Detailed information for compound 1368837

Basic information

Technical information
  • TDR Targets ID: 1368837
  • Name: N-[4-[(2,4-dichlorobenzoyl)amino]phenyl]-1,3- benzodioxole-5-carboxamide
  • MW: 429.253 | Formula: C21H14Cl2N2O4
  • H donors: 2 H acceptors: 2 LogP: 4.66 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(c(c1)Cl)C(=O)Nc1ccc(cc1)NC(=O)c1ccc2c(c1)OCO2
  • InChi: 1S/C21H14Cl2N2O4/c22-13-2-7-16(17(23)10-13)21(27)25-15-5-3-14(4-6-15)24-20(26)12-1-8-18-19(9-12)29-11-28-18/h1-10H,11H2,(H,24,26)(H,25,27)
  • InChiKey: PYORKDUVQGRLLF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-[[(2,4-dichlorophenyl)-oxomethyl]amino]phenyl]-1,3-benzodioxole-5-carboxamide
  • N-[4-[(2,4-dichlorophenyl)carbonylamino]phenyl]-1,3-benzodioxole-5-carboxamide
  • BAS 07437864
  • TULIP021476

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0086
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0029 0.0137 0.1087
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0152 0.0148
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.003 0.0143 0.0138
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0201 0.0511
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0065 0.0428 0.2254
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0058 0.0371 0.0366
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0031 0.0152 0.0142
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0152 0.0142
Loa Loa (eye worm) hypothetical protein 0.0079 0.0542 0.0538
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0349 0.0339
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0037 0.0202 0.0198
Echinococcus multilocularis lamin dm0 0.0056 0.0357 0.0352
Brugia malayi nuclear hormone receptor family member nhr-6 0.0037 0.0202 0.0199
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0009 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0024 0.0062
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.124 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0152 0.0142
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0349 0.0339
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0412 0.0408
Loa Loa (eye worm) hypothetical protein 0.003 0.0147 0.0142
Echinococcus multilocularis 0.0043 0.025 0.0245
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.004 0.0226 0.0222
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0024 0.0091 0.0232
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0392 0.0387
Brugia malayi nuclear receptor NHR-67 0.0037 0.0202 0.0199
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.0082 0.046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2351 0.5985
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0079 0.0542 0.0539
Echinococcus multilocularis disks large 1 0.004 0.0228 0.0223
Echinococcus multilocularis MAGUK p55 subfamily 0.0043 0.025 0.0245
Brugia malayi neuropeptide F receptor 0.0031 0.0152 0.0149
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0143 0.1064 0.106
Echinococcus granulosus single minded 2 0.0037 0.0201 0.0196
Brugia malayi Pre-SET motif family protein 0.0063 0.0412 0.0408
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0029 0.0073
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0276 0.0272
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0152 0.0148
Brugia malayi SET domain containing protein 0.0015 0.0019 0.0016
Mycobacterium leprae Probable guanylate kinase Gmk (GMP kinase). 0.004 0.0228 0.204
Schistosoma mansoni eyes absent homolog 0.0091 0.0638 0.0629
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0268 0.2082 0.2078
Echinococcus granulosus BC026374 protein S09 family 0.0024 0.0091 0.0086
Echinococcus granulosus thyroid hormone receptor alpha 0.0037 0.0202 0.0198
Toxoplasma gondii cytochrome p450 superfamily protein 0.0029 0.0137 0.0382
Echinococcus granulosus hypothetical protein 0.0058 0.0371 0.0366
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0095 0.0167
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0144 0.014
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0058 0.0371 0.0361
Schistosoma mansoni alpha-1 adrenergic receptor 0.0031 0.0152 0.0142
Loa Loa (eye worm) hypothetical protein 0.0016 0.003 0.0026
Echinococcus granulosus lamin dm0 0.0056 0.0357 0.0352
Loa Loa (eye worm) hypothetical protein 0.0043 0.025 0.0245
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0058 0.0371 0.0361
Echinococcus granulosus ecdysone induced protein 78C 0.0079 0.0542 0.0538
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0062 0.0402 0.0398
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0412 0.0402
Brugia malayi tailless protein 0.0037 0.0202 0.0199
Schistosoma mansoni axis inhibition protein axin 0.002 0.006 0.005
Loa Loa (eye worm) hypothetical protein 0.0079 0.0542 0.0538
Echinococcus granulosus neuropeptide receptor A26 0.0031 0.0152 0.0148
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.0412 0.217
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0055
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0024 0.0091 0.0086
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0453 0.0449
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.2351 1
Brugia malayi follicle stimulating hormone receptor 0.0268 0.2082 0.2079
Echinococcus granulosus tachykinin peptides receptor 99D 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0037 0.0201 0.0196
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.124 1 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0079 0.0542 0.0533
Schistosoma mansoni hypothetical protein 0.0494 0.3923 0.3917
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0043 0.025 0.0245
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.0082 0.046
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0209 0.0531
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.124 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0143 0.0138
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0009 0.0009
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0058 0.0371 0.0361
Echinococcus granulosus survival motor neuron protein 1 0.0243 0.1882 0.1878
Echinococcus multilocularis Ankyrin 0.003 0.0145 0.014
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0152 0.0148
Echinococcus granulosus TRP transient receptor potential channel 0.0058 0.0371 0.0366
Brugia malayi olfactory channel protein osm-9 0.0058 0.0373 0.0369
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0103 0.0766
Echinococcus multilocularis G-protein coupled receptor, putative 0.0031 0.0152 0.0148
Toxoplasma gondii ABC1 family protein 0.0037 0.0201 0.0588
Echinococcus granulosus transient receptor potential cation channel 0.0058 0.0373 0.0368
Echinococcus granulosus voltage gated hydrogen channel 1 0.0058 0.0371 0.0366
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Treponema pallidum fructose-bisphosphate aldolase 0.0301 0.2351 1
Onchocerca volvulus 0.0044 0.0254 0.0635
Echinococcus granulosus FTZ F1 alpha 0.0079 0.0542 0.0538
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0693 0.1764
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0027 0.0122 0.0112
Brugia malayi Carboxylesterase family protein 0.0024 0.0091 0.0087
Brugia malayi phosphofructokinase 0.0112 0.0811 0.0807
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0145 0.037
Onchocerca volvulus 0.0035 0.0181 0.045
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0209 0.0531
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0152 0.0148
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0145 0.037
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0199 0.0405
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0064 0.0059
Schistosoma mansoni chromobox protein 0.0072 0.0483 0.0474
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0811 0.3287
Loa Loa (eye worm) hypothetical protein 0.0079 0.0542 0.0538
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0076 0.0517 0.0507
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.006 0.0055
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0811 0.2064
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0095 0.0537
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.003 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0412 0.0402
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0145 0.0409
Brugia malayi hypothetical protein 0.0041 0.023 0.0226
Brugia malayi Carboxylesterase family protein 0.014 0.1036 0.1033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Brugia malayi Cytochrome P450 family protein 0.0038 0.0211 0.0207
Loa Loa (eye worm) voltage-dependent calcium channel 0.0395 0.312 0.3117
Loa Loa (eye worm) hypothetical protein 0.0168 0.1268 0.1264
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0098
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0062 0.0402 0.0399
Echinococcus granulosus transient receptor potential cation channel 0.0058 0.0371 0.0366
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Loa Loa (eye worm) nuclear hormone receptor 0.0037 0.0202 0.0198
Brugia malayi Guanylate kinase family protein 0.004 0.0228 0.0224
Echinococcus granulosus sex peptide receptor 0.0031 0.0152 0.0148
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0029 0.0137 0.0234
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0811 0.2064
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0015 0.002 0.0139
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0086
Echinococcus multilocularis voltage gated potassium channel 0.0058 0.0371 0.0366
Echinococcus multilocularis transient receptor potential cation channel 0.0058 0.0371 0.0366
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0103 0.0895
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0031 0.0042
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0596 0.0587
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0055
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0179 0.0518
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus multilocularis axis inhibition protein axin 0.002 0.006 0.0055
Schistosoma mansoni MAGUK homolog 0.0043 0.025 0.024
Toxoplasma gondii exonuclease III APE 0.0019 0.0057 0.0123
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0201 0.1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0179 0.0456
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0058 0.0371 0.0366
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0079 0.0542 0.0538
Echinococcus granulosus short transient receptor potential channel 6 0.0058 0.0371 0.0366
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0811 0.0806
Echinococcus granulosus transient receptor potential cation channel 0.0222 0.1704 0.17
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0051 0.052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0079 0.0542 0.0538
Echinococcus multilocularis thyroid hormone receptor alpha 0.0079 0.0542 0.0538
Schistosoma mansoni thyroid hormone receptor 0.0079 0.0542 0.0533
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0412 0.0407
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0211 0.0206
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0153 0.1149 0.1145
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0089 0.0621 0.0616
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0201 0.0511
Echinococcus multilocularis transfer RNA-Gly 0.0062 0.0402 0.0398
Echinococcus granulosus hypothetical protein 0.0031 0.0152 0.0148
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0029 0.0137 0.1087
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0596 0.0592
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0143 0.1064 0.1061
Echinococcus multilocularis hyperpolarization activated cyclic 0.0058 0.0371 0.0366
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0079 0.0542 0.0539
Echinococcus granulosus transient receptor potential cation channel 0.0058 0.0371 0.0366
Echinococcus multilocularis musashi 0.0056 0.0357 0.0352
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0201 0.0191
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.0046
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.001 0.0005
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0104 0.01
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.001 0.0005
Schistosoma mansoni neuropeptide receptor 0.0031 0.0152 0.0142
Brugia malayi cation channel family protein 0.0058 0.0371 0.0367
Loa Loa (eye worm) RecQ helicase 0.0022 0.0078 0.0073
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0131 0.0333
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0022 0.0082 0.0576
