Detailed information for compound 1377275

Basic information

Technical information
  • TDR Targets ID: 1377275
  • Name: (E)-N-(2,3-dihydro-1,4-benzodioxin-7-yl)-3-(2 -methoxyphenyl)prop-2-enamide
  • MW: 311.332 | Formula: C18H17NO4
  • H donors: 1 H acceptors: 1 LogP: 2.87 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1/C=C/C(=O)Nc1ccc2c(c1)OCCO2
  • InChi: 1S/C18H17NO4/c1-21-15-5-3-2-4-13(15)6-9-18(20)19-14-7-8-16-17(12-14)23-11-10-22-16/h2-9,12H,10-11H2,1H3,(H,19,20)/b9-6+
  • InChiKey: MEOGKJOTLWVCRS-RMKNXTFCSA-N  


Substructure search Similarity search

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Synonyms

  • N-(2,3-dihydro-1,4-benzodioxin-7-yl)-3-(2-methoxyphenyl)prop-2-enamide
  • N-(2,3-dihydro-1,4-benzodioxin-7-yl)-3-(2-methoxyphenyl)acrylamide
  • (E)-N-(2,3-dihydro-1,4-benzodioxin-7-yl)-3-(2-methoxyphenyl)acrylamide
  • SMR000271780
  • ST5202249
  • ZINC00149631
  • MLS000676773
  • N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(2-methoxyphenyl)acrylamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references
Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog A No references
Homo sapiens RAB9A, member RAS oncogene family Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Plasmodium falciparum ras-related protein Rab-5B RAB9A, member RAS oncogene family 201 aa 165 aa 30.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) protein kinase domain-containing protein 0.0045 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Schistosoma mansoni tensin-related 0.0052 0.0076 0.0096
Trichomonas vaginalis STE family protein kinase 0.0088 0.0437 0.1636
Leishmania major protein kinase, putative 0.0052 0.0074 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.1774 0.2246
Echinococcus multilocularis casein kinase I alpha 0.0111 0.067 0.0716
Echinococcus multilocularis signal transduction protein lnk realted 0.0052 0.0076 0.0081
Trypanosoma brucei NIMA-related protein kinase 0.0052 0.0074 0.026
Trypanosoma cruzi cdc2-related kinase 1 0.0122 0.0774 0.3305
Brugia malayi ribosomal protein S6 kinase alpha 3 0.012 0.0756 0.0813
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.79 1
Plasmodium falciparum calcium-dependent protein kinase 4 0.0103 0.0589 0.5045
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Loa Loa (eye worm) thyroid receptor interactor 0.0106 0.0616 0.0666
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0142 0.0982 0.4196
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0062
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0138 0.0937 0.3658
Schistosoma mansoni tyrosine kinase 0.0565 0.5212 0.6598
Echinococcus multilocularis protein kinase c iota type 0.03 0.2563 0.2738
Brugia malayi serine/threonine-protein kinase PAK 7 0.0238 0.194 0.2094
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.067 0.0848
Brugia malayi Immunoglobulin I-set domain containing protein 0.0454 0.4105 0.4438
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0185 0.1406 0.1502
Schistosoma mansoni protein kinase 0.0238 0.1939 0.2454
Entamoeba histolytica hypothetical protein 0.0391 0.3467 1
Leishmania major casein kinase, putative 0.0111 0.067 0.2856
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0168 0.124 0.124
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0163 0.1189 0.4487
Loa Loa (eye worm) TK protein kinase 0.0045 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0045 0.0005 0.0005
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0342 0.2984 0.3228
Trichomonas vaginalis CK1 family protein kinase 0.0111 0.067 0.2519
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0342 0.2984 0.3224
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0413 0.0523
Onchocerca volvulus 0.0097 0.0524 0.1537
Plasmodium vivax serine/threonine protein kinase, putative 0.0085 0.0407 0.347
Schistosoma mansoni rap gtpase-activating protein 0.0115 0.0706 0.0894
Echinococcus multilocularis rac serine:threonine kinase 0.017 0.1255 0.1341
Brugia malayi Protein kinase domain containing protein 0.0097 0.0524 0.0562
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0259 0.2145 0.2321
Loa Loa (eye worm) hypothetical protein 0.005 0.0059 0.0064
Schistosoma mansoni tensin-related 0.0052 0.0076 0.0096
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0056 0.0114 0.0123
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0982 0.3701
Echinococcus granulosus tyrosine protein kinase 0.0291 0.2472 0.2472
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0413 0.1548
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.1784 0.6742
Leishmania major protein kinase, putative 0.0087 0.0423 0.1795
Brugia malayi MAP kinase sur-1 0.0086 0.0413 0.0442
Toxoplasma gondii casein kinase I 0.0111 0.067 0.261
Plasmodium vivax tyrosine kinase-like protein, putative 0.0083 0.0385 0.3284
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0149 0.1049 0.3015
Brugia malayi Protein kinase domain containing protein 0.0458 0.4146 0.4482
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0084 0.0106
Echinococcus granulosus defective proboscis extension response 0.0074 0.0295 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0472 0.0597
Loa Loa (eye worm) hypothetical protein 0.0286 0.2416 0.2614
Echinococcus multilocularis SHC transforming protein 3 0.0052 0.0076 0.0081
Schistosoma mansoni serine/threonine kinase 0.0222 0.1784 0.2258
Entamoeba histolytica protein kinase, putative 0.0088 0.0437 0.1247
Giardia lamblia Kinase, STE STE20 0.0087 0.0423 0.1795
Schistosoma mansoni vav2 0.0104 0.0598 0.0757
Giardia lamblia Aurora kinase 0.0149 0.1049 0.4484
Echinococcus granulosus retinal guanylyl cyclase 2 0.0045 0.0005 0.0005
Brugia malayi Serine/threonine-protein kinase SULU 0.0228 0.1838 0.1984
Toxoplasma gondii AGC kinase 0.0299 0.2552 1
Echinococcus granulosus protein kinase c epsilon type 0.0216 0.1723 0.1723
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0054 0.0101 0.0365
Entamoeba histolytica protein kinase, putative 0.0072 0.0281 0.0797
Schistosoma mansoni cell adhesion molecule 0.0105 0.0605 0.0766
Echinococcus multilocularis Ankyrin 0.0068 0.0238 0.0254
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0157 0.1133 0.1225
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0052 0.0076 0.0081
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0127 0.0829 0.0886
Loa Loa (eye worm) hypothetical protein 0.0068 0.0237 0.0256
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0157 0.1133 0.4845
Trypanosoma cruzi aurora B kinase, putative 0.0149 0.1049 0.4484
Brugia malayi SH2 domain containing protein 0.0052 0.0076 0.0077
Schistosoma mansoni protein kinase 0.0045 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0105 0.0605 0.0766
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0982 0.3701
Echinococcus granulosus SH2 motif 0.0052 0.0076 0.0076
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0068 0.0072
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0074 0.0295 0.0373
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0088 0.0437 0.0437
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0405 0.3608 0.3903
Loa Loa (eye worm) AGC/NDR protein kinase 0.0172 0.128 0.1385
Echinococcus multilocularis mitogen activated protein kinase 0.0086 0.0413 0.0442
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0582 0.2186
Echinococcus multilocularis tensin 0.0052 0.0076 0.0081
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0124 0.0803 0.1016
Onchocerca volvulus Serine\/threonine kinase homolog 0.0168 0.124 0.3636
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0052 0.0076 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0005 0.0006
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0056 0.0114 0.0118
Schistosoma mansoni protein kinase 0.0149 0.1049 0.1327
Loa Loa (eye worm) hypothetical protein 0.009 0.0456 0.0493
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0115 0.0706 0.0706
Brugia malayi Protein kinase domain containing protein 0.0097 0.0524 0.0562
Echinococcus multilocularis SH2 motif 0.0052 0.0076 0.0081
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0582 0.2186
Echinococcus granulosus tyrosine kinase 0.0157 0.1128 0.1128
Trypanosoma cruzi casein kinase, putative 0.0111 0.067 0.2856
Echinococcus multilocularis death associated protein kinase 1 0.0871 0.828 0.8845
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0045 0.0005 0.0005
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0052 0.0076 0.0081
Brugia malayi casein kinase 1, delta 0.0111 0.067 0.072
Trypanosoma cruzi rac serine-threonine kinase, putative 0.017 0.1255 0.5372
Onchocerca volvulus 0.0066 0.0215 0.0632
Echinococcus granulosus N chimaerin 0.0095 0.0506 0.0506
Trichomonas vaginalis CK1 family protein kinase 0.0111 0.067 0.2519
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0185 0.1406 0.1502
Trypanosoma brucei protein kinase, putative 0.0132 0.0876 0.3299
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Trypanosoma cruzi Protein kinase B 0.017 0.1255 0.5372
Echinococcus granulosus cyclin dependent kinase 1 0.0122 0.0774 0.0774
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0086 0.0413 0.1755
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0045 0.0005 0.0006
Brugia malayi hypothetical protein 0.0115 0.0706 0.0759
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0086 0.0413 0.1603
Loa Loa (eye worm) TK/RYK protein kinase 0.0045 0.0005 0.0005
Echinococcus multilocularis FL cytokine receptor 0.0045 0.0005 0.0005
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0052 0.0076 0.0081
Brugia malayi SH2 domain containing protein 0.0052 0.0076 0.0077
Loa Loa (eye worm) hypothetical protein 0.0182 0.1384 0.1497
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0072 0.0281 0.03
Entamoeba histolytica protein kinase, putative 0.0132 0.0876 0.2515
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0238 0.1943 0.1943
Trypanosoma cruzi casein kinase, putative 0.0111 0.067 0.2856
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0582 0.2186
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.0582 0.1666
Trichomonas vaginalis CMGC family protein kinase 0.0122 0.0774 0.2915
Echinococcus granulosus dual specificity 0.0142 0.0982 0.0982
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0982 0.3701
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0132 0.0876 0.0936
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0045 0.0005 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.0078 0.0339 0.0966
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0083 0.039 0.0422
Entamoeba histolytica SH2 domain containing protein 0.0052 0.0076 0.0205
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0091 0.0472 0.2005
Echinococcus granulosus protein kinase c iota type 0.03 0.2563 0.2563
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0582 0.2186
Onchocerca volvulus 0.0052 0.0076 0.0223
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0157 0.1133 0.4845
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0408 0.3646 0.3646
Entamoeba histolytica tyrosin kinase, putative 0.0048 0.0038 0.0095
Echinococcus granulosus titin 0.0069 0.0245 0.0245
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0064 0.0198 0.0198
Brugia malayi Protein kinase domain containing protein 0.0117 0.0726 0.078
Echinococcus granulosus signal transduction protein lnk realted 0.0052 0.0076 0.0076
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0508 0.4638 0.4955
