Detailed information for compound 1564576

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 367.438 | Formula: C22H25NO4
  • H donors: 0 H acceptors: 1 LogP: 4.69 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C1=NOC(C1)CC(=O)Oc1cc(C)ccc1C(C)C
  • InChi: 1S/C22H25NO4/c1-14(2)19-10-5-15(3)11-21(19)26-22(24)13-18-12-20(23-27-18)16-6-8-17(25-4)9-7-16/h5-11,14,18H,12-13H2,1-4H3
  • InChiKey: YZWPLPYRHPWZBP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0062 0.0105
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0013 0.0016
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0041 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0155 0.0273
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0111 0.0266 0.0474
Loa Loa (eye worm) MH2 domain-containing protein 0.0043 0.0071 0.0126
Brugia malayi hypothetical protein 0.0257 0.0684 0.1233
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0013
Schistosoma mansoni hypothetical protein 0.0897 0.2524 0.3958
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.0012 0.0062
Plasmodium falciparum alpha tubulin 1 0.1406 0.3988 0.7202
Trichomonas vaginalis tubulin gamma chain, putative 0.1945 0.5535 1
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0009 0.0029
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0074 0.0072
Brugia malayi Raf kinase 0.0046 0.008 0.014
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.0012 0.0062
Mycobacterium ulcerans epimerase 0.0021 0.0009 0.0032
Trypanosoma brucei alpha tubulin 0.1406 0.3988 0.7202
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0078 0.017 0.0299
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1945 0.5535 0.5534
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0081 0.0143
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0351 0.2688
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0046 0.0079 0.0136
Schistosoma mansoni regulator of G protein signaling 0.0046 0.008 0.0125
Brugia malayi PXA domain containing protein 0.0046 0.008 0.014
Loa Loa (eye worm) RecQ helicase 0.0044 0.0074 0.0131
Loa Loa (eye worm) hypothetical protein 0.0071 0.0151 0.027
Leishmania major epsilon tubulin, putative 0.1073 0.3031 0.5472
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0036 0.006
Loa Loa (eye worm) tubulin alpha-2 chain 0.1406 0.3988 0.7204
Mycobacterium ulcerans 6-phosphofructokinase 0.0116 0.0282 0.2151
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.0012 0.0062
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0031 0.0036 0.0052
Loa Loa (eye worm) phosphatidylinositol 3 0.0097 0.0227 0.0408
Echinococcus multilocularis transfer RNA-Lys 0.0155 0.0393 0.0391
Brugia malayi tailless protein 0.0031 0.0036 0.006
Brugia malayi sodium-independent organic anion transporter family protein 0.0091 0.0209 0.0373
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.0012 0.0062
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0013 0.0011
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0211 0.0554 0.0994
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0045 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0223 0.0349
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0035 0.0049 0.008
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0036 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.0012 0.0062
Loa Loa (eye worm) tubulin alpha 2 0.0937 0.2641 0.477
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.0282 0.0501
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0023 0.0012 0.0014
Brugia malayi SPARC precursor 0.0062 0.0126 0.0223
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0023 0.0033
Trypanosoma cruzi epsilon tubulin, putative 0.1073 0.3031 0.5472
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0041 0.0066
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0037 0.006
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0049 0.008
Leishmania major cytochrome p450-like protein 0.0023 0.0012 0.0014
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0066 0.0064
Brugia malayi tubulin alpha chain - mouse 0.1406 0.3988 0.7204
Trypanosoma cruzi tubulin delta chain 0.0652 0.1819 0.3282
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0011 0.0008
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0046 0.008 0.0125
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0049 0.0343
Plasmodium vivax multidomain scavenger receptor, putative 0.0171 0.0438 0.0783
Trypanosoma cruzi zeta tubulin, putative 0.0774 0.2172 0.392
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0055 0.0104 0.018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0036 0.0033
Plasmodium vivax glutathione reductase, putative 0.0102 0.024 0.0426
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0045 0.0072
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0037 0.006
Toxoplasma gondii beta-1 tubulin, putative 0.1945 0.5535 1
Trypanosoma cruzi epsilon tubulin, putative 0.1073 0.3031 0.5472
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0049 0.008
Echinococcus multilocularis axis inhibition protein axin 0.0046 0.008 0.0077
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0261 0.0698 0.1259
Loa Loa (eye worm) hypothetical protein 0.0091 0.0208 0.0373
Echinococcus granulosus CREB binding protein 0.0036 0.005 0.0075
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0045 0.0072
Brugia malayi hypothetical protein 0.0031 0.0036 0.006
Loa Loa (eye worm) hypothetical protein 0.0071 0.0151 0.027
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0013 0.0016
Trypanosoma brucei alpha tubulin, putative 0.0575 0.16 0.2885
Toxoplasma gondii target of rapamycin (TOR), putative 0.0072 0.0155 0.0273
Giardia lamblia Beta tubulin 0.1945 0.5535 1
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0937 0.2641 0.477
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0037 0.006
Toxoplasma gondii NADPH-glutathione reductase 0.0035 0.0049 0.008
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Echinococcus multilocularis dnaJ subfamily B 0.0878 0.247 0.2468
Brugia malayi hypothetical protein 0.0384 0.1051 0.1895
Brugia malayi hypothetical protein 0.0031 0.0036 0.006
Loa Loa (eye worm) nuclear hormone receptor 0.0031 0.0036 0.0062
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0033 0.0041 0.0039
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0044 0.0071
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0035 0.0049 0.008
Brugia malayi secreted modular calcium-binding protein 1 0.0062 0.0126 0.0223
Plasmodium falciparum alpha tubulin 2 0.1406 0.3988 0.7202
Trichomonas vaginalis taga, putative 0.0023 0.0013 0.0016
Echinococcus multilocularis aryl hydrocarbon receptor 0.0055 0.0104 0.0101
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0045 0.0072
Trypanosoma brucei tubulin gamma chain 0.1074 0.3032 0.5475
Schistosoma mansoni retinoic acid receptor RXR 0.0071 0.0151 0.0237
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0087 0.0196 0.0353
Schistosoma mansoni cytochrome P450 0.0023 0.0012 0.0019
Echinococcus granulosus ecdysone induced protein 78C 0.0071 0.0151 0.0233
Brugia malayi Pax transcription factor protein 2 0.0261 0.0698 0.1256
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0062 0.006
Schistosoma mansoni hypothetical protein 0.0878 0.247 0.3874
Trichomonas vaginalis tubulin gamma chain, putative 0.1073 0.3031 0.5472
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0266 0.0474
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0045 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0062 0.0105
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0045 0.007
Brugia malayi Tubulin alpha chain 0.1406 0.3988 0.7204
Toxoplasma gondii LsmAD domain-containing protein 0.0109 0.026 0.0461
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0033 0.0041 0.0064
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.026 0.0461
Echinococcus multilocularis lamin 0.0087 0.0196 0.0194
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0182 0.0286
Brugia malayi hypothetical protein 0.0207 0.0541 0.0974
Echinococcus multilocularis CREB binding protein 0.0036 0.005 0.0048
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0055 0.0104 0.018
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0151 0.0268
Trichomonas vaginalis tubulin gamma chain, putative 0.1074 0.3032 0.5475
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0155 0.0273
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0035 0.0049 0.008
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0037 0.006
Leishmania major delta tubulin, putative 0.0652 0.1819 0.3282
Trichomonas vaginalis helicase, putative 0.002 0.0006 0.0002
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0575 0.16 0.2885
Loa Loa (eye worm) hypothetical protein 0.0091 0.0209 0.0374
Leishmania major beta tubulin 0.1945 0.5535 1
Loa Loa (eye worm) intermediate filament protein 0.0087 0.0196 0.0353
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0013 0.0011
Trichomonas vaginalis tubulin epsilon chain, putative 0.1945 0.5535 1
Onchocerca volvulus 0.0091 0.0209 0.0985
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1406 0.3988 0.7202
Loa Loa (eye worm) tubulin alpha 2 0.0362 0.0988 0.1783
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0033 0.0041 0.0066
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0013 0.0016
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0031 0.0036 0.0056
Schistosoma mansoni organic anion transporter 0.0091 0.0209 0.0327
Loa Loa (eye worm) tubulin beta chain 0.1945 0.5535 1
Echinococcus granulosus smad 0.0043 0.0071 0.0107
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0002
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0013 0.0011
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0831 0.2335 0.4213
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0062 0.0098
Echinococcus multilocularis Regulator of G protein signaling 20 0.0046 0.008 0.0077
Schistosoma mansoni hypothetical protein 0.0023 0.0012 0.0019
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0013 0.0016
Echinococcus multilocularis tubulin alpha chain 0.1406 0.3988 0.3986
Trypanosoma brucei alpha tubulin 0.1406 0.3988 0.7202
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0036 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0006 0.0003
Schistosoma mansoni tubulin subunit gamma 0.1074 0.3032 0.4755
