Detailed information for compound 1526370

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 551.611 | Formula: C28H29N3O7S
  • H donors: 3 H acceptors: 6 LogP: 2.98 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: CN1Cc2ccccc2[C@H](N=C1OCc1ccc(cc1)NS(=O)(=O)C)c1ccccc1.OC(=O)/C=C/C(=O)O
  • InChi: 1S/C24H25N3O3S.C4H4O4/c1-27-16-20-10-6-7-11-22(20)23(19-8-4-3-5-9-19)25-24(27)30-17-18-12-14-21(15-13-18)26-31(2,28)29;5-3(6)1-2-4(7)8/h3-15,23,26H,16-17H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t23-;/m1./s1
  • InChiKey: BSGONBKDBGMBNS-RNCYCKTQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0132 0.0457 0.0468
Echinococcus granulosus low density lipoprotein receptor protein 0.0196 0.0809 0.0833
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0374 0.1802 0.1863
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0205 0.1336
Echinococcus granulosus Vam6:Vps39 protein 0.0119 0.0386 0.0395
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0504 0.2524 0.261
Schistosoma mansoni protein kinase C mu 0.023 0.1 0.1032
Loa Loa (eye worm) RNA binding protein 0.0065 0.0082 0.0082
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0125 0.0418 0.0425
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0533 0.3572
Schistosoma mansoni protein kinase 0.0075 0.0136 0.0136
Echinococcus multilocularis neuroglian 0.008 0.0169 0.017
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0124 0.0413 0.0419
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0128 0.0128
Trichomonas vaginalis AGC family protein kinase 0.0143 0.0516 0.3457
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0196 0.0811 0.0811
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0052 0.0013 0.0008
Echinococcus multilocularis tyrosine kinase 0.0081 0.0173 0.0174
Brugia malayi Temporarily assigned gene name protein 59 0.0119 0.0386 0.039
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0212 0.09 0.0928
Toxoplasma gondii microneme protein MIC4 0.0282 0.129 0.1328
Entamoeba histolytica p21-activated kinase 0.0137 0.0486 0.2434
Brugia malayi hypothetical protein 0.0504 0.2524 0.2553
Schistosoma mansoni serine/threonine protein kinase 0.027 0.1223 0.1262
Echinococcus granulosus mitogen activated protein kinase 14 0.0168 0.0653 0.0671
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0413 0.0423
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0389 0.1887 0.195
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0105 0.0307 0.0309
Brugia malayi Protein kinase domain containing protein 0.0389 0.1887 0.1908
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.062 0.4166
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0809
Schistosoma mansoni Neurotrimin precursor (hNT) 0.006 0.0057 0.0054
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Onchocerca volvulus 0.0062 0.0069 0.0066
Loa Loa (eye worm) hypothetical protein 0.0196 0.0809 0.0809
Entamoeba histolytica hypothetical protein 0.0128 0.0434 0.217
Loa Loa (eye worm) hypothetical protein 0.1074 0.5691 0.5691
Echinococcus multilocularis protein jagged 1 0.014 0.0502 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0268 0.1764
Schistosoma mansoni notch 0.014 0.0502 0.0515
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0084 0.0188 0.0189
Echinococcus granulosus nervana 2 0.0132 0.0457 0.0468
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0286 0.1313 0.1313
Echinococcus multilocularis neurogenic locus protein delta 0.014 0.0502 0.0515
Brugia malayi Calcium binding EGF domain containing protein 0.0357 0.1704 0.1723
Loa Loa (eye worm) hypothetical protein 0.0172 0.0675 0.0675
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0109 0.0326 0.0333
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.014 0.0502 0.0508
Brugia malayi Protein kinase c protein 2 0.0121 0.0395 0.0399
Loa Loa (eye worm) hypothetical protein 0.0248 0.11 0.11
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0075 0.0141 0.0141
Giardia lamblia Kinase, CMGC MAPK 0.0087 0.0205 0.1504
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Brugia malayi P21-Rho-binding domain containing protein 0.0051 0.0005 0.0005
Brugia malayi protein-tyrosine kinase 0.0144 0.0521 0.0527
Loa Loa (eye worm) hypothetical protein 0.0216 0.0921 0.0921
Echinococcus granulosus N chimaerin 0.0084 0.0188 0.0189
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0336 0.1588 0.1588
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Loa Loa (eye worm) hypothetical protein 0.0363 0.1742 0.1742
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0196 0.0809 0.0833
Schistosoma mansoni protein kinase 0.0389 0.1887 0.195
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0458 0.3062
Echinococcus granulosus protein kinase 0.0161 0.0617 0.0635
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0171 0.0675 0.0694
Echinococcus multilocularis mitogen activated protein kinase 3 0.0087 0.0205 0.0207
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0119 0.0385 0.0385
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0087 0.0205 0.1336
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0075 0.0136 0.0132
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0509 0.0522
Loa Loa (eye worm) TK protein kinase 0.0366 0.1758 0.1758
Echinococcus multilocularis dual specificity 0.0146 0.0533 0.0547
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Plasmodium vivax unspecified product 0.0104 0.0302 0.0304
Echinococcus multilocularis cyclin dependent kinase 1 0.0124 0.0413 0.0423
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0239 0.0242
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0162 0.062 0.0634
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0119 0.0386 0.0391
Onchocerca volvulus 0.0068 0.0102 0.01
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.008 0.0166 0.0168
Trypanosoma brucei aurora B kinase 0.0153 0.0572 0.3836
Giardia lamblia Kinase, AGC AKT 0.0123 0.0403 0.3022
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0081 0.0172 0.0169
Loa Loa (eye worm) protein kinase domain-containing protein 0.0225 0.0974 0.0974
Brugia malayi hypothetical protein 0.0235 0.1028 0.1039
Echinococcus multilocularis tyrosine protein kinase 0.0298 0.138 0.1425
Brugia malayi Suppressor of lurcher protein 1 precursor 0.0132 0.0457 0.0462
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0241 0.106 0.1094
Trichomonas vaginalis AGC family protein kinase 0.0153 0.0572 0.3836
Loa Loa (eye worm) hypothetical protein 0.1787 0.9655 0.9655
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0166 0.0167
Onchocerca volvulus 0.0132 0.0457 0.0468
Echinococcus multilocularis mitogen activated protein kinase 11 0.0168 0.0653 0.0671
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0082 0.008
Schistosoma mansoni vesicular amine transporter 0.006 0.0057 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0141 0.0902
Brugia malayi CUB domain containing protein 0.0132 0.0457 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Loa Loa (eye worm) hypothetical protein 0.0093 0.0239 0.0239
Onchocerca volvulus 0.1074 0.5691 0.5892
Schistosoma mansoni tyrosine kinase 0.0083 0.0184 0.0186
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0353 0.2345
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0153 0.0572 0.287
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0356 0.1701 0.1701
Onchocerca volvulus 0.0282 0.129 0.1331
Plasmodium falciparum protein serine/threonine kinase-1 0.0162 0.062 0.0634
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0075 0.0141 0.0137
Schistosoma mansoni protein kinase 0.0204 0.0853 0.0879
Brugia malayi casein kinase 1, delta 0.0114 0.0353 0.0357
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0142 0.051 0.3417
Brugia malayi zinc metalloproteinase toh-2 precursor 0.0132 0.0457 0.0462
Echinococcus multilocularis expressed conserved protein 0.0141 0.0507 0.052
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0818
Onchocerca volvulus 0.0504 0.2524 0.261
Trichomonas vaginalis AGC family protein kinase 0.0316 0.1477 1
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Entamoeba histolytica casein kinase, putative 0.0104 0.0302 0.1505
Trichomonas vaginalis STE family protein kinase 0.0131 0.0449 0.2998
Trypanosoma brucei protein kinase, putative 0.0087 0.0205 0.1336
Entamoeba histolytica protein kinase domain containing protein 0.0146 0.0533 0.2674
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0818
Echinococcus granulosus snurportin 1 0.027 0.1222 0.1261
Echinococcus granulosus fibropellin Ia 0.014 0.0502 0.0515
Echinococcus granulosus expressed protein 0.0142 0.051 0.0524
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0146 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.006 0.0057 0.0057
Brugia malayi Nematode astacin protease protein 30 0.0132 0.0457 0.0462
Plasmodium falciparum glycogen synthase kinase 3 0.0135 0.0472 0.048
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0251 0.0255
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Echinococcus granulosus tyrosine protein kinase Blk 0.0144 0.0521 0.0535
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0302 0.1999
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Schistosoma mansoni protein kinase 0.0153 0.0572 0.0587
Loa Loa (eye worm) TK protein kinase 0.0274 0.1245 0.1245
Loa Loa (eye worm) hypothetical protein 0.0077 0.015 0.015
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.1197 0.1235
Loa Loa (eye worm) hypothetical protein 0.0197 0.0819 0.0819
Echinococcus multilocularis casein kinase i 0.0114 0.0353 0.0361
Brugia malayi Protein kinase domain containing protein 0.0336 0.1588 0.1606
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0254 0.1133 0.1169
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.062 0.0638
Toxoplasma gondii PAN domain-containing protein 0.0282 0.129 0.1328
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0075 0.0141 0.0137
Loa Loa (eye worm) hypothetical protein 0.006 0.0057 0.0057
Brugia malayi Cadherin domain containing protein 0.014 0.0502 0.0508
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0818
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0153 0.0572 0.287
Brugia malayi Low-density lipoprotein receptor-related protein, putative 0.0196 0.0809 0.0818
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0705 0.0726
Trichomonas vaginalis AGC family protein kinase 0.0316 0.1477 1
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0818
Trichomonas vaginalis CAMK family protein kinase 0.0286 0.1313 0.8886
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0265 0.1194 0.1228
Loa Loa (eye worm) AGC/PKA protein kinase 0.0075 0.0141 0.0141
Schistosoma mansoni protein kinase 0.0084 0.0186 0.0188
Toxoplasma gondii microneme protein, putative 0.0282 0.129 0.1328
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0191 0.1245
Schistosoma mansoni tyrosine kinase 0.0093 0.0238 0.0242
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0413 0.2756
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0413 0.2756
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0991 0.1022
Trichomonas vaginalis CAMK family protein kinase 0.012 0.0391 0.2605
Loa Loa (eye worm) hypothetical protein 0.0132 0.0457 0.0457
Schistosoma mansoni slit 0.0141 0.0504 0.0517
Schistosoma mansoni hypothetical protein 0.0132 0.0457 0.0468
Loa Loa (eye worm) DPY-31 protein 0.0132 0.0457 0.0457
Onchocerca volvulus 0.0081 0.0173 0.0173
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0075 0.0141 0.0137
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0267 0.1205 0.1205
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0196 0.0809 0.0833
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0062 0.0067 0.0064
Onchocerca volvulus Serine\/threonine kinase homolog 0.0286 0.1313 0.1355
