Detailed information for compound 135688

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 661.867 | Formula: C40H55NO7
  • H donors: 1 H acceptors: 4 LogP: 8.18 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCC(C(=O)O[C@@H]1C[C@@H](C)[C@H]([C@H]2C1[C@H](CCC1C[C@@H](O)CC(=O)O1)[C@@H](CC2)C)OC(=O)N(Cc1ccccc1)Cc1ccccc1)(C)C
  • InChi: 1S/C40H55NO7/c1-6-40(4,5)38(44)47-34-21-27(3)37(33-19-17-26(2)32(36(33)34)20-18-31-22-30(42)23-35(43)46-31)48-39(45)41(24-28-13-9-7-10-14-28)25-29-15-11-8-12-16-29/h7-16,26-27,30-34,36-37,42H,6,17-25H2,1-5H3/t26-,27+,30+,31?,32-,33+,34-,36?,37+/m0/s1
  • InChiKey: KDQFSEFEJYDHTG-MJAAVMQXSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Schistosoma mansoni hypothetical protein 0.0057 0.0123 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0074 0.0402
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0108 0.0269 0.0372
Echinococcus multilocularis fat cadherin tumor suppressor 0.0441 0.1225 0.1225
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0108 0.0269 0.0372
Plasmodium vivax multidomain scavenger receptor, putative 0.0139 0.0358 0.3568
Echinococcus granulosus biogenic amine 5HT receptor 0.0057 0.0123 0.0123
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0088 0.048
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Echinococcus granulosus geminin 0.0344 0.0947 0.0947
Echinococcus multilocularis insulin receptor 0.0046 0.0092 0.0092
Schistosoma mansoni slit 0.0441 0.1225 0.1225
Loa Loa (eye worm) neuropeptide F receptor 0.0057 0.0123 0.017
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0085 0.0085
Schistosoma mansoni polycystin 1-related 0.0139 0.0358 0.0358
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0277 0.1383
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0081 0.0081
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0088 0.048
Loa Loa (eye worm) hypothetical protein 0.0035 0.0058 0.008
Schistosoma mansoni nuclear receptor 0.0051 0.0105 0.0105
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0251 0.0251
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0108 0.0269 0.0269
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0108 0.0269 0.0372
Echinococcus multilocularis aldo keto reductase 0.0111 0.0277 0.0277
Schistosoma mansoni notch 0.0441 0.1225 0.1225
Schistosoma mansoni notch 0.0441 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0034 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0059 0.0295
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0034 0.0055 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.005 0.0104 0.0519
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0043 0.0084 0.0455
Onchocerca volvulus 0.0057 0.0123 0.017
Onchocerca volvulus 0.2531 0.7224 1
Loa Loa (eye worm) hypothetical protein 0.0188 0.0498 0.0689
Leishmania major p450 reductase, putative 0.0026 0.0034 0.0183
Echinococcus granulosus fatty acid binding protein FABP2 0.0034 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0174 0.0458 0.0458
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0057 0.0123 0.0123
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.019 0.019
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0654 0.1837 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0057 0.0123 0.017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0104 0.0519
Echinococcus granulosus neural cadherin 0.0441 0.1225 0.1225
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0081 0.0403
Brugia malayi AKH receptor 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0026 0.0034 0.0034
Echinococcus granulosus dna polymerase kappa 0.004 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Echinococcus multilocularis GPCR, family 2 0.008 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0043 0.0083 0.0115
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0108 0.0269 0.0269
Mycobacterium ulcerans glyoxalase GloA 0.0043 0.0084 0.0455
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0277 0.0277
Brugia malayi follicle stimulating hormone receptor 0.0057 0.0123 0.017
Brugia malayi Nuclear hormone receptor E75 0.0051 0.0105 0.0145
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0003 0.0003
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Brugia malayi G-protein coupled receptor 0.0057 0.0123 0.017
Brugia malayi Calcium binding EGF domain containing protein 0.0441 0.1225 0.1696
Leishmania major cysteine peptidase A (CPA) 0.005 0.0104 0.0565
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Schistosoma mansoni cpg binding protein 0.006 0.0131 0.0131
Echinococcus granulosus GPCR family 2 0.008 0.019 0.019
Plasmodium falciparum glyoxalase I 0.0043 0.0084 0.0833
Echinococcus multilocularis thyroid hormone receptor alpha 0.0357 0.0984 0.0984
Brugia malayi dehydrogenases, short chain protein 2 0.0043 0.0083 0.0115
Trichomonas vaginalis histone deacetylase, putative 0.0364 0.1003 0.5018
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0008 0.0039
Trypanosoma cruzi aldo-keto reductase 0.0111 0.0277 0.1505
Schistosoma mansoni hypothetical protein 0.0441 0.1225 0.1225
Schistosoma mansoni ap endonuclease 0.0056 0.012 0.012
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0052 0.0428
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0133 0.0133
Echinococcus granulosus fatty acid binding protein FABP2 0.0034 0.0055 0.0055
Onchocerca volvulus 0.0139 0.0358 0.0495
Schistosoma mansoni hypothetical protein 0.008 0.019 0.019
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0165 0.0433 0.2359
Brugia malayi histone deacetylase 3 (HD3) 0.0364 0.1003 0.1388
Loa Loa (eye worm) hypothetical protein 0.0108 0.0269 0.0372
Plasmodium vivax vivapain-2 0.005 0.0104 0.1034
Schistosoma mansoni amine GPCR 0.0057 0.0123 0.0123
Echinococcus granulosus Protein patched homolog 1 0.0068 0.0154 0.0154
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0008 0.0011
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) histone deacetylase 7A 0.013 0.0333 0.0461
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0001 0.0005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Schistosoma mansoni patched 1 0.0068 0.0154 0.0154
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0364 0.1003 0.5018
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0036 0.0062 0.0338
Mycobacterium ulcerans hypothetical protein 0.0043 0.0084 0.0455
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0069 0.5744
Onchocerca volvulus 0.0027 0.0037 0.0051
Echinococcus granulosus histone deacetylase 3 0.0364 0.1003 0.1003
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.012 0.0603
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0206 0.0206
Schistosoma mansoni histone deacetylase 4 5 0.013 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0077
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0149
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0111 0.0277 0.1505
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0036 0.0062 0.0338
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0001 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0108 0.0269 0.0372
Giardia lamblia Nitric oxide synthase, inducible 0.0023 0.0025 0.0206
Onchocerca volvulus 0.0027 0.0037 0.0051
Echinococcus granulosus neuropeptides capa receptor 0.0057 0.0123 0.0123
Schistosoma mansoni growth hormone secretagogue receptor 0.0057 0.0123 0.0123
Schistosoma mansoni cathepsin F (C01 family) 0.005 0.0104 0.0104
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0037 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0046 0.025
Echinococcus granulosus cathepsin l1 0.005 0.0104 0.0104
Onchocerca volvulus 0.0111 0.0277 0.0383
Echinococcus multilocularis aldo keto reductase 0.0111 0.0277 0.0277
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0057 0.0123 0.0123
Loa Loa (eye worm) TYRA-2 protein 0.0057 0.0123 0.017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0123 0.0123
Trypanosoma brucei prostaglandin f synthase 0.0111 0.0277 0.1505
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0058 0.0316
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Onchocerca volvulus Cathepsin L homolog 0.005 0.0104 0.0144
Onchocerca volvulus 0.005 0.0104 0.0144
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.019 0.0263
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0131 0.0181
Echinococcus granulosus aldo keto reductase 0.0111 0.0277 0.0277
Trichomonas vaginalis histone deacetylase, putative 0.0364 0.1003 0.5018
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0012 0.0099
Brugia malayi Steroid receptor seven-up type 2 0.0108 0.0269 0.0372
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0037 0.0037
Plasmodium falciparum aldo-keto reductase, putative 0.0045 0.0087 0.0872
Loa Loa (eye worm) intermediate filament protein 0.0081 0.019 0.0264
Plasmodium vivax aldehyde reductase, putative 0.0045 0.0087 0.0872
Onchocerca volvulus 0.0051 0.0105 0.0145
Echinococcus multilocularis RUN 0.0139 0.0358 0.0358
Loa Loa (eye worm) hypothetical protein 0.0364 0.1003 0.1388
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0173 0.0456 0.0631
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Entamoeba histolytica cysteine protease, putative 0.005 0.0104 0.0776
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Brugia malayi CHE-14 protein 0.0068 0.0154 0.0213
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0046 0.025
Loa Loa (eye worm) hypothetical protein 0.0108 0.0269 0.0372
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Toxoplasma gondii glyoxalase I, putative 0.0188 0.0498 0.4062
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.005 0.0104 0.0144
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0433 0.2169
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0008 0.0042
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0051 0.0105 0.0145
Onchocerca volvulus 0.0057 0.0123 0.017
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0016 0.0005 0.0005
Mycobacterium ulcerans hypothetical protein 0.0043 0.0084 0.0455
Echinococcus multilocularis G-protein coupled receptor, putative 0.0057 0.0123 0.0123
Trypanosoma brucei trypanothione reductase 0.0049 0.01 0.0545
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.0317 0.1726
Trichomonas vaginalis histone deacetylase, putative 0.0364 0.1003 0.5018
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0108 0.0269 0.0372
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Echinococcus multilocularis Ankyrin 0.0015 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.0078 0.0183 0.0183
Schistosoma mansoni intermediate filament proteins 0.0081 0.019 0.019
Onchocerca volvulus Bile acid receptor homolog 0.0108 0.0269 0.0372
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0777 0.389
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0051 0.0105 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0108 0.0269 0.0372
Echinococcus granulosus slit 2 protein 0.0441 0.1225 0.1225
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0068 0.0154 0.0154
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Plasmodium vivax flavodoxin domain containing protein 0.0023 0.0025 0.0251
Schistosoma mansoni hypothetical protein 0.0344 0.0947 0.0947
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0026 0.0034 0.0183
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.019 0.0264
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Schistosoma mansoni tyrosine kinase 0.0077 0.0181 0.0181
Echinococcus multilocularis histone deacetylase 7 0.013 0.0333 0.0333
Trypanosoma cruzi histone deacetylase, putative 0.013 0.0333 0.1814
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0045 0.0087 0.0437
Echinococcus multilocularis histone deacetylase 8 0.013 0.0333 0.0333
Echinococcus multilocularis histone deacetylase 6 0.013 0.0333 0.0333
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0034 0.0183
Echinococcus multilocularis somatostatin receptor 0.0057 0.0123 0.0123
Brugia malayi Dopamine receptor 0.0057 0.0123 0.017
Plasmodium falciparum pyruvate kinase 2 0.0018 0.001 0.0097
Schistosoma mansoni hypothetical protein 0.0441 0.1225 0.1225
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Loa Loa (eye worm) fibroinase 0.005 0.0104 0.0144
Schistosoma mansoni organic anion transporter 0.0027 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Giardia lamblia DINP protein human, muc B family 0.0021 0.0018 0.0146
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0057 0.0123 0.0123
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0012 0.0099
Schistosoma mansoni hypothetical protein 0.0139 0.0358 0.0358
Schistosoma mansoni amine GPCR 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Entamoeba histolytica aldose reductase, putative 0.0111 0.0277 0.2548