Trypanosoma cruzi NIMA-related kinase, putative 0.0052 0.0074 0.0295
Echinococcus granulosus titin 0.0069 0.0245 0.0245
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0045 0.0005 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0044 0.0042
Echinococcus multilocularis dual specificity 0.0142 0.0982 0.1049
Schistosoma mansoni protein kinase 0.0272 0.2277 0.2882
Loa Loa (eye worm) hypothetical protein 0.0186 0.1415 0.1531
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.1133 0.1434
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.1133 0.4273
Brugia malayi probable protein kinase 0.0272 0.2277 0.246
Brugia malayi phosphoinositide-dependent protein kinase I 0.0083 0.039 0.0417
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Entamoeba histolytica serine/threonine protein kinase, putative 0.0052 0.0074 0.0199
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.005 0.0059 0.0059
Onchocerca volvulus 0.0045 0.0005 0.0015
Plasmodium falciparum glycogen synthase kinase 3 0.0132 0.0876 0.7517
Loa Loa (eye worm) AGC/PKA protein kinase 0.0116 0.0715 0.0773
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0074 0.026
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0115 0.0706 0.0894
Leishmania major protein kinase A catalytic subunit isoform 1 0.0116 0.0715 0.3049
Schistosoma mansoni shc transforming protein 0.0052 0.0076 0.0096
Echinococcus granulosus tensin 0.0052 0.0076 0.0076
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0413 0.1548
Brugia malayi tRNA modification GTPase TrmE family protein 0.0052 0.0076 0.0077
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0091 0.0472 0.2005
Brugia malayi Egg laying defective protein 4 0.0138 0.0937 0.1009
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0475 0.0602
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0524 0.0567
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.2176 0.2754
Schistosoma mansoni GTPase activating protein 0.0052 0.0076 0.0096
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0185 0.1406 0.1502
Schistosoma mansoni protein kinase 0.0045 0.0006 0.0008
Schistosoma mansoni ankyrin 23/unc44 0.0068 0.0237 0.0299
Brugia malayi hypothetical protein 0.0182 0.1384 0.1492
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.0747 0.0803
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0052 0.0074 0.0593
Echinococcus granulosus casein kinase ii subunit alpha 0.0102 0.0582 0.0582
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.2416 0.2581
Loa Loa (eye worm) hypothetical protein 0.0047 0.0028 0.0031
Echinococcus multilocularis serine:threonine protein kinase N2 0.0133 0.0891 0.0951
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0052 0.0074 0.026
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.1838 0.2327
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.2333 0.882
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0052 0.0074 0.026
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0086 0.0413 0.1755
Entamoeba histolytica protein kinase , putative 0.0149 0.1049 0.3015
Entamoeba histolytica protein kinase, putative 0.0142 0.0982 0.2821
Echinococcus multilocularis 0.0124 0.0798 0.0853
Trypanosoma cruzi cdc2-related kinase 3 0.0122 0.0774 0.3305
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0054 0.0101 0.0365
Onchocerca volvulus 0.0045 0.0005 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0114 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0407 0.0515
Echinococcus granulosus tyrosine protein kinase csk 0.0045 0.0005 0.0005
Echinococcus multilocularis protein kinase 0.0045 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0142 0.0982 0.1057
Entamoeba histolytica protein kinase, putative 0.0299 0.2552 0.7357
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.0747 0.0747
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.128 0.162
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0362 0.3179 0.4024
Schistosoma mansoni protein kinase 0.0157 0.1128 0.1427
Trichomonas vaginalis AGC family protein kinase 0.0202 0.1582 0.5976
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0059 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0074 0.026
Loa Loa (eye worm) TK protein kinase 0.0105 0.0608 0.0658
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0045 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0364 0.3197 0.3459
Loa Loa (eye worm) hypothetical protein 0.0074 0.0298 0.0322
Loa Loa (eye worm) hypothetical protein 0.0108 0.0636 0.0688
Trichomonas vaginalis AGC family protein kinase 0.0083 0.039 0.146
Echinococcus multilocularis tensin 0.0052 0.0076 0.0081
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Entamoeba histolytica casein kinase, putative 0.0102 0.0582 0.1666
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0075 0.0312 0.0337
Brugia malayi Protein kinase domain containing protein 0.0122 0.0774 0.0833
Schistosoma mansoni protein kinase 0.0445 0.4016 0.5084
Leishmania major protein kinase A catalytic subunit isoform 2 0.0116 0.0715 0.3049
Echinococcus multilocularis calcium activated potassium channel 0.0138 0.0939 0.1003
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0068 0.0238 0.0301
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0059 0.0059
Onchocerca volvulus 0.0045 0.0005 0.0015
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0259 0.2145 0.2291
Leishmania major protein kinase, putative 0.0078 0.0339 0.1436
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0103 0.0589 0.2215
Brugia malayi integrin-linked kinase 0.0045 0.0005 0.000000024002
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0157 0.1128 0.1128
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0045 0.0005 0.0005
Echinococcus multilocularis CDC7 cell division cycle 7 0.0092 0.0475 0.0508
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0138 0.0937 0.1001
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0376 0.3325 0.3552
Trypanosoma brucei protein kinase, putative 0.0086 0.0413 0.1548
Loa Loa (eye worm) hypothetical protein 0.0092 0.0475 0.0514
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0125 0.081 0.3049
Brugia malayi map kinase activated protein kinase protein 2 0.0405 0.3608 0.39
Trichomonas vaginalis CAMK family protein kinase 0.0118 0.0736 0.277
Loa Loa (eye worm) hypothetical protein 0.0108 0.0636 0.0688
Echinococcus granulosus hypothetical protein 0.0124 0.0798 0.0798
Echinococcus granulosus twitchin 0.0126 0.0822 0.0822
Trichomonas vaginalis STE family protein kinase 0.0087 0.0423 0.1584
Loa Loa (eye worm) AGC/PKN protein kinase 0.0305 0.2614 0.2828
Schistosoma mansoni protein kinase 0.0445 0.4016 0.5084
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Brugia malayi SH2 domain containing protein 0.0052 0.0076 0.0077
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0116 0.0715 0.0715
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Toxoplasma gondii CMGC kinase, CK2 family 0.0102 0.0582 0.2265
Leishmania major casein kinase II, putative 0.0102 0.0582 0.2479
Echinococcus granulosus roundabout 2 0.0124 0.0797 0.0797
Entamoeba histolytica PH domain containing protein kinase, putative 0.0125 0.0807 0.2316
Onchocerca volvulus Serine\/threonine kinase homolog 0.0277 0.2333 0.684
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0045 0.0005 0.0005
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0399 0.3547 0.3547
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0045 0.0005 0.0005
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0088 0.0437 0.0437
Entamoeba histolytica protein kinase, putative 0.0308 0.2644 0.7623
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0045 0.0005 0.0006
Loa Loa (eye worm) TK/DDR protein kinase 0.0045 0.0005 0.0005
Entamoeba histolytica PH domain containing protein kinase, putative 0.017 0.1255 0.3612
Brugia malayi Doublecortin family protein 0.0155 0.1104 0.1189
Echinococcus multilocularis tyrosine protein kinase Abl 0.0124 0.0803 0.0857
Brugia malayi Protein kinase domain containing protein 0.0199 0.1545 0.1667
Echinococcus granulosus epidermal growth factor receptor 0.0625 0.5818 0.5818
Echinococcus granulosus nervana 2 0.0127 0.0829 0.0829
Loa Loa (eye worm) hypothetical protein 0.009 0.0456 0.0493
Brugia malayi hypothetical protein 0.009 0.0456 0.0488
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.005 0.0059 0.0064
Entamoeba histolytica protein kinase domain containing protein 0.0208 0.1637 0.4713
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0524 0.0567
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0616 0.5725 0.6194
Schistosoma mansoni netrin receptor unc5 0.0083 0.0386 0.0488
Onchocerca volvulus 0.0045 0.0005 0.0015
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0005 0.000000084018
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.0589 0.063
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.2333 0.882
Brugia malayi cell division control protein 2 homolog 0.0122 0.0774 0.0833
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.005 0.0059 0.0064
Plasmodium falciparum calcium-dependent protein kinase 2 0.0103 0.0589 0.5045
Schistosoma mansoni tyrosine kinase 0.0367 0.3228 0.4086
Schistosoma mansoni growth factor receptor-bound protein 0.008 0.0354 0.0449
Loa Loa (eye worm) hypothetical protein 0.0315 0.2708 0.2929
Echinococcus granulosus casein kinase I gamma 0.0219 0.1746 0.1746
Plasmodium vivax casein kinase 1, putative 0.0111 0.067 0.574
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0074 0.026
Echinococcus multilocularis mitogen activated protein kinase 3 0.0086 0.0413 0.0442
Echinococcus multilocularis expressed conserved protein 0.0138 0.0937 0.1001
Brugia malayi Pleckstrin Homology Domain 0.0052 0.0079 0.008
Brugia malayi Protein kinase c protein 2 0.0118 0.0742 0.0798
Echinococcus granulosus mitogen activated protein kinase 11 0.0163 0.1189 0.1189
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.3608 0.4566
Brugia malayi Protein kinase domain containing protein 0.0092 0.0475 0.0509
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0045 0.0005 0.0006
Echinococcus multilocularis epidermal growth factor receptor 0.0411 0.3676 0.3927
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.005 0.0059 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.1746 0.221
Echinococcus multilocularis rho associated protein kinase 0.0334 0.2897 0.3095
Echinococcus multilocularis epidermal growth factor receptor 0.0625 0.5818 0.6215
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0111 0.067 0.0725
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0097 0.0524 0.15
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0074 0.0093
Schistosoma mansoni protein kinase 0.0066 0.0214 0.0271
Schistosoma mansoni ste20-related kinase 0.021 0.1662 0.2104
Loa Loa (eye worm) hypothetical protein 0.0364 0.3197 0.3459
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0052 0.0076 0.0081
Loa Loa (eye worm) hypothetical protein 0.0089 0.0444 0.048
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0103 0.0589 0.5045
Mycobacterium ulcerans hypothetical protein 0.0104 0.0602 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0937 0.1186
Schistosoma mansoni hypothetical protein 0.0058 0.014 0.0177
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0149 0.1049 0.3015
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Entamoeba histolytica protein kinase domain containing protein 0.0125 0.081 0.2324