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0205 0.1336
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0119 0.0386 0.0395
Loa Loa (eye worm) trypsin family protein 0.0504 0.2524 0.2524
Onchocerca volvulus 0.0282 0.129 0.1331
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0214 0.0911 0.0939
Loa Loa (eye worm) hypothetical protein 0.0489 0.2439 0.2439
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0082 0.0082
Echinococcus multilocularis 0.0161 0.0617 0.0635
Schistosoma mansoni tyrosine kinase 0.0296 0.1369 0.1413
Trypanosoma cruzi casein kinase, putative 0.0114 0.0353 0.0357
Brugia malayi Immunoglobulin I-set domain containing protein 0.0452 0.2232 0.2257
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0251 0.0255
Plasmodium vivax glycogen synthase kinase 3, putative 0.0135 0.0472 0.048
Schistosoma mansoni serine/threonine kinase 0.0177 0.0705 0.0726
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0114 0.0353 0.0357
Echinococcus multilocularis notch 0.014 0.0502 0.0515
Schistosoma mansoni tyrosine kinase 0.0422 0.2067 0.2137
Loa Loa (eye worm) hypothetical protein 0.0098 0.0268 0.0268
Onchocerca volvulus 0.079 0.411 0.4254
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0504 0.2524 0.261
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0084 0.0189 0.0187
Schistosoma mansoni hypothetical protein 0.0132 0.0457 0.0468
Echinococcus multilocularis low density lipoprotein receptor protein 0.0196 0.0809 0.0833
Schistosoma mansoni serine/threonine-protein kinase 0.0171 0.0675 0.0694
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0974 0.1005
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0205 0.1336
Schistosoma mansoni hypothetical protein 0.0119 0.0386 0.0395
Onchocerca volvulus 0.0069 0.0108 0.0106
Plasmodium vivax serine/threonine protein kinase, putative 0.0142 0.051 0.052
Leishmania major mitochondrial DNA polymerase beta 0.0265 0.1194 0.1228
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Brugia malayi Protein kinase domain containing protein 0.0212 0.09 0.091
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0251 0.0255
Echinococcus granulosus neuroglian 0.008 0.0169 0.017
Mycobacterium ulcerans hypothetical protein 0.0109 0.0326 0.0343
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Schistosoma mansoni rap gtpase-activating protein 0.0119 0.0386 0.0395
Echinococcus multilocularis activin receptor type 0.0075 0.0136 0.0136
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0135 0.0472 0.048
Echinococcus multilocularis epidermal growth factor receptor 0.0338 0.1602 0.1655
Loa Loa (eye worm) hypothetical protein 0.0493 0.2464 0.2464
Loa Loa (eye worm) hypothetical protein 0.0196 0.0809 0.0809
Trichomonas vaginalis AGC family protein kinase 0.0316 0.1477 1
Trypanosoma cruzi Protein kinase B 0.0171 0.0675 0.0691
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0165 0.0638 0.0652
Brugia malayi Nematode astacin protease protein 30 0.0132 0.0457 0.0462
Brugia malayi Protein kinase domain containing protein 0.0229 0.0997 0.1008
Schistosoma mansoni hypothetical protein 0.0109 0.0327 0.0334
Brugia malayi Protein kinase domain containing protein 0.0177 0.0705 0.0713
Onchocerca volvulus 0.0345 0.1639 0.1693
Brugia malayi Fes/CIP4 homology domain containing protein 0.0109 0.0326 0.033
Loa Loa (eye worm) TK/FER protein kinase 0.0081 0.0173 0.0173
Trichomonas vaginalis CAMK family protein kinase 0.0286 0.1313 0.8886
Echinococcus multilocularis protein kinase c iota type 0.031 0.1446 0.1494
Loa Loa (eye worm) hypothetical protein 0.0256 0.1147 0.1147
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0286 0.1313 0.1356
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Onchocerca volvulus 0.0504 0.2524 0.261
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Brugia malayi Protein kinase domain containing protein 0.0195 0.0808 0.0817
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0389 0.1887 0.1887
Giardia lamblia Aurora kinase 0.0153 0.0572 0.4316
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0128 0.0434 0.0441
Onchocerca volvulus Terribly reduced optic lobes homolog 0.0196 0.0809 0.0833
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0251 0.0255
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0286 0.1313 0.1356
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0105 0.0307 0.0312
Echinococcus granulosus epidermal growth factor receptor 0.0338 0.1602 0.1655
Echinococcus granulosus hypothetical protein 0.0129 0.0439 0.045
Leishmania major protein kinase, putative 0.0075 0.0136 0.0132
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0171 0.0675 0.0694
Brugia malayi SRC-1 0.0171 0.0675 0.0682
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0084 0.0188 0.0188
Brugia malayi casein kinase I 0.0114 0.0353 0.0357
Loa Loa (eye worm) TK/FER protein kinase 0.0405 0.1975 0.1975
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0127 0.0428 0.0439
Loa Loa (eye worm) hypothetical protein 0.0067 0.0093 0.0093
Loa Loa (eye worm) calcium binding EGF domain-containing protein 0.0196 0.0809 0.0809
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0251 0.0255
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0132 0.0457 0.0468
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.051 0.0524
Echinococcus granulosus delta-like protein 1 0.014 0.0502 0.0515
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0552 0.2791 0.2823
Echinococcus multilocularis transmembrane protease serine 3 0.0504 0.2524 0.261
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0254 0.1133 0.1169
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0141 0.0141
Echinococcus granulosus epidermal growth factor receptor 0.0487 0.2427 0.2509
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0105 0.0307 0.031
Trichomonas vaginalis STE family protein kinase 0.0088 0.021 0.1374
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0533 0.3572
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.027 0.1222 0.1222
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0177 0.0705 0.0726
Entamoeba histolytica protein kinase, putative 0.0073 0.0128 0.0624
Trichomonas vaginalis CAMK family protein kinase 0.0286 0.1313 0.8886
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0405 0.1975 0.2042
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0173 0.0682 0.0702
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0419 0.205 0.2119
Toxoplasma gondii hypothetical protein 0.0282 0.129 0.1328
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Echinococcus multilocularis raf serine:threonine protein kinase 0.0087 0.0204 0.0206
Echinococcus granulosus neural cadherin 0.014 0.0502 0.0515
Plasmodium falciparum serine/threonine protein kinase KIN 0.0093 0.0239 0.0238
Echinococcus granulosus basement membrane specific heparan sulfate 0.0211 0.0895 0.0922
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.008 0.0166 0.0166
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0073 0.0128 0.0128
Schistosoma mansoni tyrosine kinase 0.0422 0.2067 0.2137
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0129 0.044 0.0447
Trichomonas vaginalis CMGC family protein kinase 0.0087 0.0205 0.1336
Echinococcus granulosus tyrosine protein kinase Srms 0.0517 0.2595 0.2684
Entamoeba histolytica protein kinase , putative 0.0153 0.0572 0.287
Toxoplasma gondii calcium binding egf domain-containing protein 0.0357 0.1704 0.1758
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0309 0.144 0.144
Echinococcus multilocularis casein kinase I delta 0.0114 0.0353 0.0361
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0105 0.0307 0.0312
Loa Loa (eye worm) hypothetical protein 0.0095 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0075 0.0141 0.0141
Echinococcus multilocularis 0.0136 0.0478 0.049
Onchocerca volvulus 0.0196 0.0809 0.0833
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0211 0.0895 0.0922
Onchocerca volvulus 0.0196 0.0809 0.0833
Onchocerca volvulus 0.0196 0.0809 0.0833
Echinococcus multilocularis serine threonine protein kinase 0.0221 0.0948 0.0978
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0104 0.0302 0.0304
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0084 0.0189 0.0187
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Echinococcus multilocularis tissue type plasminogen activator 0.1787 0.9655 1
Brugia malayi phosphoinositide-dependent protein kinase I 0.0084 0.0191 0.0194
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0196 0.0811 0.0821
Giardia lamblia High cysteine protein 0.014 0.0502 0.3782
Loa Loa (eye worm) hypothetical protein 0.0153 0.0571 0.0571
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Loa Loa (eye worm) AGC/PKN protein kinase 0.0316 0.1476 0.1476
Trypanosoma cruzi hypothetical protein, conserved 0.1787 0.9655 1
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1004 0.5305 0.5305
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Entamoeba histolytica casein kinase 1, putative 0.0114 0.0353 0.1762
Echinococcus granulosus Glutaredoxin protein 5 0.0132 0.0457 0.0468
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0082 0.008
Loa Loa (eye worm) PAN domain-containing protein 0.0282 0.129 0.129
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.2542 0.2629
Schistosoma mansoni tyrosine kinase 0.0296 0.1369 0.1413
Schistosoma mansoni cell adhesion molecule 0.0052 0.0013 0.0008
Brugia malayi Tyrosine-protein kinase abl-1 0.0109 0.0326 0.033
Brugia malayi Immunoglobulin I-set domain containing protein 0.0274 0.1245 0.1259
Trypanosoma brucei SNF1-related protein kinases, putative 0.0093 0.0239 0.1566
Schistosoma mansoni kinase 0.0306 0.1423 0.1469
Brugia malayi Serine/threonine-protein kinase SULU 0.0235 0.1028 0.1039
Onchocerca volvulus 0.014 0.0502 0.0515
Echinococcus multilocularis snurportin 1 0.027 0.1222 0.1261
Loa Loa (eye worm) AUR protein kinase 0.0153 0.0572 0.0572
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0211 0.0895 0.0922
Trichomonas vaginalis CAMK family protein kinase 0.012 0.0391 0.2605
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0818
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0168 0.0653 0.0653
Loa Loa (eye worm) hypothetical protein 0.0068 0.0102 0.0102
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0132 0.0457 0.0465
Brugia malayi Protein kinase domain containing protein 0.0081 0.0173 0.0175
Onchocerca volvulus 0.0196 0.0809 0.0833
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0088 0.021 0.0209
Toxoplasma gondii EGF family domain-containing protein 0.014 0.0502 0.0511
Echinococcus multilocularis fibrillin 1 0.0357 0.1704 0.1761
Schistosoma mansoni hypothetical protein 0.0132 0.0457 0.0468
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0504 0.2524 0.261
Echinococcus multilocularis NCK adaptor protein 0.0069 0.0105 0.0103
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0173 0.0682 0.0702
Brugia malayi Doublecortin family protein 0.0159 0.0604 0.061
Echinococcus granulosus casein kinase I alpha 0.0114 0.0353 0.0361
Echinococcus granulosus tyrosine protein kinase Src42A 0.0104 0.03 0.0305
Brugia malayi STE20-like kinase MST 0.0272 0.1233 0.1247
Onchocerca volvulus 0.0135 0.0472 0.0484
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0173 0.0682 0.0682
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0489 0.2439 0.2439
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0152 0.0567 0.0583
Brugia malayi EGF-like domain containing protein 0.014 0.0502 0.0508
Plasmodium falciparum protein kinase 5 0.0124 0.0413 0.0419
Echinococcus multilocularis fibropellin Ia 0.014 0.0502 0.0515
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0228 0.0991 0.1022
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0302 0.1999
