Detailed information for compound 159850

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 150.135 | Formula: C7H6N2O2
  • H donors: 1 H acceptors: 3 LogP: 1.41 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc2c(n1)oc(n2)O
  • InChi: 1S/C7H6N2O2/c1-4-2-3-5-6(8-4)11-7(10)9-5/h2-3H,1H3,(H,9,10)
  • InChiKey: AJIPIXAYNVCKAL-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nitric oxide synthase 2, inducible Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0015 0.0021
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0039 0.0074
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0036 0.0055
Echinococcus granulosus single minded 2 0.0152 0.0395 0.0617
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0042 0.0081
Leishmania major cytochrome P450 reductase, putative 0.0029 0.0032 0.0052
Brugia malayi photoreceptor-specific nuclear receptor 0.0069 0.0151 0.0294
Entamoeba histolytica tubulin alpha chain, putative 0.133 0.3841 0.7545
Echinococcus granulosus peroxisome assembly protein 26 0.133 0.3841 0.6029
Loa Loa (eye worm) hypothetical protein 0.0087 0.0204 0.04
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0015 0.0026
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0067 0.0066
Loa Loa (eye worm) histone methyltransferase 0.0031 0.004 0.008
Echinococcus granulosus TGF beta signal transducer SmadC 0.0043 0.0074 0.0114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.005 0.0095
Trichomonas vaginalis tubulin epsilon chain, putative 0.1756 0.509 1
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0079 0.0152
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0039 0.0074
Onchocerca volvulus 0.0087 0.0204 0.0924
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0037 0.0069
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0228 0.0617 0.5016
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0039 0.0074
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0014 0.0025
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0063 0.0113
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0096 0.0229 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.01 0.0193
Echinococcus granulosus Regulator of G protein signaling 20 0.0045 0.0079 0.0121
Brugia malayi hypothetical protein 0.0251 0.0683 0.1339
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0075 0.0144
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Schistosoma mansoni cpg binding protein 0.0096 0.0228 0.0356
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0079 0.0121
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0061 0.0127 0.0247
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0069 0.0151 0.0235
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0014 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0042 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Loa Loa (eye worm) hypothetical protein 0.0109 0.0267 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.01 0.0194
Giardia lamblia Beta tubulin 0.1756 0.509 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0079 0.0152
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0616 0.1751 0.3439
Brugia malayi MH1 domain containing protein 0.0024 0.0018 0.0032
Trypanosoma brucei PAB1-binding protein , putative 0.0107 0.0261 0.051
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0015 0.0026
Onchocerca volvulus 0.0054 0.0105 0.0466
Schistosoma mansoni rab6-interacting 0.0165 0.0431 0.0675
Loa Loa (eye worm) alpha-tubulin 0.133 0.3841 0.7546
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0042 0.0081
Schistosoma mansoni tubulin subunit beta 0.1756 0.509 0.7991
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0039 0.0066
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0079 0.0077
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0014 0.007
Trypanosoma cruzi beta tubulin, putative 0.1756 0.509 1
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0266 0.0727 0.1139
Schistosoma mansoni hypothetical protein 0.0895 0.257 0.4033
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0105 0.0196
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0284 0.0556
Schistosoma mansoni tubulin subunit alpha 0.0436 0.1225 0.1921
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0035 0.005 0.0364
Trichomonas vaginalis sulfite reductase, putative 0.0032 0.0043 0.0081
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0069 0.0151 0.0294
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0659 0.1877 0.1876
Brugia malayi nuclear hormone receptor 0.0069 0.0151 0.0294
Schistosoma mansoni alpha tubulin 0.133 0.3841 0.6029
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0035 0.005 0.0364
Entamoeba histolytica P-glycoprotein-5 0.0023 0.0015 0.0026
Echinococcus multilocularis expressed conserved protein 0.0194 0.0517 0.0516
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0229 0.0447
Plasmodium vivax ataxin-2 like protein, putative 0.0107 0.0261 0.0502
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0036 0.0055
Brugia malayi MH2 domain containing protein 0.0019 0.0005 0.0006
Schistosoma mansoni single-minded 0.0206 0.0551 0.0864
Brugia malayi Tubulin alpha-2 chain 0.133 0.3841 0.7545
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0015 0.0026
Leishmania major p450 reductase, putative 0.0032 0.0043 0.0073
Loa Loa (eye worm) hypothetical protein 0.0061 0.0127 0.025
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0042 0.0081
Brugia malayi MH2 domain containing protein 0.0043 0.0074 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.01 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.01 0.0194
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0042 0.0064
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0153 0.0239
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0015 0.0026
Trichomonas vaginalis tubulin gamma chain, putative 0.0436 0.1225 0.2404
Brugia malayi ecdysone receptor 0.003 0.0036 0.0069
Schistosoma mansoni hypothetical protein 0.0859 0.2463 0.3866
Brugia malayi tailless protein 0.003 0.0036 0.0069
Brugia malayi FAD binding domain containing protein 0.0032 0.0043 0.0081
Onchocerca volvulus 0.009 0.021 0.0954
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0069 0.0151 0.015
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0284 0.0558
Mycobacterium leprae cell division protein FtsZ 0.0436 0.1225 1
Echinococcus multilocularis geminin 0.0895 0.257 0.2569
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0006 0.0006
Echinococcus granulosus microtubule associated protein 2 0.2193 0.637 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.0267 0.0523
Echinococcus granulosus CREB binding protein 0.0034 0.0047 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0172 0.0334
Loa Loa (eye worm) FAD binding domain-containing protein 0.0032 0.0043 0.0084
Loa Loa (eye worm) multidrug resistance protein 3 0.0023 0.0015 0.0029
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.001 0.0016
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0042 0.0041
Brugia malayi jmjC domain containing protein 0.0062 0.0131 0.0255
Leishmania major beta tubulin 0.1756 0.509 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0133 0.1046
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.003 0.0045
Giardia lamblia GTOR 0.0096 0.0229 0.044
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0257 0.0701 0.1378
Loa Loa (eye worm) tubulin beta chain 0.1756 0.509 1
Brugia malayi SPARC precursor 0.0061 0.0127 0.0247
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0153 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0079 0.0152
Echinococcus multilocularis aryl hydrocarbon receptor 0.0054 0.0105 0.0104
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.133 0.3841 0.7545
Brugia malayi prostaglandin transporter 0.009 0.021 0.0411
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.003 0.0037 0.0035
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0284 0.0556
Toxoplasma gondii protease inhibitor PI2 0.0061 0.0127 0.0247
Brugia malayi beta-tubulin, identical 0.1756 0.509 1
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0032 0.0043 0.0081
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0039 0.0075
Leishmania major protein kinase, putative 0.0055 0.0108 0.0201
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0061 0.0127 0.0247
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0042 0.0064
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0124
Brugia malayi hypothetical protein 0.0069 0.015 0.0292
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0005 0.0003
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0089 0.0208 0.0409
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0009
Trypanosoma cruzi target of rapamycin kinase 3 0.0076 0.0172 0.0335
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0014 0.007
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0126
Echinococcus multilocularis lamin dm0 0.0085 0.0197 0.0196
Leishmania major beta tubulin 0.1756 0.509 1
Brugia malayi Cytochrome P450 family protein 0.0069 0.0149 0.029
Loa Loa (eye worm) hypothetical protein 0.0069 0.0151 0.0297
Trichomonas vaginalis tubulin, putative 0.0533 0.1509 0.2963
Echinococcus multilocularis tubulin alpha chain 0.133 0.3841 0.384
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0153 0.0299
Brugia malayi ABC transporter family protein 0.0023 0.0015 0.0026
Echinococcus multilocularis neuropeptide receptor A26 0.0975 0.2804 0.2803
Loa Loa (eye worm) hypothetical protein 0.0085 0.0197 0.0388
Leishmania major beta tubulin 0.1756 0.509 1
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0032 0.0043 0.0041
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0039 0.0063 0.0097
Loa Loa (eye worm) tubulin alpha chain 0.133 0.3841 0.7546
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0063 0.0097
Trypanosoma brucei tubulin delta chain 0.0616 0.1751 0.3439
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0075 0.0144
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0069 0.0151 0.0235
Brugia malayi regulator of G-protein signaling egl-10 0.0045 0.0079 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0157 0.0306
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0043 0.0074 0.0114
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0131 0.013
Brugia malayi Nuclear hormone receptor E75 0.003 0.0036 0.0069
Echinococcus granulosus Smad4 0.0043 0.0074 0.0114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.005 0.0095
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0079 0.0121
Trichomonas vaginalis guanylate cyclase, putative 0.0054 0.0105 0.0204
Loa Loa (eye worm) Smad1 0.0043 0.0074 0.0146
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0133 0.0207
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.005 0.0364
