Detailed information for compound 21932

Basic information

Technical information
  • TDR Targets ID: 21932
  • Name: N-[(2R)-1-[[(1R)-1-acetamido-2-(1H-indol-3-yl )ethyl]-methylamino]-3-(1H-indol-3-yl)-1-oxop ropan-2-yl]-2-amino-2-methylpropanamide
  • MW: 502.608 | Formula: C28H34N6O3
  • H donors: 5 H acceptors: 3 LogP: 2.43 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)N[C@H](N(C(=O)[C@H](NC(=O)C(N)(C)C)Cc1c[nH]c2c1cccc2)C)Cc1c[nH]c2c1cccc2
  • InChi: 1S/C28H34N6O3/c1-17(35)32-25(14-19-16-31-23-12-8-6-10-21(19)23)34(4)26(36)24(33-27(37)28(2,3)29)13-18-15-30-22-11-7-5-9-20(18)22/h5-12,15-16,24-25,30-31H,13-14,29H2,1-4H3,(H,32,35)(H,33,37)/t24-,25-/m1/s1
  • InChiKey: HZUSGMCOWKTQFO-JWQCQUIFSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(1R)-2-[[(1R)-1-acetamido-2-(1H-indol-3-yl)ethyl]-methyl-amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-2-amino-2-methyl-propanamide
  • N-[(1R)-2-[[(1R)-1-acetamido-2-(1H-indol-3-yl)ethyl]-methylamino]-1-(1H-indol-3-ylmethyl)-2-oxoethyl]-2-amino-2-methylpropanamide
  • N-[(2R)-1-[[(1R)-1-acetamido-2-(1H-indol-3-yl)ethyl]-methyl-amino]-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]-2-azanyl-2-methyl-propanamide
  • N-[(1R)-2-[[(1R)-1-acetamido-2-(1H-indol-3-yl)ethyl]-methyl-amino]-1-(1H-indol-3-ylmethyl)-2-keto-ethyl]-2-amino-2-methyl-propionamide
  • N-[(2R)-1-[[(1R)-1-acetamido-2-(1H-indol-3-yl)ethyl]-methyl-amino]-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]-2-amino-2-methyl-propanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0006 0.079
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.009 0.0085 0.0303
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.009 0.0085 0.0382
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.009 0.0085 0.0224
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.009 0.0085 0.0224
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0019 0.0002 0.0005
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0106 0.1637
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0023 0.0007 0.0102
Plasmodium falciparum transporter, putative 0.0025 0.0009 0.0804
Echinococcus granulosus rhodopsin orphan GPCR 0.009 0.0085 0.0303
Schistosoma mansoni biogenic amine (dopamine) receptor 0.009 0.0085 0.0382
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Echinococcus granulosus Tubulin beta 2C chain 0.0112 0.0112 0.0399
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0059 0.0049 0.1701
Echinococcus granulosus neuropeptide Y receptor 0.009 0.0085 0.0303
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0013 0.0535
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0013 0.044
Schistosoma mansoni amine GPCR 0.009 0.0085 0.0382
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0016 0.0544
Echinococcus granulosus tubulin alpha 3 chain 0.0059 0.0049 0.0172
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Brugia malayi Cation transporter family protein 0.0103 0.0101 0.0266
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0009 0.0024
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0023 0.0007 0.0017
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0036 0.0022 0.0099
Brugia malayi phosphofructokinase 0.0107 0.0106 0.0278
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0041 0.0028 0.0435
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.028 1
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.0066 0.0233
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0031 0.0016 0.0015
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0092 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0177 0.629
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0058
Plasmodium falciparum tubulin delta chain, putative 0.0022 0.0005 0.0427
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0001 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.009 0.0085 0.0382
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0007 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.009 0.0085 0.0382
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0009 0.0024
Entamoeba histolytica tubulin family protein 0.0112 0.0112 0.869
Onchocerca volvulus 0.009 0.0085 0.1726
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0025 0.0009 0.0038
Brugia malayi Tubulin alpha chain 0.0022 0.0005 0.0013
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0041 0.0028 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0036 0.0022 0.0058
Trypanosoma cruzi DNA topoisomerase II, putative 0.0031 0.0016 0.0251
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Echinococcus multilocularis dro:myosuppressin receptor 0.009 0.0085 0.0303
Mycobacterium ulcerans lipoprotein LpqF 0.0208 0.0226 0.0224
Trypanosoma brucei zeta tubulin, putative 0.0022 0.0005 0.0074
Brugia malayi putative neuropeptide receptor 0.009 0.0085 0.0224
Loa Loa (eye worm) alpha-tubulin 0.0059 0.0049 0.0127
Loa Loa (eye worm) hypothetical protein 0.0039 0.0025 0.0066
Onchocerca volvulus 0.009 0.0085 0.1726
Entamoeba histolytica heat shock protein 90, putative 0.0031 0.0016 0.1183
Loa Loa (eye worm) hypothetical protein 0.0074 0.0066 0.0174
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.009 0.0085 0.0303
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Brugia malayi Cytochrome P450 family protein 0.0069 0.0061 0.0161
Echinococcus granulosus sodium channel protein 0.0119 0.012 0.0425
Giardia lamblia Heat shock protein HSP 90-alpha 0.0031 0.0016 0.1348
Echinococcus granulosus g-protein coupled receptor 0.009 0.0085 0.0303
Onchocerca volvulus 0.0103 0.0101 0.2049
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0023 0.0007 0.0023
Echinococcus granulosus glycine receptor subunit alpha 1 0.0103 0.0101 0.0359
Plasmodium vivax tubulin alpha chain, putative 0.0059 0.0049 0.4315
Echinococcus multilocularis tubulin beta 1 chain 0.0112 0.0112 0.0399
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0038 0.1333
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0025 0.0009 0.003
Schistosoma mansoni tubulin subunit alpha 0.0022 0.0005 0.0021
Trichomonas vaginalis tubulin beta chain, putative 0.0059 0.0049 0.1701
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0048 0.0035 0.0093
Trypanosoma brucei zeta tubulin 0.0022 0.0005 0.0074
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0041 0.0028 0.0027
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0031 0.0016 0.031
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0036 0.0022 0.0058
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0065 0.0057 0.0057
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0106 0.3758
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0025 0.0009 0.0267
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.028 1
Brugia malayi heat shock protein 90 0.0031 0.0016 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0005 0.0023
Trichomonas vaginalis tubulin, putative 0.0028 0.0013 0.0412
Echinococcus granulosus heat shock protein 90 0.0031 0.0016 0.0058
Mycobacterium ulcerans DNA gyrase subunit B 0.0031 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Trichomonas vaginalis tubulin gamma chain, putative 0.005 0.0038 0.1333
Echinococcus granulosus voltage gated potassium channel 0.0032 0.0016 0.0058
Giardia lamblia Neurogenic locus notch-like protein 0.0104 0.0103 0.9124
Plasmodium vivax vivapain-2 0.0019 0.0001 0.0097
Giardia lamblia Epsilon tubulin 0.0022 0.0005 0.0318
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.005 0.0049
Onchocerca volvulus 0.0025 0.0009 0.0162
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0023 0.0007 0.003
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Brugia malayi ORL1-like opioid receptor 0.009 0.0085 0.0224
Trichomonas vaginalis tubulin epsilon chain, putative 0.0059 0.0049 0.1701
Giardia lamblia Delta tubulin 0.0022 0.0005 0.0318
Trypanosoma brucei alpha tubulin, putative 0.0028 0.0013 0.0195
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0001 0.0004
Plasmodium falciparum alpha tubulin 2 0.0059 0.0049 0.4315
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0025 0.0089
Schistosoma mansoni pyruvate dehydrogenase 0.0532 0.061 0.2725
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0031 0.0016 0.0016
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0103 0.0101 0.0266
Plasmodium falciparum alpha tubulin 1 0.0059 0.0049 0.4315
Loa Loa (eye worm) acetylcholine receptor protein 0.0048 0.0035 0.0093
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0015 0.0601
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0023 0.0007 0.0102
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.009 0.0085 0.0303
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0096 0.0251
Trypanosoma cruzi zeta tubulin, putative 0.0022 0.0005 0.0074
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0031 0.0016 0.0011
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0104 0.0103 0.3644
Trypanosoma brucei poly(adp-ribose) polymerase 0.007 0.0062 0.0952
Toxoplasma gondii beta-1 tubulin, putative 0.0112 0.0112 0.4504
Schistosoma mansoni lipoxygenase 0.0232 0.0255 0.1138
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0058
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0006 0.0255
Echinococcus granulosus g protein coupled receptor 0.009 0.0085 0.0303
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0208 0.0226 0.0226
Loa Loa (eye worm) cysteine protease 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0198
Mycobacterium leprae Probable two component sensor kinase MprB 0.0031 0.0016 0.0011
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0022 0.0005 0.0192
Echinococcus granulosus lamin 0.0086 0.0081 0.0289
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0022 0.0078
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Echinococcus granulosus cathepsin l1 0.0019 0.0001 0.0004
Echinococcus granulosus p2X purinoceptor 4 0.0077 0.0071 0.0252
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0028 0.0101
Loa Loa (eye worm) cytochrome P450 family protein 0.0105 0.0104 0.0272
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0119 0.012 0.0425
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0068 0.006 0.2109
Toxoplasma gondii thioredoxin reductase 0.0038 0.0024 0.0948
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0013 0.0046
Loa Loa (eye worm) glutathione reductase 0.0038 0.0024 0.0062
Trichomonas vaginalis tubulin alpha chain, putative 0.0028 0.0013 0.0412
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0025 0.0009 0.0267
Schistosoma mansoni tubulin subunit beta 0.0112 0.0112 0.0503
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0096 0.0251
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0106 0.0278
Trichomonas vaginalis tubulin beta chain, putative 0.0059 0.0049 0.1701
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0031 0.0016 0.0651
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0025 0.0009 0.0022
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Plasmodium vivax tubulin epsilon chain, putative 0.005 0.0038 0.3404
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0006 0.0005
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Echinococcus multilocularis g protein coupled receptor 0.009 0.0085 0.0303
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0027 0.0011 0.0039
Echinococcus granulosus cpg binding protein 0.003 0.0014 0.0051
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0106 0.8178
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0022 0.0058
Plasmodium falciparum heat shock protein 90 0.0031 0.0016 0.1446
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0106 0.0278
Trypanosoma brucei heat shock protein 90, putative 0.0031 0.0016 0.0251
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0086 0.0384
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0024
Schistosoma mansoni cytochrome P450 0.0041 0.0028 0.0126
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0027 0.0011 0.017
Brugia malayi Tubulin beta-1 chain 0.0112 0.0112 0.0295
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0031 0.0016 0.0016
Leishmania major delta tubulin, putative 0.0022 0.0005 0.0074
Leishmania major DNA topoisomerase ii 0.0031 0.0016 0.0251
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0025 0.0009 0.0038
Loa Loa (eye worm) hypothetical protein 0.0056 0.0045 0.0118
Echinococcus multilocularis heat shock protein 0.0031 0.0016 0.0058
Onchocerca volvulus 0.0025 0.0009 0.0162
Brugia malayi WGR domain containing protein 0.007 0.0062 0.0161
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0232 0.0255 0.0903
Brugia malayi Cathepsin L-like precursor 0.0019 0.0001 0.0003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0016 0.0042
Leishmania major gamma-tubulin 0.005 0.0038 0.0592
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.0016 0.0251
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Schistosoma mansoni opsin-like receptor 0.009 0.0085 0.0382
