Detailed information for compound 334881

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 267.367 | Formula: C14H25N3O2
  • H donors: 1 H acceptors: 2 LogP: 4.78 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@H](OC(=O)NN(C(C)C)C#N)CC1CCCCC1
  • InChi: 1S/C14H25N3O2/c1-11(2)17(10-15)16-14(18)19-12(3)9-13-7-5-4-6-8-13/h11-13H,4-9H2,1-3H3,(H,16,18)/t12-/m0/s1
  • InChiKey: YCYQOGPWUSMXGX-LBPRGKRZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cathepsin H Starlite/ChEMBL References
Homo sapiens cathepsin K Starlite/ChEMBL References
Homo sapiens cathepsin B Starlite/ChEMBL References
Homo sapiens cathepsin L Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Brugia malayi cathepsin B-like cysteine proteinase Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127800 All targets in OG5_127800
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni SmCB2 peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase C (CPC), putative Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cathepsin B Get druggable targets OG5_127800 All targets in OG5_127800
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase C (CPC), putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania infantum cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase C (CPC), putative,CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like, putative Get druggable targets OG5_127800 All targets in OG5_127800
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin B Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin B-like protease (Precursor), related Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01363 cathepsin B [EC3.4.22.1], putative Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum dipeptidyl aminopeptidase 1 cathepsin B 339 aa 368 aa 26.9 %
Plasmodium falciparum cysteine proteinase falcipain 2b cathepsin H 335 aa 340 aa 33.2 %
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin K 329 aa 349 aa 33.2 %
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin L 333 aa 359 aa 30.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0038 0.004 0.0221
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0161 0.0305
Brugia malayi Cathepsin L-like cysteine proteinase 0.0046 0.0069 0.0096
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0061 0.0122 0.0227
Echinococcus multilocularis cyclin dependent kinase 0.0072 0.0158 0.0154
Schistosoma mansoni tyrosine kinase 0.0041 0.0052 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0097 0.0246 0.0464
Echinococcus granulosus neuropeptide receptor A26 0.0462 0.1512 0.1509
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1239 0.421 0.7943
Onchocerca volvulus 0.0041 0.0052 0.0137
Loa Loa (eye worm) hypothetical protein 0.0036 0.0034 0.0036
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0195 0.0587 0.0657
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.1012 0.342 0.3417
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0526 0.0993
Echinococcus multilocularis insulin receptor 0.0181 0.0537 0.0533
Trichomonas vaginalis AGC family protein kinase 0.0426 0.1389 0.262
Toxoplasma gondii AGC kinase 0.0032 0.0019 0.0128
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0176 0.0518 0.0514
Schistosoma mansoni hypothetical protein 0.0107 0.0282 0.028
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0019 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0079 0.0077
Onchocerca volvulus Cathepsin F homolog 0.0073 0.0161 0.0466
Loa Loa (eye worm) plexin A 0.0053 0.0093 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0128 0.0352 0.0665
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.1072 0.3629 0.6847
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0058 0.0112 0.0157
Echinococcus multilocularis serine:threonine protein kinase 0.0048 0.0075 0.0071
Trichomonas vaginalis STE family protein kinase 0.0057 0.0105 0.0199
Brugia malayi CXXC zinc finger family protein 0.0028 0.0007 0.0007
Brugia malayi RNA recognition motif domain containing protein 0.0191 0.0572 0.0816
Echinococcus granulosus tyrosine protein kinase csk 0.0038 0.0041 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.07 0.1321
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0031 0.0016 0.0011
Echinococcus granulosus cathepsin b 0.0181 0.0536 0.0532
Echinococcus multilocularis death associated protein kinase 1 0.0338 0.1084 0.108
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Echinococcus granulosus casein kinase I delta 0.0031 0.0016 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.004 0.0075
Trypanosoma cruzi aurora B kinase, putative 0.0081 0.0188 0.0353
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0061 0.0122 0.0227
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0031 0.0015 0.0026
Schistosoma mansoni tyrosine kinase 0.0141 0.0399 0.0397
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0241 0.0745 0.8108
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.0647 0.0646
Onchocerca volvulus 0.032 0.1019 0.3051
Loa Loa (eye worm) RNA binding protein 0.0191 0.0572 0.0641
Schistosoma mansoni plexin 0.0045 0.0064 0.0063
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0124 0.0702
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0058
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.0071 0.0131
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0092 0.0173
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0036 0.0035 0.0063
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.004 0.0048 0.0052
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.007 0.0151 0.0282
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0079 0.0182 0.0178
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0043 0.0057 0.0053
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0117 0.0115
Trypanosoma cruzi casein kinase, putative 0.0031 0.0016 0.0027
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0216 0.0659 0.1243
Trypanosoma brucei heat shock protein, putative 0.0047 0.0072 0.0404
Giardia lamblia Kinase, NEK 0.0057 0.0105 0.0356
Giardia lamblia Farnesyl diphosphate synthase 0.0051 0.0086 0.0281
Brugia malayi protein kinase C II. 0.0213 0.0647 0.0923
Giardia lamblia Kinase, NEK 0.0057 0.0105 0.0356
Echinococcus granulosus serine:threonine protein kinase PLK1 0.011 0.029 0.0285
Brugia malayi Polyprenyl synthetase family protein 0.0051 0.0086 0.0121
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0074 0.0082
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0176 0.0518 0.0514
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0086 0.0161
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0215 0.0655 0.4846
Echinococcus granulosus glutathione S transferase 0.0054 0.0096 0.0092
Echinococcus multilocularis glutathione S transferase 0.0054 0.0096 0.0092
Echinococcus granulosus cathepsin l1 0.0046 0.0069 0.0064
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0048 0.0075 0.0082
Loa Loa (eye worm) TK/CSK protein kinase 0.0038 0.0041 0.0044
Plasmodium vivax unspecified product 0.0027 0.0002 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0572 0.0571
Brugia malayi SH2 domain containing protein 0.0058 0.0109 0.0153
Leishmania major phosphatidylinositol kinase related protein, putative 0.0061 0.0122 0.1314
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.007 0.0151 0.0284
Trypanosoma cruzi heat shock protein, putative 0.0031 0.0017 0.003
Echinococcus multilocularis protein kinase c epsilon type 0.0213 0.0647 0.0643
Onchocerca volvulus 0.0336 0.1074 0.3216
Entamoeba histolytica cysteine proteinase, putative 0.0046 0.0069 0.0127
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0161 0.0305
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0051 0.0086 0.1477
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Onchocerca volvulus 0.0037 0.0038 0.0093
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0032 0.0019 0.0099
Echinococcus multilocularis N chimaerin 0.0036 0.0035 0.003
Echinococcus multilocularis geminin 0.0344 0.1102 0.1098
Loa Loa (eye worm) phosphatidylinositol 3 0.0061 0.0122 0.0135
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0034 0.0027 0.0028
Echinococcus granulosus heat shock protein 90 0.0047 0.0072 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.011 0.029 0.0288
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0082
Entamoeba histolytica hypothetical protein 0.0061 0.0122 0.0227
Brugia malayi cathepsin L-like precursor 0.0046 0.0069 0.0096
Echinococcus multilocularis cathepsin L cysteine protease 0.0073 0.0161 0.0157
Entamoeba histolytica protein kinase, putative 0.0045 0.0065 0.012
Plasmodium falciparum glycogen synthase kinase 3 0.0078 0.018 0.2253
Echinococcus multilocularis mitogen activated protein kinase 11 0.0195 0.0587 0.0583
Echinococcus multilocularis serine:threonine protein kinase N2 0.0176 0.0518 0.0514
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0406 0.1319 0.1315
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0216 0.0659 0.0655
Plasmodium falciparum calcium-dependent protein kinase 5 0.006 0.0116 0.1442
Echinococcus multilocularis glutathione S transferase 0.0042 0.0053 0.0049
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0031 0.0016 0.0011
Schistosoma mansoni hypothetical protein 0.0344 0.1102 0.1101
Loa Loa (eye worm) hypothetical protein 0.0231 0.0709 0.0794
Trichomonas vaginalis bromodomain-containing protein, putative 0.0026 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0245 0.076 0.0759
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.053 0.1749 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0157 0.0175
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0078 0.018 0.0176
Toxoplasma gondii histone kinase SNF1, putative 0.0048 0.0075 0.0547
Echinococcus multilocularis myosin iiia 0.0036 0.0035 0.003
Brugia malayi Bromodomain containing protein 0.0041 0.0051 0.0071