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Trichomonas vaginalis tubulin epsilon chain, putative 0.1945 0.5535 1
Echinococcus granulosus Tubulin beta 2C chain 0.1945 0.5535 0.8679
Plasmodium vivax multidrug resistance protein 1, putative 0.0023 0.0013 0.0016
Echinococcus granulosus dnaJ subfamily B 0.0878 0.247 0.3871
Schistosoma mansoni tubulin subunit beta 0.1945 0.5535 0.8679
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0002
Giardia lamblia NADH oxidase lateral transfer candidate 0.0035 0.0049 0.008
Giardia lamblia Fructose-bisphosphate aldolase 0.0288 0.0774 0.1392
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0013 0.0016
Leishmania major beta tubulin 0.1945 0.5535 1
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0266 0.0474
Echinococcus granulosus Protein patched homolog 1 0.0091 0.0208 0.0322
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0282 0.0501
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0071 0.0151 0.0237
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0037 0.006
Trypanosoma brucei alpha tubulin 0.1406 0.3988 0.7202
Loa Loa (eye worm) hypothetical protein 0.0091 0.0209 0.0374
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Leishmania major protein kinase, putative 0.0056 0.0107 0.0185
Loa Loa (eye worm) multidrug resistance protein 3 0.0023 0.0013 0.0022
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0071 0.0151 0.071
Trichomonas vaginalis tubulin beta chain, putative 0.1406 0.3988 0.7202
Brugia malayi prostaglandin transporter 0.0091 0.0209 0.0373
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0013 0.0016
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.0153 0.0274
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0056 0.0107 0.0185
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0012 0.0014
Echinococcus multilocularis beta tubulin 0.1945 0.5535 0.5534
Toxoplasma gondii tubulin, putative 0.0029 0.0031 0.0048
Mycobacterium tuberculosis Probable dehydrogenase 0.0233 0.0616 0.4741
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0151 0.0237
Echinococcus granulosus jun protein 0.0263 0.0704 0.11
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) transcription factor SMAD2 0.0633 0.1765 0.3187
Schistosoma mansoni cpg binding protein 0.0095 0.022 0.0345
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0005
Onchocerca volvulus 0.0023 0.0013 0.0053
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.0012 0.0062
Trypanosoma cruzi trypanothione reductase, putative 0.0102 0.024 0.0426
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0098 0.017
Echinococcus multilocularis peroxisome assembly protein 26 0.1406 0.3988 0.3986
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0091 0.0209 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0469 0.1294 0.2332
Schistosoma mansoni tubulin subunit beta 0.1945 0.5535 0.8679
Loa Loa (eye worm) hypothetical protein 0.0087 0.0196 0.0353
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0097 0.0227 0.0402
Onchocerca volvulus 0.0055 0.0104 0.0485
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0111 0.0266 0.0479
Mycobacterium tuberculosis Cell division protein FtsZ 0.0469 0.1294 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0035 0.0049 0.0343
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0013 0.0011
Leishmania major beta tubulin 0.1945 0.5535 1
Brugia malayi hypothetical protein 0.0109 0.026 0.0465
Loa Loa (eye worm) hypothetical protein 0.0055 0.0104 0.0185
Leishmania major beta tubulin 0.1945 0.5535 1
Echinococcus multilocularis expressed protein 0.0803 0.2255 0.2253
Echinococcus granulosus tubulin alpha 1C chain 0.1406 0.3988 0.6252
Onchocerca volvulus 0.0031 0.0036 0.0158
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0037 0.0035
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0233 0.0616 0.4741
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0013 0.0016
Brugia malayi isocitrate dehydrogenase 0.0034 0.0045 0.0076
Trichomonas vaginalis tubulin epsilon chain, putative 0.1406 0.3988 0.7202
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0469 0.1294 1
Loa Loa (eye worm) hypothetical protein 0.0256 0.0683 0.1232
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.008 0.0136
Onchocerca volvulus 0.0575 0.16 0.7637
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0002 0.0002
Brugia malayi nuclear receptor NHR-88 0.0071 0.0151 0.0268
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.0227 0.0402
Echinococcus granulosus thioredoxin glutathione reductase 0.0102 0.024 0.0373
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0023 0.0013 0.007
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0062 0.006
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.0153 0.0151
Loa Loa (eye worm) hypothetical protein 0.0062 0.0126 0.0225
Echinococcus granulosus Regulator of G protein signaling 20 0.0046 0.008 0.0121
Brugia malayi Steroid receptor seven-up type 2 0.0071 0.0151 0.0268
Giardia lamblia Beta tubulin 0.1945 0.5535 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0013 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0098 0.0169
Plasmodium falciparum glutathione reductase 0.0102 0.024 0.0426
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0046 0.008 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0071 0.0151 0.0268
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.0282 0.0501
Schistosoma mansoni nuclear receptor 0.0031 0.0036 0.0056
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Toxoplasma gondii beta tubulin 0.1945 0.5535 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0049 0.0087 0.0085
Echinococcus multilocularis raf serine:threonine protein kinase 0.0046 0.008 0.0077
Echinococcus multilocularis Tubulin beta 2C chain 0.1945 0.5535 0.5534
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0126 0.0219
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0066 0.0111
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0009 0.0011
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.0282 0.0501
Entamoeba histolytica recQ family helicase, putative 0.0034 0.0044 0.0071
Loa Loa (eye worm) MH2 domain-containing protein 0.0633 0.1765 0.3187
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0045 0.0042
Echinococcus multilocularis thioredoxin glutathione reductase 0.0102 0.024 0.0238
Schistosoma mansoni jumonji domain containing protein 0.0064 0.013 0.0205
Trypanosoma cruzi beta tubulin, putative 0.1945 0.5535 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.0012 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.008 0.0136
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0098 0.017
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0013 0.0016
Echinococcus multilocularis tubulin alpha chain 0.1406 0.3988 0.3986
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.004 0.0063 0.0106
Echinococcus granulosus axis inhibition protein axin 0.0046 0.008 0.0121
Treponema pallidum NADH oxidase 0.0035 0.0049 0.0343
Echinococcus multilocularis neuropeptide receptor A26 0.0997 0.2811 0.281
Echinococcus multilocularis Tubulin beta 2C chain 0.1945 0.5535 0.5534
Trypanosoma brucei protein kinase, putative 0.0111 0.0266 0.0474
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.0282 0.0507
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0937 0.2641 0.4767
Brugia malayi bHLH-PAS transcription factor 0.0155 0.0393 0.0707
Plasmodium vivax tubulin alpha chain, putative 0.1406 0.3988 0.7202
Brugia malayi TAZ zinc finger family protein 0.0219 0.0577 0.1038
Echinococcus granulosus Tubulin beta 2C chain 0.1945 0.5535 0.8679
Trichomonas vaginalis tubulin beta chain, putative 0.1406 0.3988 0.7202
Echinococcus multilocularis cpg binding protein 0.0095 0.022 0.0218
Echinococcus granulosus regulator of G protein signaling 7 0.0046 0.008 0.0121
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0045 0.0042
Loa Loa (eye worm) hypothetical protein 0.0091 0.0209 0.0374
Brugia malayi nuclear hormone receptor family member odr-7 0.0031 0.0036 0.006
Echinococcus granulosus neuropeptide receptor A26 0.0997 0.2811 0.4406
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.004 0.0062 0.011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0049 0.008
Giardia lamblia Epsilon tubulin 0.0498 0.1378 0.2483
Loa Loa (eye worm) hypothetical protein 0.0091 0.0209 0.0374
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.0282 0.0442
Brugia malayi alpha-tubulin 0.1406 0.3988 0.7204
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0091 0.0209 0.0374
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0035 0.0049 0.008
Brugia malayi Niemann-Pick C1 protein precursor 0.0211 0.0554 0.0998
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.0282 0.0442
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0116 0.0282 0.2151
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0263 0.0704 0.11
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0151 0.0149
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0037 0.006
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0141
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0116 0.0282 0.2151
Loa Loa (eye worm) doublecortin family protein 0.0171 0.0438 0.0788
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0132 0.0204
Trypanosoma brucei alpha tubulin 0.1406 0.3988 0.7202
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0141
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0002
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0126 0.0219
Schistosoma mansoni lamin 0.0087 0.0196 0.0308
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0282 0.0501
Brugia malayi nuclear receptor RXR 0.004 0.0062 0.0108
Echinococcus granulosus geminin 0.0897 0.2524 0.3956
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0062 0.0094
Schistosoma mansoni hypothetical protein 0.0049 0.0087 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.017 0.0299
Echinococcus granulosus single minded 2 0.0155 0.0393 0.0613
Echinococcus multilocularis lysine specific demethylase 5A 0.0064 0.013 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0071 0.0151 0.027
Loa Loa (eye worm) nuclear receptor NHR-67 0.0031 0.0036 0.0062
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0013 0.0016
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0013 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0049 0.008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Trypanosoma cruzi trypanothione reductase, putative 0.0035 0.0049 0.008