Onchocerca volvulus 0.0097 0.0524 0.1537
Loa Loa (eye worm) TK/ROR protein kinase 0.0064 0.0198 0.0214
Echinococcus granulosus neuroglian 0.005 0.0059 0.0059
Brugia malayi serine/threonine kinase 12 0.0149 0.1049 0.113
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.2416 0.2416
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0616 0.5725 0.6194
Echinococcus granulosus kinase suppressor of Ras 1 0.0045 0.0005 0.0005
Brugia malayi SH2 domain containing protein 0.0097 0.0524 0.0562
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2644 1
Echinococcus multilocularis twitchin 0.0053 0.0084 0.0089
Loa Loa (eye worm) TK/EPH protein kinase 0.0129 0.0844 0.0913
Schistosoma mansoni tyrosine kinase 0.0185 0.1406 0.178
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0982 0.3701
Brugia malayi cytokine inducible SH2-containing protein 5 0.0052 0.0076 0.0077
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0157 0.1133 0.4427
Loa Loa (eye worm) TK/ABL protein kinase 0.0097 0.0524 0.0567
Entamoeba histolytica protein kinase, putative 0.0045 0.0008 0.0009
Echinococcus multilocularis tyrosine protein kinase csk 0.0045 0.0005 0.0005
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0115 0.0706 0.2658
Plasmodium vivax protein kinase Crk2 0.0122 0.0774 0.6641
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0185 0.1406 0.1502
Entamoeba histolytica hypothetical protein 0.0045 0.0008 0.0009
Onchocerca volvulus 0.0058 0.014 0.041
Echinococcus multilocularis dual specificity 0.0142 0.0982 0.1049
Entamoeba histolytica protein kinase, putative 0.0075 0.0306 0.0869
Plasmodium falciparum serine/threonine protein kinase KIN 0.0091 0.0472 0.4029
Schistosoma mansoni ephrin receptor 0.0111 0.0664 0.084
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Loa Loa (eye worm) hypothetical protein 0.0119 0.0747 0.0808
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0056 0.0114 0.0469
Plasmodium falciparum NIMA related kinase 4 0.0052 0.0074 0.0593
Schistosoma mansoni tensin 0.0052 0.0076 0.0096
Loa Loa (eye worm) TK/ACK protein kinase 0.0045 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.049 0.4459 0.5644
Echinococcus multilocularis tyrosine protein kinase shark 0.0316 0.2722 0.2908
Schistosoma mansoni tyrosine kinase 0.0411 0.3676 0.4654
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0044 0.0047
Loa Loa (eye worm) TK protein kinase 0.0045 0.0005 0.0005
Echinococcus multilocularis nervana 2 0.0127 0.0829 0.0886
Loa Loa (eye worm) SRC-1 0.0185 0.1406 0.1521
Onchocerca volvulus 0.0052 0.0076 0.0223
Plasmodium falciparum cGMP-dependent protein kinase 0.0138 0.0937 0.8043
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0086 0.0413 0.1755
Entamoeba histolytica protein kinase, putative 0.0172 0.128 0.3682
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Brugia malayi Hr1 repeat family protein 0.0305 0.2614 0.2824
Echinococcus multilocularis hypothetical protein 0.0105 0.0605 0.0646
Brugia malayi Protein kinase domain containing protein 0.0101 0.0571 0.0613
Plasmodium vivax serine/threonine kinase-1, putative 0.0157 0.1133 0.9735
Echinococcus granulosus suppressor of cytokine signaling 7 0.0052 0.0076 0.0076
Loa Loa (eye worm) TK protein kinase 0.0157 0.1128 0.122
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0117 0.0726 0.0785
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0116 0.0715 0.3049
Brugia malayi Variant SH3 domain containing protein 0.008 0.0354 0.0378
Trichomonas vaginalis AGC family protein kinase 0.0149 0.1049 0.3955
Echinococcus granulosus serine:threonine protein kinase 0.0117 0.0726 0.0726
Toxoplasma gondii NEK kinase 0.0052 0.0074 0.027
Brugia malayi protein-tyrosine kinase 0.0157 0.1128 0.1215
Onchocerca volvulus 0.0182 0.1384 0.4058
Loa Loa (eye worm) hypothetical protein 0.0199 0.1549 0.1675
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0524 0.0567
Echinococcus granulosus roundabout 2 0.005 0.0059 0.0059
Schistosoma mansoni protein kinase 0.0045 0.0005 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0005 0.000000084018
Onchocerca volvulus 0.0045 0.0005 0.0015
Echinococcus granulosus calcium dependent protein kinase 0.007 0.0255 0.0255
Schistosoma mansoni tensin 0.0052 0.0076 0.0096
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0062 0.0181 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0939 0.1189
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0115 0.0706 0.0755
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0068 0.0073
Echinococcus granulosus serine/threonine protein kinase 0.017 0.1255 0.1255
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0852 0.321
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.124 0.157
Trichomonas vaginalis STE family protein kinase 0.0052 0.0074 0.026
Echinococcus granulosus ephrin type A receptor 4 A 0.0111 0.0664 0.0664
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0116 0.0715 0.6127
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0238 0.1939 0.2071
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0068 0.0068
Echinococcus granulosus neuroglian 0.0093 0.0487 0.0487
Echinococcus granulosus roundabout 2 0.005 0.0059 0.0059
Loa Loa (eye worm) SH2 domain-containing protein 0.0052 0.0076 0.0082
Brugia malayi STE20-like kinase MST 0.0263 0.2194 0.237
Echinococcus granulosus growth factor receptor bound protein 2 0.0082 0.0375 0.0375
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0045 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase 0.0117 0.0726 0.0726
Schistosoma mansoni tyrosine kinase 0.0185 0.1406 0.178
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0163 0.1189 0.1286
Entamoeba histolytica protein kinase, putative 0.0045 0.0005 0.000000064046
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0052 0.0076 0.0096
Plasmodium falciparum calcium-dependent protein kinase 3 0.0103 0.0589 0.5045
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Brugia malayi hypothetical protein 0.0058 0.0137 0.0143
Entamoeba histolytica cell division protein kinase 2, putative 0.0122 0.0774 0.2222
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0064 0.0193 0.0714
Entamoeba histolytica protein kinase, putative 0.0105 0.0608 0.1743
Plasmodium vivax unspecified product 0.0102 0.0582 0.498
Schistosoma mansoni hypothetical protein 0.0105 0.0605 0.0766
Echinococcus multilocularis SH2 motif 0.0052 0.0076 0.0081
Schistosoma mansoni tyrosine kinase 0.0458 0.4146 0.5248
Onchocerca volvulus 0.0097 0.0524 0.1537
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0047 0.0026 0.0027
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0116 0.0715 0.0764
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0116 0.0715 0.3049
Entamoeba histolytica hypothetical protein 0.0045 0.0008 0.0009
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0103 0.0589 0.0638
Echinococcus multilocularis receptor type guanylyl cyclase 0.0045 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0064 0.0198 0.0211
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0157 0.1133 0.4845
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0142 0.0982 0.4196
Echinococcus granulosus mitogen activated protein kinase 3 0.0086 0.0413 0.0413
Echinococcus multilocularis cyclin dependent kinase 1 0.0122 0.0774 0.0827
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.016 0.1163 0.1243
Brugia malayi protein kinase C3,putative 0.0162 0.1174 0.1266
Entamoeba histolytica protein kinase domain containing protein 0.0142 0.0982 0.2821
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Loa Loa (eye worm) hypothetical protein 0.0115 0.0706 0.0764
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0095 0.0506 0.0548
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0122 0.0774 0.0838
Schistosoma mansoni ephrin receptor 0.0061 0.0166 0.021
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0114 0.07 0.0748
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0088 0.0437 0.0437
Echinococcus multilocularis tyrosine protein kinase HCK 0.0105 0.0608 0.065
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.2614 0.3308
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0052 0.0074 0.0593
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.008 0.0354 0.0449
Brugia malayi intracellular kinase 0.0132 0.0876 0.0943
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0411 0.3676 0.3676
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0185 0.1406 0.1502
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0524 0.0567
Onchocerca volvulus 0.0069 0.0245 0.0718
Loa Loa (eye worm) AUR protein kinase 0.0149 0.1049 0.1135
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0172 0.128 0.128
Echinococcus multilocularis Immunoglobulin 0.0074 0.0295 0.0315
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.019 0.1463 0.1579
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0582 0.2186
Schistosoma mansoni serine/threonine RGC 0.0045 0.0005 0.0006
Echinococcus multilocularis casein kinase I alpha 0.0111 0.067 0.0716
Brugia malayi SH2 domain containing protein 0.0052 0.0076 0.0077
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0056 0.0114 0.0414
Trichomonas vaginalis AGC family protein kinase 0.0193 0.149 0.5627
Onchocerca volvulus 0.0097 0.0524 0.1537
Brugia malayi Protein kinase domain containing protein 0.0222 0.1784 0.1926
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0103 0.0589 0.0589
Loa Loa (eye worm) hypothetical protein 0.0147 0.1026 0.111
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0163 0.1189 0.5087
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0054 0.0101 0.0365
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0052 0.0074 0.0295
Echinococcus granulosus Protein kinase C brain isozyme 0.0257 0.2131 0.2131
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Echinococcus multilocularis c src tyrosine kinase 0.0124 0.0803 0.0857
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0087 0.0423 0.1795
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0241 0.197 0.2104
Giardia lamblia Kinase, CMGC CK2 0.0102 0.0582 0.2479
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0168 0.1237 0.1338
Echinococcus granulosus calcium activated potassium channel 0.0138 0.0939 0.0939
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0045 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.1637 0.2072
Echinococcus multilocularis tyrosine protein kinase csk 0.0045 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase pr2 0.0045 0.0005 0.0005
Leishmania major protein kinase, putative 0.0103 0.0589 0.2511
Plasmodium falciparum casein kinase 2, alpha subunit 0.0102 0.0582 0.498
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0115 0.0706 0.3014
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Echinococcus granulosus tyrosine protein kinase Fyn 0.0185 0.1406 0.1406
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0085 0.0407 0.1523
Loa Loa (eye worm) TK/EGFR protein kinase 0.0625 0.5818 0.6295
Echinococcus multilocularis casein kinase I gamma 0.0219 0.1746 0.1865
Onchocerca volvulus 0.0052 0.0076 0.0223
Loa Loa (eye worm) TK protein kinase 0.0045 0.0005 0.0005
Echinococcus multilocularis netrin receptor unc 5 0.0083 0.0386 0.0412
Echinococcus granulosus tyrosine protein kinase Srms 0.0516 0.4719 0.4719
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0163 0.1189 0.5087
Trypanosoma brucei cdc2-related kinase 3 0.0122 0.0774 0.2915
Brugia malayi serine/threonine protein kinase 6 0.0149 0.1049 0.113