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0061 0.0061 0.0359
Brugia malayi Trypsin-like protease protein 5 0.0504 0.2524 0.2553
Brugia malayi Protein kinase domain containing protein 0.0316 0.1477 0.1494
Brugia malayi Variant SH3 domain containing protein 0.0067 0.0093 0.0094
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0353 0.0361
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0152 0.0568 0.0583
Brugia malayi EGF-like domain containing protein 0.014 0.0502 0.0508
Trypanosoma brucei casein kinase I, isoform 2 0.0114 0.0353 0.2345
Schistosoma mansoni hypothetical protein 0.1787 0.9655 1
Brugia malayi Protein kinase domain containing protein 0.0084 0.0191 0.0194
Echinococcus granulosus serine threonine protein kinase nrc 0.0165 0.0638 0.0656
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0265 0.1194 0.8071
Giardia lamblia Kinase, AGC PKA 0.0165 0.0638 0.4824
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0286 0.1313 0.1352
Brugia malayi protein kinase C3,putative 0.0166 0.0644 0.0652
Echinococcus multilocularis nervana 2 0.0132 0.0457 0.0468
Echinococcus multilocularis neurogenic locus notch protein 4 0.014 0.0502 0.0515
Loa Loa (eye worm) hypothetical protein 0.0119 0.0386 0.0386
Brugia malayi Protein kinase domain containing protein 0.0119 0.0385 0.039
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0251 0.0254
Loa Loa (eye worm) hypothetical protein 0.0081 0.0173 0.0173
Brugia malayi MAP kinase sur-1 0.0087 0.0205 0.0207
Brugia malayi CUB domain containing protein 0.0132 0.0457 0.0462
Onchocerca volvulus 0.0282 0.129 0.1331
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0171 0.0675 0.0691
Schistosoma mansoni adapter molecule crk 0.0067 0.0093 0.0091
Echinococcus granulosus ephrin type A receptor 4 A 0.011 0.0336 0.0343
Echinococcus granulosus serine:threonine protein kinase 0.0119 0.0385 0.0394
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Onchocerca volvulus 0.0204 0.0856 0.0881
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0504 0.2524 0.261
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0104 0.0302 0.0302
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0075 0.0141 0.0141
Leishmania major protein kinase A catalytic subunit isoform 1 0.0075 0.0141 0.0137
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0084 0.0188 0.0189
Schistosoma mansoni hypothetical protein 0.014 0.0502 0.0515
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0374 0.1802 0.1823
Brugia malayi hypothetical protein 0.0077 0.015 0.0152
Trichomonas vaginalis AGC family protein kinase 0.0316 0.1477 1
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0093 0.0239 0.0238
Loa Loa (eye worm) hypothetical protein 0.0092 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0193 0.0795 0.0795
Echinococcus granulosus tyrosine protein kinase ABL1 0.0081 0.0173 0.0174
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0162 0.062 0.062
Schistosoma mansoni growth factor receptor-bound protein 0.0069 0.0105 0.0103
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0533 0.3572
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0504 0.2524 0.2553
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Echinococcus multilocularis neurogenic locus notch protein 0.014 0.0502 0.0515
Entamoeba histolytica serine/threonine protein kinase, putative 0.0052 0.0009 0.0019
Toxoplasma gondii AGC kinase 0.0075 0.0141 0.0137
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0161 0.0617 0.0617
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0124 0.0413 0.0413
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0211 0.0895 0.0922
Loa Loa (eye worm) hypothetical protein 0.0132 0.0457 0.0457
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0132 0.0457 0.0468
Loa Loa (eye worm) TK/FER protein kinase 0.0081 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0095 0.0252 0.0252
Entamoeba histolytica protein kinase domain containing protein 0.0075 0.0136 0.0666
Schistosoma mansoni notch 0.014 0.0502 0.0515
Chlamydia trachomatis recombinase RecA 0.0095 0.0248 0.5
Echinococcus granulosus nervana 2 0.0132 0.0457 0.0468
Schistosoma mansoni hypothetical protein 0.0504 0.2524 0.261
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0081 0.0173 0.0174
Loa Loa (eye worm) DOMON domain-containing protein 0.1074 0.5691 0.5691
Brugia malayi Trypsin family protein 0.1294 0.6913 0.6991
Echinococcus multilocularis protein tyrosine kinase 0.0313 0.1459 0.1507
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Echinococcus multilocularis neural cadherin 0.014 0.0502 0.0515
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0128 0.0434 0.0434
Brugia malayi Protein kinase domain containing protein 0.0064 0.0075 0.0076
Giardia lamblia Kinase, NEK 0.0143 0.0516 0.3891
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0082 0.008
Giardia lamblia Kinase, CMGC CDK 0.0124 0.0413 0.3101
Echinococcus granulosus 5'partial|Low density lipoprotein receptor class A cysteine rich 0.0196 0.0809 0.0833
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0171 0.0675 0.0694
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0073 0.0128 0.0128
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0075 0.0141 0.0902
Onchocerca volvulus 0.0081 0.0173 0.0173
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0249 0.1104 0.1139
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0054 0.0025 0.0109
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0075 0.0141 0.0143
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0235 0.1028 0.1028
Entamoeba histolytica protein kinase, putative 0.0072 0.0121 0.0585
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0076 0.0146 0.0146
Brugia malayi serine/threonine-protein kinase 6 0.0153 0.0572 0.0578
Entamoeba histolytica protein kinase, putative 0.0142 0.051 0.2559
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Loa Loa (eye worm) hypothetical protein 0.0282 0.129 0.129
Loa Loa (eye worm) hypothetical protein 0.1214 0.6471 0.6471
Brugia malayi MH2 domain containing protein 0.012 0.0388 0.0392
Echinococcus granulosus Tolloid protein 1 0.0489 0.2439 0.2522
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Echinococcus granulosus dual specificity 0.0146 0.0533 0.0547
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Brugia malayi C1-like domain containing protein 0.023 0.1 0.1012
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0461 0.2286 0.2363
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0132 0.0457 0.0457
Brugia malayi Protein kinase domain containing protein 0.0199 0.0827 0.0836
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0509 0.0522
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0859 0.4494 0.4651
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0172 0.0681 0.0681
Schistosoma mansoni hypothetical protein 0.014 0.0502 0.0515
Loa Loa (eye worm) hypothetical protein 0.0196 0.0809 0.0809
Brugia malayi Kringle domain containing protein 0.1787 0.9655 0.9764
Brugia malayi Cam kinase protein 1 0.0105 0.0307 0.031
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Toxoplasma gondii histone kinase SNF1, putative 0.0093 0.0239 0.0238
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0132 0.0457 0.0468
Plasmodium vivax cysteine repeat modular protein 1, putative 0.1787 0.9655 1
Echinococcus granulosus roundabout 2 0.0052 0.0013 0.0008
Schistosoma mansoni protein kinase 0.0161 0.0617 0.0635
Schistosoma mansoni septate junction protein 0.014 0.0502 0.0515
Schistosoma mansoni hypothetical protein 0.0132 0.0457 0.0468
Trichomonas vaginalis AGC family protein kinase 0.0205 0.0864 0.5822
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0413 0.0423
Echinococcus granulosus protein kinase C gamma type 0.0221 0.0948 0.0978
Echinococcus granulosus neuropilin nrp and tolloid tll 0.0132 0.0457 0.0468
Schistosoma mansoni tyrosine kinase 0.027 0.1224 0.1263
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0141 0.0141
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Loa Loa (eye worm) zinc metalloproteinase toh-2 0.0132 0.0457 0.0457
Echinococcus granulosus casein kinase ii subunit alpha 0.0104 0.0302 0.0308
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Brugia malayi Protein kinase domain containing protein 0.0374 0.1802 0.1823
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0105 0.0307 0.2029
Entamoeba histolytica protein kinase, putative 0.0128 0.0434 0.217
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0084 0.0191 0.0191
Brugia malayi P38 map kinase family protein 2 0.0168 0.0653 0.066
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0356 0.1701 0.172
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0075 0.0141 0.0137
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.008 0.0166 0.0166
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0472 0.3155
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0114 0.0353 0.0353
Echinococcus multilocularis tyrosine protein kinase Srms 0.0144 0.0521 0.0535
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0302 0.1999
Echinococcus granulosus dual specificity 0.0128 0.0434 0.0444
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1622 0.8735 0.9046
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Echinococcus multilocularis N chimaerin 0.0084 0.0188 0.0189
Echinococcus granulosus casein kinase i 0.0114 0.0353 0.0361
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0165 0.0638 0.0656
Loa Loa (eye worm) hypothetical protein 0.0504 0.2524 0.2524
Schistosoma mansoni hypothetical protein 0.0196 0.0809 0.0833
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0052 0.0013 0.0008
Brugia malayi EGF-like domain containing protein 0.014 0.0502 0.0508
Loa Loa (eye worm) hypothetical protein 0.0119 0.0386 0.0386
Leishmania major protein kinase A catalytic subunit isoform 2 0.0075 0.0141 0.0137
Brugia malayi basement membrane proteoglycan precursor 0.0211 0.0895 0.0905
Giardia lamblia Kinase, NEK 0.0143 0.0516 0.3891
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Trypanosoma cruzi polo-like protein kinase, putative 0.0286 0.1313 0.1352
Loa Loa (eye worm) hypothetical protein 0.0132 0.0457 0.0457
Entamoeba histolytica protein kinase, putative 0.009 0.0223 0.1104
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0153 0.0572 0.0587
Loa Loa (eye worm) notch protein 0.014 0.0502 0.0502
Echinococcus granulosus aurora kinase A 0.0153 0.0572 0.0587
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0075 0.0141 0.0902
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Schistosoma mansoni titin 0.0069 0.0108 0.0107
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0075 0.0141 0.0137
Schistosoma mansoni protein kinase 0.0461 0.2286 0.2363
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.1205 0.1244
Brugia malayi Calcium binding EGF domain containing protein 0.014 0.0502 0.0508
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Echinococcus granulosus protein kinase shaggy 0.0135 0.0472 0.0484
Echinococcus granulosus casein kinase I alpha 0.0114 0.0353 0.0361
Echinococcus granulosus tyrosine kinase 0.0144 0.0521 0.0535
Schistosoma mansoni serine/threonine protein kinase 0.0286 0.1313 0.1356
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0105 0.0307 0.0312
Plasmodium vivax tyrosine kinase-like protein, putative 0.0084 0.0189 0.0187
Echinococcus granulosus histone acetyltransferase KAT2B 0.0124 0.0408 0.0418
Toxoplasma gondii calcium binding egf domain-containing protein 0.0357 0.1704 0.1758
Leishmania major protein kinase, putative 0.0162 0.062 0.0634
Onchocerca volvulus 0.0334 0.1577 0.1629
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0108 0.0109
Loa Loa (eye worm) thyroid receptor interactor 0.0109 0.0326 0.0326
Brugia malayi Stress-activated protein kinase jnk-1 0.028 0.1278 0.1292
