Detailed information for compound 187375

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 284.356 | Formula: C16H20N4O+
  • H donors: 1 H acceptors: 2 LogP: 1.69 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc(C)cc(c1)N1CCN(C1=O)CC1=C(C)NC=[N+]1
  • InChi: 1S/C16H20N4O/c1-11-6-12(2)8-14(7-11)20-5-4-19(16(20)21)9-15-13(3)17-10-18-15/h6-8,10H,4-5,9H2,1-3H3,(H,17,18)/p+1
  • InChiKey: HLJSVGDJUCSCTA-UHFFFAOYSA-O  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide receptor 0.0068 0.029 0.0341
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0087 0.0175
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.012 0.0569 0.1244
Toxoplasma gondii ferredoxin, putative 0.0026 0.0068 0.0999
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0049 0.0049
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0001
Schistosoma mansoni cpg binding protein 0.0071 0.0307 0.0361
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0026 0.0068 0.0999
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0019 0.0023
Schistosoma mansoni neuroligin 3 (S09 family) 0.0013 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0053 0.021 0.3672
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0012 0.001
Echinococcus granulosus nuclear receptor nhr 48 0.0495 0.2556 0.3007
Echinococcus multilocularis multidrug resistance associated protein 1 0.0015 0.0007 0.0007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0054 0.0272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0055
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0023 0.0054 0.0099
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.003 0.0091 0.0107
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.005 0.0194 0.0228
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0068 0.029 0.0341
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0053 0.021 0.0381
Schistosoma mansoni opsin-like receptor 0.0068 0.029 0.0341
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0025 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0095 0.0224
Loa Loa (eye worm) hypothetical protein 0.1048 0.5497 1
Echinococcus multilocularis fmrfamide receptor 0.0068 0.029 0.029
Plasmodium falciparum LCCL domain-containing protein 0.0046 0.0174 0.3051
Schistosoma mansoni biogenic amine receptor 0.0068 0.029 0.0341
Brugia malayi CHD4 protein 0.0017 0.002 0.0037
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0048 0.0185 0.0337
Echinococcus multilocularis musashi 0.0063 0.0264 0.0264
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0047 0.0178 0.021
Echinococcus multilocularis g protein coupled receptor 0.0068 0.029 0.029
Echinococcus multilocularis thyroid hormone receptor alpha 0.1048 0.5497 0.5497
Echinococcus granulosus cytoplasmic intermediate filament protein 0.003 0.0091 0.0107
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0495 0.2556 0.4649
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0049 0.0089
Schistosoma mansoni sodium-dependent amino acid transporter 0.0048 0.0185 0.0218
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0068 0.029 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.0396 0.2034 0.4787
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0068 0.029 0.0527
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0141 0.0166
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0044 0.0164 0.0164
Echinococcus multilocularis orexin receptor type 2 0.0068 0.029 0.029
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.003 0.0091 0.0457
Onchocerca volvulus 0.0046 0.0174 0.0316
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0495 0.2556 0.4649
Trypanosoma cruzi polyprenyl synthase, putative 0.003 0.0091 0.0185
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0026 0.0068 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0228
Onchocerca volvulus 0.1048 0.5497 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.029 0.0341
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0495 0.2556 0.2556
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0001 0.0001
Brugia malayi follicle stimulating hormone receptor 0.0068 0.029 0.0527
Onchocerca volvulus 0.0068 0.029 0.0527
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0152 0.0771
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.029 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0275 0.1388 0.4971
Trichomonas vaginalis helicase, putative 0.0015 0.001 0.0024
Loa Loa (eye worm) SRC-1 0.0044 0.0164 0.0298
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0023 0.0035
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0027 0.0032
Onchocerca volvulus 0.0068 0.029 0.0527
Echinococcus multilocularis g-protein coupled receptor 0.0068 0.029 0.029
Trypanosoma brucei electron transfer protein, putative 0.0026 0.0068 0.0135
Echinococcus multilocularis Protein lozenge 0.0065 0.0273 0.0273
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0185 0.0337
Echinococcus multilocularis Ankyrin 0.0017 0.002 0.002
Schistosoma mansoni multidrug resistance protein 0.0015 0.0007 0.0009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.1048 0.5497 0.5497
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0185 0.0218
Brugia malayi cytoplasmic intermediate filament protein 0.0034 0.0109 0.0198
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0026 0.0068 0.0343
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0152 0.0179
Schistosoma mansoni nuclear receptor 0.0495 0.2556 0.3007
Echinococcus granulosus neuropeptides capa receptor 0.0068 0.029 0.0341
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.012 0.0569 0.1338
Echinococcus granulosus ubiquitin specific protease 41 0.0047 0.0178 0.021
Trichomonas vaginalis glucosylceramidase, putative 0.0396 0.2034 0.4787
Brugia malayi Nuclear hormone receptor-like 1 0.0554 0.2871 0.5222
Toxoplasma gondii endonuclease IV APN 0.0089 0.0404 0.5906
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0026 0.0068 0.0135
Loa Loa (eye worm) melatonin receptor type 1A 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Brugia malayi Nuclear hormone receptor family member nhr-14 0.1048 0.5497 1
Onchocerca volvulus Putative phospholipase D 0.0023 0.005 0.0092
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.004 0.0139
Echinococcus granulosus para nitrobenzyl esterase 0.0013 0.0001 0.0001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.1048 0.5497 0.5497
Trichomonas vaginalis glucosylceramidase, putative 0.0418 0.2147 0.5054
Brugia malayi Dopamine receptor protein 1 0.0068 0.029 0.0527
Schistosoma mansoni lamin 0.0063 0.0264 0.0311
Echinococcus granulosus tyrosine protein kinase Lyn 0.0044 0.0164 0.0193
Echinococcus granulosus intermediate filament protein 0.0063 0.0264 0.0311
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0062 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.1048 0.5497 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0019 0.0035
Mycobacterium ulcerans epimerase 0.0023 0.0054 0.0191
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0049 0.0172
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0158 0.0158
Brugia malayi nuclear hormone receptor family member nhr-6 0.0495 0.2556 0.4649
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.1048 0.5497 1
Echinococcus multilocularis somatostatin receptor 0.0068 0.029 0.029
Trichomonas vaginalis Ferredoxin 7 0.0026 0.0068 0.0161
Onchocerca volvulus 0.0013 0.0001 0.0001
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0105 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0118 0.0556 0.1012
Echinococcus granulosus biogenic amine 5HT receptor 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0101 0.0468 0.0851
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0087 0.0175
Loa Loa (eye worm) acetylcholinesterase 1 0.008 0.0352 0.064
Echinococcus multilocularis phospholipase D 0.0107 0.0496 0.0496
Onchocerca volvulus 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0264 0.0481
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0048 0.0185 0.0337
Echinococcus granulosus Ankyrin 0.0017 0.002 0.0023
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0813 0.4249 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.004 0.0197
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0023 0.0042
Loa Loa (eye worm) carboxylesterase 0.0013 0.0001 0.0001
Echinococcus granulosus nuclear factor of activated T cells 5 0.0086 0.0388 0.0457
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0089 0.0404 0.7101
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0068 0.029 0.029
Echinococcus granulosus RUN 0.0046 0.0174 0.0204
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0185 0.0218
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0141 0.0141
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0049 0.0244
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Brugia malayi Nuclear hormone receptor family member nhr-25 0.1048 0.5497 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0125 0.0594 0.108
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0027 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0396 0.2034 0.4787
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.002 0.0024
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.003 0.0087 0.0157
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0068 0.029 0.0341
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0246 0.1234 0.2245
Trichomonas vaginalis glucosylceramidase, putative 0.0418 0.2147 0.5054
Brugia malayi cytochrome P450 0.0021 0.004 0.0072
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0185 0.0218
Mycobacterium ulcerans oxidoreductase 0.0026 0.0068 0.0242
Echinococcus granulosus neuropeptide s receptor 0.0604 0.3136 0.369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0005 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.1048 0.5497 1
Echinococcus granulosus neuropeptide Y receptor 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Brugia malayi hypothetical protein 0.0048 0.0185 0.0337