Mycobacterium ulcerans cell division protein FtsZ 0.0022 0.0005 0.0004
Echinococcus granulosus glycine receptor subunit alpha 1 0.0103 0.0101 0.0359
Onchocerca volvulus 0.0236 0.0259 0.5273
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.009 0.0085 0.0382
Trypanosoma cruzi epsilon tubulin, putative 0.005 0.0038 0.0592
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0025 0.0986
Echinococcus granulosus slit 2 protein 0.0023 0.0007 0.0024
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0119 0.012 0.1854
Brugia malayi Thioredoxin reductase 0.0038 0.0024 0.0062
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0031 0.0016 0.0251
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0031 0.0016 0.0973
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0013 0.1189
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0041 0.0028 0.0027
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0048 0.0035 0.0093
Schistosoma mansoni heat shock protein 0.0031 0.0016 0.0073
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0034 0.0089
Loa Loa (eye worm) G-protein coupled receptor 0.009 0.0085 0.0224
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0025 0.0089
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0032 0.0016 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.009 0.0085 0.0382
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0027 0.0011 0.017
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0009 0.004
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0001 0.0113
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0092 0.0087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0022 0.0078
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0025 0.0009 0.003
Echinococcus granulosus adam 0.0104 0.0103 0.0364
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.009 0.0085 0.0224
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.005 0.0049
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0023 0.0007 0.0102
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0006 0.0002
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0081 0.0081
Trypanosoma cruzi tubulin gamma chain 0.005 0.0038 0.0592
Trichomonas vaginalis tubulin alpha chain, putative 0.0028 0.0013 0.0412
Leishmania major cAMP-specific phosphodiesterase, putative 0.0023 0.0007 0.0102
Trichomonas vaginalis tubulin beta chain, putative 0.0059 0.0049 0.1701
Echinococcus multilocularis p2X purinoceptor 4 0.0077 0.0071 0.0252
Trichomonas vaginalis tubulin, putative 0.0112 0.0112 0.3993
Schistosoma mansoni neuropeptide F-like receptor 0.009 0.0085 0.0382
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0005
Plasmodium falciparum DNA gyrase subunit B 0.0031 0.0016 0.1446
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0101 0.0266
Onchocerca volvulus 0.009 0.0085 0.1726
Entamoeba histolytica hypothetical protein 0.0083 0.0077 0.5934
Echinococcus multilocularis fmrfamide receptor 0.009 0.0085 0.0303
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0177 0.629
Loa Loa (eye worm) ACC-1 protein 0.0103 0.0101 0.0266
Treponema pallidum sodium- and chloride- dependent transporter 0.0149 0.0155 1
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0007 0.0102
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0103 0.0101 0.0453
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0024 0.0007 0.0225
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0063 0.0972
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0025 0.2238
Trichomonas vaginalis tubulin beta chain, putative 0.0059 0.0049 0.1701
Echinococcus granulosus fmrfamide receptor 0.009 0.0085 0.0303
Brugia malayi G-protein coupled receptor 0.009 0.0085 0.0224
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0031 0.0016 0.2326
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Leishmania major mitochondrial DNA topoisomerase II 0.0031 0.0016 0.0251
Entamoeba histolytica hypothetical protein 0.0056 0.0045 0.3421
Brugia malayi Dopamine receptor 0.009 0.0085 0.0224
Plasmodium falciparum glutathione reductase 0.0038 0.0024 0.2105
Brugia malayi CXXC zinc finger family protein 0.0028 0.0013 0.0033
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0023 0.0007 0.003
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0051 0.023
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0041 0.0028 0.0028
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0023 0.0007 0.0018
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0316 0.0354 0.0928
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0032
Echinococcus granulosus lamin dm0 0.0086 0.0081 0.0289
Echinococcus granulosus biogenic amine 5HT receptor 0.0209 0.0228 0.0807
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0031 0.0016 0.0016
Echinococcus granulosus poly (ADP ribose) polymerase 0.002 0.0002 0.0009
Brugia malayi steroid hormone receptor 0.0036 0.0022 0.0058
Onchocerca volvulus 0.002 0.0003 0.0039
Brugia malayi flavodoxin family protein 0.0027 0.0011 0.0029
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.009 0.0085 0.0303
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0036 0.0022 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0001 0.0003
Echinococcus granulosus tubulin alpha 1C chain 0.0059 0.0049 0.0172
Brugia malayi Cathepsin L-like precursor 0.0019 0.0001 0.0003
Toxoplasma gondii hypothetical protein 0.0104 0.0103 0.4114
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0103 0.0101 0.0359
Trichomonas vaginalis hypothetical protein 0.0104 0.0103 0.3644
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0081 0.0081
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0208 0.0226 0.0221
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0015 0.0067
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0056 0.0045 0.0118
Brugia malayi laminin-like protein K08C7.3 precursor 0.0023 0.0007 0.0018
Trypanosoma brucei alpha tubulin 0.0059 0.0049 0.075
Echinococcus granulosus FTZ F1 alpha 0.0036 0.0022 0.0078
Echinococcus granulosus sex peptide receptor 0.009 0.0085 0.0303
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0024 0.0062
Plasmodium falciparum phosphodiesterase gamma, putative 0.0023 0.0007 0.0589
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0041 0.0028 0.0028
Brugia malayi Serotonin/octopamine receptor family protein 7 0.009 0.0085 0.0224
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0041 0.0028 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0103 0.0101 0.0453
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Trypanosoma brucei beta tubulin 0.0112 0.0112 0.1739
Onchocerca volvulus Neuropeptide F receptor homolog 0.009 0.0085 0.1726
Plasmodium falciparum DNA topoisomerase 2 0.0031 0.0016 0.1446
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0041 0.0028 0.0027
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0066 0.2317
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0048 0.0035 0.0093
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0022 0.0005 0.0549
Onchocerca volvulus 0.0039 0.0025 0.0492
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0025 0.0089
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0041 0.0028 0.0027
Brugia malayi G protein-coupled receptor F59B2.13 0.009 0.0085 0.0224
Mycobacterium ulcerans two component sensor kinase MprB 0.0031 0.0016 0.0015
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0228 0.025 1
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0027 0.0011 0.0039
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0001 0.0004
Echinococcus granulosus Tubulin beta 2C chain 0.0112 0.0112 0.0399
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.009 0.0085 0.0303
Onchocerca volvulus 0.009 0.0085 0.1726
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0103 0.0101 0.0359
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0083 0.0078 0.0204
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0106 0.0278
Trypanosoma brucei Heat shock protein 83, putative 0.0031 0.0016 0.0251
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Schistosoma mansoni P2X receptor subunit 0.0077 0.0071 0.0317
Echinococcus granulosus G protein coupled receptor 139 0.009 0.0085 0.0303
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0027 0.0011 0.0979
Schistosoma mansoni neurotransmitter gated ion channel 0.0048 0.0035 0.0159
Echinococcus multilocularis tubulin subunit TubB 0.0059 0.0049 0.0172
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0103 0.0101 0.0359
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0013 0.044
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0013 0.708
Echinococcus multilocularis Tubulin beta 2C chain 0.0112 0.0112 0.0399
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0187 0.6671
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0016 0.0074
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0031 0.0016 0.0251
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0013 0.044
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0023 0.0007 0.003
Loa Loa (eye worm) hypothetical protein 0.0104 0.0103 0.0269
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0009 0.0024
Echinococcus granulosus tubulin alpha 3 chain 0.0059 0.0049 0.0172
Schistosoma mansoni cpg binding protein 0.0028 0.0013 0.0056
Trypanosoma brucei heat shock protein, putative 0.0031 0.0016 0.0251
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0002 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.005 0.005
Echinococcus multilocularis rhodopsin orphan GPCR 0.009 0.0085 0.0303
Loa Loa (eye worm) tubulin beta chain 0.0112 0.0112 0.0295
Echinococcus multilocularis neuropeptide receptor 0.009 0.0085 0.0303
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0025 0.0009 0.0038
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0048 0.0035 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0031 0.0016 0.0015
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0103 0.0101 0.0266
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0041 0.0028 0.0028
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0031 0.0016 0.0043
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0066 0.1016
Onchocerca volvulus 0.009 0.0085 0.1726
Loa Loa (eye worm) ACC-1 protein 0.0103 0.0101 0.0266
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0023 0.0007 0.0023
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0048 0.0035 0.0093
Brugia malayi AKH receptor 0.009 0.0085 0.0224
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0092 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0041 0.0028 0.0028
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Onchocerca volvulus 0.0103 0.0101 0.2049
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.009 0.0085 0.0382
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.005 0.0038 0.1533
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0009 0.004
Echinococcus granulosus neurogenic locus notch protein 0.0023 0.0007 0.0024
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0037 0.0023 0.078
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0036 0.0022 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0036 0.0022 0.0058
Brugia malayi sulfakinin receptor protein 0.009 0.0085 0.0224
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Loa Loa (eye worm) integrin beta-2 0.3234 0.3814 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Giardia lamblia Hypothetical protein 0.0023 0.0007 0.0481
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0031 0.0016 0.0016
Echinococcus granulosus dnaJ subfamily B 0.0402 0.0456 0.1616
Schistosoma mansoni alpha-1 adrenergic receptor 0.009 0.0085 0.0382
Schistosoma mansoni thyroid hormone receptor 0.0036 0.0022 0.0099
Echinococcus granulosus 7tm_1 domain containing protein 0.009 0.0085 0.0303
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.009 0.0085 0.0224
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Plasmodium vivax glutathione reductase, putative 0.0038 0.0024 0.2105
Schistosoma mansoni tubulin subunit alpha 0.0059 0.0049 0.0217
Brugia malayi Kelch motif family protein 0.0491 0.0562 0.1473
Echinococcus multilocularis thyroid hormone receptor alpha 0.0036 0.0022 0.0078
Echinococcus granulosus Tubulin alpha 1 chain 0.0059 0.0049 0.0172
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0048 0.0035 0.0093
Echinococcus multilocularis neuropeptide receptor A26 0.009 0.0085 0.0303
Plasmodium vivax endoplasmin, putative 0.0031 0.0016 0.1446
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0048 0.0035 0.0093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.009 0.0085 0.0382
Schistosoma mansoni polycystin 1-related 0.0039 0.0025 0.0112
Echinococcus multilocularis GPCR, family 2 0.0031 0.0016 0.0057
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0009 0.0362
Echinococcus granulosus tubulin gamma 1 chain 0.005 0.0038 0.0136
Brugia malayi Probable DNA topoisomerase II 0.0031 0.0016 0.0043
Trichomonas vaginalis endoplasmin, putative 0.0031 0.0016 0.0544
