Detailed information for compound 232243

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 459.771 | Formula: C21H23Cl3NO4-
  • H donors: 2 H acceptors: 3 LogP: 2.68 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@@H]1CCN(C[C@H]1C(=O)O)CCOC(c1ccc(cc1)Cl)c1ccc(cc1)Cl.[Cl-]
  • InChi: 1S/C21H23Cl2NO4.ClH/c22-16-5-1-14(2-6-16)20(15-3-7-17(23)8-4-15)28-12-11-24-10-9-19(25)18(13-24)21(26)27;/h1-8,18-20,25H,9-13H2,(H,26,27);1H/p-1/t18-,19+;/m0./s1
  • InChiKey: QDJMEEPWMOSSRL-GRTNUQQKSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Loa Loa (eye worm) hypothetical protein 0.0051 0.0201 0.0402
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0014 0.0028
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0021 0.0058 0.017
Giardia lamblia Threonyl-tRNA synthetase 0.0012 0.0015 0.0018
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0015 0.0029
Trypanosoma cruzi cytochrome P450, putative 0.0072 0.0302 0.2192
Echinococcus granulosus histone lysine methyltransferase setb 0.0152 0.0685 0.0685
Echinococcus granulosus Sugar transporter ERD6 protein 0.0039 0.0145 0.0145
Trypanosoma brucei sugar transporter, putative 0.0039 0.0145 0.1054
Onchocerca volvulus 0.0039 0.0145 0.023
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0025 0.0076 0.0549
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0178 0.1292
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0021 0.0058 0.0136
Trypanosoma brucei DNA polymerase IV, putative 0.0098 0.0427 0.31
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0045
Echinococcus multilocularis cpg binding protein 0.0031 0.0107 0.0107
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0116 0.0514 0.0514
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0055 0.022 0.1598
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0015 0.002
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0489 0.0977
Trichomonas vaginalis glucose transporter, putative 0.0074 0.0314 0.0443
Leishmania major DNA polymerase eta, putative 0.0022 0.0065 0.0448
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0037
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0113 0.0407
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0039 0.0145 0.0423
Schistosoma mansoni Smad4 0.0018 0.0043 0.0043
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0158 0.0715 0.1428
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0043 0.0086
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0013 0.002 0.0028
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0116 0.0513 0.1025
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0489 0.069
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.0756 0.0756
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0338 0.1574 0.5665
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Toxoplasma gondii selenide, water dikinase 0.0021 0.0058 0.021
Echinococcus granulosus muscleblind protein 0.0149 0.067 0.067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0014 0.0028
Brugia malayi hypothetical protein 0.0072 0.0304 0.0608
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0314 0.0443
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0043 0.0043
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0167 0.0756 0.1509
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0021 0.0058 0.017
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0002 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1492 0.7088 1
Brugia malayi beta-lactamase 0.0036 0.013 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0133 0.0188
Brugia malayi Cam kinase protein 1 0.0065 0.027 0.0538
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0113 0.0159
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0277 0.0391
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.013 0.0378
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0007 0.0024
Leishmania major cytochrome p450-like protein 0.0072 0.0302 0.2174
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0014 0.0028
Toxoplasma gondii facilitative glucose transporter GT1 0.0218 0.1001 0.3604
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0131 0.0261
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0058 0.0424
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0631 0.4561
Brugia malayi MH2 domain containing protein 0.026 0.1201 0.2399
Echinococcus granulosus pyruvate kinase 0.0034 0.0122 0.0122
Trypanosoma brucei chrX additional, unordered contigs 0.0022 0.0065 0.047
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0028 0.0055
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0251 0.0902
Brugia malayi 6-phosphofructokinase 0.0111 0.0489 0.0977
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0015 0.0209
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0025 0.0076 0.0076
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0021 0.0021
Onchocerca volvulus 0.0039 0.0145 0.023
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0178 0.0178
Schistosoma mansoni pyruvate kinase 0.0034 0.0122 0.0122
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0058 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1492 0.7088 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0024 0.0034
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0076 0.0151
Mycobacterium ulcerans hypothetical protein 0.0021 0.0058 0.017
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0002 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0055 0.022 0.1598
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0065 0.027 0.0538
Brugia malayi Glycosyl hydrolases family 31 protein 0.0167 0.0756 0.1509
Schistosoma mansoni sugar transporter 0.0039 0.0145 0.0145
Onchocerca volvulus 0.0027 0.0088 0.0129
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0015 0.0029
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0099 0.043 0.0606
Trichomonas vaginalis sugar transport protein, putative 0.0039 0.0145 0.0205
Plasmodium falciparum calcium-dependent protein kinase 4 0.0065 0.027 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0178 0.0251
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.013 0.0943
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.0055 0.0109
Loa Loa (eye worm) hypothetical protein 0.0051 0.02 0.04
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0102 0.0367
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0065 0.027 0.0538
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0255 0.0918
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0014 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0014 0.0028
Trichomonas vaginalis dullard protein, putative 0.0013 0.002 0.0028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0014 0.0028
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0072 0.0302 0.0878
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0015 0.0015
Toxoplasma gondii NAC domain-containing protein 0.0071 0.0298 0.1074
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0213 0.0301
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0014 0.0102
Leishmania major myo-inositol/proton symporter (MIT) 0.0039 0.0145 0.1033
Schistosoma mansoni hypothetical protein 0.0218 0.1001 0.1001
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0102 0.1275
Plasmodium vivax CDK-related protein kinase 6, putative 0.0886 0.4191 1
Leishmania major glucose transporter, lmgt3 0.0074 0.0314 0.2261
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0155 0.07 0.0987
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.1054 0.3064
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0058 0.017
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.0181 0.0651
Loa Loa (eye worm) transcription factor SMAD2 0.026 0.1201 0.2399
Echinococcus granulosus transcription factor btf3 0.0071 0.0298 0.0298
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0152 0.0685 0.0685
Plasmodium vivax hypothetical protein, conserved 0.0036 0.013 0.0276
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0065 0.027 0.0611
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0147 0.0428
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0347 0.1615 0.2278
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0063 0.026 0.0754
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0264 0.0264
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1492 0.7088 1
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0064 0.009
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0133 0.0188
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0058 0.0082
Treponema pallidum NADH oxidase 0.0055 0.022 0.0311
Giardia lamblia Fructose-bisphosphate aldolase 0.1492 0.7088 1
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0077 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0088 0.0125
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0005 0.0005
Plasmodium vivax calcium-dependent protein kinase, putative 0.0065 0.027 0.0611
Loa Loa (eye worm) hypothetical protein 0.0158 0.0715 0.1428
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0021 0.0058 0.017
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0015 0.0052
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0014 0.0028
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0032 0.0064
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0631 0.4574
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0015 0.0105
Echinococcus granulosus mitogen activated protein kinase 3 0.011 0.0484 0.0484
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0021 0.0058 0.008
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0058 0.0058
Brugia malayi Cytochrome P450 family protein 0.0063 0.026 0.0518
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0013 0.002 0.004
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0055 0.022 0.022
Entamoeba histolytica hypothetical protein 0.0047 0.0181 0.0255
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0014 0.002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Mycobacterium tuberculosis Probable dehydrogenase 0.0312 0.145 0.4215
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0014 0.0028
Mycobacterium leprae conserved hypothetical protein 0.001 0.0008 0.0023
Plasmodium falciparum glutathione reductase 0.0055 0.022 0.0522
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0102 0.0144
Plasmodium falciparum calcium-dependent protein kinase 3 0.0065 0.027 0.064
Brugia malayi beta-lactamase family protein 0.0036 0.013 0.026
Echinococcus granulosus mixed lineage leukemia protein mll 0.0013 0.002 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.013 0.0184
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0058 0.0058
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0014 0.0014
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Schistosoma mansoni disulfide oxidoreductase 0.0021 0.0058 0.0058
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0218 0.1001 0.1001
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.013 0.0378
Schistosoma mansoni hypothetical protein 0.0725 0.3421 0.3421
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.002 0.0013