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0068 0.029 0.0341
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0068 0.029 0.0341
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0185 0.271
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.029 0.029
Trypanosoma cruzi adrenodoxin precursor, putative 0.0026 0.0068 0.0135
Schistosoma mansoni biogenic amine receptor 0.0068 0.029 0.0341
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0027 0.0478
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0152 0.0771
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.0684 0.2447
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Plasmodium vivax cardiolipin synthetase, putative 0.0019 0.0032 0.0564
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0134 0.0642 0.3262
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0152 0.0543
Leishmania major ferredoxin 2fe-2s-like protein 0.0026 0.0068 0.0135
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Mycobacterium tuberculosis Possible oxygenase 0.0026 0.0068 0.0343
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.1048 0.5497 1
Echinococcus granulosus tm gpcr rhodopsin 0.0068 0.029 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.0189
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0027 0.0049
Onchocerca volvulus 0.0068 0.029 0.0527
Onchocerca volvulus 0.005 0.0194 0.0353
Onchocerca volvulus Protein ultraspiracle homolog 0.1048 0.5497 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0044 0.0164 0.0164
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0152 0.0179
Echinococcus granulosus phospholipase D1 0.0121 0.0571 0.0671
Echinococcus granulosus neuropeptide receptor 0.0068 0.029 0.0341
Trypanosoma cruzi adrenodoxin precursor, putative 0.0026 0.0068 0.0135
Echinococcus granulosus phospholipase D 0.0107 0.0496 0.0583
Loa Loa (eye worm) hypothetical protein 0.008 0.0352 0.064
Schistosoma mansoni multidrug resistance protein 0.0015 0.0007 0.0009
Echinococcus multilocularis neuroligin 0.0013 0.0001 0.0001
Onchocerca volvulus 0.028 0.1414 0.2572
Loa Loa (eye worm) TK protein kinase 0.0035 0.0118 0.0214
Schistosoma mansoni amine GPCR 0.0456 0.2354 0.2769
Leishmania major cytochrome p450-like protein 0.0041 0.0148 0.0312
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0123 0.1803
Schistosoma mansoni amine GPCR 0.0068 0.029 0.0341
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0185 0.271
Schistosoma mansoni RAR-like nuclear receptor 0.1048 0.5497 0.6468
Entamoeba histolytica ATP-binding cassette protein, putative 0.0015 0.0007 0.013
Brugia malayi Nuclear hormone receptor E75 0.0495 0.2556 0.4649
Loa Loa (eye worm) hypothetical protein 0.0079 0.0347 0.0631
Schistosoma mansoni aldehyde dehydrogenase 0.0142 0.0684 0.0804
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0554 0.2871 0.5222
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0068 0.029 0.0341
Mycobacterium ulcerans hypothetical protein 0.0023 0.0054 0.0191
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0087 0.1522
Onchocerca volvulus 0.0063 0.0264 0.0481
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.029 0.0341
Brugia malayi Carboxylesterase family protein 0.008 0.0352 0.064
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0044 0.0166 0.035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0068 0.029 0.0341
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.029 0.0341
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0539 0.279 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0023 0.0035
Leishmania major C-8 sterol isomerase-like protein 0.0864 0.4519 1
Schistosoma mansoni rab6-interacting 0.0046 0.0174 0.0204
Echinococcus granulosus farnesyl pyrophosphate synthase 0.012 0.0569 0.0669
Plasmodium falciparum ferredoxin, putative 0.0026 0.0068 0.1201
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0044 0.0166 0.2911
Giardia lamblia MRP-like ABC transporter 0.0015 0.0007 0.0011
Plasmodium vivax multidomain scavenger receptor, putative 0.0046 0.0174 0.3051
Trypanosoma brucei cytochrome P450, putative 0.0041 0.0148 0.0312
Schistosoma mansoni cellular tumor antigen P53 0.0116 0.0544 0.064
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0027 0.0398
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0238 0.0433
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.1048 0.5497 1
Trypanosoma cruzi Emopamil binding protein, putative 0.0161 0.0787 0.1727
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0185 0.0218
Trypanosoma brucei C-8 sterol isomerase, putative 0.0864 0.4519 1
Brugia malayi M-phase phosphoprotein, mpp8 0.0118 0.0556 0.1012
Echinococcus granulosus lamin dm0 0.0063 0.0264 0.0311
Brugia malayi neuropeptide F receptor 0.0068 0.029 0.0527
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0087 0.1522
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0044 0.0164 0.0193
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Loa Loa (eye worm) nuclear hormone receptor 0.0495 0.2556 0.4649
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0046 0.0085
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.003 0.0091 0.0185
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0185 0.0218
Loa Loa (eye worm) hypothetical protein 0.0516 0.267 0.4857
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.019
Schistosoma mansoni cytochrome P450 0.0021 0.004 0.0047
Brugia malayi hypothetical protein 0.0516 0.267 0.4857
Echinococcus granulosus neuropeptides capa receptor 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0118 0.0118
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.0277 0.0505
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0068 0.029 0.029
Brugia malayi Cytochrome P450 family protein 0.0021 0.004 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.019
Schistosoma mansoni farnesyl pyrophosphate synthase 0.012 0.0569 0.0669
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0012 0.001
Onchocerca volvulus 0.0042 0.0152 0.0277
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0044 0.0166 0.0301
Brugia malayi hypothetical protein 0.0118 0.0557 0.1013
Entamoeba histolytica hypothetical protein 0.0042 0.0152 0.2666
Onchocerca volvulus 0.0068 0.029 0.0527
Echinococcus multilocularis Polycystic kidney disease protein 0.0046 0.0174 0.0174
Loa Loa (eye worm) cytochrome P450 0.0021 0.004 0.0072
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0341 0.0739
Loa Loa (eye worm) hypothetical protein 0.0864 0.4519 0.822
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0554 0.2871 0.5222
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0185 0.0337
Echinococcus multilocularis cpg binding protein 0.0071 0.0307 0.0307
Echinococcus granulosus neuroligin 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0495 0.2556 0.4649
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0019 0.0023
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0001
Brugia malayi conserved hypotetical protein 0.0495 0.2556 0.4649
Brugia malayi SRC-1 0.0044 0.0164 0.0298
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0044 0.0166 0.2421
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.003 0.0091 0.1578
Echinococcus multilocularis g protein coupled receptor 0.0068 0.029 0.029
Brugia malayi ecdysone receptor 0.0495 0.2556 0.4649
Trypanosoma cruzi cardiolipin synthetase, putative 0.0042 0.0153 0.0323
Echinococcus granulosus dna polymerase kappa 0.0022 0.0049 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0396 0.2034 0.4787
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor 0.0068 0.029 0.029
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.012 0.0569 0.2035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.021 0.0493
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0089 0.0404 0.205
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.004 0.0197
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0185 0.271
Echinococcus multilocularis ecdysone induced protein 78C 0.1048 0.5497 0.5497
Plasmodium falciparum transporter, putative 0.0048 0.0185 0.3258
Loa Loa (eye worm) phospholipase D 0.0023 0.005 0.0092
Schistosoma mansoni hypothetical protein 0.004 0.014 0.0165
Mycobacterium ulcerans endonuclease IV 0.0089 0.0404 0.1444
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0048 0.0185 0.0218
Echinococcus multilocularis neuropeptide FF receptor 2 0.0068 0.029 0.029
Brugia malayi Serotonin receptor 0.0068 0.029 0.0527
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0068 0.029 0.0341
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0049 0.0856
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0117 0.0276
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus multilocularis tumor protein p63 0.079 0.4126 0.4126
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0123 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0043 0.0102
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0383 0.1966 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.1048 0.5497 0.6468
Echinococcus granulosus dna polymerase eta 0.0022 0.0049 0.0058
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0027 0.0027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0675 0.3515 0.3515
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1039 0.545 0.545
Loa Loa (eye worm) hypothetical protein 0.0048 0.0185 0.0337
Brugia malayi hypothetical protein 0.003 0.0087 0.0157
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.003 0.0091 0.0091
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0047 0.0178 0.0379
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0148 0.027
Echinococcus multilocularis allatostatin A receptor 0.0068 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0516 0.267 0.4857
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.1048 0.5497 1
Schistosoma mansoni multidrug resistance protein 0.0015 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.1048 0.5497 0.6468
Brugia malayi G protein-coupled receptor 0.0068 0.029 0.0527