Trypanosoma cruzi Heat shock protein 83, putative 0.0031 0.0016 0.0251
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Schistosoma mansoni rhodopsin-like orphan GPCR 0.009 0.0085 0.0382
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0036 0.0022 0.0078
Leishmania major hypothetical protein, conserved 0.0031 0.0016 0.0251
Echinococcus granulosus tubulin alpha chain 0.0059 0.0049 0.0172
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.009 0.0085 0.0303
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0031 0.0016 0.0016
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0001 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0015 0.0067
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.007 0.0062 0.0952
Echinococcus multilocularis adam 0.0104 0.0103 0.0364
Brugia malayi Pre-SET motif family protein 0.003 0.0015 0.0039
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0106 0.0105
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0025 0.0009 0.0032
Schistosoma mansoni DNA topoisomerase II 0.0031 0.0016 0.0073
Onchocerca volvulus 0.0086 0.0081 0.1642
Echinococcus multilocularis sodium channel protein 0.0119 0.012 0.0425
Schistosoma mansoni P2X receptor subunit 0.0077 0.0071 0.0317
Echinococcus multilocularis rhodopsin orphan GPCR 0.009 0.0085 0.0303
Brugia malayi EGF-like domain containing protein 0.0023 0.0007 0.0018
Loa Loa (eye worm) LGC-31 protein 0.0103 0.0101 0.0266
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.009 0.0085 0.0303
Schistosoma mansoni biogenic amine receptor 0.009 0.0085 0.0382
Trypanosoma cruzi p450 reductase, putative 0.0027 0.0011 0.017
Onchocerca volvulus Protein ultraspiracle homolog 0.0036 0.0022 0.0429
Trypanosoma brucei tubulin gamma chain 0.005 0.0038 0.0592
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0106 0.1637
Brugia malayi 6-phosphofructokinase 0.0107 0.0106 0.0278
Echinococcus multilocularis 0.0041 0.0028 0.01
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.009 0.0085 0.0224
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0023 0.0007 0.0589
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0009 0.0804
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.0066 0.5042
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0083 0.0078 0.0276
Schistosoma mansoni tubulin subunit epsilon 0.005 0.0038 0.0171
Brugia malayi Cathepsin L-like precursor 0.0019 0.0001 0.0003
Echinococcus granulosus integrin beta 2 0.2396 0.282 1
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0023 0.0007 0.0023
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0031 0.0016 0.0251
Loa Loa (eye worm) alpha-tubulin 0.0059 0.0049 0.0127
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.009 0.0085 0.0382
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.0056 0.0045 0.0118
Echinococcus granulosus allatostatin A receptor 0.009 0.0085 0.0303
Schistosoma mansoni hypothetical protein 0.0402 0.0456 0.2036
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.009 0.0085 0.0382
Echinococcus granulosus tubulin alpha 0.005 0.0038 0.0136
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.009 0.0085 0.0303
Echinococcus multilocularis rhodopsin orphan GPCR 0.009 0.0085 0.0303
Loa Loa (eye worm) hypothetical protein 0.0497 0.0568 0.149
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0025 0.0009 0.0032
Trichomonas vaginalis tubulin alpha chain, putative 0.0028 0.0013 0.0412
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0041 0.0028 0.0027
Echinococcus multilocularis tachykinin peptides receptor 99D 0.009 0.0085 0.0303
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Echinococcus multilocularis plexin a4 0.0024 0.0007 0.0026
Brugia malayi Dopamine receptor protein 2 0.009 0.0085 0.0224
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0036 0.0022 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.009 0.0085 0.0382
Leishmania major cathepsin L-like protease 0.0019 0.0001 0.0017
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.005 0.0177
Brugia malayi Cytochrome P450 family protein 0.0041 0.0028 0.0074
Trypanosoma cruzi heat shock protein 90, putative 0.0031 0.0016 0.0251
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0022
Echinococcus multilocularis Tubulin beta 2C chain 0.0112 0.0112 0.0399
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0001 0.0097
Brugia malayi Tubulin alpha-2 chain 0.0059 0.0049 0.0127
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Schistosoma mansoni tubulin subunit beta 0.0112 0.0112 0.0503
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0025 0.0009 0.003
Schistosoma mansoni tubulin subunit beta 0.0112 0.0112 0.0503
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0041 0.0028 0.0028
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0025 0.0009 0.0038
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0127 0.0129 0.0458
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0103 0.0101 0.0359
Plasmodium vivax delta tubulin, putative 0.0022 0.0005 0.0427
Loa Loa (eye worm) TOPoisomerase family member 0.0031 0.0016 0.0043
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Echinococcus multilocularis neuropeptide FF receptor 2 0.009 0.0085 0.0303
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.009 0.0085 0.0224
Trypanosoma brucei beta lactamase 0.0208 0.0226 0.3489
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0066 0.1016
Trypanosoma cruzi tubulin delta chain 0.0022 0.0005 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0036 0.0022 0.0058
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0106 0.0101
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0009 0.004
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Toxoplasma gondii heat shock protein 90, putative 0.0031 0.0016 0.0651
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Schistosoma mansoni tubulin subunit beta 0.0112 0.0112 0.0503
Trichomonas vaginalis DNA topoisomerase II, putative 0.0031 0.0016 0.0544
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0904 0.1051 0.3728
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0106 0.8178
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0177 0.3587
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Schistosoma mansoni hypothetical protein 0.0067 0.0059 0.0264
Echinococcus granulosus poly adp ribose polymerase 2 0.007 0.0062 0.0218
Onchocerca volvulus 0.0056 0.0045 0.0896
Brugia malayi Cathepsin L-like precursor 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0877 0.1019 0.2671
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0041 0.0028 0.0028
Trypanosoma cruzi alpha tubulin, putative 0.0059 0.0049 0.075
Echinococcus granulosus tubulin subunit TubB 0.0059 0.0049 0.0172
Onchocerca volvulus 0.009 0.0085 0.1726
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0022 0.0078
Echinococcus multilocularis hypothetical protein 0.0059 0.0049 0.0172
Mycobacterium leprae Conserved hypothetical protein 0.0041 0.0028 0.0023
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0009 0.0032
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0491 0.0562 0.1473
Echinococcus multilocularis tubulin alpha 3 chain 0.0059 0.0049 0.0172
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0024
Plasmodium vivax amine transporter, putative 0.0025 0.0009 0.0804
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0013 0.044
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Brugia malayi hypothetical protein 0.0019 0.0002 0.0005
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0023 0.0007 0.0589
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0081 0.0081
Toxoplasma gondii DNA topoisomerase 2, putative 0.0031 0.0016 0.0651
Schistosoma mansoni nAChR subunit 0.0103 0.0101 0.0453
Leishmania major hypothetical protein, conserved 0.0023 0.0007 0.0102
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0009 0.0362
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0023 0.0007 0.0102
Schistosoma mansoni hypothetical protein 0.0031 0.0016 0.0072
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0056 0.0045 0.0201
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0106 0.3758
Onchocerca volvulus 0.0104 0.0103 0.2078
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0031 0.0016 0.2326
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0103 0.0101 0.0359
Echinococcus multilocularis protein jagged 2 0.0104 0.0103 0.0364
Echinococcus granulosus intermediate filament protein 0.0086 0.0081 0.0289
Brugia malayi Endoplasmin precursor 0.0031 0.0016 0.0043
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0103 0.0101 0.0266
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0001 0.0005
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0031 0.0016 0.0016
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0103 0.0101 0.0266
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0013 0.0535
Loa Loa (eye worm) tubulin gamma chain 0.005 0.0038 0.01
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Brugia malayi kinase, mitochondrial precursor 0.0563 0.0647 0.1696
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0007 0.0102
Echinococcus multilocularis neuropeptide s receptor 0.009 0.0085 0.0303
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0197 0.0213 0.3286
Brugia malayi putative neuropeptide receptor NPR1 0.009 0.0085 0.0224
Echinococcus multilocularis tubulin alpha chain 0.0059 0.0049 0.0172
Entamoeba histolytica tubulin alpha-1 chain 0.0059 0.0049 0.3701
Schistosoma mansoni tubulin subunit beta 0.0022 0.0005 0.0021
Echinococcus granulosus geminin 0.0524 0.06 0.2128
Trypanosoma brucei heat shock protein, putative 0.0031 0.0016 0.0251
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0013 0.044
Schistosoma mansoni cpg binding protein 0.003 0.0014 0.0065
Schistosoma mansoni neurotransmitter gated ion channel 0.0056 0.0045 0.0201
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0031 0.0016 0.0016
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0009 0.0024
Echinococcus granulosus glycine receptor subunit alpha 1 0.0103 0.0101 0.0359
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0036 0.0022 0.0058
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0023 0.0007 0.0023
Entamoeba histolytica tubulin family protein 0.0112 0.0112 0.869
Brugia malayi Tubulin alpha chain 0.0059 0.0049 0.0127
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.0066 0.2631
Onchocerca volvulus 0.0036 0.0022 0.0429
Schistosoma mansoni hypothetical protein 0.009 0.0085 0.0382
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0006 0.033
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Leishmania major cytochrome p450-like protein 0.0041 0.0028 0.0435
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.009 0.0085 0.1726
Loa Loa (eye worm) hypothetical protein 0.0082 0.0076 0.0199
Trypanosoma brucei alpha tubulin 0.0059 0.0049 0.075
Brugia malayi tubulin alpha-2 chain 0.0059 0.0049 0.0127
Loa Loa (eye worm) hypothetical protein 0.0104 0.0103 0.0269
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0041 0.0028 0.0435
Trichomonas vaginalis tubulin beta chain, putative 0.0112 0.0112 0.3993
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0103 0.0101 0.0359
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0103 0.0101 0.0359
Mycobacterium tuberculosis Cell division protein FtsZ 0.0022 0.0005 0.0005
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0023 0.0007 0.0023
Plasmodium vivax DNA topoisomerase II, putative 0.0031 0.0016 0.1446
Brugia malayi Cell division protein ftsZ 0.0022 0.0005 0.0013
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0103 0.0101 0.0266
Trichomonas vaginalis receptor histidine kinase, putative 0.0031 0.0016 0.0544
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0023 0.0007 0.003
Echinococcus multilocularis neuropeptide Y receptor 0.009 0.0085 0.0303
Trypanosoma brucei heat shock protein, putative 0.0031 0.0016 0.0251
Echinococcus multilocularis Tubulin beta 2C chain 0.0112 0.0112 0.0399
Plasmodium vivax vivapain-2 0.0019 0.0001 0.0097
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0127 0.0129 1
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0031 0.0016 0.0043
Schistosoma mansoni alpha tubulin 0.0059 0.0049 0.0217
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.0066 0.2317
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0103 0.0101 0.0266
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0187 0.6671
Echinococcus granulosus g protein coupled receptor 0.009 0.0085 0.0303
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0036 0.0022 0.0099
Giardia lamblia High cysteine protein 0.0104 0.0103 0.9124
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Giardia lamblia hypothetical protein 0.0023 0.0007 0.0481
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0039
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0023 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Leishmania major cathepsin L-like protease 0.0071 0.0063 0.0972