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0152 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0144 0.0366
Echinococcus granulosus para nitrobenzyl esterase 0.0024 0.0091 0.0086
Brugia malayi abnormal cell lineage protein 2 0.004 0.0228 0.0224
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0408 0.0404
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0058 0.0371 0.0366
Loa Loa (eye worm) beta-lactamase 0.0037 0.0201 0.0196
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.003 0.0026
Echinococcus multilocularis transient receptor potential cation channel 0.0058 0.0373 0.0368
Leishmania major hypothetical protein, conserved 0.0058 0.0371 0.2181
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0025 0.0042
Echinococcus multilocularis myosin light chain kinase, smooth muscle 0.0201 0.1535 0.1531
Loa Loa (eye worm) hypothetical protein 0.003 0.0145 0.014
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0152 0.0142
Brugia malayi beta-lactamase 0.0037 0.0201 0.0197
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0005 0.0012
Echinococcus multilocularis somatostatin receptor 0.0031 0.0152 0.0148
Brugia malayi 6-phosphofructokinase 0.0112 0.0811 0.0807
Trichomonas vaginalis set domain proteins, putative 0.0494 0.3928 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0031 0.0152 0.0148
Schistosoma mansoni cpg binding protein 0.0037 0.0198 0.0188
Echinococcus granulosus potassium voltage gated channel protein 0.0143 0.1064 0.106
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0276 0.0565
Onchocerca volvulus 0.0024 0.0091 0.0219
Echinococcus multilocularis acetylcholinesterase 0.014 0.1036 0.1032
Echinococcus granulosus g-protein coupled receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0079 0.0542 0.0538
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0058 0.0371 0.0367
Schistosoma mansoni neuropeptide receptor 0.0031 0.0152 0.0142
Echinococcus granulosus geminin 0.0174 0.132 0.1316
Brugia malayi glutathione reductase 0.0065 0.0428 0.0424
Schistosoma mansoni protein phosphatase 2C 0.0016 0.003 0.002
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0079 0.0542 0.0538
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0145 0.037
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0412 0.0402
Echinococcus granulosus transient receptor potential cation channel 0.0058 0.0371 0.0366
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0022 0.0082 0.1301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0102 0.026
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0029 0.0137 0.0647
Loa Loa (eye worm) nuclear receptor NHR-67 0.0037 0.0202 0.0198
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0201 0.1679
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0015 0.0019 0.0016
Schistosoma mansoni amine GPCR 0.0031 0.0152 0.0142
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0152 0.0142
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0392 0.0387
Loa Loa (eye worm) hypothetical protein 0.0037 0.0201 0.0196
Schistosoma mansoni neuropeptide f receptor 76f 0.0031 0.0152 0.0142
Echinococcus granulosus high voltage activated calcium channel beta 0.004 0.0228 0.0223
Schistosoma mansoni jun-related protein 0.0072 0.0485 0.0476
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0029 0.0137 0.0647
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0029 0.0137 0.0647
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0408 0.0403
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0079 0.0542 0.0539
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0201 0.0409
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0079 0.0542 0.0538
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0058 0.0371 0.0361
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0104 0.0783
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Brugia malayi Guanylate kinase family protein 0.0043 0.025 0.0246
Loa Loa (eye worm) RGS-3 protein 0.002 0.006 0.0055
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Schistosoma mansoni ryanodine receptor related 0.0058 0.0371 0.0361
Mycobacterium ulcerans guanylate kinase 0.004 0.0228 0.1928
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0102 0.0261
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0022 0.0082 0.0077
Echinococcus granulosus somatostatin receptor 0.0031 0.0152 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0064
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0062 0.0402 0.0399
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0307 0.0297
Loa Loa (eye worm) hypothetical protein 0.0086 0.0601 0.0596
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0483 0.123
Loa Loa (eye worm) hypothetical protein 0.0063 0.0412 0.0407
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0058 0.0371 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0064
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0276 0.0271
Loa Loa (eye worm) hypothetical protein 0.0026 0.0111 0.0107
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.0412 0.2428
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0022 0.0082 0.1492
Echinococcus granulosus RUN 0.0041 0.023 0.0225
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0031 0.0152 0.0148
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0022 0.0082 0.0707
Leishmania major protein kinase, putative 0.0014 0.0009 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0201 0.0511
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0201 0.4438
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.0412 0.0403
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0209 0.0204
Brugia malayi hypothetical protein 0.004 0.0228 0.0224
Schistosoma mansoni rab6-interacting 0.0041 0.023 0.022
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0022 0.0082 0.0072
Onchocerca volvulus 0.0037 0.0201 0.0499
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0145 0.3072
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0042 0.0239 0.0234
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0031 0.0152 0.0148
Brugia malayi jmjC domain containing protein 0.0016 0.003 0.0027
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0025 0.0121
Brugia malayi Nuclear hormone receptor-like 1 0.0079 0.0542 0.0539
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.1096 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0022 0.0082 0.0119
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0152 0.0148
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0103 0.02
Schistosoma mansoni transient receptor potential channel 0.0058 0.0371 0.0361
Entamoeba histolytica hypothetical protein 0.0037 0.0201 0.0628
Leishmania major guanylate kinase-like protein 0.004 0.0228 0.1327
Trichomonas vaginalis discs large, putative 0.004 0.0228 0.0579
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0029 0.0137 0.0276
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0152 0.0148
Brugia malayi bZIP transcription factor family protein 0.0089 0.0621 0.0617
Schistosoma mansoni maguk P55 subfamily member 26 0.0043 0.025 0.024
Plasmodium falciparum thioredoxin reductase 0.0065 0.0428 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0349 0.0344
Entamoeba histolytica hypothetical protein 0.0037 0.0201 0.0628
Onchocerca volvulus 0.0031 0.0152 0.0376
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0147 0.2931
Echinococcus granulosus high voltage activated calcium channel beta 0.0551 0.4387 0.4384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0124 0.0316
Loa Loa (eye worm) hypothetical protein 0.0056 0.0357 0.0352
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0201 0.0196
Onchocerca volvulus 0.0024 0.0091 0.0219
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0104 0.0783
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0022 0.0082 0.0205
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0201 0.0511
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0062 0.0402 0.0398
Echinococcus multilocularis voltage dependent calcium channel 0.124 1 1
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0043 0.025 0.0245
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0276 0.0271
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0031 0.0152 0.0142
Mycobacterium leprae putative cytochrome p450 0.0029 0.0137 0.1211
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0079 0.0542 0.0538
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0011 0.0001
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0058 0.0371 0.0764
Echinococcus granulosus potassium voltage gated channel protein 0.0062 0.0402 0.0398
Entamoeba histolytica hypothetical protein 0.0024 0.0095 0.0167
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.006 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0029 0.0137 0.0647
Echinococcus multilocularis orexin receptor type 2 0.0031 0.0152 0.0148
Schistosoma mansoni hypothetical protein 0.005 0.0303 0.0294
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0152 0.0142
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0152 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0149
Onchocerca volvulus 0.0031 0.0152 0.0376
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0022 0.0082 0.046
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.006 0.0055
Schistosoma mansoni polycystin 1-related 0.0041 0.023 0.022
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0693 0.1764
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0145 0.3072
Brugia malayi chromobox protein homolog 3 0.004 0.0226 0.0223
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0104 0.0266
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0145 0.6299
Schistosoma mansoni opsin-like receptor 0.0031 0.0152 0.0142
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0276 0.1614
Echinococcus multilocularis two pore calcium channel protein 1 0.0058 0.0371 0.0366
Echinococcus granulosus sodium channel protein 0.0058 0.0371 0.0366
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0811 0.0806
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Onchocerca volvulus 0.0086 0.0596 0.1507
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0211 0.1769
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0693 0.1764
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0059 0.0149
Brugia malayi PXA domain containing protein 0.002 0.006 0.0056
Schistosoma mansoni hypothetical protein 0.0041 0.023 0.022
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0058 0.0371 0.0367
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0029 0.0137 0.0647
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0149
Brugia malayi jmjC domain containing protein 0.0016 0.003 0.0027
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0402 0.0393
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0103 0.0766
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0009 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0145 0.037
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0055
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0031 0.0152 0.0142
Echinococcus multilocularis guanylate kinase 0.004 0.0228 0.0223
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.003 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0079 0.0542 0.137
Loa Loa (eye worm) ion channel NompC 0.0058 0.0371 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0693 0.1764
Brugia malayi nuclear receptor RXR 0.0037 0.0202 0.0199
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.003 0.0026
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0031 0.0152 0.0148
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0226 0.0564
Leishmania major cytochrome p450-like protein 0.0029 0.0137 0.0787
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0079 0.0542 0.0538
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0568 0.453 0.4527
Brugia malayi beta-lactamase family protein 0.0037 0.0201 0.0197
Loa Loa (eye worm) hypothetical protein 0.0243 0.1882 0.1878
Echinococcus granulosus calcium activated potassium channel 0.0058 0.0375 0.037
Mycobacterium tuberculosis Probable oxidoreductase 0.0022 0.0082 0.0343
Onchocerca volvulus Netrin receptor homolog 0.0032 0.0163 0.0403
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0811 0.0806
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0056 0.0647
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0293 0.0745
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0078 0.0074
Echinococcus granulosus hyperpolarization activated cyclic 0.0058 0.0371 0.0366
Plasmodium vivax SET domain protein, putative 0.0063 0.0412 0.9614