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.2333 0.882
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0005 0.0005
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0149 0.1049 0.1049
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0589 0.0746
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0376 0.3325 0.3598
Echinococcus multilocularis casein kinase i 0.0111 0.067 0.0716
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.0747 0.2144
Echinococcus multilocularis PAK box P21 Rho binding 0.0066 0.0214 0.0228
Echinococcus granulosus protein kinase 0.0157 0.1128 0.1128
Echinococcus granulosus cyclin dependent kinase 5 0.0122 0.0774 0.0774
Trichomonas vaginalis CAMK family protein kinase 0.0117 0.0726 0.2732
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0257 0.2131 0.2276
Echinococcus granulosus dual specificity 0.0142 0.0982 0.0982
Giardia lamblia Kinase, CK1 Casein kinase 0.0111 0.067 0.2856
Schistosoma mansoni patched 1 0.0051 0.0068 0.0085
Echinococcus multilocularis geminin 0.0205 0.1605 0.1715
Giardia lamblia Kinase, CMGC CDK 0.0122 0.0774 0.3305
Brugia malayi Protein kinase domain containing protein 0.0967 0.9243 1
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0172 0.128 0.128
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.081 0.1025
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0068 0.0237 0.0256
Toxoplasma gondii AGC kinase 0.0116 0.0715 0.2787
Loa Loa (eye worm) TK protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0058 0.0137 0.0149
Schistosoma mansoni protein kinase 0.0088 0.0437 0.0553
Giardia lamblia Kinase, AGC PKA 0.016 0.1163 0.4977
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0277 0.2333 0.2524
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0052 0.0076 0.0077
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0087 0.0423 0.1584
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0132 0.0876 0.0947
Plasmodium falciparum casein kinase 1 0.0111 0.067 0.574
Brugia malayi hypothetical protein 0.0286 0.2416 0.261
Loa Loa (eye worm) serine/threonine protein kinase 0.0045 0.0005 0.0005
Echinococcus granulosus casein kinase I delta 0.0111 0.067 0.067
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0091 0.0472 0.4029
Schistosoma mansoni vesicular amine transporter 0.0074 0.0295 0.0373
Echinococcus multilocularis casein kinase I alpha 0.0111 0.067 0.0716
Loa Loa (eye worm) TK/FAK protein kinase 0.0571 0.5274 0.5706
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0118 0.0736 0.0786
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0045 0.0005 0.000000084018
Brugia malayi STAT protein, DNA binding domain containing protein 0.0052 0.0076 0.0077
Toxoplasma gondii histone kinase SNF1, putative 0.0091 0.0472 0.1832
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.016 0.1156 0.4361
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0045 0.0005 0.0005
Schistosoma mansoni survival motor neuron protein 0.0058 0.014 0.0177
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0876 0.3299
Brugia malayi Protein kinase domain containing protein 0.0083 0.039 0.0417
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0045 0.0005 0.0015
Brugia malayi Protein kinase domain containing protein 0.0125 0.081 0.0871
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0068 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0339 0.1436
Entamoeba histolytica cell division protein kinase 2, putative 0.0122 0.0774 0.2222
Echinococcus granulosus tyrosine protein kinase Lyn 0.0218 0.174 0.174
Brugia malayi Protein kinase domain containing protein 0.0291 0.2472 0.267
Trypanosoma brucei SNF1-related protein kinases, putative 0.0091 0.0472 0.1769
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0132 0.0876 0.3741
Brugia malayi Temporarily assigned gene name protein 59 0.0115 0.0706 0.0759
Loa Loa (eye worm) hypothetical protein 0.0103 0.0589 0.0638
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2644 1
Giardia lamblia Kinase, CDC7 0.0092 0.0475 0.2021
Loa Loa (eye worm) hypothetical protein 0.0238 0.1943 0.2102
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0454 0.4105 0.4441
Entamoeba histolytica hypothetical protein 0.0045 0.0008 0.0009
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0185 0.1406 0.1406
Echinococcus multilocularis roundabout 2 0.005 0.0059 0.0064
Echinococcus granulosus retinal guanylyl cyclase 2 0.0045 0.0005 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.0747 0.0798
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0017 0.0045
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Echinococcus granulosus casein kinase I delta 0.0111 0.067 0.067
Echinococcus multilocularis protein kinase c epsilon type 0.0216 0.1723 0.1841
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0052 0.0074 0.0295
Trichomonas vaginalis TK family protein kinase 0.0046 0.0017 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0413 0.1548
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0085 0.0407 0.1727
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0116 0.0715 0.2787
Loa Loa (eye worm) hypothetical protein 0.006 0.0159 0.0173
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0139 0.0953 0.372
Entamoeba histolytica PH domain containing protein kinase, putative 0.0125 0.0807 0.2316
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0072 0.0281 0.03
Echinococcus granulosus Immunoglobulin 0.0074 0.0295 0.0295
Trichomonas vaginalis CK1 family protein kinase 0.0111 0.067 0.2519
Loa Loa (eye worm) hypothetical protein 0.0058 0.0137 0.0149
Echinococcus multilocularis 0.0157 0.1128 0.1204
Loa Loa (eye worm) SH2 domain-containing protein 0.0052 0.0076 0.0082
Onchocerca volvulus 0.0052 0.0076 0.0223
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.2333 0.882
Brugia malayi serine/threonine-protein kinase 6 0.0149 0.1049 0.113
Brugia malayi Protein kinase domain containing protein 0.0376 0.3325 0.3594
Onchocerca volvulus 0.03 0.2563 0.7515
Echinococcus granulosus serine:threonine kinase SAD 1 0.0091 0.0472 0.0472
Trichomonas vaginalis AGC family protein kinase 0.0172 0.128 0.483
Echinococcus granulosus tyrosine protein kinase Src42A 0.0114 0.07 0.07
Loa Loa (eye worm) AGC/PKA protein kinase 0.0116 0.0715 0.0773
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0208 0.1637 0.1771
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.79 0.8439
Echinococcus multilocularis neuroglian 0.0093 0.0487 0.0521
Trypanosoma cruzi polo-like protein kinase, putative 0.0277 0.2333 1
Schistosoma mansoni serine/threonine-protein kinase 0.017 0.1255 0.1589
Giardia lamblia Kinase, NEK 0.0052 0.0074 0.0295
Echinococcus multilocularis mitogen activated protein kinase 11 0.0163 0.1189 0.127
Brugia malayi Protein kinase domain containing protein 0.0085 0.0407 0.0435
Brugia malayi Protein kinase domain containing protein 0.0097 0.0524 0.0562
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0122 0.0774 0.3305
Plasmodium falciparum serine/threonine protein kinase 0.0085 0.0407 0.347
Trypanosoma brucei Casein kinase II 0.0102 0.0582 0.2186
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0116 0.0715 0.6127
Echinococcus multilocularis mitogen activated protein kinase 11 0.0163 0.1189 0.127
Schistosoma mansoni serine/threonine protein kinase 0.0257 0.2131 0.2697
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0238 0.194 0.2099
Loa Loa (eye worm) hypothetical protein 0.0246 0.2024 0.2189
Plasmodium vivax calcium-dependent protein kinase, putative 0.0103 0.0589 0.5045
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0116 0.0715 0.0764
Loa Loa (eye worm) hypothetical protein 0.0116 0.0715 0.0773
Loa Loa (eye worm) hypothetical protein 0.0074 0.0295 0.0319
Brugia malayi Uncoordinated protein 44 0.0068 0.0237 0.0251
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0475 0.1783
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase Blk 0.0157 0.1128 0.1204
Loa Loa (eye worm) hypothetical protein 0.019 0.1457 0.1576
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0206 0.1617 0.1727
Leishmania major protein kinase, putative 0.0149 0.1049 0.4484
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0939 0.1189
Brugia malayi SH2 domain containing protein 0.0408 0.3646 0.3941
Trichomonas vaginalis STE family protein kinase 0.0088 0.0437 0.1636
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0082 0.038 0.038
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Brugia malayi Kinase associated domain 1 family protein 0.0105 0.0605 0.0649
Onchocerca volvulus 0.0199 0.1549 0.4541
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0103 0.0589 0.0633
Trichomonas vaginalis AGC family protein kinase 0.0149 0.1049 0.3955
Echinococcus multilocularis mitogen activated protein kinase 14 0.0163 0.1189 0.127
Schistosoma mansoni protein kinase 0.0102 0.0582 0.0737
Schistosoma mansoni tyrosine protein kinase 0.0045 0.0005 0.0006
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0277 0.2333 0.2492
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.1049 0.3015
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0163 0.1189 0.5087
Echinococcus granulosus expressed conserved protein 0.0112 0.0675 0.0675
Trichomonas vaginalis AGC family protein kinase 0.0116 0.0715 0.269
Echinococcus granulosus microtubule associated protein 2 0.0833 0.79 0.79
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0052 0.0076 0.0076
Brugia malayi hypothetical protein 0.0097 0.0524 0.0562
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0249 0.2045 0.2184
Entamoeba histolytica protein kinase, putative 0.0085 0.041 0.1171
Loa Loa (eye worm) CAMK/PKD protein kinase 0.018 0.1361 0.1472
Echinococcus granulosus protein tyrosine kinase 0.0565 0.5212 0.5212
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Schistosoma mansoni atypical protein kinase C 0.0307 0.2626 0.3323
Plasmodium falciparum NIMA related kinase 2 0.0052 0.0074 0.0593
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0083 0.039 0.039
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0982 0.3701
Brugia malayi Protein kinase domain containing protein 0.0219 0.1746 0.1884
Schistosoma mansoni suppressor of cytokine signaling 0.0052 0.0076 0.0096
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0185 0.1406 0.1502
Trypanosoma brucei protein kinase, putative 0.0078 0.0339 0.1267
Loa Loa (eye worm) AGC/AKT protein kinase 0.0308 0.2644 0.2861
Brugia malayi Protein kinase domain containing protein 0.0192 0.1482 0.1599
Echinococcus granulosus SH2 domain containing protein 7 0.0052 0.0076 0.0076
Entamoeba histolytica protein kinase, putative 0.0104 0.0602 0.1726
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0045 0.0005 0.0005
Echinococcus multilocularis casein kinase I delta 0.0111 0.067 0.0716
Onchocerca volvulus 0.0132 0.0876 0.2568
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0074 0.026
Loa Loa (eye worm) casein kinase 0.0185 0.1411 0.1527
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Echinococcus granulosus tyrosine kinase 0.0097 0.0524 0.0524
Echinococcus multilocularis protein dispatched 1 0.0058 0.014 0.0149
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0157 0.1133 0.4273
Echinococcus granulosus netrin receptor unc 5 0.0083 0.0386 0.0386
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0765 0.0969
Loa Loa (eye worm) protein kinase domain-containing protein 0.0219 0.1746 0.1889
Schistosoma mansoni kinase 0.0296 0.2522 0.3193
