Detailed information for compound 135826

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 850.775 | Formula: C41H42N2O18
  • H donors: 8 H acceptors: 13 LogP: 2.54 Rotable bonds: 17
    Rule of 5 violations (Lipinski): 4
  • SMILES: COc1cccc2c1C(=O)c1c(C2=O)c(O)c2c(c1O)[C@@H](OC1OC(C)C(C(C1)NC(=O)OCc1ccc(cc1)OC(=O)NC(C(=O)O)CCC(=O)O)O)C[C@](C2)(O)C(=O)C
  • InChi: 1S/C41H42N2O18/c1-17-33(47)24(43-39(54)58-16-19-7-9-20(10-8-19)60-40(55)42-23(38(52)53)11-12-27(45)46)13-28(59-17)61-26-15-41(56,18(2)44)14-22-30(26)37(51)32-31(35(22)49)34(48)21-5-4-6-25(57-3)29(21)36(32)50/h4-10,17,23-24,26,28,33,47,49,51,56H,11-16H2,1-3H3,(H,42,55)(H,43,54)(H,45,46)(H,52,53)/t17?,23?,24?,26-,28?,33?,41-/m0/s1
  • InChiKey: ZKVPZFZNRKWFJR-HGHOOVHBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni phosphatidylserine receptor 0.0054 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0176 0.0387 0.0801
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0239
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0298
Leishmania major GTP-binding protein, putative 0.0021 0.0009 0.0235
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0375 0.087 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0084
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.0371 0.086 0.2462
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0425 0.0991 0.0991
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0081 0.0155 0.0216
Loa Loa (eye worm) hypothetical protein 0.0035 0.0044 0.0092
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0073 0.0073
Loa Loa (eye worm) MBCTL1 0.0053 0.0088 0.0182
Loa Loa (eye worm) beta-lactamase 0.0074 0.014 0.0289
Mycobacterium tuberculosis Conserved protein 0.0074 0.014 0.0175
Loa Loa (eye worm) bromodomain containing protein 0.0125 0.0262 0.0542
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0115 0.3684
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0155 0.0216
Brugia malayi Glycosyl hydrolases family 31 protein 0.0054 0.009 0.0187
Loa Loa (eye worm) hypothetical protein 0.0271 0.0617 0.1277
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0155 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0235 0.0327
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0254 0.0575 0.119
Echinococcus granulosus chromobox protein 2 0.0081 0.0155 0.0155
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.0544 0.0544
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.014 0.4491
Brugia malayi Latrophilin receptor protein 2 0.008 0.0154 0.0319
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0311 0.0432
Leishmania major DNA polymerase kappa, putative 0.0018 0.0003 0.0077
Chlamydia trachomatis replicative DNA helicase 0.0375 0.087 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0058 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0039 0.0054 0.0054
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.01 0.3227
Plasmodium vivax hypothetical protein, conserved 0.0119 0.0249 0.6184
Plasmodium falciparum flap endonuclease 1 0.0027 0.0025 0.1005
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0086 0.3442
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0 0.0001
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0017 0 0.0016
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0003 0.0122
Echinococcus multilocularis dna polymerase eta 0.0058 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.02
Echinococcus granulosus Smad4 0.0051 0.0083 0.0083
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0303 0.0695 0.0695
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0017 0 0.0001
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0 0.0001
Brugia malayi nuclear receptor NHR-67 0.003 0.0033 0.0068
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0154 0.0319
Echinococcus granulosus dnaJ subfamily B 0.083 0.1975 0.1975
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0064 0.0116 0.0239
Echinococcus multilocularis histone acetyltransferase myst4 0.0017 0.0000073783 0.0000073783
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0057 0.1817
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0006 0.0006
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0113 0.0235 0.0235
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0036 0.0904
Schistosoma mansoni coup transcription factor 0.0064 0.0116 0.0116
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0268 0.0611 0.1264
Loa Loa (eye worm) transcription factor SMAD2 0.0751 0.1783 0.3689
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0155 0.0216
Trypanosoma cruzi Ring finger domain/PHD-finger, putative 0.0017 0.0000073783 0.0002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0064 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0081 0.0155 0.0216
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.007 0.013 0.013
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0387 0.0538
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0155 0.0216
Echinococcus granulosus chromobox protein 1 0.0493 0.1156 0.1156
Brugia malayi Muscleblind-like protein 0.2006 0.4834 1
Onchocerca volvulus 0.0058 0.0101 0.0293
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0087
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0155 0.3856
Schistosoma mansoni hypothetical protein 0.008 0.0154 0.0154
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0155 0.3856
Trypanosoma brucei unspecified product 0.004 0.0057 0.1817
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0054 0.009 0.2881
Schistosoma mansoni ap endonuclease 0.0018 0.0004 0.0004
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0033 0.0033
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0278 0.0278
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0033 0.0096
Schistosoma mansoni hypothetical protein 0.0017 0.0000073783 0.0000073783
Echinococcus multilocularis neuropeptide receptor A26 0.045 0.1052 0.1052
Treponema pallidum recombinase A 0.0105 0.0214 0.0296
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0082 0.0234
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Echinococcus granulosus histone acetyltransferase myst3 0.0017 0.0000073783 0.0000073783
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.0371 0.086 0.2462
Echinococcus granulosus TRP transient receptor potential channel 0.0035 0.0044 0.0044
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0004 0.0123
Loa Loa (eye worm) RecQ helicase 0.0047 0.0073 0.0152
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0435 0.0435
Schistosoma mansoni requim req/dpf2 0.0017 0.0000073783 0.0000073783
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0033 0.0068
Echinococcus granulosus Chromobox protein 3 0.0081 0.0155 0.0155
Echinococcus granulosus flap endonuclease 1 0.0027 0.0025 0.0025
Loa Loa (eye worm) twinkle helicase 0.0107 0.0219 0.0454
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0145 0.0311 0.0432
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0006 0.0006
Echinococcus granulosus uro adherence factor A 0.0017 0.0000073783 0.0000073783
Leishmania major DNA polymerase eta, putative 0.0018 0.0003 0.0077
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0115 0.3684
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0051 0.0082 0.0234
Echinococcus granulosus lysine specific demethylase 5A 0.0218 0.0489 0.0489
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0268 0.0611 0.1264
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0435 0.0435
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0034 0.0042 0.0042
Brugia malayi hypothetical protein 0.0241 0.0544 0.1125
Entamoeba histolytica acyl-coA synthetase, putative 0.0051 0.0082 0.0114
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0239
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0387 0.0538
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0006 0.0006
Schistosoma mansoni zinc finger protein 0.0017 0.0000073783 0.0000073783
Echinococcus multilocularis mothers against decapentaplegic 6 0.0023 0.0015 0.0015
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.01 0.0208
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0086 0.2129
Loa Loa (eye worm) hypothetical protein 0.0056 0.0094 0.0195
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0017 0 0.0014
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.013 0.0275 0.057
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0017 0 0.0001
Brugia malayi beta-lactamase family protein 0.0074 0.014 0.0289
Plasmodium vivax P-type ATPase4, putative 0.0017 0 0.0012
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0088 0.0088
Echinococcus granulosus phd finger protein 10 0.0017 0.0000073783 0.0000073783
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.013 0.0275 0.0275
Loa Loa (eye worm) MH1 domain-containing protein 0.0023 0.0015 0.0031
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0054 0.009 0.2883
Plasmodium falciparum histone-lysine N-methyltransferase, H3 lysine-4 specific 0.0017 0.0000073783 0.0003
Echinococcus multilocularis peregrin 0.0146 0.0313 0.0313
Echinococcus multilocularis cpg binding protein 0.0075 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0219 0.0492 0.1019
Echinococcus multilocularis lysine specific demethylase 5B 0.0017 0.0000073783 0.0000073783
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.3287 0.7945 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0435 0.0435
Brugia malayi glutaminase DH11.1 0.0541 0.1273 0.2633
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0311 1
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0081 0.0155 0.6236
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3017 0.7288 0.9174
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0064 0.0116 0.0239
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0081 0.0155 0.0155
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0082 0.0114
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0058 0.01 0.0208
Echinococcus granulosus FTZ F1 alpha 0.0064 0.0116 0.0116
Trypanosoma brucei ISWI complex protein 0.0108 0.0222 0.7128
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0082 0.0114
Onchocerca volvulus 0.0057 0.0097 0.0282
Schistosoma mansoni hypothetical protein 0.0299 0.0685 0.0685
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0004 0.001