Brugia malayi Tachykinin-like peptides receptor 99D 0.0031 0.0152 0.0149
Schistosoma mansoni lamin 0.0056 0.0357 0.0347
Schistosoma mansoni lipoxygenase 0.0105 0.0756 0.0747
Echinococcus granulosus phd:f box containing protein 0.0016 0.003 0.0026
Echinococcus multilocularis chromobox protein 1 0.0072 0.0483 0.0479
Mycobacterium leprae Probable lipase LipE 0.0037 0.0201 0.1795
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2351 0.5985
Plasmodium falciparum guanylate kinase 0.004 0.0228 0.4963
Echinococcus granulosus two pore calcium channel protein 2 0.0058 0.0371 0.0366
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.006 0.005
Schistosoma mansoni hypothetical protein 0.0031 0.0152 0.0142
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0029 0.0137 0.1087
Toxoplasma gondii transporter, cation channel family protein 0.0058 0.0371 0.1136
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0095 0.0414
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.1828 1
Echinococcus multilocularis shaker cognate 0.0062 0.0402 0.0398
Onchocerca volvulus 0.0024 0.0091 0.0219
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Brugia malayi Doublecortin family protein 0.0041 0.023 0.0226
Brugia malayi G protein-coupled receptor F59B2.13 0.0031 0.0152 0.0149
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.012 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0102 0.026
Schistosoma mansoni amine GPCR 0.0031 0.0152 0.0142
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0693 0.1435
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0145 0.037
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0031 0.0026
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0031 0.0158
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Echinococcus granulosus hyperpolarization activated cyclic 0.0058 0.0371 0.0366
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0031 0.0152 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0064
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Brugia malayi CHD4 protein 0.0014 0.0011 0.0007
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0031 0.0013
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0057 0.0901
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0005 0.0000019692
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0075 0.0508 0.0498
Brugia malayi Cytochrome P450 family protein 0.0029 0.0137 0.0133
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.023 0.0225
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0064 0.0059
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.124 1 1
Brugia malayi nuclear receptor RXR 0.0042 0.0239 0.0235
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0102 0.026
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0152 0.0142
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0024 0.0091 0.0086
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0058 0.0371 0.0361
Schistosoma mansoni adenoreceptor 0.0031 0.0152 0.0142
Mycobacterium tuberculosis Conserved protein 0.0025 0.0104 0.0466
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Brugia malayi orphan nuclear receptor NR2E1 0.0037 0.0202 0.0199
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0078 0.0198
Echinococcus granulosus dro:myosuppressin receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) steroid hormone receptor 0.0079 0.0542 0.0538
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.124 1 1
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0058 0.0371 0.0933
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0037 0.0202 0.0198
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0031 0.0026
Brugia malayi Melatonin receptor type 1A 0.0031 0.0152 0.0149
Onchocerca volvulus 0.0075 0.0508 0.1281
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0103 0.0766
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0095 0.0146
Mycobacterium tuberculosis Conserved protein 0.0037 0.0201 0.1
Echinococcus multilocularis potassium voltage gated channel protein 0.0058 0.0371 0.0366
Echinococcus granulosus potassium large conductance calcium activated 0.0058 0.0371 0.0366
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0152 0.0148
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0031 0.0062
Schistosoma mansoni biogenic amine receptor 0.0031 0.0152 0.0142
Loa Loa (eye worm) hypothetical protein 0.0037 0.0201 0.0196
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0152 0.0148
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0104 0.0207
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0057 0.0202
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0152 0.0142
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0031 0.0152 0.0142
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0811 0.48
Onchocerca volvulus 0.0032 0.016 0.0395
Echinococcus multilocularis MAGUK p55 subfamily 0.0043 0.025 0.0245
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0412 0.0407
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0425
Brugia malayi larval opioid receptor 0.0031 0.0152 0.0149
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0357 0.0353
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0029 0.0137 0.1087
Onchocerca volvulus 0.0025 0.0103 0.0249
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0349 0.0339
Schistosoma mansoni inositol monophosphatase 0.0038 0.0209 0.0199
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0209 0.0613
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0057 0.0108
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0349 0.0344
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0058 0.0371 0.0366
Schistosoma mansoni intermediate filament proteins 0.0056 0.0357 0.0347
Mycobacterium ulcerans beta-lactamase 0.0037 0.0201 0.1679
Echinococcus granulosus g protein coupled receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0068 0.0452 0.0448
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0029 0.0137 0.1087
Treponema pallidum NADH oxidase 0.0022 0.0082 0.0111
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0147 0.2931
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.006 0.005
Echinococcus multilocularis cpg binding protein 0.0037 0.0198 0.0193
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0025 0.002
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0058 0.0371 0.0367
Schistosoma mansoni regulator of G protein signaling 0.002 0.006 0.005
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0453 0.2667
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0058 0.0371 0.0367
Trypanosoma cruzi guanylate kinase, putative 0.004 0.0228 0.0465
Brugia malayi hypothetical protein 0.0037 0.0201 0.0197
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0022 0.0082 0.1526
Schistosoma mansoni BC026374 protein (S09 family) 0.0024 0.0091 0.0081
Onchocerca volvulus 0.0031 0.0152 0.0376
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0025 0.0042
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0176 0.1569
Echinococcus granulosus ankyrin repeat protein 0.0164 0.1232 0.1228
Brugia malayi hypoxia-induced factor 1 0.0155 0.1162 0.1158
Schistosoma mansoni voltage-dependent calcium channel 0.0058 0.0371 0.0361
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0005 0.0012
Brugia malayi G-protein coupled receptor 0.0031 0.0152 0.0149
Schistosoma mansoni kinase 0.005 0.0303 0.0293
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0239 0.0229
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0152 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0179 0.0456
Loa Loa (eye worm) hypothetical protein 0.0042 0.0239 0.0234
Schistosoma mansoni netrin receptor unc5 0.003 0.0143 0.0133
Brugia malayi hypothetical protein 0.0243 0.1882 0.1879
Onchocerca volvulus 0.0031 0.0152 0.0376
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0058 0.0371 0.0367
Schistosoma mansoni cell polarity protein 0.0043 0.025 0.024
Brugia malayi neuropeptide F receptor 0.0031 0.0152 0.0149
Schistosoma mansoni ATP-dependent RNA Helicase 0.0043 0.025 0.024
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0058 0.0371 0.0367
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0201 0.1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0029 0.0137 0.1087
Schistosoma mansoni voltage-gated cation channel 0.124 1 1
Echinococcus granulosus G protein coupled receptor 139 0.0031 0.0152 0.0148
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0104 0.0783
Onchocerca volvulus 0.0031 0.0152 0.0376
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0058 0.0371 0.0366
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0201 0.0197
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0058 0.0371 0.0361
Leishmania major guanylate kinase, putative 0.004 0.0228 0.1327
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.003 0.0026
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0062 0.0402 0.0398
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0057 0.0066
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0239 0.0235
Loa Loa (eye worm) carboxylesterase 0.014 0.1036 0.1032
Schistosoma mansoni MAGUK homolog 0.0044 0.0254 0.0244
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Giardia lamblia NADH oxidase lateral transfer candidate 0.0022 0.0082 0.0111
Loa Loa (eye worm) hypothetical protein 0.0079 0.0542 0.0538
Schistosoma mansoni axis inhibition protein axin 0.002 0.006 0.005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0145 0.2889
Echinococcus granulosus 7tm_1 domain containing protein 0.0031 0.0152 0.0148
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0412 0.1269
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0152 0.0148
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0058 0.0371 0.0366
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0811 0.3287
Schistosoma mansoni maguk P55 subfamily member 26 0.004 0.0228 0.0218
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0025 0.0121
Onchocerca volvulus 0.005 0.0303 0.0761
Echinococcus multilocularis serotonin receptor 0.0031 0.0152 0.0148
Plasmodium falciparum glutathione reductase 0.0022 0.0082 0.1301
Onchocerca volvulus 0.007 0.0466 0.1174
Loa Loa (eye worm) hypothetical protein 0.0079 0.0542 0.0538
Echinococcus multilocularis axis inhibition protein axin 0.002 0.006 0.0055
Onchocerca volvulus 0.0031 0.0152 0.0376
Loa Loa (eye worm) voltage-gated potassium channel 0.0058 0.0371 0.0366
Echinococcus multilocularis g-protein coupled receptor 0.0031 0.0152 0.0148
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0079 0.0542 0.0539
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0145 0.6299
Schistosoma mansoni amine GPCR 0.0031 0.0152 0.0142
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0201 0.0197
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0483 0.0479
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0011 0.0006
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.006 0.0152
Onchocerca volvulus 0.0056 0.0357 0.0897
Schistosoma mansoni z-protein (S1r protein) 0.002 0.006 0.005
Brugia malayi hypothetical protein 0.0041 0.023 0.0226
Schistosoma mansoni high voltage-activated calcium channel beta subunit 1 0.0551 0.4387 0.4382
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0037 0.0202 0.0193
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0029 0.0137 0.0647
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0057 0.0659
Echinococcus multilocularis neuropeptide FF receptor 2 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0058 0.0371 0.0366
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0079 0.0542 0.0538
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0201 0.1
Echinococcus multilocularis voltage gated potassium channel 0.0062 0.0402 0.0398
Brugia malayi ORL1-like opioid receptor 0.0031 0.0152 0.0149
Loa Loa (eye worm) acetylcholinesterase 1 0.014 0.1036 0.1032
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Brugia malayi hypothetical protein 0.002 0.006 0.0056
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0057 0.0339
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0103 0.0895
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0022 0.0082 0.0119
Loa Loa (eye worm) hypothetical protein 0.0395 0.312 0.3117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0149
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0152 0.0148
Leishmania major hypothetical protein, conserved 0.0219 0.1683 1
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0064 0.0059
Brugia malayi Nuclear hormone receptor E75 0.0037 0.0202 0.0199