Leishmania major solanesyl-diphosphate synthase, putative 0.003 0.0091 0.0185
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0053 0.021 0.0448
Schistosoma mansoni nuclear hormone receptor 0.0495 0.2556 0.3007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0152 0.0358
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0053 0.021 0.0448
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) carboxylesterase 0.008 0.0352 0.064
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0019 0.0032 0.0038
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Onchocerca volvulus 0.0516 0.267 0.4857
Brugia malayi hypothetical protein 0.0019 0.0032 0.0058
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0164 0.0193
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus multilocularis dro:myosuppressin receptor 0.0068 0.029 0.029
Trypanosoma brucei cardiolipin synthetase 0.0042 0.0153 0.0323
Brugia malayi GnHR receptor homolog 0.0068 0.029 0.0527
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0027 0.0032
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus granulosus nuclear receptor 2DBD gamma 0.1048 0.5497 0.6468
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0185 0.0185
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0089 0.0404 0.0734
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0135 0.0158
Loa Loa (eye worm) hypothetical protein 0.0062 0.0258 0.047
Brugia malayi Steroid receptor seven-up type 2 0.1048 0.5497 1
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.003 0.0091 0.159
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0068 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0185 0.0337
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0044 0.0166 0.0195
Onchocerca volvulus 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0029 0.0085 0.0155
Trichomonas vaginalis Ferredoxin 2 0.0026 0.0068 0.0161
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0068 0.029 0.0341
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0049 0.0244
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0027 0.0398
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0081 0.019
Entamoeba histolytica ATP-binding cassette protein, putative 0.0015 0.0007 0.013
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus granulosus tyrosine protein kinase Src42A 0.0044 0.0164 0.0193
Mycobacterium tuberculosis Conserved protein 0.0042 0.0152 0.0771
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0053 0.021 0.0247
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Brugia malayi Nuclear hormone receptor family member nhr-40 0.1048 0.5497 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0238 0.0433
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.1048 0.5497 1
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Brugia malayi G-protein coupled receptor 0.0068 0.029 0.0527
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0023 0.0035
Echinococcus multilocularis conserved hypothetical protein 0.081 0.423 0.423
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.004 0.0139
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.029 0.029
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0284 0.1436 0.2613
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0023 0.0054 0.0099
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0164 0.0193
Brugia malayi hypothetical protein 0.0042 0.0152 0.0277
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0015 0.0007 0.0108
Brugia malayi G-protein coupled receptor 0.0068 0.029 0.0527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Leishmania major DNA polymerase eta, putative 0.0022 0.0049 0.0092
Loa Loa (eye worm) G-protein coupled receptor 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0022 0.0049 0.0089
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0029 0.0085 0.0155
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.003 0.0091 0.0185
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0027 0.0027
Schistosoma mansoni multidrug resistance protein 0.0015 0.0007 0.0009
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0049 0.0058
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.003 0.0091 0.0457
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0081 0.019
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0019 0.0032 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0604 0.3137 0.7383
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0152 0.0771
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0058
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0068 0.029 0.029
Echinococcus multilocularis GPCR, family 2 0.0018 0.0027 0.0027
Schistosoma mansoni nuclear hormone receptor 0.1048 0.5497 0.6468
Echinococcus granulosus g protein coupled receptor 0.0068 0.029 0.0341
Schistosoma mansoni aldehyde dehydrogenase 0.0142 0.0684 0.0804
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0019 0.0019
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0049 0.0092
Schistosoma mansoni neuropeptide receptor 0.0068 0.029 0.0341
Brugia malayi Death domain containing protein 0.0017 0.0019 0.0035
Echinococcus multilocularis RUN 0.0046 0.0174 0.0174
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.0138 0.2015
Trypanosoma brucei cardiolipin synthetase, putative 0.0042 0.0153 0.0323
Loa Loa (eye worm) CYP4Cod1 0.0041 0.0148 0.027
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.012 0.0569 0.1338
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0554 0.2871 0.3378
Schistosoma mansoni loxhd1 0.0046 0.0174 0.0204
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0105 0.0486 0.0571
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0068 0.029 0.0527
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0134 0.0642 0.0755
Brugia malayi Polyprenyl synthetase family protein 0.003 0.0091 0.0165
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0554 0.2871 0.3378
Onchocerca volvulus Neuropeptide F receptor homolog 0.0068 0.029 0.0527
Chlamydia trachomatis endonuclease IV 0.0089 0.0404 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.0468 0.0851
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0123 0.0145
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0068 0.029 0.029
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.003 0.0091 0.0107
Brugia malayi beta-lactamase family protein 0.0042 0.0152 0.0277
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0026 0.0068 0.1201
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0045 0.0082
Brugia malayi CXXC zinc finger family protein 0.0067 0.0286 0.052
Schistosoma mansoni Tr4/Tr2 (homologue) 0.1048 0.5497 0.6468
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.029 0.0341
Schistosoma mansoni nuclear receptor nhr-48 0.0495 0.2556 0.3007
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0152 0.0358
Echinococcus granulosus phospholipase d3 0.0023 0.005 0.0059
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0068 0.029 0.029
Loa Loa (eye worm) serotonin transporter b 0.0284 0.1436 0.2613
Echinococcus granulosus 7TM GPCR rhodopsin 0.0068 0.029 0.0341
Brugia malayi SET domain containing protein 0.0016 0.0015 0.0027
Schistosoma mansoni biogenic amine (5HT) receptor 0.0068 0.029 0.0341
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.002 0.0023
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0152 0.0358
Brugia malayi Polyprenyl synthetase family protein 0.012 0.0569 0.1034
Echinococcus granulosus g protein coupled receptor 0.0068 0.029 0.0341
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.029 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0228
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0047 0.0178 0.021
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.1048 0.5497 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0068 0.029 0.0341
Brugia malayi Uncoordinated protein 44 0.0017 0.0019 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-19 0.1048 0.5497 1
Schistosoma mansoni glutathione synthetase 0.003 0.0091 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0152 0.0321
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.004 0.0139
Echinococcus granulosus thyroid hormone receptor alpha 0.0495 0.2556 0.3007
Echinococcus multilocularis neuropeptide Y receptor 0.0068 0.029 0.029
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0044 0.0166 0.0166
Brugia malayi sulfakinin receptor protein 0.0068 0.029 0.0527
Echinococcus granulosus FTZ F1 alpha 0.1048 0.5497 0.6468
Schistosoma mansoni phospholipase D 0.0121 0.0571 0.0671
Loa Loa (eye worm) hypothetical protein 0.0415 0.2133 0.3879
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0141 0.0141
Brugia malayi Cytochrome P450 family protein 0.0041 0.0148 0.027
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0241 0.121 0.4334
Brugia malayi Phospholipase D. Active site motif family protein 0.0042 0.0153 0.0278
Brugia malayi larval opioid receptor 0.0068 0.029 0.0527
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0068 0.029 0.0527
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.1048 0.5497 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.1048 0.5497 0.6468
Loa Loa (eye worm) steroid hormone receptor 0.1048 0.5497 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0081 0.019
Echinococcus multilocularis neuropeptide Y receptor 0.0068 0.029 0.029
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0604 0.3137 0.5706
Echinococcus granulosus fmrfamide receptor 0.0068 0.029 0.0341
Trypanosoma brucei unspecified product 0.0022 0.0049 0.0092
Schistosoma mansoni lipoxygenase 0.0119 0.0562 0.0661
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0041 0.0148 0.0529
Echinococcus granulosus carboxylesterase 5A 0.008 0.0352 0.0414
Leishmania major cytochrome p450-like protein 0.0021 0.004 0.0071
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.002 0.0024
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.004 0.0139
Echinococcus granulosus lipoxygenase domain containing protein 0.0046 0.0174 0.0204