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.011 0.029 0.0323
Toxoplasma gondii FATC domain-containing protein 0.0092 0.0228 0.1678
Trichomonas vaginalis PIKK family atypical protein kinase 0.0128 0.0352 0.0665
Onchocerca volvulus 0.0215 0.0655 0.1955
Toxoplasma gondii tetratricopeptide repeat-containing protein 0.0215 0.0655 0.4846
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0103 0.0101
Loa Loa (eye worm) hypothetical protein 0.0073 0.0161 0.0179
Entamoeba histolytica protein kinase, putative 0.0031 0.0016 0.0027
Toxoplasma gondii heat shock protein 75, putative 0.0031 0.0017 0.0117
Brugia malayi serine/threonine-protein kinase 6 0.0081 0.0188 0.0267
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0061 0.0122 0.0227
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.2907 1 1
Entamoeba histolytica tyrosin kinase, putative 0.003 0.0013 0.0022
Echinococcus multilocularis protein kinase shaggy 0.0078 0.018 0.0176
Leishmania major cathepsin L-like protease 0.0073 0.0161 0.1747
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0215 0.0655 0.0734
Giardia lamblia Grp94/Hsp90 0.0044 0.0062 0.0183
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0051 0.0097
Schistosoma mansoni protein kinase 0.0028 0.0007 0.0005
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.004 0.0048 0.0044
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0032 0.0019 0.0033
Echinococcus multilocularis cyclin dependent kinase 1 0.0072 0.0158 0.0154
Loa Loa (eye worm) hypothetical protein 0.003 0.0014 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0092 0.0228 0.0323
Onchocerca volvulus Matrix metalloproteinase homolog 0.0168 0.0492 0.1464
Schistosoma mansoni tyrosine kinase 0.0104 0.0269 0.0267
Brugia malayi Neuronal symmetry protein 1 0.0116 0.0313 0.0445
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.006 0.0116 0.0111
Echinococcus granulosus roundabout 2 0.0045 0.0064 0.006
Onchocerca volvulus 0.0055 0.0099 0.0279
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0216 0.0659 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.0794 0.1497
Echinococcus granulosus fibroblast growth factor receptor 4 0.01 0.0256 0.0252
Entamoeba histolytica hypothetical protein 0.1239 0.421 0.7943
Giardia lamblia Kinase, STE STE20 0.0036 0.0035 0.0075
Echinococcus granulosus casein kinase ii subunit alpha 0.0042 0.0056 0.0052
Brugia malayi Plexin repeat family protein 0.0045 0.0064 0.009
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.006 0.0116 0.0655
Onchocerca volvulus 0.0058 0.0109 0.0308
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Echinococcus multilocularis dual specificity 0.0097 0.0245 0.0241
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0062 0.0116
Entamoeba histolytica protein kinase, putative 0.0039 0.0044 0.0081
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0182 0.054 0.0536
Entamoeba histolytica protein kinase domain containing protein 0.003 0.0013 0.0022
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0092 0.0229 0.0325
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0036 0.0033 0.0029
Trypanosoma brucei heat shock protein, putative 0.0047 0.0072 0.0404
Echinococcus multilocularis Immunoglobulin 0.003 0.0013 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0228 0.043
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.006 0.0116 0.0111
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0031 0.0016 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Echinococcus multilocularis tyrosine protein kinase Blk 0.0064 0.0133 0.0128
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0073 0.0161 0.0179
Echinococcus multilocularis plexin a4 0.0053 0.0093 0.0089
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0051 0.0086 0.1477
Schistosoma mansoni cell adhesion molecule 0.0038 0.0041 0.004
Trypanosoma cruzi cysteine proteinase, putative 0.0047 0.0071 0.0131
Trichomonas vaginalis STE family protein kinase 0.0037 0.0036 0.0069
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0047 0.0071 0.0069
Echinococcus granulosus casein kinase I alpha 0.0031 0.0016 0.0011
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0036 0.0035 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Brugia malayi Hr1 repeat family protein 0.0176 0.0518 0.0739
Toxoplasma gondii heat shock protein 90, putative 0.0047 0.0072 0.0522
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0526 0.0993
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0216 0.0659 0.4872
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0163 0.0474 0.047
Echinococcus granulosus protein kinase shaggy 0.0078 0.018 0.0176
Schistosoma mansoni GST class-mu 0.0054 0.0096 0.0095
Brugia malayi P38 map kinase family protein 2 0.0195 0.0587 0.0837
Plasmodium falciparum calcium-dependent protein kinase 1 0.006 0.0116 0.1442
Loa Loa (eye worm) hypothetical protein 0.0038 0.004 0.0043
Schistosoma mansoni hypothetical protein 0.0344 0.1102 0.1101
Echinococcus multilocularis glutathione S transferase 0.0054 0.0096 0.0092
Trichomonas vaginalis CK1 family protein kinase 0.0031 0.0016 0.0029
Leishmania major phosphatidylinositol 4-kinase, putative 0.0061 0.0122 0.1314
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0054 0.0096 0.1032
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0097 0.0245 0.0461
Trypanosoma brucei cysteine peptidase C (CPC) 0.007 0.0151 0.0855
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.1553 0.53 1
Echinococcus multilocularis Immunoglobulin 0.003 0.0013 0.0008
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0122 0.1515
Entamoeba histolytica hypothetical protein 0.0109 0.0286 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0033 0.0063
Entamoeba histolytica PH domain containing protein kinase, putative 0.0042 0.0056 0.0104
Echinococcus multilocularis tyrosine kinase 0.0041 0.0052 0.0048
Leishmania major protein kinase, putative 0.0036 0.0035 0.0364
Toxoplasma gondii target of rapamycin (TOR), putative 0.0228 0.07 0.5176
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0036 0.0035 0.003
Onchocerca volvulus 0.0061 0.0122 0.0347
Echinococcus granulosus c src tyrosine kinase 0.0072 0.0159 0.0154
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Echinococcus multilocularis ephrin type A receptor 4 A 0.0047 0.0072 0.0068
Loa Loa (eye worm) hypothetical protein 0.0032 0.0021 0.0022
Entamoeba histolytica protein kinase, putative 0.006 0.0117 0.0218
Entamoeba histolytica cysteine proteinase 1, putative 0.0047 0.0071 0.0131
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Toxoplasma gondii hypoxia- inducible factor prolyl hydroxylase (phd2), putative 0.0215 0.0655 0.4846
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0037 0.0039 0.0279
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0086 0.107
Schistosoma mansoni hypothetical protein 0.0085 0.0202 0.0201
Loa Loa (eye worm) AGC/PKA protein kinase 0.0032 0.0019 0.0019
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0256 0.0796 0.0792
Echinococcus granulosus NCK adaptor protein 0.0034 0.0027 0.0022
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0109 0.0286 0.0281
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0092 0.0229 1
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0051 0.0086 0.0488
Trypanosoma brucei heat shock protein, putative 0.0047 0.0072 0.0404
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.2907 1 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0181 0.0536 0.101
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0051 0.0086 0.0161
Loa Loa (eye worm) hypothetical protein 0.052 0.1715 0.1924
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1072 0.3629 0.6847
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Echinococcus multilocularis serine:threonine protein kinase 3 0.0104 0.0271 0.0267
Echinococcus multilocularis casein kinase I alpha 0.0031 0.0016 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0001 0.0001
Echinococcus multilocularis cathepsin L 0.0047 0.0071 0.0066
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1553 0.53 0.7575
Trichomonas vaginalis CAMK family protein kinase 0.011 0.029 0.0546
Trypanosoma brucei SNF1-related protein kinases, putative 0.0048 0.0075 0.0423
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0216 0.0659 0.3763
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0128 0.0352 0.3829
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0032 0.0019 0.0014
Schistosoma mansoni heat shock protein 0.0031 0.0017 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0228 0.043
Echinococcus multilocularis rac serine:threonine kinase 0.0267 0.0834 0.083
Leishmania major phosphatidylinositol 3-kinase, putative 0.0216 0.0659 0.7173
Loa Loa (eye worm) matrixin family protein 0.0183 0.0545 0.061
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0035 0.0032 0.0057
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0092 0.0228 0.0224
Brugia malayi Variant SH3 domain containing protein 0.0051 0.0086 0.012
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0056 0.0105
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.053 0.1749 0.3298
Echinococcus multilocularis casein kinase I alpha 0.0031 0.0016 0.0011
Echinococcus multilocularis cathepsin b 0.0181 0.0536 0.0532
Schistosoma mansoni protein kinase 0.0089 0.0217 0.0216
Echinococcus multilocularis fibroblast growth factor receptor 4 0.01 0.0256 0.0252
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0048 0.0075 0.0082
Brugia malayi SRC-1 0.0079 0.0182 0.0259
Echinococcus multilocularis tyrosine protein kinase Srms 0.0064 0.0133 0.0128
Loa Loa (eye worm) hypothetical protein 0.0046 0.0069 0.0075
Trypanosoma brucei heat shock protein, putative 0.0047 0.0072 0.0404
Loa Loa (eye worm) TAR-binding protein 0.0191 0.0572 0.0641
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0057 0.0106 0.0117