Echinococcus multilocularis sodium channel protein 0.0264 0.205 0.2046
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0079 0.0542 0.0533
Brugia malayi beta-lactamase family protein 0.0037 0.0201 0.0197
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0079 0.0542 0.0538
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0005 0.0012
Onchocerca volvulus 0.0037 0.0201 0.0499
Loa Loa (eye worm) hypothetical protein 0.0041 0.023 0.0225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0152 0.0142
Schistosoma mansoni microtubule-associated protein tau 0.071 0.5687 0.5683
Echinococcus multilocularis serine:threonine protein kinase 0.0201 0.1535 0.1531
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0015 0.0019 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0012
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0089 0.0621 0.0616
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0102 0.0261
Echinococcus granulosus peptide allatostatin:somatostatin 0.0031 0.0152 0.0148
Echinococcus granulosus voltage dependent calcium channel 0.0395 0.312 0.3117
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0079 0.0542 0.0533
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0058 0.0371 0.0366
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0079 0.0542 0.0539
Brugia malayi cytochrome P450 0.0029 0.0137 0.0133
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0811 0.2064
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0022 0.0082 0.3467
Echinococcus granulosus serotonin receptor 0.0031 0.0152 0.0148
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0408 0.3605
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0022 0.0082 0.0576
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.124 1 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0145 0.0386
Onchocerca volvulus 0.0031 0.0152 0.0376
Schistosoma mansoni hypothetical protein 0.0174 0.132 0.1311
Entamoeba histolytica hypothetical protein 0.002 0.006 0.0013
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0408 0.2146
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0811 0.1645
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0086
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0408 0.0399
Brugia malayi jmjC domain containing protein 0.0016 0.003 0.0027
Schistosoma mansoni hypothetical protein 0.0174 0.132 0.1311
Echinococcus granulosus expressed protein 0.0384 0.303 0.3027
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0211 0.0206
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0152 0.0148
Echinococcus multilocularis geminin 0.0174 0.132 0.1316
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0693 0.0689
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0029 0.0137 0.1087
Echinococcus granulosus netrin receptor unc 5 0.003 0.0143 0.0138
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0596 0.0593
Brugia malayi hypothetical protein 0.0037 0.0202 0.0199
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0147 0.0414
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0131 0.0333
Brugia malayi Dopamine receptor protein 2 0.0031 0.0152 0.0149
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0693 0.1764
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0349 0.0344
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0079 0.0542 0.0539
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0095 0.0247
Echinococcus granulosus thioredoxin glutathione reductase 0.0065 0.0428 0.0423
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.023 0.0225
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0079 0.0542 0.0538
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0005 0.0012
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.003 0.0143 0.0138
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0408 0.0399
Loa Loa (eye worm) hypothetical protein 0.014 0.1036 0.1032
Leishmania major hypothetical protein, conserved 0.0037 0.0201 0.1168
Echinococcus multilocularis high voltage activated calcium channel beta 0.004 0.0228 0.0223
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0201 0.0191
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0103 0.0582
Schistosoma mansoni gliotactin 0.0024 0.0091 0.0081
Onchocerca volvulus 0.0031 0.0152 0.0376
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0103 0.02
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0044 0.0254 0.0249
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0201 0.1
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0044 0.0254 0.0249
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0147 0.0296
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0103 0.0099
Loa Loa (eye worm) inositol-1 0.0038 0.0209 0.0204
Echinococcus multilocularis RUN 0.0041 0.023 0.0225
Toxoplasma gondii transporter, cation channel family protein 0.0058 0.0371 0.1136
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0079 0.0542 0.0538
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0031 0.0028
Loa Loa (eye worm) lethal(1)discs large-1 tumor suppressor 0.004 0.0228 0.0223
Schistosoma mansoni amine GPCR 0.0031 0.0152 0.0142
Loa Loa (eye worm) hypothetical protein 0.0016 0.003 0.0026
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0058 0.0371 0.0361
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0178 0.1351 0.1347
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.006 0.0055
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0349 0.0345
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Onchocerca volvulus 0.0031 0.0152 0.0376
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0078 0.0073
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0137 0.0276
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0012
Loa Loa (eye worm) doublecortin family protein 0.0041 0.023 0.0225
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0032 0.016 0.0282
Echinococcus multilocularis allatostatin A receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.124 1 1
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0104 0.0593
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0124 0.0316
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0201 0.0196
Echinococcus granulosus orexin receptor type 2 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0091 0.0638 0.0633
Schistosoma mansoni lamin 0.0056 0.0357 0.0347
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0032 0.0156 0.0151
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0029 0.0137 0.0647
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0031 0.0042
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0017 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0016 0.003 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2351 0.5985
Trypanosoma brucei polo-like protein kinase 0.0097 0.0693 0.1398
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0264 0.205 0.2046
Schistosoma mansoni ap endonuclease 0.0019 0.0057 0.0047
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0408 0.0399
Trypanosoma cruzi trypanothione reductase, putative 0.0022 0.0082 0.0161
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0098
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Brugia malayi voltage-dependent calcium channel 0.0058 0.0371 0.0367
Trichomonas vaginalis esterase, putative 0.0037 0.0201 0.0511
Schistosoma mansoni calcium-activated potassium channel 0.0058 0.0371 0.0361
Leishmania major hypothetical protein, conserved 0.0039 0.0216 0.126
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0077 0.0109
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.003 0.0026
Echinococcus multilocularis sex peptide receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.124 1 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0276 0.1614
Schistosoma mansoni regulator of G protein signaling 0.002 0.006 0.005
Echinococcus granulosus two pore calcium channel protein 1 0.0058 0.0371 0.0366
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.124 1 1
Echinococcus granulosus dnaJ subfamily B 0.0494 0.3923 0.392
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.003 0.0026
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0425
Mycobacterium ulcerans lipase LipD 0.0037 0.0201 0.1679
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0058 0.0371 0.0361
Brugia malayi ZU5 domain containing protein 0.004 0.0228 0.0224
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0022 0.0082 0.0343
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.003 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2351 0.5985
Echinococcus multilocularis potassium voltage gated channel protein 0.0062 0.0402 0.0398
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0047 0.0042
Echinococcus multilocularis carboxylesterase 5A 0.014 0.1036 0.1032
Onchocerca volvulus 0.0031 0.0152 0.0376
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0042 0.0239 0.0234
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2351 0.5985
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0064
Schistosoma mansoni voltage-gated potassium channel 0.0143 0.1064 0.1055
Echinococcus multilocularis survival motor neuron protein 1 0.0243 0.1882 0.1878
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0453 0.0448
Schistosoma mansoni amine GPCR 0.0031 0.0152 0.0142
Brugia malayi indoleamine 2,3-dioxygenase 0.0568 0.453 0.4528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0276 0.0702
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0103 0.0456
Plasmodium vivax guanylate kinase, putative 0.004 0.0228 0.5093
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0011 0.0006
Loa Loa (eye worm) voltage-gated potassium channel 0.0062 0.0402 0.0398
Brugia malayi Carboxylesterase family protein 0.0024 0.0091 0.0087
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0104 0.0207
Echinococcus multilocularis 0.0029 0.0137 0.0132
Brugia malayi hypothetical protein 0.002 0.0059 0.0055
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0402 0.0393
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0102 0.0261
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Echinococcus multilocularis ryanodine receptor 44f 0.0058 0.0371 0.0366
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0091 0.0392
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0005 0.0000019692
Brugia malayi putative neuropeptide receptor NPR1 0.0031 0.0152 0.0149
Onchocerca volvulus 0.0041 0.023 0.0573
Mycobacterium tuberculosis Carboxylesterase LipT 0.0024 0.0091 0.0392
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0011 0.0006
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0079 0.0542 0.0533
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0022 0.0082 0.046
Brugia malayi nuclear receptor NHR-88 0.0037 0.0202 0.0199
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0025 0.0021
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0082 0.0072
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0835 0.6701 0.6699
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Schistosoma mansoni hydrolase 0.0039 0.0216 0.0207
Loa Loa (eye worm) hypothetical protein 0.0037 0.0201 0.0196
Trypanosoma brucei hypothetical protein, conserved 0.0219 0.1683 0.3474
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0029 0.0137 0.1087
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0568 0.453 0.4527
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0103 0.0766
Echinococcus multilocularis neuropeptide s receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0037 0.0202 0.0198
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0029 0.0137 0.1087
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0058 0.0371 0.0361
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0201 0.0196
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0276 0.0565
Schistosoma mansoni opsin-like receptor 0.0031 0.0152 0.0142
Giardia lamblia Fructose-bisphosphate aldolase 0.0301 0.2351 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0102 0.0261
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0082 0.0161
Brugia malayi conserved hypotetical protein 0.0037 0.0202 0.0199
Echinococcus granulosus axis inhibition protein axin 0.002 0.006 0.0055
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0095 0.1842
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0042 0.0239 0.0234
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0058 0.0371 0.0944
Leishmania major hypothetical protein, conserved 0.003 0.0147 0.0846
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0029 0.0137 0.1087
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0276 0.0525