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0441 0.1225 0.1696
Entamoeba histolytica alcohol dehydrogenase, putative 0.0045 0.0087 0.0609
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0003 0.0015
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.019 0.019
Brugia malayi neuropeptide F receptor 0.0057 0.0123 0.017
Echinococcus multilocularis g-protein coupled receptor 0.0057 0.0123 0.0123
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0123 0.0123
Schistosoma mansoni agrin 0.0019 0.0012 0.0012
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Schistosoma mansoni hypothetical protein 0.0424 0.1176 0.1176
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0057 0.0123 0.0123
Plasmodium vivax vivapain-1 0.0026 0.0033 0.0334
Onchocerca volvulus Putative cubilin 0.0441 0.1225 0.1696
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0074 0.0402
Mycobacterium leprae Possible oxidoreductase 0.0045 0.0087 0.0989
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0104 0.0519
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0364 0.1003 0.5018
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0281 0.1531
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Echinococcus granulosus Polycystic kidney disease protein 0.0139 0.0358 0.0358
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0219 0.0219
Plasmodium vivax SET domain protein, putative 0.0091 0.0219 0.2186
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.0777 0.7687
Onchocerca volvulus 0.0057 0.0123 0.017
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0058 0.008
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0003 0.0023
Onchocerca volvulus 0.0057 0.0123 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Brugia malayi Death domain containing protein 0.0015 0.0002 0.0002
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0007 0.0009
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0001 0.0005
Brugia malayi polk-prov protein 0.003 0.0046 0.0064
Echinococcus granulosus agrin 0.0019 0.0012 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0005 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0104 0.0519
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0033 0.0334
Onchocerca volvulus 0.0057 0.0123 0.017
Leishmania major cytochrome P450 reductase, putative 0.0023 0.0025 0.0137
Brugia malayi Cytochrome P450 family protein 0.0036 0.0062 0.0086
Brugia malayi steroid hormone receptor 0.0108 0.0269 0.0372
Schistosoma mansoni neuropeptide receptor 0.0057 0.0123 0.0123
Onchocerca volvulus Phospholipase A2 homolog 0.0095 0.0233 0.0322
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0104 0.0519
Leishmania major cytochrome p450-like protein 0.0036 0.0062 0.0338
Echinococcus multilocularis cathepsin L cysteine protease 0.005 0.0104 0.0104
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0433 0.2169
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0007 0.0037
Echinococcus multilocularis cathepsin L 0.0026 0.0033 0.0033
Onchocerca volvulus 0.0057 0.0123 0.017
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0277 0.0383
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0037 0.0037
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0057 0.0123 0.0123
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0069 0.0377
Trichomonas vaginalis histone deacetylase, putative 0.0364 0.1003 0.5018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0009
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0017
Onchocerca volvulus 0.0441 0.1225 0.1696
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0304 0.2482
Echinococcus multilocularis lipoxygenase domain containing protein 0.0139 0.0358 0.0358
Leishmania major cathepsin L-like protease 0.0192 0.0511 0.2781
Giardia lamblia Aldose reductase 0.0111 0.0277 0.2256
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0123 0.017
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0074 0.037
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.0099 0.118
Onchocerca volvulus 0.0027 0.0037 0.0051
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0058 0.0316
Brugia malayi jmjC domain containing protein 0.0061 0.0133 0.0185
Onchocerca volvulus 0.0711 0.1999 0.2767
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.0317 0.8616
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0058 0.008
Entamoeba histolytica hypothetical protein 0.0076 0.0176 0.1514
Loa Loa (eye worm) hypothetical protein 0.0186 0.0492 0.0682
Loa Loa (eye worm) Notch2 0.0441 0.1225 0.1696
Onchocerca volvulus Chorion peroxidase homolog 0.2531 0.7224 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.0281 0.1531
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0036 0.0062 0.0338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0165 0.0433 0.0433
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0057 0.0123 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Plasmodium vivax vivapain-3 0.0026 0.0033 0.0334
Loa Loa (eye worm) hypothetical protein 0.0165 0.0433 0.06
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.004 0.0072 0.01
Loa Loa (eye worm) hypothetical protein 0.0099 0.0243 0.0336
Brugia malayi Cathepsin L-like precursor 0.005 0.0104 0.0144
Mycobacterium ulcerans hypothetical protein 0.0043 0.0084 0.0455
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0036 0.0062 0.0338
Trichomonas vaginalis set domain proteins, putative 0.0711 0.1999 1
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0045 0.0087 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0036 0.0062 0.0338
Echinococcus granulosus neuropeptide s receptor 0.1446 0.4111 0.4111
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0036 0.0062 0.0338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0052 0.0262
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0007 0.0009
Onchocerca volvulus Neuropeptide F receptor homolog 0.0057 0.0123 0.017
Echinococcus multilocularis neurogenic locus protein delta 0.0441 0.1225 0.1225
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0008 0.0078
Onchocerca volvulus 0.0057 0.0123 0.017
Echinococcus granulosus cytochrome P450 2K1 0.0036 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0051
Loa Loa (eye worm) hypothetical protein 0.004 0.0072 0.01
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.0097
Plasmodium vivax glyoxalase I, putative 0.0188 0.0498 0.4962
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0777 0.389
Echinococcus granulosus sterol regulatory element binding protein 0.0068 0.0154 0.0154
Brugia malayi neuropeptide F receptor 0.0057 0.0123 0.017
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.0507 0.0507
Onchocerca volvulus 0.0057 0.0123 0.017
Loa Loa (eye worm) glutathione reductase 0.0049 0.01 0.0139
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0057 0.0123 0.0123
Schistosoma mansoni lamin 0.0081 0.019 0.019
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0178 0.0178
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0057 0.0123 0.017
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0036 0.0062 0.0338
Brugia malayi Cadherin domain containing protein 0.0441 0.1225 0.1696
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0051 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0051
Brugia malayi N-terminal motif family protein 0.0186 0.0492 0.0682
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0059 0.0295
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0057 0.0123 0.0123
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.012 0.0167
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0026 0.0034 0.0336
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0005 0.0029
Loa Loa (eye worm) nuclear hormone receptor 0.0051 0.0105 0.0145
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0099 0.0984
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0004
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.0099 0.0805
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0057 0.0123 0.0123
Trypanosoma cruzi cysteine peptidase, putative 0.0192 0.0511 0.2781
Mycobacterium leprae conserved hypothetical protein 0.0049 0.0099 0.1362
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0023 0.0025 0.0126
Brugia malayi intermediate filament protein 0.0081 0.019 0.0264
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.012 0.0948
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Onchocerca volvulus 0.0057 0.0123 0.017
Echinococcus granulosus neurogenic locus notch protein 0.0441 0.1225 0.1225
Brugia malayi FAD binding domain containing protein 0.0026 0.0034 0.0047
Schistosoma mansoni hypothetical protein 0.008 0.019 0.019
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.0777 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0058 0.0474
Brugia malayi NADH-dependent xylose reductase 0.0045 0.0087 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Echinococcus multilocularis lamin dm0 0.0081 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0074 0.0402
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.0777 0.7687
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.0507 0.0507
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0359 0.1953
Brugia malayi hypoxia-induced factor 1 0.0147 0.0381 0.0527
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0105 0.0105
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0123 0.0123
Echinococcus granulosus orexin receptor type 2 0.0057 0.0123 0.0123
Onchocerca volvulus Peroxidasin homolog 0.2531 0.7224 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0042
Onchocerca volvulus 0.0081 0.019 0.0264
Brugia malayi jmjC domain containing protein 0.0057 0.0124 0.0171
Loa Loa (eye worm) hypothetical protein 0.0159 0.0416 0.0576
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0108 0.0269 0.0269
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0001 0.0006
Mycobacterium tuberculosis Probable reductase 0.0112 0.0281 0.1531
Echinococcus multilocularis nuclear receptor nhr 48 0.0051 0.0105 0.0105
Brugia malayi Dopamine receptor protein 1 0.0057 0.0123 0.017
Echinococcus granulosus lipoxygenase domain containing protein 0.0139 0.0358 0.0358
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0034 0.017
Entamoeba histolytica aldose reductase, putative 0.0111 0.0277 0.2548
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0433 0.2169
Brugia malayi G protein-coupled receptor F59B2.13 0.0057 0.0123 0.017
Echinococcus granulosus 7TM GPCR rhodopsin 0.0057 0.0123 0.0123
Echinococcus granulosus cathepsin L cysteine proteinase 0.005 0.0104 0.0104
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0058 0.008
Onchocerca volvulus 0.0027 0.0037 0.0051
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0277 0.0277
Schistosoma mansoni nuclear hormone receptor 0.0108 0.0269 0.0269
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0088 0.0122
Loa Loa (eye worm) hypothetical protein 0.0026 0.0034 0.0047
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0088 0.0122
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0085 0.0581
Schistosoma mansoni opsin-like receptor 0.0057 0.0123 0.0123
Echinococcus granulosus fmrfamide receptor 0.0057 0.0123 0.0123
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0459 0.2296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0033 0.0056
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Brugia malayi Cathepsin L-like precursor 0.005 0.0104 0.0144
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0026 0.0034 0.0183
Echinococcus granulosus protein jagged 1 0.0441 0.1225 0.1225
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0033 0.0182
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0057 0.0123 0.0123
Brugia malayi hypothetical protein 0.0139 0.0358 0.0495
Echinococcus granulosus Solute carrier family 22 5 0.202 0.5758 0.5758
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Onchocerca volvulus 0.0111 0.0277 0.0383
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0033 0.0167
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0777 0.389
Onchocerca volvulus 0.0111 0.0277 0.0383
Brugia malayi RE15519p 0.0057 0.0123 0.017
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0088 0.048
Schistosoma mansoni histone deacetylase 4 5 0.013 0.0333 0.0333
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0003 0.0003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0007 0.0009
Toxoplasma gondii exonuclease III APE 0.0056 0.012 0.0983
Loa Loa (eye worm) histone deacetylase 11 0.013 0.0333 0.0461
Schistosoma mansoni coup transcription factor 0.0108 0.0269 0.0269
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0057 0.0123 0.0123
Echinococcus granulosus neuropeptide FF receptor 2 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0051