Onchocerca volvulus 0.1202 0.5702 1
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0008 0.0058
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0108 0.0476 0.095
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0122 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0178 0.0251
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0014 0.0014
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0199 0.0199
Brugia malayi ImpB/MucB/SamB family protein 0.0072 0.0301 0.0602
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0085 0.0199
Echinococcus granulosus lamin 0.0027 0.0088 0.0088
Echinococcus granulosus pyruvate kinase 0.0034 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0149 0.067 0.1339
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0021 0.0058 0.0836
Schistosoma mansoni intermediate filament proteins 0.0027 0.0088 0.0088
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0014 0.0028
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0021 0.0058 0.0083
Mycobacterium tuberculosis Conserved protein 0.0036 0.013 0.0378
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0063 0.026 0.0754
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0063 0.026 0.0754
Echinococcus granulosus transient receptor potential gamma protein 0.0097 0.0421 0.0421
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0014 0.0014
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0014 0.0014
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0133 0.0946
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0102 0.024
Schistosoma mansoni hypothetical protein 0.0063 0.026 0.026
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0255 0.0741
Entamoeba histolytica hypothetical protein 0.0099 0.043 0.0606
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1492 0.7088 1
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0063 0.0089
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0039 0.0145 0.0423
Schistosoma mansoni DNA helicase recq1 0.0009 0.0002 0.0002
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0025 0.0076 0.0107
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0085 0.0617
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0014 0.0028
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0065 0.027 0.0971
Leishmania major hypothetical protein, conserved 0.0026 0.0085 0.0595
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0015 0.0209
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.0181 0.0428
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0014 0.0028
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0257 0.0257
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0024 0.0034
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0178 0.0356
Echinococcus multilocularis microtubule associated protein 2 0.2102 1 1
Schistosoma mansoni transient receptor potential channel 4 0.0097 0.0421 0.0421
Schistosoma mansoni glutamate synthase 0.0021 0.0058 0.0058
Trichomonas vaginalis rotamase, putative 0.0033 0.0117 0.0165
Schistosoma mansoni hypothetical protein 0.005 0.0198 0.0198
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0113 0.082
Schistosoma mansoni hypothetical protein 0.005 0.0198 0.0198
Schistosoma mansoni glucose transport protein 0.0218 0.1001 0.1001
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0058 0.0083
Echinococcus multilocularis pyruvate kinase 0.0067 0.0277 0.0277
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0058 0.021
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0127 0.0923
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.0181 0.0398
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0043 0.0043
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.0181 0.1291
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0271 0.0271
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0055 0.022 0.3148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0122 0.0172
Mycobacterium tuberculosis Conserved hypothetical protein 0.0157 0.0706 0.2053
Brugia malayi hypothetical protein 0.0156 0.0706 0.141
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0011
Giardia lamblia Glycyl-tRNA synthetase 0.0012 0.0015 0.0018
Mycobacterium ulcerans dehydrogenase 0.0021 0.0058 0.017
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0122 0.0439
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0158 0.1147
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Leishmania major hypothetical protein, conserved 0.0021 0.0058 0.0401
Leishmania major DNA polymerase kappa, putative 0.0078 0.0333 0.2394
Giardia lamblia Pyruvate kinase 0.0067 0.0277 0.0389
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0277 0.0553
Brugia malayi hypothetical protein 0.0017 0.004 0.008
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0003 0.0024
Trichomonas vaginalis esterase, putative 0.0036 0.013 0.0184
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0255 0.0741
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0255 0.0255
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.013 0.013
Trichomonas vaginalis dullard protein, putative 0.0013 0.002 0.0028
Trypanosoma cruzi hexose transporter, putative 0.0074 0.0314 0.2279
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0025 0.0076 0.0549
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0076 0.0895
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.022 0.1598
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0113 0.082
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0014 0.0014
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0013 0.002 0.0026
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0255 0.0741
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0055 0.022 0.1578
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0058 0.0083
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0021 0.0058 0.017
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0063 0.026 0.0754
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.0181 0.2426
Echinococcus granulosus geminin 0.0725 0.3421 0.3421
Onchocerca volvulus 0.0039 0.0145 0.023
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0024 0.0177
Echinococcus granulosus L aminoadipate semialdehyde 0.0087 0.0376 0.0376
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0055 0.022 0.1598
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0028 0.0056
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0085 0.0306
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Loa Loa (eye worm) hypothetical protein 0.0063 0.0257 0.0514
Mycobacterium ulcerans glutamate synthase subunit beta 0.0021 0.0058 0.017
Entamoeba histolytica disulphide oxidoreductase, putative 0.0021 0.0058 0.0082
Brugia malayi MAP kinase sur-1 0.011 0.0484 0.0966
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0003
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0078 0.0333 0.2394
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0427 0.31
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0055 0.022 0.0493
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0021 0.0058 0.0058
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0076 0.0076
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0063 0.026 0.0754
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0142 0.0636 0.1848
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0039 0.0145 0.2078
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0102 0.0367
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.0307 0.07
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0003 0.0024
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.0449 0.0449
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0021 0.0058 0.0058
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0065 0.047
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0076 0.0221
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.02 0.02
Leishmania major DNA polymerase kappa, putative 0.0022 0.0065 0.0448
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0063 0.0257 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.0685 0.0685
Loa Loa (eye worm) hypothetical protein 0.0049 0.0191 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0298 0.0421
Toxoplasma gondii cytochrome p450 superfamily protein 0.0063 0.026 0.0934
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0021 0.0058 0.017
Echinococcus multilocularis solute carrier family 22 0.0039 0.0145 0.0145
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0158 0.1147
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0065 0.027 0.0538
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0067 0.0277 0.0805
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Echinococcus granulosus CTD small phosphatase protein like 0.0013 0.002 0.002
Schistosoma mansoni microtubule-associated protein tau 0.2102 1 1
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0014 0.0014
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0065 0.047
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0002 0.0002
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0076 0.0147
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0072 0.0301 0.0301
Brugia malayi Thioredoxin reductase 0.0142 0.0636 0.127
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0346 0.1612 0.4685
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0449 0.3259
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0024 0.0034
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0063 0.026 0.0754
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0489 0.1422
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0076 0.0076
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0014 0.0028
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0489 0.0489
Echinococcus granulosus General substrate transporter 0.0179 0.0814 0.0814
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0088 0.0175
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0178 0.0178
Brugia malayi Pre-SET motif family protein 0.1056 0.5005 1
Mycobacterium ulcerans lipase LipD 0.0036 0.013 0.0378
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Plasmodium vivax hexose transporter 0.0218 0.1001 0.2362
Trypanosoma brucei polo-like protein kinase 0.0103 0.0449 0.3259
Trichomonas vaginalis DNA polymerase eta, putative 0.0098 0.0427 0.0603
Echinococcus multilocularis solute carrier family 22 0.0039 0.0145 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.1001 0.1413
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0021 0.0058 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0008 0.0058
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0346 0.1612 0.4685
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0014 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.0685 0.0685
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0113 0.0798
Entamoeba histolytica transcription factor BTF3, putative 0.0071 0.0298 0.0421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0122 0.0172
Loa Loa (eye worm) hypothetical protein 0.0036 0.0131 0.0261