Mycobacterium ulcerans beta-lactamase 0.0042 0.0152 0.0543
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0081 0.019
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0053 0.021 0.021
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0048 0.0185 0.4121
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0027 0.0478
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0185 0.3258
Toxoplasma gondii ferodoxin FD 0.0026 0.0068 0.0999
Brugia malayi photoreceptor-specific nuclear receptor 0.1048 0.5497 1
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0275 0.1388 0.7058
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0044 0.0166 0.039
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0185 0.0218
Loa Loa (eye worm) carboxylesterase 0.0013 0.0001 0.0001
Treponema pallidum sodium- and chloride- dependent transporter 0.0284 0.1436 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0049 0.0092
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0068 0.029 0.0341
Echinococcus granulosus serotonin transporter 0.0284 0.1436 0.169
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.029 0.0341
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0023 0.0054 0.0191
Mycobacterium tuberculosis Conserved protein 0.0042 0.0152 0.0771
Echinococcus granulosus lamin 0.0063 0.0264 0.0311
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.029 0.029
Schistosoma mansoni neuropeptide F-like receptor 0.0068 0.029 0.0341
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0152 0.0152
Mycobacterium ulcerans lipase LipD 0.0042 0.0152 0.0543
Trypanosoma brucei unspecified product 0.0016 0.0012 0.001
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0053 0.021 0.0247
Brugia malayi Nuclear hormone receptor family member nhr-49 0.1048 0.5497 1
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0026 0.0068 0.0242
Schistosoma mansoni opsin-like receptor 0.0068 0.029 0.0341
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0185 0.0218
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0152 0.0179
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0089 0.0404 0.7101
Onchocerca volvulus 0.0026 0.0068 0.0124
Echinococcus granulosus neuropeptide Y receptor 0.0068 0.029 0.0341
Brugia malayi Melatonin receptor type 1A 0.0068 0.029 0.0527
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0026 0.0068 0.0124
Echinococcus granulosus GPCR family 2 0.0018 0.0027 0.0032
Brugia malayi multidrug resistance related protein 1 0.0015 0.0007 0.0013
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0048 0.0185 0.0185
Leishmania major hypothetical protein, conserved 0.003 0.0087 0.0175
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0087 0.1266
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0864 0.4519 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.004 0.014 0.0255
Schistosoma mansoni amine GPCR 0.0068 0.029 0.0341
Brugia malayi ORL1-like opioid receptor 0.0068 0.029 0.0527
Entamoeba histolytica ATP-binding cassette protein, putative 0.0015 0.0007 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Echinococcus granulosus BC026374 protein S09 family 0.0013 0.0001 0.0001
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0027 0.0032
Echinococcus granulosus biogenic amine 5HT receptor 0.0068 0.029 0.0341
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0495 0.2556 0.3007
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0134 0.0642 0.0642
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0047 0.0178 0.3127
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0068 0.029 0.029
Echinococcus multilocularis phospholipase d3 0.0023 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Treponema pallidum hypothetical protein 0.0132 0.0632 0.4019
Loa Loa (eye worm) CXXC zinc finger family protein 0.0067 0.0286 0.052
Loa Loa (eye worm) TK protein kinase 0.004 0.0141 0.0257
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0042 0.0153 0.0321
Echinococcus granulosus multidrug resistance associated protein 1 0.0015 0.0007 0.0009
Brugia malayi protein-tyrosine kinase 0.004 0.0141 0.0257
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0604 0.3137 0.5706
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0081 0.019
Echinococcus granulosus tm gpcr rhodopsin 0.0675 0.3515 0.4135
Onchocerca volvulus 0.0048 0.0185 0.0337
Entamoeba histolytica hypothetical protein 0.0042 0.0152 0.2666
Brugia malayi Nuclear hormone receptor family member nhr-25 0.1048 0.5497 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.1048 0.5497 0.6468
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0025 0.0025
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0049 0.0092
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0068 0.029 0.0527
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.1048 0.5497 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0495 0.2556 0.3007
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.004 0.0139
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.004 0.0139
Loa Loa (eye worm) hypothetical protein 0.1048 0.5497 1
Echinococcus granulosus geminin 0.0197 0.0978 0.1151
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0068 0.029 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Echinococcus multilocularis ubiquitin specific protease 41 0.0047 0.0178 0.0178
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0155 0.0754 0.3833
Echinococcus granulosus Polycystic kidney disease protein 0.0046 0.0174 0.0204
Onchocerca volvulus 0.0042 0.0152 0.0277
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0277
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0179 0.021
Echinococcus granulosus dnaJ subfamily B 0.0956 0.5009 0.5893
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.1048 0.5497 0.6468
Schistosoma mansoni lamin 0.0063 0.0264 0.0311
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0178 0.042
Schistosoma mansoni hypothetical protein 0.0042 0.0152 0.0179
Echinococcus multilocularis 0.0021 0.004 0.004
Echinococcus granulosus multidrug resistance associated protein 7 0.0015 0.0007 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.1048 0.5497 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0053 0.021 0.0448
Schistosoma mansoni cpg binding protein 0.0071 0.0307 0.0361
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0049 0.0172
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0158 0.0186
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0019 0.0035
Onchocerca volvulus 0.0013 0.0001 0.0001
Brugia malayi hypothetical protein 0.0495 0.2556 0.4649
Mycobacterium leprae Probable lipase LipE 0.0042 0.0152 0.3094
Echinococcus multilocularis transcription factor Dp 1 0.0045 0.0168 0.0168
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.003 0.0091 0.0091
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0495 0.2556 0.4649
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0063 0.0264 0.0481
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Schistosoma mansoni steroid hormone receptor ad4bp 0.1048 0.5497 0.6468
Mycobacterium ulcerans oxygenase 0.0026 0.0068 0.0242
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus multilocularis phospholipase D1 0.0121 0.0571 0.0571
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0044 0.0166 0.035
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Brugia malayi Cytochrome P450 family protein 0.0041 0.0148 0.027
Schistosoma mansoni myosin xvIII 0.0068 0.029 0.0341
Brugia malayi steroid hormone receptor 0.1048 0.5497 1
Giardia lamblia [2Fe-2S] ferredoxin 0.0026 0.0068 0.1095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0495 0.2556 0.2556
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0053 0.021 0.0448
Echinococcus granulosus microtubule associated protein 2 0.1614 0.85 1
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.012 0.0569 0.2035
Brugia malayi nuclear hormone receptor 0.0495 0.2556 0.4649
Schistosoma mansoni biogenic amine (5HT) receptor 0.0068 0.029 0.0341
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-19 0.1048 0.5497 1
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.004 0.0139
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0134 0.0642 0.2298
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0148 0.027
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0161 0.0787 0.1727
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.0684 0.2447
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0027 0.0049
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0141 0.0141
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.003 0.0091 0.0107
Onchocerca volvulus 0.0284 0.1436 0.2613
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.012 0.0569 0.2889
Schistosoma mansoni lozenge 0.0065 0.0273 0.0322
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0152 0.0771
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Chlamydia trachomatis ferredoxin 0.0026 0.0068 0.0975
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0026 0.0068 0.0135
Brugia malayi Intermediate filament tail domain containing protein 0.0063 0.0264 0.0481
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.003 0.0091 0.1595
Onchocerca volvulus 0.0118 0.0556 0.1012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.029 0.029
Echinococcus granulosus sex peptide receptor 0.0068 0.029 0.0341
Plasmodium vivax SET domain protein, putative 0.0036 0.0123 0.2168
Giardia lamblia ABC transporter, putative 0.0015 0.0007 0.0011
Echinococcus multilocularis geminin 0.0197 0.0978 0.0978
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.002 0.0037
Schistosoma mansoni rab6-interacting 0.0046 0.0174 0.0204
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Leishmania major polyprenyl synthase, putative 0.003 0.0091 0.0185
Onchocerca volvulus 0.0013 0.0001 0.0001
Schistosoma mansoni cpg binding protein 0.0067 0.0286 0.0337
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0277
Echinococcus granulosus transcription factor Dp 1 0.0045 0.0168 0.0197
Onchocerca volvulus 0.0161 0.0787 0.1431