Loa Loa (eye worm) hypothetical protein 0.0207 0.0554 0.1088
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0036 0.0035
Schistosoma mansoni z-protein (S1r protein) 0.0045 0.0079 0.0121
Loa Loa (eye worm) hypothetical protein 0.0251 0.0683 0.1341
Echinococcus granulosus agrin 0.0061 0.0127 0.0198
Leishmania major cytochrome p450-like protein 0.0069 0.0149 0.0282
Echinococcus multilocularis tubulin delta chain 0.0436 0.1225 0.1223
Loa Loa (eye worm) PXA domain-containing protein 0.0045 0.0079 0.0154
Brugia malayi Raf kinase 0.0046 0.0082 0.0158
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Schistosoma mansoni lipoxygenase 0.0362 0.1007 0.1579
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0079 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.009 0.021 0.0411
Loa Loa (eye worm) hypothetical protein 0.0045 0.0079 0.0154
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0069 0.0067
Trypanosoma brucei alpha tubulin 0.133 0.3841 0.7545
Leishmania major beta tubulin 0.1756 0.509 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.01 0.0193
Loa Loa (eye worm) hypothetical protein 0.0084 0.0193 0.0379
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0032 0.0043 0.0081
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0232 0.0363
Echinococcus multilocularis Niemann Pick C1 protein 0.0296 0.0813 0.0812
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0069 0.0151 0.0235
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0124
Loa Loa (eye worm) hypothetical protein 0.0061 0.0127 0.025
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0014 0.0027
Echinococcus granulosus lamin 0.0085 0.0197 0.0308
Onchocerca volvulus 0.0533 0.1509 0.6972
Brugia malayi Tubulin beta chain 0.0533 0.1509 0.2963
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0036 0.0071
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0015 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0014
Giardia lamblia Delta tubulin 0.0436 0.1225 0.2398
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0036 0.0069
Schistosoma mansoni smad1 5 8 and 0.0043 0.0074 0.0114
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0024 0.0036
Loa Loa (eye worm) hypothetical protein 0.0045 0.0079 0.0154
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0015 0.0026
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0029 0.0032 0.006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.005 0.0095
Schistosoma mansoni multidrug resistance protein 0.0023 0.0015 0.0021
Echinococcus multilocularis peroxisome assembly protein 26 0.133 0.3841 0.384
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0079 0.0121
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0267 0.0523
Loa Loa (eye worm) jmjC domain-containing protein 0.0068 0.0146 0.0287
Brugia malayi FAD binding domain containing protein 0.002 0.0007 0.001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.009 0.021 0.0414
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0133 0.0207
Schistosoma mansoni thyroid hormone receptor 0.0069 0.0151 0.0235
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0035 0.005 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0014 0.007
Trichomonas vaginalis tubulin beta chain, putative 0.133 0.3841 0.7545
Loa Loa (eye worm) hypothetical protein 0.0045 0.0079 0.0154
Echinococcus granulosus lipoxygenase domain containing protein 0.0165 0.0431 0.0675
Trichomonas vaginalis tubulin epsilon chain, putative 0.1756 0.509 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0014
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0023 0.0015 0.0026
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0032 0.0043 0.0081
Loa Loa (eye worm) sodium-independent organic anion transporter 0.009 0.021 0.0414
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0048 0.0088 0.0137
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0894 0.2565 0.5037
Trypanosoma brucei tubulin gamma chain 0.0998 0.2871 0.5638
Loa Loa (eye worm) hypothetical protein 0.0046 0.0083 0.0164
Echinococcus multilocularis beta tubulin 0.1756 0.509 0.509
Echinococcus granulosus Tubulin beta 2C chain 0.1756 0.509 0.7991
Echinococcus granulosus neuropeptide receptor A26 0.0975 0.2804 0.4401
Schistosoma mansoni tubulin subunit beta 0.1756 0.509 0.7991
Leishmania major beta tubulin 0.1756 0.509 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus granulosus ecdysone induced protein 78C 0.0069 0.0151 0.0235
Trichomonas vaginalis tubulin, putative 0.0465 0.131 0.2571
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0228 0.0617 0.5016
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0054 0.0105 0.0204
Loa Loa (eye worm) hypothetical protein 0.0069 0.0151 0.0297
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0087 0.0204 0.0398
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0036 0.0069
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0023 0.0015 0.0018
Loa Loa (eye worm) tubulin beta-2A chain 0.1756 0.509 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0006 0.0008
Onchocerca volvulus Putative organic anion transporter 0.009 0.021 0.0954
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0116 0.0225
Entamoeba histolytica P-glycoprotein-2, putative 0.0023 0.0015 0.0026
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0149 0.029
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0153 0.0301
Echinococcus granulosus jun protein 0.0266 0.0727 0.1139
Echinococcus granulosus lipoxygenase domain containing protein 0.0165 0.0431 0.0675
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0079 0.0152
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0284 0.0558
Schistosoma mansoni nuclear hormone receptor 0.0069 0.0151 0.0235
Brugia malayi MH2 domain containing protein 0.0631 0.1795 0.3525
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0032 0.0043 0.0081
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0097 0.0232 0.0363
Brugia malayi Tubulin gamma chain 0.0998 0.2871 0.5638
Schistosoma mansoni RAR-like nuclear receptor 0.0069 0.0151 0.0235
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0015 0.0013
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0023 0.0015 0.0077
Brugia malayi CHE-14 protein 0.0089 0.0208 0.0406
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0032 0.0043 0.0041
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0039 0.0275
Toxoplasma gondii target of rapamycin (TOR), putative 0.0071 0.0157 0.0306
Echinococcus granulosus tubulin subunit TubB 0.133 0.3841 0.6029
Echinococcus granulosus tubulin alpha chain 0.133 0.3841 0.6029
Brugia malayi cytochrome P450 0.0022 0.0014 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0284 0.0556
Echinococcus granulosus thioredoxin glutathione reductase 0.01 0.0241 0.0377
Echinococcus granulosus cpg binding protein 0.0096 0.0228 0.0356
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.002 0.0037
Schistosoma mansoni tubulin subunit epsilon 0.0998 0.2869 0.4504
Loa Loa (eye worm) alpha-tubulin 0.133 0.3841 0.7546
Brugia malayi ecdysteroid receptor 0.0069 0.0151 0.0294
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0014 0.007
Schistosoma mansoni hypothetical protein 0.0048 0.0088 0.0137
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0074
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0045 0.0327
Entamoeba histolytica P-glyco protein 6, putative 0.0023 0.0015 0.0026
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0284 0.0556
Trypanosoma cruzi tubulin delta chain 0.0616 0.1751 0.3439
Loa Loa (eye worm) thioredoxin reductase 0.01 0.0241 0.0474
Leishmania major beta tubulin 0.1756 0.509 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0036 0.0147
Echinococcus multilocularis tubulin alpha 3 chain 0.133 0.3841 0.384
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0069 0.0151 0.0235
Echinococcus granulosus ATP dependent DNA helicase Q5 0.003 0.0037 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0014 0.007
Trichomonas vaginalis tubulin alpha chain, putative 0.0533 0.1509 0.2963
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0254 0.0692 0.5613
Echinococcus granulosus geminin 0.0895 0.257 0.4033
Echinococcus granulosus Tubulin alpha 1 chain 0.133 0.3841 0.6029
Giardia lamblia NADH oxidase lateral transfer candidate 0.0035 0.005 0.0087
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0005 0.0006
Trichomonas vaginalis abcb9, putative 0.0023 0.0015 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0079 0.0152
Echinococcus granulosus Niemann Pick C1 protein 0.0296 0.0813 0.1275
Leishmania major beta tubulin 0.1756 0.509 1
Brugia malayi glutathione reductase 0.01 0.0241 0.0472
Echinococcus granulosus beta-adrenergic receptor kinase 0.0045 0.0081 0.0126
Schistosoma mansoni tubulin subunit beta 0.1756 0.509 0.7991
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0114 0.0222
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0043 0.0074 0.0073
Entamoeba histolytica P-glycoprotein-1 0.0023 0.0015 0.0026
Echinococcus multilocularis Smad4 0.0043 0.0074 0.0073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0069 0.0151 0.0235
Onchocerca volvulus Putative organic anion transporter 0.009 0.021 0.0954
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0069 0.0151 0.015
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0042 0.0081
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0797 0.228 0.4478
Echinococcus granulosus tubulin beta 4A class IVa 0.1756 0.509 0.7991
Brugia malayi Tubulin alpha-2 chain 0.133 0.3841 0.7545
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0205 0.0548 0.0858
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.002 0.0029
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0036 0.0035
Plasmodium falciparum tubulin gamma chain 0.0998 0.2871 0.5635
Echinococcus granulosus dnaJ subfamily B 0.0859 0.2463 0.3866
Echinococcus multilocularis tubulin gamma 1 chain 0.0998 0.2871 0.287
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0045 0.0044
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0069 0.0151 0.0235
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0108 0.0209
Mycobacterium ulcerans cell division protein FtsZ 0.0436 0.1225 1
Loa Loa (eye worm) hypothetical protein 0.009 0.021 0.0414
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0096 0.0229 0.0357
Brugia malayi Pre-SET motif family protein 0.0665 0.1894 0.372
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0015 0.0026
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0096 0.0229 0.0447
Schistosoma mansoni lamin 0.0085 0.0197 0.0308
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0015 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Schistosoma mansoni smad1 5 8 and 0.0043 0.0074 0.0114
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.005 0.0095
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0085 0.0197 0.0388