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0123 0.0123
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0009
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0084 0.0861
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0057 0.0123 0.017
Echinococcus multilocularis FTZ F1 alpha 0.0108 0.0269 0.0269
Echinococcus multilocularis aldehyde reductase 0.0066 0.0148 0.0148
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0149
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0108 0.0269 0.0269
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0252 0.0682 0.0944
Schistosoma mansoni hypothetical protein 0.0344 0.0947 0.0947
Loa Loa (eye worm) hypothetical protein 0.0091 0.0219 0.0303
Onchocerca volvulus 0.0057 0.0123 0.017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0104 0.0519
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0037 0.0051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0123 0.0123
Schistosoma mansoni cathepsin s 0.0017 0.0007 0.0007
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0219 0.1789
Echinococcus granulosus histone deacetylase 0.013 0.0333 0.0333
Loa Loa (eye worm) cytochrome P450 0.0036 0.0062 0.0086
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.0124 0.0124
Schistosoma mansoni tyrosine kinase 0.0046 0.0092 0.0092
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0123 0.017
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0173 0.0456 0.0631
Loa Loa (eye worm) doublecortin family protein 0.0139 0.0358 0.0495
Trichomonas vaginalis sulfite reductase, putative 0.0026 0.0034 0.0169
Leishmania major histone deacetylase, putative 0.013 0.0333 0.1814
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0188 0.0498 0.271
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0003 0.0003
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0042
Echinococcus granulosus delta-like protein 1 0.0441 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.01 0.01
Echinococcus granulosus neuropeptide receptor A26 0.1446 0.4111 0.4111
Brugia malayi putative neuropeptide receptor NPR1 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0051
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0069 0.0565
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0003 0.0004
Echinococcus granulosus protein jagged 2 0.0441 0.1225 0.1225
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0033 0.0056
Onchocerca volvulus 0.005 0.0104 0.0144
Onchocerca volvulus Protein ultraspiracle homolog 0.0108 0.0269 0.0372
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0026 0.0034 0.0034
Toxoplasma gondii histone deacetylase HDAC1 0.013 0.0333 0.2719
Loa Loa (eye worm) hypothetical protein 0.0139 0.0358 0.0495
Echinococcus multilocularis cathepsin l cysteine peptidase 0.005 0.0104 0.0104
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0165 0.0433 0.06
Brugia malayi hypothetical protein 0.0043 0.0083 0.0115
Brugia malayi latrophilin 2 splice variant baaae 0.0174 0.0458 0.0634
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0043 0.0083 0.0115
Toxoplasma gondii histone deacetylase HDAC4 0.013 0.0333 0.2719
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0832 0.2346 0.2346
Toxoplasma gondii aldose reductase, putative 0.0111 0.0277 0.2256
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0036 0.0062 0.0338
Brugia malayi notch-like transmembrane receptor 0.0441 0.1225 0.1696
Loa Loa (eye worm) hypothetical protein 0.0068 0.0154 0.0213
Echinococcus multilocularis protein patched 0.0068 0.0154 0.0154
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.0042
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0036 0.0062 0.0338
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0037 0.0051
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Echinococcus granulosus g protein coupled receptor 0.0057 0.0123 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0052 0.0262
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0036 0.0062 0.0338
Loa Loa (eye worm) hypothetical protein 0.0254 0.0689 0.0954
Schistosoma mansoni histone deacetylase 0.0364 0.1003 0.1003
Trypanosoma brucei histone deacetylase 4 0.013 0.0333 0.1814
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0433 0.2169
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0133 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0041 0.0203
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0033 0.0182
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0277 0.0383
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Loa Loa (eye worm) G-protein coupled receptor 0.0057 0.0123 0.017
Schistosoma mansoni cathepsin F (C01 family) 0.005 0.0104 0.0104
Brugia malayi Animal haem peroxidase family protein 0.2531 0.7224 1
Echinococcus multilocularis cysteine protease 0.005 0.0104 0.0104
Schistosoma mansoni notch 0.0441 0.1225 0.1225
Schistosoma mansoni cell polarity protein 0.0441 0.1225 0.1225
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0032 0.0317
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Brugia malayi G-protein coupled receptor 0.0057 0.0123 0.017
Onchocerca volvulus 0.0099 0.0243 0.0336
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0165 0.0433 0.2359
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0165 0.0433 0.0433
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0085 0.0424
Brugia malayi jmjC domain containing protein 0.0015 0.0003 0.0004
Echinococcus granulosus histone deacetylase 7 0.013 0.0333 0.0333
Echinococcus granulosus notch 0.0441 0.1225 0.1225
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0002 0.0002
Onchocerca volvulus Peroxidase homolog 0.2531 0.7224 1
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0033 0.0182
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.1176 0.1176
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0021 0.0021
Loa Loa (eye worm) oxidoreductase 0.0111 0.0277 0.0383
Echinococcus granulosus FTZ F1 alpha 0.0108 0.0269 0.0269
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0084 0.0455
Schistosoma mansoni histone deacetylase 0.0364 0.1003 0.1003
Onchocerca volvulus 0.0043 0.0083 0.0115
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.0099 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0036 0.0062 0.0338
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0001 0.0006
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0058 0.0314
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0003 0.0003
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.007 0.0702
Plasmodium vivax glyoxalase I, putative 0.0043 0.0084 0.0833
Trypanosoma cruzi aldo/keto reductase, putative 0.0045 0.0087 0.0476
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0057 0.0123 0.0123
Brugia malayi hypothetical protein 0.0159 0.0416 0.0576
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0021 0.0029
Echinococcus multilocularis neurogenic locus notch protein 4 0.0441 0.1225 0.1225
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0058 0.0579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0057 0.0123 0.017
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Brugia malayi nuclear receptor RXR 0.0051 0.0105 0.0145
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0042
Echinococcus granulosus G protein coupled receptor 139 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0074 0.0402
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0777 0.389
Brugia malayi CHD4 protein 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0057 0.0123 0.017
Mycobacterium ulcerans glyoxalase GloA 0.0043 0.0084 0.0455
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0036 0.0062 0.0338
Leishmania major cathepsin L-like protease 0.005 0.0104 0.0565
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0123 0.0123
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0057 0.0123 0.0123
Brugia malayi Calcitonin receptor-like protein seb-1 0.0254 0.0689 0.0954
Echinococcus granulosus dro:myosuppressin receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Brugia malayi Animal haem peroxidase family protein 0.2531 0.7224 1
Brugia malayi Melatonin receptor type 1A 0.0057 0.0123 0.017
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.001 0.008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0042
Schistosoma mansoni tyrosine kinase 0.0146 0.0377 0.0377
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0149
Entamoeba histolytica hypothetical protein 0.0076 0.0176 0.1514
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0074 0.0402
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0001 0.0001
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0003 0.0015
Brugia malayi M-phase phosphoprotein, mpp8 0.0099 0.0243 0.0336
Schistosoma mansoni nuclear receptor nhr-48 0.0051 0.0105 0.0105
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0003 0.0003
Trichomonas vaginalis histone deacetylase, putative 0.0364 0.1003 0.5018
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0008 0.0078
Brugia malayi Calcium binding EGF domain containing protein 0.0441 0.1225 0.1696
Brugia malayi Cathepsin L-like precursor 0.0034 0.0056 0.0077
Onchocerca volvulus 0.0043 0.0083 0.0115
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.001 0.0097
Echinococcus multilocularis neuropeptide s receptor 0.1446 0.4111 0.4111
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0123 0.0123
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0074 0.0402
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0108 0.0269 0.0269
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.012 0.0983
Echinococcus granulosus serotonin receptor 0.0057 0.0123 0.0123
Mycobacterium tuberculosis Conserved protein 0.0045 0.0087 0.0476
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0057 0.0123 0.017
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0459 0.2296
Mycobacterium ulcerans hypothetical protein 0.0043 0.0084 0.0455
Trypanosoma cruzi cruzipain precursor, putative 0.0192 0.0511 0.2781
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0033 0.0182
Echinococcus granulosus histone deacetylase 6 0.013 0.0333 0.0333
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0066 0.0332
Schistosoma mansoni neuropeptide receptor 0.0057 0.0123 0.0123
Echinococcus granulosus histone deacetylase 8 0.013 0.0333 0.0333
Schistosoma mansoni zinc finger protein 0.0051 0.0105 0.0105
Echinococcus multilocularis protein jagged 1 0.0441 0.1225 0.1225
Echinococcus multilocularis 0.0036 0.0062 0.0062
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0057 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0095 0.0233 0.0233
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0277 0.1383
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0003 0.0003
Echinococcus multilocularis pyruvate kinase 0.0035 0.0058 0.0058
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0036 0.0062 0.0338
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0037 0.0051
Leishmania major cathepsin L-like protease 0.005 0.0104 0.0565
Trypanosoma cruzi cysteine peptidase, putative 0.005 0.0104 0.0565
Plasmodium falciparum cysteine proteinase falcipain 3 0.005 0.0104 0.1034
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0015 0.0003 0.0004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0108 0.0269 0.0269
Brugia malayi ecdysone receptor 0.0051 0.0105 0.0145
Onchocerca volvulus 0.0441 0.1225 0.1696
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0108 0.0269 0.0269
Leishmania major histone deacetylase, putative 0.0364 0.1003 0.5461
Echinococcus granulosus ecdysone induced protein 78C 0.0108 0.0269 0.0269
Leishmania major hypothetical protein, conserved 0.0015 0.0003 0.0015
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0012 0.0017
Echinococcus multilocularis cpg binding protein 0.0063 0.0141 0.0141
Brugia malayi histone deacetylase 11 0.013 0.0333 0.0461
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0003 0.0003
Plasmodium falciparum pyruvate kinase 0.0035 0.0058 0.0579
Entamoeba histolytica aldose reductase, putative 0.0111 0.0277 0.2548
Schistosoma mansoni histone deacetylase hda2 0.013 0.0333 0.0333
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0058 0.008
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0036 0.0062 0.0338
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0108 0.0269 0.0269
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.0507 0.0507
Loa Loa (eye worm) G-protein coupled receptor 0.0057 0.0123 0.017
Brugia malayi PAS domain containing protein 0.0047 0.0095 0.0132
Brugia malayi Animal haem peroxidase family protein 0.2531 0.7224 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0009
Echinococcus multilocularis neuropeptide receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0052 0.0262
