Detailed information for compound 1433163

Basic information

Technical information
  • TDR Targets ID: 1433163
  • Name: 2-[[5,6-di(furan-2-yl)-1,2,4-triazin-3-yl]sul fanyl]-N-(2,6-dimethylphenyl)acetamide
  • MW: 406.458 | Formula: C21H18N4O3S
  • H donors: 1 H acceptors: 4 LogP: 3.2 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1c(C)cccc1C)CSc1nnc(c(n1)c1ccco1)c1ccco1
  • InChi: 1S/C21H18N4O3S/c1-13-6-3-7-14(2)18(13)22-17(26)12-29-21-23-19(15-8-4-10-27-15)20(24-25-21)16-9-5-11-28-16/h3-11H,12H2,1-2H3,(H,22,26)
  • InChiKey: AJZYCLUWDCVNLC-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 2-[[5,6-bis(2-furyl)-1,2,4-triazin-3-yl]sulfanyl]-N-(2,6-dimethylphenyl)acetamide
  • 2-[[5,6-bis(2-furyl)-1,2,4-triazin-3-yl]thio]-N-(2,6-dimethylphenyl)acetamide
  • 2-[[5,6-di(furan-2-yl)-1,2,4-triazin-3-yl]sulfanyl]-N-(2,6-dimethylphenyl)ethanamide
  • 2-(5,6-Di-furan-2-yl-[1,2,4]triazin-3-ylsulfanyl)-N-(2,6-dimethyl-phenyl)-acetamide
  • MLS000556463
  • SMR000147780
  • BAS 02832765
  • STOCK3S-67696
  • ZINC00882766

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens arachidonate 15-lipoxygenase, type B Starlite/ChEMBL No references
Homo sapiens l(3)mbt-like 1 (Drosophila) Starlite/ChEMBL No references
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Starlite/ChEMBL No references
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)(HIV-1) Human immunodeficiency virus type 1 Tat protein Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens tyrosyl-DNA phosphodiesterase 1 Starlite/ChEMBL No references
Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens RecQ helicase-like Starlite/ChEMBL No references
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Homo sapiens pyruvate kinase, muscle Starlite/ChEMBL No references
Homo sapiens myeloid cell leukemia 1 Starlite/ChEMBL No references
Homo sapiens glucosidase, beta, acid Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), eta Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references
Plasmodium falciparum M17 leucyl aminopeptidase Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens K(lysine) acetyltransferase 2A Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens estrogen receptor 2 (ER beta) Starlite/ChEMBL No references
Homo sapiens glutaminase Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma brucei gambiense tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Loa Loa (eye worm) pyruvate kinase-PB Get druggable targets OG5_126685 All targets in OG5_126685
Neospora caninum Pc21g17280 protein, related Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani cytosolic leucyl aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum peptidyl-prolyl cis-trans isomerase NIMA- interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) glutaminase 2 Get druggable targets OG5_129245 All targets in OG5_129245
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium leprae Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense metallo-peptidase, Clan MF, Family M17, putative Get druggable targets OG5_127293 All targets in OG5_127293
Trypanosoma brucei gambiense cytosolic leucyl aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17, putative Get druggable targets OG5_127293 All targets in OG5_127293
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania donovani pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania braziliensis cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Brugia malayi glutaminase DH11.1 Get druggable targets OG5_129245 All targets in OG5_129245
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania donovani tyrosyl-DNA phosphodiesterase-like protein Get druggable targets OG5_129037 All targets in OG5_129037
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi acetyltransferase, GNAT family protein Get druggable targets OG5_127781 All targets in OG5_127781
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_129037 All targets in OG5_129037
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Lethal(3)malignant brain tumor-like 4 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Leishmania mexicana cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K06062 p300/CBP-associated factor, putative Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Onchocerca volvulus Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus granulosus transcription factor Dp 1 Get druggable targets OG5_129037 All targets in OG5_129037
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Theileria parva peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium yoelii putative leucine aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania donovani peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania mexicana peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum Pyruvate kinase isozyme R, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium berghei histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium berghei pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Cryptosporidium hominis proteinx0005 Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase Get druggable targets OG5_129037 All targets in OG5_129037
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni rotamase Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis leucine aminopeptidase protein Get druggable targets OG5_127293 All targets in OG5_127293
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium parvum tyrosyl-DNA phodphodiesterase 1 (tdp1) Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus multilocularis dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130415 All targets in OG5_130415
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium yoelii histone acetyltransferase GCN5-related Get druggable targets OG5_127781 All targets in OG5_127781
Brugia malayi ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Lethal(3)malignant brain tumor-like 3 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Leishmania braziliensis tyrosyl-DNA phosphodiesterase, putative;with=GeneDB:LinJ33_V3.3210 Get druggable targets OG5_129037 All targets in OG5_129037
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania major tyrosyl-DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Mycobacterium ulcerans leucyl aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi M17 leucyl aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Babesia bovis peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Toxoplasma gondii leucyl aminopeptidase LAP Get druggable targets OG5_127293 All targets in OG5_127293
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Giardia lamblia Histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Cryptosporidium parvum DinB/family X-type DNA polymerase Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Babesia bovis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium vivax M17 leucyl aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana tyrosyl-DNA phosphodiesterase-like protein Get druggable targets OG5_129037 All targets in OG5_129037
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum expressed protein Get druggable targets OG5_129301 All targets in OG5_129301
Mycobacterium ulcerans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium parvum putative leucine aminopeptidase; of possible plant or bacterial origin Get druggable targets OG5_127293 All targets in OG5_127293
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma congolense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma congolense tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium falciparum histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Plasmodium berghei M17 leucyl aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium hominis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma congolense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis bromodomain-containing protein, putative Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Cryptosporidium hominis leucine aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K00142 aminoadipate-semialdehyde dehydrogenase [EC1.2.1.31], putative Get druggable targets OG5_129301 All targets in OG5_129301
Mycobacterium tuberculosis Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus granulosus endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Echinococcus granulosus dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative Get druggable targets OG5_129037 All targets in OG5_129037
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum ko:K09578 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania infantum peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus leucine aminopeptidase protein Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania braziliensis peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128521 All targets in OG5_128521
Chlamydia trachomatis cytosol aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Babesia bovis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma japonicum ko:K00873 pyruvate kinase [EC2.7.1.40], putative Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei pyruvate kinase 1 Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trypanosoma brucei DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K01113 phosphodiesterase/alkaline phosphatase D [EC3.1.4.1], putative Get druggable targets OG5_129037 All targets in OG5_129037