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0031 0.0017 0.003
Echinococcus multilocularis glutathione S-transferase 0.0054 0.0096 0.0092
Echinococcus multilocularis serine protein kinase ATM 0.0092 0.0228 0.0224
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0079 0.0182 0.0178
Onchocerca volvulus 0.0031 0.0016 0.0028
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.007 0.0151 0.1629
Echinococcus granulosus defective proboscis extension response 0.003 0.0013 0.0008
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0216 0.0659 0.1241
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0015
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Echinococcus granulosus epidermal growth factor receptor 0.0163 0.0474 0.047
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0073 0.0161 0.0157
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0158 0.0156
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0072 0.0158 0.1162
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0056 0.0105
Brugia malayi Cathepsin L-like precursor 0.0073 0.0161 0.0229
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0161 0.0302
Echinococcus granulosus MAM 0.0085 0.0202 0.0198
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Echinococcus granulosus serine/threonine protein kinase 0.0267 0.0834 0.083
Echinococcus multilocularis 0.0069 0.0147 0.0143
Loa Loa (eye worm) hypothetical protein 0.0101 0.0258 0.0288
Leishmania major hypothetical protein, conserved 0.0051 0.0086 0.0928
Echinococcus multilocularis calcium activated potassium channel 0.004 0.0048 0.0043
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0037 0.0038 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Brugia malayi Tyrosine-protein kinase abl-1 0.0087 0.0211 0.0299
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0074 0.0919
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Plasmodium vivax glycogen synthase kinase 3, putative 0.0078 0.018 0.2253
Echinococcus granulosus tyrosine protein kinase Fyn 0.0079 0.0182 0.0178
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0128 0.0352 0.0501
Trypanosoma brucei cdc2-related kinase 1 0.0072 0.0158 0.0897
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0061 0.0122 0.0227
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Trichomonas vaginalis STE family protein kinase 0.0037 0.0036 0.0069
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0061 0.0122 0.023
Giardia lamblia Kinase, STE STE20 0.0054 0.0096 0.0318
Echinococcus multilocularis rho associated protein kinase 0.0336 0.1074 0.107
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0345 0.1106 0.1102
Echinococcus granulosus casein kinase I delta 0.0031 0.0016 0.0011
Toxoplasma gondii Hsp90 domain-containing protein 0.0178 0.0526 0.3891
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.07 0.1321
Onchocerca volvulus Serine\/threonine kinase homolog 0.011 0.029 0.0853
Toxoplasma gondii cathepsin B 0.007 0.0151 0.1106
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Echinococcus granulosus serine:threonine protein kinase N2 0.0176 0.0518 0.0514
Loa Loa (eye worm) TK/ALK protein kinase 0.0728 0.2436 0.2732
Loa Loa (eye worm) TK/FAK protein kinase 0.0167 0.049 0.0548
Echinococcus granulosus aurora kinase A 0.0081 0.0188 0.0184
Brugia malayi Stress-activated protein kinase jnk-1 0.0345 0.1106 0.1579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0128 0.0352 0.0665
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0081 0.0188 0.0353
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0079 0.0182 0.0178
Schistosoma mansoni protein kinase subunit beta 0.0058 0.0112 0.011
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0147 0.042 0.2398
Echinococcus multilocularis RNA directed DNA polymerase 0.0036 0.0034 0.003
Echinococcus granulosus serine:threonine protein kinase 0.0048 0.0075 0.0071
Plasmodium falciparum calcium-dependent protein kinase 3 0.006 0.0116 0.1442
Loa Loa (eye worm) hypothetical protein 0.0036 0.0033 0.0036
Plasmodium falciparum glutathione S-transferase 0.0054 0.0096 0.1196
Trypanosoma brucei Casein kinase II 0.0042 0.0056 0.0312
Leishmania major ATPase, putative 0.0029 0.0008 0.0078
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0041 0.0052 0.0048
Entamoeba histolytica protein kinase domain containing protein 0.0078 0.018 0.0338
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0159 0.0157
Leishmania major hypothetical protein, conserved 0.0061 0.0122 0.1314
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0092 0.0228 0.0428
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0002 0.0001
Trypanosoma cruzi polo-like protein kinase, putative 0.011 0.029 0.0544
Echinococcus granulosus unc 13 munc13 0.0037 0.0038 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0079 0.0183 0.0532
Trypanosoma cruzi casein kinase, putative 0.0031 0.0016 0.0027
Plasmodium vivax unspecified product 0.0047 0.0071 0.0874
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0092 0.0229 0.0326
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Giardia lamblia Kinase, NEK 0.0057 0.0105 0.0356
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0079 0.0183 0.0204
Echinococcus granulosus tyrosine protein kinase ABL1 0.0123 0.0337 0.0333
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0061 0.0122 0.0117
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.0995 0.0993
Echinococcus granulosus N chimaerin 0.0036 0.0035 0.003
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.006 0.0116 0.0111
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0004 0.0007
Echinococcus granulosus tar DNA binding protein 0.0191 0.0572 0.0568
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0256 0.0796 1
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0082 0.0194 0.019
Onchocerca volvulus Alicorn homolog 0.0051 0.0086 0.0239
Brugia malayi RhoGAP domain containing protein 0.0036 0.0035 0.0047
Leishmania major cathepsin L-like protease 0.0073 0.0161 0.1747
Loa Loa (eye worm) AGC/NDR protein kinase 0.0176 0.0518 0.058
Plasmodium falciparum casein kinase 2, alpha subunit 0.0042 0.0056 0.0686
Schistosoma mansoni tyrosine kinase 0.0072 0.0159 0.0157
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0291 0.0918 0.5246
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0061 0.0122 0.1515
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.0058 0.0112 0.0123
Trichomonas vaginalis glutaminyl-tRNA synthetase, putative 0.0042 0.0053 0.0101
Brugia malayi Cathepsin L-like precursor 0.0073 0.0161 0.0229
Echinococcus multilocularis casein kinase I delta 0.0031 0.0016 0.0011
Loa Loa (eye worm) hypothetical protein 0.0044 0.0061 0.0066
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.053 0.1749 0.33
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0012
Loa Loa (eye worm) phosphatidylinositol 3 0.2593 0.891 1
Echinococcus granulosus cyclin dependent kinase 1 0.0072 0.0158 0.0154
Schistosoma mansoni hypothetical protein 0.0029 0.0008 0.0007
Plasmodium falciparum heat shock protein 90 0.0047 0.0072 0.0887
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0056 0.0105
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Plasmodium falciparum calcium-dependent protein kinase 2 0.006 0.0116 0.1442
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0572 0.0571
Loa Loa (eye worm) TK protein kinase 0.0064 0.0133 0.0147
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Brugia malayi Temporarily assigned gene name protein 59 0.0051 0.0086 0.0121
Schistosoma mansoni atypical protein kinase C 0.0227 0.0698 0.0697
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0086 0.107
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0092 0.0228 0.0323
Loa Loa (eye worm) hypothetical protein 0.0055 0.0099 0.011
Onchocerca volvulus 0.0073 0.0161 0.0466
Brugia malayi Cam kinase protein 1 0.006 0.0116 0.0163
Brugia malayi map kinase activated protein kinase protein 2 0.0252 0.0782 0.1116
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0075 0.0073
Brugia malayi Glutathione S-transferase 4 0.0042 0.0053 0.0074
Brugia malayi glutathione transferase 0.0054 0.0096 0.0135
Trypanosoma cruzi casein kinase II, putative 0.0042 0.0056 0.0103
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.004 0.0073
Loa Loa (eye worm) TK protein kinase 0.0107 0.0279 0.0312
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0092 0.0228 0.1296
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0064 0.0133 0.0128
Trichomonas vaginalis endoplasmin, putative 0.0034 0.0027 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.07 0.1321
Entamoeba histolytica protein kinase, putative 0.0081 0.0188 0.0353
Trichomonas vaginalis CK1 family protein kinase 0.0031 0.0016 0.0029
Echinococcus multilocularis neuropeptide s receptor 0.0462 0.1512 0.1509
Plasmodium vivax vivapain-2 0.0073 0.0161 0.2015
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0038 0.004 0.0038
Trypanosoma brucei heat shock protein 84, putative 0.0031 0.0017 0.0091
Giardia lamblia Heat shock protein HSP 90-alpha 0.004 0.0048 0.0129
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1553 0.53 1
Loa Loa (eye worm) TK/ABL protein kinase 0.0123 0.0337 0.0377
Schistosoma mansoni cathepsin F (C01 family) 0.0046 0.0069 0.0067
Leishmania major heat shock protein, putative 0.0031 0.0017 0.0173
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0079 0.0182 0.0178
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0056 0.0102 0.01
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Brugia malayi Protein kinase domain 0.0037 0.0036 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0079 0.0077
Echinococcus granulosus casein kinase I alpha 0.0031 0.0016 0.0011
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0215 0.0655 0.1234