Schistosoma mansoni neuropeptide F-like receptor 0.0057 0.0123 0.0123
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0071 0.0071
Echinococcus granulosus somatostatin receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0108 0.0269 0.0269
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.0099 0.0805
Schistosoma mansoni neuropeptide receptor 0.0057 0.0123 0.0123
Echinococcus multilocularis slit 2 protein 0.0441 0.1225 0.1225
Brugia malayi Nuclear hormone receptor-like 1 0.0108 0.0269 0.0372
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0051 0.0105 0.0105
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0057 0.0123 0.0123
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0364 0.1003 0.5018
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0036 0.0062 0.0338
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0249 0.0674 0.0674
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0083 0.0453
Echinococcus granulosus thyroid hormone receptor alpha 0.0051 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0034 0.017
Brugia malayi nuclear receptor NHR-88 0.0051 0.0105 0.0145
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0078 0.0181 0.0907
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.0381 0.0527
Echinococcus granulosus Nuclear hormone receptor HR96 0.0051 0.0105 0.0105
Brugia malayi putative neuropeptide receptor 0.0057 0.0123 0.017
Loa Loa (eye worm) steroid hormone receptor 0.0108 0.0269 0.0372
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0003 0.0028
Leishmania major cathepsin L-like protease 0.005 0.0104 0.0565
Echinococcus granulosus protein jagged 1 0.0441 0.1225 0.1225
Plasmodium falciparum glyoxalase I 0.0188 0.0498 0.4962
Schistosoma mansoni tyrosine kinase 0.0078 0.0183 0.0183
Brugia malayi Serotonin receptor 0.0057 0.0123 0.017
Brugia malayi Cathepsin L-like precursor 0.005 0.0104 0.0144
Trypanosoma cruzi histone deacetylase 1, putative 0.0364 0.1003 0.5461
Brugia malayi EGF-like domain containing protein 0.0441 0.1225 0.1696
Toxoplasma gondii cytochrome p450 superfamily protein 0.0036 0.0062 0.0506
Brugia malayi EGF-like domain containing protein 0.0441 0.1225 0.1696
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0057 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0033 0.0167
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0037 0.0051
Toxoplasma gondii histone deacetylase HDAC5 0.0131 0.0334 0.2722
Loa Loa (eye worm) hypothetical protein 0.0139 0.0358 0.0495
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0001 0.0006
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0188 0.0498 0.0689
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0008 0.0042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0017
Loa Loa (eye worm) blistered cuticle protein 3 0.2531 0.7224 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Toxoplasma gondii glyoxalase family protein 0.0043 0.0084 0.0682
Brugia malayi Cadherin domain containing protein 0.0441 0.1225 0.1696
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) histone deacetylase 1 0.0364 0.1003 0.1388
Brugia malayi Histone deacetylase family protein 0.013 0.0333 0.0461
Trypanosoma brucei aldo/keto reductase, putative 0.0045 0.0087 0.0476
Giardia lamblia Hypothetical protein 0.0023 0.0025 0.0206
Brugia malayi hypothetical protein 0.0027 0.0037 0.0051
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0059 0.0322
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0104 0.0519
Schistosoma mansoni neuropeptide f receptor 76f 0.0057 0.0123 0.0123
Brugia malayi FAD binding domain containing protein 0.0016 0.0005 0.0007
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0045 0.0087 0.0121
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0043 0.0083 0.0115
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0277 0.0277
Brugia malayi CXXC zinc finger family protein 0.006 0.0131 0.0181
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0165 0.0433 0.2359
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Trypanosoma cruzi cysteine peptidase, putative 0.0192 0.0511 0.2781
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0058 0.0316
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0191 0.0507 0.0507
Brugia malayi Cathepsin L-like precursor 0.005 0.0104 0.0144
Plasmodium vivax histone deacetylase, putative 0.013 0.0333 0.3322
Schistosoma mansoni biogenic amine receptor 0.0057 0.0123 0.0123
Echinococcus granulosus cathepsin l1 0.0034 0.0056 0.0056
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0057 0.0123 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0123 0.0123
Onchocerca volvulus 0.0043 0.0083 0.0115
Brugia malayi hypothetical protein 0.0025 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0051
Loa Loa (eye worm) papain family cysteine protease containing protein 0.005 0.0104 0.0144
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0277 0.0277
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0057 0.0123 0.017
Leishmania major trypanothione reductase 0.0049 0.01 0.0545
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0058 0.008
Onchocerca volvulus 0.0111 0.0277 0.0383
Schistosoma mansoni rab6-interacting 0.0139 0.0358 0.0358
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0008 0.0042
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0074 0.0402
Echinococcus granulosus neuropeptide Y receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0051
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0085 0.0461
Echinococcus multilocularis musashi 0.0081 0.019 0.019
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0682 0.3413
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Toxoplasma gondii aldo-keto reductase 0.0045 0.0087 0.0713
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0008 0.0064
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0043 0.0083 0.0453
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0059 0.0322
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0036 0.0062 0.0338
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0777 0.389
Leishmania major pyruvate kinase 0.0035 0.0058 0.0316
Onchocerca volvulus 0.0441 0.1225 0.1696
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.0333 0.0333
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Brugia malayi Cytochrome P450 family protein 0.0045 0.0088 0.0122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0123 0.0123
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0057 0.0123 0.0123
Brugia malayi prostaglandin transporter 0.0027 0.0037 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0108 0.0269 0.0372
Brugia malayi nuclear receptor NHR-88 0.0108 0.0269 0.0372
Schistosoma mansoni steroid hormone receptor ad4bp 0.0108 0.0269 0.0269
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Brugia malayi hypothetical protein 0.0016 0.0006 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0003 0.0015
Plasmodium falciparum thioredoxin reductase 0.0017 0.0008 0.0078
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0083 0.0115
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0173 0.0456 0.0456
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0078 0.0183 0.0183
Echinococcus multilocularis L aminoadipate semialdehyde 0.0173 0.0456 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0059 0.0295
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0108 0.0269 0.0372
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0078 0.0181 0.0907
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.019 0.0263
Echinococcus multilocularis neurogenic locus notch protein 0.0441 0.1225 0.1225
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0108 0.0269 0.0269
Trypanosoma cruzi histone deacetylase, putative 0.013 0.0333 0.1814
Brugia malayi nuclear hormone receptor 0.0108 0.0269 0.0372
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0033 0.0167
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0001 0.0001
Echinococcus granulosus histone deacetylase 6 0.013 0.0333 0.0333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0433 0.2169
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Echinococcus granulosus neurogenic locus protein delta 0.0441 0.1225 0.1225
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0277 0.1383
Brugia malayi Histone deacetylase 1 0.0364 0.1003 0.1388
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Echinococcus granulosus single minded 2 0.0035 0.006 0.006
Leishmania major pyruvate kinase 0.0035 0.0058 0.0316
Brugia malayi Latrophilin receptor protein 2 0.008 0.019 0.0263
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0033 0.0046
Plasmodium vivax vivapain-2 0.005 0.0104 0.1034
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.0124 0.0124
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0036 0.0062 0.0338
Mycobacterium ulcerans epoxide hydrolase EphA 0.0159 0.0417 0.2269
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0008 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0104 0.0519
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0087 0.0437
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0123 0.0123
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0085 0.0461
Schistosoma mansoni cytochrome P450 0.0036 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0219 0.0219
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0058 0.0316
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0088 0.0122
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0105 0.0105
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0087 0.0437
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0045 0.0087 0.0872
Loa Loa (eye worm) notch protein 0.0441 0.1225 0.1696
Brugia malayi nuclear hormone receptor family member nhr-6 0.0051 0.0105 0.0145
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Onchocerca volvulus 0.0027 0.0037 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0682 0.3413
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Plasmodium falciparum thioredoxin reductase 0.0049 0.01 0.0998
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Echinococcus multilocularis Niemann Pick C1 protein 0.0068 0.0154 0.0154
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0277 0.0277
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0056 0.0279
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0359 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.019 0.0264
Schistosoma mansoni amine GPCR 0.0057 0.0123 0.0123
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0008 0.0078
Echinococcus granulosus hypothetical protein 0.0111 0.0277 0.0277
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0058 0.0316
Echinococcus multilocularis lamin 0.0081 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0002
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0057 0.0123 0.0123
Schistosoma mansoni aldo-keto reductase 0.0111 0.0277 0.0277
Giardia lamblia GTOR 0.0044 0.0085 0.0691
Schistosoma mansoni pyruvate kinase 0.0018 0.001 0.001
Brugia malayi Peroxidasin 0.2531 0.7224 1
Loa Loa (eye worm) hypothetical protein 0.0468 0.1301 0.1801
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0085 0.0424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0104 0.0519
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0002 0.0002
Trypanosoma brucei histone deacetylase, putative 0.013 0.0333 0.1814
Loa Loa (eye worm) oxidoreductase 0.0111 0.0277 0.0383
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0281 0.1531
Loa Loa (eye worm) oxidoreductase 0.0111 0.0277 0.0383
Echinococcus granulosus 7tm_1 domain containing protein 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0111 0.0277 0.0383
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0099 0.0537
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.005 0.0104 0.0519
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0036 0.0062 0.0338
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0045 0.0087 0.0713
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0036 0.0062 0.0338
Loa Loa (eye worm) oxidoreductase 0.0111 0.0277 0.0383
Loa Loa (eye worm) oxidoreductase 0.0043 0.0083 0.0115
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0108 0.0269 0.0372
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0277 0.0277
Onchocerca volvulus 0.0057 0.0123 0.017
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.0281 0.7422
Onchocerca volvulus 0.0081 0.019 0.0264
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0373 0.0516
Schistosoma mansoni hypothetical protein 0.0057 0.0123 0.0123
Trypanosoma brucei histone deacetylase 2 0.013 0.0333 0.1814
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0254 0.0689 0.0954
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0105 0.0105