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.003 0.002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0079 0.0542 0.0539
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0031 0.0152 0.0148
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0029 0.0137 0.0647
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0693 0.4098
Echinococcus granulosus abhydrolase domain containing protein 0.0039 0.0216 0.0212
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0027 0.012 0.0115
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0031 0.0026
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0152 0.0148
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0164 0.1232 0.1223
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0103 0.0766
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0103 0.0099
Echinococcus granulosus g protein coupled receptor 0.0031 0.0152 0.0148
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0057 0.0308
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0031 0.0152 0.0142
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0082 0.0161
Echinococcus multilocularis transient receptor potential cation channel 0.0222 0.1707 0.1702
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0031 0.0152 0.0148
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0029 0.0137 0.0647
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0251 0.0628
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0152 0.0148
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.004 0.0228 0.0218
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0201 0.0196
Giardia lamblia Guanylate kinase 0.004 0.0228 0.0745
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0057 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0079 0.0542 0.0539
Brugia malayi Steroid receptor seven-up type 2 0.0079 0.0542 0.0539
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0029 0.0137 0.0647
Loa Loa (eye worm) hypoxia-induced factor 1 0.0155 0.1162 0.1157
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0058 0.0371 0.0361
Echinococcus granulosus shaker cognate 0.0062 0.0402 0.0398
Toxoplasma gondii guanylate kinase family protein 0.004 0.0228 0.0674
Plasmodium falciparum thioredoxin reductase 0.0022 0.0082 0.1301
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.006 0.0056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0152 0.0142
Brugia malayi Cytochrome P450 family protein 0.0088 0.0617 0.0614
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0453 0.0448
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0043 0.025 0.0245
Echinococcus granulosus lamin 0.0056 0.0357 0.0352
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2351 0.5985
Echinococcus granulosus guanylate kinase 0.004 0.0228 0.0223
Echinococcus multilocularis acetylcholinesterase 0.014 0.1036 0.1032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0122 0.031
Echinococcus granulosus neuropeptide receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0219 0.0215
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0051 0.0171
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0029 0.0137 0.1087
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0029 0.0137 0.0647
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0037 0.0202 0.0503
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0239 0.0235
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0811 0.0806
Schistosoma mansoni two-pore calcium channel 0.0058 0.0371 0.0361
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0029 0.0137 0.1087
Onchocerca volvulus 0.0058 0.0371 0.0933
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0152 0.0148
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0811 0.3287
Loa Loa (eye worm) guanylate kinase 0.004 0.0228 0.0223
Echinococcus granulosus disks large 1 0.004 0.0228 0.0223
Echinococcus granulosus guanylate kinase 0.004 0.0228 0.0223
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0055 0.0348 0.0344
Echinococcus multilocularis short transient receptor potential channel 6 0.0058 0.0373 0.0368
Echinococcus granulosus neuropeptide receptor 0.0031 0.0152 0.0148
Brugia malayi PAS domain containing protein 0.005 0.0307 0.0303
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.1096 0.5953
Mycobacterium tuberculosis Conserved protein 0.0037 0.0201 0.1
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0055
Echinococcus multilocularis ankyrin repeat protein 0.0164 0.1232 0.1228
Echinococcus granulosus bloom syndrome protein 0.0022 0.0078 0.0073
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0022 0.0082 0.0343
Schistosoma mansoni hypothetical protein 0.0029 0.0137 0.0127
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus granulosus amyloid beta A4 protein 0.0071 0.0475 0.047
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.3923 0.392
Schistosoma mansoni biogenic amine receptor 0.0031 0.0152 0.0142
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0055
Brugia malayi hypothetical protein 0.0042 0.0239 0.0235
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0209 0.0204
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0453 0.0934
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0078 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0029 0.0137 0.0647
Echinococcus multilocularis hyperpolarization activated cyclic 0.0058 0.0371 0.0366
Mycobacterium tuberculosis Conserved protein 0.0037 0.0201 0.1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0693 0.0683
Echinococcus granulosus cpg binding protein 0.0037 0.0198 0.0193
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0412 0.3645
Onchocerca volvulus 0.0031 0.0152 0.0376
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.1096 1
Onchocerca volvulus 0.0031 0.0152 0.0376
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0079 0.0542 0.0533
Loa Loa (eye worm) hypothetical protein 0.004 0.0228 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0179 0.0456
Echinococcus granulosus potassium voltage gated channel protein 0.0058 0.0371 0.0366
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0408 0.3605
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0029 0.0137 0.0647
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0082 0.0161
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0147 0.0255
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0029 0.0137 0.1087
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0031 0.0152 0.0148
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Loa Loa (eye worm) cytochrome P450 0.0029 0.0137 0.0132
Brugia malayi G protein-coupled receptor 0.0031 0.0152 0.0149
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0811 0.3287
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0357 0.0352
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0079 0.0542 0.0539
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0371 0.1136
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0042 0.0239 0.0234
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0082 0.0161
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0181 0.0177
Schistosoma mansoni coup transcription factor 0.0079 0.0542 0.0533
Schistosoma mansoni maguk P55 subfamily member 35 0.0043 0.025 0.024
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0303 0.03
Echinococcus granulosus alpha 1A adrenergic receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis potassium voltage gated channel protein 0.0143 0.1064 0.106
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0058 0.0371 0.0366
Schistosoma mansoni phd/f-box containing protein 0.0016 0.003 0.002
Echinococcus multilocularis abhydrolase domain containing protein 0.0039 0.0216 0.0212
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.023 0.0225
Echinococcus granulosus MAGUK p55 subfamily 0.0043 0.025 0.0245
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.004 0.003
Schistosoma mansoni nuclear hormone receptor 0.0079 0.0542 0.0533
Echinococcus granulosus MAGUK p55 subfamily 0.0043 0.025 0.0245
Onchocerca volvulus 0.0031 0.0152 0.0376
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.006 0.0055
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0058 0.0371 0.0366
Echinococcus granulosus potassium voltage gated channel protein 0.0062 0.0402 0.0398
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0152 0.0386
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0145 0.0409
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.023 0.5143
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0079 0.0542 0.0539
Loa Loa (eye worm) hypothetical protein 0.0037 0.0201 0.0196
Schistosoma mansoni nuclear receptor 0.0037 0.0202 0.0193
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0031 0.0152 0.0148
Onchocerca volvulus 0.0037 0.0201 0.0499
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0453 0.1726
Brugia malayi CXXC zinc finger family protein 0.0035 0.0181 0.0178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0199 0.0506
Loa Loa (eye worm) hypothetical protein 0.0041 0.023 0.0225
Echinococcus multilocularis lamin 0.0056 0.0357 0.0352
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.006 0.0056
Echinococcus multilocularis chromobox protein 1 0.0072 0.0483 0.0479
Plasmodium vivax thioredoxin reductase, putative 0.0065 0.0428 1
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0152 0.0148
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0031 0.0152 0.0142
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0031 0.0152 0.0148
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0005 0.0000019692
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0091 0.0081
Entamoeba histolytica hypothetical protein 0.0037 0.0201 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.002 0.006 0.0152
Onchocerca volvulus 0.0056 0.0357 0.0897
Schistosoma mansoni jumonji domain containing protein 0.0016 0.003 0.002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0005 0.0012
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.006 0.0056
Brugia malayi Serotonin receptor 0.0031 0.0152 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.002 0.006 0.0152
Brugia malayi Cytochrome P450 family protein 0.0038 0.0211 0.0207
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0058 0.0371 0.0361
Brugia malayi nuclear hormone receptor family member odr-7 0.0037 0.0202 0.0199
Brugia malayi hypothetical protein 0.0031 0.0152 0.0149
Onchocerca volvulus 0.0037 0.0201 0.0499
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Loa Loa (eye worm) voltage-gated calcium channel 0.0058 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0079 0.0542 0.0538
Echinococcus multilocularis BC026374 protein (S09 family) 0.0024 0.0091 0.0086
Schistosoma mansoni cell polarity protein 0.004 0.0228 0.0218
Loa Loa (eye worm) guanylate kinase 0.0043 0.025 0.0245
Echinococcus multilocularis dro:myosuppressin receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0031 0.0026
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0601 0.4799 1
Brugia malayi nuclear hormone receptor 0.0079 0.0542 0.0539
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0058 0.0371 0.0361
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0037 0.0202 0.0199
Onchocerca volvulus 0.0041 0.023 0.0573
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0058 0.0371 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0226 0.0577
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.023 0.0225
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0149
Brugia malayi ecdysteroid receptor 0.0079 0.0542 0.0539
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0104 0.01
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0029 0.0137 0.1087
Brugia malayi photoreceptor-specific nuclear receptor 0.0079 0.0542 0.0539
Echinococcus granulosus neuroligin 0.0024 0.0091 0.0086
Brugia malayi Guanylate kinase family protein 0.0043 0.025 0.0246
Schistosoma mansoni neuropeptide receptor 0.0031 0.0152 0.0142
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0037 0.0202 0.0198
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0601 0.4799 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0387 0.0382
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0058 0.0371 0.0361
Brugia malayi isocitrate dehydrogenase 0.0016 0.0031 0.0028
Brugia malayi jmjC domain containing protein 0.0016 0.003 0.0027
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0022 0.0082 0.0576
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.004 0.0228 0.0224
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.0082 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.002 0.006 0.0152