Trypanosoma brucei heat shock protein 90, putative 0.0031 0.0016 0.0251
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0101 0.0266
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0058
Brugia malayi photoreceptor-specific nuclear receptor 0.0036 0.0022 0.0058
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0036 0.0022 0.0078
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.009 0.0085 0.0382
Schistosoma mansoni growth hormone secretagogue receptor 0.009 0.0085 0.0382
Schistosoma mansoni neuropeptide f receptor 76f 0.009 0.0085 0.0382
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.007
Onchocerca volvulus 0.009 0.0085 0.1726
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0023 0.0007 0.003
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0036 0.0022 0.0099
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0006 0.0098
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0027 0.0011 0.017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.0043
Schistosoma mansoni hypothetical protein 0.0031 0.0016 0.0072
Brugia malayi ecdysteroid receptor 0.0036 0.0022 0.0058
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0877 0.1019 0.2671
Echinococcus granulosus tubulin alpha chain 0.0059 0.0049 0.0172
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Schistosoma mansoni thyroid hormone receptor 0.0036 0.0022 0.0099
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.005 0.0177
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0023 0.0007 0.0023
Giardia lamblia Beta tubulin 0.0112 0.0112 1
Echinococcus granulosus dro:myosuppressin receptor 0.009 0.0085 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.0133
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0177 0.629
Echinococcus multilocularis pikachurin 0.0023 0.0007 0.0024
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0132 0.0135 0.5412
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0031 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0058
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0015 0.0053
Brugia malayi GnHR receptor homolog 0.009 0.0085 0.0224
Echinococcus granulosus neuropeptide FF receptor 2 0.009 0.0085 0.0303
Loa Loa (eye worm) G-protein coupled receptor 0.009 0.0085 0.0224
Echinococcus granulosus Tubulin beta 2C chain 0.0112 0.0112 0.0399
Entamoeba histolytica hypothetical protein 0.0083 0.0077 0.5934
Loa Loa (eye worm) tubulin alpha chain 0.0059 0.0049 0.0127
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0056 0.0045 0.0118
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0016 0.0074
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Echinococcus multilocularis tubulin alpha chain 0.0059 0.0049 0.0172
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0001 0.0017
Trypanosoma brucei beta tubulin 0.0112 0.0112 0.1739
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Loa Loa (eye worm) hypothetical protein 0.0086 0.0081 0.0213
Loa Loa (eye worm) hypothetical protein 0.0096 0.0093 0.0245
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0023 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0025 0.0089
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0001 0.0017
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0103 0.0101 0.0359
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0362 0.0409 0.1071
Onchocerca volvulus 0.0103 0.0101 0.2049
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0056 0.0045 0.0118
Schistosoma mansoni neuropeptide F-like receptor 0.009 0.0085 0.0382
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0041 0.0028 0.0027
Echinococcus granulosus peptide allatostatin:somatostatin 0.009 0.0085 0.0303
Echinococcus multilocularis p2X purinoceptor 4 0.0077 0.0071 0.0252
Echinococcus multilocularis glycine receptor subunit beta 0.0103 0.0101 0.0359
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0013 0.0033
Trichomonas vaginalis tubulin alpha chain, putative 0.0112 0.0112 0.3993
Echinococcus granulosus tm gpcr rhodopsin 0.009 0.0085 0.0303
Leishmania major cathepsin L-like protease 0.0019 0.0001 0.0017
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0041 0.0028 0.0027
Schistosoma mansoni nAChR subunit 0.0103 0.0101 0.0453
Brugia malayi cytochrome P450 0.0041 0.0028 0.0074
Toxoplasma gondii cytochrome p450 superfamily protein 0.0041 0.0028 0.1128
Brugia malayi Intermediate filament tail domain containing protein 0.0086 0.0081 0.0213
Echinococcus multilocularis Tubulin alpha 1 chain 0.0059 0.0049 0.0172
Echinococcus granulosus tubulin beta 1 chain 0.0112 0.0112 0.0399
Trichomonas vaginalis tubulin beta chain, putative 0.0059 0.0049 0.1701
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0024
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0041 0.0028 0.0027
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0029 0.0014 0.0048
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Schistosoma mansoni biogenic amine (5HT) receptor 0.0209 0.0228 0.1017
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.003 0.0015 0.05
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0041 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0031 0.0016 0.0016
Leishmania major zeta tubulin, putative 0.0022 0.0005 0.0074
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Echinococcus granulosus neuropeptide s receptor 0.009 0.0085 0.0303
Plasmodium vivax phosphodiesterase gamma, putative 0.0023 0.0007 0.0589
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0041 0.0028 0.0027
Trypanosoma brucei beta tubulin 0.005 0.0038 0.0592
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0197 0.0213 0.3286
Toxoplasma gondii alpha tubulin TUBA1 0.0059 0.0049 0.1944
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0036 0.0022 0.0099
Leishmania major C-8 sterol isomerase-like protein 0.0362 0.0409 0.6317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Brugia malayi follicle stimulating hormone receptor 0.0316 0.0354 0.0928
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.009 0.0085 0.0303
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Plasmodium vivax heat shock protein 86, putative 0.0031 0.0016 0.1446
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.005 0.0038 0.01
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Onchocerca volvulus 0.0028 0.0013 0.0235
Trypanosoma brucei heat shock protein, putative 0.0031 0.0016 0.0251
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.007 0.0062 0.0218
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.009 0.0085 0.0303
Onchocerca volvulus 0.0149 0.0155 0.3154
Echinococcus multilocularis rhodopsin orphan GPCR 0.009 0.0085 0.0303
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0017
Loa Loa (eye worm) tubulin beta-1 chain 0.0112 0.0112 0.0295
Toxoplasma gondii cathepsin CPL 0.0019 0.0001 0.0044
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.0066 0.0233
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Schistosoma mansoni plexin 0.002 0.0003 0.0013
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Echinococcus granulosus beta tubulin 0.0112 0.0112 0.0399
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0001 0.0005
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0103 0.0101 0.0266
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0177 0.629
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0009 0.0032
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0023 0.0007 0.0102
Loa Loa (eye worm) beta-tubulin 0.0112 0.0112 0.0295
Schistosoma mansoni sodium/chloride dependent transporter 0.0149 0.0155 0.0694
Plasmodium falciparum tubulin beta chain 0.0112 0.0112 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0103 0.0101 0.0359
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0102
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0563 0.0647 0.2294
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0009 0.004
Schistosoma mansoni pyruvate dehydrogenase 0.0563 0.0647 0.2891
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.028 1
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0048 0.0035 0.0126
Echinococcus multilocularis tubulin epsilon chain 0.005 0.0038 0.0136
Onchocerca volvulus 0.009 0.0085 0.1726
Leishmania major trypanothione reductase 0.0038 0.0024 0.0366
Echinococcus multilocularis Tubulin alpha 1 chain 0.0059 0.0049 0.0172
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0031 0.0016 0.0015
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0025 0.0009 0.0032
Echinococcus granulosus 7TM GPCR rhodopsin 0.009 0.0085 0.0303
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0009 0.004
Loa Loa (eye worm) hypothetical protein 0.0185 0.0199 0.0521
Echinococcus multilocularis g protein coupled receptor 0.009 0.0085 0.0303
Trichomonas vaginalis set domain proteins, putative 0.0236 0.0259 0.9243
Loa Loa (eye worm) GABA receptor subunit 0.0056 0.0045 0.0118
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0024 0.0366
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0013 0.044
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Schistosoma mansoni opsin-like receptor 0.009 0.0085 0.0382
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0065 0.0231
Brugia malayi Cathepsin L-like precursor 0.0019 0.0001 0.0003
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0009 0.004
Schistosoma mansoni hypothetical protein 0.0524 0.06 0.2682
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0066 0.1016
Toxoplasma gondii alpha-tubulin I, putative 0.0059 0.0049 0.1944
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0076 0.034
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0023 0.0007 0.0481
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0036 0.0022 0.0078
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Plasmodium vivax SET domain protein, putative 0.003 0.0015 0.1335
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0563 0.0647 0.2294
Leishmania major p450 reductase, putative 0.0027 0.0011 0.017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.0414 0.047 0.1231
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0023 0.0007 0.0023
Brugia malayi Cation transporter family protein 0.0103 0.0101 0.0266
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0027 0.0011 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0086 0.0384
Schistosoma mansoni nAChR subunit 0.0103 0.0101 0.0453
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Giardia lamblia Gamma tubulin 0.005 0.0038 0.3329
Echinococcus multilocularis nAChR subunit 0.0103 0.0101 0.0359
Plasmodium falciparum phosphodiesterase delta, putative 0.0023 0.0007 0.0589
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0103 0.0101 0.0266
Loa Loa (eye worm) tubulin beta chain 0.0022 0.0005 0.0013
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0013 0.1088
Brugia malayi Tubulin beta chain 0.0028 0.0013 0.0033
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Echinococcus granulosus neuropeptide receptor 0.009 0.0085 0.0303
Schistosoma mansoni heat shock protein 0.0031 0.0016 0.0073
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0001 0.0097
Giardia lamblia Beta tubulin 0.0112 0.0112 1
Schistosoma mansoni integrin beta subunit 0.1904 0.2237 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Brugia malayi Tubulin gamma chain 0.005 0.0038 0.01
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0013 0.708
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0031 0.0016 0.0544
Brugia malayi hypothetical protein 0.0048 0.0035 0.0093
Trypanosoma brucei alpha tubulin 0.0059 0.0049 0.075
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0103 0.0101 0.0359
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0083 0.0077 0.0274
Loa Loa (eye worm) BEN-1 protein 0.0112 0.0112 0.0295
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0041 0.0028 0.0028
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0036 0.0022 0.0078
Trichomonas vaginalis tubulin beta chain, putative 0.0059 0.0049 0.1701
Echinococcus granulosus peroxisome assembly protein 26 0.0059 0.0049 0.0172
Onchocerca volvulus 0.003 0.0015 0.0284
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0024
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0032 0.0016 0.0043
Echinococcus multilocularis FTZ F1 alpha 0.0036 0.0022 0.0078
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0048 0.0035 0.0126
Onchocerca volvulus 0.009 0.0085 0.1726
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0023 0.0007 0.0102
Echinococcus multilocularis Tubulin alpha 1 chain 0.0059 0.0049 0.0172
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0023 0.0007 0.0023
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0025 0.0089
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Echinococcus granulosus neuropeptides capa receptor 0.009 0.0085 0.0303
Onchocerca volvulus 0.0048 0.0035 0.0703
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0023 0.0007 0.003
Trypanosoma brucei epsilon tubulin 0.005 0.0038 0.0592
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0041 0.0028 0.0028