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0053 0.021 0.0448
Brugia malayi Nuclear hormone receptor-like 1 0.0554 0.2871 0.5222
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0023 0.005 0.0095
Loa Loa (eye worm) neuropeptide F receptor 0.0068 0.029 0.0527
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0383 0.1966 0.7044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0178 0.042
Loa Loa (eye worm) G-protein coupled receptor 0.0068 0.029 0.0527
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0043 0.0102
Giardia lamblia GTOR 0.0053 0.021 0.3609
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0015 0.0007 0.0013
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0495 0.2556 0.4649
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.004 0.0197
Trichomonas vaginalis glucosylceramidase, putative 0.0604 0.3137 0.7383
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0068 0.029 0.0527
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0026 0.0068 0.6178
Echinococcus multilocularis fmrfamide receptor 0.0068 0.029 0.029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.1048 0.5497 0.5497
Brugia malayi nuclear receptor NHR-88 0.1048 0.5497 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0185 0.0185
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.003 0.0091 1
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0044 0.0166 0.0301
Schistosoma mansoni sodium/chloride dependent transporter 0.0284 0.1436 0.169
Echinococcus granulosus retinoic acid receptor rxr beta a 0.1163 0.6107 0.7185
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0495 0.2556 0.3007
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0185 0.0218
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Brugia malayi Dopamine receptor protein 2 0.0068 0.029 0.0527
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.003 0.0091 0.0457
Leishmania major hypothetical protein, conserved 0.0026 0.0068 0.0135
Mycobacterium ulcerans electron transfer protein FdxB 0.0026 0.0068 0.0242
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.003 0.0091 1
Onchocerca volvulus 0.0495 0.2556 0.4649
Brugia malayi nuclear hormone receptor family member odr-7 0.0495 0.2556 0.4649
Schistosoma mansoni tyrosine kinase 0.0044 0.0164 0.0193
Schistosoma mansoni hypothetical protein 0.0068 0.029 0.0341
Loa Loa (eye worm) polyprenyl synthetase 0.012 0.0569 0.1034
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.004 0.0197
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.1048 0.5497 1
Echinococcus granulosus neuropeptide receptor A26 0.0604 0.3136 0.369
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0185 0.0218
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.004 0.0197
Onchocerca volvulus 0.0068 0.029 0.0527
Schistosoma mansoni histamine h1 receptor 0.0068 0.029 0.0341
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0554 0.2871 0.2871
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0001
Giardia lamblia DINP protein human, muc B family 0.0022 0.0049 0.0749
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.029 0.0341
Echinococcus granulosus 7tm_1 domain containing protein 0.0068 0.029 0.0341
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0025 0.0029
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0068 0.029 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.029 0.0341
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0027 0.0049
Brugia malayi Dopamine receptor 0.0068 0.029 0.0527
Echinococcus multilocularis neuropeptides capa receptor 0.0068 0.029 0.029
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0026 0.0068 0.0975
Trichomonas vaginalis glucosylceramidase, putative 0.0604 0.3137 0.7383
Loa Loa (eye worm) hypothetical protein 0.0046 0.0174 0.0316
Echinococcus granulosus tyrosine kinase 0.004 0.0141 0.0166
Schistosoma mansoni hypothetical protein 0.0068 0.029 0.0341
Trypanosoma cruzi solanesyl-diphosphate synthase 0.003 0.0091 0.0185
Echinococcus multilocularis neuropeptide receptor 0.0068 0.029 0.029
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.004 0.0197
Schistosoma mansoni neuropeptide receptor 0.0068 0.029 0.0341
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0026 0.0068 0.0124
Entamoeba histolytica phospholipase D, putative 0.0121 0.0571 1
Trichomonas vaginalis glucosylceramidase, putative 0.0396 0.2034 0.4787
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0077 0.0341 0.0401
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.029 0.029
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Schistosoma mansoni tyrosine kinase 0.0044 0.0164 0.0193
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0034 0.0109 0.0198
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.003 0.0091 0.0091
Brugia malayi Doublecortin family protein 0.0046 0.0174 0.0316
Echinococcus multilocularis serotonin receptor 0.0068 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0047 0.0178 0.0324
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0152 0.0358
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0135 0.0135
Mycobacterium ulcerans oxidoreductase 0.0026 0.0068 0.0242
Onchocerca volvulus 0.0048 0.0185 0.0337
Brugia malayi Pre-SET motif family protein 0.0036 0.0123 0.0224
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0134 0.0642 0.0755
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.003 0.0091 0.0091
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0027 0.0044
Schistosoma mansoni BC026374 protein (S09 family) 0.0013 0.0001 0.0001
Echinococcus multilocularis dna polymerase eta 0.0022 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0123 0.0224
Leishmania major hypothetical protein, conserved 0.0161 0.0787 0.1727
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.003 0.0091 0.159
Brugia malayi nuclear hormone receptor 0.1048 0.5497 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Treponema pallidum quinoline 2-oxidoreductase 0.0129 0.0615 0.3898
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.0684 0.2447
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0081 0.019
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0341 0.0739
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0042 0.0153 0.0321
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0152 0.0358
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.012 0.0569 0.1338
Brugia malayi Protein kinase domain containing protein 0.0017 0.0019 0.0035
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0044 0.0164 0.0164
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0161 0.0787 0.1727
Giardia lamblia Multidrug resistance-associated protein 1 0.0015 0.0007 0.0011
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0053 0.021 0.0448
Brugia malayi hypothetical protein 0.0019 0.0031 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0123 0.0145
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.003 0.0091 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) norepinephrine transporter 0.0284 0.1436 0.2613
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0027 0.0044
Treponema pallidum hypothetical protein 0.0109 0.0508 0.3099
Loa Loa (eye worm) hypothetical protein 0.002 0.0038 0.007
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0864 0.4519 0.822
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.004 0.0071
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0027 0.0134
Trypanosoma cruzi Emopamil binding protein, putative 0.0161 0.0787 0.1727
Brugia malayi Serotonin receptor 0.0608 0.3156 0.5742
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0185 0.0337
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0143 0.0336
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0044 0.0166 0.039
Loa Loa (eye worm) hypothetical protein 0.0442 0.2275 0.4139
Brugia malayi nuclear receptor RXR 0.0554 0.2871 0.5222
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.003 0.0091 0.0322
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.1048 0.5497 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0185 0.0337
Mycobacterium ulcerans hypothetical protein 0.0042 0.0152 0.0543
Echinococcus multilocularis lamin dm0 0.0063 0.0264 0.0264
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0152 0.3094
Echinococcus multilocularis acetylcholinesterase 0.008 0.0352 0.0352
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0026 0.0068 0.0124
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0152 0.0358
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0049 0.0092
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0044 0.0164 0.0164
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0068 0.029 0.029
Trypanosoma brucei Emopamil binding protein, putative 0.0161 0.0787 0.1727
Schistosoma mansoni microtubule-associated protein tau 0.1614 0.85 1
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0068 0.0135
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0277
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0178 0.0379
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0123 0.0123
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.004 0.0139
Echinococcus granulosus neuropeptide receptor 0.0068 0.029 0.0341
Onchocerca volvulus 0.0042 0.0152 0.0277
Schistosoma mansoni retinoid-x-receptor (RXR) 0.1048 0.5497 0.6468
Schistosoma mansoni neuropeptide receptor 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0089 0.0404 0.0734
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.004 0.0197
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.004 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.019
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0164 0.0164
Echinococcus multilocularis sex peptide receptor 0.0068 0.029 0.029
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.029 0.0341
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0152 0.0179
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.004 0.0139
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0025 0.0025