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0033 0.0182
Brugia malayi glutathione reductase 0.0049 0.01 0.0139
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0433 0.06
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0682 0.3413
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0037 0.0051
Schistosoma mansoni lipoxygenase 0.0832 0.2346 0.2346
Loa Loa (eye worm) hypothetical protein 0.0174 0.0458 0.0634
Brugia malayi bHLH-PAS transcription factor 0.0035 0.006 0.0083
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0001 0.0006
Echinococcus granulosus nuclear receptor nhr 48 0.0051 0.0105 0.0105
Brugia malayi Pre-SET motif family protein 0.0625 0.1752 0.2425
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Echinococcus multilocularis geminin 0.0344 0.0947 0.0947
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3406 0.9738 0.9738
Trichomonas vaginalis histone deacetylase, putative 0.0364 0.1003 0.5018
Onchocerca volvulus 0.0019 0.0012 0.0017
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0654 0.1837 1
Chlamydia trachomatis pyruvate kinase 0.0035 0.0058 0.5664
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0057 0.0123 0.0123
Plasmodium vivax histone deacetylase, putative 0.013 0.0333 0.3322
Loa Loa (eye worm) hypothetical protein 0.005 0.0104 0.0144
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0057 0.0123 0.017
Schistosoma mansoni hypothetical protein 0.008 0.019 0.019
Schistosoma mansoni hypothetical protein 0.0441 0.1225 0.1225
Onchocerca volvulus 0.0111 0.0277 0.0383
Echinococcus granulosus biogenic amine 5HT receptor 0.0057 0.0123 0.0123
Trypanosoma cruzi major cysteine proteinase, putative 0.0151 0.0393 0.2138
Brugia malayi SPARC precursor 0.0019 0.0012 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0001 0.0005
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0051 0.0105 0.0105
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0003 0.0003
Onchocerca volvulus Phospholipase A2 homolog 0.0095 0.0233 0.0322
Brugia malayi ecdysteroid receptor 0.0108 0.0269 0.0372
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0036 0.0062 0.0338
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0625 0.1752 0.2425
Echinococcus granulosus dnaJ subfamily B 0.0424 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0017
Brugia malayi larval opioid receptor 0.0057 0.0123 0.017
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0036 0.0062 0.0338
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0165 0.0433 0.2359
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0108 0.0269 0.0372
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.0124 0.0124
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0045 0.0087 0.0121
Onchocerca volvulus Cathepsin L homolog 0.005 0.0104 0.0144
Onchocerca volvulus 0.0043 0.0083 0.0115
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.012 0.0656
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.012 0.0167
Echinococcus granulosus pyruvate kinase 0.0018 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0001 0.0005
Schistosoma mansoni adenoreceptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0108 0.0269 0.0372
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0108 0.0269 0.0269
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 0.0682 0.0944
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0108 0.0269 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0085 0.0424
Plasmodium falciparum LCCL domain-containing protein 0.0139 0.0358 0.3568
Brugia malayi Animal haem peroxidase family protein 0.2531 0.7224 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0013 0.0013
Brugia malayi nuclear receptor NHR-67 0.0051 0.0105 0.0145
Brugia malayi sulfakinin receptor protein 0.0057 0.0123 0.017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.019 0.019
Brugia malayi Uncoordinated protein 44 0.0015 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0036 0.0062 0.0338
Loa Loa (eye worm) hypothetical protein 0.0108 0.0269 0.0372
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0108 0.0269 0.0372
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Schistosoma mansoni thyroid hormone receptor 0.0357 0.0984 0.0984
Schistosoma mansoni notch 0.0441 0.1225 0.1225
Toxoplasma gondii histone deacetylase HDAC3 0.0364 0.1003 0.8185
Echinococcus granulosus neuropeptide receptor 0.0057 0.0123 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0033 0.0056
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.012 0.0656
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0036 0.0062 0.0338
Giardia lamblia Pyruvate kinase 0.0018 0.001 0.008
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0074 0.0402
Leishmania major cathepsin L-like protease 0.005 0.0104 0.0565
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.0099 0.0537
Echinococcus multilocularis histone deacetylase 0.013 0.0333 0.0333
Trypanosoma brucei unspecified product 0.0034 0.0055 0.0302
Echinococcus granulosus phd:f box containing protein 0.0015 0.0003 0.0003
Mycobacterium leprae Conserved hypothetical protein 0.0066 0.0148 0.2999
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0359 0.1953
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0036 0.0062 0.0338
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.012 0.1201
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0008 0.0042
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0085 0.0461
Schistosoma mansoni histone deacetylase hda2 0.013 0.0333 0.0333
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0021 0.003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0108 0.0269 0.0372
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0032 0.0317
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0108 0.0269 0.0269
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0069 0.0377
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0026 0.0034 0.0183
Toxoplasma gondii histone deacetylase HDAC2 0.0364 0.1003 0.8185
Brugia malayi flavodoxin family protein 0.0026 0.0034 0.0047
Entamoeba histolytica cysteine proteinase, putative 0.005 0.0104 0.0776
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0204 0.0545 0.0545
Echinococcus multilocularis fmrfamide receptor 0.0057 0.0123 0.0123
Plasmodium falciparum glutathione reductase 0.0049 0.01 0.0998
Mycobacterium ulcerans oxidoreductase 0.0111 0.0277 0.1505
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0057 0.0123 0.0123
Schistosoma mansoni lamin 0.0081 0.019 0.019
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Echinococcus multilocularis aldo keto reductase 0.0111 0.0277 0.0277
Brugia malayi GCC2 and GCC3 family protein 0.0441 0.1225 0.1696
Echinococcus multilocularis protein jagged 1 0.0441 0.1225 0.1225
Echinococcus granulosus cysteine protease 0.0026 0.0033 0.0033
Schistosoma mansoni laminin gamma-3 chain 0.0441 0.1225 0.1225
Schistosoma mansoni myosin xvIII 0.0057 0.0123 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Schistosoma mansoni rab6-interacting 0.0139 0.0358 0.0358
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0777 0.389
Mycobacterium ulcerans hypothetical protein 0.0043 0.0084 0.0455
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0051 0.0105 0.0105
Brugia malayi Histone deacetylase family protein 0.013 0.0333 0.0461
Echinococcus granulosus alpha 1A adrenergic receptor 0.0057 0.0123 0.0123
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0008 0.0647
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Trypanosoma cruzi histone deacetylase 1, putative 0.0364 0.1003 0.5461
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0051 0.0105 0.0105
Mycobacterium leprae Conserved hypothetical protein 0.0036 0.0062 0.0146
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0032 0.0317
Brugia malayi hypothetical protein 0.0076 0.0176 0.0243
Echinococcus multilocularis epidermal growth factor receptor 0.0146 0.0377 0.0377
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0045 0.0087 0.0713
Brugia malayi Cathepsin L-like precursor 0.005 0.0104 0.0144
Echinococcus granulosus neurogenic locus notch protein 0.0441 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0037 0.0066 0.0092
Echinococcus granulosus RUN 0.0139 0.0358 0.0358
Schistosoma mansoni notch 0.0441 0.1225 0.1225
Onchocerca volvulus Peroxidase homolog 0.2531 0.7224 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0123 0.0123
Schistosoma mansoni cpg binding protein 0.0063 0.0141 0.0141
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0002 0.0002
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.0099 0.0984
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0277 0.1383
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0059 0.0322
Echinococcus multilocularis expressed protein 0.0019 0.0012 0.0012
Echinococcus multilocularis neuropeptides capa receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Brugia malayi hypothetical protein 0.0051 0.0105 0.0145
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0043 0.0083 0.0115
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0108 0.0269 0.0372
Onchocerca volvulus Slit protein homolog 0.0441 0.1225 0.1696
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0254 0.0689 0.0954
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0211 0.0211
Echinococcus multilocularis neuropeptide receptor A26 0.1446 0.4111 0.4111
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0085 0.0461
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Schistosoma mansoni hypothetical protein 0.0036 0.0062 0.0062
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0074 0.0402
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0281 0.1531
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.01 0.0545
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0057 0.0123 0.0123
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0085 0.0461
Echinococcus granulosus death domain containing protein 0.0015 0.0002 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0191 0.0507 0.0702
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0033 0.0182
Onchocerca volvulus 0.0111 0.0277 0.0383
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0191 0.0507 0.0702
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0033 0.0046
Echinococcus granulosus Ankyrin 0.0015 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0008 0.0064
Onchocerca volvulus 0.005 0.0104 0.0144
Echinococcus granulosus g protein coupled receptor 0.0057 0.0123 0.0123
Echinococcus granulosus hypothetical protein 0.0057 0.0123 0.0123
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0133 0.0133
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0056 0.0077
Schistosoma mansoni hypothetical protein 0.0076 0.0176 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0123 0.0123
Loa Loa (eye worm) TK/EGFR protein kinase 0.0146 0.0377 0.0521
Schistosoma mansoni pol-related 0.0111 0.0277 0.0277
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0078 0.0181 0.0907
Entamoeba histolytica alcohol dehydrogenase, putative 0.0045 0.0087 0.0609
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0032 0.0173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0059 0.0295
Echinococcus multilocularis histone deacetylase 1 0.0364 0.1003 0.1003
Schistosoma mansoni hypothetical protein 0.0441 0.1225 0.1225
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0277 0.0277
Echinococcus multilocularis sterol regulatory element binding protein 0.0068 0.0154 0.0154
Echinococcus granulosus neuropeptide receptor 0.0057 0.0123 0.0123
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Brugia malayi orphan nuclear receptor NR2E1 0.0051 0.0105 0.0145
Brugia malayi Inositol-1 0.0038 0.0069 0.0096
Leishmania major prostaglandin f synthase, putative 0.0111 0.0277 0.1505
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0108 0.0269 0.0269
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0165 0.0433 0.2359
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.019 0.0264
Trypanosoma brucei histone deacetylase 1 0.0364 0.1003 0.5461
Echinococcus granulosus Nuclear hormone receptor HR96 0.0051 0.0105 0.0105
Schistosoma mansoni gynecophoral canal protein 0.0043 0.0084 0.0084
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0045 0.0087 0.0476
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Schistosoma mansoni single-minded 0.0047 0.0095 0.0095
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0123 0.0123
Schistosoma mansoni aldo-keto reductase 0.0111 0.0277 0.0277
Brugia malayi nuclear receptor RXR 0.0057 0.0123 0.017
Brugia malayi Cathepsin L-like precursor 0.0034 0.0056 0.0077
Schistosoma mansoni inositol monophosphatase 0.0038 0.0069 0.0069