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0017 0 0.0001
Treponema pallidum replicative DNA helicase (dnaB) 0.0375 0.087 0.1209
Trichomonas vaginalis Heterochromatin protein, putative 0.0081 0.0155 0.0216
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0033 0.0033
Trypanosoma brucei protein kinase, putative 0.01 0.0202 0.6505
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0254 0.0575 0.119
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0064 0.0116 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0064 0.0116 0.0239
Brugia malayi hypothetical protein 0.0034 0.0042 0.0087
Trypanosoma cruzi Ring finger domain/PHD-finger, putative 0.0017 0.0000073783 0.0002
Echinococcus multilocularis Chromobox protein 3 0.0081 0.0155 0.0155
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0017 0 0.0001
Entamoeba histolytica hypothetical protein 0.002 0.0009 0.0012
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0003 0.0076
Echinococcus granulosus peregrin 0.0146 0.0313 0.0313
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0088 0.0088
Schistosoma mansoni importin beta-1 0.0028 0.0027 0.0027
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0081 0.0155 0.0155
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0036 0.0906
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0162 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Trypanosoma brucei unspecified product 0.004 0.0057 0.1817
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0113 0.0235 0.0327
Brugia malayi MH2 domain containing protein 0.0051 0.0083 0.0173
Schistosoma mansoni protein phosphatase 2C 0.0054 0.009 0.009
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0017 0 0.0001
Brugia malayi hypothetical protein 0.0017 0 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Brugia malayi hypothetical protein 0.0177 0.0389 0.0805
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0297 0.0681 0.1983
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0033 0.0033
Echinococcus multilocularis Smad4 0.0051 0.0083 0.0083
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.002 0.0651
Brugia malayi follicle stimulating hormone receptor 0.0221 0.0497 0.1028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0081 0.0155 0.0216
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0042 0.0061 0.0061
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.014 0.0399
Entamoeba histolytica hypothetical protein 0.0153 0.0331 0.046
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.2978 0.7195 1
Schistosoma mansoni SET domain protein 0.0036 0.0046 0.0046
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.002 0.0649
Brugia malayi Valyl-tRNA synthetase 0.0081 0.0155 0.0321
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.01 0.3227
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0113 0.0235 0.7558
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0611 0.0849
Leishmania major DNA damage repair protein, putative 0.0018 0.0003 0.0077
Echinococcus granulosus histone acetyltransferase myst4 0.0017 0.0000073783 0.0000073783
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0014 0.002
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0155 0.0216
Schistosoma mansoni transient receptor potential channel 0.0094 0.0188 0.0188
Schistosoma mansoni alpha glucosidase 0.0145 0.0311 0.0311
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0026 0.0026
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0003 0.0076
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.1455 0.3494 0.4398
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0036 0.1167
Brugia malayi hypothetical protein 0.003 0.0033 0.0068
Schistosoma mansoni intermediate filament proteins 0.0057 0.0097 0.0097
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0094 0.0187 0.026
Schistosoma mansoni ran 0.0021 0.0009 0.0009
Brugia malayi jmjC domain containing protein 0.0054 0.009 0.0185
Brugia malayi Glycosyl hydrolases family 31 protein 0.0145 0.0311 0.0643
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0025 0.0035
Leishmania major alpha glucosidase II subunit, putative 0.0145 0.0311 0.7907
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0012
Schistosoma mansoni myst histone acetyltransferase 0.0017 0.0000073783 0.0000073783
Echinococcus granulosus geminin 0.121 0.2898 0.2898
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0108 0.0108
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0435 0.0435
Echinococcus multilocularis FTZ F1 alpha 0.0064 0.0116 0.0116
Brugia malayi N-terminal motif family protein 0.0176 0.0387 0.0801
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.014 0.0194
Trichomonas vaginalis DNA polymerase eta, putative 0.0058 0.01 0.0139
Mycobacterium ulcerans hypothetical protein 0.0018 0.0003 0.0008
Toxoplasma gondii cation-transporting atpase family protein 0.0017 0 0.0012
Echinococcus granulosus ubiquitin specific protease 41 0.0113 0.0235 0.0235
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0034 0.0042 0.0087
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0097 0.0196 0.0196
Brugia malayi PHD-finger family protein 0.0056 0.0095 0.0196
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.013 0.0275 0.8861
Plasmodium falciparum phd finger protein, putative 0.0119 0.0249 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0154 0.0154
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0016 0.0016
Echinococcus granulosus lysosomal alpha glucosidase 0.0652 0.1544 0.1544
Schistosoma mansoni alpha-glucosidase 0.0561 0.1323 0.1323
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0004 0.0009
Echinococcus multilocularis transient receptor potential gamma protein 0.0094 0.0188 0.0188
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.014 0.014
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0004 0.0138
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0082 0.0234
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0036 0.1169
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.0051 0.1267
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0145 0.0311 0.0432
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0105 0.0214 0.2453
Onchocerca volvulus 0.143 0.3433 1
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0042 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0173 0.038 0.038
Plasmodium falciparum SNF2 helicase, putative 0.0017 0.0000073783 0.0003
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0036 0.0904
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0004 0.0123
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0003 0.0095
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0064 0.0116 0.0116
Brugia malayi Steroid receptor seven-up type 2 0.0064 0.0116 0.0239
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0003 0.0098
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0004 0.0097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0101 0.0208
Brugia malayi photoreceptor-specific nuclear receptor 0.0064 0.0116 0.0239
Brugia malayi jmjC domain containing protein 0.0054 0.009 0.0185
Schistosoma mansoni phd finger protein 0.0027 0.0024 0.0024
Toxoplasma gondii PHD-finger domain-containing protein 0.0017 0.0000073783 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0036 0.0036
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0004 0.0042
Leishmania major P-type H -ATPase, putative 0.0017 0 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0033 0.0033
Brugia malayi nuclear receptor NHR-88 0.0064 0.0116 0.0239
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0088 0.0172 0.0239
Echinococcus granulosus neuropeptide s receptor 0.045 0.1052 0.1052
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.01 0.0202 0.5144
Brugia malayi hypothetical protein 0.003 0.0033 0.0068
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.014 0.014
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0196 0.0435 0.09
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0155 0.0216
Trichomonas vaginalis esterase, putative 0.0074 0.014 0.0194
Schistosoma mansoni hypothetical protein 0.0108 0.0222 0.0222
Loa Loa (eye worm) steroid hormone receptor 0.0064 0.0116 0.0239
Brugia malayi CHD4 protein 0.0097 0.0196 0.0405
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0113 0.0235 0.0327
Schistosoma mansoni terminal deoxycytidyl transferase 0.0058 0.01 0.01
Loa Loa (eye worm) jmjC domain-containing protein 0.0054 0.009 0.0185
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.013 0.0275 0.7006
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0087
Trichomonas vaginalis chromobox protein, putative 0.0297 0.0681 0.0946
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0097 0.02
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0064 0.0116 0.0239
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0006 0.0008
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0155 0.0216
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.046 0.1076 0.2226
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0025 0.0035
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0033 0.0096
Loa Loa (eye worm) hypothetical protein 0.0444 0.1037 0.2146
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0033 0.0068
Onchocerca volvulus 0.0377 0.0876 0.2551
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0 0.0001
Echinococcus granulosus snurportin 1 0.0299 0.0685 0.0685
Brugia malayi jmjC domain containing protein 0.0218 0.0489 0.1012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0087 0.017 0.0236
Echinococcus multilocularis methyl CpG binding domain protein 2 0.012 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0054 0.009 0.0185
Brugia malayi CXXC zinc finger family protein 0.0058 0.0101 0.0208
Trypanosoma brucei DNA polymerase eta, putative 0.0058 0.01 0.3227
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0113 0.0235 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0202 0.0202
Echinococcus multilocularis Chromo domain 0.0081 0.0155 0.0155
Toxoplasma gondii PHD-finger domain-containing protein 0.0017 0.0000073783 0.0002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0054 0.009 0.0125
Loa Loa (eye worm) hypothetical protein 0.0241 0.0544 0.1125
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0051 0.0082 0.0234
Toxoplasma gondii PHD-finger domain-containing protein 0.0017 0.0000073783 0.0002