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0284 0.2286
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0069 0.0151 0.0235
Brugia malayi steroid hormone receptor 0.0069 0.0151 0.0294
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0069 0.0151 0.0294
Echinococcus granulosus neuropeptide s receptor 0.0975 0.2804 0.4401
Plasmodium vivax tubulin gamma chain, putative 0.0998 0.2871 0.5635
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0153 0.0239
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.015 0.0387 0.3107
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0015 0.0021
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0096 0.0229 0.0447
Echinococcus multilocularis mitogen activated protein kinase 0.0109 0.0267 0.0266
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0133 0.1046
Brugia malayi bHLH-PAS transcription factor 0.0152 0.0395 0.0773
Echinococcus granulosus Tubulin alpha 1 chain 0.133 0.3841 0.6029
Trichomonas vaginalis conserved hypothetical protein 0.0436 0.1225 0.2404
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0137 0.0266
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0659 0.1877 0.2945
Trypanosoma brucei alpha tubulin, putative 0.0533 0.1509 0.2963
Giardia lamblia Beta tubulin 0.1756 0.509 1
Onchocerca volvulus 0.0061 0.0127 0.0569
Mycobacterium tuberculosis Probable dehydrogenase 0.0228 0.0617 0.5016
Schistosoma mansoni intermediate filament proteins 0.0085 0.0197 0.0308
Plasmodium falciparum tubulin epsilon chain, putative 0.0998 0.2869 0.5632
Echinococcus multilocularis regulator of G protein signaling 0.0045 0.0079 0.0077
Trypanosoma cruzi MFS transporter, putative 0.009 0.021 0.0411
Loa Loa (eye worm) hypothetical protein 0.0061 0.0127 0.025
Entamoeba histolytica tubulin alpha-1 chain 0.133 0.3841 0.7545
Brugia malayi nuclear receptor NHR-88 0.0069 0.0151 0.0294
Schistosoma mansoni cytochrome P450 0.0022 0.0014 0.002
Giardia lamblia Nitric oxide synthase, inducible 0.0029 0.0032 0.0052
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Schistosoma mansoni hypothetical protein 0.0895 0.257 0.4033
Loa Loa (eye worm) MH2 domain-containing protein 0.0043 0.0074 0.0146
Onchocerca volvulus Bile acid receptor homolog 0.0069 0.0151 0.0679
Loa Loa (eye worm) hypothetical protein 0.0041 0.0069 0.0135
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0014 0.007
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0042 0.0083
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0015 0.0013
Plasmodium falciparum alpha tubulin 1 0.133 0.3841 0.7543
Trypanosoma cruzi trypanothione reductase, putative 0.0035 0.005 0.0095
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0006 0.0008
Toxoplasma gondii beta-1 tubulin, putative 0.1756 0.509 1
Brugia malayi hypothetical protein 0.0039 0.0063 0.0121
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0069 0.0151 0.0679
Plasmodium vivax tubulin beta chain, putative 0.1756 0.509 1
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0015 0.0013
Brugia malayi TAZ zinc finger family protein 0.0205 0.0548 0.1074
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0035 0.005 0.2472
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0022 0.004
Leishmania major beta tubulin 0.1756 0.509 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0069 0.0151 0.0235
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.005 0.0087
Echinococcus multilocularis RUN 0.0165 0.0431 0.043
Echinococcus multilocularis thyroid hormone receptor alpha 0.0069 0.0151 0.015
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0079 0.0077
Brugia malayi hypothetical protein 0.0045 0.0079 0.0152
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0015 0.0026
Leishmania major p-glycoprotein 0.0023 0.0015 0.0018
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0436 0.1225 0.2404
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus multilocularis neuropeptide s receptor 0.0975 0.2804 0.2803
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0069 0.0151 0.0294
Entamoeba histolytica hypothetical protein 0.0045 0.0079 0.0152
Trypanosoma brucei trypanothione reductase 0.01 0.0241 0.0472
Plasmodium falciparum tubulin beta chain 0.1756 0.509 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0109 0.0267 0.0523
Loa Loa (eye worm) DR-78 0.003 0.0036 0.0071
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0097 0.0232 0.0231
Loa Loa (eye worm) hypoxia-induced factor 1 0.0638 0.1815 0.3565
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0074
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0006 0.0008
Schistosoma mansoni smad 0.0043 0.0074 0.0114
Loa Loa (eye worm) tubulin alpha 2 0.0894 0.2565 0.5039
Echinococcus multilocularis tubulin epsilon chain 0.0998 0.2869 0.2868
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0039 0.0074
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.002 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Toxoplasma gondii endonuclease IV APN 0.008 0.0182 0.0354
Echinococcus granulosus expressed conserved protein 0.0194 0.0517 0.081
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0153 0.0299
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0063 0.0121
Onchocerca volvulus 0.009 0.021 0.0954
Leishmania major beta tubulin 0.1756 0.509 1
Loa Loa (eye worm) hypothetical protein 0.009 0.021 0.0414
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0055 0.0108 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0105 0.0204
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0284 0.2286
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0254 0.0692 0.5628
Onchocerca volvulus 0.0756 0.2163 1
Brugia malayi MH2 domain containing protein 0.0043 0.0074 0.0143
Loa Loa (eye worm) hypothetical protein 0.0069 0.0151 0.0297
Brugia malayi Smad1 0.0043 0.0074 0.0143
Echinococcus multilocularis dnaJ subfamily B 0.0859 0.2463 0.2462
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0035 0.005 0.0048
Schistosoma mansoni tubulin subunit alpha 0.133 0.3841 0.6029
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0015 0.0026
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0079 0.0077
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0035 0.005 0.0364
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0014 0.007
Schistosoma mansoni steroid hormone receptor ad4bp 0.0069 0.0151 0.0235
Leishmania major trypanothione reductase 0.01 0.0241 0.0464
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0035 0.005 0.0087
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0045 0.0087
Trypanosoma cruzi cytochrome P450, putative 0.0069 0.0149 0.029
Brugia malayi regulator of G-protein signaling rgs-7 0.0045 0.0079 0.0152
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0039 0.1854
Loa Loa (eye worm) hypothetical protein 0.009 0.021 0.0414
Trichomonas vaginalis tubulin alpha chain, putative 0.1756 0.509 1
Schistosoma mansoni loxhd1 0.0165 0.0431 0.0675
Loa Loa (eye worm) hypothetical protein 0.0045 0.0079 0.0154
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0124
Brugia malayi hypothetical protein 0.0388 0.1084 0.2128
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0024 0.0036
Leishmania major protein kinase, putative 0.0055 0.0108 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0172 0.0334
Plasmodium vivax delta tubulin, putative 0.0436 0.1225 0.2398
Schistosoma mansoni hypothetical protein 0.0086 0.0199 0.031
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0015 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0069 0.0151 0.0297
Brugia malayi hypothetical protein 0.0045 0.0079 0.0152
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0267 0.0523
Onchocerca volvulus 0.0069 0.0151 0.0679
Echinococcus multilocularis Tubulin beta 2C chain 0.1756 0.509 0.509
Loa Loa (eye worm) agrin synaptic family protein 0.0061 0.0127 0.025
Schistosoma mansoni niemann-pick C1 (NPC1) 0.021 0.0563 0.0882
Schistosoma mansoni tubulin subunit gamma 0.0998 0.2871 0.4506
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0075 0.0073
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0014 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0105 0.0204
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0133 0.0251
Loa Loa (eye worm) steroid hormone receptor 0.0069 0.0151 0.0297
Leishmania major beta tubulin 0.1756 0.509 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.005 0.0087
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0146 0.0227
Loa Loa (eye worm) doublecortin family protein 0.0165 0.0431 0.0847
Schistosoma mansoni hypothetical protein 0.0086 0.0199 0.031
Echinococcus granulosus tubulin alpha 3 chain 0.133 0.3841 0.6029
Leishmania major gamma-tubulin 0.0998 0.2871 0.5635
Schistosoma mansoni hypothetical protein 0.0165 0.0431 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.01 0.0193
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0096 0.0229 0.0447
Trichomonas vaginalis tubulin beta chain, putative 0.133 0.3841 0.7545
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0087 0.0204 0.0318
Echinococcus multilocularis beta tubulin 0.1756 0.509 0.509
Onchocerca volvulus 0.0208 0.0558 0.2566
Loa Loa (eye worm) phosphatidylinositol 3 0.0096 0.0229 0.045
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0035 0.005 0.0087
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0014 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0081 0.0126
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0284 0.226
Trichomonas vaginalis tubulin beta chain, putative 0.0533 0.1509 0.2963
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0007 0.0012
Leishmania major beta tubulin 0.1756 0.509 1
Schistosoma mansoni hypothetical protein 0.0022 0.0014 0.002
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0023 0.0015 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0014
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0177 0.0276
Loa Loa (eye worm) tubulin alpha-2 chain 0.133 0.3841 0.7546
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0063 0.0121
Brugia malayi hypothetical protein 0.0165 0.0431 0.0845
Schistosoma mansoni DNA helicase recq5 0.003 0.0037 0.0055
Echinococcus granulosus tubulin alpha chain 0.133 0.3841 0.6029
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0036 0.0071
Echinococcus multilocularis Solute carrier organic anion transporter family 0.009 0.021 0.0209
Onchocerca volvulus 0.003 0.0036 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0014
Brugia malayi PAS domain containing protein 0.0206 0.0551 0.1081
Echinococcus granulosus Polycystic kidney disease protein 0.0165 0.0431 0.0675
Brugia malayi isocitrate dehydrogenase 0.0033 0.0045 0.0087
Echinococcus multilocularis lipoxygenase domain containing protein 0.0165 0.0431 0.043
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0015 0.0026