Brugia malayi AKH receptor 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.1048 0.5497 1
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.004 0.0197
Onchocerca volvulus 0.0068 0.029 0.0527
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0152 0.0543
Brugia malayi Pre-SET motif family protein 0.0246 0.1234 0.2245
Entamoeba histolytica protein kinase, putative 0.0035 0.0118 0.2064
Mycobacterium tuberculosis Probable oxidoreductase 0.0026 0.0068 0.0343
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0087 0.1522
Trichomonas vaginalis aldehyde oxidase, putative 0.0813 0.4249 1
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.012 0.0569 1
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0415 0.2133 0.3879
Loa Loa (eye worm) hypothetical protein 0.1048 0.5497 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0142 0.0684 0.3474
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0019 0.0035
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0158 0.0287
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.004 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Schistosoma mansoni hypothetical protein 0.0061 0.0252 0.0296
Schistosoma mansoni hypothetical protein 0.0197 0.0978 0.1151
Brugia malayi hypothetical protein 0.0046 0.0174 0.0316
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni coup transcription factor 0.1048 0.5497 0.6468
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0178 0.021
Entamoeba histolytica hypothetical protein 0.0042 0.0152 0.2666
Brugia malayi intermediate filament protein 0.0063 0.0264 0.0481
Loa Loa (eye worm) hypothetical protein 0.0415 0.2133 0.3879
Loa Loa (eye worm) hypothetical protein 0.0046 0.0174 0.0316
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.008 0.0352 0.0414
Echinococcus granulosus serotonin receptor 0.0068 0.029 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0152 0.0358
Echinococcus granulosus G protein coupled receptor 139 0.0068 0.029 0.0341
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0049 0.0115
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0185 0.0218
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0023 0.0035
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0013 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0097 0.0228
Schistosoma mansoni hypothetical protein 0.0018 0.0027 0.0032
Schistosoma mansoni nuclear receptor 0.0495 0.2556 0.3007
Trichomonas vaginalis esterase, putative 0.0042 0.0152 0.0358
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0048 0.0185 0.0185
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0155 0.0754 0.27
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0095 0.0224
Schistosoma mansoni acetylcholinesterase 0.0013 0.0001 0.0001
Brugia malayi tailless protein 0.0495 0.2556 0.4649
Onchocerca volvulus 0.0067 0.0286 0.052
Echinococcus multilocularis neuropeptide s receptor 0.0604 0.3136 0.3136
Loa Loa (eye worm) hypothetical protein 0.0284 0.1436 0.2613
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0027 0.0027
Entamoeba histolytica ATP-binding cassette protein, putative 0.0015 0.0007 0.013
Trichomonas vaginalis Ferredoxin 3 0.0026 0.0068 0.0161
Trichomonas vaginalis glucosylceramidase, putative 0.0396 0.2034 0.4787
Loa Loa (eye worm) DR-78 0.0495 0.2556 0.4649
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0202 0.1001 0.1178
Onchocerca volvulus 0.0068 0.029 0.0527
Brugia malayi putative neuropeptide receptor 0.0068 0.029 0.0527
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.004 0.0579
Echinococcus multilocularis serotonin transporter 0.0284 0.1436 0.1436
Trichomonas vaginalis set domain proteins, putative 0.0279 0.1413 0.3327
Brugia malayi Carboxylesterase family protein 0.008 0.0352 0.064
Brugia malayi G protein-coupled receptor F59B2.13 0.0068 0.029 0.0527
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.004 0.0071
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0179 0.021
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0077 0.0341 0.062
Loa Loa (eye worm) runx1 0.0065 0.0273 0.0497
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0178 0.0379
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.1048 0.5497 0.6468
Mycobacterium ulcerans electron transfer protein 0.0026 0.0068 0.0242
Echinococcus multilocularis neuropeptides capa receptor 0.0068 0.029 0.029
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0049 0.0058
Trypanosoma brucei unspecified product 0.0016 0.0012 0.001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0023 0.0042
Schistosoma mansoni hypothetical protein 0.0018 0.0027 0.0032
Schistosoma mansoni hypothetical protein 0.0068 0.029 0.0341
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0054 0.0401
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0068 0.029 0.0341
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0813 0.4249 1
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0044 0.0166 0.0195
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0148 0.0312
Schistosoma mansoni trans-prenyltransferase 0.003 0.0091 0.0107
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.012 0.0569 0.0569
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0027 0.0049
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0049 0.0092
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0026 0.0068 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0047 0.0085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0081 0.019
Echinococcus multilocularis lipoxygenase domain containing protein 0.0046 0.0174 0.0174
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.004 0.0139
Echinococcus multilocularis FTZ F1 alpha 0.1048 0.5497 0.5497
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0152 0.0179
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0027 0.0044
Schistosoma mansoni biogenic amine receptor 0.0068 0.029 0.0341
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0068 0.029 0.0341
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.004 0.0139
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0025 0.0029
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.004 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.029 0.0341
Leishmania major ferredoxin, 2fe-2s-like protein 0.0026 0.0068 0.0135
Toxoplasma gondii ABC1 family protein 0.0042 0.0152 0.2227
Trypanosoma brucei farnesyl pyrophosphate synthase 0.012 0.0569 0.1244
Echinococcus granulosus alpha 1A adrenergic receptor 0.0068 0.029 0.0341
Echinococcus multilocularis lamin 0.0063 0.0264 0.0264
Brugia malayi RE15519p 0.0068 0.029 0.0527
Schistosoma mansoni thyroid hormone receptor 0.1048 0.5497 0.6468
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0012 0.001
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0134 0.0642 0.1168
Echinococcus multilocularis para nitrobenzyl esterase 0.0013 0.0001 0.0001
Schistosoma mansoni netrin receptor unc5 0.0017 0.0019 0.0023
Loa Loa (eye worm) hypothetical protein 0.008 0.0352 0.064
Onchocerca volvulus 0.0068 0.029 0.0527
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Onchocerca volvulus 0.0068 0.029 0.0527
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0152 0.0152
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Echinococcus granulosus tumor protein p63 0.079 0.4126 0.4854
Schistosoma mansoni nuclear hormone receptor 0.0495 0.2556 0.3007
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0077 0.0341 0.0341
Entamoeba histolytica multidrug resistance protein, putative 0.0015 0.0007 0.013
Brugia malayi Cytochrome P450 family protein 0.0066 0.0277 0.0505
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0047 0.0178 0.0324
Toxoplasma gondii hypothetical protein 0.0048 0.0185 0.271
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0027 0.0044
Schistosoma mansoni retinoic acid receptor RXR 0.1163 0.6107 0.7185
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0019 0.0032 0.0564
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.029 0.0341
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0068 0.029 0.029
Brugia malayi ABC transporter transmembrane region family protein 0.0015 0.0007 0.0013
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0086 0.0388 0.0388
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0123 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-41 0.1048 0.5497 1
Onchocerca volvulus 0.0063 0.0264 0.0481
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0152 0.0321
Echinococcus granulosus hypothetical protein 0.0878 0.459 0.54
Brugia malayi neuropeptide F receptor 0.0068 0.029 0.0527
Schistosoma mansoni growth hormone secretagogue receptor 0.0068 0.029 0.0341
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0152 0.0321
Loa Loa (eye worm) intermediate filament protein 0.0063 0.0264 0.0481
Brugia malayi beta-lactamase 0.0042 0.0152 0.0277
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0027 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0048 0.0185 0.0218
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0044 0.0164 0.0164
Onchocerca volvulus 0.0068 0.029 0.0527
Schistosoma mansoni adenoreceptor 0.0068 0.029 0.0341
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.029 0.029
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0044 0.0166 0.2901
Brugia malayi Tachykinin-like peptides receptor 99D 0.0068 0.029 0.0527
Echinococcus multilocularis neuropeptide receptor A26 0.0604 0.3136 0.3136
Toxoplasma gondii histone lysine methyltransferase SET1 0.0129 0.0612 0.8954
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0077 0.0341 0.0739
Echinococcus granulosus tm gpcr rhodopsin 0.1039 0.545 0.6412
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0068 0.029 0.0527
Leishmania major hypothetical protein, conserved 0.0042 0.0152 0.0321
Echinococcus multilocularis dnaJ subfamily B 0.0956 0.5009 0.5009
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0048 0.0185 0.0337
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0284 0.1436 0.2613