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0023 0.0007 0.0023
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.0456 0.1616
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0031 0.0016 0.0544
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0589
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0041 0.0028 0.0028
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0056 0.0045 0.0118
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0031 0.0016 0.031
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0023 0.0007 0.0017
Loa Loa (eye worm) tubulin alpha 2 0.0037 0.0023 0.006
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0013 0.1189
Onchocerca volvulus 0.0103 0.0101 0.2049
Echinococcus multilocularis somatostatin receptor 0.009 0.0085 0.0303
Loa Loa (eye worm) hypothetical protein 0.0491 0.0562 0.1473
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0041 0.0028 0.0028
Loa Loa (eye worm) abnormal epIthelia family member 0.0023 0.0007 0.0018
Trichomonas vaginalis tubulin gamma chain, putative 0.005 0.0038 0.1333
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0106 0.0376
Loa Loa (eye worm) hypothetical protein 0.0431 0.049 0.1285
Loa Loa (eye worm) hypothetical protein 0.0042 0.0028 0.0075
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0106 0.3758
Loa Loa (eye worm) hypothetical protein 0.0362 0.0409 0.1071
Echinococcus granulosus tubulin beta 4A class IVa 0.0112 0.0112 0.0399
Plasmodium falciparum amino acid transporter, putative 0.0025 0.0009 0.0804
Brugia malayi hypothetical protein 0.0048 0.0035 0.0093
Plasmodium vivax tubulin gamma chain, putative 0.005 0.0038 0.3404
Onchocerca volvulus 0.0103 0.0101 0.2049
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.0016 0.0251
Brugia malayi neuropeptide F receptor 0.009 0.0085 0.0224
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0083 0.0077 0.0274
Trichomonas vaginalis sensor histidine kinase, putative 0.0031 0.0016 0.0544
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0036 0.0022 0.0078
Schistosoma mansoni tubulin subunit gamma 0.005 0.0038 0.0171
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0003
Brugia malayi Cathepsin L-like precursor 0.0019 0.0001 0.0003
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0103 0.0101 0.0453
Schistosoma mansoni histamine h1 receptor 0.009 0.0085 0.0382
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0101 0.0266
Echinococcus granulosus Tubulin beta 2C chain 0.0112 0.0112 0.0399
Schistosoma mansoni rhodopsin-like orphan GPCR 0.009 0.0085 0.0382
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.0066 1
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0061 0.0947
Loa Loa (eye worm) serotonin transporter b 0.0149 0.0155 0.0407
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0112 0.0112 0.0399
Leishmania major cytochrome p450-like protein 0.0069 0.0061 0.0947
Brugia malayi nuclear hormone receptor 0.0036 0.0022 0.0058
Trypanosoma brucei heat shock protein, putative 0.0031 0.0016 0.0251
Schistosoma mansoni nAChR subunit 0.0103 0.0101 0.0453
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0001 0.002
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0034 0.0089
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0065 0.0057 0.0052
Loa Loa (eye worm) hypothetical protein 0.0091 0.0087 0.0227
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0031 0.0016 1
Plasmodium vivax tubulin alpha chain, putative 0.0059 0.0049 0.4315
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0009 0.004
Schistosoma mansoni adenoreceptor 0.009 0.0085 0.0382
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0041 0.0028 0.0435
Echinococcus multilocularis nAChR subunit 0.0056 0.0045 0.0159
Plasmodium falciparum endoplasmin, putative 0.0031 0.0016 0.1446
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Chlamydia trachomatis DNA gyrase subunit B 0.0031 0.0016 1
Brugia malayi Cytochrome P450 family protein 0.0069 0.0061 0.0161
Loa Loa (eye worm) neuropeptide F receptor 0.009 0.0085 0.0224
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Echinococcus granulosus tm gpcr rhodopsin 0.009 0.0085 0.0303
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0041 0.0028 0.0028
Echinococcus multilocularis neuropeptide Y receptor 0.009 0.0085 0.0303
Giardia lamblia High cysteine protein 0.0104 0.0103 0.9124
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0177 0.629
Mycobacterium tuberculosis Probable two component sensor kinase 0.0031 0.0016 0.0016
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0013 0.1189
Echinococcus multilocularis RUN 0.0039 0.0025 0.0089
Brugia malayi Cyclic-nucleotide gated cation channel 0.0025 0.0009 0.0022
Loa Loa (eye worm) tubulin alpha-2 chain 0.0059 0.0049 0.0127
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0024 0.2105
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0024 0.0024
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.005 0.0772
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0048 0.0035 0.0126
Schistosoma mansoni acetylcholine receptor subunit beta 0.0048 0.0035 0.0159
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0031 0.0016 0.0015
Echinococcus multilocularis G-protein coupled receptor, putative 0.009 0.0085 0.0303
Schistosoma mansoni coup transcription factor 0.0036 0.0022 0.0099
Echinococcus multilocularis lamin dm0 0.0086 0.0081 0.0289
Onchocerca volvulus 0.009 0.0085 0.1726
Schistosoma mansoni amine GPCR 0.009 0.0085 0.0382
Echinococcus granulosus glycine receptor subunit beta 0.0103 0.0101 0.0359
Echinococcus granulosus biogenic amine 5HT receptor 0.009 0.0085 0.0303
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0016 0.0057
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0023 0.0007 0.003
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0025 0.0009 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0022 0.0058
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0009 0.004
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0103 0.0101 0.0359
Echinococcus granulosus rhodopsin orphan GPCR 0.009 0.0085 0.0303
Trypanosoma cruzi epsilon tubulin, putative 0.005 0.0038 0.0592
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0103 0.0101 0.0453
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0018
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0041 0.0028 0.0028
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0027 0.0011 0.0039
Schistosoma mansoni rab6-interacting 0.0039 0.0025 0.0112
Echinococcus multilocularis biogenic amine (5HT) receptor 0.009 0.0085 0.0303
Schistosoma mansoni alpha tubulin 0.0059 0.0049 0.0217
Schistosoma mansoni amine GPCR 0.009 0.0085 0.0382
Echinococcus granulosus poly (ADP ribose) polymerase 0.002 0.0002 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0036 0.0022 0.0058
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0041 0.0028 0.0435
Loa Loa (eye worm) hypothetical protein 0.0056 0.0045 0.0118
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0023 0.0007 0.0023
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0025 0.0009 0.003
Echinococcus granulosus Tubulin alpha 1 chain 0.0059 0.0049 0.0172
Leishmania major epsilon tubulin, putative 0.005 0.0038 0.0592
Schistosoma mansoni cytochrome P450 reductase 0.0027 0.0011 0.0049
Plasmodium falciparum tubulin gamma chain 0.005 0.0038 0.3404
Loa Loa (eye worm) hypothetical protein 0.0149 0.0155 0.0407
Schistosoma mansoni tubulin subunit alpha 0.0059 0.0049 0.0217
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0016 0.0057
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0019 0.0002 0.0006
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0025 0.0066
Onchocerca volvulus 0.009 0.0085 0.1726
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0009 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0036 0.0022 0.0058
Plasmodium falciparum tubulin epsilon chain, putative 0.005 0.0038 0.3404
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0061 0.0161
Onchocerca volvulus 0.0056 0.0045 0.0896
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0036 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Echinococcus multilocularis rhodopsin orphan GPCR 0.009 0.0085 0.0303
Schistosoma mansoni biogenic amine (5HT) receptor 0.009 0.0085 0.0382
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0016 0.0042
Mycobacterium tuberculosis Probable reductase 0.0086 0.0081 0.0081
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.009 0.0085 0.0382
Brugia malayi hypothetical protein 0.0491 0.0562 0.1473
Loa Loa (eye worm) hypothetical protein 0.0563 0.0647 0.1696
Schistosoma mansoni nAChR subunit 0.0103 0.0101 0.0453
Echinococcus granulosus heat shock protein 0.0031 0.0016 0.0058
Echinococcus granulosus glycine receptor subunit beta 0.0103 0.0101 0.0359
Echinococcus granulosus tubulin epsilon chain 0.005 0.0038 0.0136
Loa Loa (eye worm) hypothetical protein 0.0149 0.0155 0.0407
Loa Loa (eye worm) intermediate filament protein 0.0086 0.0081 0.0213
Echinococcus multilocularis lamin 0.0086 0.0081 0.0289
Schistosoma mansoni hypothetical protein 0.009 0.0085 0.0382
Schistosoma mansoni tubulin subunit beta 0.0112 0.0112 0.0503
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0036 0.0022 0.0099
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0025 0.0009 0.0032
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0198
Loa Loa (eye worm) CYP4Cod1 0.0069 0.0061 0.0161
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Leishmania major developmentally regulated phosphoprotein-like protein 0.0563 0.0647 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0112 0.0112 0.3993
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0016 0.0042
Brugia malayi EGF-like domain containing protein 0.0104 0.0103 0.0269
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0031 0.0016 0.0251
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0001 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0015 0.0067
Onchocerca volvulus Bile acid receptor homolog 0.0036 0.0022 0.0429
Trypanosoma brucei heat shock protein, putative 0.0031 0.0016 0.0251
Schistosoma mansoni hypothetical protein 0.0039 0.0025 0.0112
Onchocerca volvulus 0.0039 0.0025 0.0492
Trypanosoma brucei cytochrome P450, putative 0.0069 0.0061 0.0947
Loa Loa (eye worm) tubulin beta-2A chain 0.0112 0.0112 0.0295
Loa Loa (eye worm) tubulin alpha-3 chain 0.003 0.0015 0.0039
Echinococcus granulosus fibrillin 2 0.0104 0.0103 0.0364
Echinococcus multilocularis voltage gated potassium channel 0.0032 0.0016 0.0058
Echinococcus granulosus somatostatin receptor 0.009 0.0085 0.0303
Schistosoma mansoni poly [ADP-ribose] polymerase 0.007 0.0062 0.0275
Onchocerca volvulus 0.0025 0.0009 0.0162
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0081 0.0081
Giardia lamblia Alpha-tubulin 0.0059 0.0049 0.4251
Trypanosoma brucei C-8 sterol isomerase, putative 0.0362 0.0409 0.6317
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0024 0.0086
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0031 0.0016 0.0015
Entamoeba histolytica tubulin alpha chain, putative 0.0059 0.0049 0.3701
Echinococcus granulosus hypothetical protein 0.0768 0.089 0.3157
Loa Loa (eye worm) BEN-1 protein 0.0112 0.0112 0.0295
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Trypanosoma brucei alpha tubulin 0.0059 0.0049 0.075
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0031 0.0016 0.0651
Schistosoma mansoni poly [ADP-ribose] polymerase 0.006 0.005 0.0226
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0017
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0096 0.0251
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0007 0.0102
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0025 0.0009 0.0032
Echinococcus multilocularis tubulin delta chain 0.0022 0.0005 0.0017
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0001 0.0097
Schistosoma mansoni peptide (allatostatin)-like receptor 0.009 0.0085 0.0382
Echinococcus granulosus neuropeptides capa receptor 0.009 0.0085 0.0303
Schistosoma mansoni tubulin subunit alpha 0.0059 0.0049 0.0217
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Schistosoma mansoni neuropeptide receptor 0.009 0.0085 0.0382
Leishmania major cathepsin L-like protease 0.0019 0.0001 0.0017
Schistosoma mansoni neuropeptide receptor 0.009 0.0085 0.0382
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Brugia malayi WGR domain containing protein 0.0127 0.0129 0.0339
Schistosoma mansoni biogenic amine receptor 0.009 0.0085 0.0382
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0001 0.0003
Plasmodium vivax DNA gyrase subunit B, putative 0.0031 0.0016 0.1446
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0106 0.0106
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Toxoplasma gondii exonuclease III APE 0.0019 0.0001 0.0051
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0267 0.0296 0.0777
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0016 0.1446