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.004 0.0039
Echinococcus granulosus CREB binding protein 0.0126 0.0318 0.0497
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0012 0.0011
Loa Loa (eye worm) CBP-B 0.0142 0.0365 0.0716
Brugia malayi 6-phosphofructokinase 0.0115 0.0285 0.0557
Brugia malayi tubulin alpha chain - mouse 0.133 0.3841 0.7545
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0015 0.0026
Brugia malayi bZIP transcription factor family protein 0.0266 0.0727 0.1426
Entamoeba histolytica hypothetical protein 0.019 0.0505 0.0989
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0036 0.0055
Echinococcus multilocularis follistatin 0.0061 0.0127 0.0126
Brugia malayi hypothetical protein 0.003 0.0036 0.0069
Trypanosoma brucei zeta tubulin, putative 0.0737 0.2105 0.4134
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0109 0.0267 0.0523
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0005 0.0009
Brugia malayi MH1 domain containing protein 0.0024 0.0018 0.0032
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0045 0.0079 0.0154
Schistosoma mansoni patched 1 0.0089 0.0208 0.0325
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0061 0.0127 0.0247
Echinococcus multilocularis tubulin beta 1 chain 0.1756 0.509 0.509
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0436 0.1225 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0045 0.0079
Plasmodium vivax thioredoxin reductase, putative 0.01 0.0241 0.0464
Schistosoma mansoni hypothetical protein 0.0274 0.0752 0.1178
Echinococcus multilocularis Tubulin alpha 1 chain 0.133 0.3841 0.384
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0267 0.0418
Echinococcus multilocularis tubulin subunit beta 0.1756 0.509 0.509
Schistosoma mansoni tubulin subunit alpha 0.133 0.3841 0.6029
Entamoeba histolytica hypothetical protein 0.019 0.0505 0.0989
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.003 0.0037 0.0035
Echinococcus granulosus Protein patched homolog 1 0.0089 0.0208 0.0325
Brugia malayi Niemann-Pick C1 protein precursor 0.0207 0.0554 0.1085
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0079 0.0121
Trichomonas vaginalis abcb9, putative 0.0023 0.0015 0.0026
Echinococcus multilocularis CREB binding protein 0.0034 0.0047 0.0045
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0014 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0042 0.0081
Onchocerca volvulus Huntingtin homolog 0.0388 0.1084 0.5003
Echinococcus granulosus ATP dependent DNA helicase Q1 0.003 0.0037 0.0055
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0014 0.007
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.0001 0.000000022369
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0079 0.0152
Schistosoma mansoni tubulin subunit beta 0.1756 0.509 0.7991
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0172 0.0334
Brugia malayi hypothetical protein 0.003 0.0036 0.0069
Loa Loa (eye worm) MH2 domain-containing protein 0.0631 0.1795 0.3527
Schistosoma mansoni ap endonuclease 0.002 0.0006 0.0006
Schistosoma mansoni Smad4 0.0019 0.0005 0.0005
Brugia malayi Cell division protein ftsZ 0.0436 0.1225 0.2404
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0076 0.0172 0.0327
Schistosoma mansoni coup transcription factor 0.0069 0.0151 0.0235
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0079 0.0121
Toxoplasma gondii LsmAD domain-containing protein 0.0107 0.0261 0.051
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0037 0.0069
Plasmodium vivax tubulin epsilon chain, putative 0.0998 0.2869 0.5632
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0035 0.005 0.0364
Toxoplasma gondii histone lysine methyltransferase SET1 0.0178 0.0471 0.0922
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0267 0.0523
Loa Loa (eye worm) hypothetical protein 0.0388 0.1084 0.213
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.002 0.012
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0045 0.0089
Brugia malayi hypothetical protein 0.009 0.021 0.0411
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0069 0.0151 0.0297
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0284 0.0548
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0131 0.0203
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0079 0.0121
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0079 0.0077
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0062
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0054 0.0105 0.0163
Loa Loa (eye worm) hypothetical protein 0.0388 0.1084 0.213
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0014 0.007
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0035 0.005 0.0087
Schistosoma mansoni CREB-binding protein 2 0.0205 0.0548 0.0858
Trypanosoma brucei beta tubulin 0.0969 0.2785 0.5471
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.002 0.0774
Loa Loa (eye worm) hypothetical protein 0.0691 0.1971 0.3873
Trichomonas vaginalis helicase, putative 0.002 0.0008 0.0014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0146 0.0227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Brugia malayi MH1 domain containing protein 0.0043 0.0074 0.0143
Brugia malayi Intermediate filament tail domain containing protein 0.0085 0.0197 0.0385
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.001 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0157 0.0306
Echinococcus multilocularis hypothetical protein 0.133 0.3841 0.384
Schistosoma mansoni alpha tubulin 0.133 0.3841 0.6029
Treponema pallidum NADH oxidase 0.0035 0.005 0.0364
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0045 0.0044
Echinococcus granulosus tubulin alpha 3 chain 0.133 0.3841 0.6029
Echinococcus granulosus organic anion transporting polypeptide 30B 0.009 0.021 0.0328
Echinococcus multilocularis transfer RNA-Lys 0.0152 0.0395 0.0393
Loa Loa (eye worm) RecQ helicase 0.0043 0.0075 0.0147
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Trichomonas vaginalis mercuric reductase, putative 0.0035 0.005 0.0095
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0015 0.0026
Echinococcus multilocularis mitogen activated protein kinase 3 0.0109 0.0267 0.0266
Toxoplasma gondii exonuclease III APE 0.002 0.0006 0.0008
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0036 0.0147
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0054 0.0105 0.0104
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0045 0.0081 0.016
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0069 0.0151 0.015
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0109 0.0267 0.0525
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0042 0.0073
Echinococcus multilocularis raf serine:threonine protein kinase 0.0046 0.0082 0.008
Loa Loa (eye worm) hypothetical protein 0.009 0.021 0.0414
Onchocerca volvulus 0.0085 0.0197 0.0894
Echinococcus multilocularis thioredoxin glutathione reductase 0.01 0.0241 0.024
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0042 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0069 0.0151 0.0294
Giardia lamblia Sgs1 DNA helicase, putative 0.003 0.0037 0.0061
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0045 0.0044
Schistosoma mansoni rab6-interacting 0.0165 0.0431 0.0675
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0063 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0105 0.0204
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0015 0.0026
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0015 0.0026
Echinococcus multilocularis Niemann Pick C1 protein 0.0207 0.0554 0.0552
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0069 0.0151 0.0294
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0133 0.1046
Entamoeba histolytica hypothetical protein 0.0025 0.002 0.0037
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0036 0.0069
Echinococcus granulosus CREB binding protein 0.0205 0.0548 0.0858
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0015 0.0026
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0014 0.0036
Leishmania major beta tubulin 0.1756 0.509 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0042 0.0081
Echinococcus multilocularis Tubulin alpha 1 chain 0.133 0.3841 0.384
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Echinococcus granulosus expressed protein 0.0773 0.2212 0.3471
Trichomonas vaginalis DNA helicase recq, putative 0.0033 0.0045 0.0085
Toxoplasma gondii alpha-tubulin I, putative 0.133 0.3841 0.7545
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0228 0.0617 0.4999
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0063 0.0121
Trichomonas vaginalis taga, putative 0.0023 0.0015 0.0026
Brugia malayi MH1 domain containing protein 0.0043 0.0074 0.0143
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0124
Onchocerca volvulus 0.0209 0.056 0.2572
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Trypanosoma brucei protein kinase, putative 0.0109 0.0267 0.0523
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0069 0.0151 0.0294
Toxoplasma gondii beta-tubulin, putative 0.1756 0.509 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0036 0.0071
Onchocerca volvulus 0.0165 0.0431 0.1978
Echinococcus multilocularis tubulin alpha chain 0.133 0.3841 0.384
Brugia malayi hypothetical protein 0.019 0.0505 0.0989
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0284 0.0444
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0035 0.005 0.0095
Brugia malayi multidrug resistance protein 3 0.0023 0.0015 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.0054 0.0105 0.0204
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0061 0.0127 0.0247
Echinococcus multilocularis tumor protein p63 0.1424 0.4116 0.4115
Trypanosoma brucei beta tubulin 0.1756 0.509 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0151 0.0297
Trypanosoma brucei beta tubulin 0.1756 0.509 1
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0284 0.0556
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0079 0.0077
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0042 0.0073
Brugia malayi nuclear hormone receptor 0.003 0.0036 0.0069
Loa Loa (eye worm) hypothetical protein 0.0069 0.0151 0.0297
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0109 0.0267 0.0515
Echinococcus multilocularis CREB binding protein 0.0034 0.0047 0.0045
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Trypanosoma brucei epsilon tubulin 0.0998 0.2869 0.5636
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0081 0.0126
Trypanosoma brucei beta tubulin 0.1756 0.509 1
Brugia malayi PXA domain containing protein 0.0045 0.0079 0.0152
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0045 0.0087
Schistosoma mansoni microtubule-associated protein tau 0.2193 0.637 1
Trypanosoma cruzi epsilon tubulin, putative 0.0998 0.2869 0.5636
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0036 0.0035