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0188 0.0498 0.271
Echinococcus granulosus lipoxygenase domain containing protein 0.0139 0.0358 0.0358
Plasmodium vivax histone deacetylase 1, putative 0.0364 0.1003 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0018 0.0097
Loa Loa (eye worm) hypothetical protein 0.0099 0.0243 0.0336
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0111 0.0277 0.7269
Brugia malayi hypothetical protein 0.0139 0.0358 0.0495
Loa Loa (eye worm) hypothetical protein 0.004 0.0072 0.01
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0219 0.0219
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0159 0.0417 0.2269
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0001 0.0006
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0002 0.0002
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0012 0.0017
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0011 0.0011
Echinococcus multilocularis fatty acid binding protein FABP2 0.0034 0.0055 0.0055
Echinococcus multilocularis cathepsin L cysteine protease 0.005 0.0104 0.0104
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0178 0.0178
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0058 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0074 0.0402
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0001 0.0001
Loa Loa (eye worm) inositol-1 0.0038 0.0069 0.0096
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Brugia malayi ORL1-like opioid receptor 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Onchocerca volvulus 0.0057 0.0123 0.017
Plasmodium vivax histone deacetylase 2, putative 0.013 0.0333 0.3322
Echinococcus multilocularis neuropeptide receptor 0.0057 0.0123 0.0123
Echinococcus multilocularis neuropeptide FF receptor 2 0.0057 0.0123 0.0123
Echinococcus multilocularis follistatin 0.0019 0.0012 0.0012
Leishmania major protein kinase, putative 0.0016 0.0006 0.0031
Entamoeba histolytica hypothetical protein 0.0049 0.0099 0.0724
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0043 0.0084 0.0116
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0191 0.0507 0.0507
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0043 0.0084 0.0455
Brugia malayi jmjC domain containing protein 0.0015 0.0003 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0036 0.0062 0.0338
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0277 0.0277
Schistosoma mansoni thyroid hormone receptor 0.0357 0.0984 0.0984
Brugia malayi Doublecortin family protein 0.0139 0.0358 0.0495
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0057 0.0123 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0007 0.0037
Brugia malayi SET domain containing protein 0.0016 0.0004 0.0006
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0033 0.0182
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0211 0.0211
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0111 0.0277 0.0277
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0085 0.0581
Brugia malayi EGF-like domain containing protein 0.0441 0.1225 0.1696
Onchocerca volvulus Dual oxidase homolog 0.2531 0.7224 1
Onchocerca volvulus 0.005 0.0104 0.0144
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0008 0.0042
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Schistosoma mansoni hypothetical protein 0.0057 0.0123 0.0123
Brugia malayi nuclear hormone receptor 0.0051 0.0105 0.0145
Echinococcus multilocularis aldo keto reductase 0.0111 0.0277 0.0277
Echinococcus granulosus g protein coupled receptor 0.0057 0.0123 0.0123
Onchocerca volvulus 0.005 0.0104 0.0144
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0051 0.0105 0.0145
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0682 0.3413
Schistosoma mansoni pyruvate kinase 0.0035 0.0058 0.0058
Onchocerca volvulus 0.0095 0.0233 0.0322
Schistosoma mansoni hypothetical protein 0.0441 0.1225 0.1225
Echinococcus multilocularis histone deacetylase 6 0.013 0.0333 0.0333
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0433 0.2169
Toxoplasma gondii EGF family domain-containing protein 0.0441 0.1225 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.012 1
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0008 0.0039
Onchocerca volvulus 0.0045 0.0087 0.0121
Leishmania major cathepsin L-like protease 0.0192 0.0511 0.2781
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0028 0.0039
Echinococcus granulosus pyruvate kinase 0.0035 0.0058 0.0058
Loa Loa (eye worm) oxidoreductase 0.0111 0.0277 0.0383
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0373 0.0373
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0018 0.0097
Echinococcus multilocularis neuropeptides capa receptor 0.0057 0.0123 0.0123
Echinococcus multilocularis protein jagged 2 0.0441 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0108 0.0269 0.0372
Brugia malayi Furin-like cysteine rich region family protein 0.0146 0.0377 0.0521
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0654 0.1837 1
Brugia malayi lactoylglutathione lyase 0.0188 0.0498 0.0689
Echinococcus granulosus sex peptide receptor 0.0057 0.0123 0.0123
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.0317 0.1726
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0081 0.0803
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.012 0.0656
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0001 0.0001
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0037 0.0201
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0068 0.0154 0.0213
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0036 0.0062 0.0338
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0074 0.0402
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0069 0.0377
Schistosoma mansoni tyrosine kinase 0.0077 0.0181 0.0181
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0057 0.0123 0.0123
Schistosoma mansoni pyruvate kinase 0.0035 0.0058 0.0058
Brugia malayi EGF-like domain containing protein 0.0441 0.1225 0.1696
Trypanosoma cruzi histone deacetylase, putative 0.013 0.0333 0.1814
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.012 0.012
Leishmania major hypothetical protein, conserved 0.0025 0.0032 0.0173
Schistosoma mansoni follistatin 0.0019 0.0012 0.0012
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0085 0.0461
Echinococcus multilocularis neural cadherin 0.0441 0.1225 0.1225
Giardia lamblia Aldose reductase 0.0111 0.0277 0.2256
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Onchocerca volvulus 0.0057 0.0123 0.017
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0026 0.0034 0.0183
Onchocerca volvulus 0.0051 0.0105 0.0145
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0032 0.0259
Trypanosoma cruzi cysteine peptidase, putative 0.0192 0.0511 0.2781
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0012 0.0017
Brugia malayi photoreceptor-specific nuclear receptor 0.0108 0.0269 0.0372
Onchocerca volvulus 0.0441 0.1225 0.1696
Schistosoma mansoni biogenic amine (5HT) receptor 0.0057 0.0123 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Loa Loa (eye worm) melatonin receptor type 1A 0.0057 0.0123 0.017
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0043 0.0083 0.0679
Brugia malayi Dopamine receptor protein 2 0.0057 0.0123 0.017
Onchocerca volvulus 0.005 0.0104 0.0144
Plasmodium falciparum glutathione reductase 0.0017 0.0008 0.0078
Schistosoma mansoni neuropeptide receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) animal heme peroxidase 0.2531 0.7224 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0057 0.0123 0.0123
Giardia lamblia Pyruvate kinase 0.0035 0.0058 0.0474
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Echinococcus multilocularis survival motor neuron protein 1 0.0468 0.1301 0.1301
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0058 0.008
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0233 0.0322
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0002 0.0002
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Echinococcus granulosus cathepsin l cysteine peptidase 0.005 0.0104 0.0104
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0069 0.0346
Echinococcus granulosus cpg binding protein 0.0063 0.0141 0.0141
Echinococcus granulosus voltage gated potassium channel subunit 0.0045 0.0087 0.0087
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0085 0.0117
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.012 0.0603
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0108 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0095 0.0233 0.0322
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0111 0.0277 0.1383
Onchocerca volvulus Neurogenic locus notch homolog 0.0441 0.1226 0.1697
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0123 0.0123
Echinococcus granulosus histone deacetylase 1 0.0364 0.1003 0.1003
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0026 0.0034 0.0183
Loa Loa (eye worm) hypothetical protein 0.013 0.0333 0.0461
Mycobacterium tuberculosis Conserved protein 0.0043 0.0084 0.0455
Entamoeba histolytica hypothetical protein 0.0076 0.0176 0.1514
Echinococcus multilocularis pyruvate kinase 0.0027 0.0037 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0052 0.0262
Echinococcus multilocularis voltage gated potassium channel subunit 0.0045 0.0087 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0036 0.0062 0.0338
Echinococcus granulosus pyruvate kinase 0.0018 0.001 0.001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0139 0.0358 0.0358
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0149
Onchocerca volvulus 0.0035 0.006 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0036 0.0062 0.0338
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0058 0.0316
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0108 0.0269 0.0372
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0074 0.0402
Echinococcus granulosus intermediate filament protein 0.0081 0.019 0.019
Brugia malayi Animal haem peroxidase family protein 0.2531 0.7224 1
Onchocerca volvulus 0.0139 0.0358 0.0495
Echinococcus granulosus neuropeptide Y receptor 0.0057 0.0123 0.0123
Schistosoma mansoni histone deacetylase 1 2 3 0.013 0.0333 0.0333
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0682 0.3413
Plasmodium falciparum histone deacetylase 2 0.013 0.0333 0.3322
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0043 0.0084 0.0116
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0057 0.0123 0.017
Brugia malayi Pre-SET motif family protein 0.0091 0.0219 0.0303
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0074 0.0402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0052 0.0262
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0036 0.0062 0.0338
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0008 0.0292
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.012 0.1201
Brugia malayi hypothetical protein 0.0099 0.0243 0.0336
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.01 0.01
Onchocerca volvulus 0.0057 0.0123 0.017
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0059 0.0295
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0046 0.0092 0.0092
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0003 0.0004
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0026 0.0034 0.0183
Echinococcus multilocularis neurogenic locus notch protein 0.0441 0.1225 0.1225
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0176 0.0176
Echinococcus multilocularis allatostatin A receptor 0.0057 0.0123 0.0123
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.003 0.0149
Plasmodium falciparum aldehyde reductase, putative 0.0045 0.0087 0.0872
Brugia malayi cathepsin L-like precursor 0.0034 0.0056 0.0077
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0036 0.0062 0.0338
Schistosoma mansoni notch 0.0441 0.1226 0.1226
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0441 0.1225 0.1225
Echinococcus multilocularis dro:myosuppressin receptor 0.0057 0.0123 0.0123
Onchocerca volvulus 0.0102 0.0251 0.0348
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0277 0.0383
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0008 0.0042
Loa Loa (eye worm) hypothetical protein 0.0079 0.0186 0.0258
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trichomonas vaginalis aldo-keto reductase, putative 0.0045 0.0087 0.0437
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0078 0.0181 0.148
Onchocerca volvulus 0.005 0.0104 0.0144
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0008 0.0042
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0002 0.0002
Echinococcus multilocularis histone deacetylase 6 0.013 0.0333 0.0333
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.0099 0.0537
Echinococcus granulosus survival motor neuron protein 1 0.0468 0.1301 0.1301