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0032 0.0019 0.0014
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0051 0.0086 0.0094
Brugia malayi hypothetical protein 0.2042 0.6996 1
Trypanosoma brucei heat shock protein, putative 0.0047 0.0072 0.0404
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0054 0.0096 0.0541
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0116 0.0114
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0291 0.0918 0.5246
Loa Loa (eye worm) heat shock protein 75 0.0031 0.0017 0.0017
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Loa Loa (eye worm) phosphatidylinositol 3 0.0061 0.0122 0.0135
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.01 0.0256 0.0252
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0518 0.0517
Brugia malayi MAP kinase sur-1 0.0062 0.0124 0.0175
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0036 0.0035 0.0033
Brugia malayi isocitrate dehydrogenase 0.0048 0.0074 0.0104
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0252 0.0782 0.0778
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0042 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0161 0.0302
Entamoeba histolytica protein kinase, putative 0.0035 0.0032 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.1106 0.1105
Schistosoma mansoni protein kinase 0.0116 0.0313 0.0311
Trichomonas vaginalis CAMK family protein kinase 0.011 0.029 0.0546
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0041 0.0052 0.0048
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0176 0.0518 0.0514
Trypanosoma cruzi cdc2-related kinase 1 0.0072 0.0158 0.0296
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0051 0.0086 0.0161
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0051 0.0086 0.0163
Brugia malayi serine/threonine-protein kinase PAK 7 0.0095 0.0237 0.0337
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0038 0.004 0.0055
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.012 0.0326 0.0322
Echinococcus granulosus growth factor receptor bound protein 2 0.0034 0.0027 0.0022
Echinococcus multilocularis tyrosine protein kinase csk 0.0038 0.0041 0.0037
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0345 0.1106 0.124
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0291 0.0918 0.173
Echinococcus granulosus serine:threonine protein kinase 3 0.0104 0.0271 0.0267
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0526 0.0993
Schistosoma mansoni nephrin 0.0038 0.0039 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0183 0.0181
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1553 0.53 1
Schistosoma mansoni protein kinase 0.0037 0.0036 0.0035
Brugia malayi Hsp90 protein 0.0031 0.0017 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0518 0.0517
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Schistosoma mansoni vav2 0.0047 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.005 0.0082 0.0091
Giardia lamblia Kinase, PLK 0.011 0.029 0.1086
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0079 0.0183 0.0179
Brugia malayi Protein kinase domain containing protein 0.004 0.0048 0.0066
Mycobacterium tuberculosis Conserved hypothetical protein 0.0061 0.0122 0.3579
Echinococcus multilocularis cyclin dependent kinase 7 0.0049 0.0079 0.0074
Brugia malayi cyclin-dependent kinase 7 homolog 0.0049 0.0079 0.011
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0124 0.1337
Echinococcus granulosus Glutaredoxin protein 5 0.024 0.0741 0.0737
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0032 0.0019 0.0014
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Echinococcus multilocularis unc 13 (munc13) 0.0037 0.0038 0.0033
Onchocerca volvulus Tyrosine kinase homolog 0.0221 0.0674 0.2013
Loa Loa (eye worm) TK/ROR protein kinase 0.0028 0.0007 0.0006
Echinococcus granulosus tyrosine kinase 0.0041 0.0052 0.0048
Brugia malayi Protein kinase domain containing protein 0.0313 0.0995 0.142
Leishmania major cathepsin L-like protease 0.0073 0.0161 0.1747
Echinococcus granulosus endoplasmin 0.0044 0.0062 0.0057
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.0058 0.0112 0.0631
Plasmodium vivax heat shock protein 86, putative 0.0047 0.0072 0.0887
Schistosoma mansoni tyrosine kinase 0.0163 0.0474 0.0473
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Treponema pallidum heat shock protein 90 0.0044 0.0062 0.5
Entamoeba histolytica protein kinase, putative 0.0415 0.1351 0.2547
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0074 0.007
Brugia malayi heat shock protein 90 0.0047 0.0072 0.01
Entamoeba histolytica protein kinase, putative 0.0176 0.0518 0.0976
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.053 0.1749 0.33
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0181 0.0536 0.0535
Leishmania major cathepsin L-like protease 0.0073 0.0161 0.1747
Brugia malayi loechrig isoform VII 0.012 0.0326 0.0464
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.017 0.05 0.0943
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0246 0.0762 0.0854
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0019 0.0035
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0081 0.0188 0.0353
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0188 0.0355
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0061 0.0122 0.0227
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0124 0.012
Loa Loa (eye worm) endoplasmin 0.0047 0.0072 0.0079
Schistosoma mansoni unc-13 (munc13) 0.0037 0.0038 0.0036
Loa Loa (eye worm) phosphatidylinositol 3 0.0061 0.0122 0.0135
Toxoplasma gondii 5'-AMP-activated protein kinase subunit beta-1 family protein, putative 0.0034 0.0028 0.0202
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.006 0.0116 0.1442
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.007 0.0151 0.0149
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0036 0.0035 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0048 0.0046
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0074 0.0541
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0048 0.0075 0.0071
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0097 0.0245 0.2663
Trypanosoma cruzi target of rapamycin kinase 3 0.0241 0.0745 0.1403
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0031 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.0016
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.0071 0.0131
Echinococcus multilocularis casein kinase ii subunit alpha 0.0042 0.0056 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0772 0.0771
Loa Loa (eye worm) SRC-1 0.0079 0.0182 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0019 0.0017
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0081 0.0188 0.0184
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0034 0.0027 0.0025
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0061 0.0122 0.0892
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0117 0.0115
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0081 0.0188 0.0184
Trichomonas vaginalis STE family protein kinase 0.0037 0.0036 0.0069
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0124 0.0234
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0124 0.0231
Schistosoma mansoni Neurotrimin precursor (hNT) 0.003 0.0013 0.0011
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0079 0.0183 0.0179
Echinococcus granulosus cathepsin L 0.0047 0.0071 0.0066
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0048 0.0076 0.0083
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0116 0.3233
Brugia malayi putative serine/threonine kinase SADA gamma 0.0048 0.0075 0.0105
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0074 0.007
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0051 0.0086 0.1072
Entamoeba histolytica cysteine proteinase 2 0.0047 0.0071 0.0131
Onchocerca volvulus 0.0086 0.0206 0.06
Entamoeba histolytica protein kinase, putative 0.0037 0.0036 0.0066
Plasmodium vivax vivapain-2 0.0073 0.0161 0.2015
Schistosoma mansoni ste20-related kinase 0.0084 0.02 0.0198
Trypanosoma brucei heat shock protein 90, putative 0.0047 0.0072 0.0404
Trypanosoma cruzi cdc2-related kinase 1 0.0072 0.0158 0.0296
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Brugia malayi Protein kinase c protein 2 0.0089 0.0218 0.0309
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0074 0.007
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0057 0.0105 0.0771
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0161 0.0302
Schistosoma mansoni tyrosine kinase 0.0056 0.0102 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0216 0.0659 0.1241
Giardia lamblia Hypothetical protein 0.0061 0.0122 0.0421
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0124 0.0429
Plasmodium vivax hypothetical protein 0.0061 0.0122 0.1515
Brugia malayi ATPase, AAA family protein 0.0034 0.0026 0.0035
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0191 0.0572 0.0641
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0216 0.0659 0.1243
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Schistosoma mansoni transcription factor LCR-F1 0.0109 0.0286 0.0284
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0124 0.0137
Onchocerca volvulus Matrilysin homolog 0.0168 0.0492 0.1464
Echinococcus granulosus neuropeptide s receptor 0.0462 0.1512 0.1509
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0036 0.0034 0.003
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0116 0.0112
Trypanosoma cruzi casein kinase, putative 0.0031 0.0016 0.0027
Brugia malayi prolyl 4-hydroxylase 0.0215 0.0655 0.0935
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0104 0.0271 0.0302
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0037 0.0039 0.0216
Schistosoma mansoni serine/threonine kinase 0.0176 0.0518 0.0517
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0188 0.0355
Brugia malayi phosphoinositide-dependent protein kinase I 0.006 0.0117 0.0165