Echinococcus multilocularis Tubulin beta 2C chain 0.1756 0.509 0.509
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.01 0.0194
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0063 0.0062
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Mycobacterium leprae Possible regulatory protein 0.0054 0.0105 0.0785
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0014 0.007
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0019
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0284 0.0556
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0006 0.0008
Brugia malayi alpha-tubulin 0.133 0.3841 0.7545
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.008 0.0182 0.0357
Trypanosoma cruzi PAB1-binding protein , putative 0.0107 0.0261 0.051
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0039 0.0063 0.0097
Entamoeba histolytica tubulin family protein 0.1756 0.509 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0061 0.0127 0.0247
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0036 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0063 0.0121
Echinococcus multilocularis tubulin alpha 3 chain 0.133 0.3841 0.384
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.005 0.0095
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Echinococcus multilocularis CREB binding protein 0.014 0.0359 0.0358
Brugia malayi Tubulin alpha chain 0.0436 0.1225 0.2404
Echinococcus granulosus tubulin alpha 1C chain 0.133 0.3841 0.6029
Echinococcus granulosus tubulin subunit beta 0.1756 0.509 0.7991
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.005 0.0364
Echinococcus multilocularis methionine synthase reductase 0.002 0.0007 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.001 0.0034
Echinococcus granulosus tumor protein p63 0.1424 0.4116 0.6461
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.0683 0.107
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0075 0.0144
Brugia malayi 6-phosphofructokinase 0.0115 0.0284 0.0556
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.015 0.0387 0.313
Loa Loa (eye worm) pax transcription factor protein 2 0.0255 0.0696 0.1367
Schistosoma mansoni multidrug resistance protein 0.0023 0.0015 0.0021
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0035 0.005 0.0095
Brugia malayi CXXC zinc finger family protein 0.009 0.0213 0.0416
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0015 0.0026
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Mycobacterium tuberculosis Probable oxidoreductase 0.0254 0.0692 0.5628
Trichomonas vaginalis tubulin beta chain, putative 0.1756 0.509 1
Echinococcus multilocularis smad 0.0043 0.0074 0.0073
Leishmania major delta tubulin, putative 0.0616 0.1751 0.3433
Trichomonas vaginalis abcb9, putative 0.0023 0.0015 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0069 0.0151 0.0297
Plasmodium falciparum tubulin delta chain, putative 0.0436 0.1225 0.2398
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0195 0.052 0.0815
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0069 0.0151 0.0294
Echinococcus multilocularis 0.0022 0.0014 0.0013
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0284 0.0283
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0045 0.0087
Schistosoma mansoni alpha tubulin 0.133 0.3841 0.6029
Loa Loa (eye worm) hypothetical protein 0.0054 0.0105 0.0206
Leishmania major beta tubulin 0.1756 0.509 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0069 0.0151 0.015
Trypanosoma cruzi zeta tubulin, putative 0.0737 0.2105 0.4134
Leishmania major beta tubulin 0.1756 0.509 1
Brugia malayi phosphofructokinase 0.0115 0.0284 0.0556
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0014 0.007
Giardia lamblia Gamma tubulin 0.0998 0.2871 0.5635
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0074
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0039 0.0063 0.0124
Trichomonas vaginalis tubulin beta chain, putative 0.133 0.3841 0.7545
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0061 0.0127 0.0247
Onchocerca volvulus 0.009 0.021 0.0954
Loa Loa (eye worm) hypothetical protein 0.0069 0.0151 0.0297
Plasmodium falciparum thioredoxin reductase 0.01 0.0241 0.0464
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0208 0.0406
Loa Loa (eye worm) FAD binding domain-containing protein 0.002 0.0007 0.0013
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0039 0.0063 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0014
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0133 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0069 0.0151 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0157 0.0306
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0014 0.007
Trichomonas vaginalis tubulin epsilon chain, putative 0.133 0.3841 0.7545
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0014 0.007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0133 0.1046
Schistosoma mansoni retinoic acid receptor RXR 0.0069 0.0151 0.0235
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0045 0.0087
Schistosoma mansoni smad 0.0019 0.0005 0.0005
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.002 0.0037
Loa Loa (eye worm) hypothetical protein 0.004 0.0064 0.0126
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0015 0.0026
Loa Loa (eye worm) ATP-dependent DNA helicase 0.003 0.0037 0.0072
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0039 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0012
Schistosoma mansoni cpg binding protein 0.0096 0.0228 0.0356
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0149 0.0293
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0024 0.0023
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0182 0.0346
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0023 0.0042
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.002 0.012
Schistosoma mansoni jun-related protein 0.0216 0.0581 0.091
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0015 0.0013
Echinococcus multilocularis tubulin alpha chain 0.133 0.3841 0.384
Brugia malayi Pre-SET motif family protein 0.0097 0.0232 0.0454
Toxoplasma gondii tubulin, putative 0.0029 0.0032 0.0061
Onchocerca volvulus 0.0152 0.0395 0.1807
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0069 0.0151 0.0235
Loa Loa (eye worm) hypothetical protein 0.133 0.3841 0.7546
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0131 0.0203
Entamoeba histolytica hypothetical protein 0.019 0.0505 0.0989
Loa Loa (eye worm) tubulin alpha 2 0.0361 0.1004 0.1972
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.008 0.0182 0.1444
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0014 0.007
Brugia malayi Nuclear hormone receptor E75 0.003 0.0036 0.0069
Plasmodium falciparum LCCL domain-containing protein 0.0165 0.0431 0.0837
Echinococcus multilocularis musashi 0.0085 0.0197 0.0196
Brugia malayi tubulin alpha-2 chain 0.133 0.3841 0.7545
Echinococcus granulosus follistatin 0.0061 0.0127 0.0198
Plasmodium falciparum nitric oxide synthase, putative 0.0032 0.0043 0.0073
Brugia malayi Tubulin beta-1 chain 0.1756 0.509 1
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.002 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0082 0.0126
Brugia malayi conserved hypotetical protein 0.003 0.0036 0.0069
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0035 0.005 0.0087
Schistosoma mansoni cytochrome P450 reductase 0.0032 0.0043 0.0065
Brugia malayi intermediate filament protein 0.0085 0.0197 0.0385
Loa Loa (eye worm) glutathione reductase 0.01 0.0241 0.0474
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0131 0.013
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0005 0.0005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0228 0.0617 0.5016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0131 0.0254
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0023 0.0015 0.047
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0079 0.0121
Echinococcus granulosus lamin dm0 0.0085 0.0197 0.0308
Echinococcus multilocularis Tubulin beta 2C chain 0.1756 0.509 0.509
Mycobacterium ulcerans endonuclease IV 0.008 0.0182 0.1444
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0042 0.0081
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0153 0.0299
Trichomonas vaginalis tubulin alpha chain, putative 0.0533 0.1509 0.2963
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0015 0.0021
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0014 0.007
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0045 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0082 0.0188 0.0367
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0036 0.0055
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0079 0.0121
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0098 0.019
Loa Loa (eye worm) hypothetical protein 0.0069 0.0151 0.0297
Mycobacterium ulcerans hypothetical protein 0.0021 0.001 0.0034
Schistosoma mansoni survival motor neuron protein 0.0051 0.0098 0.0152
Loa Loa (eye worm) hypothetical protein 0.0089 0.0208 0.0409
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0014 0.007
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0036 0.0055
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.004 0.0061
Loa Loa (eye worm) hypothetical protein 0.0032 0.0043 0.0084
Loa Loa (eye worm) intermediate filament protein 0.0085 0.0197 0.0388
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0079 0.0121
Brugia malayi MAP kinase sur-1 0.0109 0.0267 0.0523
Schistosoma mansoni agrin 0.0061 0.0127 0.0198
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0006 0.0011
Echinococcus granulosus Tubulin beta 2C chain 0.1756 0.509 0.7991
Brugia malayi Pax transcription factor protein 2 0.0255 0.0696 0.1365
Trichomonas vaginalis tubulin beta chain, putative 0.133 0.3841 0.7545
Trypanosoma brucei epsilon tubulin 0.0998 0.2869 0.5636
Onchocerca volvulus 0.0097 0.0232 0.1056
Giardia lamblia Beta tubulin 0.1756 0.509 1
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0284 0.0444
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0465 0.1309 0.2569
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0035 0.005 0.0087
Schistosoma mansoni DNA helicase recq1 0.003 0.0037 0.0055
Plasmodium falciparum multidrug resistance protein 1 0.0023 0.0015 0.0018
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0014 0.0013
Echinococcus granulosus tubulin alpha chain 0.133 0.3841 0.6029
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0079 0.0121
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0096 0.0229 0.044
Plasmodium vivax flavodoxin domain containing protein 0.0029 0.0032 0.0052
Schistosoma mansoni nuclear receptor 0.003 0.0036 0.0055
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0096 0.0229 0.0447
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0014