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0427 0.31
Brugia malayi Latrophilin receptor protein 2 0.005 0.0198 0.0395
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.027 0.027
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0063 0.0257 0.0514
Giardia lamblia Kinase, CMGC MAPK 0.011 0.0484 0.068
Entamoeba histolytica protein kinase, putative 0.0065 0.027 0.038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0427 0.31
Schistosoma mansoni terminal deoxycytidyl transferase 0.0072 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0014 0.0014
Loa Loa (eye worm) histone methyltransferase 0.0015 0.0029 0.0057
Echinococcus multilocularis transient receptor potential ion channel A 0.0094 0.0405 0.0405
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0024 0.0049
Trichomonas vaginalis apoptosis inducing factor, putative 0.0021 0.0058 0.0083
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0102 0.0209
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0102 0.0209
Plasmodium falciparum pyruvate kinase 0.0067 0.0277 0.0657
Brugia malayi Sugar transporter family protein 0.0039 0.0145 0.029
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0029 0.0096 0.0346
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.013 0.0943
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0135 0.0191
Toxoplasma gondii ABC1 family protein 0.0036 0.013 0.0468
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0014 0.0028
Brugia malayi ImpB/MucB/SamB family protein 0.0072 0.0301 0.0602
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0063 0.026 0.0754
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0015 0.0015
Echinococcus granulosus dna polymerase kappa 0.0098 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0083
Echinococcus granulosus intermediate filament protein 0.0027 0.0088 0.0088
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.0756 0.0756
Trypanosoma brucei glucose transporter, putative 0.0074 0.0314 0.2279
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0277 0.0553
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0155 0.07 0.0987
Plasmodium falciparum thioredoxin reductase 0.0055 0.022 0.0522
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0085 0.017
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0152 0.0685 0.0685
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0449 0.0634
Schistosoma mansoni hypothetical protein 0.0021 0.0058 0.0058
Onchocerca volvulus 0.0039 0.0145 0.023
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0063 0.0257 0.0514
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0081 0.0162
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Echinococcus multilocularis muscleblind protein 1 0.0149 0.067 0.067
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0058 0.021
Giardia lamblia DNA repair protein RAD52 0.0347 0.1615 0.2276
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0218 0.1001 0.1001
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0029 0.0035
Schistosoma mansoni alpha glucosidase 0.0037 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0117
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0021 0.0058 0.0058
Echinococcus multilocularis geminin 0.0725 0.3421 0.3421
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0024 0.0034
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.005 0.0198 0.0198
Brugia malayi 6-phosphofructokinase 0.0111 0.0489 0.0977
Trypanosoma brucei THT1 - hexose transporter, putative 0.0074 0.0314 0.2279
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.022 0.1598
Plasmodium falciparum T-complex protein 1 subunit beta 0.0025 0.0076 0.0177
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0015 0.0029
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0271 0.0542
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0135 0.027
Toxoplasma gondii sugar transporter ST3 0.0039 0.0145 0.0523
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0178 0.0178
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0065 0.027 0.027
Echinococcus granulosus mitogen activated protein kinase 0.011 0.0484 0.0484
Treponema pallidum thioredoxin reductase (trxB) 0.0155 0.07 0.0987
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0007 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0058 0.0424
Schistosoma mansoni smad 0.0018 0.0043 0.0043
Mycobacterium ulcerans hypothetical protein 0.0036 0.013 0.0378
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0181 0.0181
Schistosoma mansoni protein kinase 0.0065 0.027 0.027
Leishmania major DNA polymerase eta, putative 0.0072 0.0301 0.2167
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0145 0.0205
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0009
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0039 0.0145 0.0423
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0181 0.0526
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0135 0.0191
Onchocerca volvulus 0.0039 0.0145 0.023
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0058 0.0058
Entamoeba histolytica protein kinase, putative 0.001 0.0007 0.001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0178 0.1292
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0058 0.0117
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0202 0.1464
Plasmodium falciparum proline--tRNA ligase 0.0073 0.0307 0.0729
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0015 0.0082
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0304 0.0304
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.027 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0077 0.0109
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0489 0.069
Toxoplasma gondii NADPH-glutathione reductase 0.0055 0.022 0.0793
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0072 0.0301 0.0602
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0087 0.0376 0.0376
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0014 0.0028
Mycobacterium tuberculosis Conserved hypothetical protein 0.001 0.0008 0.0023
Echinococcus granulosus solute carrier family 22 0.0039 0.0145 0.0145
Schistosoma mansoni protein kinase 0.0065 0.027 0.027
Echinococcus multilocularis dna polymerase eta 0.0072 0.0301 0.0301
Schistosoma mansoni hypothetical protein 0.0012 0.0015 0.0015
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0041 0.0041
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0178 0.1271
Chlamydia trachomatis pyruvate kinase 0.0067 0.0277 0.3828
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0032 0.0032
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0489 0.0977
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0116 0.0514 0.1027
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0063 0.026 0.0754
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.013 0.0943
Loa Loa (eye worm) glutathione reductase 0.0142 0.0636 0.127
Giardia lamblia NADH oxidase lateral transfer candidate 0.0055 0.022 0.0309
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0063 0.026 0.0754
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0032 0.0064
Echinococcus multilocularis musashi 0.0027 0.0088 0.0088
Schistosoma mansoni smad1 5 8 and 0.0018 0.0043 0.0043
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0147 0.0428
Brugia malayi steroid hormone receptor 0.0012 0.0014 0.0028
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.0181 0.0181
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0116 0.0514 0.0514
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0021 0.0058 0.017
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0008 0.0058
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0058 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0101 0.0143
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0055 0.022 0.3148
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0058 0.0083
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0088 0.0175
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0028
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0037
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0055 0.022 0.3002
Loa Loa (eye worm) pyruvate kinase 0.0014 0.0026 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0144
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0449 0.0634
Leishmania major basic transcription factor 3a, putative 0.0071 0.0298 0.2146
Plasmodium vivax pyruvate kinase, putative 0.0067 0.0277 0.0628
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0135 0.0191
Plasmodium falciparum basic transcription factor 3b, putative 0.0071 0.0298 0.0709
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0199 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1492 0.7088 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0036 0.013 0.026
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0055 0.022 0.0522
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0014 0.0014
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0008 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0133 0.0188
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.027 0.027
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0116 0.0513 0.3706
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0032 0.0233
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0088 0.0175
Entamoeba histolytica hypothetical protein 0.0071 0.0298 0.0421
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0218 0.1001 0.1001
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0014 0.0014
Echinococcus multilocularis pyruvate kinase 0.0034 0.0122 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0014 0.0028
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.0181 0.0255
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.0015 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0117 0.0165
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0014 0.0014
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0178 0.0356
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0063 0.026 0.0754
Schistosoma mansoni lamin 0.0027 0.0088 0.0088
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.002 0.0028
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0277 0.0462
Echinococcus multilocularis solute carrier family 22 0.0039 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0087 0.0376 0.0751
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.1378 1
Trypanosoma brucei DNA polymerase eta, putative 0.0072 0.0301 0.2185
Loa Loa (eye worm) hypothetical protein 0.0061 0.0249 0.0497
Trichomonas vaginalis rotamase, putative 0.0032 0.0113 0.016
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.0631 0.4574
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0064 0.0186
Echinococcus granulosus thioredoxin glutathione reductase 0.0142 0.0638 0.0638
Schistosoma mansoni kinase 0.0055 0.022 0.022
Schistosoma mansoni transient receptor potential channel 0.0064 0.0264 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0005 0.0007
Schistosoma mansoni glucose transport protein 0.0218 0.1001 0.1001
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0063 0.026 0.0754