Echinococcus granulosus lamin dm0 0.0081 0.019 0.019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0123 0.0123
Echinococcus granulosus lamin 0.0081 0.019 0.019
Echinococcus multilocularis ecdysone induced protein 78C 0.0108 0.0269 0.0269
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0108 0.0269 0.0372
Leishmania major cytochrome p450-like protein 0.0036 0.0062 0.0338
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0081 0.0658
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0123 0.0123
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0108 0.0269 0.0372
Loa Loa (eye worm) DR-78 0.0051 0.0105 0.0145
Entamoeba histolytica cysteine protease, putative 0.0026 0.0033 0.0056
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0057 0.0123 0.0123
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0123 0.0123
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0081 0.0403
Onchocerca volvulus 0.0173 0.0456 0.0631
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0057 0.0123 0.017
Brugia malayi hypothetical protein 0.0051 0.0105 0.0145
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0108 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0108 0.0269 0.0372
Loa Loa (eye worm) neuropeptide F receptor 0.0057 0.0123 0.017
Echinococcus multilocularis 0.0045 0.0088 0.0088
Brugia malayi hypothetical protein 0.0027 0.0037 0.0051
Schistosoma mansoni fatty acid binding protein 0.0034 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0043 0.0216
Loa Loa (eye worm) histone deacetylase 0.013 0.0333 0.0461
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0001 0.0001
Echinococcus granulosus follistatin 0.0019 0.0012 0.0012
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.0042
Echinococcus granulosus histone deacetylase 6 0.013 0.0333 0.0333
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0176 0.0463 0.252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.005 0.0104 0.0519
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0123 0.0123
Echinococcus granulosus aldehyde reductase 0.0066 0.0148 0.0148
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0012 0.0017
Echinococcus granulosus allatostatin A receptor 0.0057 0.0123 0.0123
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0036 0.0062 0.0338
Mycobacterium leprae putative cytochrome p450 0.0036 0.0062 0.0146
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.0507 0.0507
Loa Loa (eye worm) FAD binding domain-containing protein 0.0016 0.0005 0.0007
Schistosoma mansoni RAR-like nuclear receptor 0.0108 0.0269 0.0269
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0057 0.0123 0.0123
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.01 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0005 0.0029
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.007 0.0575
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.012 0.0656
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0026 0.0034 0.0034
Loa Loa (eye worm) cysteine protease 0.005 0.0104 0.0144
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.012 0.0656
Echinococcus multilocularis fmrfamide receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.012 0.012
Echinococcus granulosus cathepsin L 0.0026 0.0033 0.0033
Schistosoma mansoni amine GPCR 0.0057 0.0123 0.0123
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0361 0.0361
Schistosoma mansoni hypothetical protein 0.008 0.019 0.019
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0032 0.0173
Echinococcus granulosus pyruvate kinase 0.0018 0.001 0.001
Echinococcus multilocularis G protein coupled receptor 139 0.0057 0.0123 0.0123
Leishmania major DNA polymerase kappa, putative 0.0021 0.0018 0.0097
Onchocerca volvulus Cathepsin F homolog 0.005 0.0104 0.0144
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0191 0.0507 0.0507
Echinococcus multilocularis pyruvate kinase 0.0018 0.001 0.001
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0033 0.0056
Echinococcus multilocularis microtubule associated protein 2 0.3498 1 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0176 0.0176
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0084 0.0418
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0069 0.0422
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.019 0.019
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0074 0.0402
Brugia malayi nuclear hormone receptor family member odr-7 0.0051 0.0105 0.0145
Trypanosoma cruzi aldo/keto reductase, putative 0.0111 0.0277 0.1505
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0036 0.0062 0.0338
Brugia malayi Nuclear hormone receptor E75 0.0051 0.0105 0.0145
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0056 0.0285
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0124 0.0124
Toxoplasma gondii cathepsin CPL 0.005 0.0104 0.0846
Echinococcus granulosus peroxidasin 0.2531 0.7224 0.7224
Schistosoma mansoni hypothetical protein 0.0249 0.0674 0.0674
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0108 0.0269 0.0269
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0042
Echinococcus multilocularis pyruvate kinase 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) animal heme peroxidase 0.2531 0.7224 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.012 0.1464
Loa Loa (eye worm) cytochrome P450 family protein 0.0074 0.0172 0.0238
Echinococcus multilocularis agrin 0.0019 0.0012 0.0012
Brugia malayi EGF-like domain containing protein 0.0441 0.1225 0.1696
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0069 0.0346
Leishmania major histone deacetylase, putative 0.0364 0.1003 0.5461
Echinococcus multilocularis pyruvate kinase 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Giardia lamblia Histone deacetylase 0.0364 0.1003 0.8185
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0084 0.0418
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0108 0.0269 0.0372
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0777 0.389
Onchocerca volvulus 0.2531 0.7224 1
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0008
Schistosoma mansoni loxhd1 0.0139 0.0358 0.0358
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0051 0.0105 0.0105
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0055 0.0302
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Schistosoma mansoni netrin receptor unc5 0.0015 0.0002 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0057 0.0123 0.0123
Trypanosoma cruzi histone deacetylase, putative 0.013 0.0333 0.1814
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0034 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0052 0.0262
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0057 0.0123 0.0123
Echinococcus granulosus fibropellin Ia 0.0441 0.1225 0.1225
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0003 0.0023
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0069 0.0377
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0037 0.0051
Onchocerca volvulus 0.2531 0.7224 1
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0058 0.0291
Brugia malayi EGF-like domain containing protein 0.0441 0.1225 0.1696
Brugia malayi Thioredoxin reductase 0.0049 0.01 0.0139
Trypanosoma cruzi p450 reductase, putative 0.0026 0.0034 0.0183
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0009
Echinococcus granulosus g-protein coupled receptor 0.0057 0.0123 0.0123
Leishmania major cathepsin L-like protease 0.0192 0.0511 0.2781
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.0777 0.389
Plasmodium vivax JmjC domain containing protein 0.0015 0.0003 0.0028
Brugia malayi hypothetical protein 0.0468 0.1301 0.1801
Schistosoma mansoni opsin-like receptor 0.0057 0.0123 0.0123
Onchocerca volvulus 0.006 0.0131 0.0181
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Trichomonas vaginalis aldo/keto reductase, putative 0.0111 0.0277 0.1383
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.0099 0.8189
Onchocerca volvulus 0.0099 0.0243 0.0336
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0032 0.0173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0192 0.0511 0.2781
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0186 0.0492 0.0682
Schistosoma mansoni fatty acid binding protein 0.0034 0.0055 0.0055
Loa Loa (eye worm) histone deacetylase 3 0.0364 0.1003 0.1388
Toxoplasma gondii thioredoxin reductase 0.0049 0.01 0.0817
Schistosoma mansoni cytochrome P450 reductase 0.0026 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0108 0.0269 0.0372
Brugia malayi Protein kinase domain containing protein 0.0046 0.0092 0.0128
Brugia malayi conserved hypotetical protein 0.0051 0.0105 0.0145
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0123 0.0123
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0085 0.0085
Plasmodium falciparum nitric oxide synthase, putative 0.0026 0.0034 0.0336
Loa Loa (eye worm) hypothetical protein 0.0108 0.0269 0.0372
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0188 0.0498 0.271
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0058
Plasmodium vivax unspecified product 0.0026 0.0033 0.0334
Mycobacterium tuberculosis Conserved protein TB27.3 0.0043 0.0084 0.0455
Echinococcus granulosus tachykinin peptides receptor 99D 0.0057 0.0123 0.0123
Schistosoma mansoni tyrosine kinase 0.0077 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0037 0.0301
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0108 0.0269 0.0372
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.0099 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0036 0.0062 0.0338
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0051 0.0105 0.0145
Schistosoma mansoni microtubule-associated protein tau 0.3498 1 1
Onchocerca volvulus 0.0043 0.0083 0.0115
Schistosoma mansoni biogenic amine receptor 0.0057 0.0123 0.0123
Onchocerca volvulus Histone deacetylase 10 homolog 0.013 0.0333 0.0461
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0012 0.0099
Leishmania major aldo-keto reductase-like protein 0.0111 0.0277 0.1505
Echinococcus multilocularis protein dispatched 1 0.0068 0.0154 0.0154
Echinococcus granulosus neuropeptides capa receptor 0.0057 0.0123 0.0123
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0095 0.0095
Trypanosoma brucei histone deacetylase 3 0.013 0.0333 0.1814
Loa Loa (eye worm) hypothetical protein 0.008 0.019 0.0263
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0026 0.0034 0.0034
Echinococcus granulosus neurogenic locus notch protein 4 0.0441 0.1225 0.1225
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0001 0.0006
Brugia malayi jmjC domain containing protein 0.0015 0.0003 0.0004
Plasmodium falciparum cysteine proteinase falcipain 2b 0.005 0.0104 0.1034
Mycobacterium tuberculosis Probable oxidoreductase 0.0111 0.0277 0.1505
Brugia malayi Protein kinase domain containing protein 0.0015 0.0002 0.0002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0219 0.0219
Brugia malayi tailless protein 0.0051 0.0105 0.0145
Leishmania major cytochrome p450-like protein 0.0045 0.0088 0.048
Leishmania major cathepsin L-like protease 0.005 0.0104 0.0565
Loa Loa (eye worm) hypothetical protein 0.003 0.0046 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0682 0.3413
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0056 0.0056
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0147 0.0381 0.0381
Echinococcus multilocularis orexin receptor type 2 0.0057 0.0123 0.0123
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0108 0.0269 0.0372
Plasmodium falciparum histone deacetylase 1 0.0364 0.1003 1
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0083 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Brugia malayi Cathepsin L-like precursor 0.005 0.0104 0.0144
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0057 0.0123 0.0123
Echinococcus multilocularis neurogenic locus protein delta 0.0441 0.1225 0.1225
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0654 0.1837 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0012 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0104 0.0519
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) FAD binding domain-containing protein 0.0026 0.0034 0.0047
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0033 0.0056
Schistosoma mansoni lipoxygenase 0.0581 0.1628 0.1628
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0069 0.0069
Mycobacterium ulcerans putative regulatory protein 0.0035 0.006 0.0325
Echinococcus granulosus epidermal growth factor receptor 0.0146 0.0377 0.0377
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Plasmodium falciparum histone deacetylase, putative 0.013 0.0333 0.3322
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0111 0.0277 0.1505
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0123 0.0123