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Onchocerca volvulus Glucosylceramidase homolog Get druggable targets OG5_129423 All targets in OG5_129423
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis Get druggable targets OG5_127781 All targets in OG5_127781
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing Get druggable targets OG5_127482 All targets in OG5_127482
Leishmania mexicana pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium knowlesi histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129301 All targets in OG5_129301
Theileria parva leucine aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium parvum GCN5 like acetylase + bromodomain Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania infantum tyrosyl-DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Echinococcus multilocularis transcription factor Dp 1 Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 Get druggable targets OG5_127293 All targets in OG5_127293
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Neospora caninum Bromodomain containing protein, related Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium falciparum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Babesia bovis leucine aminopeptidase, putative Get druggable targets OG5_127293 All targets in OG5_127293
Trypanosoma brucei gambiense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Leishmania mexicana DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Mycobacterium leprae Probable cytosol aminopeptidase PepB Get druggable targets OG5_127293 All targets in OG5_127293
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva histone acetyltransferase Gcn5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Plasmodium yoelii pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum hypothetical protein Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi Pyruvate kinase, M2 isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii histone lysine acetyltransferase GCN5-A Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein Get druggable targets OG5_129423 All targets in OG5_129423
Entamoeba histolytica acetyltransferase, GNAT family Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum Probable cytosol aminopeptidase, related Get druggable targets OG5_127293 All targets in OG5_127293
Toxoplasma gondii histone lysine acetyltransferase GCN5-B Get druggable targets OG5_127781 All targets in OG5_127781
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Schistosoma mansoni tyrosyl-DNA phosphodiesterase Get druggable targets OG5_129037 All targets in OG5_129037
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni DNA polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium parvum phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative Get druggable targets OG5_127781 All targets in OG5_127781
Mycobacterium ulcerans glutaminase Get druggable targets OG5_129245 All targets in OG5_129245
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Pyruvate kinase, muscle isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 Get druggable targets OG5_127781 All targets in OG5_127781
Mycobacterium tuberculosis Probable aminopeptidase PepB Get druggable targets OG5_127293 All targets in OG5_127293
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana Get druggable targets OG5_128521 All targets in OG5_128521
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi O-Glycosyl hydrolase family 30 protein Get druggable targets OG5_129423 All targets in OG5_129423
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium falciparum M17 leucyl aminopeptidase Get druggable targets OG5_127293 All targets in OG5_127293
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase Get druggable targets OG5_129301 All targets in OG5_129301
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii peptidylprolyl isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Toxoplasma gondii pyruvate kinase PyK1 Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis glutaminase, putative Get druggable targets OG5_129245 All targets in OG5_129245
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Neospora caninum Pyruvate kinase (EC 2.7.1.40), related Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 519 aa 23.7 %
Leishmania infantum dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Leishmania infantum acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin reductase 1, cytoplasmic   499 aa 506 aa 23.7 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Neospora caninum glutathione reductase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 32.7 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Plasmodium falciparum thioredoxin reductase Thioredoxin reductase 1, cytoplasmic   499 aa 511 aa 45.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Onchocerca volvulus Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 57.3 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Loa Loa (eye worm) hypothetical protein estrogen receptor 2 (ER beta) 495 aa 418 aa 25.8 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.5 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.6 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, point mutation,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.3 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 540 aa 23.3 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin reductase 1, cytoplasmic   499 aa 464 aa 24.8 %
Leishmania braziliensis dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 488 aa 21.9 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Onchocerca volvulus 4'-phosphopantetheinyl transferase ffp   224 aa 186 aa 26.3 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.2 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Leishmania braziliensis acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 22.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Giardia lamblia U5 small nuclear ribonucleoprotein 200 kDa helicase, putative RecQ helicase-like 649 aa 521 aa 19.8 %
Neospora caninum hypothetical protein Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Leishmania major peptidyl-prolyl cis-trans isomerase, putative peptidylprolyl cis/trans isomerase, NIMA-interacting 1 163 aa 133 aa 27.8 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 518 aa 24.9 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Trypanosoma brucei dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.4 %
Leishmania donovani dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Leishmania major acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 539 aa 22.3 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 460 aa 25.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Trichomonas vaginalis conserved hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 197 aa 22.3 %
Plasmodium falciparum glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 500 aa 32.2 %
Plasmodium berghei dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 26.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Echinococcus granulosus pyruvate kinase pyruvate kinase, muscle 605 aa 521 aa 34.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.9 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 529 aa 31.8 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Entamoeba histolytica hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 198 aa 28.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Echinococcus multilocularis squamous cell carcinoma antigen Human immunodeficiency virus type 1 Tat protein   86 aa 79 aa 30.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Leishmania mexicana 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 452 aa 25.7 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Leishmania braziliensis 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 450 aa 25.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 454 aa 25.3 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Leishmania donovani acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Leishmania mexicana acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 24.4 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 462 aa 25.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0442 0.0571
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0075 0.0113
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1934 0.189
Onchocerca volvulus 0.0024 0.0264 0.048
Treponema pallidum ATP-dependent DNA helicase 0.0012 0.0023 0.0033
Brugia malayi Bromodomain containing protein 0.0051 0.0817 0.1206
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0442 0.0571
Echinococcus granulosus histone acetyltransferase KAT2B 0.0054 0.0896 0.0847
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0586 0.0771
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0266 0.0273
Trypanosoma brucei chrX additional, unordered contigs 0.0014 0.007 0.0062
Loa Loa (eye worm) hypothetical protein 0.004 0.0605 0.0905
Mycobacterium ulcerans glutaminase 0.033 0.6607 1
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0025 0.0297 0.0373