Plasmodium falciparum alpha tubulin 2 0.133 0.3841 0.7543
Echinococcus granulosus RUN 0.0165 0.0431 0.0675
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0133 0.0207
Treponema pallidum cell division protein FtsZ 0.0436 0.1225 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0096 0.0229 0.044
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0039 0.0066
Loa Loa (eye worm) hypothetical protein 0.0069 0.0151 0.0297
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0079 0.0121
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0035 0.005 0.0076
Schistosoma mansoni multidrug resistance protein 0.0023 0.0015 0.0021
Loa Loa (eye worm) tubulin gamma chain 0.0998 0.2871 0.564
Entamoeba histolytica P-glycoprotein 5, putative 0.0023 0.0015 0.0026
Echinococcus multilocularis microtubule associated protein 2 0.2193 0.637 0.6369
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0105 0.0204
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.005 0.0095
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0006 0.0008
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0024 0.0036
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.004 0.0065 0.0125
Onchocerca volvulus 0.003 0.0036 0.0147
Brugia malayi sodium-independent organic anion transporter family protein 0.009 0.021 0.0411
Onchocerca volvulus Protein ultraspiracle homolog 0.0069 0.0151 0.0679
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0015 0.0026
Loa Loa (eye worm) tubulin alpha 2 0.0894 0.2565 0.5039
Trichomonas vaginalis tubulin alpha chain, putative 0.0969 0.2785 0.5471
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0096 0.0229 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0079 0.0152
Loa Loa (eye worm) hypothetical protein 0.0894 0.2565 0.5039
Loa Loa (eye worm) nuclear factor I 0.0024 0.0018 0.0035
Loa Loa (eye worm) beta-tubulin 0.1756 0.509 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0029
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0097 0.0232 0.0454
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0063 0.0062
Schistosoma mansoni ap endonuclease 0.002 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0069 0.0151 0.0294
Schistosoma mansoni follistatin 0.0061 0.0127 0.0198
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0014 0.007
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0015 0.0026
Leishmania major cytochrome p450-like protein 0.0022 0.0014 0.0017
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0014 0.0025
Loa Loa (eye worm) tubulin beta-4 chain 0.1756 0.509 1
Schistosoma mansoni thyroid hormone receptor 0.0069 0.0151 0.0235
Schistosoma mansoni tubulin subunit delta 0.0436 0.1225 0.1921
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0023 0.0015 0.0029
Giardia lamblia Epsilon tubulin 0.0465 0.1309 0.2563
Giardia lamblia Fructose-bisphosphate aldolase 0.0307 0.0847 0.1654
Trichomonas vaginalis glutathione reductase, putative 0.0035 0.005 0.0095
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0665 0.1894 0.3721
Leishmania major epsilon tubulin, putative 0.0998 0.2869 0.5632
Toxoplasma gondii thioredoxin reductase 0.01 0.0241 0.0472
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0284 0.0558
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0014 0.007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0014
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0003
Echinococcus multilocularis CREB binding protein 0.0034 0.0047 0.0045
Echinococcus granulosus CREB binding protein 0.0034 0.0047 0.0071
Brugia malayi A-kinase anchor protein 10, precursor 0.0045 0.0079 0.0152
Brugia malayi Nuclear hormone receptor-like 1 0.0069 0.0151 0.0294
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0069 0.0151 0.0297
Trypanosoma cruzi alpha tubulin, putative 0.133 0.3841 0.7545
Trichomonas vaginalis adenylate cyclase, putative 0.0054 0.0105 0.0204
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.002 0.012
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0036 0.0055
Loa Loa (eye worm) cytochrome P450 0.0022 0.0014 0.0027
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0005 0.0003
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0032 0.0043 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0069 0.0151 0.0297
Echinococcus granulosus intermediate filament protein 0.0085 0.0197 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0436 0.1225 0.2404
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0042 0.0081
Brugia malayi nuclear receptor NHR-67 0.003 0.0036 0.0069
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0014 0.007
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1756 0.509 0.509
Brugia malayi hypothetical protein 0.0107 0.0261 0.051
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0105 0.0204
Echinococcus multilocularis tubulin alpha 1C chain 0.133 0.3841 0.384
Schistosoma mansoni nuclear receptor 0.003 0.0036 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0107 0.0261 0.0502
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0969 0.2785 0.5471
Toxoplasma gondii beta tubulin 0.1756 0.509 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0014
Echinococcus granulosus tubulin gamma 1 chain 0.0998 0.2871 0.4506
Brugia malayi Tubulin beta chain 0.0436 0.1225 0.2404
Schistosoma mansoni organic anion transporter 0.009 0.021 0.0328
Leishmania major cytochrome p450-like protein 0.0022 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0045 0.0079 0.0154
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0063 0.0097
Onchocerca volvulus Huntingtin homolog 0.0388 0.1084 0.5003
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0045 0.0087
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.019 0.0505 0.0504
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0232 0.0363
Toxoplasma gondii alpha tubulin TUBA1 0.133 0.3841 0.7545
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0014 0.007
Echinococcus multilocularis beta adrenergic receptor kinase 0.0045 0.0081 0.008
Trichomonas vaginalis tubulin alpha chain, putative 0.0533 0.1509 0.2963
Onchocerca volvulus 0.0085 0.0197 0.0894
Brugia malayi hypothetical protein 0.0165 0.0431 0.0845
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0011
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0015 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.005 0.0095
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0015 0.0026
Schistosoma mansoni hypothetical protein 0.019 0.0505 0.0791
Schistosoma mansoni Smad4 0.0043 0.0074 0.0114
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0063 0.0097
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0894 0.2565 0.5039
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0008 0.0014
Echinococcus multilocularis tubulin alpha chain 0.133 0.3841 0.384
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0082 0.0158
Schistosoma mansoni tubulin subunit beta 0.0436 0.1225 0.1921
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0069 0.0151 0.0294
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0284 0.0556
Mycobacterium leprae putative cytochrome p450 0.0022 0.0014 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0074
Brugia malayi Doublecortin family protein 0.0165 0.0431 0.0845
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0014 0.007
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0035 0.005 0.0076
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0063 0.0062
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0076 0.0172 0.0335
Trypanosoma brucei alpha tubulin 0.133 0.3841 0.7545
Treponema pallidum fructose-bisphosphate aldolase 0.0307 0.0847 0.69
Loa Loa (eye worm) CYP4Cod1 0.0069 0.0149 0.0293
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0063 0.0121
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0254 0.0692 0.5628
Leishmania major beta tubulin 0.1756 0.509 1
Entamoeba histolytica hypothetical protein 0.0045 0.0079 0.0152
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0061 0.0127 0.025
Entamoeba histolytica hypothetical protein 0.019 0.0505 0.0989
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0228 0.0617 0.5016
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.002 0.0029
Toxoplasma gondii NADPH-glutathione reductase 0.0035 0.005 0.0095
Mycobacterium tuberculosis Probable reductase 0.0228 0.0617 0.5016
Brugia malayi follicle stimulating hormone receptor 0.0257 0.0701 0.1375
Trypanosoma brucei beta tubulin 0.1756 0.509 1
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0032 0.0043 0.0081
Plasmodium falciparum thioredoxin reductase 0.0035 0.005 0.0087
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0207 0.0554 0.1085
Loa Loa (eye worm) hypothetical protein 0.0208 0.0558 0.1097
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0014 0.002
Plasmodium vivax SET domain protein, putative 0.0097 0.0232 0.0446
Giardia lamblia Alpha-tubulin 0.133 0.3841 0.7543
Trichomonas vaginalis tubulin gamma chain, putative 0.1756 0.509 1
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.003 0.0037 0.0061
Chlamydia trachomatis endonuclease IV 0.008 0.0182 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0036 0.0055
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus multilocularis jun protein 0.0266 0.0727 0.0726
Echinococcus granulosus tubulin alpha 0.0969 0.2785 0.4372
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0015 0.0021
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0069 0.0151 0.0235
Brugia malayi Cytochrome P450 family protein 0.0022 0.0014 0.0025
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0092 0.0216 0.0338
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0036 0.0035
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0045 0.0079 0.0077
Leishmania major beta tubulin 0.1756 0.509 1
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0054 0.0105 0.5625
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0124
Giardia lamblia Alpha-tubulin 0.133 0.3841 0.7543
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0014 0.0025
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0045 0.0079
Echinococcus multilocularis lamin 0.0085 0.0197 0.0196
Schistosoma mansoni nuclear hormone receptor 0.003 0.0036 0.0055
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0054 0.0105 0.0204
Trypanosoma brucei zeta tubulin 0.0737 0.2105 0.4134
Trypanosoma brucei alpha tubulin 0.133 0.3841 0.7545
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0079 0.0121
Loa Loa (eye worm) hypothetical protein 0.009 0.021 0.0414
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0032 0.0043 0.0065
Echinococcus granulosus beta tubulin 0.1756 0.509 0.7991
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0055 0.0108 0.0209
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0005 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0069 0.0149 0.0293