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0007 0.0048
Giardia lamblia Pyruvate kinase 0.0034 0.0122 0.017
Schistosoma mansoni hypothetical protein 0.0725 0.3421 0.3421
Loa Loa (eye worm) major facilitator superfamily transporter 0.0039 0.0145 0.029
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0058 0.021
Giardia lamblia Sugar-proton symporter 0.0039 0.0145 0.0203
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0024 0.0034
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.013 0.0378
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0427 0.31
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0063 0.026 0.0754
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0116 0.0513 0.1491
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Mycobacterium ulcerans DNA polymerase IV 0.0098 0.0427 0.1242
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0065 0.047
Echinococcus granulosus solute carrier family 22 0.0039 0.0145 0.0145
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0144
Echinococcus granulosus solute carrier family 22 0.0039 0.0145 0.0145
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0489 0.3549
Brugia malayi Sugar transporter family protein 0.0218 0.1001 0.2
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0135 0.0191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0014 0.0028
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.026 0.0518
Trichomonas vaginalis glutathione reductase, putative 0.0055 0.022 0.0311
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0076 0.1085
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0058 0.0424
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0307 0.2225
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0135 0.096
Loa Loa (eye worm) cytochrome P450 0.0063 0.026 0.0518
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0155 0.07 0.0987
Brugia malayi polk-prov protein 0.0049 0.0191 0.0381
Echinococcus granulosus synaptic vesicle 2 protein 0.0039 0.0145 0.0145
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0117 0.0233
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Leishmania major pyruvate kinase 0.0067 0.0277 0.1989
Brugia malayi glutamate synthase 0.0021 0.0058 0.0117
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0007 0.0048
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.1378 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.011 0.0484 0.3508
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0014 0.0028
Entamoeba histolytica hypothetical protein 0.0025 0.0076 0.0107
Trypanosoma brucei unspecified product 0.0049 0.0195 0.1413
Schistosoma mansoni sugar transporter 0.0039 0.0145 0.0145
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1492 0.7088 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0085 0.0617
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0029 0.0029
Brugia malayi Cytochrome P450 family protein 0.0072 0.0302 0.0604
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0055 0.022 0.1578
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.0449 0.0765
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0055 0.022 0.1578
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0055 0.022 0.0522
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.013 0.0184
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Onchocerca volvulus 0.0027 0.0088 0.0129
Schistosoma mansoni lamin 0.0027 0.0088 0.0088
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0058 0.0105
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.002 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0135 0.0191
Loa Loa (eye worm) Smad1 0.0018 0.0043 0.0086
Trypanosoma brucei glucose transporter 1E 0.0074 0.0314 0.2279
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0063 0.026 0.0754
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0015 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0077 0.0109
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0058 0.0058
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0014 0.0014
Leishmania major NADH dehydrogenase, putative 0.0021 0.0058 0.0401
Leishmania major cytochrome p450-like protein 0.0063 0.026 0.1863
Echinococcus multilocularis solute carrier family 22 0.0039 0.0145 0.0145
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0063 0.026 0.1882
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0271 0.1969
Leishmania major cytochrome p450-like protein 0.0063 0.026 0.1863
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0277 0.0391
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0021 0.0058 0.0424
Schistosoma mansoni glucose transport protein 0.0218 0.1001 0.1001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1492 0.7088 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0032 0.0032
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.027 0.027
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Echinococcus granulosus GPCR family 2 0.005 0.0198 0.0198
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0008 0.0058
Treponema pallidum fructose-bisphosphate aldolase 0.1492 0.7088 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.011 0.0484 0.0484
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.057 0.2684 0.3787
Plasmodium falciparum hexose transporter 0.0218 0.1001 0.2386
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0076 0.0273
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0135 0.0135
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0014 0.0014
Trypanosoma brucei THT1 - hexose transporter, putative 0.0074 0.0314 0.2279
Mycobacterium tuberculosis Probable reductase 0.0312 0.145 0.4215
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.0449 0.0897
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0076 0.0221
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0314 0.0443
Treponema pallidum oxidoreductase 0.0021 0.0058 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0449 0.0634
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0298 0.2165
Mycobacterium ulcerans sugar transporter 0.0039 0.0145 0.0423
Trypanosoma cruzi cytochrome P450, putative 0.0072 0.0302 0.2192
Loa Loa (eye worm) hypothetical protein 0.005 0.0198 0.0395
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0271 0.1969
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0271 0.0271
Brugia malayi CXXC zinc finger family protein 0.0029 0.0099 0.0197
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0245 0.0245
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0063 0.026 0.1863
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0028
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0133 0.0967
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0049
Brugia malayi MH1 domain containing protein 0.0018 0.0043 0.0086
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0063 0.026 0.0754
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0076 0.0178
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0024 0.0034
Toxoplasma gondii thioredoxin reductase 0.0142 0.0636 0.2288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0122 0.0172
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0028
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0264 0.0264
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0058 0.0058
Mycobacterium tuberculosis Conserved protein 0.0036 0.013 0.0378
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0147 0.0428
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Plasmodium falciparum mitogen-activated protein kinase 2 0.0338 0.1574 0.3753
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0158 0.0715 0.1428
Entamoeba histolytica hypothetical protein 0.0072 0.0304 0.0429
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0015 0.0052
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0155 0.07 0.2034
Giardia lamblia DNA damage repair protein 0.0022 0.0065 0.0089
Trypanosoma cruzi DNA polymerase eta, putative 0.0072 0.0301 0.2185
Loa Loa (eye worm) hypothetical protein 0.0047 0.0181 0.0361
Schistosoma mansoni smad1 5 8 and 0.0018 0.0043 0.0043
Schistosoma mansoni cytochrome P450 0.0063 0.026 0.026
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0427 0.31
Schistosoma mansoni transient receptor potential channel 0.0097 0.0421 0.0421
Plasmodium vivax glutathione reductase, putative 0.0142 0.0636 0.1487
Loa Loa (eye worm) hypothetical protein 0.0063 0.0257 0.0514
Leishmania major trypanothione reductase 0.0142 0.0636 0.4599
Echinococcus granulosus transient receptor potential ion channel A 0.0094 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0032 0.0233
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Echinococcus granulosus glutamate synthase 0.0021 0.0058 0.0058
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0065 0.027 0.1955
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0013 0.002 0.002
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0015 0.0015
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0032 0.021
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.013 0.0378
Echinococcus multilocularis muscleblind protein 0.0149 0.067 0.067
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0312 0.145 0.4215
Onchocerca volvulus 0.0051 0.02 0.0327
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0116 0.0514 0.0514
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.0449 0.0634
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0063 0.026 0.0754
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0135 0.0191
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0063 0.026 0.0754
Brugia malayi Pyruvate kinase, M2 isozyme 0.0067 0.0277 0.0553
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0032 0.0233
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.009 0.0127
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0028
Brugia malayi Cytochrome P450 family protein 0.0072 0.0302 0.0604
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0153 0.0217
Loa Loa (eye worm) hypothetical protein 0.0009 0.0003 0.0006
Mycobacterium leprae Probable pyruvate kinase PykA 0.0067 0.0277 0.0805
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0021 0.0058 0.0058
Echinococcus multilocularis 0.0013 0.002 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0065 0.047
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Echinococcus granulosus lamin dm0 0.0027 0.0088 0.0088
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0014 0.0014
Onchocerca volvulus 0.0039 0.0145 0.023
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0489 0.069
Entamoeba histolytica thioredoxin reductase, putative 0.0155 0.07 0.0987
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0063 0.026 0.0754
Schistosoma mansoni transient receptor potential channel 0.0064 0.0264 0.0264
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0484 0.0682
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0055 0.022 0.1598
Brugia malayi Cytochrome P450 family protein 0.0063 0.026 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0298 0.0421
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0489 0.0489