Toxoplasma gondii histone lysine methyltransferase SET1 0.0073 0.128 0.2154
Echinococcus multilocularis dnaJ subfamily B 0.0494 1 1
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.042 0.0574
Loa Loa (eye worm) hypothetical protein 0.0085 0.1539 0.2321
Schistosoma mansoni glucose transporter 0.0015 0.0075 0.0067
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0508 0.0457
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.708 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0436 0.0564
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.0964 0.0915
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0748 0.0762
Loa Loa (eye worm) hypothetical protein 0.0058 0.0967 0.1454
Brugia malayi hypothetical protein 0.003 0.0401 0.0574
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0075 0.0022
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0364 0.055
Echinococcus granulosus pyruvate kinase 0.004 0.0605 0.0554
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0264 0.0388
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.708 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.1422 0.1915
Schistosoma mansoni cpg binding protein 0.0039 0.0578 0.0571
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0047 0.0736 0.1104
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.3341 0.6337
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0075 0.0079
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0165 0.0239
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0241 0.0296
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0194 0.017
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0254 0.1052
Plasmodium vivax glutathione reductase, putative 0.0103 0.1899 0.2108
Trypanosoma brucei glucose transporter 1E 0.0032 0.0442 0.0571
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0442 0.0573
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0165 0.0112
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0441 0.0389
Loa Loa (eye worm) hypothetical protein 0.01 0.1842 0.2779
Echinococcus multilocularis pyruvate kinase 0.004 0.0605 0.0554
Loa Loa (eye worm) hypothetical protein 0.006 0.1017 0.153
Echinococcus granulosus cpg binding protein 0.0039 0.0578 0.0527
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0964 0.0957
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0441 0.0389
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0264 0.0211
Entamoeba histolytica protein kinase, putative 0.0032 0.0441 0.0604
Trypanosoma brucei unspecified product 0.0032 0.0436 0.0564
Brugia malayi hypothetical protein 0.0015 0.0075 0.0079
Plasmodium falciparum proline--tRNA ligase 0.0037 0.0527 0.0514
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0254 0.0268
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.1017 0.151
Plasmodium vivax pyruvate kinase 2, putative 0.0021 0.0199 0.0207
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0736 0.1114
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0241 0.0326
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0266 0.043
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.01 0.1842 0.1836
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.1422 0.1992
Toxoplasma gondii sugar transporter ST1 0.0015 0.0075 0.0104
Leishmania major DNA polymerase eta, putative 0.0045 0.0707 0.0935
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.1422 0.1914
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0313 0.044
Schistosoma mansoni hypothetical protein 0.0025 0.0287 0.0279
Toxoplasma gondii leucyl aminopeptidase LAP 0.0127 0.241 0.4078
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0241 0.0254
Schistosoma mansoni hypothetical protein 0.0019 0.0165 0.0158
Echinococcus granulosus leucine aminopeptidase protein 0.0127 0.241 0.2369
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.1065 0.1427
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0075 0.0113
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0075 0.0079
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.019 0.0225
Echinococcus multilocularis General substrate transporter 0.009 0.163 0.1585
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.0964 0.2259
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0441 0.0478
Echinococcus multilocularis muscleblind protein 1 0.018 0.3507 0.3472
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0264 0.0218
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0254 0.0201
Schistosoma mansoni pyruvate kinase 0.0021 0.0199 0.0192
Trypanosoma cruzi trypanothione reductase, putative 0.0103 0.1899 0.257
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0508 0.0769
Trypanosoma cruzi hexose transporter 0.0032 0.0442 0.0573
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.0964 0.0915
Echinococcus multilocularis solute carrier family 22 0.0015 0.0075 0.0022
Schistosoma mansoni pyruvate kinase 0.004 0.0605 0.0598
Brugia malayi ImpB/MucB/SamB family protein 0.0077 0.1373 0.205
Schistosoma mansoni DNA polymerase eta 0.0077 0.1373 0.1367
Loa Loa (eye worm) thioredoxin reductase 0.0103 0.1899 0.2867
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0508 0.0493
Schistosoma mansoni DNA helicase recq1 0.0024 0.0266 0.0259
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0023 0.0016
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.185 0.1806
Brugia malayi hypothetical protein 0.0024 0.0264 0.0366
Mycobacterium tuberculosis Probable reductase 0.0234 0.4626 0.8936
Schistosoma mansoni hypothetical protein 0.01 0.1842 0.1836
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0264 0.0211
Leishmania major hypothetical protein, conserved 0.0018 0.0153 0.0176
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.708 1
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0127 0.241 0.4585
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.007 0.0062
Entamoeba histolytica hypothetical protein 0.0043 0.0671 0.0929
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.7324 1
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0137 0.0156
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0078 0.1394 0.1347
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.1289 0.1242
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0508 0.0493
Echinococcus granulosus leucyl aminopeptidase 0.0025 0.0297 0.0245
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0364 0.0567
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0508 0.211
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0527 0.0688
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0508 0.0664
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0364 0.0495
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0671 0.062
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0012 0.0025 0.0019
Loa Loa (eye worm) sugar transporter 0.0104 0.1934 0.2919
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0508 0.0663
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.1289 0.1951
Schistosoma mansoni hypothetical protein 0.0043 0.0671 0.0664
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0254 0.0146
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0508 0.0457
Loa Loa (eye worm) hypothetical protein 0.0024 0.0264 0.0388
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0075 0.0071
Echinococcus granulosus pyruvate kinase 0.0021 0.0199 0.0146
Loa Loa (eye worm) hypothetical protein 0.0021 0.0214 0.0313
Loa Loa (eye worm) pyruvate kinase 0.004 0.0605 0.0905
Brugia malayi major facilitator superfamily protein 0.0015 0.0075 0.0079
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.3345 0.455
Trypanosoma brucei glucose transporter, putative 0.0032 0.0442 0.0571
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0025 0.0297 0.0245
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0364 0.055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0213 0.0206
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.272 0.2681
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0197 0.019
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0606 0.0907
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0075 0.0067
Brugia malayi Pyruvate kinase, muscle isozyme 0.004 0.0605 0.0884
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0264 0.028
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0441 0.0417
Schistosoma mansoni protein kinase 0.0032 0.0441 0.0434
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0241 0.0237
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0313 0.044
Mycobacterium ulcerans hypothetical protein 0.0029 0.0364 0.055
Trypanosoma brucei glucose transporter 2A 0.0032 0.0442 0.0571
Brugia malayi Thioredoxin reductase 0.0103 0.1899 0.2849
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0047 0.0736 0.0974
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0441 0.0417
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0441 0.0727
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0047 0.0736 0.0729
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.3341 0.5057
Echinococcus granulosus histone lysine methyltransferase setb 0.0021 0.0213 0.016
Loa Loa (eye worm) RecQ helicase 0.0024 0.0266 0.0392
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0254 0.0408