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0211 0.0211
Brugia malayi Cytochrome P450 family protein 0.0045 0.0088 0.0122
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Echinococcus granulosus Niemann Pick C1 protein 0.0068 0.0154 0.0154
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.0317 0.1726
Schistosoma mansoni alpha-1 adrenergic receptor 0.0057 0.0123 0.0123
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0249 0.0674 0.0674
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0069 0.0377
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.012 0.0656
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0002 0.0002
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0025 0.0032 0.0044
Echinococcus granulosus methionine synthase reductase 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0051
Echinococcus granulosus aldo keto reductase 0.0111 0.0277 0.0277
Brugia malayi EGF-like domain containing protein 0.0441 0.1225 0.1696
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0108 0.0269 0.0372
Plasmodium vivax unspecified product 0.0017 0.0007 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0042
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0026 0.0034 0.0183
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0042
Loa Loa (eye worm) TK/INSR protein kinase 0.0046 0.0092 0.0128
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0105 0.0105
Echinococcus multilocularis fatty acid binding protein FABP2 0.0034 0.0055 0.0055
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0043 0.0084 0.0084
Schistosoma mansoni peroxidasin 0.2531 0.7224 0.7224
Echinococcus multilocularis serotonin receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) ctsf protein 0.005 0.0104 0.0144
Brugia malayi Cytochrome P450 family protein 0.0074 0.0172 0.0238
Echinococcus granulosus peptide allatostatin:somatostatin 0.0057 0.0123 0.0123
Loa Loa (eye worm) nuclear receptor NHR-67 0.0051 0.0105 0.0145
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0074 0.0402
Echinococcus multilocularis dna polymerase kappa 0.004 0.0074 0.0074
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0008 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0074 0.0402
Echinococcus multilocularis serotonin receptor 0.0057 0.0123 0.0123
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0433 0.2169
Plasmodium falciparum cysteine proteinase falcipain 2a 0.005 0.0104 0.1034
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0036 0.0062 0.0338
Entamoeba histolytica histone deacetylase, putative 0.0364 0.1003 1
Onchocerca volvulus 0.0108 0.0269 0.0372
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0009 0.0044
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0033 0.0056
Onchocerca volvulus 0.0441 0.1225 0.1696
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0085 0.0117
Echinococcus multilocularis sex peptide receptor 0.0057 0.0123 0.0123
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0008
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0008 0.0078
Schistosoma mansoni retinoic acid receptor RXR 0.0204 0.0545 0.0545
Entamoeba histolytica cysteine proteinase, putative 0.005 0.0104 0.0776
Entamoeba histolytica hypothetical protein 0.0076 0.0176 0.1514
Schistosoma mansoni nuclear receptor 0.0051 0.0105 0.0105
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0057 0.0123 0.0123
Schistosoma mansoni biogenic amine receptor 0.0057 0.0123 0.0123
Brugia malayi hypothetical protein 0.0057 0.0123 0.017
Echinococcus granulosus protein jagged 2 0.0441 0.1225 0.1225
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0004
Schistosoma mansoni inositol monophosphatase 0.0038 0.0069 0.0069
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0046 0.0092 0.0092
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0036 0.0062 0.0338
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.007 0.0435
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0004
Schistosoma mansoni neuropeptide F-like receptor 0.0057 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Schistosoma mansoni peroxidasin 0.2531 0.7224 0.7224
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0034 0.0055 0.0077
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0046 0.0092 0.0092
Brugia malayi Calcium binding EGF domain containing protein 0.0441 0.1225 0.1696
Mycobacterium ulcerans hypothetical protein 0.0045 0.0087 0.0476
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0165 0.0433 0.0433
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0037 0.0037
Loa Loa (eye worm) acetyltransferase 0.0144 0.0373 0.0516
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.003 0.0149
Loa Loa (eye worm) hypothetical protein 0.0441 0.1225 0.1696
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0036 0.0062 0.0338
Echinococcus multilocularis cathepsin l cysteine peptidase 0.005 0.0104 0.0104
Schistosoma mansoni hypothetical protein 0.0057 0.0123 0.0123
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0441 0.1225 0.1696
Onchocerca volvulus Peroxidasin homolog 0.2531 0.7224 1
Brugia malayi histone deacetylase 1 (HD1) 0.0364 0.1003 0.1388
Schistosoma mansoni hypothetical protein 0.0015 0.0002 0.0002
Echinococcus multilocularis fibropellin Ia 0.0441 0.1225 0.1225
Schistosoma mansoni hypothetical protein 0.0441 0.1225 0.1225
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0087 0.0437
Onchocerca volvulus Putative protein 0.0043 0.0084 0.0116
Schistosoma mansoni histamine h1 receptor 0.0057 0.0123 0.0123
Schistosoma mansoni potassium channel beta 0.0045 0.0087 0.0087
Onchocerca volvulus 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.0095 0.0233 0.0322
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0037 0.0037
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0832 0.2346 0.2346
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0058 0.008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0123 0.0123
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0069 0.0346
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0036 0.0062 0.0338
Echinococcus multilocularis epidermal growth factor receptor 0.0078 0.0183 0.0183
Brugia malayi Phospholipase A2 family protein 0.0095 0.0233 0.0322
Mycobacterium ulcerans hypothetical protein 0.0043 0.0084 0.0455
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0111 0.0277 0.0277
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0088 0.048
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.01 0.0998
Echinococcus multilocularis histone deacetylase 3 0.0364 0.1003 0.1003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0027 0.0134
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0003
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0074 0.037
Brugia malayi G protein-coupled receptor 0.0057 0.0123 0.017
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0012 0.0017
Echinococcus multilocularis notch 0.0441 0.1225 0.1225
Mycobacterium tuberculosis Conserved protein 0.0043 0.0084 0.0455
Loa Loa (eye worm) hypothetical protein 0.0037 0.0066 0.0092
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0071 0.0071
Echinococcus multilocularis cysteine protease 0.005 0.0104 0.0104
Schistosoma mansoni septate junction protein 0.0441 0.1225 0.1225
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0013 0.0013
Trypanosoma brucei aldo-keto reductase, putative 0.0111 0.0277 0.1505
Echinococcus multilocularis pyruvate kinase 0.0035 0.0058 0.0058
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0033 0.0033
Schistosoma mansoni ap endonuclease 0.0056 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0105 0.0145
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0058 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0154 0.0771
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0012 0.0058
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0123 0.0123
Echinococcus granulosus pyruvate kinase 0.0035 0.0058 0.0058
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.003 0.0149
Schistosoma mansoni opsin-like receptor 0.0057 0.0123 0.0123
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.0777 0.6345
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0058 0.0291
Loa Loa (eye worm) animal heme peroxidase 0.2531 0.7224 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0003 0.0004
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0081 0.0658
Loa Loa (eye worm) animal heme peroxidase 0.2531 0.7224 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Brugia malayi Delta serrate ligand family protein 0.0441 0.1225 0.1696
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.0099 0.0537
Brugia malayi GnHR receptor homolog 0.0057 0.0123 0.017
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0036 0.0062 0.0338
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.01 0.0545
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Onchocerca volvulus 0.0043 0.0083 0.0115
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.0281 0.1531
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0018 0.01
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0654 0.1837 1
Schistosoma mansoni hypothetical protein 0.0441 0.1225 0.1225
Echinococcus granulosus L aminoadipate semialdehyde 0.0173 0.0456 0.0456
Onchocerca volvulus 0.0057 0.0123 0.017
Loa Loa (eye worm) hypothetical protein 0.2531 0.7224 1
Echinococcus multilocularis methionine synthase reductase 0.0016 0.0005 0.0005
Brugia malayi Muscle positioning protein 4 0.0441 0.1225 0.1696
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.004 0.0072 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0219 0.0219
Leishmania major histone deacetylase, putative 0.013 0.0333 0.1814
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0036 0.0062 0.0338
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0008 0.0647
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0011 0.0061
Echinococcus multilocularis Polycystic kidney disease protein 0.0139 0.0358 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0052 0.0262
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0069 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0074 0.0402
Loa Loa (eye worm) hypothetical protein 0.0039 0.0071 0.0098
Brugia malayi cytochrome P450 0.0036 0.0062 0.0086
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0108 0.0269 0.0269
Echinococcus granulosus aldo keto reductase 0.0111 0.0277 0.0277
Echinococcus multilocularis neuropeptide Y receptor 0.0057 0.0123 0.0123
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.0042
Brugia malayi Tachykinin-like peptides receptor 99D 0.0057 0.0123 0.017
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0002 0.0002
Schistosoma mansoni survival motor neuron protein 0.0095 0.0233 0.0233
Schistosoma mansoni organic anion transporter 0.0027 0.0037 0.0037
Brugia malayi Blistered cuticle protein 3 0.2531 0.7224 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0057 0.0123 0.017
Plasmodium vivax glutathione reductase, putative 0.0049 0.01 0.0998
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0056 0.0279
Brugia malayi Papain family cysteine protease containing protein 0.005 0.0104 0.0144
Brugia malayi hypothetical protein 0.2531 0.7224 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0111 0.0277 0.1383
Brugia malayi Serotonin receptor 0.0057 0.0123 0.017
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0012 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0108 0.0269 0.0372
Echinococcus multilocularis peroxidasin 0.2531 0.7224 0.7224
Schistosoma mansoni cpg binding protein 0.0063 0.0141 0.0141
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0111 0.0277 0.0383
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.017
Giardia lamblia High cysteine protein 0.0441 0.1225 1
Trypanosoma cruzi histone deacetylase, putative 0.013 0.0333 0.1814
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0033 0.0167
Onchocerca volvulus 0.0034 0.0056 0.0077
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0039
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0654 0.1837 1
Echinococcus granulosus epidermal growth factor receptor 0.0078 0.0183 0.0183
Echinococcus granulosus insulin receptor 0.0046 0.0092 0.0092

Activities

Activity type Activity value Assay description Source Reference
Change (functional) = -4 % The compound was evaluated for acute inhibition of cholesterol synthesis in rat; percent change of [14C]-cholesterol ChEMBL. 1875346
IC50 (binding) = 16 nM In vitro ability to inhibit solubilized, partially purified, rat liver HMG-CoA reductase ChEMBL. 1875346
Relative potency (ADMET) = 94 Relative potency of the compound was determined with respect to compactin ChEMBL. 1875346

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.