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0013 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0114 0.0199
Echinococcus granulosus alpha tubulin 0.1406 0.3988 0.6252
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0097 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0041 0.0066
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.0012 0.0062
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Leishmania major beta tubulin 0.1945 0.5535 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0056 0.0107 0.0185
Echinococcus multilocularis tumor protein p63 0.1469 0.4168 0.4167
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0035 0.0049 0.0073
Schistosoma mansoni nuclear receptor 0.0031 0.0036 0.0056
Onchocerca volvulus 0.0155 0.0393 0.1869
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0036 0.0061
Plasmodium falciparum tubulin epsilon chain, putative 0.1073 0.3031 0.5472
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0002
Loa Loa (eye worm) alpha-tubulin 0.1406 0.3988 0.7204
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0002
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.0029 0.0045
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0023 0.0012 0.0062
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0071 0.0151 0.0233
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.0153 0.024
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0147 0.0257
Brugia malayi CHE-14 protein 0.0091 0.0208 0.0371
Brugia malayi Tubulin beta-1 chain 0.1945 0.5535 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0047 0.0081 0.0144
Loa Loa (eye worm) hypothetical protein 0.004 0.0063 0.0111
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.011
Brugia malayi hypothetical protein 0.0704 0.197 0.3557
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0062 0.0105
Trichomonas vaginalis set domain proteins, putative 0.0747 0.2094 0.3778
Loa Loa (eye worm) hypothetical protein 0.0042 0.0067 0.0119
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0013 0.0016
Schistosoma mansoni microtubule-associated protein tau 0.2238 0.6377 1
Echinococcus granulosus Niemann Pick C1 protein 0.0211 0.0554 0.0866
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.017 0.0299
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0071 0.0151 0.0237
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0013 0.0011
Echinococcus granulosus Smad4 0.0043 0.0071 0.0107
Trypanosoma brucei cytochrome P450, putative 0.0069 0.0147 0.0257
Echinococcus multilocularis axis inhibition protein axin 0.0046 0.008 0.0077
Brugia malayi 6-phosphofructokinase 0.0116 0.0282 0.0505
Trichomonas vaginalis tubulin alpha chain, putative 0.0575 0.16 0.2885
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.0012 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.0012 0.0062
Trichomonas vaginalis tubulin beta chain, putative 0.1406 0.3988 0.7202
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0062 0.0126 0.0223
Brugia malayi Cell division protein ftsZ 0.0469 0.1294 0.2334
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Echinococcus multilocularis Tubulin alpha 1 chain 0.1406 0.3988 0.3986
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0049 0.008
Loa Loa (eye worm) hypothetical protein 0.0704 0.197 0.3558
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0035 0.0049 0.008
Echinococcus granulosus tubulin delta chain 0.0469 0.1294 0.2026
Echinococcus granulosus lysine specific demethylase 5A 0.0069 0.0145 0.0224
Echinococcus multilocularis 6 phosphofructokinase 0.0116 0.0282 0.0279
Trypanosoma cruzi zeta tubulin, putative 0.0774 0.2172 0.392
Giardia lamblia Alpha-tubulin 0.1406 0.3988 0.7202
Echinococcus granulosus tubulin alpha chain 0.1406 0.3988 0.6252
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0145 0.0228
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0097 0.0227 0.0402
Leishmania major beta tubulin 0.1945 0.5535 1
Plasmodium vivax tubulin beta chain, putative 0.1945 0.5535 1
Toxoplasma gondii alpha tubulin TUBA1 0.1406 0.3988 0.7202
Echinococcus granulosus regulator of G protein signaling 3 0.0046 0.008 0.0121
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0035 0.0049 0.2112
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0062 0.0105
Leishmania major ATP-dependent phosphofructokinase 0.0116 0.0282 0.0501
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0047 0.0082 0.0145
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0085 0.0192 0.0344
Echinococcus granulosus aryl hydrocarbon receptor 0.0055 0.0104 0.0159
Entamoeba histolytica hypothetical protein 0.019 0.0494 0.0886
Trichomonas vaginalis conserved hypothetical protein 0.0469 0.1294 0.2332
Brugia malayi Intermediate filament tail domain containing protein 0.0087 0.0196 0.0351
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0049 0.008
Echinococcus multilocularis tubulin delta chain 0.0469 0.1294 0.1292
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.0012 0.0062
Schistosoma mansoni hypothetical protein 0.019 0.0494 0.0775
Brugia malayi bZIP transcription factor family protein 0.0263 0.0704 0.1267
Echinococcus multilocularis tubulin subunit beta 0.1945 0.5535 0.5534
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0046 0.008 0.0141
Schistosoma mansoni tubulin subunit delta 0.0469 0.1294 0.2029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0132 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0041 0.0066
Trichomonas vaginalis abcb9, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) tubulin beta-4 chain 0.1945 0.5535 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0037 0.0256
Echinococcus multilocularis Tubulin beta 2C chain 0.1945 0.5535 0.5534
Echinococcus granulosus Tubulin beta 2C chain 0.1945 0.5535 0.8679
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0071 0.0151 0.0149
Trypanosoma cruzi alpha tubulin, putative 0.1406 0.3988 0.7202
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0021 0.0019
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0037 0.006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0132 0.0991
Echinococcus granulosus cpg binding protein 0.0095 0.022 0.0342
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.0012 0.0062
Loa Loa (eye worm) tubulin beta-1 chain 0.1945 0.5535 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0155 0.0273
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Plasmodium falciparum LCCL domain-containing protein 0.0171 0.0438 0.0783
Echinococcus multilocularis tubulin beta 1 chain 0.1945 0.5535 0.5534
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0151 0.0237
Brugia malayi beta-tubulin, identical 0.1945 0.5535 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.0282 0.0507
Echinococcus granulosus lamin 0.0087 0.0196 0.0304
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0151 0.0268
Echinococcus multilocularis musashi 0.0087 0.0196 0.0194
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.026 0.0461
Schistosoma mansoni smad1 5 8 and 0.0043 0.0071 0.0111
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.0012 0.0062
Schistosoma mansoni hypothetical protein 0.0214 0.0562 0.0881
Loa Loa (eye worm) hypothetical protein 0.0071 0.0151 0.027
Brugia malayi regulator of G-protein signaling egl-10 0.0046 0.008 0.014
Schistosoma mansoni aryl hydrocarbon receptor 0.021 0.055 0.0863
Brugia malayi MH2 domain containing protein 0.0633 0.1765 0.3186
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0681 0.1904 0.2983
Leishmania major cytochrome p450-like protein 0.0023 0.0012 0.0014
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0071 0.0151 0.0233
Trypanosoma brucei beta tubulin 0.1945 0.5535 1
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.0282 0.0501
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0155 0.0273
Echinococcus multilocularis tubulin alpha chain 0.1406 0.3988 0.3986
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0049 0.008
Schistosoma mansoni hypothetical protein 0.0087 0.0198 0.0311
Echinococcus multilocularis tubulin alpha chain 0.1406 0.3988 0.3986
Schistosoma mansoni multidrug resistance protein 0.0023 0.0013 0.0021
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0013 0.0016
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0006 0.0002
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0097 0.0227 0.0225
Echinococcus multilocularis CREB binding protein 0.0036 0.005 0.0048
Schistosoma mansoni alpha tubulin 0.1406 0.3988 0.6253
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.0012 0.0062
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0021 0.0033
Brugia malayi hypoxia-induced factor 1 0.065 0.1814 0.3274
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0013 0.0016
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0046 0.008 0.0125
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0097 0.0227 0.0402
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0043 0.0071 0.0111
Loa Loa (eye worm) hypothetical protein 0.0062 0.0126 0.0225
Schistosoma mansoni tubulin subunit beta 0.1945 0.5535 0.8679
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0091 0.0209 0.0374
Leishmania major gamma-tubulin 0.1074 0.3032 0.5475
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0062 0.0094
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0037 0.006
Loa Loa (eye worm) CXXC zinc finger family protein 0.009 0.0205 0.0369
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.004 0.0062 0.0094
Brugia malayi Thioredoxin reductase 0.0102 0.024 0.043
Brugia malayi Tubulin beta chain 0.0469 0.1294 0.2334
Echinococcus granulosus TGF beta signal transducer SmadC 0.0043 0.0071 0.0107
Brugia malayi nuclear receptor RXR 0.0031 0.0036 0.006
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0013 0.0068
Echinococcus granulosus lipoxygenase domain containing protein 0.0171 0.0438 0.0683
Echinococcus granulosus Solute carrier organic anion transporter family 0.0091 0.0209 0.0323
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0141
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0652 0.1819 0.3282
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0045 0.0066
Loa Loa (eye worm) tubulin gamma chain 0.1074 0.3032 0.5477
Echinococcus multilocularis Polycystic kidney disease protein 0.0171 0.0438 0.0435
Echinococcus multilocularis hypothetical protein 0.1406 0.3988 0.3986
Echinococcus granulosus tubulin alpha 3 chain 0.1406 0.3988 0.6252