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.006 0.0116 0.0111
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0031 0.0017 0.0013
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Echinococcus multilocularis casein kinase i 0.0031 0.0016 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0116 0.0114
Leishmania major cathepsin L-like protease 0.0073 0.0161 0.1747
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0572 0.0571
Brugia malayi Variant SH3 domain containing protein 0.0036 0.0035 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0027 0.0001 0.0002
Echinococcus multilocularis serine:threonine protein kinase 38 0.0176 0.0518 0.0514
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0019
Plasmodium falciparum cysteine proteinase falcipain 1 0.0047 0.0071 0.0874
Brugia malayi Bromodomain containing protein 0.0041 0.0051 0.0071
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.006 0.0117 0.0113
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0038 0.004 0.0075
Echinococcus multilocularis serine threonine protein kinase 0.0232 0.0715 0.0711
Trypanosoma cruzi casein kinase, putative 0.0031 0.0016 0.0027
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0036 0.0035 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0015 0.0028
Echinococcus granulosus dnaJ subfamily B 0.0402 0.1304 0.13
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Onchocerca volvulus 0.0073 0.0161 0.0466
Echinococcus multilocularis 0.0061 0.0122 0.0117
Echinococcus granulosus calcium activated potassium channel 0.004 0.0048 0.0043
Trypanosoma brucei protein kinase, putative 0.0037 0.0039 0.0216
Brugia malayi Sex muscle abnormal protein 5 0.0034 0.0027 0.0036
Onchocerca volvulus 0.0073 0.0161 0.0466
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0099 0.0252 0.0248
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.006 0.0116 0.0128
Schistosoma mansoni hypothetical protein 0.0109 0.0286 0.0284
Trichomonas vaginalis AGC family protein kinase 0.0027 0.0001 0.0002
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0291 0.0918 1
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0061 0.0122 0.0117
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0112 0.0822
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0034 0.0026 0.0022
Echinococcus multilocularis cpg binding protein 0.003 0.0012 0.0008
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.053 0.1749 0.3298
Entamoeba histolytica protein kinase 2, putative 0.0256 0.0796 0.15
Brugia malayi Cathepsin L-like precursor 0.0046 0.0069 0.0096
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Schistosoma mansoni tyrosine kinase 0.0034 0.0027 0.0026
Schistosoma mansoni protein kinase 0.0099 0.0252 0.0251
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0256 0.0796 0.15
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0038 0.004 0.0221
Echinococcus multilocularis casein kinase I delta 0.0031 0.0016 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Echinococcus multilocularis heat shock protein 90 0.004 0.0048 0.0044
Echinococcus granulosus Protein kinase C brain isozyme 0.0249 0.0772 0.0769
Brugia malayi SH2 domain containing protein 0.0041 0.0052 0.0072
Schistosoma mansoni ephrin receptor 0.0047 0.0072 0.007
Trypanosoma cruzi heat shock protein 85, putative 0.004 0.0048 0.0089
Loa Loa (eye worm) hypothetical protein 0.0037 0.0038 0.0041
Loa Loa (eye worm) PEK/PEK protein kinase 0.0089 0.0217 0.0242
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0073 0.0161 0.0179
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0074 0.0749
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Schistosoma mansoni heat shock protein 0.0047 0.0072 0.007
Entamoeba histolytica protein kinase , putative 0.0081 0.0188 0.0353
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Giardia lamblia Kinase, CMGC GSK 0.0078 0.018 0.0653
Loa Loa (eye worm) polyprenyl synthetase 0.0051 0.0086 0.0095
Brugia malayi protein kinase C3,putative 0.0065 0.0135 0.0191
Trypanosoma cruzi casein kinase, putative 0.0031 0.0016 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0103 0.0101
Loa Loa (eye worm) hypothetical protein 0.0092 0.0229 0.0256
Echinococcus granulosus calcium dependent protein kinase 0.0044 0.0061 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0744 0.1403
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.0071 0.0131
Loa Loa (eye worm) AGC/AKT protein kinase 0.0426 0.1389 0.1557
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0038 0.004 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0744 0.1403
Trichomonas vaginalis STE family protein kinase 0.0054 0.0096 0.0181
Entamoeba histolytica casein kinase, putative 0.0042 0.0056 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0071 0.0397
Onchocerca volvulus 0.0042 0.0053 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0784 0.0782
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0252 0.0784 0.078
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Brugia malayi hypothetical protein 0.0033 0.0023 0.0031
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0061 0.0122 0.012
Echinococcus granulosus glutathione S transferase Mu 1 0.0054 0.0096 0.0092
Plasmodium falciparum serine/threonine protein kinase KIN 0.0048 0.0075 0.0929
Echinococcus granulosus glutathione S transferase 0.0042 0.0053 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0078 0.018 0.0338
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0228 0.07 0.0696
Onchocerca volvulus 0.0041 0.0052 0.0137
Echinococcus multilocularis nervana 2 0.024 0.0741 0.0737
Plasmodium falciparum protein kinase 5 0.0072 0.0158 0.1972
Loa Loa (eye worm) hypothetical protein 0.0055 0.0099 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0124 0.0122
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0047 0.0071 0.0069
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0082 0.0194 0.019
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0116 0.085
Loa Loa (eye worm) hypothetical protein 0.05 0.1645 0.1845
Schistosoma mansoni tyrosine kinase 0.0163 0.0474 0.0473
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0047 0.0071 0.0069
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0188 0.0353
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Onchocerca volvulus 0.0073 0.0161 0.0466
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.006 0.0117 0.0112
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0074 0.0104
Schistosoma mansoni growth factor receptor-bound protein 0.0034 0.0027 0.0025
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0037 0.0036 0.0032
Toxoplasma gondii cathepsin CPL 0.0073 0.0161 0.1187
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0215 0.0655 0.0651
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0034 0.0026 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0426 0.1389 0.262
Brugia malayi serine/threonine-protein kinase plk-2 0.011 0.029 0.0412
Echinococcus multilocularis cyclin dependent kinase 1 0.0072 0.0158 0.0154
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0252 0.0784 0.078
Brugia malayi Casein kinase II, alpha chain 0.0042 0.0056 0.0077
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0032 0.0019 0.0014
Brugia malayi Protein kinase domain containing protein 0.0041 0.0052 0.0072
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0031 0.0016 0.0027
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0048 0.0075 0.0929
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Brugia malayi Protein kinase domain containing protein 0.0041 0.0052 0.0072
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.003 0.0013 0.0011
Echinococcus granulosus raf serine:threonine protein kinase 0.0038 0.0042 0.0038
Onchocerca volvulus 0.006 0.0116 0.0331
Echinococcus multilocularis cathepsin L cysteine protease 0.0073 0.0161 0.0157
Giardia lamblia Kinase, CMGC CDK 0.0072 0.0158 0.0565
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0074 0.0418
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0216 0.0659 0.094
Schistosoma mansoni hypothetical protein 0.0061 0.0122 0.012
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Echinococcus multilocularis activin receptor type 0.0037 0.0039 0.0035
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0128 0.0352 0.0662
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0228 0.07 0.0696
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.0058 0.0112 0.0381
Echinococcus granulosus dual specificity 0.0097 0.0245 0.0241
Echinococcus multilocularis nervana 2 0.024 0.0741 0.0737
Loa Loa (eye worm) cathepsin B 0.007 0.0151 0.0167
Echinococcus granulosus serine:threonine kinase SAD 1 0.0048 0.0075 0.0071
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0161 0.0302
Giardia lamblia Cathepsin B precursor 0.007 0.0151 0.0535
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0128 0.0352 0.0348
Echinococcus multilocularis aurora kinase A 0.0081 0.0188 0.0184
Trypanosoma cruzi cdc2-related kinase 3 0.0072 0.0158 0.0296
Brugia malayi Endoplasmin precursor 0.0047 0.0072 0.01
Schistosoma mansoni protein kinase C mu 0.0065 0.0134 0.0132
Echinococcus multilocularis MAM 0.0085 0.0202 0.0198
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0041 0.0052 0.0096
Brugia malayi Protein kinase domain containing protein 0.1011 0.3417 0.4883
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0526 0.0992
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0072 0.0159 0.0155
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0048 0.0075 0.0139
Echinococcus multilocularis tyrosine protein kinase csk 0.0038 0.0041 0.0037
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0028 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0051 0.0056
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Echinococcus granulosus tyrosine protein kinase csk 0.0038 0.0041 0.0037