Schistosoma mansoni slit 0.0023 0.0007 0.0031
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0027 0.0011 0.017
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Onchocerca volvulus Phospholipase A2 homolog 0.0431 0.049 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0023 0.0007 0.003
Brugia malayi nuclear receptor NHR-88 0.0036 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Treponema pallidum cell division protein FtsZ 0.0022 0.0005 0.0229
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0061 0.0947
Trypanosoma brucei trypanothione reductase 0.0038 0.0024 0.0366
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0028 0.0013 0.0412
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0041 0.0028 0.0027
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0025 0.0009 0.003
Trichomonas vaginalis receptor histidine kinase, putative 0.0031 0.0016 0.0544
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0018
Echinococcus multilocularis tubulin alpha 1C chain 0.0059 0.0049 0.0172
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0048 0.0035 0.0093
Trichomonas vaginalis tubulin beta chain, putative 0.0028 0.0013 0.0412
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0023 0.0007 0.0031
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0025 0.0009 0.0038
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0024 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.009 0.0085 0.0303
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0031 0.0016 0.0058
Mycobacterium tuberculosis Probable histidinol dehydrogenase HisD (HDH) 0.8452 1 1
Schistosoma mansoni cpg binding protein 0.003 0.0014 0.0065
Loa Loa (eye worm) heat shock protein 90 0.0031 0.0016 0.0043
Giardia lamblia Tenascin-37 0.0104 0.0103 0.9124
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Onchocerca volvulus 0.009 0.0085 0.1726
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0589
Echinococcus multilocularis tubulin alpha chain 0.0059 0.0049 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Mycobacterium leprae putative cytochrome p450 0.0041 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.006
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0006 0.0098
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0065 0.0231
Giardia lamblia Hypothetical protein 0.0024 0.0007 0.055
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0023 0.0007 0.0023
Echinococcus multilocularis hyperpolarization activated cyclic 0.0025 0.0009 0.003
Schistosoma mansoni biogenic amine receptor 0.009 0.0085 0.0382
Onchocerca volvulus 0.0086 0.0081 0.1642
Schistosoma mansoni retinoic acid receptor RXR 0.0036 0.0022 0.0099
Giardia lamblia Tenascin-like 0.0104 0.0103 0.9124
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0127 0.0129 0.0578
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Echinococcus granulosus ecdysone induced protein 78C 0.0036 0.0022 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0041 0.0028 0.0028
Schistosoma mansoni neurotransmitter gated ion channel 0.0048 0.0035 0.0159
Echinococcus multilocularis beta tubulin 0.0112 0.0112 0.0399
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0031 0.0016 0.0016
Schistosoma mansoni intermediate filament proteins 0.0086 0.0081 0.0364
Onchocerca volvulus 0.0082 0.0076 0.1531
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Onchocerca volvulus 0.009 0.0085 0.1726
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.007 0.0062 0.0952
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0002 0.0005
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0589
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0036 0.0022 0.0058
Brugia malayi hypothetical protein 0.0025 0.0009 0.0024
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0048 0.0035 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0007 0.0198
Schistosoma mansoni neuropeptide receptor 0.009 0.0085 0.0382
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0103 0.0101 0.0266
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0002 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0036 0.0022 0.0099
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Echinococcus granulosus rhodopsin orphan GPCR 0.009 0.0085 0.0303
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0177 0.629
Plasmodium vivax flavodoxin domain containing protein 0.0024 0.0007 0.0657
Echinococcus multilocularis rhodopsin orphan GPCR 0.009 0.0085 0.0303
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0048 0.0035 0.0126
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0036 0.0022 0.0429
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0083 0.0078 0.0204
Loa Loa (eye worm) hypothetical protein 0.0209 0.0228 0.0597
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0036 0.0022 0.0058
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0016 0.0544
Loa Loa (eye worm) hypothetical protein 0.0085 0.008 0.0208
Schistosoma mansoni pyruvate dehydrogenase 0.0532 0.061 0.2725
Brugia malayi tubulin alpha chain - mouse 0.0059 0.0049 0.0127
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0103 0.0101 0.0453
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0103 0.0101 0.0359
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0031 0.0016 0.0544
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0027 0.0011 0.017
Schistosoma mansoni myosin xvIII 0.009 0.0085 0.0382
Brugia malayi Serotonin receptor 0.009 0.0085 0.0224
Echinococcus granulosus tubulin delta chain 0.0022 0.0005 0.0017
Leishmania major cytochrome p450-like protein 0.0041 0.0028 0.0435
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0066 0.2317
Trypanosoma cruzi zeta tubulin, putative 0.0022 0.0005 0.0074
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0083 0.0078 0.0276
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Loa Loa (eye worm) ctsf protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0039
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0041 0.0028 0.0027
Echinococcus granulosus pikachurin 0.0023 0.0007 0.0024
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0106 0.1637
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Leishmania major cathepsin L-like protease 0.0071 0.0063 0.0972
Loa Loa (eye worm) solute carrier family 6 member 4 0.0149 0.0155 0.0407
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0006 0.0565
Giardia lamblia Beta tubulin 0.0112 0.0112 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Schistosoma mansoni nAChR subunit 0.0048 0.0035 0.0159
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0069 0.0061 0.006
Echinococcus multilocularis tubulin alpha 0.005 0.0038 0.0136
Schistosoma mansoni hypothetical protein 0.0031 0.0016 0.0072
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0025 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0024
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0589
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0001 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.009 0.0085 0.0382
Echinococcus multilocularis tubulin gamma 1 chain 0.005 0.0038 0.0136
Echinococcus granulosus p2X purinoceptor 4 0.0077 0.0071 0.0252
Brugia malayi EGF-like domain containing protein 0.0104 0.0103 0.0269
Brugia malayi Steroid receptor seven-up type 2 0.0036 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Brugia malayi Serotonin receptor 0.0542 0.0622 0.1631
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0031 0.0016 0.0016
Leishmania major cathepsin L-like protease 0.0071 0.0063 0.0972
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0103 0.0101 0.0359
Trichomonas vaginalis tubulin epsilon chain, putative 0.0022 0.0005 0.0133
Brugia malayi EGF-like domain containing protein 0.0104 0.0103 0.0269
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0225 0.059
Echinococcus granulosus orexin receptor type 2 0.009 0.0085 0.0303
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0197 0.0213 0.3286
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Loa Loa (eye worm) FAD binding domain-containing protein 0.0027 0.0011 0.0029
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0103 0.0101 0.0266
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0016 0.0057
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0023 0.0007 0.0023
Echinococcus granulosus alpha tubulin 0.0059 0.0049 0.0172
Entamoeba histolytica hypothetical protein 0.0083 0.0077 0.5934
Brugia malayi RE15519p 0.009 0.0085 0.0224
Onchocerca volvulus Putative nachr subunit 0.0103 0.0101 0.2049
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0031 0.0016 0.0973
Schistosoma mansoni hypothetical protein 0.009 0.0085 0.0382
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.0066 0.0064
Schistosoma mansoni 60S ribosomal protein L21 0.0022 0.0005 0.0023
Brugia malayi Dopamine receptor protein 1 0.009 0.0085 0.0224
Echinococcus multilocularis tubulin alpha chain 0.0059 0.0049 0.0172
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0009 0.004
Echinococcus granulosus GPCR family 2 0.0031 0.0016 0.0057
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0001 0.002
Echinococcus multilocularis p2X purinoceptor 4 0.0077 0.0071 0.0252
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Brugia malayi alpha-tubulin 0.0059 0.0049 0.0127
Brugia malayi Inositol-1 0.0073 0.0066 0.0172
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0001 0.0004
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0056 0.0045 0.0118
Schistosoma mansoni lamin 0.0086 0.0081 0.0364
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0106 0.0473
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Loa Loa (eye worm) hypothetical protein 0.0032 0.0016 0.0043
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0001 0.0003
Echinococcus granulosus neuropeptide Y receptor 0.009 0.0085 0.0303
Echinococcus granulosus rhodopsin orphan GPCR 0.009 0.0085 0.0303
Loa Loa (eye worm) hypothetical protein 0.0104 0.0103 0.0269
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0149 0.0155 0.0694
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0001 0.0004
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0023 0.0007 0.0102
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0041 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0024
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Schistosoma mansoni inositol monophosphatase 0.0073 0.0066 0.0294
Trypanosoma brucei epsilon tubulin 0.005 0.0038 0.0592
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0022 0.0058
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0036 0.0022 0.0078
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0041 0.0028 0.0027
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0013 0.0535
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0009 0.0038
Schistosoma mansoni tubulin subunit delta 0.0022 0.0005 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.028 1
Echinococcus granulosus RUN 0.0039 0.0025 0.0089
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0103 0.0101 0.0453
Schistosoma mansoni nAChR subunit 0.0103 0.0101 0.0453
Schistosoma mansoni hypothetical protein 0.0041 0.0028 0.0126
Trichomonas vaginalis tubulin, putative 0.0028 0.0013 0.0412
Brugia malayi Phospholipase A2 family protein 0.0091 0.0087 0.0227
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Schistosoma mansoni sodium-dependent amino acid transporter 0.0025 0.0009 0.004
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0232 0.0255 0.0903
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0023 0.0007 0.0102
Loa Loa (eye worm) hypothetical protein 0.0497 0.0568 0.149
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0036 0.0022 0.0058
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0009 0.0032
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Loa Loa (eye worm) tubulin beta-4 chain 0.0112 0.0112 0.0295
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0045 0.0695
Schistosoma mansoni neuropeptide receptor 0.009 0.0085 0.0382
Brugia malayi Tubulin alpha-2 chain 0.0059 0.0049 0.0127
Schistosoma mansoni loxhd1 0.0039 0.0025 0.0112
Schistosoma mansoni P2X receptor subunit 0.0077 0.0071 0.0317
Loa Loa (eye worm) norepinephrine transporter 0.0149 0.0155 0.0407
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Trichomonas vaginalis tubulin epsilon chain, putative 0.0112 0.0112 0.3993
Loa Loa (eye worm) hypothetical protein 0.0209 0.0228 0.0597
Leishmania major cathepsin L-like protease 0.0019 0.0001 0.0017
Mycobacterium tuberculosis Possible two component sensor kinase 0.0031 0.0016 0.0016
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0001 0.0005
Schistosoma mansoni nAChR subunit 0.0103 0.0101 0.0453
Echinococcus multilocularis rhodopsin orphan GPCR 0.009 0.0085 0.0303
Entamoeba histolytica hypothetical protein 0.002 0.0002 0.0104
Brugia malayi Doublecortin family protein 0.0039 0.0025 0.0066
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0022 0.0099