Loa Loa (eye worm) hypothetical protein 0.0616 0.5725 0.6194
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0524 0.0567
Giardia lamblia Kinase, NEK 0.0139 0.0953 0.4071
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0508 0.4638 0.4638
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0082 0.038 0.0406
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0045 0.0005 0.0006
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0168 0.124 0.1342
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.019 0.1463 0.1463
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.2333 0.2953
Entamoeba histolytica protein kinase, putative 0.0072 0.0281 0.0797
Schistosoma mansoni cell adhesion molecule 0.005 0.0059 0.0075
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0168 0.124 0.1325
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0052 0.0074 0.0295
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Brugia malayi Tensin 0.0052 0.0076 0.0077
Echinococcus granulosus cGMP dependent protein kinase 1 0.0138 0.0937 0.0937
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0048 0.0038 0.0095
Echinococcus granulosus retinal guanylyl cyclase 2 0.0045 0.0005 0.0005
Echinococcus granulosus nervana 2 0.0127 0.0829 0.0829
Onchocerca volvulus 0.0045 0.0005 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.019 0.1463 0.1852
Echinococcus multilocularis tyrosine kinase 0.0097 0.0524 0.056
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0142 0.0982 0.1062
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0132 0.0876 0.3741
Loa Loa (eye worm) RGC/RGC protein kinase 0.0045 0.0005 0.0005
Echinococcus granulosus tyrosine protein kinase Fyn 0.0185 0.1406 0.1406
Loa Loa (eye worm) hypothetical protein 0.0122 0.0781 0.0845
Echinococcus multilocularis insulin receptor 0.0458 0.4146 0.4429
Echinococcus multilocularis roundabout 2 0.0124 0.0797 0.0852
Onchocerca volvulus 0.0097 0.0524 0.1537
Brugia malayi Immunoglobulin I-set domain containing protein 0.0268 0.2237 0.2416
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0474 0.4307 0.4307
Brugia malayi Cam kinase protein 1 0.0103 0.0589 0.0633
Brugia malayi Temporarily assigned gene name protein 59 0.0133 0.0884 0.0951
Loa Loa (eye worm) CAMK protein kinase 0.0069 0.0245 0.0265
Schistosoma mansoni hypothetical protein 0.0205 0.1605 0.2032
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0148 0.1041 0.1041
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0245 0.031
Giardia lamblia Kinase, CMGC MAPK 0.0086 0.0413 0.1755
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0045 0.0005 0.0005
Onchocerca volvulus 0.0078 0.0336 0.0984
Loa Loa (eye worm) hypothetical protein 0.0051 0.0068 0.0073
Loa Loa (eye worm) TK protein kinase 0.0268 0.2237 0.2421
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0083 0.0385 0.3284
Giardia lamblia Kinase, CAMK CAMKL 0.0091 0.0472 0.2005
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Onchocerca volvulus 0.0097 0.0524 0.1537
Schistosoma mansoni hypothetical protein 0.0052 0.0076 0.0096
Echinococcus multilocularis protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0408 0.3646 0.3944
Giardia lamblia Kinase, CAMK CAMKL 0.0091 0.0472 0.2005
Echinococcus granulosus Vam6:Vps39 protein 0.0115 0.0706 0.0706
Echinococcus multilocularis kinase suppressor of Ras 1 0.0045 0.0005 0.0005
Giardia lamblia Kinase, AGC PKA 0.0116 0.0715 0.3049
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0045 0.0005 0.0005
Trypanosoma cruzi casein kinase II, putative 0.0102 0.0582 0.2479
Onchocerca volvulus 0.0045 0.0005 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.0132 0.0876 0.2515
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0116 0.0715 0.0764
Echinococcus granulosus expressed conserved protein 0.0052 0.0076 0.0076
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0138 0.0937 0.1001
Entamoeba histolytica protein kinase, putative 0.0083 0.039 0.1113
Echinococcus granulosus tyrosine protein kinase csk 0.0045 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0193 0.149 0.5627
Echinococcus granulosus raf serine:threonine protein kinase 0.0088 0.0435 0.0435
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0103 0.0589 0.0638
Schistosoma mansoni tyrosine kinase 0.0373 0.3289 0.4164
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0095 0.0506 0.0541
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.046 0.4167 0.4508
Echinococcus granulosus rho-associated protein kinase 1 0.0334 0.2897 0.2897
Loa Loa (eye worm) TK/ALK protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0061 0.0168 0.0182
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0939 0.1189
Schistosoma mansoni hypothetical protein 0.0115 0.0706 0.0894
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0472 0.0597
Echinococcus multilocularis aurora kinase A 0.0149 0.1049 0.112
Brugia malayi RhoGAP domain containing protein 0.0095 0.0506 0.0543
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0052 0.0076 0.0223
Giardia lamblia Kinase, NEK 0.0045 0.0006 0.0006
Schistosoma mansoni tyrosine kinase 0.0124 0.0803 0.1016
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0193 0.149 0.1612
Plasmodium falciparum protein kinase, putative 0.0078 0.0339 0.2886
Echinococcus multilocularis NCK adaptor protein 0.0082 0.0375 0.0401
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.016 0.1163 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0124 0.0803 0.0863
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2644 1
Loa Loa (eye worm) AUR protein kinase 0.0149 0.1049 0.1135
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0277 0.2333 0.2333
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0445 0.4016 0.4016
Echinococcus granulosus mitogen activated protein kinase 14 0.0163 0.1189 0.1189
Toxoplasma gondii aurora kinase 0.0149 0.1049 0.4098
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2644 1
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0142 0.0982 0.3701
Loa Loa (eye worm) hypothetical protein 0.0143 0.0985 0.1065
Schistosoma mansoni tyrosine kinase 0.0367 0.3228 0.4086
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0223 0.1791 0.1933
Brugia malayi C1-like domain containing protein 0.0223 0.1791 0.1933
Echinococcus multilocularis tyrosine protein kinase csk 0.0045 0.0005 0.0005
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.005 0.0059 0.0075
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0386 0.0412
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0228 0.1838 0.1989
Echinococcus granulosus c src tyrosine kinase 0.0124 0.0803 0.0803
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Onchocerca volvulus 0.0045 0.0005 0.0015
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0069 0.0245 0.0265
Echinococcus multilocularis Glutaredoxin protein 5 0.0127 0.0829 0.0886
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Loa Loa (eye worm) hypothetical protein 0.0068 0.0238 0.0258
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0062
Brugia malayi Variant SH3 domain containing protein 0.0095 0.0506 0.0543
Brugia malayi p70 ribosomal S6 kinase beta 0.0299 0.2552 0.2757
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0582 0.2186
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0052 0.0076 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Schistosoma mansoni tyrosine kinase 0.0079 0.0347 0.0439
Echinococcus granulosus NCK adaptor protein 0.008 0.0354 0.0354
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0005 0.000000084018
Echinococcus multilocularis transfer RNA-Thr 0.0045 0.0005 0.0005
Echinococcus granulosus natriuretic peptide receptor 1 0.0045 0.0005 0.0005
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0064 0.0193 0.0714
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0249 0.2045 0.2184
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0159 0.0167
Echinococcus granulosus aurora kinase A 0.0149 0.1049 0.1049
Echinococcus multilocularis activin receptor type 0.0078 0.0339 0.0362
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0102 0.0582 0.063
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0362 0.3179 0.3179
Brugia malayi Protein kinase domain containing protein 0.0616 0.5725 0.6192
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0103 0.0589 0.2295
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0149 0.1049 0.112
Echinococcus multilocularis dual specificity protein kinase clk2 0.0157 0.1133 0.121
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0091 0.0472 0.051
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0111 0.067 0.0725
Echinococcus multilocularis activated cdc42 kinase 1 0.0045 0.0005 0.0005
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0056 0.0114 0.0123
Loa Loa (eye worm) AUR protein kinase 0.0149 0.1049 0.1135
Entamoeba histolytica protein kinase, putative 0.0149 0.1049 0.3015
Echinococcus multilocularis serine:threonine protein kinase 38 0.0172 0.128 0.1367
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0052 0.0076 0.0076
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Schistosoma mansoni nephrin 0.005 0.0059 0.0075
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0149 0.1049 0.901
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0116 0.0715 0.269
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0103 0.0589 0.5045
Echinococcus granulosus casein kinase I alpha 0.0111 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0085 0.041 0.1171
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0095 0.0506 0.0506
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0148 0.1042 0.1113
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.1774 0.2246
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0085 0.0407 0.1727
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.0589 0.063
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0122 0.0774 0.0774
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0354 0.3106 0.336
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.0456 0.0488
Entamoeba histolytica casein kinase, putative 0.0111 0.067 0.192
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.197 0.2493
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Entamoeba histolytica serine/threonine protein kinase, putative 0.0091 0.0472 0.1348
Loa Loa (eye worm) CDC7 protein kinase 0.0092 0.0475 0.0514
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0088 0.0437 0.0467
Loa Loa (eye worm) hypothetical protein 0.0091 0.0472 0.051
Entamoeba histolytica protein kinase, putative 0.0149 0.1049 0.3015
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0089 0.0444 0.0444
Loa Loa (eye worm) RGC/RGC protein kinase 0.0045 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Loa Loa (eye worm) TK protein kinase 0.0357 0.3126 0.3382
Brugia malayi Protein kinase domain containing protein 0.0362 0.3179 0.3436
Echinococcus multilocularis serine:threonine protein kinase 0.0117 0.0726 0.0776
Echinococcus multilocularis raf serine:threonine protein kinase 0.0088 0.0435 0.0465
Loa Loa (eye worm) hypothetical protein 0.0092 0.0475 0.0514
Schistosoma mansoni signal transduction protein lnk-related 0.0052 0.0076 0.0096
Echinococcus multilocularis nervana 2 0.0127 0.0829 0.0886
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Giardia lamblia Kinase, CMGC GSK 0.0132 0.0876 0.3741
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.1049 0.1327
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0045 0.0008 0.0009