Entamoeba histolytica protein kinase, putative 0.0078 0.018 0.0338
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0279 0.0397
Echinococcus granulosus protein kinase c epsilon type 0.0213 0.0647 0.0643
Giardia lamblia Phosphatidylinositol 4-kinase 0.0061 0.0122 0.0421
Schistosoma mansoni protein kinase 0.0042 0.0056 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.021 0.0638 0.1203
Trichomonas vaginalis AGC family protein kinase 0.0057 0.0105 0.0199
Schistosoma mansoni cpg binding protein 0.0028 0.0007 0.0005
Brugia malayi Protein kinase domain containing protein 0.0167 0.049 0.0698
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0161 0.0302
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0176 0.0518 0.0514
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0036 0.0033 0.0029
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0276 0.0866 0.0862
Loa Loa (eye worm) hypothetical protein 0.0046 0.0069 0.0075
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0079 0.0182 0.0178
Loa Loa (eye worm) hypothetical protein 0.0085 0.0202 0.0225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0744 0.1403
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0123 0.0337 0.0333
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0572 0.0571
Loa Loa (eye worm) hypothetical protein 0.0034 0.0027 0.0028
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0291 0.0918 0.173
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0086 0.0487
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0036 0.0035 0.0063
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.1012 0.342 0.3417
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Entamoeba histolytica protein kinase domain containing protein 0.0097 0.0245 0.0461
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0061 0.0122 0.0172
Onchocerca volvulus 0.0046 0.0069 0.0187
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0032 0.0019 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0161 0.0302
Echinococcus multilocularis Zinc finger, PHD finger 0.0216 0.0659 0.0655
Plasmodium falciparum endoplasmin, putative 0.0034 0.0027 0.0325
Loa Loa (eye worm) TK protein kinase 0.0045 0.0065 0.0071
Brugia malayi hypothetical protein 0.0032 0.002 0.0027
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0124 0.0231
Loa Loa (eye worm) hypothetical protein 0.0622 0.2067 0.2318
Entamoeba histolytica hypothetical protein 0.0109 0.0286 0.0537
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.1304 0.13
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0782 0.078
Loa Loa (eye worm) phosphatidylinositol 3 0.0291 0.0918 0.1029
Echinococcus multilocularis protein kinase c iota type 0.0225 0.069 0.0686
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1011 0.3417 0.3834
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.1492 0.5087 0.9598
Toxoplasma gondii AGC kinase 0.0032 0.0019 0.0128
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0012
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0078 0.018 0.0179
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0061 0.0122 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0075 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0116 0.0218
Echinococcus multilocularis mitogen activated protein kinase 11 0.0195 0.0587 0.0583
Loa Loa (eye worm) loechrig isoform VII 0.012 0.0326 0.0365
Brugia malayi Protein kinase domain containing protein 0.0079 0.0183 0.0259
Schistosoma mansoni tyrosine kinase 0.0141 0.0399 0.0397
Schistosoma mansoni protein kinase 0.0089 0.0217 0.0216
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0007 0.0006
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0128 0.0352 0.0348
Schistosoma mansoni glutathione-S-transferase 0.0054 0.0096 0.0095
Loa Loa (eye worm) hypothetical protein 0.0045 0.0064 0.0071
Brugia malayi hypothetical protein 0.0041 0.0052 0.0072
Plasmodium vivax heat shock protein, putative 0.0178 0.0526 0.6606
Echinococcus granulosus AMPK beta subunit 0.0058 0.0112 0.0107
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0051 0.0086 0.0082
Loa Loa (eye worm) hypothetical protein 0.0055 0.0099 0.011
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0062 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Entamoeba histolytica protein kinase domain containing protein 0.0042 0.0056 0.0103
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.004 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.004 0.0048 0.009
Echinococcus granulosus RNA directed DNA polymerase 0.0036 0.0034 0.003
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0291 0.0918 0.0914
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0086 0.107
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0216 0.0659 0.4872
Loa Loa (eye worm) hypothetical protein 0.0215 0.0655 0.0734
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0056 0.0105
Entamoeba histolytica hypothetical protein 0.0109 0.0286 0.0537
Loa Loa (eye worm) hypothetical protein 0.0034 0.0026 0.0028
Trypanosoma brucei protein kinase, putative 0.0062 0.0124 0.0702
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0116 0.3233
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0124 0.012
Loa Loa (eye worm) hypothetical protein 0.0075 0.0167 0.0186
Entamoeba histolytica heat shock protein 90, putative 0.0047 0.0072 0.0133
Brugia malayi Protein kinase domain containing protein 0.0041 0.0052 0.0072
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.053 0.1749 0.2498
Echinococcus multilocularis epidermal growth factor receptor 0.0245 0.076 0.0756
Schistosoma mansoni tyrosine kinase 0.01 0.0256 0.0255
Plasmodium vivax protein kinase Crk2 0.0072 0.0158 0.1972
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.0058 0.0112 0.0208
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0051 0.0097
Giardia lamblia Aurora kinase 0.0081 0.0188 0.0684
Echinococcus multilocularis epidermal growth factor receptor 0.0163 0.0474 0.047
Trichomonas vaginalis AGC family protein kinase 0.0027 0.0001 0.0002
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.006 0.0116 0.1442
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0038 0.004 0.0035
Toxoplasma gondii heat shock protein HSP90 0.0047 0.0072 0.0522
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Echinococcus granulosus protein tyrosine kinase 0.0166 0.0484 0.048
Plasmodium falciparum heat shock protein 90, putative 0.0027 0.0004 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0744 0.1403
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0122 0.023
Entamoeba histolytica protein kinase, putative 0.0426 0.1389 0.2619
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0291 0.0918 1
Echinococcus multilocularis raf serine:threonine protein kinase 0.0038 0.0042 0.0038
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0313 0.0995 0.1115
Brugia malayi cathepsin B-like cysteine proteinase 0.0181 0.0536 0.0764
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Trypanosoma brucei 2OG-Fe(II) oxygenase superfamily, putative 0.0215 0.0655 0.3743
Echinococcus granulosus casein kinase i 0.0031 0.0016 0.0011
Echinococcus granulosus heat shock protein 0.0047 0.0072 0.0067
Echinococcus granulosus glutathione S transferase 0.0185 0.0549 0.0545
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0051 0.0086 0.0082
Echinococcus granulosus bromodomain containing 2 0.0041 0.0051 0.0047
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0031 0.0017 0.0031
Echinococcus granulosus protein kinase c iota type 0.0225 0.069 0.0686
Trypanosoma brucei protein kinase, putative 0.0078 0.018 0.1025
Entamoeba histolytica casein kinase, putative 0.0031 0.0016 0.0027
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0375 0.1212 0.474
Loa Loa (eye worm) AGC/PKN protein kinase 0.0176 0.0518 0.058
Brugia malayi serine/threonine protein kinase 6 0.0081 0.0188 0.0267
Trichomonas vaginalis heat shock protein, putative 0.004 0.0048 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0111 0.0295 0.0557
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0016 0.0014
Brugia malayi C1-like domain containing protein 0.0065 0.0134 0.0189
Schistosoma mansoni hypothetical protein 0.0085 0.0202 0.0201
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Echinococcus granulosus heat shock protein 90 0.004 0.0048 0.0044
Plasmodium falciparum heat shock protein 90, putative 0.0178 0.0526 0.6606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0072 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.011 0.029 0.0546
Entamoeba histolytica hypothetical protein 0.0092 0.0228 0.0428
Onchocerca volvulus 0.0061 0.0122 0.0347
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Onchocerca volvulus 0.0076 0.0172 0.0498
Trichomonas vaginalis PIKK family atypical protein kinase 0.0205 0.0619 0.1169
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.004 0.0049 0.0047
Leishmania major protein kinase A catalytic subunit 0.0032 0.0019 0.0189
Schistosoma mansoni protein kinase 0.0099 0.0252 0.0251
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0276 0.0866 0.0862
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0032 0.0019 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0426 0.1389 0.262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0526 0.0992
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0032 0.0019 0.0218
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.006 0.0117 0.0113
Plasmodium vivax unspecified product 0.0042 0.0056 0.0686
Onchocerca volvulus Cathepsin L homolog 0.0073 0.0161 0.0466
Loa Loa (eye worm) SH2 domain-containing protein 0.0036 0.0034 0.0036
Loa Loa (eye worm) AGC/PKA protein kinase 0.0032 0.0019 0.0019
Echinococcus granulosus dual specificity mitogen activated protein 0.0054 0.0096 0.0092
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0097 0.0245 0.0461