Plasmodium vivax protein kinase Crk2 0.0124 0.0413 0.0419
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0166 0.0167
Giardia lamblia Kinase, STE STE20 0.0088 0.021 0.1546
Onchocerca volvulus 0.014 0.0502 0.0515
Loa Loa (eye worm) TK/ABL protein kinase 0.0081 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0504 0.2524 0.2524
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0087 0.0205 0.0203
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0374 0.1802 0.1802
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0338 0.1602 0.1655
Loa Loa (eye worm) hypothetical protein 0.0504 0.2524 0.2524
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0552 0.2791 0.2791
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0104 0.03 0.0305
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0439 0.216 0.2233
Schistosoma mansoni growth factor receptor-bound protein 0.0067 0.0093 0.0091
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0267 0.1205 0.1244
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0007 0.0007
Echinococcus multilocularis c Jun NH2 terminal kinase 0.028 0.1278 0.1319
Echinococcus granulosus mitogen activated protein kinase 3 0.0087 0.0205 0.0207
Loa Loa (eye worm) hypothetical protein 0.0504 0.2524 0.2524
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Onchocerca volvulus 0.1787 0.9655 1
Loa Loa (eye worm) hypothetical protein 0.0132 0.0457 0.0457
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Giardia lamblia Kinase, CK1 Casein kinase 0.0114 0.0353 0.2639
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0263 0.1183 0.1183
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0405 0.1975 0.2042
Brugia malayi p70 ribosomal S6 kinase beta 0.0309 0.144 0.1456
Echinococcus multilocularis microtubule associated protein 2 0.0605 0.3085 0.3191
Brugia malayi CUB domain containing protein 0.0328 0.1544 0.1561
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.0178 0.0875
Echinococcus granulosus slit 2 protein 0.0172 0.0675 0.0694
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0353 0.2345
Echinococcus granulosus rho-associated protein kinase 1 0.0345 0.1639 0.1694
Toxoplasma gondii AGC kinase 0.0075 0.0141 0.0137
Echinococcus granulosus glycoprotein Antigen 5 0.0504 0.2524 0.261
Echinococcus granulosus serine:threonine protein kinase 0.0119 0.0385 0.0394
Echinococcus multilocularis tyrosine protein kinase Blk 0.0144 0.0521 0.0535
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1294 0.6913 0.7158
Entamoeba histolytica protein kinase, putative 0.0131 0.0449 0.2247
Onchocerca volvulus Neurogenic locus notch homolog 0.014 0.0502 0.0515
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0504 0.2524 0.261
Echinococcus granulosus protein kinase c iota type 0.031 0.1446 0.1494
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Echinococcus multilocularis serine:threonine protein kinase N2 0.0139 0.0492 0.0505
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0093 0.0239 0.0238
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0061 0.0061 0.0359
Mycobacterium leprae Conserved hypothetical protein 0.0555 0.2807 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0051 0.0007 0.0007
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0075 0.0136 0.0132
Schistosoma mansoni protein kinase 0.0461 0.2286 0.2363
Brugia malayi cell division control protein 2 homolog 0.0124 0.0413 0.0418
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0054 0.0025 0.0109
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.023 0.1 0.1012
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0127 0.0428 0.0439
Trichomonas vaginalis CAMK family protein kinase 0.0286 0.1313 0.8886
Brugia malayi Protein kinase domain 0.0131 0.0449 0.0454
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0239 0.0242
Entamoeba histolytica protein kinase, putative 0.0105 0.0304 0.1512
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0171 0.0675 0.0694
Echinococcus granulosus roundabout 2 0.0052 0.0013 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0533 0.3572
Onchocerca volvulus 0.1074 0.5691 0.5892
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0084 0.0191 0.0193
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0472 0.2364
Toxoplasma gondii microneme protein MIC17C 0.0282 0.129 0.1328
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0165 0.0638 0.0652
Echinococcus multilocularis mitogen activated protein kinase 0.0087 0.0205 0.0207
Onchocerca volvulus Neurogenic locus notch protein homolog 0.014 0.0502 0.0515
Trypanosoma cruzi casein kinase, putative 0.0114 0.0353 0.0357
Onchocerca volvulus Serine\/threonine kinase homolog 0.0173 0.0682 0.0702
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0093 0.0239 0.0238
Entamoeba histolytica protein kinase, putative 0.0316 0.1477 0.7451
Echinococcus multilocularis Immunoglobulin 0.006 0.0057 0.0054
Loa Loa (eye worm) PAN domain-containing protein 0.0282 0.129 0.129
Trichomonas vaginalis CAMK family protein kinase 0.0286 0.1313 0.8886
Echinococcus granulosus dual specificity protein kinase clk2 0.0162 0.062 0.0638
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0093 0.0239 0.1566
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0114 0.0353 0.0353
Loa Loa (eye worm) hypothetical protein 0.0196 0.0809 0.0809
Plasmodium falciparum cGMP-dependent protein kinase 0.0141 0.0507 0.0517
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0419 0.205 0.2119
Giardia lamblia Kinase, CMGC CDK 0.0124 0.0413 0.3101
Echinococcus multilocularis serine:threonine protein kinase 3 0.0272 0.1233 0.1273
Echinococcus multilocularis Immunoglobulin 0.006 0.0057 0.0054
Trypanosoma brucei polo-like protein kinase 0.0286 0.1313 0.8886
Echinococcus multilocularis tyrosine protein kinase Abl 0.0109 0.0326 0.0333
Toxoplasma gondii casein kinase I 0.0114 0.0353 0.0357
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0013 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0572 0.0587
Echinococcus multilocularis serine:threonine protein kinase N2 0.0177 0.0705 0.0726
Echinococcus granulosus c src tyrosine kinase 0.0109 0.0326 0.0333
Schistosoma mansoni protein kinase 0.0461 0.2286 0.2363
Onchocerca volvulus 0.0148 0.0547 0.0561
Loa Loa (eye worm) CAMK/PKD protein kinase 0.023 0.1 0.1
Echinococcus granulosus NDR protein kinase 0.0177 0.0705 0.0726
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Mycobacterium ulcerans hypothetical protein 0.0139 0.0497 0.1096
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0142 0.051 0.052
Brugia malayi Protein kinase domain containing protein 0.0204 0.0853 0.0863
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.09 0.0928
Loa Loa (eye worm) TK/FER protein kinase 0.0081 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Brugia malayi Protein kinase domain containing protein 0.1829 0.9888 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0075 0.0141 0.0141
Schistosoma mansoni hypothetical protein 0.0109 0.0327 0.0334
Plasmodium falciparum serine/threonine protein kinase, putative 0.0153 0.0572 0.0584
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0124 0.0413 0.0419
Trichomonas vaginalis AGC family protein kinase 0.0153 0.0572 0.3836
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0504 0.2524 0.261
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.0239 0.1182
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0214 0.0911 0.0939
Schistosoma mansoni nephrin 0.0097 0.0262 0.0266
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0087 0.0205 0.0203
Echinococcus multilocularis 0.0129 0.0439 0.045
Echinococcus granulosus dual specificity 0.0146 0.0533 0.0547
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0146 0.0533 0.0539
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0199 0.0827 0.0827
Loa Loa (eye worm) acetyltransferase 0.0127 0.0428 0.0428
Brugia malayi Protein kinase domain containing protein 0.0162 0.062 0.0627
Echinococcus multilocularis Mastin 0.0504 0.2524 0.261
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0504 0.2524 0.261
Echinococcus granulosus Immunoglobulin 0.006 0.0057 0.0054
Echinococcus granulosus titin 0.0069 0.0108 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Brugia malayi Protein kinase domain containing protein 0.0128 0.0434 0.0439
Brugia malayi Protein kinase domain containing protein 0.0142 0.051 0.0516
Echinococcus multilocularis neurogenic locus protein delta 0.014 0.0502 0.0515
Loa Loa (eye worm) PAN domain-containing protein 0.0282 0.129 0.129
Trypanosoma cruzi casein kinase II, putative 0.0104 0.0302 0.0304
Echinococcus multilocularis protein kinase c epsilon type 0.0223 0.0961 0.0991
Onchocerca volvulus 0.0216 0.0921 0.0948
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0013 0.0013
Echinococcus granulosus raf serine:threonine protein kinase 0.0087 0.0204 0.0206
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0052 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.006 0.0057 0.0057
Echinococcus multilocularis CUB 0.0132 0.0457 0.0468
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0168 0.0653 0.0668
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0171 0.0675 0.0694
Echinococcus multilocularis cubilin 0.0132 0.0457 0.0468
Onchocerca volvulus 0.0081 0.0172 0.0172
Plasmodium vivax casein kinase 1, putative 0.0114 0.0353 0.0357
Onchocerca volvulus 0.0282 0.129 0.1331
Echinococcus granulosus protein jagged 1 0.014 0.0502 0.0515
Echinococcus granulosus neurogenic locus protein delta 0.014 0.0502 0.0515
Echinococcus multilocularis ephrin type A receptor 4 A 0.011 0.0336 0.0343
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0162 0.062 0.0634
Brugia malayi Protein kinase domain containing protein 0.0124 0.0413 0.0418
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0075 0.0141 0.0141
Loa Loa (eye worm) TK/FER protein kinase 0.0081 0.0173 0.0173
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0168 0.0653 0.0668
Entamoeba histolytica protein kinase 2, putative 0.0165 0.0638 0.3205
Onchocerca volvulus 0.0153 0.0571 0.0586
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0267 0.1205 0.1244
Schistosoma mansoni hypothetical protein 0.014 0.0502 0.0515
Echinococcus multilocularis serine:threonine protein kinase 0.0119 0.0385 0.0394
Entamoeba histolytica protein kinase, putative 0.0128 0.0434 0.217
Loa Loa (eye worm) hypothetical protein 0.0434 0.2132 0.2132
Brugia malayi hypothetical protein 0.0119 0.0386 0.039
Giardia lamblia Kinase, CMGC CK2 0.0104 0.0302 0.225
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0119 0.0386 0.0391
Trypanosoma brucei protein kinase, putative 0.0075 0.0136 0.087
Trichomonas vaginalis CAMK family protein kinase 0.0132 0.0458 0.3062
Echinococcus granulosus serine:threonine kinase SAD 1 0.0093 0.0239 0.0242
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Loa Loa (eye worm) hypothetical protein 0.0196 0.0809 0.0809
Entamoeba histolytica PH domain containing protein kinase, putative 0.0171 0.0675 0.3391
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Echinococcus granulosus calcium dependent protein kinase 0.0073 0.0125 0.0125
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0075 0.0141 0.0141
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0132 0.0457 0.3053
Entamoeba histolytica cell division protein kinase 2, putative 0.0124 0.0413 0.2067
Trichomonas vaginalis AGC family protein kinase 0.0177 0.0705 0.4744
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0168 0.0653 0.4388
Trypanosoma cruzi polo-like protein kinase, putative 0.0286 0.1313 0.1352
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1557 0.8377 1
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0105 0.0307 0.0309
Onchocerca volvulus 0.014 0.0502 0.0515
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0353 0.0361