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Trypanosoma cruzi p21-activated kinase 3, putative 0.0056 0.0114 0.0469
Entamoeba histolytica ankyrin repeat protein 0.0045 0.0005 0.000000064046
Loa Loa (eye worm) hypothetical protein 0.0143 0.0985 0.1065
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.2333 0.882
Onchocerca volvulus 0.0143 0.0985 0.2887
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0086 0.0413 0.1755
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0116 0.0715 0.0715
Echinococcus granulosus death domain containing protein 0.0068 0.0237 0.0237
Schistosoma mansoni cell adhesion molecule 0.005 0.0059 0.0075
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0085 0.0407 0.044
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0405 0.3608 0.3608
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0362 0.3179 0.344
Schistosoma mansoni suppressor of cytokine signaling 0.0052 0.0076 0.0096
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0222 0.1784 0.193
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0005 0.0006
Brugia malayi Protein kinase domain containing protein 0.0168 0.124 0.1337
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0052 0.0076 0.0223
Brugia malayi Protein kinase domain containing protein 0.0193 0.149 0.1608
Loa Loa (eye worm) hypothetical protein 0.0124 0.0798 0.0864
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0083 0.039 0.0422
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0072 0.0281 0.0281
Echinococcus granulosus casein kinase I alpha 0.0111 0.067 0.067
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0045 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.197 0.2493
Loa Loa (eye worm) sex muscle abnormal protein 5 0.008 0.0354 0.0383
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0435 0.0551
Brugia malayi Protein kinase domain containing protein 0.046 0.4167 0.4505
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.1258 0.1258
Loa Loa (eye worm) AGC/PKG protein kinase 0.0138 0.0937 0.1013
Echinococcus multilocularis calcium dependent protein kinase 0.007 0.0255 0.0273
Brugia malayi Variant SH3 domain containing protein 0.0062 0.0181 0.019
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0339 0.1436
Leishmania major serine/threonine-protein kinase, putative 0.0052 0.0074 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.1723 0.2181
Echinococcus granulosus tyrosine protein kinase Blk 0.0157 0.1128 0.1128
Echinococcus granulosus tyrosine protein kinase ABL1 0.0097 0.0524 0.0524
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0045 0.0005 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0472 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.1617 0.2047
Entamoeba histolytica protein kinase, putative 0.0308 0.2644 0.7623
Entamoeba histolytica protein kinase, putative 0.0103 0.0589 0.1688
Brugia malayi Sex muscle abnormal protein 5 0.008 0.0354 0.0378
Echinococcus multilocularis tyrosine kinase 0.0045 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0281 0.0355
Trichomonas vaginalis STE family protein kinase 0.0066 0.0214 0.0791
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0221 0.1774 0.1895
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0185 0.1406 0.1502
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0223 0.1791 0.1937
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0078 0.0339 0.1312
Onchocerca volvulus 0.0063 0.019 0.0558
Onchocerca volvulus 0.0334 0.2897 0.8495
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0116 0.0715 0.3049
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0408 0.3646 0.3894
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0005 0.0005
Echinococcus granulosus SHC transforming protein 3 0.0052 0.0076 0.0076
Echinococcus multilocularis natriuretic peptide receptor 1 0.0045 0.0005 0.0005
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0052 0.0074 0.0295
Schistosoma mansoni nck2/grb4 0.008 0.0354 0.0449
Echinococcus granulosus serine threonine protein kinase nrc 0.016 0.1163 0.1163
Echinococcus multilocularis Immunoglobulin 0.0074 0.0295 0.0315
Echinococcus multilocularis protein kinase shaggy 0.0132 0.0876 0.0936
Schistosoma mansoni protein tyrosine kinase 0.0045 0.0005 0.0006
Echinococcus granulosus myotubularin protein 13 0.0052 0.0079 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0413 0.1548
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0068 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.0233
Brugia malayi Variant SH3 domain containing protein 0.008 0.0354 0.0378
Echinococcus multilocularis 0.0178 0.1343 0.1435
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0241 0.197 0.197
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0052 0.0076 0.0076
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0103 0.0589 0.0589
Brugia malayi hypothetical protein 0.0052 0.0076 0.0077
Schistosoma mansoni protein kinase C mu 0.0223 0.1791 0.2267
Trichomonas vaginalis AGC family protein kinase 0.0149 0.1049 0.3955
Echinococcus multilocularis protein tyrosine kinase 0.0565 0.5212 0.5568
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0125 0.081 0.0876
Schistosoma mansoni protein kinase 0.0045 0.0005 0.0006
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0198 0.1536 0.1661
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0208 0.1637 0.1748
Toxoplasma gondii AGC kinase 0.0116 0.0715 0.2787
Schistosoma mansoni protein kinase 0.0078 0.0339 0.0429
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Schistosoma mansoni vam6/vps39 related 0.0115 0.0706 0.0894
Echinococcus granulosus fibroblast growth factor receptor 4 0.0249 0.2045 0.2045
Schistosoma mansoni growth factor receptor-bound protein 0.0082 0.0375 0.0475
Entamoeba histolytica p21-activated kinase 0.0097 0.0529 0.1513
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0159 0.0167
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0185 0.1406 0.1502
Echinococcus multilocularis 0.0052 0.0076 0.0081
Brugia malayi Death domain containing protein 0.0068 0.0237 0.0251
Brugia malayi serine/threonine-protein kinase plk-2 0.0277 0.2333 0.252
Trypanosoma cruzi cdc2-related kinase 3 0.0122 0.0774 0.3305
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0405 0.3608 0.3854
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0122 0.0774 0.0838
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0238 0.1939 0.1939
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0982 0.1243
Trichomonas vaginalis AGC family protein kinase 0.0083 0.039 0.146
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0221 0.1774 0.1774
Brugia malayi casein kinase I 0.0111 0.067 0.072
Loa Loa (eye worm) hypothetical protein 0.0052 0.0079 0.0085
Schistosoma mansoni serine/threonine-protein kinase 0.017 0.1255 0.1589
Trichomonas vaginalis TKL family protein kinase 0.0045 0.0005 0.000000084018
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0072 0.0281 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.2145 0.2715
Giardia lamblia Protein 21.1 0.0045 0.0005 0.000000095259
Trichomonas vaginalis CMGC family protein kinase 0.0122 0.0774 0.2915
Echinococcus multilocularis expressed conserved protein 0.0112 0.0675 0.0721
Echinococcus multilocularis SH2 domain containing protein 7 0.0052 0.0076 0.0081
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0097 0.0524 0.056
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0362 0.3179 0.344
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0157 0.1133 0.4273
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0122 0.0774 0.0838
Giardia lamblia Kinase, AGC AKT 0.012 0.0756 0.3228
Brugia malayi protein unc-22 0.0069 0.0245 0.0259
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2644 1
Giardia lamblia Kinase, NEK 0.0139 0.0953 0.4071
Trichomonas vaginalis STE family protein kinase 0.0139 0.0953 0.3591
Echinococcus granulosus Ankyrin 0.0068 0.0238 0.0238
Echinococcus multilocularis expressed protein 0.0085 0.0407 0.0435
Loa Loa (eye worm) hypothetical protein 0.0074 0.0295 0.0319
Echinococcus granulosus contactin 0.005 0.0059 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0582 0.2186
Schistosoma mansoni tyrosine kinase 0.0124 0.0803 0.1016
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0362 0.3179 0.3396
Trypanosoma brucei casein kinase I, isoform 2 0.0111 0.067 0.2519
Loa Loa (eye worm) hypothetical protein 0.0062 0.0182 0.0197
Echinococcus granulosus geminin 0.0205 0.1605 0.1605
Echinococcus multilocularis serine:threonine protein kinase N2 0.0172 0.128 0.1367
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0059 0.0059
Brugia malayi P38 map kinase family protein 2 0.0163 0.1189 0.1282
Loa Loa (eye worm) hypothetical protein 0.0115 0.0706 0.0764
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0374 0.3296 0.3521
Brugia malayi SH2 domain containing protein 0.0052 0.0076 0.0077
Echinococcus granulosus hypothetical protein 0.0052 0.0076 0.0076
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0116 0.0715 0.0715
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Echinococcus multilocularis casein kinase ii subunit alpha 0.0102 0.0582 0.0622
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.0277 0.2333 1
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0125 0.081 0.3457
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Onchocerca volvulus 0.0111 0.067 0.1964
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0068 0.0237
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0271 0.2271 0.2426
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0085 0.0407 0.1578
Giardia lamblia Kinase, STE STE20 0.0088 0.0437 0.1855
Echinococcus granulosus receptor type guanylyl cyclase 0.0045 0.0005 0.0005
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0086 0.0413 0.1755
Echinococcus granulosus tyrosine protein kinase pr2 0.0045 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0221 0.1774 0.1895
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0045 0.0005 0.0006
Echinococcus granulosus protein kinase 0.0045 0.0005 0.0005
Onchocerca volvulus Tyrosine kinase homolog 0.0385 0.341 1
Echinococcus granulosus dual specificity 0.0125 0.081 0.081
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0148 0.1041 0.1112
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0045 0.0005 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0142 0.0982 0.3701
Schistosoma mansoni tyrosine kinase 0.0625 0.5818 0.7365
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0052 0.0076 0.0081
Entamoeba histolytica hypothetical protein 0.0125 0.081 0.2324
Brugia malayi Protein kinase domain containing protein 0.0172 0.128 0.138
Schistosoma mansoni tyrosine kinase 0.0077 0.0328 0.0415
Echinococcus granulosus integrin linked protein kinase 0.0045 0.0005 0.0005
Echinococcus granulosus insulin receptor 0.0458 0.4146 0.4146
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0221 0.1774 0.1774
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0399 0.3547 0.3789
Echinococcus granulosus tyrosine protein kinase shark 0.0316 0.2722 0.2722
Schistosoma mansoni serine/threonine protein kinase 0.0257 0.2131 0.2697
Loa Loa (eye worm) STAT protein 0.0052 0.0076 0.0082
Echinococcus granulosus epidermal growth factor receptor 0.0411 0.3676 0.3676
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0362 0.3179 0.9323
Plasmodium vivax protein kinase, putative 0.006 0.016 0.134