Schistosoma mansoni tyrosine kinase 0.0155 0.0445 0.0444
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.0048 0.0089
Loa Loa (eye worm) transcription factor SMAD2 0.0354 0.1138 0.1276
Onchocerca volvulus 0.0032 0.0021 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0186 0.0555 0.1047
Loa Loa (eye worm) hypothetical protein 0.0054 0.0096 0.0106
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0092 0.0228 0.0428
Trypanosoma cruzi cdc2-related kinase 3 0.0072 0.0158 0.0296
Schistosoma mansoni tyrosine kinase 0.0079 0.0182 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.011 0.029 0.0546
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0044 0.0062 0.5
Onchocerca volvulus 0.0073 0.0161 0.0466
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Entamoeba histolytica protein kinase domain containing protein 0.0037 0.0039 0.0071
Entamoeba histolytica protein kinase, putative 0.006 0.0116 0.0216
Brugia malayi hypothetical protein 0.0109 0.0286 0.0406
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0019 0.0017
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0031 0.0016 0.0016
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0081 0.0188 0.0353
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0037 0.0039 0.0071
Echinococcus granulosus tyrosine protein kinase csk 0.0038 0.0041 0.0037
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0051 0.0086 0.0085
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0228 0.07 0.0999
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0054 0.0096 0.0135
Trypanosoma brucei cdc2-related kinase 3 0.0072 0.0158 0.0897
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0086 0.0161
Onchocerca volvulus 0.0384 0.124 0.3719
Schistosoma mansoni unc-13 (munc13) 0.0043 0.0058 0.0056
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.011 0.029 0.0285
Brugia malayi Protein kinase domain containing protein 0.0728 0.2437 0.3482
Echinococcus multilocularis cysteine protease 0.0073 0.0161 0.0157
Plasmodium falciparum cysteine proteinase falcipain 3 0.0073 0.0161 0.2015
Loa Loa (eye worm) heat shock protein 90 0.0047 0.0072 0.0079
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.0071 0.0131
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0061 0.0122 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0192 0.0575 0.1086
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0185 0.0551 0.0786
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0071 0.0397
Trichomonas vaginalis PIKK family atypical protein kinase 0.0128 0.0352 0.0665
Trypanosoma cruzi polo-like protein kinase, putative 0.011 0.029 0.0544
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0116 0.0313 0.0309
Trypanosoma brucei rac serine-threonine kinase, putative 0.0426 0.1389 0.794
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0032 0.0019 0.0014
Onchocerca volvulus 0.0078 0.018 0.0523
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0056 0.0103 0.0099
Leishmania major hypothetical protein, conserved 0.0058 0.0112 0.1204
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0036 0.0035 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0073 0.0161 0.0305
Schistosoma mansoni serine/threonine kinase 0.004 0.0048 0.0046
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0061 0.0122 0.0117
Echinococcus granulosus tyrosine protein kinase HCK 0.0045 0.0065 0.006
Brugia malayi Hemopexin family protein 0.0107 0.0282 0.0401
Plasmodium vivax heat shock protein 90, putative 0.0031 0.0017 0.0199
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0038 0.004 0.0035
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0097 0.0245 0.0274
Plasmodium vivax vivapain-3 0.0047 0.0071 0.0874
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0032 0.0019 0.0128
Loa Loa (eye worm) matrix metalloproteinase 0.0076 0.0172 0.0191
Brugia malayi casein kinase I 0.0031 0.0016 0.002
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0072 0.0159 0.0155
Echinococcus multilocularis glutathione S transferase 0.0054 0.0096 0.0092
Entamoeba histolytica protein kinase, putative 0.0097 0.0245 0.0461
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0021
Onchocerca volvulus 0.0041 0.0052 0.0137
Loa Loa (eye worm) MH2 domain-containing protein 0.0354 0.1138 0.1276
Brugia malayi Protein kinase domain containing protein 0.0384 0.124 0.1771
Trypanosoma cruzi Protein kinase B 0.0267 0.0834 0.1571
Mycobacterium leprae conserved hypothetical protein 0.0061 0.0122 0.3579
Leishmania major cathepsin L-like protease 0.0073 0.0161 0.1747
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.006 0.0117 0.0129
Brugia malayi Cathepsin L-like precursor 0.0073 0.0161 0.0229
Brugia malayi Matrixin family protein 0.0183 0.0545 0.0777
Schistosoma mansoni protein kinase 0.006 0.0116 0.0114
Loa Loa (eye worm) hypothetical protein 0.0542 0.1789 0.2006
Onchocerca volvulus 0.0045 0.0064 0.0174
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0239 0.0737 0.0733
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0092 0.0228 0.0428
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0092 0.0173
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0075 0.0423
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1032 0.3491 0.4989
Loa Loa (eye worm) hypothetical protein 0.0056 0.0103 0.0114
Echinococcus granulosus tyrosine protein kinase Fyn 0.0079 0.0182 0.0178
Schistosoma mansoni adapter molecule crk 0.0034 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0038 0.0041
Leishmania major cathepsin L-like protease 0.0073 0.0161 0.1747
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0037 0.0038 0.0071
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Entamoeba histolytica cell division protein kinase 2, putative 0.0072 0.0158 0.0296
Schistosoma mansoni protein kinase 0.0031 0.0016 0.0014
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0128 0.0352 0.0662
Entamoeba histolytica protein kinase, putative 0.0081 0.0188 0.0353
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0251 0.078 0.0874
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0079 0.0182 0.0178
Loa Loa (eye worm) hypothetical protein 0.0208 0.063 0.0705
Toxoplasma gondii AGC kinase 0.0415 0.1351 1
Echinococcus granulosus intersectin 2 0.0035 0.003 0.0025
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0124 0.0231
Echinococcus granulosus tyrosine protein kinase Src64B 0.0079 0.0182 0.0178
Entamoeba histolytica protein kinase, putative 0.0097 0.0245 0.0461
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0072 0.0159 0.0155
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.006 0.0116 0.1442
Entamoeba histolytica hypothetical protein 0.0061 0.0122 0.0227
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0056 0.0105
Loa Loa (eye worm) hypothetical protein 0.0053 0.0092 0.0101
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0252 0.0782 0.0778
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.053 0.1749 0.3298
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0551 0.182 0.1819
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0245 0.0244
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.0058 0.0112 0.0157
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.018 0.034
Echinococcus granulosus twitchin 0.0052 0.009 0.0086
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0097 0.0246 0.1815
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0215 0.0655 0.0654
Schistosoma mansoni vesicular amine transporter 0.003 0.0013 0.0011
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Toxoplasma gondii oxidoreductase, 2OG-Fe(II) oxygenase family protein 0.0215 0.0655 0.4846
Entamoeba histolytica protein kinase, putative 0.0426 0.1389 0.2619
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0037 0.0036 0.0032
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0051 0.0086 0.0163
Brugia malayi RNA binding protein 0.0191 0.0572 0.0816
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.024 0.0741 0.0737
Plasmodium falciparum serine/threonine protein kinase, putative 0.0081 0.0188 0.2352
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0216 0.0659 0.0655
Loa Loa (eye worm) hypothetical protein 0.0076 0.0172 0.0191
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0075 0.0236
Plasmodium vivax vivapain-1 0.0047 0.0071 0.0874
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0241 0.0744 0.1403
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0216 0.0659 0.0657
Trichomonas vaginalis bromodomain-containing protein, putative 0.0026 0.0001 0.0001
Trypanosoma cruzi ATPase, putative 0.0029 0.0008 0.0013
Echinococcus granulosus tyrosine protein kinase Fyn 0.0079 0.0182 0.0178
Onchocerca volvulus 0.0073 0.0161 0.0466
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0032 0.0019 0.0099
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0758 0.2539 1
Brugia malayi TAR-binding protein 0.0191 0.0572 0.0816
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0049 0.0079 0.0087
Echinococcus granulosus insulin receptor 0.0181 0.0537 0.0533
Echinococcus multilocularis tyrosine protein kinase HCK 0.0045 0.0065 0.006
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0195 0.0587 0.1105
Echinococcus multilocularis glutathione S transferase 0.0185 0.0549 0.0545
Loa Loa (eye worm) AUR protein kinase 0.0081 0.0188 0.021
Loa Loa (eye worm) hypothetical protein 0.0181 0.0536 0.06
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.011 0.029 0.3145
Trichomonas vaginalis AGC family protein kinase 0.0197 0.0592 0.1118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0069 0.0129
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.052 0.1715 0.245
Leishmania major hypothetical protein, conserved 0.0215 0.0655 0.7135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0034 0.0027 0.0028