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0133 0.0188
Plasmodium falciparum DNA repair protein REV1, putative 0.0022 0.0065 0.0151
Loa Loa (eye worm) T-complex protein 1 0.0025 0.0076 0.0151
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.002 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0427 0.31
Entamoeba histolytica deoxycytidyl transferase, putative 0.0072 0.0301 0.0425
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.0449 0.3243
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0427 0.31
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0155 0.07 0.2034
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0218 0.1001 0.1001
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0063 0.026 0.1882
Echinococcus multilocularis thioredoxin glutathione reductase 0.0142 0.0638 0.0638
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0199 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0063 0.026 0.1882
Schistosoma mansoni glutamate synthase 0.0021 0.0058 0.0058
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0034 0.012 0.024
Trypanosoma brucei DNA polymerase IV, putative 0.0098 0.0427 0.31
Plasmodium falciparum ferrodoxin reductase-like protein 0.0021 0.0058 0.0136
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0489 0.069
Onchocerca volvulus 0.0036 0.013 0.0203
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0063 0.026 0.0754
Brugia malayi nuclear receptor NHR-88 0.0012 0.0014 0.0028
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0489 0.0489
Echinococcus granulosus lysosomal alpha glucosidase 0.0167 0.0756 0.0756
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0014 0.0014
Schistosoma mansoni DNA polymerase IV / kappa 0.0022 0.0065 0.0065
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trypanosoma brucei unspecified product 0.0092 0.0396 0.2873
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.0181 0.1311
Chlamydia trachomatis thioredoxin reductase 0.0155 0.07 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0022 0.0065 0.047
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0226 0.164
Toxoplasma gondii sugar transporter ST1 0.0039 0.0145 0.0523
Toxoplasma gondii t-complex protein beta subunit 0.0025 0.0076 0.0272
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.0307 0.1104
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0181 0.0181
Plasmodium falciparum glutathione reductase 0.0142 0.0636 0.1514
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0085 0.0617
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0025 0.0076 0.0146
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0013 0.002 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0427 0.31
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0025 0.0076 0.0107
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0015 0.0015
Trichomonas vaginalis myo-inositol transporter, putative 0.0039 0.0145 0.0205
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0489 0.0489
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0076 0.0151
Echinococcus multilocularis dna polymerase kappa 0.0098 0.0427 0.0427
Echinococcus multilocularis expressed protein 0.0033 0.0117 0.0117
Brugia malayi Muscleblind-like protein 0.0149 0.067 0.1339
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0314 0.0443
Trypanosoma cruzi hexose transporter, putative 0.0039 0.0145 0.1054
Brugia malayi pyruvate kinase 0.0014 0.0026 0.0051
Loa Loa (eye worm) hypothetical protein 0.0065 0.027 0.0538
Onchocerca volvulus 0.0021 0.0058 0.0078
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0021 0.0058 0.017
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0015 0.0042
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0058 0.0058
Loa Loa (eye worm) ICD-1 protein 0.0071 0.0298 0.0596
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0484 0.0484
Onchocerca volvulus 0.0036 0.013 0.0203
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0218 0.1001 0.1001
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0024 0.0034
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0135 0.027
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0729 0.3441 1
Loa Loa (eye worm) POT family protein 0.0082 0.0349 0.0697
Loa Loa (eye worm) CYP4Cod1 0.0072 0.0302 0.0604
Trypanosoma brucei transcription factor BTF3, putative 0.0071 0.0298 0.2165
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0218 0.1001 0.1001
Loa Loa (eye worm) sugar transporter 0.0039 0.0145 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0298 0.0421
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0039 0.0145 0.0343
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0255 0.0255
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0489 0.1422
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0063 0.0257 0.0257
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0116 0.0513 0.1491
Brugia malayi hypothetical protein 0.0026 0.0085 0.017
Echinococcus multilocularis 0.0063 0.026 0.026
Leishmania major DNA damage repair protein, putative 0.0022 0.0065 0.0448
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0063 0.0125
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0022 0.0065 0.0233
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0017 0.0025
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.001 0.0008 0.0029
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0264 0.0264
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0055 0.022 0.022
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0063 0.026 0.0754
Loa Loa (eye worm) thioredoxin reductase 0.0142 0.0636 0.127
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0058 0.0082
Brugia malayi Sugar transporter family protein 0.0039 0.0145 0.029
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0255 0.183
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0135 0.0982
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.013 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0014 0.0028
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0122 0.0172
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1492 0.7088 1
Loa Loa (eye worm) programmed cell death 8 0.0021 0.0058 0.0117
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.013 0.013
Echinococcus multilocularis transient receptor potential gamma protein 0.0097 0.0421 0.0421
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0063 0.026 0.0754
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0063 0.026 0.1882
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0015 0.002
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.001 0.0007 0.0096
Brugia malayi Pyruvate kinase, muscle isozyme 0.0067 0.0277 0.0553
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.027 0.027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0014 0.0028
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0014 0.0014
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0055 0.022 0.064
Loa Loa (eye worm) hypothetical protein 0.0036 0.013 0.026
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0014 0.0014
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0043 0.0043
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0039 0.0145 0.0145
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0032 0.021
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0058 0.0424
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0307 0.2207
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0115 0.023
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0063 0.0089
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0198 0.0198
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0015 0.0029
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0729 0.3441 1
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0008 0.0058
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0489 0.069
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0264 0.0264
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0152 0.0685 0.0685
Trypanosoma brucei glucose transporter, putative 0.0074 0.0314 0.2279
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0021 0.0058 0.017
Echinococcus granulosus pyruvate kinase 0.0067 0.0277 0.0277
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0063 0.026 0.0754
Plasmodium vivax basic transcription factor 3b, putative 0.0071 0.0298 0.068
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.027 0.027
Schistosoma mansoni hypothetical protein 0.0072 0.0304 0.0304
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0034 0.012 0.024
Schistosoma mansoni DNA helicase recq5 0.0009 0.0002 0.0002
Plasmodium falciparum calcium-dependent protein kinase 2 0.0065 0.027 0.064
Loa Loa (eye worm) pyruvate kinase-PB 0.0046 0.0181 0.0361
Giardia lamblia TCP-1 chaperonin subunit beta 0.0025 0.0076 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0449 0.0634
Schistosoma mansoni glutamate synthase 0.0021 0.0058 0.0058
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.013 0.013
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0085 0.0199
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0257 0.0257
Plasmodium falciparum thioredoxin reductase 0.0142 0.0636 0.1514
Brugia malayi MH1 domain containing protein 0.0018 0.0043 0.0086
Echinococcus granulosus Smad4 0.0018 0.0043 0.0043
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0076 0.055
Echinococcus multilocularis Smad4 0.0018 0.0043 0.0043
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0116 0.0513 0.0513
Toxoplasma gondii pyruvate kinase PyK1 0.0067 0.0277 0.0996
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0028
Loa Loa (eye worm) hypothetical protein 0.0108 0.0476 0.095
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0015 0.0042
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0013 0.002 0.0044
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0014 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0063 0.026 0.0754
Brugia malayi MH2 domain containing protein 0.0018 0.0043 0.0086
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.013 0.0378
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0449 0.0634
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0198 0.0395
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0032 0.0233
Trypanosoma brucei glucosidase, putative 0.0037 0.0135 0.0982
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0015 0.0105
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0304 0.0304
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0021 0.0058 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0008 0.0011
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0063 0.0257 0.0363
Schistosoma mansoni sugar transporter 0.0039 0.0145 0.0145
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0058 0.0424
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.027 0.038
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0013 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Leishmania major pyruvate kinase 0.0067 0.0277 0.1989
Plasmodium vivax DNA repair protein REV1, putative 0.0022 0.0065 0.0121