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0356 0.0551
Loa Loa (eye worm) hypothetical protein 0.0021 0.0214 0.0313
Echinococcus multilocularis cpg binding protein 0.0039 0.0578 0.0527
Trichomonas vaginalis rotamase, putative 0.004 0.0606 0.0758
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0254 0.0384
Plasmodium vivax CDK-related protein kinase 6, putative 0.0444 0.8959 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0012 0.0025 0.0002
Loa Loa (eye worm) MBCTL1 0.0066 0.1129 0.1699
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0364 0.0495
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0232 0.4567 0.4537
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0028 0.0356 0.0502
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0014 0.0006
Brugia malayi glutathione reductase 0.0103 0.1899 0.2849
Schistosoma mansoni hypothetical protein 0.0024 0.0264 0.0257
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0392 0.034
Brugia malayi Bromodomain containing protein 0.0097 0.1776 0.2662
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.3345 0.4549
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0508 0.2028
Brugia malayi hypothetical protein 0.0015 0.0075 0.0079
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0025 0.0297 0.0438
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0266 0.0273
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0586 0.077
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.6229 0.9426
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0736 0.0976
Schistosoma mansoni hypothetical protein 0.0019 0.0165 0.0158
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0441 0.0389
Schistosoma mansoni hypothetical protein 0.01 0.1842 0.1836
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0508 0.0663
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0014 0.007 0.0096
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.01 0.1842 0.2762
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0214 0.0224
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.4008 0.5615
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0261 0.5168 1
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0025 0.0297 0.0373
Schistosoma mansoni glucose transport protein 0.0104 0.1934 0.1928
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0442 0.0523
Echinococcus multilocularis zinc finger protein 0.003 0.039 0.0338
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0508 0.0664
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0707 0.0937
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0241 0.0298
Echinococcus multilocularis dna polymerase kappa 0.0047 0.0736 0.0686
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0025 0.0297 0.0438
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.042 0.0492
Brugia malayi mbt repeat family protein 0.0058 0.0964 0.1428
Schistosoma mansoni terminal deoxycytidyl transferase 0.0047 0.0736 0.0729
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.1289 0.1951
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.1934 0.189
Loa Loa (eye worm) pyruvate kinase-PB 0.0028 0.0353 0.0523
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0025 0.0297 0.0374
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0441 0.0389
Plasmodium falciparum glutathione reductase 0.0036 0.0508 0.0493
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.0736 0.1083
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.042 0.0498
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0021 0.0197 0.0145
Echinococcus granulosus solute carrier family 22 0.0015 0.0075 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.1289 0.1951
Mycobacterium ulcerans hypothetical protein 0.0192 0.3749 0.5674
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.1129 0.1081
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0104 0.1934 0.189
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0103 0.1899 0.3582
Schistosoma mansoni sugar transporter 0.0015 0.0075 0.0067
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0442 0.0573
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0356 0.035
Plasmodium vivax DNA repair protein REV1, putative 0.0014 0.007 0.0063
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0234 0.4626 0.8914
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.4008 0.5615
Trypanosoma cruzi ISWI complex protein 0.0018 0.0153 0.0178
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0671 0.0664
Giardia lamblia Kinase, PLK 0.0116 0.2174 0.3002
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0078 0.1394 0.1347
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0254 0.0261
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0266 0.0331
Schistosoma mansoni rab6-interacting 0.0024 0.0264 0.0257
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0075 0.0079
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0364 0.0464
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0736 0.0974
Brugia malayi hypothetical protein 0.0043 0.0671 0.0983
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.1129 0.1679
Onchocerca volvulus 0.0035 0.0489 0.1053
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0441 0.0478
Trypanosoma brucei glucose transporter, putative 0.0032 0.0442 0.0571
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.1934 0.189
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Entamoeba histolytica deoxycytidyl transferase, putative 0.0047 0.0736 0.1022
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.004 0.0605 0.1041
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0441 0.0522
Echinococcus multilocularis leucyl aminopeptidase 0.0025 0.0297 0.0245
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0508 0.0664
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0441 0.0657
Schistosoma mansoni hypothetical protein 0.0104 0.1934 0.1928
Plasmodium falciparum hexose transporter 0.0104 0.1934 0.2096
Schistosoma mansoni glucose transport protein 0.0104 0.1934 0.1928
Trypanosoma cruzi polo-like protein kinase, putative 0.0116 0.2174 0.2946
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Trypanosoma brucei trypanothione reductase 0.0103 0.1899 0.2568
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0116 0.2174 0.2945
Loa Loa (eye worm) hypothetical protein 0.003 0.0401 0.0596
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0214 0.0887
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.007 0.0062
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0508 0.0553
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0024 0.0266 0.0392
Echinococcus multilocularis leucine aminopeptidase protein 0.0127 0.241 0.2369
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0025 0.0297 0.0415
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0508 0.0842
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.2174 0.2997
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0671 0.062
Schistosoma mansoni hypothetical protein 0.0018 0.0153 0.0146
Schistosoma mansoni sugar transporter 0.0015 0.0075 0.0067
Plasmodium falciparum thioredoxin reductase 0.0103 0.1899 0.2058
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.0964 0.0915
Leishmania major trypanothione reductase 0.0103 0.1899 0.2568
Trypanosoma cruzi DNA polymerase eta, putative 0.0077 0.1373 0.1849
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0436 0.0564
Trypanosoma brucei glucose transporter, putative 0.0032 0.0442 0.0571
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0127 0.241 0.447
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0364 0.0367
Giardia lamblia Pyruvate kinase 0.0021 0.0199 0.0183
Loa Loa (eye worm) hypothetical protein 0.0058 0.0964 0.1449
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0025 0.0297 0.0415
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0356 0.0453
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0075 0.0069
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.0356 0.1475
Loa Loa (eye worm) hypothetical protein 0.0019 0.0165 0.0239
Leishmania major pyruvate kinase 0.004 0.0605 0.0795
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.007 0.0062
Brugia malayi CXXC zinc finger family protein 0.0035 0.0489 0.0707
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0234 0.4626 0.8936
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0508 0.2028
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0401 0.0517
Echinococcus granulosus RUN 0.0024 0.0264 0.0211
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0266 0.0331
Loa Loa (eye worm) hypothetical protein 0.0021 0.0213 0.0311
Loa Loa (eye worm) hypothetical protein 0.0029 0.0364 0.054
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0441 0.0389
Loa Loa (eye worm) hypothetical protein 0.0031 0.042 0.0625
Echinococcus multilocularis pyruvate kinase 0.0032 0.0429 0.0378
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0037 0.0045
Mycobacterium ulcerans pyruvate kinase 0.004 0.0605 0.0916
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.0605 0.1348
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0442 0.0573
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.708 1
Schistosoma mansoni hypothetical protein 0.0355 0.7118 0.7115