Loa Loa (eye worm) CAMK protein kinase 0.0069 0.0108 0.0108
Echinococcus multilocularis serine:threonine protein kinase 0.0119 0.0385 0.0394
Loa Loa (eye worm) hypothetical protein 0.0204 0.0856 0.0856
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0119 0.0386 0.0395
Plasmodium falciparum protein kinase, putative 0.0075 0.0136 0.0132
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0146 0.0533 0.0544
Loa Loa (eye worm) AGC/NDR protein kinase 0.0177 0.0705 0.0705
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0075 0.0141 0.0137
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.0178 0.0875
Loa Loa (eye worm) TK protein kinase 0.0144 0.0521 0.0521
Leishmania major hypothetical protein, conserved 0.1787 0.9655 1
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0251 0.0255
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0124 0.0413 0.0419
Entamoeba histolytica protein kinase, putative 0.0153 0.0572 0.287
Brugia malayi CUB domain containing protein 0.0132 0.0457 0.0462
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0239 0.0242
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0123 0.0403 0.0408
Toxoplasma gondii PAN domain-containing protein 0.0282 0.129 0.1328
Schistosoma mansoni hypothetical protein 0.014 0.0502 0.0515
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0143 0.0516 0.0526
Schistosoma mansoni tyrosine kinase 0.0309 0.1441 0.1488
Toxoplasma gondii microneme protein MIC17B 0.0282 0.129 0.1328
Onchocerca volvulus 0.0132 0.0457 0.0468
Loa Loa (eye worm) hypothetical protein 0.0077 0.015 0.015
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0052 0.0013 0.0008
Echinococcus multilocularis calcium dependent protein kinase 0.0073 0.0125 0.0125
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.012 0.0391 0.04
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0374 0.1802 0.1862
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0054 0.0025 0.0109
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0119 0.0386 0.2569
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0069 0.0108 0.0108
Onchocerca volvulus Arrow homolog 0.0552 0.2791 0.2887
Echinococcus granulosus activin receptor type 0.0075 0.0136 0.0136
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0809
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0353 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0239 0.0242
Echinococcus multilocularis cubilin 0.0132 0.0457 0.0468
Schistosoma mansoni vam6/vps39 related 0.0119 0.0386 0.0395
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Echinococcus multilocularis roundabout 2 0.0052 0.0013 0.0008
Toxoplasma gondii PAN domain-containing protein 0.0282 0.129 0.1328
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Schistosoma mansoni tyrosine kinase 0.0109 0.0326 0.0333
Echinococcus granulosus enteropeptidase 0.0504 0.2524 0.261
Loa Loa (eye worm) hypothetical protein 0.0132 0.0457 0.0457
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0072 0.0121 0.0585
Echinococcus multilocularis dual specificity 0.0146 0.0533 0.0547
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0165 0.0638 0.0656
Loa Loa (eye worm) hypothetical protein 0.0273 0.1237 0.1237
Brugia malayi EGF-like domain containing protein 0.014 0.0502 0.0508
Loa Loa (eye worm) AUR protein kinase 0.0153 0.0572 0.0572
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0135 0.0472 0.0472
Echinococcus granulosus microtubule associated protein 2 0.0605 0.3085 0.3191
Entamoeba histolytica casein kinase, putative 0.0114 0.0353 0.1762
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0472 0.3155
Entamoeba histolytica protein kinase, putative 0.0105 0.0307 0.1527
Echinococcus granulosus serine:threonine protein kinase 3 0.0272 0.1233 0.1273
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0249 0.1104 0.1139
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Onchocerca volvulus 0.0081 0.0173 0.0173
Schistosoma mansoni tyrosine kinase 0.0313 0.1459 0.1507
Loa Loa (eye worm) CUB domain-containing protein 0.0132 0.0457 0.0457
Loa Loa (eye worm) AUR protein kinase 0.0153 0.0572 0.0572
Entamoeba histolytica protein kinase, putative 0.009 0.0223 0.1104
Echinococcus granulosus tar DNA binding protein 0.0065 0.0082 0.008
Loa Loa (eye worm) hypothetical protein 0.0132 0.0457 0.0457
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0152 0.0567 0.0583
Echinococcus multilocularis serine:threonine protein kinase N2 0.0316 0.1476 0.1524
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0388 0.0388
Loa Loa (eye worm) TK/EGFR protein kinase 0.0487 0.2427 0.2427
Loa Loa (eye worm) hypothetical protein 0.1294 0.6913 0.6913
Trichomonas vaginalis CAMK family protein kinase 0.0119 0.0385 0.2566
Entamoeba histolytica protein kinase, putative 0.0153 0.0572 0.287
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0093 0.0239 0.0238
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Echinococcus multilocularis dual specificity 0.0128 0.0434 0.0444
Echinococcus granulosus twitchin 0.0113 0.035 0.0358
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0093 0.0239 0.0238
Echinococcus granulosus cyclin dependent kinase 5 0.0124 0.0413 0.0423
Loa Loa (eye worm) hypothetical protein 0.0282 0.129 0.129
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0135 0.0472 0.0484
Echinococcus granulosus neurogenic locus notch protein 0.014 0.0502 0.0515
Brugia malayi RhoGAP domain containing protein 0.0084 0.0188 0.019
Loa Loa (eye worm) hypothetical protein 0.0196 0.0809 0.0809
Trichomonas vaginalis STE family protein kinase 0.0131 0.0449 0.2998
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0085 0.0194 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0204 0.0206
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0818
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0087 0.0205 0.0203
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0171 0.0675 0.0694
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0051 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0307 0.0312
Trypanosoma brucei protein kinase, putative 0.0135 0.0472 0.3155
Brugia malayi Cadherin domain containing protein 0.014 0.0502 0.0508
Schistosoma mansoni serine/threonine protein kinase 0.028 0.1278 0.1319
Echinococcus granulosus basement membrane specific heparan sulfate 0.0196 0.0809 0.0833
Echinococcus granulosus fibroblast growth factor receptor 4 0.0254 0.1133 0.1169
Brugia malayi SH2 domain containing protein 0.0405 0.1975 0.1998
Schistosoma mansoni notch 0.014 0.0502 0.0515
Brugia malayi Kinase associated domain 1 family protein 0.0109 0.0327 0.0331
Loa Loa (eye worm) hypothetical protein 0.0211 0.0895 0.0895
Giardia lamblia Kinase, CMGC GSK 0.0135 0.0472 0.355
Brugia malayi EGF-like domain containing protein 0.014 0.0502 0.0508
Echinococcus granulosus cyclin dependent kinase 0.0124 0.0413 0.0423
Loa Loa (eye worm) hypothetical protein 0.0148 0.0547 0.0547
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0087 0.0205 0.0203
Loa Loa (eye worm) hypothetical protein 0.0363 0.1742 0.1742
Echinococcus granulosus Low density lipoprotein receptor class A cysteine rich 0.0196 0.0809 0.0833
Loa Loa (eye worm) TK/INSR protein kinase 0.0422 0.2067 0.2067
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0256 0.1144 0.1181
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0434 0.0444
Loa Loa (eye worm) hypothetical protein 0.0132 0.0457 0.0457
Loa Loa (eye worm) hypothetical protein 0.0105 0.0307 0.0307
Echinococcus granulosus neuroglian 0.0052 0.0013 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0302 0.1999
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0489 0.2439 0.2522
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.014 0.0502 0.0515
Brugia malayi acetyltransferase, GNAT family protein 0.0127 0.0428 0.0433
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.0911 0.0939
Entamoeba histolytica protein kinase domain containing protein 0.0214 0.0911 0.4589
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0231 0.1007 0.1038
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0087 0.0205 0.0203
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0214 0.0911 0.0911
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0533 0.3572
Echinococcus multilocularis cyclin dependent kinase 0.0124 0.0413 0.0423
Schistosoma mansoni protein kinase 0.0104 0.0302 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0015 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0286 0.1313 0.8886
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0124 0.0413 0.0413
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0082 0.008
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0124 0.0413 0.0413
Echinococcus granulosus protein tyrosine kinase 0.0313 0.1459 0.1507
Trypanosoma cruzi aurora B kinase, putative 0.0153 0.0572 0.0584
Toxoplasma gondii aurora kinase 0.0153 0.0572 0.0584
Schistosoma mansoni tyrosine kinase 0.0254 0.1133 0.1169
Echinococcus granulosus low density lipoprotein receptor ldl 0.0211 0.0895 0.0922
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0452 0.2232 0.2232
Echinococcus granulosus serine:threonine protein kinase N2 0.0316 0.1476 0.1524
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0105 0.0307 0.0312
Leishmania major protein kinase, putative 0.0088 0.021 0.0209
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0185 0.0752 0.0752
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.008 0.0166 0.107
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0357 0.1704 0.1704
Schistosoma mansoni notch 0.014 0.0502 0.0515
Loa Loa (eye worm) hypothetical protein 0.0357 0.1704 0.1704
Onchocerca volvulus 0.1074 0.5691 0.5892
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0125 0.0418 0.2791
Loa Loa (eye worm) hypothetical protein 0.0196 0.0809 0.0809
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0248 0.11 0.1135
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0211 0.0895 0.0922
Echinococcus granulosus laminin 0.0357 0.1704 0.1761
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0196 0.0811 0.0836
Echinococcus granulosus cyclin dependent kinase 1 0.0124 0.0413 0.0423
Leishmania major protein kinase A catalytic subunit 0.0075 0.0141 0.0137
Brugia malayi Hr1 repeat family protein 0.0316 0.1476 0.1492
Brugia malayi P21-Rho-binding domain containing protein 0.0051 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0199 0.0827 0.5572
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0388 0.0388
Brugia malayi probable protein kinase 0.0281 0.1281 0.1296
Echinococcus multilocularis casein kinase ii subunit alpha 0.0104 0.0302 0.0308
Brugia malayi ephrin receptor 1 precursor 0.0074 0.0134 0.0136
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0307 0.2029
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0159 0.0604 0.0604
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0073 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Schistosoma mansoni serine/threonine-protein kinase 0.0171 0.0675 0.0694
Plasmodium falciparum casein kinase 2, alpha subunit 0.0104 0.0302 0.0304
Brugia malayi Trypsin family protein 0.0504 0.2524 0.2553
Echinococcus multilocularis myosin iiia 0.0088 0.021 0.0213
Giardia lamblia Kinase, AGC PKA 0.0075 0.0141 0.1015
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0131 0.0449 0.046
Echinococcus granulosus tyrosine kinase 0.0081 0.0173 0.0174
Leishmania major protein kinase, putative 0.0105 0.0307 0.0309
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.062 0.0638
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0076 0.0143 0.0143
Echinococcus granulosus c-Jun N-terminal kinases 0.028 0.1278 0.1319
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0177 0.0705 0.0726
Onchocerca volvulus 0.0282 0.129 0.1331
Echinococcus granulosus cubilin 0.0132 0.0457 0.0468