Onchocerca volvulus 0.0096 0.042 0.0712
Plasmodium falciparum protein kinase 7 0.059 0.2778 0.6627
Entamoeba histolytica SH2-protein kinase domain containing protein 0.001 0.0007 0.001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0255 0.0741
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0116 0.0513 0.0513
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0191 0.1385
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.0181 0.0181
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0063 0.026 0.0754
Leishmania major hypothetical protein, conserved 0.001 0.0008 0.0034
Trypanosoma cruzi hexose transporter, putative 0.0074 0.0314 0.2279
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.0181 0.0526
Leishmania major glucose transporter, lmgt2 0.0074 0.0314 0.2261
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0028 0.0055
Echinococcus granulosus expressed protein 0.0033 0.0117 0.0117
Toxoplasma gondii transporter, major facilitator family protein 0.0039 0.0145 0.0523
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0063 0.026 0.0754
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0063 0.026 0.0754
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0226 0.164
Onchocerca volvulus 0.0039 0.0145 0.023
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.005 0.036
Trypanosoma brucei glucose transporter, putative 0.0074 0.0314 0.2279
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0021 0.0058 0.017
Loa Loa (eye worm) cytochrome P450 family protein 0.0072 0.0302 0.0604
Echinococcus multilocularis transcription factor btf3 0.0071 0.0298 0.0298
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.022 0.1598
Plasmodium vivax ferrodoxin reductase, putative 0.0021 0.0058 0.0105
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0155 0.07 0.0987
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0014 0.0028
Trichomonas vaginalis set domain proteins, putative 0.1202 0.5702 0.8045
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0312 0.145 0.4215
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0021 0.0058 0.0117
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1056 0.5005 1
Plasmodium vivax SET domain protein, putative 0.0152 0.0685 0.1605
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0087 0.0376 0.0751
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0065 0.027 0.0611
Leishmania major hypothetical protein, conserved 0.0039 0.0145 0.1033
Trypanosoma brucei glucose transporter, putative 0.0074 0.0314 0.2279
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0489 0.069
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0298 0.2165
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0449 0.0634
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0028
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0135 0.0191
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0029
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0158 0.1147
Loa Loa (eye worm) hypothetical protein 0.0046 0.0181 0.0361
Loa Loa (eye worm) sugar transporter 0.0218 0.1001 0.2
Treponema pallidum threonyl-tRNA synthetase 0.0012 0.0015 0.0021
Schistosoma mansoni protein kinase 0.0065 0.027 0.027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0283 0.0283
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0312 0.145 0.4215
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0024 0.0153
Brugia malayi pyruvate kinase, muscle isozyme 0.0014 0.0026 0.0051
Giardia lamblia DINP protein human, muc B family 0.0078 0.0333 0.0467
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0024 0.0034
Onchocerca volvulus 0.0039 0.0145 0.023
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0117 0.0233
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0063 0.026 0.0754
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0135 0.0982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.009 0.0127
Trypanosoma brucei pyruvate kinase 1, putative 0.0067 0.0277 0.2008
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0277 0.2008
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0043 0.0043
Plasmodium vivax sugar transporter, putative 0.0039 0.0145 0.0313
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0063 0.0257 0.0363
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.0449 0.0449
Giardia lamblia Prolyl-tRNA synthetase 0.0063 0.0257 0.0361
Entamoeba histolytica dual specificity protein phosphatase, putative 0.057 0.2684 0.3787
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0338 0.1574 0.3733
Schistosoma mansoni DNA polymerase eta 0.0072 0.0301 0.0301
Echinococcus multilocularis synaptic vesicle 2 protein 0.0039 0.0145 0.0145
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0152 0.0685 0.0685
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0022 0.0065 0.0233
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0146 0.0655 0.0655
Brugia malayi beta-NAC-like protein 0.0071 0.0298 0.0596
Loa Loa (eye worm) cytochrome P450 family protein 0.0072 0.0302 0.0604
Leishmania major glucose transporter/membrane transporter D2, putative 0.0074 0.0314 0.2261
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0058 0.017
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Echinococcus granulosus pyruvate kinase 0.0034 0.0122 0.0122
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0015 0.0015
Schistosoma mansoni pyruvate kinase 0.0067 0.0277 0.0277
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0122 0.0438
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0055 0.022 0.064
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0135 0.0191
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0058 0.0424
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0144
Echinococcus multilocularis pyruvate kinase 0.0053 0.021 0.021
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0484 0.0682
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0449 0.0634
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0135 0.0191
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0063 0.026 0.0754
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0158 0.1147
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.013 0.0378
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0055 0.022 0.1598
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0015 0.0105
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0178 0.1292
Trypanosoma brucei cytochrome P450, putative 0.0072 0.0302 0.2192
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1492 0.7088 1
Giardia lamblia Kinase, PLK 0.0103 0.0449 0.0632
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0133 0.0967
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0076 0.0107
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0102 0.024
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0065 0.047
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0028
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.002 0.0013
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0102 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0449 0.0449
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0135 0.0191
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.013 0.026
Onchocerca volvulus 0.0039 0.0145 0.023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0014 0.0028
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0076 0.0221
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0116 0.0513 0.1491
Trypanosoma brucei pyruvate kinase 1 0.0067 0.0277 0.2008
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Schistosoma mansoni pyruvate kinase 0.0067 0.0277 0.0277
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0015 0.0042
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0729 0.3441 1
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.002 0.002
Mycobacterium ulcerans DNA polymerase IV 0.0098 0.0427 0.1242
Onchocerca volvulus 0.0036 0.013 0.0203
Trypanosoma brucei glucose transporter, putative 0.0074 0.0314 0.2279
Mycobacterium ulcerans NADH dehydrogenase 0.0021 0.0058 0.017
Onchocerca volvulus 0.0039 0.0145 0.023
Echinococcus multilocularis lamin dm0 0.0027 0.0088 0.0088
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.022 0.1598
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.002 0.0028
Schistosoma mansoni rotamase 0.0033 0.0117 0.0117
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0312 0.145 0.4215
Mycobacterium leprae conserved hypothetical protein 0.0036 0.013 0.0378
Loa Loa (eye worm) nuclear factor I 0.001 0.0005 0.0011
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0021 0.0021
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0218 0.1001 0.1001
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.011 0.0484 0.3508
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0076 0.0528
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0055 0.022 0.044
Echinococcus multilocularis tumor protein p63 0.0346 0.161 0.161
Brugia malayi Pre-SET motif family protein 0.0152 0.0685 0.1368
Echinococcus granulosus pyruvate kinase 0.0067 0.0277 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0427 0.31
Trypanosoma brucei glucose transporter, putative 0.0074 0.0314 0.2279
Onchocerca volvulus Putative transporter 0.0039 0.0145 0.023
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0058 0.0424
Trypanosoma cruzi hexose transporter 0.0074 0.0314 0.2279
Loa Loa (eye worm) hypothetical protein 0.0149 0.067 0.1339
Brugia malayi hypothetical protein 0.0039 0.0145 0.029
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0055 0.022 0.0493
Loa Loa (eye worm) beta-lactamase 0.0036 0.013 0.026
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0055 0.022 0.022
Onchocerca volvulus 0.0156 0.0706 0.1216
Brugia malayi Calcitonin receptor-like protein seb-1 0.0158 0.0715 0.1428
Loa Loa (eye worm) RecQ helicase 0.0022 0.0063 0.0125
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0021 0.0058 0.017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1492 0.7088 1
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0131 0.0131
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0063 0.026 0.0754
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0021 0.0058 0.0401
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0085 0.0169
Brugia malayi Major Facilitator Superfamily protein 0.0039 0.0145 0.029
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0014 0.0014
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0116 0.0513 0.0513
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0307 0.2225
Onchocerca volvulus 0.0039 0.0145 0.023
Echinococcus multilocularis glutamate synthase 0.0021 0.0058 0.0058
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0024 0.0034
Brugia malayi ecdysteroid receptor 0.0012 0.0014 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0014 0.0028
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0058 0.0083
Schistosoma mansoni hypothetical protein 0.0013 0.0019 0.0019
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0029 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0489 0.069