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0261 0.5168 1
Loa Loa (eye worm) hypothetical protein 0.018 0.3507 0.5302
Loa Loa (eye worm) hypothetical protein 0.0041 0.0623 0.0933
Mycobacterium ulcerans hypothetical protein 0.0014 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.1289 0.1242
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.0605 0.0797
Entamoeba histolytica protein kinase, putative 0.0032 0.0441 0.0604
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0441 0.057
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0833 0.1109
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0508 0.0663
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.708 1
Loa Loa (eye worm) bromodomain containing protein 0.0026 0.0301 0.0445
Trichomonas vaginalis rotamase, putative 0.0039 0.0586 0.073
Brugia malayi Sugar transporter family protein 0.0015 0.0075 0.0079
Echinococcus multilocularis solute carrier family 22 0.0015 0.0075 0.0022
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0441 0.0657
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.1422 0.1914
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0241 0.0298
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0047 0.0736 0.0944
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.042 0.0368
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0964 0.0957
Echinococcus multilocularis pyruvate kinase 0.0021 0.0199 0.0146
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0527 0.069
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.6229 0.9427
Leishmania major protein kinase, putative 0.0032 0.0441 0.057
Trypanosoma brucei aminopeptidase, putative 0.0025 0.0297 0.0373
Toxoplasma gondii thioredoxin reductase 0.0103 0.1899 0.3209
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.708 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0508 0.0553
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0364 0.0367
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0127 0.241 0.3268
Brugia malayi PHD-finger family protein 0.0036 0.0524 0.076
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.3749 0.7214
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0356 0.0382
Plasmodium falciparum thioredoxin reductase 0.0036 0.0508 0.0493
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0736 0.1114
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0508 0.0663
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.708 1
Loa Loa (eye worm) hypothetical protein 0.018 0.3507 0.5302
Loa Loa (eye worm) hypothetical protein 0.0021 0.0214 0.0313
Plasmodium falciparum pyruvate kinase 0.004 0.0605 0.0602
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0356 0.0582
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0508 0.0663
Echinococcus granulosus leucyl aminopeptidase 0.0025 0.0297 0.0245
Schistosoma mansoni apoptosis regulator bax 0.01 0.1842 0.1836
Echinococcus granulosus pyruvate kinase 0.0021 0.0199 0.0146
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0726 0.0676
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.1934 0.2654
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0982 0.1294
Onchocerca volvulus 0.0024 0.0264 0.048
Schistosoma mansoni bromodomain containing protein 0.0083 0.1483 0.1477
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.007 0.0064
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0489 0.073
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0266 0.0214
Trichomonas vaginalis DNA polymerase eta, putative 0.0047 0.0736 0.0944
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.2174 0.2997
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0356 0.0538
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0736 0.0974
Loa Loa (eye worm) glutaminase 0.033 0.6607 1
Trypanosoma brucei unspecified product 0.0047 0.0736 0.0974
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.708 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0241 0.0365
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0165 0.0112
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1934 0.189
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0356 0.0321
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0116 0.2174 0.3283
Loa Loa (eye worm) pyruvate kinase 0.004 0.0605 0.0905
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0508 0.0501
Treponema pallidum NADH oxidase 0.0036 0.0508 0.0718
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0266 0.0221
Trypanosoma brucei pyruvate kinase 1, putative 0.004 0.0605 0.0795
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.1129 0.1081
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Giardia lamblia Hexose transporter 0.0015 0.0075 0.0006
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.1422 0.1376
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.042 0.0602
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0508 0.0664
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0264 0.0211
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0527 0.069
Chlamydia trachomatis cytosol aminopeptidase 0.0127 0.241 1
Schistosoma mansoni cpg binding protein 0.0035 0.0489 0.0482
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0376 0.0324
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0508 0.0851
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0364 0.055
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.2174 0.2997
Schistosoma mansoni ap endonuclease 0.0023 0.0241 0.0234
Schistosoma mansoni DNA helicase recq5 0.0024 0.0266 0.0259
Loa Loa (eye worm) hypothetical protein 0.0029 0.0364 0.054
Schistosoma mansoni DNA polymerase IV / kappa 0.0014 0.007 0.0063
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.3294 0.3258
Brugia malayi serine/threonine-protein kinase plk-2 0.0116 0.2174 0.3267
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0356 0.0582
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0038 0.0022
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0441 0.0727
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0075 0.0005
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0075 0.0069
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.2174 0.2997
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0441 0.0478
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0508 0.0663
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0254 0.0313
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0025 0.0297 0.0373
Loa Loa (eye worm) hypothetical protein 0.0066 0.1129 0.1699
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0254 0.0246
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0181 0.0208
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.708 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0241 0.0244
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0508 0.0664
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.4008 0.5615
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0508 0.0664
Loa Loa (eye worm) hypothetical protein 0.0021 0.0214 0.0313
Leishmania major glucose transporter, lmgt1 0.0032 0.0442 0.0571
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0254 0.035
Schistosoma mansoni hypothetical protein 0.0014 0.0054 0.0046
Schistosoma mansoni kinase 0.006 0.1013 0.1006
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.1129 0.1122
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.6229 0.8786
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0241 0.0189
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0054 0.0896 0.1501
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.042 0.0602
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0364 0.055
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.019 0.0225
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.0605 0.1348
Loa Loa (eye worm) hypothetical protein 0.0053 0.0878 0.132
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0508 0.0663
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0025 0.0297 0.0415
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.4008 1
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0508 0.0664
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Brugia malayi Doublecortin family protein 0.0024 0.0264 0.0366
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0169 0.3274 0.5548
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0127 0.241 0.3269
Schistosoma mansoni hypothetical protein 0.0041 0.0623 0.0616
Entamoeba histolytica hypothetical protein 0.0043 0.0671 0.0929
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0075 0.0102
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.01 0.1842 0.1798
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0964 0.0957
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0197 0.019
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.7324 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0376 0.0324
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.0527 0.0574
Leishmania major glucose transporter, lmgt3 0.0032 0.0442 0.0571
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.1289 0.1283
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.01 0.1842 0.1798
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0264 0.0211