Brugia malayi hypothetical protein 0.0039 0.0063 0.0121
Loa Loa (eye worm) transcription factor SMAD2 0.0631 0.1795 0.3527
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0124
Brugia malayi nuclear receptor RXR 0.0039 0.0063 0.0121
Echinococcus granulosus beta tubulin 0.1756 0.509 0.7991
Loa Loa (eye worm) raf kinase 0.0046 0.0082 0.016
Brugia malayi nuclear receptor NHR-88 0.003 0.0036 0.0069
Mycobacterium ulcerans epimerase 0.0021 0.001 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0069 0.0151 0.0297
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0153 0.0299
Entamoeba histolytica recQ family helicase, putative 0.0033 0.0045 0.0085
Echinococcus multilocularis expressed protein 0.0061 0.0127 0.0126
Schistosoma mansoni hypothetical protein 0.0216 0.0581 0.091
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0036 0.0069
Loa Loa (eye worm) MH1 domain-containing protein 0.0043 0.0074 0.0146
Trichomonas vaginalis tubulin epsilon chain, putative 0.133 0.3841 0.7545
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0037 0.0069
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Echinococcus multilocularis protein dispatched 1 0.0101 0.0245 0.0243
Echinococcus multilocularis tubulin alpha chain 0.133 0.3841 0.384
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0096 0.0229 0.0447
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0014 0.0025
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Schistosoma mansoni transcription factor LCR-F1 0.019 0.0505 0.0791
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0045 0.0069
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0032 0.0043 0.0081
Echinococcus granulosus FTZ F1 alpha 0.0069 0.0151 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0116 0.0225
Schistosoma mansoni polycystin 1-related 0.0165 0.0431 0.0675
Echinococcus multilocularis tubulin alpha 0.0969 0.2785 0.2784
Echinococcus multilocularis Tubulin beta 2C chain 0.1756 0.509 0.509
Echinococcus granulosus Tubulin alpha 1 chain 0.133 0.3841 0.6029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0157 0.0306
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0109 0.0267 0.0523
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0069 0.0151 0.0294
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0028
Trypanosoma cruzi zeta tubulin, putative 0.0737 0.2105 0.4134
Brugia malayi Thioredoxin reductase 0.01 0.0241 0.0472
Brugia malayi hypothetical protein 0.0209 0.056 0.1097
Echinococcus granulosus lysine specific demethylase 5A 0.0068 0.0146 0.0227
Brugia malayi PXA domain containing protein 0.0045 0.0079 0.0152
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Onchocerca volvulus 0.0165 0.0431 0.1978
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0157 0.0306
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0014 0.007
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0045 0.0087
Echinococcus granulosus Tubulin beta 2C chain 0.1756 0.509 0.7991
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0063 0.0121
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0133 0.0259
Schistosoma mansoni lamin 0.0085 0.0197 0.0308
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0069 0.0151 0.015
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0063 0.0097
Brugia malayi hypothetical protein 0.0691 0.1971 0.3871
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0063 0.0121
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0267 0.0523
Brugia malayi Steroid receptor seven-up type 2 0.0069 0.0151 0.0294
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0063 0.0097
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0014 0.007
Loa Loa (eye worm) hypothetical protein 0.0045 0.0079 0.0154
Schistosoma mansoni lipoxygenase 0.0659 0.1877 0.2945
Brugia malayi hypoxia-induced factor 1 0.0638 0.1815 0.3563
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0006 0.0008
Loa Loa (eye worm) tubulin beta-1 chain 0.1756 0.509 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0436 0.1225 0.2404
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.005 0.0095
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0024 0.0036
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0079 0.0121
Echinococcus granulosus tubulin alpha 1C chain 0.133 0.3841 0.6029
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0284 0.0556
Echinococcus granulosus tubulin delta chain 0.0436 0.1225 0.1921
Echinococcus granulosus bloom syndrome protein 0.0043 0.0075 0.0115
Loa Loa (eye worm) hypothetical protein 0.0797 0.228 0.448
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0054 0.0105 0.0206
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0096 0.0229 0.0447
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0079 0.0121
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0014 0.007
Schistosoma mansoni cellular tumor antigen P53 0.0208 0.0558 0.0875
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0172 0.0334
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.008 0.0182 0.1415
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0014 0.007
Trichomonas vaginalis set domain proteins, putative 0.0756 0.2162 0.4246
Echinococcus granulosus mothers against decapentaplegic 5 0.0043 0.0074 0.0114
Schistosoma mansoni zinc finger protein 0.003 0.0036 0.0055
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.0081 0.016
Loa Loa (eye worm) tubulin beta chain 0.0436 0.1225 0.2406
Echinococcus multilocularis tubulin subunit TubB 0.133 0.3841 0.384
Entamoeba histolytica tubulin gamma chain 0.0998 0.2871 0.5638
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Echinococcus multilocularis Regulator of G protein signaling 20 0.0045 0.0079 0.0077
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.009 0.021 0.0209
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0063 0.0121
Schistosoma mansoni organic anion transporter 0.009 0.021 0.0328
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0081 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0116 0.0225
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0014 0.007
Plasmodium vivax glutathione reductase, putative 0.01 0.0241 0.0464
Mycobacterium ulcerans putative regulatory protein 0.0152 0.0395 0.3192
Brugia malayi Tubulin alpha chain 0.133 0.3841 0.7545
Trypanosoma brucei alpha tubulin 0.133 0.3841 0.7545
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0069 0.0149 0.1177
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.01 0.0241 0.1935
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0037 0.0069
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.008 0.0182 0.0354
Schistosoma mansoni tubulin subunit beta 0.1756 0.509 0.7991
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0015 0.0026
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0015 0.0021
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0035 0.005 0.0095
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Plasmodium falciparum glutathione reductase 0.0035 0.005 0.0087
Schistosoma mansoni smad1 5 8 and 0.0043 0.0074 0.0114
Leishmania major zeta tubulin, putative 0.0737 0.2105 0.4129
Echinococcus granulosus tubulin epsilon chain 0.0998 0.2869 0.4504
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0032 0.0043 0.0073
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0039 0.0066
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.002 0.0007 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0069 0.0151 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0157 0.0306
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0014 0.007
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0069 0.0151 0.015
Trichomonas vaginalis tubulin beta chain, putative 0.133 0.3841 0.7545
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0074
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.0683 0.0681
Echinococcus granulosus histone lysine methyltransferase setb 0.0097 0.0232 0.0363
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0015 0.0021
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0035 0.005 0.0095
Echinococcus multilocularis cpg binding protein 0.0096 0.0228 0.0227
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.015 0.0387 0.313
Trichomonas vaginalis tubulin gamma chain, putative 0.0998 0.2871 0.5638
Onchocerca volvulus 0.009 0.021 0.0954
Onchocerca volvulus 0.0051 0.0098 0.0434
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0036 0.0055
Loa Loa (eye worm) hypothetical protein 0.009 0.021 0.0414
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0032 0.0043 0.0065
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0153 0.0291
Echinococcus multilocularis FTZ F1 alpha 0.0069 0.0151 0.015
Trypanosoma brucei cytochrome P450, putative 0.0069 0.0149 0.029
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0014 0.007
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0015 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0014 0.007
Echinococcus granulosus tubulin alpha chain 0.133 0.3841 0.6029
Plasmodium vivax multidomain scavenger receptor, putative 0.0165 0.0431 0.0837
Giardia lamblia Hypothetical protein 0.0029 0.0032 0.0052
Echinococcus granulosus Tubulin beta 2C chain 0.1756 0.509 0.7991
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0067 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0069 0.0151 0.0294
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0023 0.0042
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Trypanosoma cruzi epsilon tubulin, putative 0.0998 0.2869 0.5636
Schistosoma mansoni Smad4 0.0019 0.0005 0.0005
Leishmania major alpha tubulin 0.133 0.3841 0.7543
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0063 0.0121
Trichomonas vaginalis tubulin beta chain, putative 0.133 0.3841 0.7545
Echinococcus multilocularis Tubulin alpha 1 chain 0.133 0.3841 0.384
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0032 0.0043 0.0306
Onchocerca volvulus Putative organic anion transporter 0.009 0.021 0.0954
Echinococcus multilocularis Tubulin beta 2C chain 0.1756 0.509 0.509
Echinococcus multilocularis agrin 0.0061 0.0127 0.0126
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0014 0.007
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.0267 0.0523
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0177 0.0176
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0015 0.0026
Echinococcus multilocularis mothers against decapentaplegic 5 0.0043 0.0074 0.0073
Schistosoma mansoni hypothetical protein 0.0086 0.0199 0.031
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0005 0.0005
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0067 0.0103
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0105 0.0204
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0096 0.023 0.0451