Loa Loa (eye worm) melatonin receptor type 1A 0.009 0.0085 0.0224
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0013 0.0785
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.0042
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Echinococcus granulosus neuropeptide receptor 0.009 0.0085 0.0303
Schistosoma mansoni rhodopsin-like orphan GPCR 0.009 0.0085 0.0382
Echinococcus granulosus cytochrome P450 2K1 0.0041 0.0028 0.01
Echinococcus multilocularis fibrillin 2 0.0104 0.0103 0.0364
Plasmodium falciparum thioredoxin reductase 0.0038 0.0024 0.2105
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0589
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0103 0.0101 0.0359
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0025 0.0009 0.003
Leishmania major cytochrome P450 reductase, putative 0.0024 0.0007 0.0114
Mycobacterium ulcerans two component regulator - sensor kinase 0.0031 0.0016 0.0015
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0103 0.0101 0.0266
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Loa Loa (eye worm) hypothetical protein 0.0056 0.0045 0.0118
Echinococcus multilocularis musashi 0.0086 0.0081 0.0289
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0066 0.1016
Echinococcus granulosus WGR domain containing protein 0.0039 0.0026 0.0091
Onchocerca volvulus 0.0048 0.0035 0.0703
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0068 0.006 0.2109
Toxoplasma gondii hypothetical protein 0.0025 0.0009 0.0362
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0006 0.0255
Toxoplasma gondii heat shock protein HSP90 0.0031 0.0016 0.0651
Echinococcus granulosus tubulin alpha 1C chain 0.0059 0.0049 0.0172
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Echinococcus multilocularis heat shock protein 90 0.0031 0.0016 0.0058
Echinococcus multilocularis integrin beta 2 0.2396 0.282 1
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0031 0.0016 0.2326
Trypanosoma brucei heat shock protein, putative 0.0031 0.0016 0.0251
Loa Loa (eye worm) hypothetical protein 0.0025 0.0009 0.0024
Echinococcus multilocularis neurogenic locus notch protein 0.0023 0.0007 0.0024
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0106 0.6789
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0061 0.0161
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.009 0.0085 0.0303
Trichomonas vaginalis tubulin epsilon chain, putative 0.0112 0.0112 0.3993
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.009 0.0085 0.0382
Giardia lamblia Nitric oxide synthase, inducible 0.0024 0.0007 0.055
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0009 0.0032
Echinococcus multilocularis fibrillin 1 0.0104 0.0103 0.0364
Schistosoma mansoni hypothetical protein 0.009 0.0085 0.0382
Giardia lamblia Neurogenic locus Notch protein precursor 0.0104 0.0103 0.9124
Echinococcus multilocularis neuropeptide receptor 0.009 0.0085 0.0303
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0023 0.0007 0.0102
Echinococcus granulosus serotonin receptor 0.009 0.0085 0.0303
Echinococcus granulosus tachykinin peptides receptor 99D 0.009 0.0085 0.0303
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0009 0.0362
Brugia malayi laminin alpha chain 0.0023 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Echinococcus multilocularis g protein coupled receptor 0.009 0.0085 0.0303
Loa Loa (eye worm) hypothetical protein 0.0056 0.0045 0.0118
Toxoplasma gondii beta tubulin 0.0112 0.0112 0.4504
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0433 0.0493 0.0492
Brugia malayi glutathione reductase 0.0038 0.0024 0.0062
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Echinococcus multilocularis allatostatin A receptor 0.009 0.0085 0.0303
Schistosoma mansoni rab6-interacting 0.0039 0.0025 0.0112
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0041 0.0028 0.0027
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0041 0.0028 0.0027
Trichomonas vaginalis tubulin, putative 0.0022 0.0005 0.0133
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0023 0.0007 0.003
Echinococcus multilocularis slit 2 protein 0.0023 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0056 0.0045 0.0118
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0006 0.0005
Schistosoma mansoni endoplasmin 0.0031 0.0016 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.009 0.0085 0.0382
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0025 0.0009 0.2707
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0023 0.0007 0.0017
Echinococcus multilocularis neuropeptides capa receptor 0.009 0.0085 0.0303
Brugia malayi FAD binding domain containing protein 0.0027 0.0011 0.0029
Echinococcus granulosus poly (ADP ribose) polymerase 0.0039 0.0026 0.0091
Trichomonas vaginalis tubulin epsilon chain, putative 0.0059 0.0049 0.1701
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0019 0.0002 0.0008
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0027 0.0011 0.001
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0022 0.0005 0.0192
Brugia malayi gonadotropin-releasing hormone receptor 2 0.009 0.0085 0.0224
Mycobacterium ulcerans histidinol dehydrogenase 0.8452 1 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0001 0.0004
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0103 0.0101 0.0266
Echinococcus granulosus hyperpolarization activated cyclic 0.0025 0.0009 0.003
Echinococcus multilocularis fmrfamide receptor 0.009 0.0085 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0022 0.0058
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0022 0.0078
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.009 0.0085 0.0303
Loa Loa (eye worm) cytochrome P450 0.0041 0.0028 0.0074
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0106 0.0473
Brugia malayi larval opioid receptor 0.009 0.0085 0.0224
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0103 0.0101 0.0266
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0023 0.0007 0.0023
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0009 0.004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0005
Echinococcus multilocularis serotonin receptor 0.0209 0.0228 0.0807
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0101 0.0266
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0041 0.0028 0.0028
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0076 0.0269
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0015 0.0053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.009 0.0085 0.0303
Schistosoma mansoni acetylcholine receptor-related 0.0048 0.0035 0.0159
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0029
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0086 0.0081 0.0213
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0362 0.0409 0.6317
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0001 0.0014
Loa Loa (eye worm) TYRA-2 protein 0.009 0.0085 0.0224
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0009 0.0032
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Echinococcus multilocularis cysteine protease 0.0019 0.0001 0.0004
Giardia lamblia Tenascin precursor 0.0104 0.0103 0.9124
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0177 0.629
Loa Loa (eye worm) hypothetical protein 0.0854 0.0991 0.2599
Echinococcus multilocularis cpg binding protein 0.003 0.0014 0.0051
Trypanosoma cruzi tubulin delta chain 0.0022 0.0005 0.0074
Echinococcus multilocularis neuropeptides capa receptor 0.009 0.0085 0.0303
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0005
Leishmania major alpha tubulin 0.0059 0.0049 0.075
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Brugia malayi Plexin repeat family protein 0.002 0.0003 0.0008
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0563 0.0647 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0041 0.0028 0.0027
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.028 0.0734
Brugia malayi Pre-SET motif family protein 0.0207 0.0225 0.059
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0103 0.0101 0.0359
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Brugia malayi plexin A 0.0024 0.0007 0.0019
Schistosoma mansoni hypothetical protein 0.0524 0.06 0.2682
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0023 0.0007 0.0023
Brugia malayi G-protein coupled receptor 0.009 0.0085 0.0224
Schistosoma mansoni lamin 0.0086 0.0081 0.0364
Brugia malayi hypothetical protein 0.0048 0.0035 0.0093
Onchocerca volvulus 0.0028 0.0013 0.0235
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.0016 0.0251
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.0266
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0103 0.0101 0.0359
Schistosoma mansoni ap endonuclease 0.0019 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.004 0.0027 0.007
Loa Loa (eye worm) hypothetical protein 0.0098 0.0096 0.0251
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0031 0.0016 0.0016
Plasmodium vivax tubulin beta chain, putative 0.0112 0.0112 1
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0023 0.0007 0.0102
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0023 0.0007 0.0102
Chlamydia trachomatis DNA gyrase subunit B 0.0031 0.0016 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0044 0.1754
Echinococcus granulosus hyperpolarization activated cyclic 0.0025 0.0009 0.003
Echinococcus granulosus tubulin subunit beta 0.0112 0.0112 0.0399
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0022 0.0005 0.0133
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0041 0.0028 0.0028
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0059 0.0155
Giardia lamblia hypothetical protein 0.0104 0.0103 0.9124
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Brugia malayi Tubulin beta chain 0.0022 0.0005 0.0013
Loa Loa (eye worm) tubulin alpha chain 0.0059 0.0049 0.0127
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0031 0.0016 0.0251
Schistosoma mansoni hypothetical protein 0.0083 0.0077 0.0345
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0001 0.0003
Loa Loa (eye worm) inositol-1 0.0073 0.0066 0.0172
Giardia lamblia Pms1-like protein 0.0031 0.0016 0.1348
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Loa Loa (eye worm) hypothetical protein 0.0059 0.0049 0.0127
Loa Loa (eye worm) fibroinase 0.0019 0.0001 0.0003
Echinococcus granulosus alpha 1A adrenergic receptor 0.009 0.0085 0.0303
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0027 0.0011 0.017
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0023 0.0007 0.0198
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Echinococcus multilocularis orexin receptor type 2 0.009 0.0085 0.0303
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Echinococcus multilocularis conserved hypothetical protein 0.0679 0.0784 0.278
Echinococcus multilocularis serotonin transporter 0.0149 0.0155 0.0551
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0025 0.2238
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0081 0.0076
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0056 0.0859
Schistosoma mansoni ap endonuclease 0.0019 0.0001 0.0006
Echinococcus granulosus nAChR subunit 0.0103 0.0101 0.0359
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0023 0.0007 0.0198
Echinococcus granulosus poly ADP ribose polymerase 1 0.0127 0.0129 0.0458
Brugia malayi hypothetical protein 0.0048 0.0035 0.0093
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Schistosoma mansoni hypothetical protein 0.0031 0.0016 0.0072
Brugia malayi G protein-coupled receptor 0.009 0.0085 0.0224
Loa Loa (eye worm) hypothetical protein 0.022 0.024 0.0629
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0013 0.0958
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0036 0.0022 0.0058
Echinococcus granulosus tubulin alpha chain 0.0059 0.0049 0.0172
Schistosoma mansoni tubulin subunit beta 0.0112 0.0112 0.0503
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0001 0.0001
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0563 0.0647 0.2294
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0025 0.0009 0.0024
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.005 0.2
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0028 0.0101
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0005
Onchocerca volvulus 0.009 0.0085 0.1726
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0197 0.0213 0.8512
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0041 0.0028 0.0028
Schistosoma mansoni amine GPCR 0.009 0.0085 0.0382
Brugia malayi intermediate filament protein 0.0086 0.0081 0.0213
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0058
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0031 0.0016 0.0015
Loa Loa (eye worm) neuropeptide F receptor 0.009 0.0085 0.0224
Echinococcus granulosus neuropeptide receptor A26 0.009 0.0085 0.0303
Echinococcus multilocularis ecdysone induced protein 78C 0.0036 0.0022 0.0078
Echinococcus multilocularis cysteine protease 0.0019 0.0001 0.0004
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0001 0.002