Plasmodium vivax copper-transporting ATPase, putative 0.0017 0 0.0012
Echinococcus multilocularis apoptotic protease activating factor 1 0.0096 0.0193 0.0193
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0113 0.0235 0.0235
Echinococcus granulosus mixed lineage leukemia protein mll 0.0022 0.0013 0.0013
Echinococcus multilocularis lysosomal alpha glucosidase 0.0652 0.1544 0.1544
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0611 0.0849
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0088 0.0088
Echinococcus granulosus methyl CpG binding domain protein 2 0.012 0.0252 0.0252
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0036 0.1462
Brugia malayi mothers against decapentaplegic homolog 3 0.0023 0.0015 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2978 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.017
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1257 0.3012 0.6232
Echinococcus granulosus mitogen activated protein kinase 3 0.01 0.0202 0.0202
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0145 0.0311 0.0432
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0088 0.0088
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.0371 0.086 0.1083
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0054 0.009 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0064 0.0116 0.0239
Mycobacterium ulcerans glutaminase 0.0541 0.1273 0.3642
Brugia malayi Pre-SET motif family protein 0.1257 0.3012 0.6232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Echinococcus multilocularis Zinc finger, DBF type 0.0017 0.0000073783 0.0000073783
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0033 0.0033
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0025 0.0052
Echinococcus multilocularis zinc finger protein 0.0142 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0081 0.0155 0.0321
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0064 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0087
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0006 0.0158
Leishmania major copper-transporting ATPase-like protein, putative 0.0017 0 0.0013
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0072 0.015
Plasmodium falciparum importin beta, putative 0.0028 0.0027 0.1093
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0081 0.0155 0.3856
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0202 0.6506
Trypanosoma cruzi P-type H+-ATPase, putative 0.0017 0 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0017 0 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0393 0.1125
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0022 0.0045
Brugia malayi nuclear receptor NHR-88 0.003 0.0033 0.0068
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0036 0.1167
Schistosoma mansoni zinc finger protein 0.0017 0.0000073783 0.0000073783
Brugia malayi Flap endonuclease-1 0.0027 0.0025 0.0052
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.046 0.1076 0.2226
Trypanosoma cruzi DNA repair protein, putative 0.0032 0.0038 0.1207
Loa Loa (eye worm) jmjC domain-containing protein 0.0054 0.009 0.0185
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0081 0.0155 0.0216
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0017 0 0.0014
Schistosoma mansoni chromobox protein 0.0081 0.0155 0.0155
Onchocerca volvulus 0.0074 0.014 0.0407
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0611 0.0849
Schistosoma mansoni smad 0.0023 0.0015 0.0015
Schistosoma mansoni transient receptor potential channel 0.0062 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0032 0.0037 0.0076
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0054 0.009 0.2229
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0004 0.0005
Echinococcus granulosus transient receptor potential ion channel A 0.0091 0.018 0.018
Schistosoma mansoni retinoic acid receptor RXR 0.0064 0.0116 0.0116
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0017 0 0.0001
Echinococcus multilocularis lamin dm0 0.0057 0.0097 0.0097
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0372
Plasmodium falciparum heterochromatin protein 1 0.0081 0.0155 0.6236
Echinococcus granulosus zinc finger protein 0.0142 0.0303 0.0303
Entamoeba histolytica hypothetical protein 0.0081 0.0155 0.0216
Loa Loa (eye worm) jmjC domain-containing protein 0.0218 0.0489 0.1012
Loa Loa (eye worm) hypothetical protein 0.0288 0.0658 0.1361
Echinococcus granulosus transient receptor potential gamma protein 0.0094 0.0188 0.0188
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0094 0.0187 0.026
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0276 0.063 0.1835
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0295
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.1455 0.3494 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0064 0.0116 0.0239
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0155 0.0216
Echinococcus granulosus cpg binding protein 0.0075 0.0142 0.0142
Toxoplasma gondii PHD-finger domain-containing protein 0.0017 0.0000073783 0.0002
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0072 0.0072
Brugia malayi MH1 domain containing protein 0.0028 0.0028 0.0058
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0298
Schistosoma mansoni aldehyde dehydrogenase 0.0179 0.0393 0.0393
Mycobacterium tuberculosis Conserved protein 0.0074 0.014 0.0175
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0239
Schistosoma mansoni microtubule-associated protein tau 0.4133 1 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0145 0.0311 0.0643
Echinococcus multilocularis short transient receptor potential channel 6 0.0062 0.0111 0.0111
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0004 0.0095
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0155 0.0216
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0042 0.0087
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0652 0.1544 0.3194
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0017 0 0.0001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0153 0.0331 0.0331
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0113 0.0235 0.0327
Onchocerca volvulus 0.0074 0.014 0.0407
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0153 0.0331 0.0331
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0022 0.0022
Schistosoma mansoni zinc finger protein 0.003 0.0033 0.0033
Brugia malayi E1-E2 ATPase family protein 0.0017 0 0.0001
Leishmania major DNA polymerase kappa, putative 0.0058 0.01 0.2552
Loa Loa (eye worm) PHD-finger family protein 0.0119 0.0249 0.0515
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0033 0.0033
Schistosoma mansoni nuclear hormone receptor 0.0064 0.0116 0.0116
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0 0.0012
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0058 0.01 0.01
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0263 0.0598 0.0598
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0025 0.0025
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0034 0.0042 0.0042
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0025 0.0621
Loa Loa (eye worm) hypothetical protein 0.0096 0.0193 0.0398
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0025 0.0635
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0082 0.017
Brugia malayi mbt repeat family protein 0.0047 0.0072 0.015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0105
Brugia malayi nuclear receptor RXR 0.003 0.0033 0.0068
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0017 0 0.0012
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0014 0.0461
Schistosoma mansoni hypothetical protein 0.0153 0.0331 0.0331
Toxoplasma gondii ABC1 family protein 0.0074 0.014 0.3472
Loa Loa (eye worm) hypothetical protein 0.008 0.0154 0.0319
Schistosoma mansoni myst-related protein 0.002 0.0009 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0182 0.0402 0.0402
Onchocerca volvulus 0.0047 0.0072 0.0211
Echinococcus granulosus intermediate filament protein 0.0057 0.0097 0.0097
Loa Loa (eye worm) MH1 domain-containing protein 0.0051 0.0083 0.0173
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0051 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0017 0.0000073783 0.0000073783
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0031
Plasmodium vivax SNF2 family N-terminal domain containing protein 0.0017 0.0000073783 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0064 0.0116 0.0239
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.014 0.0175
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0081 0.0155 0.6236
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0115 0.3684
Loa Loa (eye worm) hypothetical protein 0.0096 0.0193 0.0398
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.013 0.0275 0.0275
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.014 0.0175
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0017 0 0.0001
Brugia malayi ecdysone receptor 0.003 0.0033 0.0068
Brugia malayi MH2 domain containing protein 0.0023 0.0015 0.0031
Echinococcus multilocularis phd finger protein 10 0.0017 0.0000073783 0.0000073783
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0032 0.0038 0.1205
Schistosoma mansoni aldehyde dehydrogenase 0.0179 0.0393 0.0393
Schistosoma mansoni smad1 5 8 and 0.0051 0.0083 0.0083
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0081 0.0155 0.0155
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0 0.0001
Echinococcus multilocularis geminin 0.121 0.2898 0.2898
Loa Loa (eye worm) PHD-finger family protein 0.0146 0.0313 0.0648
Loa Loa (eye worm) hypothetical protein 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0074 0.014 0.0289
Toxoplasma gondii aldehyde dehydrogenase 0.0179 0.0393 0.9777
Schistosoma mansoni hypothetical protein 0.0049 0.0078 0.0078
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0006 0.0013
Trypanosoma cruzi ISWI complex protein 0.0108 0.0222 0.7129
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0187 0.0414 0.0414
Brugia malayi SET domain containing protein 0.0026 0.0022 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0387 0.0538
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0105
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.014 0.0289
Echinococcus multilocularis muscleblind protein 1 0.2006 0.4834 0.4834