Entamoeba histolytica serine/threonine protein kinase, putative 0.0286 0.1313 0.6624
Schistosoma mansoni notch 0.014 0.0502 0.0515
Schistosoma mansoni nck2/grb4 0.0067 0.0093 0.0091
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0211 0.0895 0.0922
Leishmania major casein kinase II, putative 0.0104 0.0302 0.0304
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0636 0.3259 0.3372
Echinococcus multilocularis insulin receptor 0.0422 0.2067 0.2137
Toxoplasma gondii hypothetical protein 0.0282 0.129 0.1328
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0144 0.0521 0.0535
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0212 0.09 0.09
Brugia malayi hypothetical protein 0.006 0.0057 0.0058
Brugia malayi Trypsin family protein 0.0504 0.2524 0.2553
Echinococcus granulosus calcium activated potassium channel 0.0142 0.0509 0.0522
Brugia malayi WH1 domain containing protein 0.0051 0.0005 0.0005
Schistosoma mansoni cell adhesion molecule 0.0093 0.0236 0.024
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Loa Loa (eye worm) AGC/PKG protein kinase 0.0141 0.0507 0.0507
Brugia malayi Immunoglobulin I-set domain containing protein 0.0077 0.015 0.0152
Echinococcus granulosus tyrosine protein kinase Lyn 0.0204 0.0856 0.0882
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Onchocerca volvulus 0.1294 0.6913 0.7158
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0228 0.0991 0.1022
Loa Loa (eye worm) hypothetical protein 0.0119 0.0386 0.0386
Entamoeba histolytica protein kinase domain containing protein 0.0153 0.0572 0.287
Echinococcus multilocularis nervana 2 0.0132 0.0457 0.0468
Echinococcus granulosus myotubularin protein 13 0.0051 0.0007 0.0002
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0336 0.1588 0.1588
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0075 0.0141 0.0137
Loa Loa (eye worm) TK/FER protein kinase 0.0081 0.0173 0.0173
Schistosoma mansoni atypical protein kinase C 0.0317 0.1483 0.1531
Echinococcus multilocularis titin 0.0069 0.0108 0.0107
Loa Loa (eye worm) TK protein kinase 0.0105 0.0304 0.0304
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0143 0.0516 0.0526
Echinococcus granulosus cGMP dependent protein kinase 0.0141 0.0507 0.052
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0214 0.0911 0.0922
Onchocerca volvulus 0.014 0.0502 0.0515
Giardia lamblia Kinase, NEK 0.0143 0.0516 0.3891
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0105 0.0307 0.0309
Brugia malayi Muscle positioning protein 4 0.1214 0.6471 0.6545
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0196 0.0811 0.0836
Trypanosoma brucei rac serine-threonine kinase, putative 0.0316 0.1477 1
Echinococcus multilocularis aurora kinase A 0.0153 0.0572 0.0587
Echinococcus multilocularis calcium activated potassium channel 0.0142 0.0509 0.0522
Loa Loa (eye worm) hypothetical protein 0.0096 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0096 0.0255 0.0255
Trichomonas vaginalis CAMK family protein kinase 0.0286 0.1313 0.8886
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0082 0.008
Brugia malayi Protein kinase domain containing protein 0.0205 0.0859 0.0868
Echinococcus multilocularis protein jagged 2 0.014 0.0502 0.0515
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0131 0.0449 0.046
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0125 0.0418 0.0425
Echinococcus multilocularis serine:threonine protein kinase 38 0.0177 0.0705 0.0726
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0105 0.0307 0.0309
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0177 0.0705 0.0726
Echinococcus multilocularis twitchin 0.0053 0.0015 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0124 0.0413 0.2756
Loa Loa (eye worm) hypothetical protein 0.0051 0.0007 0.0007
Echinococcus granulosus neurogenic locus notch protein 0.014 0.0502 0.0515
Plasmodium vivax calcium-dependent protein kinase, putative 0.0105 0.0307 0.0309
Echinococcus multilocularis myotubularin protein 13 0.0051 0.0007 0.0002
Brugia malayi hypothetical protein 0.0132 0.0457 0.0462
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0165 0.0638 0.0652
Echinococcus granulosus growth factor receptor bound protein 2 0.0069 0.0105 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0392 0.0401
Schistosoma mansoni ephrin receptor 0.011 0.0336 0.0343
Schistosoma mansoni protein kinase 0.0281 0.1281 0.1323
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0302 0.1999
Toxoplasma gondii PAN domain-containing protein 0.0282 0.129 0.1328
Brugia malayi Lectin C-type domain containing protein 0.0132 0.0457 0.0462
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0144 0.0521 0.0535
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0013 0.0013
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0166 0.0645 0.4337
Echinococcus granulosus tyrosine protein kinase HCK 0.0105 0.0304 0.0309
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0135 0.0472 0.048
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.0457 0.3053
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0131 0.0449 0.046
Loa Loa (eye worm) hypothetical protein 0.0282 0.129 0.129
Trichomonas vaginalis STE family protein kinase 0.0131 0.0449 0.2998
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0533 0.3572
Entamoeba histolytica protein kinase, putative 0.0316 0.1477 0.7451
Schistosoma mansoni protein kinase 0.0241 0.106 0.1094
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0109 0.0326 0.0333
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0088 0.021 0.104
Trichomonas vaginalis AGC family protein kinase 0.0153 0.0572 0.3836
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0052 0.0013 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Echinococcus granulosus serine/threonine protein kinase 0.0171 0.0675 0.0694
Trichomonas vaginalis AGC family protein kinase 0.0153 0.0572 0.3836
Trichomonas vaginalis AGC family protein kinase 0.0316 0.1477 1
Schistosoma mansoni laminin gamma-3 chain 0.014 0.0502 0.0515
Plasmodium falciparum NIMA related kinase 1 0.0143 0.0516 0.0526
Brugia malayi Furin-like cysteine rich region family protein 0.0487 0.2427 0.2454
Echinococcus granulosus tyrosine protein kinase Src64B 0.0171 0.0675 0.0694
Schistosoma mansoni tyrosine kinase 0.0109 0.0326 0.0333
Toxoplasma gondii AGC kinase 0.0309 0.144 0.1484
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0153 0.0572 0.287
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0162 0.062 0.0634
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0533 0.0547
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0131 0.0449 0.046
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0124 0.0413 0.0423
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0419 0.205 0.205
Echinococcus multilocularis mitogen activated protein kinase 11 0.0168 0.0653 0.0671
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0212 0.09 0.0928
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.1476 0.1524
Trypanosoma cruzi cdc2-related kinase 1 0.0124 0.0413 0.0419
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0251 0.0251
Brugia malayi Protein kinase domain containing protein 0.0081 0.0173 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Onchocerca volvulus 0.0081 0.0173 0.0173
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0093 0.0239 0.0242
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0196 0.0809 0.0833
Brugia malayi serine/threonine-protein kinase PAK 7 0.0263 0.1183 0.1197
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0084 0.0188 0.0189
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0128 0.0434 0.2895
Onchocerca volvulus 0.0504 0.2524 0.261
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Loa Loa (eye worm) AGC/AKT protein kinase 0.0316 0.1477 0.1477
Brugia malayi EGF-like domain containing protein 0.014 0.0502 0.0508
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0135 0.0472 0.0472
Echinococcus granulosus Protein kinase C brain isozyme 0.0265 0.1197 0.1235
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0374 0.1802 0.1802
Brugia malayi EGF-like domain containing protein 0.0172 0.0675 0.0683
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.008 0.0166 0.0163
Echinococcus granulosus tyrosine protein kinase Src42A 0.0171 0.0675 0.0694
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0105 0.0307 0.0312
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0146 0.0533 0.3572
Loa Loa (eye worm) Notch2 0.014 0.0502 0.0502
Loa Loa (eye worm) hypothetical protein 0.0282 0.129 0.129
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0282 0.129 0.1328
Loa Loa (eye worm) hypothetical protein 0.0684 0.3526 0.3526
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.012 0.0391 0.04
Brugia malayi hypothetical protein 0.0081 0.0173 0.0175
Brugia malayi Casein kinase II, alpha chain 0.0104 0.0302 0.0306
Loa Loa (eye worm) hypothetical protein 0.006 0.0057 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Schistosoma mansoni protein kinase 0.0131 0.0449 0.046
Echinococcus multilocularis enteropeptidase 0.0504 0.2524 0.261
Onchocerca volvulus 0.0504 0.2524 0.261
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0705 0.0726
Schistosoma mansoni tyrosine kinase 0.0171 0.0675 0.0694
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0162 0.062 0.4166
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0162 0.062 0.0634
Plasmodium falciparum casein kinase 1 0.0114 0.0353 0.0357
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0141 0.0507 0.0517
Brugia malayi Egg laying defective protein 4 0.0141 0.0507 0.0513
Entamoeba histolytica hypothetical protein 0.0406 0.198 1
Trypanosoma cruzi casein kinase, putative 0.0114 0.0353 0.0357
Brugia malayi notch-like transmembrane receptor 0.014 0.0502 0.0508
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0818
Brugia malayi Protein kinase domain containing protein 0.0081 0.0173 0.0175
Echinococcus multilocularis rac serine:threonine kinase 0.0171 0.0675 0.0694
Entamoeba histolytica protein kinase, putative 0.0084 0.0186 0.0918
Giardia lamblia Kinase, STE STE20 0.0131 0.0449 0.3374
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0146 0.0533 0.0544
Onchocerca volvulus Tyrosine kinase homolog 0.0396 0.1922 0.1987
Schistosoma mansoni tyrosine kinase 0.0078 0.0153 0.0153
Schistosoma mansoni notch 0.014 0.0502 0.0515
Echinococcus granulosus roundabout 2 0.0113 0.0348 0.0355
Onchocerca volvulus 0.0081 0.0173 0.0173
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0461 0.2286 0.2363
Trypanosoma brucei Casein kinase II 0.0104 0.0302 0.1999
Schistosoma mansoni hypothetical protein 0.0504 0.2524 0.261
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0507 0.052
Echinococcus granulosus mitogen activated protein kinase 11 0.0168 0.0653 0.0671
Onchocerca volvulus 0.0282 0.129 0.1331
Schistosoma mansoni tyrosine kinase 0.0338 0.1602 0.1655
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0152 0.0568 0.0583
Schistosoma mansoni protein kinase 0.0241 0.106 0.1094
Entamoeba histolytica protein kinase, putative 0.0142 0.051 0.2559
Schistosoma mansoni ephrin receptor 0.0059 0.0048 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0119 0.0386 0.0395
Echinococcus multilocularis glycoprotein Antigen 5 0.0504 0.2524 0.261
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0204 0.0853 0.0853
Brugia malayi Protein kinase domain containing protein 0.0316 0.1477 0.1494
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0191 0.1245
Trichomonas vaginalis AGC family protein kinase 0.0316 0.1477 1
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0191 0.0193
Loa Loa (eye worm) hypothetical protein 0.0148 0.0547 0.0547
Echinococcus multilocularis expressed protein 0.0142 0.051 0.0524