Loa Loa (eye worm) hypothetical protein 0.0071 0.0151 0.027
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Echinococcus granulosus CREB binding protein 0.0219 0.0577 0.0901
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0223 0.0345
Onchocerca volvulus 0.0091 0.0209 0.0985
Echinococcus granulosus tubulin beta 1 chain 0.1945 0.5535 0.8679
Echinococcus granulosus tubulin epsilon chain 0.1073 0.3031 0.4751
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0055 0.0104 0.018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.0227 0.0402
Trichomonas vaginalis guanylate cyclase, putative 0.0055 0.0104 0.018
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0153 0.0268
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0062 0.0126 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.017 0.0299
Plasmodium falciparum glutathione reductase 0.0035 0.0049 0.008
Echinococcus multilocularis tubulin alpha 1C chain 0.1406 0.3988 0.3986
Brugia malayi Pre-SET motif family protein 0.0096 0.0223 0.0398
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0071 0.0151 0.0149
Onchocerca volvulus 0.0096 0.0223 0.1052
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0002
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0031 0.0036 0.0056
Brugia malayi nuclear hormone receptor 0.0071 0.0151 0.0268
Brugia malayi Pre-SET motif family protein 0.0657 0.1834 0.3311
Loa Loa (eye worm) tubulin alpha chain 0.1406 0.3988 0.7204
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0036 0.0057
Trichomonas vaginalis tubulin alpha chain, putative 0.1044 0.2947 0.5321
Brugia malayi hypothetical protein 0.0046 0.008 0.014
Schistosoma mansoni smad1 5 8 and 0.0043 0.0071 0.0111
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0045 0.0042
Plasmodium vivax ataxin-2 like protein, putative 0.0109 0.026 0.0461
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0151 0.0268
Loa Loa (eye worm) steroid hormone receptor 0.0071 0.0151 0.027
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0023 0.0013 0.0016
Leishmania major phosphatidylinositol 3-kinase, putative 0.0033 0.0041 0.0066
Entamoeba histolytica P-glycoprotein-5 0.0023 0.0013 0.0016
Echinococcus multilocularis jun protein 0.0263 0.0704 0.0701
Brugia malayi Cytochrome P450 family protein 0.0023 0.0012 0.0018
Toxoplasma gondii alpha-tubulin I, putative 0.1406 0.3988 0.7202
Echinococcus granulosus CREB binding protein 0.0135 0.0335 0.0522
Trichomonas vaginalis DNA helicase recq, putative 0.0034 0.0044 0.0071
Brugia malayi Regulator of G protein signaling domain containing protein 0.0046 0.008 0.014
Schistosoma mansoni z-protein (S1r protein) 0.0046 0.008 0.0125
Echinococcus granulosus regulator of G protein signaling 3 0.0046 0.008 0.0121
Echinococcus multilocularis microtubule associated protein 2 0.2238 0.6377 0.6376
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0126 0.0219
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0111 0.0266 0.0474
Entamoeba histolytica hypothetical protein 0.0046 0.008 0.0136
Echinococcus multilocularis beta adrenergic receptor kinase 0.0047 0.0082 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0104 0.018
Echinococcus granulosus intermediate filament protein 0.0087 0.0196 0.0304
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.0153 0.0272
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0045 0.0072
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0004 0.0006
Schistosoma mansoni RAR-like nuclear receptor 0.0071 0.0151 0.0237
Echinococcus granulosus neuropeptide s receptor 0.0997 0.2811 0.4406
Trypanosoma cruzi target of rapamycin kinase 3 0.0078 0.017 0.0299
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.0012 0.0062
Leishmania major beta tubulin 0.1945 0.5535 1
Brugia malayi intermediate filament protein 0.0087 0.0196 0.0351
Giardia lamblia Gamma tubulin 0.1074 0.3032 0.5475
Trypanosoma cruzi tubulin delta chain 0.0652 0.1819 0.3282
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0046 0.008 0.0136
Entamoeba histolytica hypothetical protein 0.019 0.0494 0.0886
Echinococcus multilocularis thyroid hormone receptor alpha 0.0071 0.0151 0.0149
Brugia malayi MH1 domain containing protein 0.0043 0.0071 0.0124
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Trichomonas vaginalis guanylate cyclase, putative 0.0055 0.0104 0.018
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0105
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0097 0.0227 0.0356
Onchocerca volvulus Putative organic anion transporter 0.0091 0.0209 0.0985
Schistosoma mansoni jun-related protein 0.0214 0.0562 0.0881
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0078 0.017 0.0299
Toxoplasma gondii endonuclease IV APN 0.0081 0.0181 0.0319
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0259 0.069 0.5319
Loa Loa (eye worm) hypothetical protein 0.0096 0.0223 0.04
Giardia lamblia GTOR 0.0097 0.0227 0.0402
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0074 0.0129
Onchocerca volvulus Protein ultraspiracle homolog 0.0071 0.0151 0.071
Trichomonas vaginalis adenylate cyclase, putative 0.0055 0.0104 0.018
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0074 0.0126
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0111 0.0266 0.0474
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0097 0.0227 0.0352
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.026 0.0461
Echinococcus granulosus expressed conserved protein 0.0199 0.0518 0.0808
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0055 0.0104 0.018
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.0012 0.0062
Onchocerca volvulus 0.0087 0.0196 0.0927
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Schistosoma mansoni rab6-interacting 0.0171 0.0438 0.0686
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0062 0.0105
Echinococcus granulosus FTZ F1 alpha 0.0071 0.0151 0.0233
Schistosoma mansoni Smad4 0.0019 0.0002 0.0004
Echinococcus multilocularis regulator of G protein signaling 7 0.0046 0.008 0.0077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0049 0.008
Schistosoma mansoni Smad4 0.0043 0.0071 0.0111
Schistosoma mansoni hypothetical protein 0.0052 0.0097 0.0153
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0013 0.0068
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0064 0.013 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0071 0.0151 0.027
Echinococcus granulosus Polycystic kidney disease protein 0.0171 0.0438 0.0683
Trypanosoma brucei trypanothione reductase 0.0102 0.024 0.0426
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0035 0.0049 0.0084
Brugia malayi nuclear receptor NHR-67 0.0031 0.0036 0.006
Schistosoma mansoni ap endonuclease 0.002 0.0004 0.0007
Mycobacterium leprae cell division protein FtsZ 0.0469 0.1294 1
Giardia lamblia Delta tubulin 0.0469 0.1294 0.2332
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0259 0.069 0.5304
Brugia malayi jmjC domain containing protein 0.0064 0.013 0.0231
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0062 0.0098
Brugia malayi hypothetical protein 0.0091 0.0209 0.0373
Echinococcus granulosus sterol regulatory element binding protein 0.0091 0.0208 0.0322
Trypanosoma brucei PAB1-binding protein , putative 0.0109 0.026 0.0461
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0041 0.0072
Loa Loa (eye worm) Smad1 0.0043 0.0071 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.0012 0.0062
Echinococcus multilocularis tubulin alpha 3 chain 0.1406 0.3988 0.3986
Echinococcus granulosus beta-adrenergic receptor kinase 0.0047 0.0082 0.0126
Brugia malayi Smad1 0.0043 0.0071 0.0124
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.0012 0.0062
Onchocerca volvulus 0.0091 0.0209 0.0985
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0155 0.0273
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0013 0.0016
Schistosoma mansoni survival motor neuron protein 0.0052 0.0097 0.0153
Schistosoma mansoni regulator of G protein signaling 0.0046 0.008 0.0125
Echinococcus multilocularis expressed conserved protein 0.0199 0.0518 0.0515
Brugia malayi MH1 domain containing protein 0.0024 0.0016 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.026 0.0461
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Trichomonas vaginalis tubulin alpha chain, putative 0.0575 0.16 0.2885
Echinococcus granulosus Tubulin alpha 1 chain 0.1406 0.3988 0.6252
Echinococcus granulosus tubulin subunit beta 0.1945 0.5535 0.8679
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0081 0.0181 0.1341
Schistosoma mansoni alpha tubulin 0.1406 0.3988 0.6253
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0021 0.0006 0.0003
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0062 0.006
Loa Loa (eye worm) phosphofructokinase 0.0116 0.0282 0.0507
Loa Loa (eye worm) hypothetical protein 0.0211 0.0554 0.0999
Schistosoma mansoni rab6-interacting 0.0171 0.0438 0.0686
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0013 0.0011
Loa Loa (eye worm) RGS-3 protein 0.0046 0.008 0.0141
Schistosoma mansoni axis inhibition protein axin 0.0046 0.008 0.0125
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.0012 0.0062
Schistosoma mansoni multidrug resistance protein 0.0023 0.0013 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0223 0.0349
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0282 0.0501
Loa Loa (eye worm) hypothetical protein 0.0171 0.0438 0.0788
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0049 0.008
Echinococcus granulosus mitogen activated protein kinase 3 0.0111 0.0266 0.0414
Echinococcus multilocularis neuropeptide s receptor 0.0997 0.2811 0.281
Treponema pallidum cell division protein FtsZ 0.0469 0.1294 1
Echinococcus multilocularis tubulin alpha 3 chain 0.1406 0.3988 0.3986
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.0012 0.0062
Echinococcus multilocularis tubulin alpha chain 0.1406 0.3988 0.3986
Loa Loa (eye worm) raf kinase 0.0046 0.008 0.0142
Onchocerca volvulus 0.0091 0.0209 0.0985
Plasmodium falciparum thioredoxin reductase 0.0035 0.0049 0.008
Loa Loa (eye worm) agrin synaptic family protein 0.0062 0.0126 0.0225
Schistosoma mansoni DNA helicase recq1 0.0031 0.0036 0.0056
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0004 0.0002
Trichomonas vaginalis tubulin beta chain, putative 0.1406 0.3988 0.7202
Entamoeba histolytica tubulin alpha chain, putative 0.1406 0.3988 0.7202
Toxoplasma gondii thioredoxin reductase 0.0102 0.024 0.0426