Schistosoma mansoni smad1 5 8 and 0.0051 0.0083 0.0083
Loa Loa (eye worm) E1-E2 ATPase 0.0017 0 0.0001
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0474 0.1112 0.1399
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0202 0.0281
Brugia malayi PHD-finger family protein 0.0119 0.0249 0.0515
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0017 0 0.0014
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0004 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0246 0.0557 0.1152
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0202 0.0281
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0017 0 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.01 0.0287
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0014 0.002
Loa Loa (eye worm) MH2 domain-containing protein 0.0023 0.0015 0.0031
Schistosoma mansoni fyve-containing 0.0017 0.0000073783 0.0000073783
Brugia malayi nuclear hormone receptor 0.0064 0.0116 0.0239
Trypanosoma cruzi cation-transporting ATPase, putative 0.0017 0 0.0016
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0017 0 0.0001
Schistosoma mansoni Replicative DNA helicase 0.0375 0.087 0.087
Mycobacterium ulcerans beta-lactamase 0.0074 0.014 0.0399
Echinococcus multilocularis mothers against decapentaplegic 5 0.0051 0.0083 0.0083
Plasmodium falciparum JmjC domain-containing protein, putative 0.0054 0.009 0.3604
Giardia lamblia Kinase, CMGC MAPK 0.01 0.0202 0.028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0046 0.0058
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0081 0.0155 0.3856
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0054 0.173
Leishmania major DNA polymerase eta, putative 0.0058 0.01 0.2552
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0176 0.0387 0.1128
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0064 0.0116 0.0239
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0375 0.087 0.2489
Onchocerca volvulus 0.0064 0.0116 0.0337
Echinococcus multilocularis jumonji domain containing 1A 0.0054 0.009 0.009
Echinococcus granulosus transcription factor Dp 1 0.0075 0.0142 0.0142
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0086 0.2754
Entamoeba histolytica hypothetical protein 0.0023 0.0014 0.002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0064 0.0116 0.0116
Schistosoma mansoni phd finger protein 0.0017 0.0000073783 0.0000073783
Toxoplasma gondii P-type ATPase4, putative 0.0017 0 0.0012
Echinococcus multilocularis PHD finger protein 14 0.0017 0.0000073783 0.0000073783
Onchocerca volvulus 0.0051 0.0082 0.0239
Schistosoma mansoni chromobox protein 0.0081 0.0155 0.0155
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0034 0.0042 0.0042
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0179 0.0393 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0058 0.01 0.01
Echinococcus granulosus PHD finger protein rhinoceros 0.0119 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.2006 0.4834 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0004 0.0008
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0 0.0012
Echinococcus granulosus smad 0.0051 0.0083 0.0083
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0064 0.0116 0.0116
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0064 0.0116 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0276 0.063 0.0876
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0004 0.0121
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.014 0.0399
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0 0.0001
Echinococcus granulosus TGF beta signal transducer SmadC 0.0051 0.0083 0.0083
Mycobacterium tuberculosis Conserved hypothetical protein 0.0058 0.01 0.0126
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0105
Onchocerca volvulus 0.0017 0 0.0001
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0000073783 0.0000073783
Trypanosoma brucei glucosidase, putative 0.0145 0.0311 1
Echinococcus granulosus lamin 0.0057 0.0097 0.0097
Brugia malayi jmjC domain containing protein 0.0447 0.1046 0.2164
Loa Loa (eye worm) hypothetical protein 0.0054 0.009 0.0187
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0113 0.0235 0.5976
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0033 0.0033
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0036 0.0036
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0062 0.1554
Loa Loa (eye worm) hypothetical protein 0.0074 0.014 0.0289
Echinococcus multilocularis mitogen activated protein kinase 3 0.01 0.0202 0.0202
Schistosoma mansoni polybromo-1 0.0017 0.0001 0.0001
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0145 0.0311 0.773
Brugia malayi PHD-finger family protein 0.0179 0.0395 0.0816
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0081 0.0155 0.3856
Loa Loa (eye worm) hypothetical protein 0.0027 0.0026 0.0053
Brugia malayi M-phase phosphoprotein, mpp8 0.0081 0.0155 0.0321
Schistosoma mansoni zinc finger protein 0.0142 0.0303 0.0303
Mycobacterium ulcerans thymidine phosphorylase 0.1314 0.3152 0.902
Schistosoma mansoni transient receptor potential channel 0.0062 0.0111 0.0111
Echinococcus granulosus lysine specific demethylase 6a 0.0054 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.017
Schistosoma mansoni DNA polymerase eta 0.0058 0.01 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0036 0.1169
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0196 0.0435 0.09
Brugia malayi chromobox protein homolog 3 0.0276 0.063 0.1303
Brugia malayi Nuclear hormone receptor-like 1 0.0064 0.0116 0.0239
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0086 0.2752
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0033 0.0033
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0047 0.0072 0.015
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0004 0.0008
Echinococcus granulosus short transient receptor potential channel 6 0.0062 0.0111 0.0111
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0017 0 0.0016
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.2978 0.7195 1
Schistosoma mansoni cpg binding protein 0.0058 0.0101 0.0101
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0086 0.2754
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0086 0.2129
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.01 0.0208
Leishmania major hypothetical protein, conserved 0.0052 0.0086 0.2177
Brugia malayi mbt repeat family protein 0.0047 0.0072 0.015
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0027 0.0872
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0006 0.0006
Mycobacterium ulcerans hypothetical protein 0.0051 0.0082 0.0234
Brugia malayi Pre-SET motif family protein 0.0182 0.0402 0.0832
Schistosoma mansoni hypothetical protein 0.0081 0.0155 0.0155
Onchocerca volvulus 0.0057 0.0097 0.0282
Brugia malayi nuclear hormone receptor 0.003 0.0033 0.0068
Echinococcus granulosus mothers against decapentaplegic 6 0.0023 0.0015 0.0015
Trypanosoma brucei glycosyl hydrolase-like protein 0.0054 0.009 0.29
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0094 0.0188 0.0389
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0097 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0074 0.014 0.0289
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0435 0.0435
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0017 0 0.0013
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.1314 0.3152 0.3967
Schistosoma mansoni jumonji/arid domain-containing protein 0.0218 0.0489 0.0489
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0064 0.0116 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Brugia malayi jmjC domain containing protein 0.0054 0.009 0.0185
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0072 0.0211
Schistosoma mansoni nuclear receptor 0.003 0.0033 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0003 0.0095
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2978 0.7195 1
Echinococcus multilocularis muscleblind protein 0.2006 0.4834 0.4834
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Onchocerca volvulus Cell death protein 3 homolog 0.0096 0.0193 0.0561
Echinococcus multilocularis TAF3 RNA polymerase II, TATA box binding protein 0.0017 0.0000073783 0.0000073783
Schistosoma mansoni lozenge 0.0056 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0074 0.014 0.0289
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.014 0.0175
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0017 0 0.0001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.014 0.0175
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.014 0.449
Leishmania major proton motive ATPase, putative 0.0017 0 0.0013
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0115 0.3684
Brugia malayi Nuclear hormone receptor E75 0.003 0.0033 0.0068
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0004 0.0154
Echinococcus granulosus histone lysine methyltransferase setb 0.0303 0.0695 0.0695
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0435 0.0435
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0025 0.0804
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0022 0.0013 0.0013
Mycobacterium leprae conserved hypothetical protein 0.0074 0.014 0.0399
Leishmania major importin beta-1 subunit, putative 0.0023 0.0014 0.0365
Loa Loa (eye worm) hypothetical protein 0.0177 0.0389 0.0805
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0064 0.0116 0.0239
Echinococcus multilocularis transient receptor potential ion channel A 0.0091 0.018 0.018
Echinococcus multilocularis chromobox protein 2 0.0081 0.0155 0.0155
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.0544 0.0544
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.01 0.3228
Schistosoma mansoni hypothetical protein 0.008 0.0154 0.0154
Loa Loa (eye worm) runx1 0.0056 0.0094 0.0195
Echinococcus granulosus Chromo domain 0.0081 0.0155 0.0155
Echinococcus granulosus apoptotic protease activating factor 1 0.0096 0.0193 0.0193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0064 0.0116 0.0239
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0019 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0064 0.0116 0.0239
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0113 0.0235 0.7559
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0187 0.0414 0.0414
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.01 0.3227