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0152 0.0148
Trichomonas vaginalis calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase, putative 0.004 0.0228 0.0579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0122 0.031
Brugia malayi hypothetical protein 0.007 0.0466 0.0462
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.023 0.0225
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0371 0.1136
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0022 0.0082 0.0078
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0057 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2351 0.5985
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0811 0.0801
Brugia malayi Pre-SET motif family protein 0.0435 0.3439 0.3437
Plasmodium falciparum epoxide hydrolase 1 0.0039 0.0216 0.4681
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.003 0.0039
Toxoplasma gondii hypothetical protein 0.0058 0.0371 0.1136
Loa Loa (eye worm) carboxylesterase 0.0024 0.0091 0.0086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0104 0.0466
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Loa Loa (eye worm) thioredoxin reductase 0.0065 0.0428 0.0423
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.006 0.0055
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Loa Loa (eye worm) hypothetical protein 0.0079 0.0542 0.0538
Leishmania major trypanothione reductase 0.0065 0.0428 0.2519
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0201 0.1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0029 0.0137 0.1087
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Schistosoma mansoni single-minded 0.005 0.0307 0.0297
Loa Loa (eye worm) TYRA-2 protein 0.0031 0.0152 0.0148
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0145 0.0409
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.2351 0.5985
Mycobacterium ulcerans hypothetical protein 0.0025 0.0104 0.0783
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0025 0.0015
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0058 0.0371 0.0366
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0201 0.0368
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0091 0.0392
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0276 0.0266
Plasmodium vivax glutathione reductase, putative 0.0065 0.0428 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0152 0.0148
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0095 0.1626
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Schistosoma mansoni transient receptor potential channel 0.0058 0.0371 0.0361
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0152 0.0142
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0031 0.0024
Entamoeba histolytica hypothetical protein 0.002 0.006 0.0013
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0693 0.0688
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0031 0.0026
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0058 0.0371 0.0366
Brugia malayi Dopamine receptor 0.0031 0.0152 0.0149
Brugia malayi nuclear receptor NHR-88 0.0079 0.0542 0.0539
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0103 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0402 0.0393
Echinococcus multilocularis FTZ F1 alpha 0.0079 0.0542 0.0538
Echinococcus granulosus ryanodine receptor 44f 0.0058 0.0371 0.0366
Toxoplasma gondii hypothetical protein 0.0058 0.0371 0.1136
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.003 0.0026
Brugia malayi Serotonin receptor 0.0505 0.4011 0.4009
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0031 0.0152 0.0149
Loa Loa (eye worm) hypothetical protein 0.0058 0.0373 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0124 0.0316
Echinococcus multilocularis regulator of G protein signaling 0.002 0.006 0.0055
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0201 0.1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0693 0.1753
Brugia malayi hypothetical protein 0.0091 0.0638 0.0634
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0211 0.0388
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0079 0.0542 0.0539
Brugia malayi Death domain containing protein 0.003 0.0143 0.0139
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0276 0.0956
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0276 0.0702
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0412 0.0408
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0139 0.1033 0.1028
Schistosoma mansoni hypothetical protein 0.0058 0.0371 0.0361
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0152 0.0142
Echinococcus multilocularis neuroligin 0.0024 0.0091 0.0086
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0152 0.0142
Schistosoma mansoni thyroid hormone receptor 0.0079 0.0542 0.0533
Echinococcus multilocularis ecdysone induced protein 78C 0.0079 0.0542 0.0538
Echinococcus multilocularis phd:f box containing protein 0.0016 0.003 0.0026
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.006 0.0056
Schistosoma mansoni growth hormone secretagogue receptor 0.0031 0.0152 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.002 0.006 0.0152
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0058 0.0371 0.0367
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0057 0.0144
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.023 0.5014
Brugia malayi Cyclic-nucleotide gated cation channel 0.0058 0.0371 0.0367
Brugia malayi Transient-receptor-potential like protein 0.0058 0.0371 0.0367
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0062 0.0402 0.0398
Schistosoma mansoni ankyrin 23/unc44 0.003 0.0143 0.0133
Brugia malayi hydrolase, alpha/beta fold family protein 0.0039 0.0216 0.0213
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0015
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0031 0.0152 0.0149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0059 0.0149
Schistosoma mansoni regulator of G protein signaling 0.002 0.006 0.005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0152 0.0148
Schistosoma mansoni voltage-gated potassium channel 0.0143 0.1064 0.1055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.0046
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0025 0.002
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0176 0.0863
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0025 0.0064
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0037 0.0202 0.0198
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0152 0.0148
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0811 0.7381
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0408 0.0403
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0209 0.0531
Echinococcus multilocularis disks large 3 0.0043 0.025 0.0245
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0147 0.3113
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0693 0.1764
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0058 0.0371 0.0366
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0037 0.0202 0.0193
Trichomonas vaginalis guanylate kinase, putative 0.004 0.0228 0.0579
Brugia malayi GnHR receptor homolog 0.0031 0.0152 0.0149
Schistosoma mansoni voltage-gated ion channel 0.0058 0.0371 0.0361
Echinococcus granulosus short transient receptor potential channel 6 0.0058 0.0373 0.0368
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0412 0.0407
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0811 0.2064
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0051 0.0288
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0031 0.0152 0.0148
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0219 0.0215
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.0082 0.0161
Schistosoma mansoni nuclear hormone receptor 0.0037 0.0202 0.0193
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.004 0.0228 0.0223
Loa Loa (eye worm) glutathione reductase 0.0065 0.0428 0.0423
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Echinococcus multilocularis transient receptor potential cation channel 0.0058 0.0371 0.0366
Echinococcus granulosus death domain containing protein 0.003 0.0143 0.0138
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0059 0.0149
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0057 0.0144
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0017 0.0033 0.003
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0145 0.0386
Echinococcus granulosus transient receptor potential cation channel 0.0058 0.0371 0.0366
Onchocerca volvulus 0.0037 0.0202 0.0503
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0143 0.0138
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0051 0.2074
Brugia malayi Dopamine receptor protein 1 0.0031 0.0152 0.0149
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0201 0.0191
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0453 0.0895
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0144 0.0139
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0209 0.8894
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0031 0.0152 0.0148
Brugia malayi G-protein coupled receptor 0.0031 0.0152 0.0149
Onchocerca volvulus 0.0079 0.0542 0.137
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis microtubule associated protein 2 0.071 0.5687 0.5685
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0152 0.0142
Brugia malayi Peripheral plasma membrane protein CASK 0.0043 0.025 0.0246
Plasmodium vivax JmjC domain containing protein 0.0016 0.003 0.0258
Onchocerca volvulus 0.0024 0.0091 0.0219
Loa Loa (eye worm) DR-78 0.0037 0.0202 0.0198
Echinococcus multilocularis MAGUK p55 subfamily 0.0043 0.025 0.0245
Schistosoma mansoni RAR-like nuclear receptor 0.0079 0.0542 0.0533
Schistosoma mansoni myosin xvIII 0.0031 0.0152 0.0142
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.006 0.0055
Echinococcus granulosus acetylcholinesterase 0.014 0.1036 0.1032
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0079 0.0542 0.0533
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0029 0.0137 0.0647
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Echinococcus granulosus disks large 3 0.0043 0.025 0.0245
Brugia malayi hypothetical protein 0.003 0.0147 0.0143
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0031 0.0282
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0402 0.0393
Brugia malayi Heterochromatin protein 1 0.0072 0.0483 0.048
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Brugia malayi jmjC domain containing protein 0.0063 0.0408 0.0405
Echinococcus granulosus Nuclear hormone receptor HR96 0.0037 0.0202 0.0198
Toxoplasma gondii transporter, cation channel family protein 0.0395 0.312 1
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0152 0.0148
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0201 0.0196
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0349 0.0344
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0063 0.0414 0.0411
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0251 0.064
Echinococcus multilocularis guanylate kinase 0.004 0.0228 0.0223
Schistosoma mansoni loxhd1 0.0041 0.023 0.022
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0201 0.1679
Schistosoma mansoni lipoxygenase 0.0178 0.1351 0.1343
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0095 0.0825
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis amyloid beta A4 protein 0.0071 0.0475 0.047
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.0082 0.0119
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.006 0.0055
Schistosoma mansoni biogenic amine receptor 0.0031 0.0152 0.0142
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0199 0.1156
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.006 0.0055
Echinococcus multilocularis nuclear receptor nhr 48 0.0037 0.0202 0.0198
Echinococcus granulosus allatostatin A receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0152 0.0148
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0091 0.0081
Toxoplasma gondii hypothetical protein 0.0337 0.2648 0.8478
Echinococcus granulosus potassium voltage gated channel protein 0.0058 0.0371 0.0366
Mycobacterium ulcerans hypothetical protein 0.0025 0.0104 0.0783
Schistosoma mansoni hypothetical protein 0.0031 0.0152 0.0142
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0005 0.0012
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0693 0.2773
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0152 0.0142
Brugia malayi hypothetical protein 0.002 0.006 0.0056
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0037 0.0202 0.0198
Loa Loa (eye worm) hypothetical protein 0.0026 0.0111 0.0107