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0132 0.0991
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.0012 0.0062
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0013 0.0017
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0097 0.0227 0.0402
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0046 0.008 0.0121
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) alpha-tubulin 0.1406 0.3988 0.7204
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0031 0.0036 0.0033
Echinococcus multilocularis tubulin alpha 0.1044 0.2947 0.2945
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0031 0.0036 0.0033
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.0012 0.0062
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0097 0.0227 0.0402
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.004 0.0062 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0002
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0037 0.006
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Echinococcus granulosus mitogen activated protein kinase 0.0111 0.0266 0.0414
Echinococcus multilocularis sterol regulatory element binding protein 0.0091 0.0208 0.0205
Onchocerca volvulus 0.0091 0.0209 0.0985
Echinococcus multilocularis CREB binding protein 0.015 0.0379 0.0376
Echinococcus multilocularis smad 0.0043 0.0071 0.0069
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.0012 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.017 0.0299
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.0012 0.0062
Brugia malayi steroid hormone receptor 0.0071 0.0151 0.0268
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0151 0.0268
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0013 0.0036
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0097 0.0227 0.0402
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0023 0.0013 0.0014
Entamoeba histolytica tubulin alpha-1 chain 0.1406 0.3988 0.7202
Echinococcus multilocularis agrin 0.0062 0.0126 0.0123
Loa Loa (eye worm) nuclear factor I 0.0024 0.0016 0.0026
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0041 0.0066
Echinococcus granulosus Niemann Pick C1 protein 0.0302 0.0815 0.1275
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0182 0.0282
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0013 0.001
Onchocerca volvulus Huntingtin homolog 0.0384 0.1051 0.5011
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.0012 0.0062
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0055 0.0104 0.5402
Plasmodium falciparum tubulin gamma chain 0.1074 0.3032 0.5475
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0082 0.0129
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0053
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0081 0.0141
Echinococcus multilocularis protein dispatched 1 0.0104 0.0245 0.0242
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0062 0.0105
Brugia malayi Doublecortin family protein 0.0171 0.0438 0.0787
Brugia malayi hypothetical protein 0.0046 0.008 0.014
Schistosoma mansoni smad 0.0019 0.0002 0.0004
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0013 0.0011
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0049 0.0343
Brugia malayi Tubulin gamma chain 0.1074 0.3032 0.5476
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0132 0.0207
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0013 0.0016
Plasmodium vivax thioredoxin reductase, putative 0.0102 0.024 0.0426
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0033 0.0041 0.0066
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.0153 0.0268
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0021 0.003
Brugia malayi ecdysone receptor 0.0031 0.0036 0.006
Echinococcus granulosus tubulin beta 4A class IVa 0.1945 0.5535 0.8679
Schistosoma mansoni tubulin subunit alpha 0.1406 0.3988 0.6253
Schistosoma mansoni smad 0.0043 0.0071 0.0111
Brugia malayi hypothetical protein 0.0091 0.0209 0.0373
Loa Loa (eye worm) hypothetical protein 0.0091 0.0209 0.0374
Brugia malayi sodium-independent organic anion transporter family protein 0.0091 0.0209 0.0373
Giardia lamblia Beta tubulin 0.1945 0.5535 1
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0181 0.0319
Brugia malayi hypothetical protein 0.007 0.0149 0.0265
Echinococcus granulosus mothers against decapentaplegic 5 0.0043 0.0071 0.0107
Brugia malayi A-kinase anchor protein 10, precursor 0.0046 0.008 0.014
Loa Loa (eye worm) BEN-1 protein 0.1945 0.5535 1
Loa Loa (eye worm) thioredoxin reductase 0.0102 0.024 0.0432
Trichomonas vaginalis tubulin, putative 0.0575 0.16 0.2885
Toxoplasma gondii histone lysine methyltransferase SET1 0.0178 0.0458 0.0819
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0002
Echinococcus granulosus tumor protein p63 0.1469 0.4168 0.6535
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0266 0.0474
Loa Loa (eye worm) hypothetical protein 0.0082 0.0182 0.0327
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Echinococcus granulosus tubulin alpha 3 chain 0.1406 0.3988 0.6252
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0037 0.006
Trichomonas vaginalis mercuric reductase, putative 0.0035 0.0049 0.008
Echinococcus granulosus beta tubulin 0.1945 0.5535 0.8679
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0207 0.0321
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0013 0.0017
Echinococcus multilocularis follistatin 0.0062 0.0126 0.0123
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0013 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0002
Echinococcus multilocularis Tubulin beta 2C chain 0.1945 0.5535 0.5534
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.004 0.0062 0.006
Onchocerca volvulus Bile acid receptor homolog 0.0071 0.0151 0.071
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0045 0.0311
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0023 0.0013 0.0016
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0145 0.026
Echinococcus multilocularis beta tubulin 0.1945 0.5535 0.5534
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.0012 0.0062
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0062 0.0126 0.0223
Schistosoma mansoni cpg binding protein 0.009 0.0205 0.0322
Trichomonas vaginalis tubulin beta chain, putative 0.1406 0.3988 0.7202
Schistosoma mansoni agrin 0.0062 0.0126 0.0197
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.011
Leishmania major beta tubulin 0.1945 0.5535 1
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0013 0.0068
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0657 0.1834 0.3312
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0055 0.0104 0.018
Schistosoma mansoni CREB-binding protein 2 0.0219 0.0577 0.0904
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0081 0.0181 0.0323
Trichomonas vaginalis tubulin alpha chain, putative 0.1945 0.5535 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0021 0.0029
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0062 0.0105
Loa Loa (eye worm) glutathione reductase 0.0102 0.024 0.0432
Mycobacterium leprae putative cytochrome p450 0.0023 0.0012 0.003
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0071 0.0151 0.0233
Echinococcus granulosus expressed protein 0.0803 0.2255 0.3534
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0035 0.0049 0.008
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Trichomonas vaginalis tubulin beta chain, putative 0.1945 0.5535 1
Schistosoma mansoni Smad4 0.0019 0.0002 0.0004
Echinococcus multilocularis tubulin alpha 1C chain 0.1406 0.3988 0.3986
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0208 0.0368
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0091 0.0208 0.0373
Echinococcus granulosus agrin 0.0062 0.0126 0.0193
Loa Loa (eye worm) hypothetical protein 0.0062 0.0126 0.0225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0155 0.0273
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0037 0.006
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0141
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0141
Leishmania major beta tubulin 0.1945 0.5535 1
Schistosoma mansoni cpg binding protein 0.0095 0.022 0.0345
Loa Loa (eye worm) hypothetical protein 0.0171 0.0438 0.0788
Echinococcus multilocularis protein patched 0.0091 0.0208 0.0205
Trichomonas vaginalis tubulin, putative 0.0575 0.16 0.2885
Mycobacterium tuberculosis Probable oxidoreductase 0.0259 0.069 0.5319
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Brugia malayi tubulin alpha-2 chain 0.1406 0.3988 0.7204
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0046 0.008 0.0077
Mycobacterium leprae Possible regulatory protein 0.0055 0.0104 0.0741
Leishmania major beta tubulin 0.1945 0.5535 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0002
Onchocerca volvulus 0.0171 0.0438 0.208
Echinococcus granulosus peroxisome assembly protein 26 0.1406 0.3988 0.6252
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0037 0.006
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0091 0.0209 0.0323
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0098 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.008 0.0136
Schistosoma mansoni tubulin subunit beta 0.0469 0.1294 0.2029
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0266 0.0474
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0223 0.022
Brugia malayi Tubulin alpha-2 chain 0.1406 0.3988 0.7204
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0031 0.0036 0.0062
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Leishmania major beta tubulin 0.1945 0.5535 1
Loa Loa (eye worm) hypothetical protein 0.0831 0.2335 0.4217
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0037 0.1447
Echinococcus granulosus Tubulin beta 2C chain 0.1945 0.5535 0.8679
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0021
Mycobacterium ulcerans hypothetical protein 0.0021 0.0009 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0082 0.0129
Plasmodium falciparum thioredoxin reductase 0.0102 0.024 0.0426
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0036 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0135 0.0236
Brugia malayi 6-phosphofructokinase 0.0117 0.0283 0.0506
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0141
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0132 0.013
Echinococcus multilocularis Tubulin beta 2C chain 0.1945 0.5535 0.5534
Echinococcus granulosus regulator of G protein signaling 7 0.0046 0.008 0.0121