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.0527 0.0874
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0606 0.0885
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0508 0.0625
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0075 0.0022
Echinococcus multilocularis solute carrier family 22 0.0015 0.0075 0.0022
Plasmodium falciparum glutathione reductase 0.0103 0.1899 0.2058
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.6229 0.8786
Leishmania major DNA polymerase kappa, putative 0.0014 0.007 0.0062
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0127 0.241 0.3268
Loa Loa (eye worm) hypothetical protein 0.0077 0.1373 0.2069
Trypanosoma brucei sugar transporter, putative 0.0015 0.0075 0.0069
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0047 0.0736 0.0686
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0024 0.0266 0.0214
Loa Loa (eye worm) glutaminase 2 0.033 0.6607 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0054 0.0896 0.1172
Trypanosoma brucei glucose transporter, putative 0.0032 0.0442 0.0571
Schistosoma mansoni lipoxygenase 0.0142 0.272 0.2715
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0508 0.0664
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0241 0.0189
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0025 0.0297 0.0374
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0127 0.241 1
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.2174 0.2997
Loa Loa (eye worm) hypothetical protein 0.0024 0.0264 0.0388
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0241 0.0341
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0401 0.0659
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0266 0.0369
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.1294 0.1288
Loa Loa (eye worm) hypothetical protein 0.0028 0.0353 0.0523
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0442 0.0523
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0075 0.0102
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0364 0.0517
Plasmodium vivax hexose transporter 0.0104 0.1934 0.2146
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0442 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0442 0.0523
Onchocerca volvulus Serine\/threonine kinase homolog 0.0116 0.2174 0.5337
Schistosoma mansoni ap endonuclease 0.0023 0.0241 0.0234
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0127 0.241 0.2679
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0669 0.0619
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0508 0.0769
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0508 0.0842
Schistosoma mansoni cpg binding protein 0.0039 0.0578 0.0571
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0441 0.0417
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0012 0.0023 0.0011
Schistosoma mansoni rab6-interacting 0.0024 0.0264 0.0257
Chlamydia trachomatis pyruvate kinase 0.004 0.0605 0.2511
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.1289 0.1283
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.2174 0.2169
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0254 0.0384
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0364 0.0495
Echinococcus multilocularis GPCR, family 2 0.0019 0.0165 0.0112
Echinococcus granulosus dna polymerase kappa 0.0047 0.0736 0.0686
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.4008 0.5615
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.4237 0.5941
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0075 0.0071
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0045 0.0707 0.118
Entamoeba histolytica hypothetical protein 0.0023 0.0254 0.0339
Plasmodium vivax sugar transporter, putative 0.0015 0.0075 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.007 0.0062
Schistosoma mansoni glutaminase 0.033 0.6607 0.6605
Echinococcus multilocularis leucyl aminopeptidase 0.0025 0.0297 0.0245
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.01 0.1842 0.1798
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0401 0.0372
Echinococcus granulosus expressed protein 0.004 0.0606 0.0556
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0028 0.0356 0.1387
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.1422 0.1915
Brugia malayi Sugar transporter family protein 0.0015 0.0075 0.0079
Echinococcus granulosus solute carrier family 22 0.0015 0.0075 0.0022
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0254 0.0313
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.6229 0.8786
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0178 0.3455 0.345
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0748 0.0967
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.708 1
Trypanosoma cruzi ISWI complex protein 0.0018 0.0153 0.0178
Loa Loa (eye worm) glutathione reductase 0.0103 0.1899 0.2867
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0015 0.0075 0.021
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.1017 0.153
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0508 0.0737
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.185 0.2775
Brugia malayi hypothetical protein 0.0024 0.0264 0.0366
Trypanosoma brucei glucose transporter, putative 0.0032 0.0442 0.0571
Trypanosoma brucei unspecified product 0.0032 0.0436 0.0564
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0023 0.0016
Brugia malayi Sugar transporter family protein 0.0104 0.1934 0.2902
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0287 0.0423
Schistosoma mansoni hypothetical protein 0.0019 0.0165 0.0158
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0024 0.0266 0.0221
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0736 0.0976
Echinococcus granulosus General substrate transporter 0.009 0.163 0.1585
Trypanosoma brucei ISWI complex protein 0.0018 0.0153 0.0176
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0254 0.0255
Entamoeba histolytica recQ family DNA helicase 0.0012 0.0023 0.0014
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.042 0.0412
Schistosoma mansoni polycystin 1-related 0.0024 0.0264 0.0257
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0356 0.0453
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0266 0.0358
Loa Loa (eye worm) hypothetical protein 0.0023 0.0254 0.0373
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0214 0.0273
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0401 0.0372
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0364 0.0567
Echinococcus granulosus pyruvate kinase 0.004 0.0605 0.0554
Schistosoma mansoni hypothetical protein 0.0019 0.0165 0.0158
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Echinococcus granulosus methyl CpG binding domain protein 2 0.0021 0.0197 0.0145
Toxoplasma gondii pyruvate kinase PyK1 0.004 0.0605 0.1006
Plasmodium falciparum protein kinase 6 0.0444 0.8959 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0021 0.0213 0.016
Leishmania major hypothetical protein, conserved 0.0015 0.0075 0.0069
Loa Loa (eye worm) hypothetical protein 0.0029 0.0364 0.054
Mycobacterium tuberculosis Probable oxidoreductase 0.0261 0.5168 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0298 0.044
Trypanosoma brucei glucose transporter, putative 0.0032 0.0442 0.0571
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.019 0.0225
Echinococcus granulosus dna polymerase eta 0.0077 0.1373 0.1327
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0214 0.0161
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0833 0.1107
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0442 0.0523
Loa Loa (eye worm) pyruvate kinase 0.004 0.0605 0.0905
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0264 0.0211
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0441 0.0727
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0441 0.0434
Giardia lamblia Sgs1 DNA helicase, putative 0.0024 0.0266 0.028
Echinococcus multilocularis RUN 0.0024 0.0264 0.0211
Toxoplasma gondii hypothetical protein 0.0059 0.0989 0.166
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.708 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0047 0.0736 0.1298
Echinococcus granulosus thioredoxin glutathione reductase 0.0103 0.1912 0.1868
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.0605 0.0797
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.272 0.2681
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0261 0.5168 1
Brugia malayi cytosol aminopeptidase 0.0025 0.0297 0.0415
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0266 0.0333
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0508 0.0769
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0075 0.0022
Loa Loa (eye worm) hypothetical protein 0.0024 0.0266 0.0392
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0127 0.241 0.3269
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0736 0.1298
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0364 0.0464
Schistosoma mansoni sugar transporter 0.0015 0.0075 0.0067
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.1129 0.1081
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Loa Loa (eye worm) sugar transporter 0.0015 0.0075 0.0102
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0364 0.0517