Schistosoma mansoni hepatitis B virus X associated protein hbxa 0.0017 0.0000073783 0.0000073783
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0182 0.0402 1
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0017 0 0.0001
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0447 0.1046 0.1046
Echinococcus granulosus phd finger protein 12 0.0017 0.0000073783 0.0000073783
Brugia malayi nuclear receptor RXR 0.0034 0.0042 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0611 0.0849
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0082 0.0103
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0239
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.01 0.0202 0.5029
Echinococcus multilocularis PHD finger protein rhinoceros 0.0119 0.0249 0.0249
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0033 0.0068
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0036 0.0046
Schistosoma mansoni hypothetical protein 0.0146 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0048
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0254 0.0575 0.0575
Brugia malayi polk-prov protein 0.0018 0.0003 0.0006
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0054 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0017 0 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0202 0.0281
Echinococcus multilocularis short transient receptor potential channel 6 0.0062 0.0111 0.0111
Schistosoma mansoni smad1 5 8 and 0.0051 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0145 0.031 0.0642
Leishmania major hypothetical protein, conserved 0.0108 0.0222 0.5636
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0105
Brugia malayi MH1 domain containing protein 0.0051 0.0083 0.0173
Loa Loa (eye worm) hypothetical protein 0.0113 0.0235 0.0486
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0033 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Echinococcus multilocularis dna polymerase kappa 0.0058 0.01 0.01
Schistosoma mansoni smad 0.0051 0.0083 0.0083
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0119 0.0249 0.0249
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.013 0.0275 0.8861
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.01 0.3228
Onchocerca volvulus 0.0263 0.0598 0.1742
Echinococcus granulosus lamin dm0 0.0057 0.0097 0.0097
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0033 0.0068
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0072 0.0072
Brugia malayi F/Y-rich N-terminus family protein 0.0078 0.0149 0.0308
Trypanosoma brucei cation-transporting ATPase, putative 0.0017 0 0.0014
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0038 0.0051 0.058
Echinococcus granulosus PHD and RING finger domain containing protein 1 0.0017 0.0000073783 0.0000073783
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0036 0.0883
Schistosoma mansoni methyl-cpg binding protein mbd 0.012 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0105
Echinococcus multilocularis mothers against decapentaplegic 2 0.0023 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0017 0.0000073783 0.0000073783
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.014 0.0194
Schistosoma mansoni hypothetical protein 0.0119 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0216 0.0485 0.1004
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0017 0 0.0013
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0036 0.0925
Echinococcus granulosus ecdysone induced protein 78C 0.0064 0.0116 0.0116
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0064 0.0116 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Brugia malayi SET domain containing protein 0.009 0.0177 0.0366
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0004 0.0005
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0017 0 0.0001
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0006 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0155 0.0216
Entamoeba histolytica hypothetical protein 0.0153 0.0331 0.046
Brugia malayi Heterochromatin protein 1 0.0493 0.1156 0.2391
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0016 0.0016
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0009 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.009 0.0125
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0086 0.3442
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0036 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0064 0.0116 0.0239
Echinococcus granulosus neuropeptide receptor A26 0.045 0.1052 0.1052
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0013 0.0013
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0019
Schistosoma mansoni bromodomain containing protein 0.0034 0.0041 0.0041
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0064 0.0116 0.0239
Trypanosoma cruzi ISWI complex protein 0.0108 0.0222 0.7129
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0017 0 0.0001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0097 0.02
Echinococcus granulosus dna polymerase kappa 0.0058 0.01 0.01
Schistosoma mansoni hypothetical protein 0.121 0.2898 0.2898
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0113 0.0235 0.0326
Schistosoma mansoni cpg binding protein 0.0075 0.0142 0.0142
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0 0.0001
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0 0.0016
Echinococcus multilocularis chromobox protein 1 0.0493 0.1156 0.1156
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0004 0.0009
Schistosoma mansoni jumonji domain containing protein 0.0054 0.009 0.009
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0017 0 0.0001
Leishmania major cytochrome p450-like protein 0.0019 0.0004 0.0109
Loa Loa (eye worm) hypothetical protein 0.0081 0.0155 0.0321
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2978 0.7195 1
Giardia lamblia PHD finger protein 15 0.0119 0.0249 0.0345
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0051 0.0083 0.0083
Brugia malayi MH2 domain containing protein 0.0051 0.0083 0.0173
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0017 0 0.0001
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0004 0.0136
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0179 0.0393 0.0393
Trichomonas vaginalis ran, putative 0.0021 0.0009 0.0013
Brugia malayi MH1 domain containing protein 0.0028 0.0028 0.0058
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0276 0.063 0.1303
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0 0.0001
Trypanosoma cruzi proton motive ATPase 1, putative 0.0017 0 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.041 0.057
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0003 0.0095
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0082 0.2085
Schistosoma mansoni zinc finger protein 0.0108 0.0222 0.0222
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0003 0.0095
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0082 0.2085
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0081 0.2615
Schistosoma mansoni hypothetical protein 0.008 0.0154 0.0154
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0036 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0064 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0074 0.014 0.0289
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0042 0.0062 0.2512
Trichomonas vaginalis conserved hypothetical protein 0.0195 0.0434 0.0603
Echinococcus granulosus mothers against decapentaplegic 2 0.0023 0.0015 0.0015
Entamoeba histolytica recQ family helicase, putative 0.0025 0.002 0.0028
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0019 0.0005 0.0005
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.013 0.0275 0.0383
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0087
Loa Loa (eye worm) MH2 domain-containing protein 0.0751 0.1783 0.3689
Schistosoma mansoni jumonji domain containing protein 0.0367 0.0851 0.0851
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0057 0.1817
Schistosoma mansoni flap endonuclease-1 0.0024 0.0019 0.0019
Trypanosoma brucei P-type H+-ATPase, putative 0.0017 0 0.0014
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0072 0.0072
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0036 0.0036
Toxoplasma gondii P-type ATPase PMA1 0.0017 0 0.0012
Loa Loa (eye worm) hypothetical protein 0.0303 0.0695 0.1437
Echinococcus multilocularis Protein lozenge 0.0056 0.0094 0.0094
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.009 0.0125
Toxoplasma gondii PHD-finger domain-containing protein 0.0039 0.0054 0.1339
Schistosoma mansoni nuclear hormone receptor 0.003 0.0033 0.0033
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0017 0 0.0001
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.014 0.0175
Brugia malayi Calcitonin receptor-like protein seb-1 0.0254 0.0575 0.119
Brugia malayi MH2 domain containing protein 0.0751 0.1783 0.3689
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0064 0.0116 0.0116
Echinococcus multilocularis chromobox protein 1 0.0493 0.1156 0.1156
Trypanosoma brucei P-type H+-ATPase, putative 0.0017 0 0.0014
Onchocerca volvulus Bile acid receptor homolog 0.0064 0.0116 0.0337
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0094 0.0187 0.026
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0081 0.0155 0.0321
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0033 0.0033
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0027 0.0676
Schistosoma mansoni jumonji/arid domain-containing protein 0.0218 0.0489 0.0489
Plasmodium vivax heterochromatin protein 1, putative 0.0081 0.0155 0.3856
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0003 0.0095
Entamoeba histolytica hypothetical protein 0.0081 0.0155 0.0216
Brugia malayi Cytochrome P450 family protein 0.0028 0.0028 0.0057
Schistosoma mansoni nuclear receptor 0.003 0.0033 0.0033
Echinococcus multilocularis ubiquitin specific protease 41 0.0113 0.0235 0.0235
Schistosoma mansoni survival motor neuron protein 0.0049 0.0078 0.0078
Echinococcus granulosus muscleblind protein 0.2006 0.4834 0.4834
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0003 0.0095
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0036 0.0036
Trypanosoma cruzi DNA repair protein, putative 0.0032 0.0038 0.1207
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0101 0.325