Entamoeba histolytica P-glycoprotein-1 0.0023 0.0013 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0041 0.0066
Schistosoma mansoni lipoxygenase 0.0681 0.1904 0.2985
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0026
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0055 0.0104 0.018
Echinococcus multilocularis ecdysone induced protein 78C 0.0071 0.0151 0.0149
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Loa Loa (eye worm) hypothetical protein 0.0071 0.0151 0.027
Entamoeba histolytica hypothetical protein 0.0046 0.008 0.0136
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0233 0.0616 0.4741
Schistosoma mansoni thyroid hormone receptor 0.0071 0.0151 0.0237
Loa Loa (eye worm) hypothetical protein 0.0257 0.0684 0.1234
Trypanosoma brucei epsilon tubulin 0.1073 0.3031 0.5472
Loa Loa (eye worm) tubulin beta-2A chain 0.1945 0.5535 1
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0023 0.0013 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.0012 0.0062
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0037 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0266 0.0474
Trypanosoma cruzi tubulin gamma chain 0.1074 0.3032 0.5475
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0259 0.069 0.5319
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0055 0.0104 0.0159
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0062 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0071 0.0151 0.0268
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0067 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0098 0.017
Entamoeba histolytica hypothetical protein 0.0023 0.0013 0.0016
Echinococcus multilocularis geminin 0.0897 0.2524 0.2522
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0151 0.0149
Echinococcus granulosus bloom syndrome protein 0.0044 0.0074 0.0112
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0036 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.0012 0.0062
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0071 0.0151 0.027
Schistosoma mansoni tubulin subunit beta 0.1945 0.5535 0.8679
Mycobacterium ulcerans cell division protein FtsZ 0.0469 0.1294 1
Echinococcus granulosus tubulin alpha chain 0.1406 0.3988 0.6252
Schistosoma mansoni tubulin subunit epsilon 0.1073 0.3031 0.4753
Leishmania major beta tubulin 0.1945 0.5535 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0243 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0002
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0111 0.0266 0.0474
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.0012 0.0062
Entamoeba histolytica hypothetical protein 0.0046 0.008 0.0136
Toxoplasma gondii cytochrome p450 superfamily protein 0.0023 0.0012 0.0014
Leishmania major cytochrome p450-like protein 0.0069 0.0147 0.0257
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0132 0.0991
Echinococcus multilocularis nuclear receptor nhr 48 0.0031 0.0036 0.0033
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0182 0.0325
Brugia malayi CXXC zinc finger family protein 0.009 0.0205 0.0367
Trypanosoma brucei beta tubulin 0.1945 0.5535 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0171 0.0438 0.0435
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0194 0.0505 0.0792
Trypanosoma cruzi MFS transporter, putative 0.0091 0.0209 0.0369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0041 0.0066
Schistosoma mansoni hypothetical protein 0.0171 0.0438 0.0686
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0013 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0041 0.0066
Brugia malayi jmjC domain containing protein 0.0069 0.0145 0.0258
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0044 0.0071
Echinococcus granulosus Tubulin alpha 1 chain 0.1406 0.3988 0.6252
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0031 0.0036 0.0062
Trypanosoma brucei zeta tubulin, putative 0.0774 0.2172 0.392
Trypanosoma brucei beta tubulin 0.1044 0.2947 0.5321
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0006 0.0002
Schistosoma mansoni hypothetical protein 0.0275 0.0737 0.1156
Brugia malayi hypothetical protein 0.004 0.0062 0.0108
Echinococcus multilocularis regulator of G protein signaling 3 0.0046 0.008 0.0077
Trichomonas vaginalis tubulin, putative 0.1945 0.5535 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0035 0.0049 0.0343
Giardia lamblia Kinase, CMGC MAPK 0.0111 0.0266 0.0474
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0013 0.0016
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0013 0.0016
Brugia malayi Cytochrome P450 family protein 0.0069 0.0147 0.0261
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.0012 0.0062
Onchocerca volvulus 0.0031 0.0036 0.0158
Toxoplasma gondii beta-tubulin, putative 0.1945 0.5535 1
Brugia malayi nuclear receptor NHR-88 0.0031 0.0036 0.006
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0351 0.2688
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.011
Brugia malayi MH1 domain containing protein 0.0043 0.0071 0.0124
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0071 0.0151 0.0233
Echinococcus multilocularis mothers against decapentaplegic 5 0.0043 0.0071 0.0069
Schistosoma mansoni hypothetical protein 0.0897 0.2524 0.3958
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0062 0.0105
Echinococcus granulosus tubulin alpha 1C chain 0.1406 0.3988 0.6252
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.0282 0.0501
Loa Loa (eye worm) CYP4Cod1 0.0069 0.0147 0.0263
Schistosoma mansoni smad1 5 8 and 0.0043 0.0071 0.0111
Loa Loa (eye worm) tubulin alpha 2 0.0937 0.2641 0.477
Echinococcus multilocularis regulator of G protein signaling 7 0.0046 0.008 0.0077
Entamoeba histolytica P-glycoprotein 5, putative 0.0023 0.0013 0.0016
Echinococcus granulosus tubulin alpha chain 0.1406 0.3988 0.6252
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0035 0.0049 0.0343
Schistosoma mansoni axis inhibition protein axin 0.0046 0.008 0.0125
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Echinococcus granulosus raf serine:threonine protein kinase 0.0046 0.008 0.0121
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0263 0.0704 0.0701
Schistosoma mansoni intermediate filament proteins 0.0087 0.0196 0.0308
Loa Loa (eye worm) hypothetical protein 0.0384 0.1051 0.1897
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0097 0.0227 0.0402
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0071 0.0151 0.027
Brugia malayi follicle stimulating hormone receptor 0.0261 0.0698 0.1257
Onchocerca volvulus 0.0052 0.0097 0.0454
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0031 0.0036 0.0057
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0071 0.0151 0.0233
Entamoeba histolytica P-glycoprotein-2, putative 0.0023 0.0013 0.0016
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0043 0.0071 0.0069
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0151 0.0268
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0036 0.006
Loa Loa (eye worm) MH1 domain-containing protein 0.0043 0.0071 0.0126
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0009 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.0012 0.0062
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0036 0.0052
Loa Loa (eye worm) PXA domain-containing protein 0.0046 0.008 0.0141
Mycobacterium ulcerans putative regulatory protein 0.0155 0.0393 0.3017
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0091 0.0209 0.0374
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0233 0.0616 0.4741
Trichomonas vaginalis abcb9, putative 0.0023 0.0013 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0114 0.0199
Entamoeba histolytica P-glyco protein 6, putative 0.0023 0.0013 0.0016
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0013 0.0017
Schistosoma mansoni coup transcription factor 0.0071 0.0151 0.0237
Plasmodium falciparum tubulin beta chain 0.1945 0.5535 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0113 0.0196
Brugia malayi hypothetical protein 0.0171 0.0438 0.0787
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0055 0.0104 0.018
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0012 0.0016
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0036 0.006
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0071 0.0151 0.0268
Schistosoma mansoni polycystin 1-related 0.0171 0.0438 0.0686
Echinococcus multilocularis tubulin subunit TubB 0.1406 0.3988 0.3986
Plasmodium vivax delta tubulin, putative 0.0469 0.1294 0.2332
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.019 0.0494 0.0492
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.0012 0.0062
Echinococcus multilocularis mitogen activated protein kinase 0.0111 0.0266 0.0264
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0045 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0002
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0012 0.0014
Leishmania major beta tubulin 0.1945 0.5535 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0031 0.0036 0.0033
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.0012 0.0062
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0045 0.0042
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0036 0.006
Loa Loa (eye worm) hypothetical protein 0.0081 0.0181 0.0324
Entamoeba histolytica tubulin family protein 0.1945 0.5535 1
Brugia malayi Cytochrome P450 family protein 0.0023 0.0012 0.0018
Brugia malayi nuclear hormone receptor 0.0031 0.0036 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0037 0.006
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.011
Echinococcus multilocularis Tubulin alpha 1 chain 0.1406 0.3988 0.3986
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0151 0.0233
Leishmania major protein kinase, putative 0.0056 0.0107 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.0227 0.0402
Echinococcus multilocularis tubulin epsilon chain 0.1073 0.3031 0.3029
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0045 0.0072
Echinococcus multilocularis Niemann Pick C1 protein 0.0302 0.0815 0.0813
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0022 0.0035
Schistosoma mansoni transcription factor LCR-F1 0.019 0.0494 0.0775
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0013 0.0016
Brugia malayi regulator of G-protein signaling rgs-7 0.0046 0.008 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0113 0.0196
Echinococcus granulosus tubulin subunit TubB 0.1406 0.3988 0.6252