Plasmodium falciparum protein kinase 7 0.0295 0.589 0.6547
Loa Loa (eye worm) hypothetical protein 0.0031 0.042 0.0625
Schistosoma mansoni zinc finger protein 0.0018 0.0153 0.0146
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1934 0.189
Loa Loa (eye worm) hypothetical protein 0.0046 0.073 0.1095
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0364 0.055
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1934 0.189
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0014 0.007 0.0096
Giardia lamblia Sugar-proton symporter 0.0015 0.0075 0.0006
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0527 0.0688
Leishmania major pyruvate kinase 0.004 0.0605 0.0795
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.1934 0.189
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0392 0.034
Schistosoma mansoni protein kinase 0.0032 0.0441 0.0434
Echinococcus multilocularis expressed protein 0.004 0.0606 0.0556
Toxoplasma gondii facilitative glucose transporter GT1 0.0104 0.1934 0.3268
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.0605 0.0757
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Toxoplasma gondii pyruvate kinase PyKII 0.0021 0.0199 0.0315
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.007 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.6229 0.8786
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0266 0.0369
Echinococcus multilocularis dna polymerase eta 0.0077 0.1373 0.1327
Mycobacterium tuberculosis Probable dehydrogenase 0.0234 0.4626 0.8936
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0833 0.1109
Trypanosoma brucei pyruvate kinase 1 0.004 0.0605 0.0795
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0054 0.0896 0.1172
Trypanosoma brucei polo-like protein kinase 0.0116 0.2174 0.2945
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0075 0.0104
Loa Loa (eye worm) acetyltransferase 0.0178 0.3455 0.5223
Brugia malayi Cam kinase protein 1 0.0032 0.0441 0.0634
Loa Loa (eye worm) hypothetical protein 0.0014 0.007 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.0982 0.1294
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0169 0.3274 0.3644
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0736 0.0976
Onchocerca volvulus 0.01 0.185 0.4513
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0606 0.0758
Schistosoma mansoni lipoxygenase 0.01 0.1833 0.1827
Brugia malayi glutaminase DH11.1 0.033 0.6607 1
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0527 0.0688
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0241 0.0237
Echinococcus granulosus solute carrier family 22 0.0015 0.0075 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.4237 0.5941
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0025 0.0002
Plasmodium falciparum pyruvate kinase 2 0.0021 0.0199 0.0145
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.0964 0.0915
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.1422 0.1415
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.4008 0.5615
Trypanosoma brucei glucose transporter, putative 0.0032 0.0442 0.0571
Toxoplasma gondii sugar transporter ST3 0.0015 0.0075 0.0104
Schistosoma mansoni zinc finger protein 0.003 0.039 0.0383
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0254 0.0201
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0241 0.0907
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0736 0.0976
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0441 0.0417
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.1422 0.1376
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0376 0.0368
Entamoeba histolytica hypothetical protein 0.0028 0.0356 0.0484
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0024
Echinococcus multilocularis pyruvate kinase 0.0021 0.0199 0.0146
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0748 0.1039
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.4008 0.5615
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0254 0.0246
Brugia malayi hypothetical protein 0.0015 0.0075 0.0079
Onchocerca volvulus 0.0029 0.0364 0.0734
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0266 0.0369
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0508 0.0664
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0266 0.043
Entamoeba histolytica hypothetical protein 0.0043 0.0671 0.0929
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0442 0.0523
Leishmania major DNA damage repair protein, putative 0.0014 0.007 0.0062
Mycobacterium ulcerans sugar transporter 0.0015 0.0075 0.0113
Schistosoma mansoni rotamase 0.004 0.0606 0.0599
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0024 0.0266 0.0214
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0964 0.1449
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0165 0.0112
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0047 0.0736 0.0686
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0165 0.0216
Brugia malayi major facilitator superfamily protein 0.0015 0.0075 0.0079
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0024 0.0266 0.0214
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0401 0.0433
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0508 0.0619
Toxoplasma gondii sugar transporter ST2 0.0015 0.0075 0.0104
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0364 0.0464
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.1422 0.2124
Trypanosoma cruzi polo-like protein kinase, putative 0.0116 0.2174 0.2946
Leishmania major glucose transporter, lmgt2 0.0032 0.0442 0.0571
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0726 0.0676
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0075 0.0113
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0401 0.0517
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.1289 0.1732
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0441 0.0478
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.708 1
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.007 0.0064
Plasmodium falciparum mitogen-activated protein kinase 2 0.0169 0.3274 0.3604
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0441 0.0389
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.007 0.0062
Loa Loa (eye worm) apoptosis regulator protein 0.01 0.1842 0.2779
Schistosoma mansoni leucine aminopeptidase 0.0025 0.0297 0.0289
Loa Loa (eye worm) hypothetical protein 0.0021 0.0214 0.0313
Entamoeba histolytica hypothetical protein 0.0043 0.0671 0.0929
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0508 0.0619
Loa Loa (eye worm) hypothetical protein 0.01 0.185 0.2792
Plasmodium vivax pyruvate kinase, putative 0.004 0.0605 0.0661
Brugia malayi Muscleblind-like protein 0.018 0.3507 0.5291
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.185 0.1844
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.1289 0.2171
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.1017 0.151
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0364 0.0517
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0024 0.0266 0.0214
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0401 0.0516
Leishmania major DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0116 0.2174 0.2132
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0586 0.081
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0736 0.0974
Brugia malayi hypothetical protein 0.002 0.0178 0.0235
Toxoplasma gondii protein kinase, putative 0.0295 0.589 1
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0736 0.0974
Leishmania major DNA polymerase eta, putative 0.0077 0.1373 0.1847
Echinococcus multilocularis solute carrier family 22 0.0015 0.0075 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0024
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.0605 0.0757
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.1289 0.2384
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0441 0.0634
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0234 0.4626 0.8936
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.4008 0.5615
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0234 0.4626 0.8936
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0165 0.0112
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.7324 1
Schistosoma mansoni hypothetical protein 0.0494 1 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0241 0.0296
Schistosoma mansoni loxhd1 0.0024 0.0264 0.0257
Echinococcus granulosus pyruvate kinase 0.0021 0.0199 0.0146
Schistosoma mansoni protein kinase 0.0032 0.0441 0.0434
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.2174 0.2997
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0165 0.0216
Echinococcus granulosus muscleblind protein 0.018 0.3507 0.3472
Mycobacterium leprae Probable pyruvate kinase PykA 0.004 0.0605 0.0851
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.042 0.0479
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0356 0.0538
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0241 0.0354
Brugia malayi polk-prov protein 0.0014 0.007 0.0072
Plasmodium vivax thioredoxin reductase, putative 0.0103 0.1899 0.2108
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0441 0.0417
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0364 0.055
Loa Loa (eye worm) hypothetical protein 0.0032 0.0441 0.0657