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Echinococcus granulosus casein kinase i 0.0111 0.067 0.067
Echinococcus multilocularis titin 0.0069 0.0245 0.0261
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0953 0.3591
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0115 0.0706 0.0894
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0087 0.0423 0.1207
Onchocerca volvulus 0.0092 0.0475 0.1394
Echinococcus multilocularis protein KINase family member (kin 25) 0.0045 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Brugia malayi hypothetical protein 0.0228 0.1838 0.1984
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.2333 0.882
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0159 0.0173
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0116 0.0715 0.0764
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0208 0.1637 0.1637
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0475 0.1783
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0524 0.0567
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.0589 0.063
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0142 0.0982 0.3835
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0967 0.9243 1
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0472 0.0597
Onchocerca volvulus 0.0092 0.0475 0.1394
Schistosoma mansoni titin 0.0069 0.0245 0.031
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0149 0.1049 0.3015
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2644 1
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0172 0.128 0.1367
Echinococcus granulosus suppressor of cytokine signaling 6 0.0052 0.0076 0.0076
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0052 0.0076 0.0082
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0005 0.0005
Echinococcus multilocularis SH2 motif 0.0052 0.0076 0.0081
Schistosoma mansoni hypothetical protein 0.0068 0.0237 0.0299
Entamoeba histolytica protein kinase domain containing protein 0.0132 0.0876 0.2515
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0524 0.0567
Loa Loa (eye worm) hypothetical protein 0.0097 0.0524 0.0567
Schistosoma mansoni protein kinase 0.0238 0.1939 0.2454
Trypanosoma brucei cdc2-related kinase 1 0.0122 0.0774 0.2915
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0129 0.0848 0.3623
Schistosoma mansoni tyrosine kinase 0.0411 0.3676 0.4654
Loa Loa (eye worm) TK protein kinase 0.0045 0.0005 0.0005
Onchocerca volvulus 0.0321 0.2769 0.8121
Echinococcus multilocularis mitogen activated protein kinase 14 0.0163 0.1189 0.127
Echinococcus granulosus casein kinase I alpha 0.0111 0.067 0.067
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0299 0.2552 0.2761
Echinococcus granulosus c-Jun N-terminal kinases 0.0271 0.2271 0.2271
Echinococcus granulosus Glutaredoxin protein 5 0.0127 0.0829 0.0829
Schistosoma mansoni protein kinase 0.0045 0.0006 0.0008
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0111 0.067 0.0725
Trichomonas vaginalis CMGC family protein kinase 0.0132 0.0876 0.3299
Echinococcus multilocularis serine:threonine protein kinase 3 0.0263 0.2194 0.2344
Brugia malayi ephrin receptor 1 precursor 0.0076 0.0315 0.0336
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0116 0.0715 0.269
Leishmania major protein kinase A catalytic subunit 0.0116 0.0715 0.3049
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0103 0.0589 0.0589
Trichomonas vaginalis STE family protein kinase 0.0088 0.0437 0.1636
Schistosoma mansoni nephrin 0.0109 0.0648 0.0821
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0852 0.321
Echinococcus granulosus protein kinase shaggy 0.0132 0.0876 0.0876
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.1258 0.1344
Trichomonas vaginalis CAMK family protein kinase 0.0118 0.0736 0.277
Trypanosoma cruzi rac serine-threonine kinase, putative 0.016 0.1163 0.4977
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0117 0.0726 0.0785
Trypanosoma brucei rac serine-threonine kinase, putative 0.0308 0.2644 1
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0157 0.1128 0.122
Echinococcus multilocularis cyclin dependent kinase 5 0.0122 0.0774 0.0827
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0052 0.0076 0.0096
Echinococcus multilocularis tyrosine protein kinase csk 0.0045 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0097 0.0524 0.0562
Leishmania major protein kinase, putative 0.0157 0.1133 0.4845
Giardia lamblia Kinase, NEK 0.0139 0.0953 0.4071
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0524 0.0567
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0088 0.044 0.0476
Plasmodium vivax glycogen synthase kinase 3, putative 0.0132 0.0876 0.7517
Echinococcus granulosus dual specificity 0.0142 0.0982 0.0982
Brugia malayi Protein kinase domain containing protein 0.0571 0.5274 0.5704
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0774 0.098
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0017 0.0045
Echinococcus granulosus activated cdc42 kinase 1 0.0045 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase 0.0117 0.0726 0.0776
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0228 0.1838 0.1838
Onchocerca volvulus 0.0115 0.0706 0.2071
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0074 0.0295 0.0315
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0116 0.0715 0.3049
Trichomonas vaginalis CMGC family protein kinase 0.0122 0.0774 0.2915
Loa Loa (eye worm) RGC/RGC protein kinase 0.0045 0.0005 0.0005
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0122 0.0774 0.3305
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0132 0.0876 0.3419
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0084 0.0394 0.0426
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0045 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0524 0.0567
Echinococcus multilocularis casein kinase I delta 0.0111 0.067 0.0716
Brugia malayi Protein kinase domain containing protein 0.0157 0.1133 0.1221
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0088 0.0437 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Schistosoma mansoni tyrosine kinase 0.0249 0.2045 0.2588
Brugia malayi Protein kinase domain containing protein 0.0206 0.1617 0.1745
Plasmodium falciparum NIMA related kinase 1 0.0139 0.0953 0.8181
Entamoeba histolytica protein kinase, putative 0.0066 0.0214 0.0603
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0125 0.081 0.3457
Entamoeba histolytica protein kinase, putative 0.0125 0.081 0.2324
Echinococcus granulosus expressed protein 0.0085 0.0407 0.0407
Plasmodium falciparum calcium-dependent protein kinase 1 0.0103 0.0589 0.5045
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0715 0.0905
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0052 0.0076 0.0081
Plasmodium falciparum protein kinase 5 0.0122 0.0774 0.6641
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0047 0.0026 0.0026
Echinococcus multilocularis integrin linked protein kinase 0.0045 0.0005 0.0005
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0088 0.0437 0.0467
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0086 0.0413 0.1755
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0271 0.2271 0.2457
Echinococcus granulosus CDC7 cell division cycle 7 0.0092 0.0475 0.0475
Schistosoma mansoni tensin 0.0052 0.0076 0.0096
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0095 0.0506 0.0641
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0103 0.0589 0.5045
Echinococcus multilocularis myotubularin protein 13 0.0052 0.0079 0.0084
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0078 0.0339 0.1267
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0087 0.0423 0.1795
Echinococcus granulosus tyrosine kinase 0.0045 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0088 0.0437 0.0553
Trypanosoma cruzi casein kinase, putative 0.0111 0.067 0.2856
Loa Loa (eye worm) hypothetical protein 0.0084 0.0395 0.0427
Entamoeba histolytica PH domain containing protein kinase, putative 0.017 0.1255 0.3612
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0185 0.1406 0.1406
Onchocerca volvulus 0.019 0.1457 0.4271
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0078 0.0336 0.142
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0937 0.1186
Echinococcus multilocularis tyrosine protein kinase Srms 0.0157 0.1128 0.1204
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Entamoeba histolytica casein kinase 1, putative 0.0111 0.067 0.192
Brugia malayi Protein kinase domain 0.0088 0.0437 0.0467
Trypanosoma cruzi cdc2-related kinase 1 0.0122 0.0774 0.3305
Entamoeba histolytica protein kinase, putative 0.0075 0.0306 0.0869
Loa Loa (eye worm) TK/FER protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0263 0.2194 0.2374
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0017 0.0045
Brugia malayi Stress-activated protein kinase jnk-1 0.0271 0.2271 0.2453
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0228 0.1838 0.1964
Echinococcus granulosus tyrosine protein kinase Src42A 0.0185 0.1406 0.1406
Schistosoma mansoni adapter molecule crk 0.008 0.0354 0.0449
Giardia lamblia Kinase, CMGC DYRK 0.0142 0.0982 0.4196
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0132 0.0876 0.0947
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0155 0.1104 0.1194
Loa Loa (eye worm) hypothetical protein 0.0148 0.1034 0.1118
Echinococcus granulosus serine:threonine protein kinase N2 0.0133 0.0891 0.0891
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Onchocerca volvulus 0.0052 0.0076 0.0223
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0103 0.0589 0.2295
Trichomonas vaginalis TKL family protein kinase 0.0046 0.0017 0.0045
Trypanosoma brucei polo-like protein kinase 0.0277 0.2333 0.882
Echinococcus granulosus cGMP dependent protein kinase 0.0138 0.0937 0.0937
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.014 0.0146
Brugia malayi Casein kinase II, alpha chain 0.0102 0.0582 0.0625
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0045 0.0005 0.0005
Echinococcus granulosus activated cdc42 kinase 1 0.0045 0.0005 0.0005
Entamoeba histolytica serine/threonine protein kinase, putative 0.0277 0.2333 0.6723
Echinococcus granulosus serine:threonine protein kinase N2 0.0305 0.2614 0.2614
Schistosoma mansoni protein kinase 0.0445 0.4016 0.5084
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0118 0.0736 0.0736
Schistosoma mansoni protein kinase 0.0198 0.1536 0.1944
Echinococcus multilocularis tyrosine protein kinase 0.0291 0.2472 0.264
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0139 0.0953 0.8181
Schistosoma mansoni serine/threonine protein kinase 0.0334 0.2897 0.3667
Toxoplasma gondii NEK kinase 0.0052 0.0074 0.027
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0095 0.0506 0.0641
Leishmania major protein kinase, putative 0.0157 0.1133 0.4845
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0091 0.0472 0.2005
Loa Loa (eye worm) SH2 domain-containing protein 0.0052 0.0076 0.0082
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0091 0.0472 0.2005
Echinococcus multilocularis contactin neuroglian septate junction protein 0.005 0.0059 0.0064
Entamoeba histolytica protein kinase 2, putative 0.016 0.1163 0.3346
Giardia lamblia Kinase, CMGC CLK 0.0157 0.1133 0.4845
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.009 0.0456 0.0493
Onchocerca volvulus 0.0147 0.1026 0.3009
Trichomonas vaginalis AGC family protein kinase 0.0083 0.039 0.146
Schistosoma mansoni protein kinase 0.0045 0.0005 0.0006