Brugia malayi multidrug resistance protein 3 0.0023 0.0013 0.002
Echinococcus granulosus CREB binding protein 0.0036 0.005 0.0075
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0035 0.0049 0.0076
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0111 0.0266 0.0474
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0266 0.0474
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0223 0.0349
Echinococcus granulosus lamin dm0 0.0087 0.0196 0.0304
Echinococcus multilocularis expressed protein 0.0062 0.0126 0.0123
Chlamydia trachomatis endonuclease IV 0.0081 0.0181 1
Leishmania major beta tubulin 0.1945 0.5535 1
Echinococcus multilocularis FTZ F1 alpha 0.0071 0.0151 0.0149
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0035 0.0049 0.0343
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.008 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0071 0.0151 0.027
Echinococcus granulosus tubulin alpha chain 0.1406 0.3988 0.6252
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.011
Echinococcus granulosus axis inhibition protein axin 0.0046 0.008 0.0121
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0031 0.0036 0.0052
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0223 0.0394
Brugia malayi PAS domain containing protein 0.021 0.055 0.099
Schistosoma mansoni regulator of G protein signaling 0.0046 0.008 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0022 0.0032
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.0153 0.0268
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0033 0.0041 0.006
Schistosoma mansoni patched 1 0.0091 0.0208 0.0326
Echinococcus granulosus microtubule associated protein 2 0.2238 0.6377 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Brugia malayi Tubulin beta chain 0.0575 0.16 0.2888
Schistosoma mansoni hypothetical protein 0.0087 0.0198 0.0311
Entamoeba histolytica tubulin gamma chain 0.1074 0.3032 0.5475
Brugia malayi MAP kinase sur-1 0.0111 0.0266 0.0477
Loa Loa (eye worm) hypothetical protein 0.0071 0.0151 0.027
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0071 0.0151 0.027
Plasmodium vivax SET domain protein, putative 0.0096 0.0223 0.0394
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0022 0.0035
Brugia malayi MH2 domain containing protein 0.0043 0.0071 0.0124
Loa Loa (eye worm) hypothetical protein 0.1406 0.3988 0.7204
Echinococcus multilocularis Niemann Pick C1 protein 0.0211 0.0554 0.0552
Echinococcus multilocularis regulator of G protein signaling 3 0.0046 0.008 0.0077
Echinococcus granulosus nuclear receptor nhr 48 0.0031 0.0036 0.0052
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.0012 0.0062
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0066 0.01
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0031 0.0036 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0071 0.0151 0.027
Onchocerca volvulus 0.0747 0.2094 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0469 0.1294 0.2332
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.0012 0.0062
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0181 0.0319
Echinococcus granulosus lipoxygenase domain containing protein 0.0171 0.0438 0.0683
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0071 0.0151 0.027
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0045 0.0076
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0035 0.0049 0.0046
Leishmania major hypothetical protein, conserved 0.0109 0.026 0.0461
Schistosoma mansoni zinc finger protein 0.0031 0.0036 0.0056
Schistosoma mansoni organic anion transporter 0.0091 0.0209 0.0327
Brugia malayi hypothetical protein 0.004 0.0062 0.0108
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.0153 0.0236
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0097 0.0227 0.0402
Echinococcus granulosus Tubulin alpha 1 chain 0.1406 0.3988 0.6252
Brugia malayi Regulator of G protein signaling domain containing protein 0.0046 0.008 0.014
Schistosoma mansoni hypothetical protein 0.0087 0.0198 0.0311
Leishmania major zeta tubulin, putative 0.0774 0.2172 0.392
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0035 0.0049 0.008
Brugia malayi orphan nuclear receptor NR2E1 0.0031 0.0036 0.006
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0013 0.0016
Toxoplasma gondii transporter, major facilitator family protein 0.0091 0.0209 0.0369
Schistosoma mansoni tubulin subunit beta 0.1945 0.5535 0.8679
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.1044 0.2947 0.5321
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0047 0.0082 0.0147
Brugia malayi Tubulin alpha-2 chain 0.1406 0.3988 0.7204
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0126 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0071 0.0151 0.0268
Brugia malayi phosphofructokinase 0.0116 0.0282 0.0505
Trichomonas vaginalis tubulin beta chain, putative 0.0575 0.16 0.2885
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0064 0.013 0.0201
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0023 0.0013 0.0016
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0035 0.0049 0.008
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0074 0.0126
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0147 0.0257
Echinococcus multilocularis lipoxygenase domain containing protein 0.0171 0.0438 0.0435
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0102 0.024 0.1828
Entamoeba histolytica tubulin family protein 0.1945 0.5535 1
Echinococcus granulosus RUN 0.0171 0.0438 0.0683
Brugia malayi Tubulin alpha chain 0.0469 0.1294 0.2334
Loa Loa (eye worm) hypoxia-induced factor 1 0.065 0.1814 0.3275
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0047 0.0082 0.0147
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0044 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0151 0.0268
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0033 0.0041 0.0066
Trypanosoma brucei beta tubulin 0.1945 0.5535 1
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0351 0.2665
Mycobacterium tuberculosis Probable reductase 0.0233 0.0616 0.4741
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0071 0.0151 0.0237
Brugia malayi ecdysteroid receptor 0.0071 0.0151 0.0268
Loa Loa (eye worm) tubulin alpha chain 0.1406 0.3988 0.7204
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0062 0.0126 0.0225
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0004 0.0004
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0215 0.0564 0.0884
Giardia lamblia Alpha-tubulin 0.1406 0.3988 0.7202
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0082 0.0129
Trypanosoma brucei beta tubulin 0.1945 0.5535 1
Trypanosoma brucei tubulin delta chain 0.0652 0.1819 0.3282
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0071 0.0151 0.0268
Schistosoma mansoni regulator of G protein signaling 0.0046 0.008 0.0125
Echinococcus granulosus tubulin alpha chain 0.1406 0.3988 0.6252
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0071 0.0151 0.0237
Trichomonas vaginalis tubulin beta chain, putative 0.1406 0.3988 0.7202
Onchocerca volvulus 0.0171 0.0438 0.208
Loa Loa (eye worm) BEN-1 protein 0.1945 0.5535 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0013 0.0017
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0013 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0071 0.0151 0.0268
Schistosoma mansoni smdr2 0.0023 0.0013 0.0021
Trypanosoma brucei epsilon tubulin 0.1073 0.3031 0.5472
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0132 0.0991
Trypanosoma brucei epsilon tubulin 0.1044 0.2947 0.5321
Loa Loa (eye worm) hypothetical protein 0.0215 0.0565 0.1018
Plasmodium vivax tubulin gamma chain, putative 0.1074 0.3032 0.5475
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0062 0.0108
Echinococcus granulosus follistatin 0.0062 0.0126 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0077 0.017 0.0299
Onchocerca volvulus Putative organic anion transporter 0.0091 0.0209 0.0985
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0107 0.0185
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0062 0.0108
Loa Loa (eye worm) pax transcription factor protein 2 0.0261 0.0698 0.1258
Brugia malayi ABC transporter family protein 0.0023 0.0013 0.002
Schistosoma mansoni cellular tumor antigen P53 0.0215 0.0565 0.0886
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0223 0.0349
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0013 0.0016
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0071 0.0151 0.0149
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0069 0.0147 0.1103
Leishmania major p-glycoprotein 0.0023 0.0013 0.0016
Trichomonas vaginalis tubulin, putative 0.0498 0.1379 0.2486
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.011
Onchocerca volvulus 0.0207 0.0541 0.2575
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0186 0.0328
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0031 0.0036 0.0052
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0031 0.0036 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0104 0.018
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0037 0.1447
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0469 0.1294 0.2332
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.008 0.0136
Leishmania major beta tubulin 0.1945 0.5535 1
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0062 0.0094
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Echinococcus multilocularis tubulin gamma 1 chain 0.1074 0.3032 0.303
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0055 0.0104 0.018
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0013 0.0068
Plasmodium vivax tubulin alpha chain, putative 0.1406 0.3988 0.7202
Onchocerca volvulus Huntingtin homolog 0.0384 0.1051 0.5011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0049 0.008
Plasmodium falciparum multidrug resistance protein 1 0.0023 0.0013 0.0016
Loa Loa (eye worm) tubulin alpha-3 chain 0.0831 0.2335 0.4217
Loa Loa (eye worm) hypothetical protein 0.0111 0.0266 0.0479
Loa Loa (eye worm) DR-78 0.0031 0.0036 0.0062
Loa Loa (eye worm) hypothetical protein 0.004 0.0063 0.0111
Schistosoma mansoni tubulin subunit alpha 0.1406 0.3988 0.6253
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.008 0.0136
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) tubulin beta chain 0.0469 0.1294 0.2336
Brugia malayi sodium-independent organic anion transporter family protein 0.0091 0.0209 0.0373