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.006 0.0055
Brugia malayi Carboxylesterase family protein 0.0024 0.0091 0.0087
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.023 0.0225
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0079 0.0542 0.0538
Schistosoma mansoni amyloid beta A4 protein related 0.0071 0.0475 0.0465
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0031 0.0026
Echinococcus multilocularis neuropeptide receptor A26 0.0031 0.0152 0.0148
Echinococcus granulosus chromobox protein 1 0.0072 0.0483 0.0479
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0152 0.0142
Mycobacterium tuberculosis Probable guanylate kinase Gmk 0.004 0.0228 0.1147
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0043 0.025 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0199 0.0506
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0453 0.0934
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0029 0.0137 0.0647
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0029 0.0137 0.0647
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0392 0.0382
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.2351 1
Trypanosoma cruzi hypothetical protein, conserved 0.0219 0.1683 0.3501
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0095 0.0247
Schistosoma mansoni 60S ribosomal protein L21 0.0058 0.0371 0.0361
Schistosoma mansoni regulator of G protein signaling 0.002 0.006 0.005
Trichomonas vaginalis spcc417.12 protein, putative 0.0024 0.0091 0.0232
Trypanosoma cruzi guanylate kinase, putative 0.004 0.0228 0.0465
Trypanosoma brucei guanylate kinase, putative 0.004 0.0228 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0199 0.0506
Schistosoma mansoni ap endonuclease 0.0019 0.0057 0.0047
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0596 0.0592
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0079 0.0542 0.0538
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0062 0.0402 0.0398
Loa Loa (eye worm) carboxylesterase 0.0024 0.0091 0.0086
Brugia malayi PXA domain containing protein 0.002 0.006 0.0056
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.006 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0064 0.0054
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Schistosoma mansoni guanylate kinase 0.004 0.0228 0.0218
Toxoplasma gondii thioredoxin reductase 0.0065 0.0428 0.1319
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0483 0.123
Onchocerca volvulus 0.0031 0.0152 0.0376
Echinococcus granulosus microtubule associated protein 2 0.071 0.5687 0.5685
Echinococcus granulosus carboxylesterase 5A 0.014 0.1036 0.1032
Loa Loa (eye worm) hypothetical protein 0.0337 0.2648 0.2644
Echinococcus multilocularis voltage dependent calcium channel 0.124 1 1
Leishmania major cytochrome p450-like protein 0.0038 0.0211 0.1225
Echinococcus granulosus axis inhibition protein axin 0.002 0.006 0.0055
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0152 0.0148
Schistosoma mansoni hypothetical protein 0.0053 0.0333 0.0323
Loa Loa (eye worm) hypothetical protein 0.0143 0.1064 0.106
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0057 0.0053
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0103 0.02
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.003 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0402 0.0393
Brugia malayi jmjC domain containing protein 0.0061 0.0392 0.0389
Trypanosoma brucei trypanothione reductase 0.0065 0.0428 0.0843
Echinococcus multilocularis serotonin receptor 0.0031 0.0152 0.0148
Wolbachia endosymbiont of Brugia malayi guanylate kinase 0.004 0.0228 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0348 0.0343
Schistosoma mansoni cpg binding protein 0.0035 0.0181 0.0172
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0058 0.0371 0.0366
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0031 0.0055
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0079 0.0542 0.0538
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0201 0.0511
Schistosoma mansoni neuropeptide receptor 0.0031 0.0152 0.0142
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0276 0.0271
Schistosoma mansoni steroid hormone receptor ad4bp 0.0079 0.0542 0.0533
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0276 0.0956
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0179 0.0456
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.006 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0199 0.0506
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Onchocerca volvulus 0.0032 0.0156 0.0384
Brugia malayi hypothetical protein 0.0024 0.0091 0.0087
Brugia malayi hypothetical protein 0.0058 0.0371 0.0367
Toxoplasma gondii histone lysine methyltransferase SET1 0.0068 0.0453 0.1401
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0031 0.0152 0.0376
Loa Loa (eye worm) hydrolase 0.0039 0.0216 0.0212
Echinococcus granulosus voltage gated potassium channel 0.0062 0.0402 0.0398
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0402 0.0393
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0043 0.0125
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.006 0.0055
Loa Loa (eye worm) melatonin receptor type 1A 0.0031 0.0152 0.0148
Brugia malayi 6-phosphofructokinase 0.0112 0.0811 0.0807
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0201 0.1795
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0043 0.0125
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.014 0.1036 0.1032
Onchocerca volvulus 0.0495 0.393 1
Echinococcus multilocularis expressed protein 0.0384 0.303 0.3027
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0408 0.0404
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0079 0.0542 0.0538
Loa Loa (eye worm) ryanodine receptor 0.0058 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0018 0.0042 0.0037
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0145 0.0386
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0058 0.0371 0.0724
Loa Loa (eye worm) hypothetical protein 0.004 0.0228 0.0223
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0031 0.0152 0.0142
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0058 0.0371 0.0367
Leishmania major cytochrome p450-like protein 0.0029 0.0137 0.0787
Schistosoma mansoni nuclear hormone receptor 0.0037 0.0202 0.0193
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0064 0.0059
Entamoeba histolytica hypothetical protein 0.0037 0.0201 0.0628
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0031 0.0152 0.0149
Echinococcus multilocularis conserved hypothetical protein 0.0058 0.0371 0.0366
Echinococcus granulosus 7TM GPCR rhodopsin 0.0031 0.0152 0.0148
Schistosoma mansoni survival motor neuron protein 0.005 0.0303 0.0294
Echinococcus granulosus serine:threonine protein kinase 0.0201 0.1535 0.1531
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0029 0.0137 0.1087
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0022 0.0082 0.1526
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0079 0.0542 0.0539
Brugia malayi putative neuropeptide receptor 0.0031 0.0152 0.0149
Leishmania major protein kinase, putative 0.0014 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0337 0.2648 0.2644
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0029 0.0137 0.0647
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0349 0.0344
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0029 0.0137 0.1087
Onchocerca volvulus Protein ultraspiracle homolog 0.0079 0.0542 0.137
Schistosoma mansoni hypothetical protein 0.0037 0.0201 0.0191
Schistosoma mansoni hypothetical protein 0.0031 0.0152 0.0142
Brugia malayi hypothetical protein 0.0068 0.0452 0.0449
Onchocerca volvulus 0.0031 0.0152 0.0376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0179 0.0456
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0043 0.0125
Schistosoma mansoni hypothetical protein 0.0568 0.453 0.4524
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0693 0.1435
Echinococcus granulosus fmrfamide receptor 0.0031 0.0152 0.0148
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0058 0.0371 0.0367
Schistosoma mansoni inositol monophosphatase 0.0038 0.0209 0.0199
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0098
Brugia malayi ion channel NompC 0.0058 0.0371 0.0367
Schistosoma mansoni nuclear receptor 0.0037 0.0202 0.0193
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0095 0.4046
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0037 0.0202 0.0503
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0199 0.0506
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0079 0.0542 0.0538
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0029 0.0137 0.0647
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0211 0.0429
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0086
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0029 0.0137 0.1087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0152 0.0142
Brugia malayi AKH receptor 0.0031 0.0152 0.0149
Loa Loa (eye worm) calcium channel 0.124 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0152 0.0148
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0079 0.0542 0.0538
Echinococcus granulosus nuclear receptor nhr 48 0.0037 0.0202 0.0198
Onchocerca volvulus 0.0015 0.0023 0.0047
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.0384
Schistosoma mansoni rab6-interacting 0.0041 0.023 0.022
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0031 0.0055
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0408 0.0399
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.012 0.0115
Loa Loa (eye worm) hypothetical protein 0.0091 0.0638 0.0633
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.003 0.0026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0057 0.0108
Echinococcus granulosus voltage gated potassium channel 0.0058 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0086
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0029 0.0137 0.1087
Onchocerca volvulus 0.0031 0.0152 0.0376
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0029 0.0137 0.0647
Echinococcus multilocularis two pore calcium channel protein 2 0.0058 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0086 0.0596 0.0592
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0103 0.0582
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0022 0.0082 0.0343
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0145 0.2889
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0137 0.0276
Schistosoma mansoni zinc finger protein 0.0037 0.0202 0.0193
Onchocerca volvulus 0.0024 0.0091 0.0219
Giardia lamblia Kinase, PLK 0.0097 0.0693 0.2773
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0408 0.2403
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0025 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.0046
Schistosoma mansoni histamine h1 receptor 0.0031 0.0152 0.0142
Trichomonas vaginalis sap-102, putative 0.004 0.0228 0.0579
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.003 0.0039
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0058 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus granulosus nuclear factor of activated T cells 5 0.0153 0.1149 0.1145
Brugia malayi hypothetical protein 0.0168 0.1268 0.1265
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Mycobacterium ulcerans hypothetical protein 0.0037 0.0201 0.1679
Loa Loa (eye worm) hypothetical protein 0.124 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0152 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0276 0.0702
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0031 0.0013
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0201 0.0196
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0811 0.1681
Entamoeba histolytica guanylate kinase, putative 0.004 0.0228 0.0745
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0293 0.0745
Loa Loa (eye worm) hypothetical protein 0.0079 0.0542 0.0538
Trypanosoma cruzi trypanothione reductase, putative 0.0065 0.0428 0.0882
Schistosoma mansoni nuclear receptor nhr-48 0.0037 0.0202 0.0193
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Plasmodium falciparum glutathione reductase 0.0065 0.0428 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0435 0.3439 0.3436
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.014 0.1036 0.1027
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0058 0.0371 0.0367
Echinococcus multilocularis netrin receptor unc 5 0.003 0.0143 0.0138
Loa Loa (eye worm) hypothetical protein 0.002 0.006 0.0055