Echinococcus multilocularis carboxylesterase 5A 0.008 0.0352 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0178 0.042
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.004 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.0604 0.3137 0.7383
Loa Loa (eye worm) neuropeptide F receptor 0.0068 0.029 0.0527
Schistosoma mansoni intermediate filament proteins 0.0063 0.0264 0.0311
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0284 0.1436 0.169
Onchocerca volvulus Bile acid receptor homolog 0.1048 0.5497 1
Onchocerca volvulus 0.0048 0.0185 0.0337
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.004 0.0139
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0495 0.2556 0.3007
Toxoplasma gondii hypothetical protein 0.0048 0.0185 0.271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.021 0.0493
Echinococcus multilocularis microtubule associated protein 2 0.1614 0.85 0.85
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.004 0.0139
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0068 0.029 0.0527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0055
Plasmodium vivax amine transporter, putative 0.0048 0.0185 0.3258
Loa Loa (eye worm) doublecortin family protein 0.0046 0.0174 0.0316
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0019 0.0032 0.0564
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0044 0.0166 0.0301
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0152 0.0277
Loa Loa (eye worm) hypothetical protein 0.0048 0.0185 0.0337
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.029 0.0341
Echinococcus multilocularis g protein coupled receptor 0.0068 0.029 0.029
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0047 0.0178 0.3055
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0155 0.0754 0.27
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0166
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus granulosus Adrenodoxin mitochondrial 0.0026 0.0068 0.008
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0105 0.0486 0.0571
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0023 0.0035
Brugia malayi hypothetical protein 0.0554 0.2871 0.5222
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0143 0.0336
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0178 0.0178
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.004 0.0197
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0044 0.0166 0.0301
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.004 0.0197
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0026 0.0068 0.0242
Echinococcus multilocularis nuclear receptor nhr 48 0.0495 0.2556 0.2556
Trypanosoma cruzi target of rapamycin kinase 3 0.0042 0.0153 0.0321
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0178 0.0379
Onchocerca volvulus 0.0046 0.0174 0.0316
Brugia malayi isocitrate dehydrogenase 0.0018 0.0027 0.0049
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0077 0.0341 0.5974
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0185 0.0218
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0152 0.0771
Entamoeba histolytica hypothetical protein 0.0042 0.0152 0.2666
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.1048 0.5497 0.6468
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0158 0.0287
Trypanosoma cruzi cardiolipin synthetase, putative 0.0042 0.0153 0.0323
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0068 0.029 0.0527
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0238 0.0433
Loa Loa (eye worm) hypothetical protein 0.0554 0.2871 0.5222
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0101 0.0468 0.8201
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0185 0.0218
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0178 0.0178
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.003 0.0091 0.0322
Loa Loa (eye worm) hypothetical protein 0.0023 0.0054 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.029 0.0341
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0185 0.0218
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0068 0.029 0.0341
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0049 0.0089
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0142 0.0684 0.0804
Schistosoma mansoni amine GPCR 0.0068 0.029 0.0341
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0027 0.0027
Echinococcus granulosus tyrosine protein kinase Src64B 0.0044 0.0164 0.0193
Onchocerca volvulus 0.0013 0.0001 0.0001
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0019 0.0032 0.0564
Onchocerca volvulus 0.0068 0.029 0.0527
Trichomonas vaginalis glucosylceramidase, putative 0.0604 0.3137 0.7383
Loa Loa (eye worm) hypothetical protein 0.0037 0.0128 0.0232
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0053 0.021 0.3672
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Loa Loa (eye worm) hypothetical protein 0.0554 0.2871 0.5222
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.012 0.0569 0.1244
Trichomonas vaginalis glucosylceramidase, putative 0.0396 0.2034 0.4787
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0036
Brugia malayi Nuclear hormone receptor E75 0.0495 0.2556 0.4649
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0185 0.0337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.0189
Leishmania major cardiolipin synthetase, putative 0.0019 0.0032 0.0055
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0068 0.029 0.0341
Brugia malayi hypothetical protein 0.0554 0.2871 0.5222
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0495 0.2556 0.3007
Brugia malayi Phospholipase d protein 1 0.0121 0.0571 0.1038
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.1048 0.5497 0.6468
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.004 0.0139
Loa Loa (eye worm) beta-lactamase 0.0042 0.0152 0.0277
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.003 0.0091 0.0107
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0068 0.029 0.0341
Echinococcus multilocularis multidrug resistance associated protein 7 0.0015 0.0007 0.0007
Echinococcus multilocularis G-protein coupled receptor, putative 0.0068 0.029 0.029
Echinococcus multilocularis acetylcholinesterase 0.008 0.0352 0.0352
Loa Loa (eye worm) phosphatidylinositol 3 0.0053 0.021 0.0381
Entamoeba histolytica hypothetical protein 0.0015 0.0007 0.013
Brugia malayi ecdysteroid receptor 0.1048 0.5497 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.029 0.029
Echinococcus granulosus acetylcholinesterase 0.008 0.0352 0.0414
Brugia malayi nuclear receptor NHR-88 0.0495 0.2556 0.4649
Leishmania major DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.014 0.0255
Schistosoma mansoni hypothetical protein 0.0021 0.004 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.004 0.0197
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0118 0.0139
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0554 0.2871 0.3378
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0023 0.0028
Brugia malayi Phospholipase D. Active site motif family protein 0.0023 0.005 0.0092
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.1048 0.5497 0.5497
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.012 0.0569 1
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.003 0.0091 0.1595
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0089 0.0404 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0609 0.3166 0.3166
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0047 0.0047
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0047 0.0055
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0048 0.0185 0.0185
Toxoplasma gondii aldehyde dehydrogenase 0.0142 0.0684 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0049 0.0049
Schistosoma mansoni lipoxygenase 0.0202 0.1001 0.1178
Loa Loa (eye worm) hypothetical protein 0.0116 0.0544 0.0989
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0087 0.0175
Echinococcus granulosus neuropeptide FF receptor 2 0.0068 0.029 0.0341
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0081 0.019
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0161 0.0787 0.1727
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0105 0.0486 0.0571
Brugia malayi putative neuropeptide receptor NPR1 0.0068 0.029 0.0527
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0495 0.2556 0.2556
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.004 0.0197
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0019 0.0023
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Schistosoma mansoni thyroid hormone receptor 0.1048 0.5497 0.6468
Loa Loa (eye worm) nuclear receptor NHR-67 0.0495 0.2556 0.4649
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0268 0.1353 0.688
Echinococcus granulosus g-protein coupled receptor 0.0068 0.029 0.0341
Entamoeba histolytica phospholipase D, putative 0.0121 0.0571 1
Echinococcus granulosus ferredoxin 0.0026 0.0068 0.008
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0032
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0383 0.1966 0.7044
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0152 0.0771
Brugia malayi nuclear receptor RXR 0.0495 0.2556 0.4649
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0134 0.0642 0.2298
Trypanosoma cruzi adrenodoxin precursor, putative 0.0026 0.0068 0.0135
Echinococcus granulosus cpg binding protein 0.0071 0.0307 0.0361
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0049 0.0092
Onchocerca volvulus 0.0118 0.0556 0.1012
Brugia malayi hypothetical protein 0.0013 0.0001 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.1048 0.5497 1
Schistosoma mansoni hypothetical protein 0.0197 0.0978 0.1151
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0013 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.012 0.0569 0.8317
Schistosoma mansoni hypothetical protein 0.0018 0.0027 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0169 0.0397
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Trypanosoma cruzi polyprenyl synthase, putative 0.003 0.0091 0.0185
Echinococcus granulosus somatostatin receptor 0.0068 0.029 0.0341