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0023 0.0012 0.0062
Entamoeba histolytica hypothetical protein 0.019 0.0494 0.0886
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0056 0.0107 0.0185
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0147 0.0263
Schistosoma mansoni alpha tubulin 0.1406 0.3988 0.6253
Echinococcus multilocularis 0.0023 0.0012 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Loa Loa (eye worm) hypothetical protein 0.0109 0.026 0.0467
Echinococcus multilocularis Smad4 0.0043 0.0071 0.0069
Schistosoma mansoni lipoxygenase 0.0374 0.1021 0.1601
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0002 0.0002
Onchocerca volvulus 0.009 0.0205 0.0971
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0071 0.0151 0.0268
Entamoeba histolytica hypothetical protein 0.019 0.0494 0.0886
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0055 0.0104 0.0185
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0021 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.0012 0.0062
Leishmania major alpha tubulin 0.1406 0.3988 0.7202
Echinococcus granulosus Tubulin beta 2C chain 0.1945 0.5535 0.8679
Leishmania major beta tubulin 0.1945 0.5535 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0031 0.0036 0.0052
Onchocerca volvulus 0.0082 0.0182 0.086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0037 0.006
Trichomonas vaginalis glutathione reductase, putative 0.0035 0.0049 0.008
Brugia malayi PXA domain containing protein 0.0046 0.008 0.014
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0151 0.0233
Echinococcus multilocularis mitogen activated protein kinase 3 0.0111 0.0266 0.0264
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0037 0.0054
Echinococcus multilocularis Tubulin alpha 1 chain 0.1406 0.3988 0.3986
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0035 0.0049 0.008
Loa Loa (eye worm) cytochrome P450 0.0023 0.0012 0.002
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0013 0.0017
Echinococcus granulosus tubulin alpha 0.1044 0.2947 0.4619
Schistosoma mansoni regulator of G protein signaling 0.0047 0.0083 0.013
Trichomonas vaginalis abcb9, putative 0.0023 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Loa Loa (eye worm) hypothetical protein 0.0071 0.0151 0.027
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0012 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0155 0.0273
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.0684 0.107
Brugia malayi Cytochrome P450 family protein 0.0069 0.0147 0.0261
Brugia malayi conserved hypotetical protein 0.0031 0.0036 0.006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0145 0.0228
Loa Loa (eye worm) hypothetical protein 0.0062 0.0126 0.0225
Schistosoma mansoni DNA helicase recq5 0.0031 0.0036 0.0056
Schistosoma mansoni hypothetical protein 0.0087 0.0198 0.0311
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.0012 0.0062
Brugia malayi nuclear hormone receptor family member nhr-6 0.0031 0.0036 0.006
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0132 0.0231
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0219 0.0577 0.0904
Schistosoma mansoni ap endonuclease 0.002 0.0004 0.0007
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0081 0.0181 0.1368
Schistosoma mansoni tubulin subunit alpha 0.0469 0.1294 0.2029
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0055 0.0104 0.0101
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0012 0.002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0004 0.0003
Trichomonas vaginalis tubulin alpha chain, putative 0.0575 0.16 0.2885
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0021 0.0019
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.019 0.0494 0.0772
Treponema pallidum fructose-bisphosphate aldolase 0.0288 0.0774 0.5969
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0049 0.008
Mycobacterium ulcerans endonuclease IV 0.0081 0.0181 0.1368
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0116 0.0282 0.2126
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0177 0.0174
Schistosoma mansoni loxhd1 0.0171 0.0438 0.0686
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0153 0.0268
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0023 0.0012 0.0014
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0223 0.022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Onchocerca volvulus 0.0261 0.0698 0.3323
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0013 0.0016
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0071 0.0151 0.0237
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0036 0.0056
Leishmania major trypanothione reductase 0.0102 0.024 0.0426
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0013 0.0068
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0045 0.0072
Plasmodium falciparum tubulin delta chain, putative 0.0469 0.1294 0.2332
Echinococcus granulosus beta tubulin 0.1945 0.5535 0.8679
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0104 0.018
Loa Loa (eye worm) hypothetical protein 0.0384 0.1051 0.1897
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0045 0.0042
Echinococcus granulosus 6 phosphofructokinase 0.0116 0.0282 0.0438
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.0774 0.1392
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0045 0.0072
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0097 0.0227 0.0406
Schistosoma mansoni tubulin subunit alpha 0.1406 0.3988 0.6253
Brugia malayi MH1 domain containing protein 0.0024 0.0016 0.0024
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0049 0.008
Echinococcus multilocularis regulator of G protein signaling 0.0046 0.008 0.0077
Schistosoma mansoni thyroid hormone receptor 0.0071 0.0151 0.0237
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0147 0.0263
Echinococcus multilocularis lamin dm0 0.0087 0.0196 0.0194
Schistosoma mansoni nuclear receptor nhr-48 0.0031 0.0036 0.0056
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0049 0.0087 0.0133
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.0282 0.0501
Loa Loa (eye worm) hypothetical protein 0.0937 0.2641 0.477
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0098 0.0169
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0062 0.0126 0.0223
Giardia lamblia Sgs1 DNA helicase, putative 0.0031 0.0036 0.0057
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0498 0.1378 0.2483
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0036 0.0158
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0071 0.0151 0.0149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0114 0.0199
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.0012 0.0062
Toxoplasma gondii protease inhibitor PI2 0.0062 0.0126 0.0219
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0036 0.0057
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0153 0.0268
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.0012 0.0062
Brugia malayi photoreceptor-specific nuclear receptor 0.0071 0.0151 0.0268
Brugia malayi cytochrome P450 0.0023 0.0012 0.0018
Schistosoma mansoni tubulin subunit beta 0.1945 0.5535 0.8679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0098 0.0169
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0266 0.0418
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Schistosoma mansoni steroid hormone receptor ad4bp 0.0071 0.0151 0.0237
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Onchocerca volvulus 0.0215 0.0565 0.2689
Schistosoma mansoni single-minded 0.021 0.055 0.0863
Onchocerca volvulus 0.0087 0.0196 0.0927
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0067 0.0065
Brugia malayi hypothetical protein 0.019 0.0494 0.0889
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0111 0.0266 0.0474
Echinococcus multilocularis CREB binding protein 0.0036 0.005 0.0048
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0233 0.0616 0.4724
Leishmania major beta tubulin 0.1945 0.5535 1
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0013 0.0016
Trypanosoma brucei zeta tubulin 0.0774 0.2172 0.392
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0062 0.0108
Leishmania major beta tubulin 0.1945 0.5535 1
Loa Loa (eye worm) histone methyltransferase 0.0031 0.0037 0.0064
Trichomonas vaginalis tubulin epsilon chain, putative 0.0469 0.1294 0.2332
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0151 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.008 0.0136
Schistosoma mansoni follistatin 0.0062 0.0126 0.0197
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0177 0.0273
Schistosoma mansoni lamin 0.0087 0.0196 0.0308
Brugia malayi hypothetical protein 0.0171 0.0438 0.0787
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0037 0.006
Onchocerca volvulus 0.0071 0.0151 0.071
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0182 0.018
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0011 0.0013
Loa Loa (eye worm) beta-tubulin 0.1945 0.5535 1
Loa Loa (eye worm) CBP-B 0.0152 0.0384 0.0692
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0129 0.0225
Trichomonas vaginalis tubulin epsilon chain, putative 0.1406 0.3988 0.7202
Onchocerca volvulus Putative organic anion transporter 0.0091 0.0209 0.0985
Echinococcus multilocularis RUN 0.0171 0.0438 0.0435
Onchocerca volvulus 0.0062 0.0126 0.0589
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0091 0.0209 0.0206
Brugia malayi MH2 domain containing protein 0.0043 0.0071 0.0124
Plasmodium vivax tubulin epsilon chain, putative 0.1073 0.3031 0.5472
Schistosoma mansoni multidrug resistance protein 0.0023 0.0013 0.0021
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0036 0.0158
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0062
Echinococcus granulosus tubulin gamma 1 chain 0.1074 0.3032 0.4753
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0233 0.0616 0.4741
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0132 0.0207
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0681 0.1904 0.1902
Brugia malayi glutathione reductase 0.0102 0.024 0.043
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.0684 0.0682

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 55.3 uM Inhibition of human cloned MIF tautomerase activity expressed in Escherichia coli assessed as conversion of L-dopachrome methyl ester to indolecarboxylic acid methyl ester measured for 20 secs ChEMBL. 22088307

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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