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0062 0.0402 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.002 0.006 0.0152
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0043 0.0125
Echinococcus granulosus myosin light chain kinase smooth muscle 0.0201 0.1535 0.1531
Brugia malayi nuclear hormone receptor 0.0037 0.0202 0.0199
Loa Loa (eye worm) X11 protein 0.0071 0.0475 0.047
Schistosoma mansoni vesicular amine transporter 0.0062 0.0402 0.0393
Loa Loa (eye worm) hypothetical protein 0.0037 0.0201 0.0196
Schistosoma mansoni hypothetical protein 0.0568 0.453 0.4524
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0031 0.0026
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0005 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0219 0.1683 0.3501
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0179 0.0456
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0029 0.0137 0.0787
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.006 0.005
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0031 0.0021
Onchocerca volvulus Neuropeptide F receptor homolog 0.0031 0.0152 0.0376
Echinococcus multilocularis potassium voltage gated channel protein 0.0062 0.0402 0.0398
Brugia malayi steroid hormone receptor 0.0079 0.0542 0.0539
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0147 0.0296
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0211 0.0206
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0095 0.0696
Schistosoma mansoni mannosidase endo-alpha 0.004 0.0228 0.0218
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0029 0.0137 0.0647
Schistosoma mansoni transient receptor potential channel 0.0058 0.0373 0.0363
Onchocerca volvulus Bile acid receptor homolog 0.0079 0.0542 0.137
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0811 0.4372
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0031 0.0152 0.0149
Echinococcus multilocularis thioredoxin glutathione reductase 0.0065 0.0428 0.0423
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0209 0.0663
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0079 0.0542 0.0539
Echinococcus granulosus g protein coupled receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0079 0.0542 0.0538
Echinococcus granulosus neuropeptide FF receptor 2 0.0031 0.0152 0.0148
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0103 0.0766
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Echinococcus granulosus cytochrome P450 2K1 0.0029 0.0137 0.0132
Chlamydia trachomatis guanylate kinase 0.004 0.0228 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0042 0.0239 0.0234
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0408 0.1257
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0057 0.0052
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0031 0.0152 0.0142
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0811 0.0801
Echinococcus granulosus intermediate filament protein 0.0056 0.0357 0.0352
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0042 0.0239 0.0229
Echinococcus granulosus chromobox protein 1 0.0072 0.0483 0.0479
Brugia malayi Carboxylesterase family protein 0.014 0.1036 0.1033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0178 0.1351 0.1347
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0095 0.2245
Echinococcus multilocularis jun protein 0.0089 0.0621 0.0616
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0209 0.1214
Leishmania major hypothetical protein, unknown function 0.0058 0.0371 0.2181
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0058 0.0371 0.0366
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0086
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0082 0.0161
Echinococcus multilocularis transient receptor potential cation channel 0.0058 0.0371 0.0366
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0058 0.0371 0.0944
Schistosoma mansoni neuroligin 3 (S09 family) 0.0024 0.0091 0.0081
Echinococcus granulosus voltage dependent calcium channel 0.124 1 1
Onchocerca volvulus 0.0031 0.0152 0.0376
Onchocerca volvulus 0.0037 0.0202 0.0503
Schistosoma mansoni chromobox protein 0.0072 0.0483 0.0474
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0103 0.0582
Brugia malayi Inositol-1 0.0038 0.0209 0.0205
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0064 0.006
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0022 0.0082 0.0077
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0031 0.0152 0.0149
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0199 0.0364
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0152 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0221 0.0562
Echinococcus multilocularis transient receptor potential gamma protein 0.0058 0.0371 0.0366
Echinococcus granulosus Nuclear hormone receptor HR96 0.0037 0.0202 0.0198
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0037 0.0202 0.0198
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0811 0.7344
Echinococcus multilocularis potassium large conductance calcium activated 0.0058 0.0371 0.0366
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0082 0.0161
Echinococcus granulosus sodium leak channel non selective protein 0.0058 0.0371 0.0366
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0276 0.0525
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0064 0.0054
Schistosoma mansoni acetylcholinesterase 0.0024 0.0091 0.0081
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0031 0.0152 0.0148
Echinococcus multilocularis short transient receptor potential channel 6 0.0058 0.0371 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0693 0.1764
Schistosoma mansoni opsin-like receptor 0.0031 0.0152 0.0142
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0058 0.0371 0.0933
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0029 0.0073
Echinococcus granulosus jun protein 0.0089 0.0621 0.0616
Echinococcus multilocularis transient receptor potential cation channel 0.0058 0.0371 0.0366
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0062 0.0402 0.0398
Brugia malayi guanylate kinase 0.004 0.0228 0.0224
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.003 0.0145 0.0135
Echinococcus granulosus Ankyrin 0.003 0.0145 0.014
Echinococcus granulosus neuropeptide s receptor 0.0031 0.0152 0.0148
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0811 0.0806
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0143 0.0139
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0152 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.002 0.006 0.0152
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0079 0.0542 0.0538
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0201 0.1679
Echinococcus multilocularis G protein coupled receptor 139 0.0031 0.0152 0.0148
Schistosoma mansoni hypothetical protein 0.0031 0.0152 0.0142
Loa Loa (eye worm) hypothetical protein 0.0058 0.0371 0.0366
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.0371 0.0361
Trypanosoma brucei guanylate kinase, putative 0.004 0.0228 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0179 0.0456
Trichomonas vaginalis mercuric reductase, putative 0.0022 0.0082 0.0209
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0412 0.3645
Schistosoma mansoni transient receptor potential channel 4 0.0058 0.0371 0.0361
Brugia malayi Nuclear hormone receptor E75 0.0037 0.0202 0.0199
Echinococcus granulosus MAGUK p55 subfamily 0.0043 0.025 0.0245
Brugia malayi cation channel family protein 0.0058 0.0371 0.0367
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0047 0.0042
Loa Loa (eye worm) hypothetical protein 0.0062 0.0402 0.0398
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0058 0.0371 0.0366
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0051 0.0765
Brugia malayi Thioredoxin reductase 0.0065 0.0428 0.0424
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0058 0.0371 0.0366
Echinococcus granulosus acetylcholinesterase 0.014 0.1036 0.1032
Loa Loa (eye worm) hypothetical protein 0.0024 0.0091 0.0086
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0568 0.453 0.4527
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0022 0.0082 0.1301
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0617 0.0613
Brugia malayi sulfakinin receptor protein 0.0031 0.0152 0.0149
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.006 0.0055
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0043 0.025 0.0245
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0103 0.0766
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.0412 0.0409
Giardia lamblia GTOR 0.0046 0.0276 0.0956
Echinococcus multilocularis para nitrobenzyl esterase 0.0024 0.0091 0.0086
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0201 0.1
Brugia malayi Carboxylesterase family protein 0.0024 0.0091 0.0087
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0145 0.037
Brugia malayi hypothetical protein 0.0037 0.0202 0.0199
Schistosoma mansoni hypothetical protein 0.003 0.0143 0.0133
Brugia malayi Uncoordinated protein 44 0.003 0.0143 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0064 0.0054
Schistosoma mansoni cpg binding protein 0.0037 0.0198 0.0188
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0211 0.0429
Echinococcus multilocularis sodium leak channel non selective protein 0.0058 0.0371 0.0366
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0058 0.0371 0.0366
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0357 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0226 0.0577
Brugia malayi RE15519p 0.0031 0.0152 0.0149
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0453 0.0448
Loa Loa (eye worm) hypothetical protein 0.0042 0.0239 0.0234
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0453 0.0443
Mycobacterium leprae Conserved hypothetical protein 0.0029 0.0137 0.1211
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.0082 0.0119
Brugia malayi intermediate filament protein 0.0056 0.0357 0.0353
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0693 0.0688
Loa Loa (eye worm) hypothetical protein 0.0042 0.0239 0.0234
Brugia malayi hypothetical protein 0.0042 0.0239 0.0235
Echinococcus multilocularis calcium activated potassium channel 0.0058 0.0375 0.037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Schistosoma mansoni hypothetical protein 0.0072 0.0485 0.0476
Echinococcus multilocularis high voltage activated calcium channel beta 0.0551 0.4387 0.4384
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0022 0.0082 0.1492
Brugia malayi ecdysone receptor 0.0037 0.0202 0.0199
Trichomonas vaginalis glutathione reductase, putative 0.0022 0.0082 0.0209
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0209 0.1752
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0392 0.0387
Leishmania major hypothetical protein, conserved 0.0016 0.003 0.0152
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0029 0.0137 0.1087
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0201 0.0409
Loa Loa (eye worm) hypothetical protein 0.004 0.0228 0.0223
Loa Loa (eye worm) hypothetical protein 0.0031 0.0152 0.0148
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0058 0.0371 0.0361
Entamoeba histolytica hypothetical protein 0.002 0.006 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0408 0.3605
Toxoplasma gondii NADPH-glutathione reductase 0.0022 0.0082 0.0205
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0058 0.0371 0.0366
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0037 0.0202 0.0198
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0251 0.064
Loa Loa (eye worm) hypothetical protein 0.0079 0.0542 0.0538
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0145 0.037
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.006 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0037 0.0202 0.0198
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0103 0.0456
Echinococcus granulosus transient receptor potential gamma protein 0.0058 0.0371 0.0366
Brugia malayi Protein kinase domain containing protein 0.003 0.0147 0.0143
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0058 0.0371 0.2181
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0693 0.0688
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0095 0.0696
Schistosoma mansoni retinoic acid receptor RXR 0.0079 0.0542 0.0533
Mycobacterium ulcerans hypothetical protein 0.0025 0.0103 0.0766
Mycobacterium ulcerans carboxylesterase, LipT 0.0024 0.0091 0.0659
Schistosoma mansoni cytochrome P450 0.0029 0.0137 0.0127

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.5849 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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