Entamoeba histolytica pyruvate kinase, putative 0.0028 0.0353 0.0479
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0181 0.0208
Trypanosoma brucei DNA polymerase eta, putative 0.0077 0.1373 0.1847
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0178 0.3455 0.342
Brugia malayi mbt repeat family protein 0.0058 0.0964 0.1428
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.007 0.0062
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.042 0.0412
Schistosoma mansoni glucose transport protein 0.0104 0.1934 0.1928
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0441 0.0389
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.185 0.1806
Echinococcus granulosus solute carrier family 22 0.0015 0.0075 0.0022
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.3345 0.4549
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0442 0.0523
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0025 0.0297 0.0289
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0442 0.0571
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0364 0.055
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.1129 0.1081
Leishmania major hypothetical protein, conserved 0.003 0.0401 0.0516
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.3341 0.6414
Echinococcus multilocularis pyruvate kinase 0.0021 0.0199 0.0146
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0054 0.0896 0.0986
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.01 0.1842 0.1798
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0833 0.1109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0213 0.0206
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0266 0.0273
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0241 0.0322
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0075 0.0022
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0254 0.0206
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0586 0.077
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.042 0.0368
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0586 0.0975
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0234 0.4626 0.8936
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.7324 1
Toxoplasma gondii exonuclease III APE 0.0023 0.0241 0.0387
Echinococcus granulosus zinc finger protein 0.003 0.039 0.0338
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.019 0.0225
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0669 0.0619
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0264 0.0211
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0025 0.0297 0.0373
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0623 0.0911
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0075 0.0071
Giardia lamblia Pyruvate kinase 0.004 0.0605 0.0763
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0116 0.2174 0.2132
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0232 0.4567 0.4537
Schistosoma mansoni hypothetical protein 0.01 0.1842 0.1836
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.0605 0.1348
Schistosoma mansoni sugar transporter 0.0015 0.0075 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0436 0.0564
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0054 0.0896 0.1501
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0241 0.0331
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.1422 0.2143
Giardia lamblia DINP protein human, muc B family 0.0047 0.0736 0.095
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.6229 0.8786
Onchocerca volvulus 0.0058 0.0964 0.2259
Echinococcus multilocularis thioredoxin glutathione reductase 0.0103 0.1912 0.1868
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0586 0.0771
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0441 0.0389
Trichomonas vaginalis glutaminase, putative 0.033 0.6607 0.9325
Echinococcus multilocularis pyruvate kinase 0.004 0.0605 0.0554
Brugia malayi acetyltransferase, GNAT family protein 0.0178 0.3455 0.5212
Brugia malayi Pyruvate kinase, M2 isozyme 0.004 0.0605 0.0884
Plasmodium falciparum M17 leucyl aminopeptidase 0.0127 0.241 0.2632
Echinococcus multilocularis leucyl aminopeptidase 0.0025 0.0297 0.0245
Mycobacterium ulcerans leucyl aminopeptidase 0.0127 0.241 0.3648
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0508 0.0663
Echinococcus granulosus GPCR family 2 0.0019 0.0165 0.0112
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0254 0.0315
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0214 0.0324
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0241 0.0192
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0102
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.007 0.0064
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0025 0.0297 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0116 0.2174 0.2997
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.6229 0.8786
Echinococcus multilocularis muscleblind protein 0.018 0.3507 0.3472
Echinococcus granulosus bloom syndrome protein 0.0024 0.0266 0.0214
Entamoeba histolytica serine/threonine protein kinase, putative 0.0116 0.2174 0.3058
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0442 0.0571
Schistosoma mansoni pyruvate kinase 0.004 0.0605 0.0598
Trypanosoma brucei glucose transporter, putative 0.0032 0.0442 0.0571

Activities

Activity type Activity value Assay description Source Reference
AC50 (binding) = 160.253 uM PUBCHEM_BIOASSAY: C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504431] ChEMBL. No reference
IC50 (binding) = 2.002210664 um PUBCHEM_BIOASSAY: Estrogen Receptor-beta Coactivator Binding Inhibitors ELISA Secondary Assay. (Class of assay: confirmatory) [Related pubchem assays: 633 (Primary screen preceding this ELISA dose response confirmation assay.), 733 (Primary dose response assay preceding this ELISA dose response confirmation assay.)] ChEMBL. No reference
IC50 (functional) = 4.923883117 um PUBCHEM_BIOASSAY: Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 1022 (Primary screen preceding this dose-response assay.)] ChEMBL. No reference
IC50 (functional) 6.433 uM PubChem BioAssay. An HIV-1 Tat-TAR Fluorescence Polarization (FP) Counter Screen to evaluate Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 18.92 um PUBCHEM_BIOASSAY: Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP). (Class of assay: confirmatory) ChEMBL. No reference
Max_Activity_Concent (functional) 50 uM PubChem BioAssay. Thermal shift assay to identify compound binding to Kelch domain of Keap1 protein Measured in Biochemical System Using RT-PCR - 2119-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
Max_Concentration (binding) 50 uM PubChem BioAssay. Counterscreen to eliminate false positive from thermal shift assay Measured in Biochemical System Using Plate Reader - 2119-07_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.0029 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.0928 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 1.122 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.5849 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) = 1.7783 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 2.5119 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 2.6679 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485292] ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) 2.8184 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (binding) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) [Related pubchem assays: 1705 (qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) ), 2324 (Probe Development Summary of Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1707 (Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay), 2517 (qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1708 (Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV)] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 7.9245 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 12.5893 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.4591 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.2117 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2: Hit confirmation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 18.8876 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.0115 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) = 25.1189 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 26.8545 uM PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488768, AID492961] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay to Find Inhibitors of Phosphoglycerate Kinase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Primary screen confirmation. (Class of assay: confirmatory) [Related pubchem assays: 2451, 2472, 2464 ] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1476 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent))] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 56.2341 uM PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) = 199.5262 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Coupling assay counterscreen confirmation. (Class of assay: confirmatory) [Related pubchem assays: 2451, 2472, 2464 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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