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0255 0.0255
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0063 0.026 0.0754
Brugia malayi phosphofructokinase 0.0111 0.0489 0.0977
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.027 0.027
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0072 0.0301 0.0301
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0098 0.0427 0.0603
Plasmodium falciparum calcium-dependent protein kinase 5 0.0065 0.027 0.064
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0489 0.1422
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0063 0.026 0.0754
Schistosoma mansoni cpg binding protein 0.0031 0.0107 0.0107
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.011 0.0484 0.3493
Brugia malayi nuclear hormone receptor 0.0012 0.0014 0.0028
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0065 0.027 0.0611
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0099 0.0197
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0021 0.0058 0.021
Trypanosoma brucei glucose transporter 2A 0.0074 0.0314 0.2279
Schistosoma mansoni coup transcription factor 0.0012 0.0014 0.0014
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0021 0.0058 0.017
Trichomonas vaginalis mercuric reductase, putative 0.0055 0.022 0.0311
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0014 0.0014
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0063 0.026 0.0754
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Leishmania major hypothetical protein, conserved 0.0021 0.0058 0.0401
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0297 0.1378 1
Schistosoma mansoni smad1 5 8 and 0.0018 0.0043 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0036 0.013 0.026
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0013 0.002 0.0071
Echinococcus granulosus bloom syndrome protein 0.0022 0.0063 0.0063
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0055 0.022 0.0793
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0015 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0314 0.0443
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0063 0.0257 0.0748
Trypanosoma brucei glucose transporter, putative 0.0074 0.0314 0.2279
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0135 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0427 0.31
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0146 0.0206
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0014 0.0028
Plasmodium falciparum calcium-dependent protein kinase 1 0.0065 0.027 0.064
Leishmania major hypothetical protein, conserved 0.0021 0.0058 0.0401
Echinococcus granulosus tumor protein p63 0.0346 0.161 0.161
Schistosoma mansoni alpha-glucosidase 0.0144 0.0645 0.0645
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.0333 0.2412
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0178 0.1271
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0277 0.0462
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0008 0.0011
Leishmania major mitochondrial DNA polymerase beta 0.0297 0.1378 1
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0039 0.0145 0.0423
Toxoplasma gondii non-specific serine/threonine protein kinase 0.001 0.0005 0.0017
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0058 0.0083
Brugia malayi Major Facilitator Superfamily protein 0.0039 0.0145 0.029
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0014 0.0102
Onchocerca volvulus 0.0039 0.0145 0.023
Toxoplasma gondii sugar transporter ST2 0.0039 0.0145 0.0523
Schistosoma mansoni cpg binding protein 0.0031 0.0107 0.0107
Trypanosoma brucei unspecified product 0.0049 0.0195 0.1413
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0043 0.0043
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0116 0.0514 0.0514
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.027 0.027
Schistosoma mansoni alpha-glucosidase 0.0144 0.0645 0.0645
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Entamoeba histolytica hypothetical protein 0.0072 0.0304 0.0429
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0122 0.0257
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.013 0.026
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0058 0.0424
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0021 0.0058 0.0117
Giardia lamblia Thioredoxin reductase 0.0155 0.07 0.0985
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0145 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0122 0.0172
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0277 0.0553
Mycobacterium ulcerans pyruvate kinase 0.0067 0.0277 0.0805
Echinococcus granulosus smad 0.0018 0.0043 0.0043
Schistosoma mansoni transcription factor btf3 0.0071 0.0298 0.0298
Echinococcus multilocularis pyruvate kinase 0.0067 0.0277 0.0277
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.0181 0.0253
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0144
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0058 0.0424
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0427 0.31
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0102 0.0144
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0014 0.0014
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0102 0.0142
Schistosoma mansoni hypothetical protein 0.0108 0.0476 0.0476
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0055 0.022 0.064
Entamoeba histolytica hypothetical protein 0.0072 0.0304 0.0429
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0213 0.0301
Leishmania major protein kinase, putative 0.0065 0.027 0.1936
Onchocerca volvulus 0.0152 0.0685 0.1179
Trypanosoma brucei NADH dehydrogenase 0.0021 0.0058 0.0424
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.011 0.0484 0.3508
Brugia malayi Smad1 0.0018 0.0043 0.0086
Brugia malayi cytochrome P450 0.0063 0.026 0.0518
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0013 0.002 0.002
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0489 0.3549
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0145 0.0205
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0489 0.3534
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0145 0.0205
Toxoplasma gondii protein kinase, putative 0.059 0.2778 1
Echinococcus multilocularis pyruvate kinase 0.0034 0.0122 0.0122
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0055 0.022 0.1578
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0307 0.2207
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0199 0.0398
Echinococcus granulosus solute carrier family 22 0.0039 0.0145 0.0145
Echinococcus granulosus transcription factor Dp 1 0.0038 0.014 0.014
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0346 0.1612 0.4685
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0076 0.0273
Onchocerca volvulus 0.0039 0.0145 0.023
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0021 0.0058 0.017
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0307 0.2225
Loa Loa (eye worm) hypothetical protein 0.0072 0.0301 0.0602
Loa Loa (eye worm) hypothetical protein 0.0097 0.0421 0.0841
Brugia malayi latrophilin 2 splice variant baaae 0.0108 0.0476 0.095
Trichomonas vaginalis dullard protein, putative 0.0013 0.002 0.0028
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0198 0.0198
Brugia malayi beta-lactamase family protein 0.0036 0.013 0.026
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.005 0.0116
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0014 0.0014
Mycobacterium leprae Probable lipase LipE 0.0036 0.013 0.0378
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0199 0.0199
Echinococcus multilocularis mitogen activated protein kinase 0.011 0.0484 0.0484
Schistosoma mansoni cpg binding protein 0.0029 0.0099 0.0099
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0152 0.0685 0.2466
Echinococcus granulosus Solute carrier family 22 5 0.1036 0.4909 0.4909
Loa Loa (eye worm) hypothetical protein 0.0027 0.0088 0.0175
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0199 0.0398
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0021 0.0058 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0427 0.31
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0122 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0077 0.0109
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0021 0.0058 0.0082
Echinococcus granulosus cpg binding protein 0.0031 0.0107 0.0107
Trypanosoma brucei glucose transporter, putative 0.0074 0.0314 0.2279
Onchocerca volvulus 0.0039 0.0145 0.023
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0032 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0063 0.026 0.0754
Mycobacterium ulcerans beta-lactamase 0.0036 0.013 0.0378
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0028 0.0101
Echinococcus multilocularis smad 0.0018 0.0043 0.0043
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0063 0.026 0.0754
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0271 0.0383
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0043 0.0086
Brugia malayi MH1 domain containing protein 0.001 0.0005 0.0011
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0063 0.0063
Onchocerca volvulus 0.0039 0.0145 0.023
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0039 0.0145 0.0145
Trichomonas vaginalis glucose transporter, putative 0.0074 0.0314 0.0443
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0271 0.0271
Entamoeba histolytica hypothetical protein 0.0072 0.0304 0.0429
Brugia malayi glutathione reductase 0.0142 0.0636 0.127
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0076 0.0221
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0271 0.195
Schistosoma mansoni hypothetical protein 0.005 0.0198 0.0198
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0135 0.0135
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0058 0.0083
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0144
Trypanosoma brucei DNA polymerase IV, putative 0.0092 0.0396 0.2873
Giardia lamblia Hexose transporter 0.0039 0.0145 0.0203
Giardia lamblia GTOR 0.0046 0.0178 0.0249
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.0449 0.0897
Onchocerca volvulus 0.0087 0.0376 0.0636
Loa Loa (eye worm) hypothetical protein 0.0036 0.013 0.026
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0014 0.0079
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0014 0.0014
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0102 0.1275
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0116 0.0514 0.0514
Brugia malayi intermediate filament protein 0.0027 0.0088 0.0175
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0015 0.0021
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0312 0.145 0.4215
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0063 0.026 0.0754
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0077 0.0109
Giardia lamblia Glutamate synthase 0.0021 0.0058 0.008
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.013 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.009 0.0127
Loa Loa (eye worm) major facilitator superfamily transporter 0.0039 0.0145 0.029
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0078 0.0333 0.0966