Brugia malayi Fes/CIP4 homology domain containing protein 0.0106 0.0616 0.0661
Trichomonas vaginalis STE family protein kinase 0.0088 0.0437 0.1636
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0086 0.0413 0.1548
Brugia malayi Protein kinase domain containing protein 0.0045 0.0005 0.000000024002
Trypanosoma cruzi casein kinase, putative 0.0111 0.067 0.2856
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.016 0.1163 0.1163
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0116 0.0715 0.269
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.9361 1
Giardia lamblia Kinase, CMGC SRPK 0.0085 0.0407 0.1727
Echinococcus multilocularis heat shock protein 70 0.0045 0.0005 0.0005
Schistosoma mansoni SH2A 0.0052 0.0076 0.0096
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0216 0.1723 0.1864
Echinococcus granulosus mitogen activated protein kinase 0.0086 0.0413 0.0413
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.019 0.1463 0.1563
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0589 0.2215
Giardia lamblia Kinase, PLK 0.0277 0.2333 1
Schistosoma mansoni tyrosine kinase 0.0045 0.0005 0.0006
Brugia malayi Protein kinase domain containing protein 0.0198 0.1536 0.1657
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0149 0.1049 0.3955
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0125 0.081 0.3457
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0606 0.0767
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0116 0.0715 0.0768
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0111 0.067 0.2856
Echinococcus granulosus SH2 motif 0.0052 0.0076 0.0076
Echinococcus granulosus tyrosine protein kinase csk 0.0045 0.0005 0.0005
Brugia malayi SH2 domain containing protein 0.0052 0.0076 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.2333 0.882
Echinococcus granulosus protein kinase C gamma type 0.0214 0.1701 0.1701
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0083 0.0385 0.1494
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0475 0.1783
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.039 0.0494
Onchocerca volvulus 0.0052 0.0076 0.0223
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0101 0.0365
Loa Loa (eye worm) TK/CSK protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0474 0.4304 0.4656
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0172 0.128 0.1367
Echinococcus granulosus nuclear factor of activated T cells 5 0.0374 0.3296 0.3296
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0157 0.1133 0.4845
Schistosoma mansoni protein kinase 0.0045 0.0005 0.0006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0185 0.1406 0.1502
Loa Loa (eye worm) variant SH3 domain-containing protein 0.008 0.0354 0.0383
Brugia malayi Protein kinase domain containing protein 0.0097 0.0524 0.0562
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.1133 0.1434
Echinococcus granulosus tyrosine protein kinase Src64B 0.0185 0.1406 0.1406
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0774 0.098
Echinococcus multilocularis cyclin dependent kinase 1 0.0122 0.0774 0.0827
Plasmodium falciparum serine/threonine protein kinase, putative 0.0149 0.1049 0.901
Loa Loa (eye worm) hypothetical protein 0.0052 0.0076 0.0082
Echinococcus multilocularis N chimaerin 0.0095 0.0506 0.0541
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0086 0.0413 0.0447
Brugia malayi Protein kinase domain containing protein 0.0308 0.2644 0.2857
Echinococcus multilocularis ephrin type A receptor 4 A 0.0111 0.0664 0.0709
Schistosoma mansoni tyrosine kinase 0.0367 0.3228 0.4086
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0445 0.4016 0.429
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0114 0.0144
Schistosoma mansoni protein kinase 0.0376 0.3325 0.4209
Plasmodium falciparum calcium-dependent protein kinase 5 0.0103 0.0589 0.5045
Schistosoma mansoni neuroglian 0.005 0.0059 0.0075
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0068 0.0237 0.0253
Brugia malayi SRC-1 0.0185 0.1406 0.1517
Brugia malayi Fibronectin type III domain containing protein 0.009 0.0456 0.0488
Echinococcus multilocularis serine threonine protein kinase 0.0214 0.1701 0.1817
Loa Loa (eye worm) RGC/RGC protein kinase 0.0045 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.008 0.0354 0.0383
Echinococcus granulosus serine:threonine protein kinase 3 0.0263 0.2194 0.2194
Schistosoma mansoni tyrosine kinase 0.0316 0.2722 0.3446
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0472 0.1769
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0074 0.0295 0.0373
Trichomonas vaginalis AGC family protein kinase 0.0308 0.2644 1
Brugia malayi Protein kinase domain containing protein 0.0616 0.5725 0.6192
Schistosoma mansoni tyrosine kinase 0.0458 0.4146 0.5248
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0132 0.0876 0.0876
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0277 0.2333 1
Echinococcus granulosus tyrosine protein kinase HCK 0.0105 0.0608 0.0608
Loa Loa (eye worm) TK protein kinase 0.0291 0.2472 0.2674
Loa Loa (eye worm) hypothetical protein 0.0143 0.0985 0.1065
Brugia malayi protein kinase C II. 0.0216 0.1723 0.186
Loa Loa (eye worm) hypothetical protein 0.0105 0.0605 0.0655
Echinococcus granulosus tyrosine protein kinase Fyn 0.0185 0.1406 0.1406
Echinococcus granulosus activin receptor type 0.0078 0.0339 0.0339
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0091 0.0472 0.1769
Schistosoma mansoni protein kinase 0.0111 0.067 0.0848
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.005 0.0059 0.0064
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.016 0.1163 1
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0087 0.0423 0.1207
Echinococcus multilocularis growth factor receptor bound protein 2 0.008 0.0354 0.0379
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0715 0.0905
Schistosoma mansoni tyrosine kinase 0.0264 0.2202 0.2787
Brugia malayi Furin-like cysteine rich region family protein 0.0625 0.5818 0.6293
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0148 0.1042 0.1042
Trypanosoma cruzi casein kinase, putative 0.0111 0.067 0.2856
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0208 0.1637 0.1766
Echinococcus granulosus SH2 domain containing adapter protein F 0.0052 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.0205 0.1605 0.2032
Plasmodium falciparum protein serine/threonine kinase-1 0.0157 0.1133 0.9735
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0376 0.3325 0.3325
Schistosoma mansoni hypothetical protein 0.0052 0.0076 0.0096
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0127 0.0829 0.0829
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0103 0.0589 0.2295
Onchocerca volvulus 0.0045 0.0005 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0103 0.037
Toxoplasma gondii NEK kinase 0.0052 0.0074 0.027
Echinococcus multilocularis cyclin dependent kinase 0.0122 0.0774 0.0827
Echinococcus multilocularis dual specificity 0.0142 0.0982 0.1049
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0115 0.0706 0.3014
Loa Loa (eye worm) hypothetical protein 0.0147 0.1026 0.111
Giardia lamblia Kinase, CMGC CDK 0.0122 0.0774 0.3305
Loa Loa (eye worm) hypothetical protein 0.0115 0.0706 0.0764
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0474 0.4307 0.4601
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0362 0.3179 0.3436
Echinococcus granulosus dual specificity protein kinase clk2 0.0157 0.1133 0.1133
Schistosoma mansoni serine/threonine kinase 0.0172 0.128 0.162
Entamoeba histolytica protein kinase, putative 0.0045 0.0005 0.000000064046
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0715 0.0905
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.019 0.1463 0.1583
Echinococcus granulosus cGMP dependent protein kinase 1 0.0138 0.0937 0.0937
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0122 0.0774 0.302
Entamoeba histolytica protein kinase, putative 0.0085 0.0407 0.1161
Loa Loa (eye worm) hypothetical protein 0.0045 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0055 0.0103 0.0111
Entamoeba histolytica protein kinase, putative 0.0085 0.0407 0.1161
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0259 0.2145 0.2145
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0249 0.2045 0.2045
Trypanosoma brucei aurora B kinase 0.0149 0.1049 0.3955
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0245 0.0259
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0206 0.1617 0.1617
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0091 0.0472 0.0504
Entamoeba histolytica protein kinase, putative 0.0125 0.081 0.2324
Echinococcus granulosus NDR protein kinase 0.0172 0.128 0.128
Echinococcus multilocularis roundabout 2 0.005 0.0059 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0193 0.0714
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0157 0.1128 0.1204
Onchocerca volvulus Netrin receptor homolog 0.0087 0.0429 0.1258
Echinococcus multilocularis neuroglian 0.005 0.0059 0.0064
Brugia malayi SH2 domain containing protein 0.0052 0.0076 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.128 0.162
Echinococcus multilocularis serine:threonine protein kinase N2 0.0305 0.2614 0.2792
Loa Loa (eye worm) TK/Met protein kinase 0.0045 0.0005 0.0005
Giardia lamblia Kinase, CMGC GSK 0.0132 0.0876 0.3741
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0083 0.039 0.0417
Schistosoma mansoni hypothetical protein 0.0045 0.0005 0.0006
Echinococcus multilocularis protein patched 0.0051 0.0068 0.0072
Echinococcus granulosus cyclin dependent kinase 0.0122 0.0774 0.0774
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.2271 0.2874
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0052 0.0076 0.0082
Schistosoma mansoni protein kinase 0.0045 0.0005 0.0006
Echinococcus multilocularis dual specificity 0.0125 0.081 0.0865
Loa Loa (eye worm) TK/INSR protein kinase 0.0458 0.4146 0.4485
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0102 0.0582 0.498
Echinococcus multilocularis myosin iiia 0.0087 0.0423 0.0452
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0132 0.0876 0.1108
Brugia malayi CHE-14 protein 0.0051 0.0068 0.0068
Brugia malayi putative serine/threonine kinase SADA gamma 0.0091 0.0472 0.0505
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0206 0.1617 0.175

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 1.19 um PUBCHEM_BIOASSAY: Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response. (Class of assay: confirmatory) [Related pubchem assays: 1239 ] ChEMBL. No reference
Potency (functional) 0.4109 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 0.7079 um PUBCHEM_BIOASSAY: qHTS Assay for Rab9 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.8492 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 0.8913 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.0323 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 1.5849 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.8356 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 1.8526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.3225 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 12.9953 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 16.3601 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 17.7828 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 84.9214 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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