Brugia malayi hypothetical protein 0.0153 0.0331 0.0684
Echinococcus granulosus Zinc finger DBF type 0.0017 0.0000073783 0.0000073783
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0172 0.0239
Trypanosoma cruzi DNA polymerase eta, putative 0.0018 0.0003 0.0098
Onchocerca volvulus 0.0081 0.0155 0.0452
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0081 0.0155 0.0155
Brugia malayi Cytochrome P450 family protein 0.0019 0.0004 0.0009
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0051 0.0082 0.0234
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.01 0.3228
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0 0.0001
Loa Loa (eye worm) CHromoDomain protein family member 0.0097 0.0196 0.0405
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0064 0.0116 0.0116
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.0051 0.0145
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0097 0.02
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0393 0.1125
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0009 0.023
Brugia malayi hypothetical protein 0.0034 0.0042 0.0087
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0004 0.0005
Schistosoma mansoni nuclear hormone receptor 0.003 0.0033 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.041 0.057
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.007 0.013 0.013
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0039 0.0054 0.1339
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0081 0.0155 0.0155
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Trichomonas vaginalis conserved hypothetical protein 0.0276 0.063 0.0876
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.0685 0.1416
Schistosoma mansoni dpf3 0.0017 0.0000073783 0.0000073783
Plasmodium falciparum EELM2 domain-containing protein, putative 0.0017 0.0000073783 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0303 0.0695 0.0695
Echinococcus multilocularis GPCR, family 2 0.008 0.0154 0.0154
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2978 0.7195 1
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0074 0.014 0.0289
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0119 0.0249 0.0515
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0064 0.0116 0.0116
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0311 0.0432
Brugia malayi steroid hormone receptor 0.0064 0.0116 0.0239
Loa Loa (eye worm) hypothetical protein 0.0254 0.0575 0.119
Onchocerca volvulus 0.0444 0.1037 0.3021
Echinococcus granulosus bloom syndrome protein 0.0047 0.0073 0.0073
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0081 0.0155 0.0216
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0097 0.0196 0.0196
Onchocerca volvulus 0.003 0.0033 0.0096
Brugia malayi Bromodomain containing protein 0.027 0.0616 0.1275
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0082 0.017
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.009 0.0125
Toxoplasma gondii exonuclease III APE 0.0018 0.0004 0.0095
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0088 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0064 0.0116 0.0239
Brugia malayi Cytochrome P450 family protein 0.0019 0.0004 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0195 0.0434 0.0603
Trichomonas vaginalis chromobox protein, putative 0.0493 0.1156 0.1606
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0094 0.0187 0.026
Brugia malayi hypothetical protein 0.0034 0.0041 0.0084
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0026 0.0026
Schistosoma mansoni transient receptor potential channel 4 0.0094 0.0188 0.0188
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0179 0.0393 0.0495
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0387 0.0538
Leishmania major cathepsin L-like protease 0.0064 0.0115 0.2913
Loa Loa (eye worm) hypothetical protein 0.0081 0.0155 0.0321
Brugia malayi beta-lactamase 0.0074 0.014 0.0289
Echinococcus multilocularis polybromo 1 0.0017 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0287 0.0656 0.0656
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0017 0 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0082 0.0234
Loa Loa (eye worm) hypothetical protein 0.0056 0.0095 0.0196
Loa Loa (eye worm) calcium ATPase 0.0017 0 0.0001
Trichomonas vaginalis set domain proteins, putative 0.143 0.3433 0.4772
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.002 0.0515
Schistosoma mansoni myst-related protein 0.002 0.0009 0.0009
Schistosoma mansoni chromobox protein 0.0493 0.1156 0.1156
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0033 0.0068
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0073 0.0102
Echinococcus multilocularis mitogen activated protein kinase 0.01 0.0202 0.0202
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0462 0.1082 0.2238
Echinococcus granulosus neutral alpha glucosidase AB 0.0145 0.0311 0.0311
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0254 0.0575 0.0575
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0000073783 0.0002
Trypanosoma cruzi P-type H+-ATPase, putative 0.0017 0 0.0016
Schistosoma mansoni DNA helicase recq1 0.0019 0.0006 0.0006
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0025 0.0621
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0054 0.009 0.2902
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0013 0.0013
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.017
Loa Loa (eye worm) DR-78 0.003 0.0033 0.0068
Schistosoma mansoni cpg binding protein 0.0075 0.0142 0.0142
Echinococcus granulosus GPCR family 2 0.008 0.0154 0.0154
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0017 0 0.0016
Brugia malayi MH1 domain containing protein 0.0051 0.0083 0.0173
Echinococcus granulosus jumonji domain containing 1A 0.0054 0.009 0.009
Plasmodium vivax cation transporting ATPase, putative 0.0017 0 0.0012
Brugia malayi Importin beta-1 subunit 0.0028 0.0027 0.0056
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0025 0.0801
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0081 0.0155 0.0216
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0 0.0001
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0375 0.087 0.2489
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0003 0.0076
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0017 0 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0311 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0179 0.0393 0.0393
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0113 0.0235 0.0486
Echinococcus granulosus jumonji domain containing protein 0.0166 0.0362 0.0362
Entamoeba histolytica hypothetical protein 0.0153 0.0331 0.046
Toxoplasma gondii histone lysine methyltransferase SET1 0.0135 0.0287 0.7132
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0 0.0001
Echinococcus multilocularis thymidine phosphorylase 0.1314 0.3152 0.3152
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0027 0.0027
Loa Loa (eye worm) glutaminase 2 0.0541 0.1273 0.2633
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0311 0.0432
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0056
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0017 0 0.0001
Onchocerca volvulus 0.0081 0.0155 0.0452
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0064 0.0116 0.0239
Echinococcus multilocularis caspase 2 0.0096 0.0193 0.0193
Onchocerca volvulus 0.003 0.0033 0.0096
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0311 0.0432
Schistosoma mansoni hypothetical protein 0.008 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0006
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0064 0.0116 0.0116
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0425 0.0991 0.0991
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.01 0.0202 0.6506
Leishmania major calcium-translocating P-type ATPase 0.0017 0 0.0013
Echinococcus granulosus chromobox protein 1 0.0493 0.1156 0.1156
Echinococcus granulosus polybromo 1 0.0017 0.0001 0.0001
Echinococcus multilocularis microtubule associated protein 2 0.4133 1 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0155 0.0321
Echinococcus multilocularis thyroid hormone receptor alpha 0.0064 0.0116 0.0116
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0082 0.0234
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0022 0.0022
Schistosoma mansoni DNA helicase recq5 0.0019 0.0006 0.0006
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0003 0.0098
Echinococcus granulosus TAF3 RNA polymerase II TATA box binding protein 0.0017 0.0000073783 0.0000073783
Onchocerca volvulus 0.0026 0.0022 0.0064
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0058 0.01 0.0139
Schistosoma mansoni glutaminase 0.0541 0.1273 0.1273
Plasmodium falciparum copper-transporting ATPase 0.0017 0 0.002
Entamoeba histolytica hypothetical protein 0.0081 0.0155 0.0216
Onchocerca volvulus 0.0074 0.014 0.0407
Leishmania major cathepsin L-like protease 0.0064 0.0115 0.2913
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0051 0.0082 0.0103
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0054 0.009 0.2229
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.01 0.0202 0.5144
Brugia malayi Bromodomain containing protein 0.0136 0.0289 0.0599
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0054 0.173
Schistosoma mansoni Smad4 0.0051 0.0083 0.0083
Schistosoma mansoni bromodomain containing protein 0.045 0.1053 0.1053
Echinococcus multilocularis dnaJ subfamily B 0.083 0.1975 0.1975
Plasmodium falciparum zinc finger protein, putative 0.002 0.0009 0.035
Brugia malayi isocitrate dehydrogenase 0.0032 0.0036 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0387 0.0538
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0154 0.0154
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0177 0.0389 0.0805
Echinococcus multilocularis lysosomal alpha glucosidase 0.0652 0.1544 0.1544
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.009 0.0125
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0145 0.0311 0.0432
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0447 0.1046 0.1046
Echinococcus multilocularis lysine specific demethylase 5A 0.0201 0.0448 0.0448
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Brugia malayi Na,K-ATPase alpha subunit 0.0017 0 0.0001
Echinococcus multilocularis uro adherence factor A 0.0017 0.0000073783 0.0000073783