Echinococcus multilocularis roundabout 2 0.0113 0.0348 0.0355
Onchocerca volvulus 0.0132 0.0457 0.0468
Echinococcus granulosus cGMP dependent protein kinase 1 0.0141 0.0507 0.052
Echinococcus multilocularis hypothetical protein 0.0109 0.0327 0.0334
Schistosoma mansoni cercarial elastase (S01 family) 0.0504 0.2524 0.261
Echinococcus granulosus casein kinase I gamma 0.0225 0.0974 0.1005
Schistosoma mansoni egf-like domain protein 0.0357 0.1704 0.1761
Onchocerca volvulus 0.0312 0.1458 0.1505
Brugia malayi RNA binding protein 0.0065 0.0082 0.0083
Brugia malayi TAR-binding protein 0.0065 0.0082 0.0083
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0075 0.0141 0.0141
Brugia malayi Protein kinase domain containing protein 0.0081 0.0173 0.0175
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.0196 0.0809 0.0833
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0088 0.021 0.0209
Echinococcus granulosus cubilin 0.0132 0.0457 0.0468
Schistosoma mansoni tyrosine kinase 0.0296 0.1369 0.1413
Loa Loa (eye worm) hypothetical protein 0.0153 0.0575 0.0575
Loa Loa (eye worm) hypothetical protein 0.0087 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0052 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0076 0.0143 0.0143
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0135 0.0472 0.0484
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0265 0.1197 0.1235
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.006 0.0057 0.0054
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0177 0.0705 0.0726
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0251 0.0255
Brugia malayi Calcium binding EGF domain containing protein 0.014 0.0502 0.0508
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0811 0.0836
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0302 0.1505
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0052 0.0013 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0081 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Echinococcus multilocularis fat cadherin tumor suppressor 0.014 0.0502 0.0515
Plasmodium vivax protein kinase, putative 0.0058 0.0045 0.0037
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0228 0.0991 0.1022
Plasmodium falciparum calcium-dependent protein kinase 1 0.0105 0.0307 0.0309
Toxoplasma gondii PAN/Apple domain-containing protein 0.0282 0.129 0.1328
Onchocerca volvulus 0.1074 0.5691 0.5892
Loa Loa (eye worm) hypothetical protein 0.0061 0.0059 0.0059
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0168 0.0653 0.0668
Giardia lamblia Kinase, CMGC DYRK 0.0146 0.0533 0.402
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0374 0.1802 0.1863
Loa Loa (eye worm) hypothetical protein 0.0148 0.0547 0.0547
Schistosoma mansoni tyrosine kinase 0.0171 0.0675 0.0694
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Loa Loa (eye worm) PAN domain-containing protein 0.0282 0.129 0.129
Echinococcus granulosus dual specificity 0.0146 0.0533 0.0547
Loa Loa (eye worm) hypothetical protein 0.0282 0.129 0.129
Brugia malayi Protein kinase domain containing protein 0.0081 0.0173 0.0175
Trypanosoma brucei cdc2-related kinase 1 0.0124 0.0413 0.2756
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0141 0.0507 0.052
Echinococcus granulosus tyrosine protein kinase Fyn 0.0171 0.0675 0.0694
Onchocerca volvulus Slit protein homolog 0.0172 0.0675 0.0694
Echinococcus multilocularis mitogen activated protein kinase 14 0.0168 0.0653 0.0671
Echinococcus granulosus contactin 0.0052 0.0013 0.0008
Brugia malayi intracellular kinase 0.0135 0.0472 0.0477
Echinococcus granulosus protein jagged 2 0.014 0.0502 0.0515
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0088 0.021 0.1374
Brugia malayi serine/threonine protein kinase 6 0.0153 0.0572 0.0578
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0082 0.008
Schistosoma mansoni protein kinase 0.0131 0.0449 0.046
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0073 0.0128 0.0128
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0087 0.0205 0.0203
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0087 0.0205 0.0205
Echinococcus granulosus serine:threonine protein kinase N2 0.0139 0.0492 0.0505
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0105 0.0307 0.0307
Onchocerca volvulus Putative cubilin 0.0273 0.1237 0.1277
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0075 0.0141 0.0141
Trypanosoma cruzi cdc2-related kinase 3 0.0124 0.0413 0.0419
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0105 0.0307 0.0309
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0153 0.0572 0.0587
Echinococcus multilocularis growth factor receptor bound protein 2 0.0067 0.0093 0.0091
Schistosoma mansoni hypothetical protein 0.1074 0.5691 0.5892
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0062 0.0067 0.0064
Schistosoma mansoni tyrosine kinase 0.0338 0.1602 0.1655
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.0196 0.0809 0.0809
Brugia malayi Protein kinase domain containing protein 0.0477 0.2373 0.2399
Onchocerca volvulus 0.0282 0.129 0.1331
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0105 0.0307 0.0312
Echinococcus granulosus protein kinase c epsilon type 0.0223 0.0961 0.0991
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0235 0.1028 0.106
Echinococcus multilocularis slit 2 protein 0.0172 0.0675 0.0694
Echinococcus multilocularis protein jagged 1 0.014 0.0502 0.0515
Loa Loa (eye worm) hypothetical protein 0.0153 0.0571 0.0571
Brugia malayi enteropeptidase precursor 0.0196 0.0809 0.0818
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.1197 0.1235
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0128 0.0434 0.0441
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Brugia malayi Calcium binding EGF domain containing protein 0.0196 0.0809 0.0818
Plasmodium falciparum serine/threonine protein kinase 0.0142 0.051 0.052
Echinococcus multilocularis casein kinase I delta 0.0114 0.0353 0.0361
Loa Loa (eye worm) TK protein kinase 0.0298 0.138 0.138
Treponema pallidum recombinase A 0.0095 0.0248 0.5
Loa Loa (eye worm) CUB domain-containing protein 0.0132 0.0457 0.0457
Trypanosoma cruzi casein kinase, putative 0.0114 0.0353 0.0357
Entamoeba histolytica protein kinase, putative 0.0177 0.0705 0.3545
Schistosoma mansoni serine/threonine protein kinase 0.0419 0.205 0.2119
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0088 0.021 0.104
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0087 0.0205 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0353 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0205 0.0207
Schistosoma mansoni serine/threonine kinase 0.0229 0.0997 0.1028
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0509 0.0522
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0171 0.0675 0.0694
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.1639 0.1694
Entamoeba histolytica PH domain containing protein kinase, putative 0.0171 0.0675 0.3391
Brugia malayi Fibulin-1 precursor 0.0357 0.1704 0.1723
Leishmania major casein kinase, putative 0.0114 0.0353 0.0357
Echinococcus granulosus tyrosine protein kinase Fyn 0.0171 0.0675 0.0694
Loa Loa (eye worm) hypothetical protein 0.0109 0.0327 0.0327
Entamoeba histolytica protein kinase, putative 0.0107 0.0314 0.1565
Plasmodium falciparum calcium-dependent protein kinase 4 0.0105 0.0307 0.0309
Schistosoma mansoni neuroglian 0.0052 0.0013 0.0008
Echinococcus granulosus titin 0.0069 0.0108 0.0107
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Loa Loa (eye worm) hypothetical protein 0.0196 0.0809 0.0809
Echinococcus multilocularis dual specificity protein kinase clk2 0.0162 0.062 0.0638
Echinococcus granulosus tyrosine protein kinase Fyn 0.0171 0.0675 0.0694
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0389 0.1887 0.195
Brugia malayi putative serine/threonine kinase SADA gamma 0.0093 0.0239 0.0241
Echinococcus granulosus cGMP dependent protein kinase 1 0.0141 0.0507 0.052
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0171 0.0675 0.0694
Echinococcus multilocularis neuropilin (nrp) and tolloid (tll) 0.0132 0.0457 0.0468
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0132 0.0457 0.0465
Echinococcus granulosus notch 0.014 0.0502 0.0515
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0075 0.0141 0.0902
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Loa Loa (eye worm) hypothetical protein 0.0127 0.0429 0.0429
Toxoplasma gondii kringle domain-containing protein 0.1787 0.9655 1
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Trichomonas vaginalis STE family protein kinase 0.0131 0.0449 0.2998
Toxoplasma gondii PAN domain-containing protein 0.0282 0.129 0.1328
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0171 0.0675 0.0694
Loa Loa (eye worm) casein kinase 0.0193 0.0793 0.0793
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0108 0.0107
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0061 0.0359
Brugia malayi Protein kinase domain containing protein 0.0225 0.0974 0.0985
Echinococcus granulosus low density lipoprotein receptor ldl 0.0196 0.0809 0.0833
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0067 0.0093 0.0093
Echinococcus multilocularis rho associated protein kinase 0.0345 0.1639 0.1694
Loa Loa (eye worm) hypothetical protein 0.0504 0.2524 0.2524
Entamoeba histolytica protein kinase, putative 0.0073 0.0128 0.0624
Plasmodium falciparum calcium-dependent protein kinase 3 0.0105 0.0307 0.0309
Schistosoma mansoni hypothetical protein 0.014 0.0502 0.0515
Toxoplasma gondii PAN domain-containing protein 0.0282 0.129 0.1328
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0146 0.0533 0.0544
Schistosoma mansoni tyrosine kinase 0.0487 0.2427 0.2509
Echinococcus multilocularis c src tyrosine kinase 0.0109 0.0326 0.0333
Echinococcus multilocularis mitogen activated protein kinase 14 0.0168 0.0653 0.0671
Brugia malayi GCC2 and GCC3 family protein 0.014 0.0502 0.0508
Echinococcus granulosus casein kinase I delta 0.0114 0.0353 0.0361
Entamoeba histolytica protein kinase, putative 0.0146 0.0533 0.2674
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0272 0.1233 0.1233
Brugia malayi map kinase activated protein kinase protein 2 0.0419 0.205 0.2073
Onchocerca volvulus 0.0119 0.0386 0.0394
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0353 0.2345
Brugia malayi SH2 domain containing protein 0.0081 0.0173 0.0175
Brugia malayi serine/threonine-protein kinase plk-2 0.0286 0.1313 0.1328
Onchocerca volvulus 0.0114 0.0353 0.036
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0075 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0328 0.1544 0.1544
Echinococcus granulosus protein jagged 2 0.014 0.0502 0.0515
Echinococcus granulosus casein kinase I delta 0.0114 0.0353 0.0361
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Trypanosoma cruzi cdc2-related kinase 3 0.0124 0.0413 0.0419
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0439 0.216 0.2233
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.028 0.1278 0.1278
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0142 0.051 0.051
Schistosoma mansoni hypothetical protein 0.0196 0.0809 0.0833
Trichomonas vaginalis AGC family protein kinase 0.0084 0.0191 0.1245
Schistosoma mansoni vav2 0.009 0.0225 0.0228
Plasmodium falciparum calcium-dependent protein kinase 2 0.0105 0.0307 0.0309
Loa Loa (eye worm) hypothetical protein 0.014 0.0502 0.0502
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0082 0.0083
Schistosoma mansoni nephrin 0.0052 0.0013 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Trichomonas vaginalis AGC family protein kinase 0.0316 0.1477 1
Trichomonas vaginalis CAMK family protein kinase 0.0229 0.0997 0.6729
Echinococcus granulosus transmembrane protease serine 3 0.0504 0.2524 0.261
Loa Loa (eye worm) TK/EPH protein kinase 0.0129 0.044 0.044