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0103 0.0101 0.0359
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0063 0.0972
Brugia malayi hypothetical protein 0.0048 0.0035 0.0093
Brugia malayi hypothetical protein 0.0039 0.0025 0.0066
Loa Loa (eye worm) hypothetical protein 0.0056 0.0045 0.0118
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0063 0.0972
Echinococcus granulosus serotonin transporter 0.0149 0.0155 0.0551
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.0043
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0027 0.0011 0.017
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.005 0.0223
Echinococcus multilocularis Tubulin beta 2C chain 0.0112 0.0112 0.0399
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0001 0.002
Mycobacterium leprae Probable two-component sensor kinase 0.0031 0.0016 0.0011
Echinococcus multilocularis tubulin alpha 1C chain 0.0059 0.0049 0.0172
Loa Loa (eye worm) plexin A 0.0024 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0104 0.0103 0.0269
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Schistosoma mansoni RAR-like nuclear receptor 0.0036 0.0022 0.0099
Loa Loa (eye worm) hypothetical protein 0.0067 0.0059 0.0155
Echinococcus granulosus plexin a4 0.0024 0.0007 0.0026
Echinococcus multilocularis serotonin receptor 0.0209 0.0228 0.0807
Echinococcus multilocularis alpha 1A adrenergic receptor 0.009 0.0085 0.0303
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.028 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0015 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0063 0.0972
Schistosoma mansoni steroid hormone receptor ad4bp 0.0036 0.0022 0.0099
Echinococcus multilocularis hyperpolarization activated cyclic 0.0025 0.0009 0.003
Brugia malayi hypothetical protein 0.0083 0.0077 0.0202
Brugia malayi excitatory GABA receptor EXP-1A 0.0103 0.0101 0.0266
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0103 0.0101 0.0359
Trypanosoma brucei heat shock protein, putative 0.0031 0.0016 0.0251
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0013 0.1189
Echinococcus granulosus tubulin alpha chain 0.0059 0.0049 0.0172
Brugia malayi 6-phosphofructokinase 0.0107 0.0106 0.0278
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0007 0.0265
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0081 0.0081
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.009 0.0085 0.0303
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0106 0.0376
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0025 0.0089
Schistosoma mansoni inositol monophosphatase 0.0073 0.0066 0.0294
Giardia lamblia Alpha-tubulin 0.0059 0.0049 0.4251
Schistosoma mansoni P2X receptor subunit 0.0077 0.0071 0.0317
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0036 0.0022 0.0078
Loa Loa (eye worm) hypothetical protein 0.0149 0.0155 0.0407
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0023 0.0007 0.0198
Entamoeba histolytica tubulin gamma chain 0.005 0.0038 0.2902
Echinococcus multilocularis tubulin alpha chain 0.0059 0.0049 0.0172
Echinococcus granulosus thyrotropin releasing hormone receptor 0.009 0.0085 0.0303
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0023 0.0007 0.0102
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0023 0.0007 0.003
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0076 0.0269
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0015 0.0053
Echinococcus granulosus Tubulin beta 2C chain 0.0112 0.0112 0.0399
Brugia malayi Tachykinin-like peptides receptor 99D 0.009 0.0085 0.0224
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0056 0.0045 0.0201
Trypanosoma cruzi heat shock protein 90, putative 0.0031 0.0016 0.0251
Onchocerca volvulus 0.009 0.0085 0.1726
Brugia malayi hypothetical protein 0.0039 0.0025 0.0066
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.009 0.0085 0.0382
Schistosoma mansoni lipoxygenase 0.0162 0.0172 0.0767
Echinococcus multilocularis glycine receptor subunit beta 0.0103 0.0101 0.0359
Trypanosoma cruzi beta tubulin, putative 0.0112 0.0112 0.1739
Brugia malayi nuclear receptor RXR 0.0019 0.0002 0.0005
Brugia malayi EGF-like domain containing protein 0.0104 0.0103 0.0269
Schistosoma mansoni opsin-like receptor 0.009 0.0085 0.0382
Loa Loa (eye worm) tubulin alpha 2 0.0037 0.0023 0.006
Toxoplasma gondii beta-tubulin, putative 0.0112 0.0112 0.4504
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0005 0.0133
Giardia lamblia Tenascin-X 0.0104 0.0103 0.9124
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0041 0.0028 0.0027
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0041 0.0028 0.0027
Trypanosoma brucei beta tubulin 0.0112 0.0112 0.1739
Brugia malayi Melatonin receptor type 1A 0.009 0.0085 0.0224
Onchocerca volvulus 0.009 0.0085 0.1726
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0031 0.0016 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0036 0.0022 0.0058
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0433 0.0493 0.0493
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0006 0.0006
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0023 0.0007 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0063 0.0972
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0058
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0006 0.0565
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0019 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0017
Onchocerca volvulus 0.0048 0.0035 0.0703
Entamoeba histolytica heat shock protein 90, putative 0.0031 0.0016 0.1183
Entamoeba histolytica hypothetical protein 0.0083 0.0077 0.5934
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0031 0.0016 0.1446
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0023 0.0007 0.0198
Echinococcus granulosus tubulin alpha chain 0.0059 0.0049 0.0172
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.028 1
Loa Loa (eye worm) steroid hormone receptor 0.0036 0.0022 0.0058
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Trypanosoma brucei beta tubulin 0.0112 0.0112 0.1739
Onchocerca volvulus Phospholipase A2 homolog 0.0091 0.0087 0.1751
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.009 0.0085 0.0224
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0031 0.0016 0.0058
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0103 0.0101 0.0266
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0032 0.0016 0.0058
Leishmania major heat shock protein 83-1 0.0031 0.0016 0.0251
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0031 0.0016 0.0544
Echinococcus multilocularis g-protein coupled receptor 0.009 0.0085 0.0303
Echinococcus granulosus Tubulin alpha 1 chain 0.0059 0.0049 0.0172
Onchocerca volvulus 0.009 0.0085 0.1726
Trichomonas vaginalis sulfite reductase, putative 0.0027 0.0011 0.0355
Echinococcus multilocularis G protein coupled receptor 139 0.009 0.0085 0.0303
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0106 0.8178
Echinococcus granulosus beta tubulin 0.0112 0.0112 0.0399
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0106 0.3758
Echinococcus multilocularis beta tubulin 0.0112 0.0112 0.0399
Echinococcus granulosus p2X purinoceptor 4 0.0077 0.0071 0.0252
Leishmania major cathepsin L-like protease 0.0019 0.0001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0025 0.0066
Plasmodium falciparum nitric oxide synthase, putative 0.0027 0.0011 0.0979
Echinococcus granulosus tm gpcr rhodopsin 0.0904 0.1051 0.3728
Onchocerca volvulus 0.0103 0.0101 0.2049
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0007 0.0102
Schistosoma mansoni laminin gamma-3 chain 0.0023 0.0007 0.0031
Brugia malayi Integrin beta pat-3 precursor 0.3234 0.3814 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0013 0.044
Schistosoma mansoni amine GPCR 0.0741 0.0858 0.3836
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0016 0.0057
Trypanosoma brucei developmentally regulated phosphoprotein 0.0563 0.0647 1
Brugia malayi neuropeptide F receptor 0.009 0.0085 0.0224
Brugia malayi hypothetical protein 0.009 0.0085 0.0224
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0023 0.0007 0.0023
Brugia malayi Cation transporter family protein 0.0103 0.0101 0.0266
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0007 0.0102
Schistosoma mansoni endoplasmin 0.0031 0.0016 0.0073
Echinococcus multilocularis peroxisome assembly protein 26 0.0059 0.0049 0.0172
Leishmania major hypothetical protein, conserved 0.0023 0.0007 0.0102
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0031 0.0016 0.0251
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0031 0.0016 0.031
Echinococcus granulosus nAChR subunit 0.0056 0.0045 0.0159
Loa Loa (eye worm) hypothetical protein 0.0048 0.0035 0.0093
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0076 0.0199
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Echinococcus granulosus fibrillin 1 0.0104 0.0103 0.0364
Echinococcus multilocularis sex peptide receptor 0.009 0.0085 0.0303
Mycobacterium tuberculosis Conserved protein 0.0031 0.0016 0.0016
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0031 0.0016 0.0011
Entamoeba histolytica DNA topoisomerase II, putative 0.0031 0.0016 0.1183
Schistosoma mansoni rhodopsin-like orphan GPCR 0.009 0.0085 0.0382
Echinococcus multilocularis tubulin subunit beta 0.0112 0.0112 0.0399
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0023 0.0007 0.0023
Brugia malayi hypothetical protein 0.0019 0.0002 0.0005
Echinococcus multilocularis tubulin alpha 3 chain 0.0059 0.0049 0.0172
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.009 0.0085 0.0303
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0027 0.0011 0.017
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0041 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.007 0.0062 0.0161
Trypanosoma brucei epsilon tubulin 0.005 0.0038 0.0592
Leishmania major beta tubulin 0.0112 0.0112 0.1739
Trypanosoma brucei tubulin delta chain 0.0022 0.0005 0.0074
Trypanosoma brucei DNA topoisomerase ii 0.0031 0.0016 0.0251
Echinococcus multilocularis Tubulin beta 2C chain 0.0112 0.0112 0.0399
Entamoeba histolytica hypothetical protein 0.0023 0.0006 0.0411
Loa Loa (eye worm) PDE1B protein 0.0023 0.0007 0.0017
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0101 0.0266
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0149 0.0155 0.0407
Trypanosoma cruzi DNA topoisomerase II, putative 0.0031 0.0016 0.0251
Echinococcus granulosus poly (ADP ribose) polymerase 0.002 0.0002 0.0009
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0103 0.0101 0.0266
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0023 0.0007 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.009 0.0085 0.0303
Loa Loa (eye worm) endoplasmin 0.0031 0.0016 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.009 0.0085 0.0303
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Trichomonas vaginalis tubulin gamma chain, putative 0.0022 0.0005 0.0133
Brugia malayi beta-tubulin, identical 0.0112 0.0112 0.0295
Toxoplasma gondii hypothetical protein 0.0025 0.0009 0.0362
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.028 0.0734
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0025 0.0986
Schistosoma mansoni alpha tubulin 0.0059 0.0049 0.0217
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0023 0.0007 0.0102
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0031 0.0016 0.0544
Echinococcus multilocularis geminin 0.0524 0.06 0.2128
Schistosoma mansoni nAChR subunit 0.0048 0.0035 0.0159
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0103 0.0101 0.0266
Mycobacterium ulcerans putative regultory protein 0.0031 0.0016 0.0015
Brugia malayi Cytochrome P450 family protein 0.0105 0.0104 0.0272
Echinococcus granulosus g protein coupled receptor 0.009 0.0085 0.0303
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0007 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.009 0.0085 0.0303
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0041 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0224
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0041 0.0028 0.0435
Schistosoma mansoni transcription factor LCR-F1 0.0083 0.0077 0.0345
Schistosoma mansoni cell polarity protein 0.0023 0.0007 0.0031
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0023 0.0007 0.0198
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.005 0.0223
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0037 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.0267 0.0296 0.0777
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0041 0.0028 0.0028

Activities

Activity type Activity value Assay description Source Reference
Ratio (functional) = 0.65 Ratio of GH release stimulated by 300 ug/kg of compound to that of GH release stimulated by 300 ug/kg of hexarelin in infant rat (sc injection) ChEMBL. 12646029

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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