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.003 0.0091 0.1405
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0023 0.0028
Echinococcus multilocularis BC026374 protein (S09 family) 0.0013 0.0001 0.0001
Loa Loa (eye worm) polyprenyl synthetase 0.003 0.0091 0.0165
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.003 0.0091 0.159
Brugia malayi orphan nuclear receptor NR2E1 0.0495 0.2556 0.4649
Echinococcus multilocularis lipoxygenase domain containing protein 0.0046 0.0174 0.0174
Schistosoma mansoni neuropeptide F-like receptor 0.0068 0.029 0.0341
Echinococcus granulosus allatostatin A receptor 0.0068 0.029 0.0341
Schistosoma mansoni hypothetical protein 0.0956 0.5009 0.5893
Echinococcus granulosus peptide allatostatin:somatostatin 0.0068 0.029 0.0341
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.004 0.0071
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0415 0.2133 0.2509
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0044 0.0164 0.0164
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0495 0.2556 0.2556
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0038 0.0088
Brugia malayi Protein K4 0.0019 0.0032 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0604 0.3137 0.7383
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.1048 0.5497 0.5497
Brugia malayi beta-lactamase family protein 0.0042 0.0152 0.0277
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0152 0.2678
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0077 0.0341 0.062
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0044 0.0166 0.035
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0049 0.0115
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0134 0.0642 0.1406
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0023
Schistosoma mansoni hypothetical protein 0.0046 0.0174 0.0204
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0277
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.004 0.0139
Schistosoma mansoni adrenodoxin 0.0026 0.0068 0.008
Loa Loa (eye worm) hypothetical protein 0.1048 0.5497 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0111 0.0262
Leishmania major cytochrome p450-like protein 0.0021 0.004 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-31 0.1048 0.5497 1
Schistosoma mansoni zinc finger protein 0.0495 0.2556 0.3007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.019
Schistosoma mansoni gliotactin 0.0013 0.0001 0.0001
Onchocerca volvulus Glucosylceramidase homolog 0.0396 0.2034 0.37
Schistosoma mansoni opsin-like receptor 0.0068 0.029 0.0341
Brugia malayi hypothetical protein 0.0495 0.2556 0.4649
Leishmania major farnesyl pyrophosphate synthase 0.012 0.0569 0.1244
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.1048 0.5497 0.6468
Echinococcus granulosus Nuclear hormone receptor HR96 0.0495 0.2556 0.3007
Mycobacterium ulcerans hypothetical protein 0.0132 0.0632 0.2261
Schistosoma mansoni hypothetical protein 0.0018 0.0027 0.0032
Loa Loa (eye worm) hypothetical protein 0.0048 0.0185 0.0337
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.1048 0.5497 0.5497
Echinococcus granulosus acetylcholinesterase 0.008 0.0352 0.0414
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0277
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0109 0.0128
Schistosoma mansoni adrenodoxin 0.0026 0.0068 0.008
Onchocerca volvulus 0.0068 0.029 0.0527
Brugia malayi nuclear receptor NHR-67 0.0495 0.2556 0.4649
Echinococcus granulosus ecdysone induced protein 78C 0.1048 0.5497 0.6468
Echinococcus multilocularis ferredoxin adrenodoxin 0.0026 0.0068 0.0068
Schistosoma mansoni hypothetical protein 0.0068 0.029 0.0341
Trichomonas vaginalis Ferredoxin 1 0.0026 0.0068 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0152 0.0358
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.004 0.0071
Loa Loa (eye worm) hypothetical protein 0.0048 0.0185 0.0337
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.003 0.0091 0.1327
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.021 0.0493
Echinococcus granulosus tachykinin peptides receptor 99D 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Echinococcus granulosus death domain containing protein 0.0017 0.0019 0.0023
Schistosoma mansoni neuropeptide f receptor 76f 0.0068 0.029 0.0341
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0144 0.0693 0.0815
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0178 0.021
Brugia malayi hypothetical protein 0.0068 0.029 0.0527
Onchocerca volvulus 0.0068 0.029 0.0527
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Onchocerca volvulus 0.0116 0.0544 0.0989
Schistosoma mansoni polycystin 1-related 0.0046 0.0174 0.0204
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0148 0.0312
Echinococcus granulosus dro:myosuppressin receptor 0.0068 0.029 0.0341
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.004 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0044 0.0164 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0023 0.0055
Echinococcus multilocularis G protein coupled receptor 139 0.0068 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0118 0.0557 0.1013
Onchocerca volvulus 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0554 0.2871 0.5222
Loa Loa (eye worm) hypothetical protein 0.0068 0.029 0.0527
Trichomonas vaginalis Ferredoxin 6 0.0026 0.0068 0.0161
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.004 0.0071
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0026 0.0068 0.0343
Onchocerca volvulus 0.0068 0.029 0.0527
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0042 0.0153 0.2238
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0026 0.0068 0.0124
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0433
Loa Loa (eye worm) TYRA-2 protein 0.0068 0.029 0.0527
Onchocerca volvulus 0.0068 0.029 0.0527
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0049 0.0089
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0023 0.0035
Loa Loa (eye worm) hypothetical protein 0.0554 0.2871 0.5222
Echinococcus granulosus g protein coupled receptor 0.0068 0.029 0.0341
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Loa Loa (eye worm) hypothetical protein 0.0495 0.2556 0.4649
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.004 0.0139
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.004 0.0197
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0068 0.029 0.029
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0185 0.0218
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0152 0.0277
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0341 0.0739
Schistosoma mansoni DNA polymerase eta 0.0022 0.0049 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0152 0.0771
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0152 0.0358
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0068 0.029 0.0527
Loa Loa (eye worm) hypothetical protein 0.0079 0.0347 0.0631
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0044 0.0166 0.2911
Giardia lamblia Farnesyl diphosphate synthase 0.012 0.0569 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0202 0.1001 0.1001
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0141 0.0166
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.003 0.0091 0.0165
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0077 0.0341 0.0401
Echinococcus granulosus orexin receptor type 2 0.0068 0.029 0.0341
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.003 0.0091 0.0185
Echinococcus multilocularis serotonin receptor 0.0068 0.029 0.029
Schistosoma mansoni amine GPCR 0.0068 0.029 0.0341
Plasmodium falciparum amino acid transporter, putative 0.0048 0.0185 0.3258
Echinococcus granulosus lipoxygenase domain containing protein 0.0046 0.0174 0.0204
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0044 0.0166 0.035
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.004 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0007 0.0013
Giardia lamblia Multidrug resistance-associated protein 1 0.0015 0.0007 0.0011
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0142 0.0684 0.1499
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0275 0.1388 0.4971
Brugia malayi Nuclear hormone receptor family member nhr-1 0.1048 0.5497 1
Mycobacterium tuberculosis Conserved protein 0.0042 0.0152 0.0771
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0142 0.0684 0.0684
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.004 0.0139
Entamoeba histolytica ABC transporter, putative 0.0015 0.0007 0.013
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0152 0.0358
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0164 0.0193
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.1048 0.5497 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0123 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.0189
Loa Loa (eye worm) hypothetical protein 0.0284 0.1436 0.2613
Plasmodium vivax ferredoxin, putative 0.0026 0.0068 0.1201
Trichomonas vaginalis Ferredoxin 4 0.0026 0.0068 0.0161
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0049 0.0058
Loa Loa (eye worm) solute carrier family 6 member 4 0.0284 0.1436 0.2613
Brugia malayi hypothetical protein 0.0046 0.0174 0.0316
Trichomonas vaginalis spcc417.12 protein, putative 0.0013 0.0001 0.0002

Activities

Activity type Activity value Assay description Source Reference
ID50 (functional) = 3.4 ug kg-1 Inhibition of the Bezold Jarisch reflex evoked by 30 ug/Kg of 5-HT. ChEMBL. 9341912
Inhibition (functional) = 86 % Antagonist activity (100 mg/Kg) for the Bezold Jarisch reflex evoked by 30(mg/Kg) of 5-HT in ethylurethane anesthetized rats (i.v.) ChEMBL. 9341912
Kb (functional) = 50.1 nM Antagonistic potency against serotonin 5-hydroxytryptamine 3 receptor in GPI assay ChEMBL. 9341912
Ki (binding) = 0.42 nM In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]-BRL-43694 from rat entorhinal cortex ChEMBL. 9341912

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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