Schistosoma mansoni Smad4 0.0023 0.0015 0.0015
Giardia lamblia DNA damage repair protein 0.0018 0.0003 0.0004
Brugia malayi RNA, U transporter 1 0.008 0.0152 0.0315
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0221 0.0497 0.1028
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0082 0.0234
Brugia malayi jmjC domain containing protein 0.0054 0.009 0.0185
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.01 0.0126
Loa Loa (eye worm) nuclear factor I 0.0028 0.0028 0.0058
Brugia malayi Protein cec-1. 0.0081 0.0155 0.0321
Schistosoma mansoni PHD zinc finger protein XAP135-related 0.0017 0.0000073783 0.0000073783
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0393 0.1125
Entamoeba histolytica hypothetical protein 0.0153 0.0331 0.046
Echinococcus granulosus short transient receptor potential channel 6 0.0062 0.0111 0.0111
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.01 0.0287
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0311 0.0432
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0239
Brugia malayi AF-10 protein 0.0039 0.0054 0.0111
Schistosoma mansoni eyes absent homolog 0.0177 0.0389 0.0389
Schistosoma mansoni hypothetical protein 0.0017 0.0000073783 0.0000073783
Plasmodium vivax calcium-transporting ATPase, putative 0.0017 0 0.0012
Brugia malayi tailless protein 0.003 0.0033 0.0068
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0182 0.0402 0.0402
Toxoplasma gondii SWI2/SNF2-containing PHD finger protein 0.0017 0.0000073783 0.0002
Schistosoma mansoni hypothetical protein 0.0096 0.0193 0.0193
Mycobacterium ulcerans recombinase A 0.0105 0.0214 0.0611
Loa Loa (eye worm) hypothetical protein 0.0017 0 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0435 0.0435
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0078 0.0162
Schistosoma mansoni ran 0.0021 0.0009 0.0009
Plasmodium vivax SET domain protein, putative 0.0182 0.0402 1
Schistosoma mansoni phd/f-box containing protein 0.0054 0.009 0.009
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0162 0.0354 0.0354
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0017 0 0.0001
Giardia lamblia DINP protein human, muc B family 0.0058 0.01 0.0139
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0042 0.0042
Brugia malayi hypothetical protein 0.0081 0.0155 0.0321
Loa Loa (eye worm) glutaminase 0.0541 0.1273 0.2633
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.0116 0.0116
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0051 0.0064
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0013
Trypanosoma cruzi copper-transporting ATPase, putative 0.0017 0 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0611 0.0849
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0113 0.0235 0.0235
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0004 0.0004
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0082 0.017
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0006 0.0256
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0006 0.0158
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0033 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0064 0.0116 0.0239
Echinococcus multilocularis phd:f box containing protein 0.0054 0.009 0.009
Schistosoma mansoni RAR-like nuclear receptor 0.0064 0.0116 0.0116
Schistosoma mansoni methyl-cpg binding protein mbd 0.012 0.0252 0.0252
Schistosoma mansoni SET domain protein 0.0042 0.0061 0.0061
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0004 0.0138
Leishmania major P-type H -ATPase, putative 0.0017 0 0.0013
Loa Loa (eye worm) hypothetical protein 0.0081 0.0155 0.0321
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0154 0.0154
Toxoplasma gondii PHD-finger domain-containing protein 0.0119 0.0249 0.6184
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0155 0.0216
Loa Loa (eye worm) Smad1 0.0051 0.0083 0.0173
Schistosoma mansoni thyroid hormone receptor 0.0064 0.0116 0.0116
Onchocerca volvulus 0.0216 0.0485 0.1413
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0202 0.0281
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0004 0.0012
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0113 0.0235 0.7559
Toxoplasma gondii AP2 domain transcription factor AP2VIIa-7 0.0017 0.0000073783 0.0002
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.006 0.2394
Echinococcus multilocularis neutral alpha glucosidase AB 0.0145 0.0311 0.0311
Schistosoma mansoni Smad4 0.0023 0.0015 0.0015
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.014 0.0194
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0073 0.0152
Trichomonas vaginalis maltase-glucoamylase, putative 0.0054 0.009 0.0125
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0059 0.0103 0.0213
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0064 0.0116 0.0116
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.0051 0.2049
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0 0.0001
Echinococcus granulosus phd:f box containing protein 0.0054 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0017 0 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0064 0.0116 0.0239
Trichomonas vaginalis chromobox protein, putative 0.0297 0.0681 0.0946
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0006 0.0013
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0017 0 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.01 0.3228
Schistosoma mansoni hypothetical protein 0.0023 0.0016 0.0016
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0105 0.0214 0.0611
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0009 0.0009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0064 0.0116 0.0116
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0023 0.0015 0.0043
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0033 0.0068
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0113 0.0235 0.0235
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0035 0.0044 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0042 0.0087
Echinococcus multilocularis transcription factor Dp 1 0.0075 0.0142 0.0142
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0003 0.0076
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0088 0.0088
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0094 0.0187 0.026
Schistosoma mansoni phd finger protein 0.0017 0.0000073783 0.0000073783
Schistosoma mansoni lamin 0.0057 0.0097 0.0097
Echinococcus granulosus lysine specific demethylase 5B 0.0017 0.0000073783 0.0000073783
Brugia malayi hypothetical protein 0.0096 0.0193 0.0398
Onchocerca volvulus 0.0049 0.0078 0.0229
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0000073783 0.0000073783
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.014 0.0175
Schistosoma mansoni hypothetical protein 0.121 0.2898 0.2898
Brugia malayi hypothetical protein 0.0052 0.0086 0.0177
Mycobacterium ulcerans hypothetical protein 0.0074 0.014 0.0399
Brugia malayi E1-E2 ATPase family protein 0.0017 0 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0054 0.009 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Loa Loa (eye worm) heterochromatin protein 1 0.0493 0.1156 0.2391
Loa Loa (eye worm) helicase 0.0081 0.0155 0.0321
Schistosoma mansoni steroid hormone receptor ad4bp 0.0064 0.0116 0.0116
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0017 0 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0094 0.0187 0.026
Loa Loa (eye worm) hypothetical protein 0.0052 0.0086 0.0177
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0009 0.023
Echinococcus multilocularis smad 0.0051 0.0083 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0046 0.0058
Loa Loa (eye worm) hypothetical protein 0.0058 0.01 0.0208
Entamoeba histolytica deoxycytidyl transferase, putative 0.0058 0.01 0.0139
Loa Loa (eye worm) hypothetical protein 0.0304 0.0699 0.1446
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0081 0.0155 0.0321
Loa Loa (eye worm) hypothetical protein 0.0173 0.038 0.0787
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0046 0.0058
Echinococcus multilocularis lamin 0.0057 0.0097 0.0097
Echinococcus multilocularis JmjC domain containing protein 4 0.0054 0.009 0.009
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2471 0.5962 0.5962
Echinococcus multilocularis jumonji domain containing protein 0.0166 0.0362 0.0362
Echinococcus granulosus PHD finger protein 14 0.0017 0.0000073783 0.0000073783
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0072 0.0072
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.014 0.014
Mycobacterium tuberculosis Conserved protein 0.0074 0.014 0.0175
Echinococcus multilocularis lysine specific demethylase 6a 0.0054 0.009 0.009
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0017 0 0.0001
Brugia malayi intermediate filament protein 0.0057 0.0097 0.02
Echinococcus granulosus thymidine phosphorylase 0.1314 0.3152 0.3152
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.013 0.0275 0.057
Trichomonas vaginalis maltase-glucoamylase, putative 0.0145 0.0311 0.0432
Echinococcus granulosus mothers against decapentaplegic 5 0.0051 0.0083 0.0083
Plasmodium vivax importin-beta 2, putative 0.0028 0.0027 0.0676
Trypanosoma brucei unspecified product 0.0058 0.01 0.3227
Schistosoma mansoni chromobox protein 0.0493 0.1156 0.1156
Echinococcus granulosus fetal alzheimer antigen falz 0.0162 0.0354 0.0354
Plasmodium vivax hypothetical protein, conserved 0.0074 0.014 0.3472
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0048
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0004 0.0009
Brugia malayi beta-lactamase family protein 0.0074 0.014 0.0289
Echinococcus multilocularis snurportin 1 0.0299 0.0685 0.0685
Plasmodium vivax SET domain containing protein 0.0026 0.0022 0.0542
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0064 0.0116 0.0239
Chlamydia trachomatis recombinase RecA 0.0105 0.0214 0.245
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0094 0.0187 0.026
Loa Loa (eye worm) hypothetical protein 0.0081 0.0155 0.0321
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0019
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0064 0.0116 0.0337
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.002 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0094 0.0187 0.026
Brugia malayi Nuclear hormone receptor E75 0.003 0.0033 0.0068