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0007 0.0048
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0025 0.0076 0.0076
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.013 0.013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0014 0.0014
Echinococcus multilocularis General substrate transporter 0.0179 0.0814 0.0814
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0178 0.1292
Brugia malayi major facilitator superfamily protein 0.0039 0.0145 0.029
Brugia malayi hypothetical protein 0.0039 0.0145 0.029
Trypanosoma cruzi trypanothione reductase, putative 0.0142 0.0636 0.4612
Loa Loa (eye worm) hypothetical protein 0.0026 0.0085 0.017
Schistosoma mansoni sugar transporter 0.0039 0.0145 0.0145
Entamoeba histolytica protein kinase, putative 0.0065 0.027 0.038
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.002 0.0144
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0255 0.0255
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0024 0.0177
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.013 0.0378
Plasmodium vivax thioredoxin reductase, putative 0.0142 0.0636 0.1487
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.0181 0.1311
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0015 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trichomonas vaginalis chaperonin, putative 0.0025 0.0076 0.0107
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0152 0.0685 0.1368
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0058 0.0401
Loa Loa (eye worm) MH2 domain-containing protein 0.026 0.1201 0.2399
Brugia malayi major facilitator superfamily protein 0.0039 0.0145 0.029
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0245 0.0245
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0489 0.069
Trypanosoma cruzi hexose transporter, putative 0.0074 0.0314 0.2279
Echinococcus multilocularis GPCR, family 2 0.005 0.0198 0.0198
Mycobacterium tuberculosis Conserved hypothetical protein 0.0072 0.0301 0.0876
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0003
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0039 0.0145 0.1054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0088 0.0125
Loa Loa (eye worm) hypothetical protein 0.0156 0.0706 0.141
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0065 0.027 0.0971
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0484 0.3508
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0024 0.0177
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0484 0.0682
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0191 0.1385
Trypanosoma cruzi sugar transporter, putative 0.0039 0.0145 0.1054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0077 0.0109
Brugia malayi Major Facilitator Superfamily protein 0.0039 0.0145 0.029
Loa Loa (eye worm) hypothetical protein 0.0036 0.013 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0065 0.047
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0218 0.1001 0.1001
Brugia malayi MH1 domain containing protein 0.001 0.0005 0.0011
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.002 0.0028
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0021 0.0058 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0063 0.026 0.0754
Echinococcus granulosus dna polymerase eta 0.0072 0.0301 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0045
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0122 0.0287
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0155 0.07 0.2034
Mycobacterium ulcerans monoxygenase 0.0021 0.0058 0.017
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.011 0.0484 0.0966
Schistosoma mansoni glucose transporter 0.0039 0.0145 0.0145
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0021 0.0058 0.0058
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.014 0.014
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0072 0.0301 0.0301
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0063 0.026 0.0754
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0116 0.0514 0.1027
Loa Loa (eye worm) hypothetical protein 0.0013 0.002 0.004
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0063 0.026 0.0754
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0058 0.0424
Toxoplasma gondii hypothetical protein 0.0048 0.0188 0.0675
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0145 0.0205
Trypanosoma brucei THT1 - hexose transporter, putative 0.0074 0.0314 0.2279
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0002 0.0005
Brugia malayi POT family protein 0.0082 0.0349 0.0697
Mycobacterium tuberculosis Probable oxidoreductase 0.0346 0.1612 0.4685
Onchocerca volvulus 0.0029 0.0099 0.0148
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0024 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0058 0.0424
Mycobacterium ulcerans hypothetical protein 0.001 0.0008 0.0023
Leishmania major hypothetical protein, conserved 0.001 0.0008 0.0034
Loa Loa (eye worm) hypothetical protein 0.0036 0.013 0.026
Mycobacterium ulcerans hypothetical protein 0.0157 0.0706 0.2053
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0155 0.07 1
Mycobacterium leprae putative cytochrome p450 0.0063 0.026 0.0754
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.022 0.1598
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0063 0.026 0.0754
Leishmania major T-complex protein 1, beta subunit, putative 0.0025 0.0076 0.0527
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.022 0.1598
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0077 0.0109
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0314 0.0443
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0021 0.0058 0.0836
Echinococcus multilocularis L aminoadipate semialdehyde 0.0087 0.0376 0.0376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0133 0.0188
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0178 0.0251
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0055 0.022 0.064
Leishmania major hypothetical protein, conserved 0.0036 0.013 0.0922
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0058 0.0136
Onchocerca volvulus 0.0039 0.0145 0.023
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.013 0.0378
Leishmania major glucose transporter, lmgt1 0.0074 0.0314 0.2261
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0131 0.0131
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0181 0.0526
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.011 0.0484 0.1741
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0304 0.0304
Trypanosoma brucei DNA damage repair protein, putative 0.0022 0.0065 0.047
Brugia malayi MH2 domain containing protein 0.0018 0.0043 0.0086
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0198 0.0198
Mycobacterium ulcerans ferredoxin reductase 0.0021 0.0058 0.017
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0063 0.026 0.0754
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0199 0.0199
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0484 0.0682
Entamoeba histolytica pyruvate kinase, putative 0.0046 0.0181 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0145 0.0205
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0155 0.07 0.0987
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0063 0.026 0.0754
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0065 0.047
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0449 0.3259
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0199 0.0199
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.022 0.1598
Brugia malayi lysyl-tRNA synthetase 0.0047 0.0181 0.0361
Mycobacterium tuberculosis Conserved protein 0.0036 0.013 0.0378
Echinococcus granulosus tyrosine protein kinase Lyn 0.001 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0106 0.0149
Trypanosoma brucei trypanothione reductase 0.0142 0.0636 0.4612
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0226 0.164
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0484 0.3508
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0277 0.0462
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0113 0.082
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0021 0.0058 0.0058
Leishmania major hypothetical protein, conserved 0.0013 0.002 0.0121
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0065 0.027 0.0971
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0003
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0937 0.4436 0.4436
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0277 0.2008
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0198 0.0395
Echinococcus multilocularis lamin 0.0027 0.0088 0.0088
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.013 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0014 0.0028
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0489 0.0977
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0028
Trypanosoma brucei protein kinase, putative 0.011 0.0484 0.3508
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0021 0.0058 0.0424
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0178 0.0251
Loa Loa (eye worm) hypothetical protein 0.0067 0.0277 0.0553
Brugia malayi hypothetical protein 0.0039 0.0145 0.029
Mycobacterium ulcerans integral membrane transport protein 0.0039 0.0145 0.0423
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0178 0.0251
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0062 0.0452
Plasmodium falciparum protein kinase 6 0.0886 0.4191 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0271 0.0542
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.011 0.0484 0.3493
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0198 0.0198
Trypanosoma cruzi glucose transporter, putative 0.0039 0.0145 0.1054
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0021 0.0058 0.021
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0021 0.0058 0.0105
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0015 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0098 0.0427 0.31
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0271 0.1969
Loa Loa (eye worm) hypothetical protein 0.0039 0.0145 0.029
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.013 0.0378
Echinococcus multilocularis pyruvate kinase 0.0034 0.0122 0.0122
Mycobacterium leprae Conserved hypothetical protein 0.0063 0.026 0.0754
Echinococcus granulosus cytochrome P450 2K1 0.0063 0.026 0.026
Mycobacterium ulcerans hypothetical protein 0.0022 0.0065 0.0189
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0102 0.0367
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0064 0.0722
Trichomonas vaginalis glucose transporter, putative 0.0039 0.0145 0.0205
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0135 0.0487
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0055 0.022 0.1598
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0014 0.002

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 1.5 uM In vitro inhibition of [3H]-GABA uptake in rat Hippocampal slices. ChEMBL. 1433224

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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