Schistosoma mansoni regulator of G protein signaling 0.0046 0.0082 0.0126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.005 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0165 0.0431 0.0847
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0045 0.0087
Brugia malayi nuclear receptor RXR 0.003 0.0036 0.0069
Leishmania major hypothetical protein, conserved 0.0107 0.0261 0.0502
Trypanosoma brucei epsilon tubulin 0.0969 0.2785 0.5471
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0074
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0014 0.007
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.005 0.0095
Loa Loa (eye worm) hypothetical protein 0.0107 0.0261 0.0512
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0045 0.0085
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0071
Brugia malayi hypothetical protein 0.009 0.021 0.0411
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0014
Entamoeba histolytica hypothetical protein 0.0045 0.0079 0.0152
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0182 0.0346
Trypanosoma cruzi tubulin delta chain 0.0616 0.1751 0.3439
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0014
Echinococcus granulosus Solute carrier organic anion transporter family 0.009 0.021 0.0328
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0232 0.0363
Onchocerca volvulus 0.009 0.0213 0.0967
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0015 0.0026
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0015 0.0026
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0097 0.0232 0.0231
Brugia malayi Cytochrome P450 family protein 0.0069 0.0149 0.029
Brugia malayi flavodoxin family protein 0.0032 0.0043 0.0081
Giardia lamblia Kinase, CMGC MAPK 0.0109 0.0267 0.0515
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0039 0.0074
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0006 0.0008
Echinococcus multilocularis sterol regulatory element binding protein 0.0089 0.0208 0.0207
Echinococcus multilocularis expressed protein 0.0773 0.2212 0.221
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0266 0.0727 0.0726
Echinococcus granulosus tubulin beta 1 chain 0.1756 0.509 0.7991
Echinococcus multilocularis ecdysone induced protein 78C 0.0069 0.0151 0.015
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0048 0.0088 0.0087
Echinococcus granulosus tubulin alpha chain 0.133 0.3841 0.6029
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0108 0.0209
Onchocerca volvulus 0.0255 0.0696 0.3203
Schistosoma mansoni tubulin subunit alpha 0.133 0.3841 0.6029
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0105 0.0204
Echinococcus multilocularis protein patched 0.0089 0.0208 0.0207
Leishmania major beta tubulin 0.1756 0.509 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0014 0.007
Echinococcus granulosus smad 0.0043 0.0074 0.0114
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0079 0.0077
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0069 0.0105
Plasmodium vivax multidrug resistance protein 1, putative 0.0023 0.0015 0.0018
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0015 0.0026
Trypanosoma cruzi tubulin gamma chain 0.0998 0.2871 0.5638
Trypanosoma cruzi trypanothione reductase, putative 0.01 0.0241 0.0472
Trichomonas vaginalis tubulin, putative 0.1756 0.509 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.0081 0.0157
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0032 0.0043 0.0081
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0533 0.1509 0.2963
Plasmodium falciparum glutathione reductase 0.01 0.0241 0.0464
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0082 0.0161
Loa Loa (eye worm) BEN-1 protein 0.1756 0.509 1
Schistosoma mansoni hypothetical protein 0.0086 0.0199 0.031
Loa Loa (eye worm) hypothetical protein 0.0165 0.0431 0.0847
Echinococcus granulosus mitogen activated protein kinase 0.0109 0.0267 0.0418
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.002 0.0029
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0045 0.0079 0.0152
Echinococcus granulosus aryl hydrocarbon receptor 0.0054 0.0105 0.0163
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0096 0.0229 0.0447
Loa Loa (eye worm) BEN-1 protein 0.1756 0.509 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0045 0.0044
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0045 0.0079 0.0121
Echinococcus granulosus L aminoadipate semialdehyde 0.0087 0.0204 0.0318
Trichomonas vaginalis tubulin, putative 0.0533 0.1509 0.2963
Mycobacterium leprae conserved hypothetical protein 0.0025 0.002 0.0087
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0045 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0847 0.1661
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0022 0.0014 0.002
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0061 0.0127 0.0247
Brugia malayi sodium-independent organic anion transporter family protein 0.009 0.021 0.0411
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0045 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0157 0.0306
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0114 0.0222
Loa Loa (eye worm) RGS-3 protein 0.0045 0.0079 0.0154
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0006 0.0004
Echinococcus multilocularis L aminoadipate semialdehyde 0.0087 0.0204 0.0202
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0069 0.0151 0.0294
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.019 0.0505 0.0791
Brugia malayi sodium-independent organic anion transporter family protein 0.009 0.021 0.0411
Echinococcus granulosus mitogen activated protein kinase 3 0.0109 0.0267 0.0418
Brugia malayi Cytochrome P450 family protein 0.0022 0.0014 0.0025
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0105 0.0204
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0045 0.0079 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0069 0.0151 0.0297
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0284 0.2286
Trichomonas vaginalis tubulin gamma chain, putative 0.0998 0.2869 0.5636
Loa Loa (eye worm) hypothetical protein 0.0097 0.0232 0.0456
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.001 0.0024
Schistosoma mansoni hypothetical protein 0.0051 0.0098 0.0152
Echinococcus granulosus sterol regulatory element binding protein 0.0089 0.0208 0.0325
Plasmodium vivax tubulin alpha chain, putative 0.133 0.3841 0.7543
Echinococcus granulosus methionine synthase reductase 0.002 0.0007 0.0008
Mycobacterium tuberculosis Cell division protein FtsZ 0.0436 0.1225 1
Schistosoma mansoni cpg binding protein 0.009 0.0213 0.0333
Echinococcus multilocularis Polycystic kidney disease protein 0.0165 0.0431 0.043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0172 0.0334
Trypanosoma cruzi p450 reductase, putative 0.0032 0.0043 0.0081
Leishmania major beta tubulin 0.1756 0.509 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.009 0.0213 0.0419
Schistosoma mansoni tubulin subunit beta 0.1756 0.509 0.7991
Plasmodium vivax tubulin alpha chain, putative 0.133 0.3841 0.7543
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0014 0.007
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0109 0.0267 0.0515
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0014 0.007
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0069 0.0151 0.0235
Echinococcus multilocularis lipoxygenase domain containing protein 0.0165 0.0431 0.043
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0014 0.007
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0061 0.0127 0.0247
Brugia malayi secreted modular calcium-binding protein 1 0.0061 0.0127 0.0247
Echinococcus granulosus raf serine:threonine protein kinase 0.0046 0.0082 0.0126
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0015 0.0021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0069 0.0151 0.0235
Loa Loa (eye worm) hypothetical protein 0.0259 0.0706 0.1386
Echinococcus granulosus alpha tubulin 0.133 0.3841 0.6029
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0045 0.0079
Echinococcus granulosus Tubulin beta 2C chain 0.1756 0.509 0.7991
Trypanosoma cruzi PAB1-binding protein , putative 0.0107 0.0261 0.051
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0045 0.0081 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0229 0.0447
Schistosoma mansoni nuclear hormone receptor 0.003 0.0036 0.0055
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.002 0.012
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0039 0.1854
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0063 0.0097
Onchocerca volvulus 0.009 0.021 0.0954
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0153 0.0299
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0039 0.0066
Loa Loa (eye worm) hypothetical protein 0.0061 0.0127 0.025
Echinococcus multilocularis tubulin alpha 1C chain 0.133 0.3841 0.384
Loa Loa (eye worm) tubulin alpha-3 chain 0.0797 0.228 0.448
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0284 0.0444
Entamoeba histolytica tubulin family protein 0.1756 0.509 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0063 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0024 0.0044
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0014 0.007
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0109 0.0267 0.0523
Schistosoma mansoni aryl hydrocarbon receptor 0.0206 0.0551 0.0864
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0229 0.0447
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0012 0.0017
Echinococcus granulosus Niemann Pick C1 protein 0.0207 0.0554 0.0867
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0015 0.0013
Onchocerca volvulus 0.0023 0.0015 0.0048
Plasmodium falciparum ataxin-2 like protein, putative 0.0107 0.0261 0.0502
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0015 0.0026
Loa Loa (eye worm) tubulin alpha chain 0.133 0.3841 0.7546
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0014 0.007
Schistosoma mansoni smdr2 0.0023 0.0015 0.0021
Brugia malayi jmjC domain containing protein 0.0068 0.0146 0.0284
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0284 0.0556

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 7.4 uM Inhibitory activity against Inducible nitric oxide synthase ChEMBL. No reference
IC50 (binding) = 7.4 uM Inhibitory activity against Inducible nitric oxide synthase ChEMBL. No reference
IC50 (binding) > 50 uM Inhibitory activity against Endothelial nitric oxide synthase ChEMBL. No reference
IC50 (binding) = 50 uM Inhibitory activity against Neuronal nitric oxide synthase ChEMBL. No reference
IC50 (binding) > 50 uM Inhibitory activity against Endothelial nitric oxide synthase ChEMBL. No reference
IC50 (binding) = 50 uM Inhibitory activity against Neuronal nitric oxide synthase ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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