Schistosoma mansoni transcription factor LCR-F1 0.0153 0.0331 0.0331
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0051 0.0082 0.0234
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2978 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0088 0.0182
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0003 0.0098
Echinococcus granulosus importin subunit beta 1 0.0028 0.0027 0.0027
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0113 0.0235 0.0235
Trichomonas vaginalis glutaminase, putative 0.0541 0.1273 0.1769
Leishmania major hypothetical protein, conserved 0.0054 0.009 0.228
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2978 0.7195 1
Echinococcus multilocularis musashi 0.0057 0.0097 0.0097
Echinococcus multilocularis transcription factor eb 0.0462 0.1082 0.1082
Onchocerca volvulus Protein ultraspiracle homolog 0.0064 0.0116 0.0337
Schistosoma mansoni hypothetical protein 0.083 0.1975 0.1975
Trichomonas vaginalis chromobox protein, putative 0.0493 0.1156 0.1606
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.01 0.3228
Echinococcus multilocularis PHD and RING finger domain containing protein 1 0.0017 0.0000073783 0.0000073783
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.01 0.2552
Entamoeba histolytica Ran family GTPase 0.0021 0.0009 0.0013
Echinococcus multilocularis remodeling and spacing factor 1 0.0017 0.0000073783 0.0000073783
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0064 0.0116 0.0116
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0028 0.0057
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0017 0 0.0001
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0054 0.009 0.0125
Brugia malayi MAP kinase sur-1 0.01 0.0202 0.0418
Trichomonas vaginalis sucrase-isomaltase, putative 0.0145 0.0311 0.0432
Brugia malayi Associated with TFs and helicases family protein 0.0081 0.0155 0.0321
Schistosoma mansoni lamin 0.0057 0.0097 0.0097
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.014 0.0194
Echinococcus multilocularis histone acetyltransferase myst3 0.0017 0.0000073783 0.0000073783
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.038 0.0787
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.01 0.3227
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.01 0.0202 0.6506
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0058
Schistosoma mansoni ap endonuclease 0.0018 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0074 0.014 0.3551
Brugia malayi Bromodomain containing protein 0.0533 0.1253 0.2593
Mycobacterium ulcerans lipase LipD 0.0074 0.014 0.0399
Loa Loa (eye worm) hypothetical protein 0.0444 0.1037 0.2146
Brugia malayi Glycosyl hydrolases family 31 protein 0.0652 0.1544 0.3194
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0017 0 0.0001
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0017 0 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0046 0.0058
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0 0.0012
Brugia malayi Cell death protein 3 precursor 0.0096 0.0193 0.0398
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0054 0.009 0.0125
Mycobacterium leprae Probable lipase LipE 0.0074 0.014 0.0399
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0173 0.038 0.038
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0033 0.0068
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0387 0.0538
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0003 0.0095
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0033 0.0033
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.013 0.0275 0.0275
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0027 0.0872
Onchocerca volvulus Glucosylceramidase homolog 0.0176 0.0387 0.1127
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0387 0.0538
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0239
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0154 0.0319
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0239
Leishmania major cathepsin L-like protease 0.0064 0.0115 0.2913
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2978 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0068
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.014 0.014
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.014 0.0194
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0303 0.0695 0.0695
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0054 0.009 0.2883
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0004 0.0004
Echinococcus multilocularis ecdysone induced protein 78C 0.0064 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.2006 0.4834 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0064 0.0116 0.0116
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0014 0.002
Echinococcus granulosus dna polymerase eta 0.0058 0.01 0.01
Loa Loa (eye worm) MH2 domain-containing protein 0.0051 0.0083 0.0173
Echinococcus granulosus caspase 2 0.0096 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0499 0.1172 0.2425
Loa Loa (eye worm) hypothetical protein 0.0017 0 0.0001
Schistosoma mansoni alpha-glucosidase 0.0561 0.1323 0.1323
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.1455 0.3494 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0119 0.0249 0.6184
Loa Loa (eye worm) hypothetical protein 0.0054 0.009 0.0185
Plasmodium vivax JmjC domain containing protein 0.0054 0.009 0.2229
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.014 0.0175
Echinococcus multilocularis neuropeptide s receptor 0.045 0.1052 0.1052
Treponema pallidum fructose-bisphosphate aldolase 0.2978 0.7195 1
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.014 0.4491
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0017 0 0.0012
Schistosoma mansoni caspase-7 (C14 family) 0.0096 0.0193 0.0193
Brugia malayi conserved hypotetical protein 0.003 0.0033 0.0068
Onchocerca volvulus Alhambra homolog 0.0119 0.0249 0.0724
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.0116 0.0116
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0073 0.0102
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0017 0 0.0012
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0017 0 0.0001
Brugia malayi hypothetical protein 0.0444 0.1037 0.2146
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0033 0.0068
Echinococcus granulosus mitogen activated protein kinase 0.01 0.0202 0.0202
Mycobacterium leprae Conserved hypothetical protein 0.1105 0.2644 0.7567
Brugia malayi Smad1 0.0051 0.0083 0.0173
Echinococcus granulosus JmjC domain containing protein 4 0.0054 0.009 0.009
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0036 0.0904
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.01 0.0202 0.0418
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0082 0.2085
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.0116 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0611 0.0849
Trichomonas vaginalis hypothetical protein 0.0081 0.0155 0.0216
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.2978 0.7195 1
Brugia malayi ecdysteroid receptor 0.0064 0.0116 0.0239
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.009 0.0125
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0036 0.0075
Brugia malayi Transient-receptor-potential like protein 0.0035 0.0044 0.0092
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.0202 0.6506
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.013 0.0275 0.8861
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0057 0.1817
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.014 0.0289
Giardia lamblia Fructose-bisphosphate aldolase 0.2978 0.7195 1
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0054 0.009 0.2902
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0033 0.0068
Schistosoma mansoni hypothetical protein 0.0017 0.0000073783 0.0000073783
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0239
Echinococcus granulosus transcription factor eb 0.0462 0.1082 0.1082
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.0116 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0115 0.3682
Echinococcus granulosus remodeling and spacing factor 1 0.0017 0.0000073783 0.0000073783
Onchocerca volvulus 0.0096 0.0193 0.0561
Echinococcus multilocularis phd finger protein 12 0.0017 0.0000073783 0.0000073783
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0003 0.0098
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.01 0.0202 0.6505
Leishmania major glycosyl hydrolase-like protein 0.0054 0.009 0.2294

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 115 nM The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) expressing LacZ (beta-galactosidase). ChEMBL. 10395490
IC50 (functional) = 115 nM The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) expressing LacZ (beta-galactosidase). ChEMBL. 10395490
IC50 (functional) = 177 nM The compound was tested for extracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of stCPG2 prodrug ChEMBL. 10395490
IC50 (functional) = 177 nM The compound was tested for extracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of stCPG2 prodrug ChEMBL. 10395490
IC50 (functional) = 405 nM The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of CPG2 prodrug ChEMBL. 10395490
IC50 (functional) = 405 nM The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of CPG2 prodrug ChEMBL. 10395490
Ratio (functional) = 0.3 Ratio of the extracellular cytotoxicities against MDA MB 361(mammary carcinoma cell line) exressing LacZ and carboxypeptidase stCPG2 of the prodrug. ChEMBL. 10395490
Ratio (functional) = 0.7 Ratio of the extracellular cytotoxicities against MDA MB 361(mammary carcinoma cell line) exressing LacZ and carboxypeptidase stCPG2 of the prodrug. ChEMBL. 10395490
Ratio (functional) = 6.8 Ratio of the intracellular cytotoxicities against MDA MB 361(mammary carcinoma cell line) expressing LacZ (beta-galactosidase). between prodrug and drug. ChEMBL. 10395490
T1/2 (ADMET) = 132.4 min Half life period of the compound in the presence of CPG2 (carboxypeptidase) enzyme ChEMBL. 10395490
T1/2 (ADMET) = 1482 min Half life period of the compound in the absence of CPG2 (carboxypeptidase) enzyme ChEMBL. 10395490

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 10395490

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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