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0084 0.0191 0.0193
Echinococcus granulosus CUB 0.0132 0.0457 0.0468
Onchocerca volvulus 0.1214 0.6471 0.6701
Toxoplasma gondii microneme protein MIC17A 0.0282 0.129 0.1328
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.1104 0.1139
Brugia malayi Pleckstrin Homology Domain 0.0051 0.0007 0.0007
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0241 0.106 0.1094
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0504 0.2524 0.261
Echinococcus multilocularis neurogenic locus notch protein 0.014 0.0502 0.0515
Schistosoma mansoni microtubule-associated protein tau 0.0605 0.3085 0.3191
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0487 0.2429 0.2512
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0223 0.0961 0.0961
Brugia malayi Variant SH3 domain containing protein 0.0084 0.0188 0.019
Onchocerca volvulus 0.0282 0.129 0.1331
Giardia lamblia Kinase, PLK 0.0286 0.1313 1
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0135 0.0472 0.048
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0105 0.0307 0.0307
Onchocerca volvulus 0.0282 0.129 0.1331
Brugia malayi Protein kinase domain containing protein 0.0422 0.2067 0.209
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0507 0.052
Giardia lamblia Kinase, CMGC CLK 0.0162 0.062 0.4688
Brugia malayi serine/threonine kinase 12 0.0153 0.0572 0.0578
Onchocerca volvulus 0.0132 0.0457 0.0468
Onchocerca volvulus 0.0504 0.2524 0.261
Mycobacterium ulcerans hypothetical protein 0.0504 0.2524 1
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0302 0.1999
Plasmodium falciparum cysteine repeat modular protein 1 0.1787 0.9655 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0105 0.0307 0.0309
Echinococcus multilocularis Glutaredoxin protein 5 0.0132 0.0457 0.0468
Loa Loa (eye worm) hypothetical protein 0.0196 0.0809 0.0809
Echinococcus multilocularis tyrosine protein kinase HCK 0.0105 0.0304 0.0309
Trypanosoma cruzi casein kinase, putative 0.0114 0.0353 0.0357
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0141 0.0507 0.052
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0082 0.0082
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0367 0.176 0.176
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.1237 0.1251
Giardia lamblia Kinase, CMGC GSK 0.0135 0.0472 0.355
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0093 0.0239 0.0239
Echinococcus multilocularis PAK box P21 Rho binding 0.0084 0.0186 0.0188
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0075 0.0136 0.087
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0067 0.0093 0.0091
Loa Loa (eye worm) TK/FER protein kinase 0.0081 0.0173 0.0173
Giardia lamblia Kinase, CAMK CAMKL 0.0093 0.0239 0.1762
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0084 0.0188 0.0189
Brugia malayi Protein kinase domain containing protein 0.0336 0.1588 0.1606
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0171 0.0675 0.0694
Onchocerca volvulus 0.0196 0.0809 0.0833
Echinococcus multilocularis laminin 0.0357 0.1704 0.1761
Brugia malayi Fibronectin type III domain containing protein 0.0077 0.015 0.0152
Echinococcus multilocularis dual specificity 0.0146 0.0533 0.0547
Schistosoma mansoni hypothetical protein 0.027 0.1222 0.1261
Schistosoma mansoni hypothetical protein 0.014 0.0502 0.0515
Echinococcus granulosus tissue type plasminogen activator 0.1787 0.9655 1
Echinococcus multilocularis protein kinase shaggy 0.0135 0.0472 0.0484
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0114 0.0353 0.0353
Echinococcus multilocularis tyrosine protein kinase shark 0.0309 0.1441 0.1488
Entamoeba histolytica cell division protein kinase 2, putative 0.0124 0.0413 0.2067
Echinococcus granulosus protein jagged 1 0.014 0.0502 0.0515
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0109 0.0326 0.0333
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0081 0.0173 0.0848
Echinococcus granulosus NCK adaptor protein 0.0067 0.0093 0.0091
Echinococcus multilocularis cyclin dependent kinase 5 0.0124 0.0413 0.0423
Echinococcus granulosus tyrosine protein kinase shark 0.0309 0.1441 0.1488
Trypanosoma cruzi p21-activated kinase 3, putative 0.008 0.0166 0.0163
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0131 0.0449 0.046
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.0132 0.0457 0.0468
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0135 0.0472 0.0484
Brugia malayi Sex muscle abnormal protein 5 0.0067 0.0093 0.0094
Echinococcus granulosus casein kinase I alpha 0.0114 0.0353 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0374 0.1802 0.1863
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0961 0.0991
Echinococcus granulosus neurogenic locus notch protein 4 0.014 0.0502 0.0515
Echinococcus multilocularis casein kinase I gamma 0.0225 0.0974 0.1005
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0141 0.0141
Brugia malayi SEA domain containing protein 0.1074 0.5691 0.5755
Loa Loa (eye worm) TK/FER protein kinase 0.0081 0.0173 0.0173
Brugia malayi PAN domain containing protein 0.0282 0.129 0.1304
Entamoeba histolytica protein kinase, putative 0.0135 0.0472 0.2364
Loa Loa (eye worm) hypothetical protein 0.0282 0.129 0.129
Loa Loa (eye worm) hypothetical protein 0.0119 0.0385 0.0385
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Loa Loa (eye worm) hypothetical protein 0.0129 0.0439 0.0439
Leishmania major protein kinase, putative 0.0162 0.062 0.0634
Onchocerca volvulus 0.0081 0.0173 0.0173
Trypanosoma brucei cdc2-related kinase 3 0.0124 0.0413 0.2756
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0526 0.2645 0.2736
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0132 0.0457 0.0457
Echinococcus granulosus defective proboscis extension response 0.006 0.0057 0.0054
Echinococcus granulosus Mastin 0.0504 0.2524 0.261
Loa Loa (eye worm) TK/FER protein kinase 0.0081 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0325 0.153 0.153
Schistosoma mansoni protein kinase 0.0114 0.0353 0.0361
Plasmodium vivax serine/threonine kinase-1, putative 0.0162 0.062 0.0634
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0084 0.0191 0.0191
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0472 0.2364
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0052 0.0013 0.0008
Trypanosoma cruzi cdc2-related kinase 1 0.0124 0.0413 0.0419
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0171 0.0675 0.0694
Brugia malayi Zinc metalloproteinase toh-2 precursor 0.0132 0.0457 0.0462
Schistosoma mansoni ste20-related kinase 0.0217 0.0926 0.0955
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0119 0.0386 0.0395
Echinococcus granulosus mitogen activated protein kinase 0.0087 0.0205 0.0207
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0228 0.0991 0.1022
Brugia malayi Delta serrate ligand family protein 0.014 0.0502 0.0508
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0682 0.0702
Entamoeba histolytica protein kinase, putative 0.0309 0.144 0.7265
Brugia malayi Protein kinase domain containing protein 0.0173 0.0682 0.069
Brugia malayi Protein kinase domain containing protein 0.1004 0.5305 0.5364
Loa Loa (eye worm) hypothetical protein 0.0552 0.2791 0.2791
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0265 0.1194 0.1228
Brugia malayi Temporarily assigned gene name protein 59 0.0138 0.0488 0.0494
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0477 0.2373 0.2373
Plasmodium falciparum calcium-dependent protein kinase 5 0.0105 0.0307 0.0309
Echinococcus granulosus insulin receptor 0.0422 0.2067 0.2137
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0235 0.1028 0.106
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0254 0.1133 0.1169
Loa Loa (eye worm) hypothetical protein 0.0282 0.129 0.129
Schistosoma mansoni cell polarity protein 0.014 0.0502 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0239 0.1566
Entamoeba histolytica protein kinase domain containing protein 0.0128 0.0434 0.217
Brugia malayi RNA, U transporter 1 0.0072 0.0121 0.0123
Brugia malayi protein kinase C II. 0.0223 0.0961 0.0972
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0128 0.0434 0.0441
Leishmania major protein kinase, putative 0.0153 0.0572 0.0584
Echinococcus multilocularis neuroglian 0.0052 0.0013 0.0008
Brugia malayi astacin protease protein 30 0.0132 0.0457 0.0462
Toxoplasma gondii CMGC kinase, CK2 family 0.0104 0.0302 0.0304
Echinococcus multilocularis cyclin dependent kinase 1 0.0124 0.0413 0.0423
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0153 0.0572 0.0584
Loa Loa (eye worm) TK/FAK protein kinase 0.0316 0.1477 0.1477
Echinococcus granulosus tyrosine protein kinase 0.0298 0.138 0.1425
Brugia malayi CUB domain containing protein 0.0132 0.0457 0.0462
Loa Loa (eye worm) SRC-1 0.0171 0.0675 0.0675
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0142 0.051 0.052
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0131 0.0449 0.046
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0162 0.062 0.4166
Onchocerca volvulus 0.0282 0.129 0.1331
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0302 0.1999
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.1104 0.1139
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0229 0.0997 0.0997
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0162 0.062 0.0634
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0095 0.0248 0.5
Echinococcus multilocularis Tolloid protein 1 0.0489 0.2439 0.2522
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0075 0.0136 0.0132
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1463 0.7851 0.9333
Schistosoma mansoni hypothetical protein 0.014 0.0502 0.0515
Echinococcus multilocularis roundabout 2 0.0052 0.0013 0.0008
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0526 0.2645 0.2736
Giardia lamblia Kinase, CAMK CAMKL 0.0093 0.0239 0.1762
Loa Loa (eye worm) hypothetical protein 0.1294 0.6913 0.6913
Echinococcus multilocularis epidermal growth factor receptor 0.0487 0.2427 0.2509
Toxoplasma gondii subtilisin SUB12 0.0282 0.129 0.1328
Trichomonas vaginalis AGC family protein kinase 0.0199 0.0827 0.5572
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0009 0.0004
Giardia lamblia Kinase, CMGC SRPK 0.0142 0.051 0.3846
Onchocerca volvulus 0.0282 0.129 0.1331
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.1028 0.106
Loa Loa (eye worm) hypothetical protein 0.0336 0.1588 0.1588
Brugia malayi Protein kinase domain containing protein 0.0298 0.138 0.1395
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0067 0.0093 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0054 0.0025 0.0109
Brugia malayi Kelch motif family protein 0.0132 0.0457 0.0462
Schistosoma mansoni cell adhesion molecule 0.0052 0.0013 0.0008
Brugia malayi Variant SH3 domain containing protein 0.0067 0.0093 0.0094
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0142 0.051 0.052
Trichomonas vaginalis STE family protein kinase 0.0143 0.0516 0.3457
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0504 0.2524 0.261
Brugia malayi protein unc-22 0.0069 0.0108 0.0109
Onchocerca volvulus 0.0197 0.0819 0.0843
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0991 0.1022
Brugia malayi Trypsin family protein 0.0504 0.2524 0.2553
Entamoeba histolytica protein kinase, putative 0.0084 0.0191 0.0944
Loa Loa (eye worm) PAN domain-containing protein 0.0282 0.129 0.129
Trichomonas vaginalis STE family protein kinase 0.0084 0.0186 0.121

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 38 uM Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytes ChEMBL. 7629795
IC50 (binding) = 126 uM Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1) ChEMBL. 7629795

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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