus serotonin receptor 0.1095 0.0398 0.105
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0227 0.0074 0.0196
Echinococcus granulosus integrin alpha 3 0.0118 0.0033 0.0088
Toxoplasma gondii beta-tubulin, putative 0.1201 0.0437 0.2025
Loa Loa (eye worm) hypothetical protein 0.005 0.0008 0.0008
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.001 0.0107
Onchocerca volvulus 0.1095 0.0398 0.1544
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.5817 0.2157 0.64
Echinococcus multilocularis alpha glucosidase 0.0084 0.0021 0.0055
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0002 0.0006
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0042 0.0005 0.0105
Schistosoma mansoni ceramide glucosyltransferase 0.206 0.0757 0.2246
Toxoplasma gondii aspartyl protease 0.0093 0.0024 0.011
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Onchocerca volvulus 0.0093 0.0024 0.0095
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0194 0.0062 0.0062
Echinococcus multilocularis serotonin receptor 0.1095 0.0398 0.105
Mycobacterium ulcerans 6-phosphofructokinase 0.0125 0.0036 0.01
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Schistosoma mansoni neuropeptide receptor 0.1095 0.0398 0.118
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0042 0.0005 0.011
Loa Loa (eye worm) TRE-1 protein 0.0143 0.0043 0.0043
Onchocerca volvulus 0.0223 0.0073 0.0282
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.1095 0.0398 0.105
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Onchocerca volvulus 0.0143 0.0043 0.0167
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.0005 0.0013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1095 0.0398 0.118
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.001 0.0107
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.2507 0.0924 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.1095 0.0398 0.105
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Brugia malayi Dopamine receptor protein 2 0.1095 0.0398 0.0398
Schistosoma mansoni neuropeptide receptor 0.1095 0.0398 0.118
Giardia lamblia Nuclear ATP/GTP-binding protein 0.0038 0.0004 0.0075
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0029 0.0001 0.0002
Echinococcus multilocularis Tolloid protein 1 0.0327 0.0111 0.0294
Schistosoma mansoni peptide (allatostatin)-like receptor 0.1095 0.0398 0.118
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0004 0.0017
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0152 0.0046 0.0199
Brugia malayi G protein-coupled receptor F59B2.13 0.1095 0.0398 0.0398
Echinococcus granulosus ceramide glucosyltransferase 0.206 0.0757 0.1999
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0038 0.0004 0.0017
Onchocerca volvulus Glucosylceramidase homolog 0.4113 0.1522 0.5908
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0227 0.0074 0.0804
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Mycobacterium tuberculosis Probable oxidoreductase 0.0157 0.0048 0.0221
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0006 0.0015
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.001 0.001
Trichomonas vaginalis alpha-glucosidase, putative 0.1168 0.0425 0.1826
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0004 0.0004
Loa Loa (eye worm) zinc carboxypeptidase 0.0038 0.0004 0.0004
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0876 0.0316 0.1359
Brugia malayi hypothetical protein 0.005 0.0008 0.0008
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0042 0.0005 0.0049
Echinococcus granulosus g protein coupled receptor 0.1095 0.0398 0.105
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.001 0.0211
Loa Loa (eye worm) hypothetical protein 0.0094 0.0025 0.0025
Echinococcus multilocularis glycogen debranching enzyme 0.0728 0.0261 0.0689
Echinococcus multilocularis fmrfamide receptor 0.1095 0.0398 0.105
Loa Loa (eye worm) amylo-alpha-1,6-glucosidase 0.0354 0.0122 0.0122
Schistosoma mansoni subfamily M14A unassigned peptidase (M14 family) 0.0223 0.0073 0.0216
Echinococcus granulosus lysosomal alpha glucosidase 1.0191 0.3787 1
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0876 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0041 0.0005 0.0005
Brugia malayi CD36 family protein 0.0138 0.0041 0.0041
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0152 0.0046 0.0199
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.001 0.0026
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0042 0.0005 0.0022
Mycobacterium tuberculosis Trehalose synthase TreS 0.0084 0.0021 0.0094
Entamoeba histolytica alpha-1,2-mannosidase, putative 0.0881 0.0318 0.344
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) RNA binding protein 0.0064 0.0014 0.0014
Schistosoma mansoni opsin-like receptor 0.1095 0.0398 0.118
Echinococcus granulosus somatostatin receptor 0.1095 0.0398 0.105
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0663 0.0237 0.0702
Echinococcus granulosus SWI:SNF matrix associated 0.0042 0.0005 0.0014
Brugia malayi hypothetical protein 0.0138 0.0041 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1095 0.0398 0.118
Echinococcus multilocularis integrin alpha 3 0.0118 0.0033 0.0088
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0138 0.0041 0.0041
Leishmania major glycosyl hydrolase-like protein 0.1168 0.0425 0.4594
Loa Loa (eye worm) hypothetical protein 0.1095 0.0398 0.0398
Onchocerca volvulus 0.1095 0.0398 0.1544
Brugia malayi Nematode astacin protease protein 30 0.0041 0.0005 0.0005
Brugia malayi hypothetical protein 0.1095 0.0398 0.0398
Brugia malayi Trehalase family protein 0.005 0.0008 0.0008
Schistosoma mansoni peptidase 0.0038 0.0004 0.0012
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.0005 0.0005
Schistosoma mansoni glycogen phosphorylase 0.0323 0.011 0.0326
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0093 0.0024 0.0024
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.1095 0.0398 0.105
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0227 0.0074 0.0804
Echinococcus granulosus cytosolic carboxypeptidase 1 0.0038 0.0004 0.001

Activities

Activity type Activity value Assay description Source Reference
Ratio (functional) = 0.28 Ratio of GH release stimulated by 300 ug/kg of compound to that of GH release stimulated by 300 ug/kg of hexarelin in infant rat (sc injection) ChEMBL. 12646029

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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