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0057 0.0105 0.1309
Trypanosoma cruzi Heat shock protein 83, putative 0.0047 0.0072 0.0133
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.012 0.0326 0.1232
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0772 0.0771
Echinococcus multilocularis glutathione s transferase mu 0.0054 0.0096 0.0092
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0056 0.0103 0.0099
Toxoplasma gondii aurora kinase 0.0081 0.0188 0.1386
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0074 0.007
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0188 0.0355
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0124 0.0234
Giardia lamblia Cathepsin B precursor 0.007 0.0151 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.07 0.1321
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0116 0.3233
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0158 0.0156
Loa Loa (eye worm) hypothetical protein 0.019 0.0569 0.0637
Loa Loa (eye worm) hypothetical protein 0.0044 0.0061 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0056 0.0105
Echinococcus multilocularis tar DNA binding protein 0.0191 0.0572 0.0568
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0061 0.0122 0.0689
Echinococcus granulosus glutathione s transferase mu 0.0054 0.0096 0.0092
Leishmania major hypothetical protein, unknown function 0.0061 0.0122 0.1314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0291 0.0918 0.1732
Loa Loa (eye worm) hypothetical protein 0.003 0.0014 0.0014
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0241 0.0745 0.4254
Echinococcus granulosus cyclin dependent kinase 0.0072 0.0158 0.0154
Loa Loa (eye worm) STE/STE11/ASK protein kinase 0.0046 0.0069 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Echinococcus multilocularis endoplasmin 0.0044 0.0062 0.0057
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0028 0.0007 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0109 0.0286 0.0281
Echinococcus multilocularis neuroglian 0.0037 0.0036 0.0031
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0092 0.0228 0.0224
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Schistosoma mansoni protein kinase 0.0081 0.0188 0.0187
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0075 0.0167 0.0237
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0081 0.0188 0.2352
Trichomonas vaginalis AGC family protein kinase 0.0426 0.1389 0.262
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.006 0.0116 0.0849
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0079 0.0182 0.0178
Trichomonas vaginalis AGC family protein kinase 0.006 0.0117 0.022
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0051 0.0086 0.0632
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0032 0.0019 0.0033
Echinococcus granulosus nervana 2 0.024 0.0741 0.0737
Plasmodium vivax glutathione S-transferase, putative 0.0239 0.0737 0.9252
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.012 0.0326 0.0322
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0185 0.0551 0.0617
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0116 0.0114
Brugia malayi casein kinase 1, delta 0.0031 0.0016 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.07 0.1321
Plasmodium vivax calcium-dependent protein kinase, putative 0.006 0.0116 0.1442
Loa Loa (eye worm) hypothetical protein 0.0092 0.0228 0.0254
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Echinococcus granulosus cyclin dependent kinase 5 0.0072 0.0158 0.0154
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Echinococcus granulosus cathepsin L cysteine protease 0.0047 0.0071 0.0066
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0073 0.0161 0.2015
Echinococcus multilocularis c src tyrosine kinase 0.0072 0.0159 0.0154
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0031 0.0017 0.0013
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0124 0.1337
Giardia lamblia Heat shock protein HSP 90-alpha 0.0047 0.0072 0.0223
Echinococcus granulosus mitogen activated protein kinase 11 0.0195 0.0587 0.0583
Giardia lamblia Cathepsin B precursor 0.007 0.0151 0.0535
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0072 0.0135
Leishmania major protein kinase, putative 0.006 0.0116 0.1249
Brugia malayi hypothetical protein 0.0051 0.0086 0.0121
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0061 0.0122 0.0117
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0095 0.0237 0.0264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0161 0.0305
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0074 0.0138
Brugia malayi hypothetical protein 0.0085 0.0202 0.0287
Echinococcus granulosus serine:threonine protein kinase 0.0048 0.0075 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0124 0.0234
Giardia lamblia Kinase, CMGC GSK 0.0078 0.018 0.0653
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0082
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Entamoeba histolytica PH domain containing protein kinase, putative 0.0042 0.0056 0.0104
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0079 0.0183 0.0204
Plasmodium vivax casein kinase 1, putative 0.0031 0.0016 0.018
Echinococcus granulosus 5' AMP activated protein kinase subunit beta 1 0.0031 0.0018 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Loa Loa (eye worm) hypothetical protein 0.0081 0.0191 0.0212
Brugia malayi Papain family cysteine protease containing protein 0.0047 0.0071 0.0099
Schistosoma mansoni protein kinase 0.0054 0.0096 0.0094
Loa Loa (eye worm) phosphatidylinositol 3 0.0128 0.0352 0.0394
Trichomonas vaginalis CAMK family protein kinase 0.011 0.029 0.0546
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0079 0.0182 0.0178
Leishmania major protein kinase A catalytic subunit isoform 2 0.0032 0.0019 0.0189
Schistosoma mansoni heat shock protein 0.0047 0.0072 0.007
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0124 0.0234
Echinococcus multilocularis mitogen activated protein kinase 14 0.0195 0.0587 0.0583
Brugia malayi FAT domain containing protein 0.0036 0.0033 0.0045
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.006 0.0117 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0518 0.0517
Echinococcus multilocularis Glutaredoxin protein 5 0.024 0.0741 0.0737
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.053 0.1749 0.33
Echinococcus granulosus cyclin dependent kinase 7 0.0049 0.0079 0.0074
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0075 0.0139
Entamoeba histolytica hypothetical protein 0.0109 0.0286 0.0537
Giardia lamblia Kinase, CMGC CDK 0.0072 0.0158 0.0565
Entamoeba histolytica serine/threonine protein kinase, putative 0.0048 0.0075 0.0139
Schistosoma mansoni protein kinase C 0.0037 0.0038 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0075 0.0073
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0061 0.0122 0.0172
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0128 0.0352 0.2009
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0078 0.018 0.1327
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0078 0.018 0.0176
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0031 0.0016 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.0122 0.023
Entamoeba histolytica protein kinase, putative 0.0028 0.0007 0.001
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Loa Loa (eye worm) hypothetical protein 0.0061 0.0122 0.0135
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0159 0.0157
Onchocerca volvulus 0.0085 0.0202 0.059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0161 0.0305
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0032 0.0019 0.0024
Echinococcus multilocularis 5' AMP activated protein kinase subunit beta 1 0.0031 0.0018 0.0013
Echinococcus multilocularis heat shock protein 90 0.0047 0.0072 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0161 0.0305
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0161 0.0469 0.2679
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0092 0.0228 0.0226
Trichomonas vaginalis bromodomain-containing protein, putative 0.0026 0.0001 0.0001
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Echinococcus granulosus Immunoglobulin 0.003 0.0013 0.0008
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0061 0.0122 0.0892
Echinococcus multilocularis bromodomain containing 2 0.0041 0.0051 0.0047
Loa Loa (eye worm) TK/EGFR protein kinase 0.0245 0.076 0.0852
Echinococcus granulosus cathepsin l1 0.0073 0.0161 0.0157
Onchocerca volvulus 0.0984 0.3324 1
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0037 0.0036 0.0032
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.0072 0.0133
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0124 0.012
Trichomonas vaginalis AGC family protein kinase 0.006 0.0117 0.022
Echinococcus granulosus cathepsin L cysteine proteinase 0.0073 0.0161 0.0157
Echinococcus granulosus tyrosine protein kinase Src42A 0.0079 0.0182 0.0178
Leishmania major farnesyl pyrophosphate synthase 0.0051 0.0086 0.093
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.1354 0.4609 0.6587
Echinococcus multilocularis AMPK beta subunit 0.0058 0.0112 0.0107
Echinococcus multilocularis tyrosine protein kinase shark 0.0041 0.0052 0.0048
Brugia malayi Cathepsin L-like precursor 0.0073 0.0161 0.0229
Echinococcus multilocularis roundabout 2 0.0045 0.0064 0.006
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0249 0.0772 0.0769
Entamoeba histolytica hypothetical protein 0.0061 0.0122 0.0227
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0169 0.0495 0.0491
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0061 0.0122 0.012
Brugia malayi Matrixin family protein 0.0076 0.0172 0.0244
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0016 0.0021
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Echinococcus multilocularis glutathione S transferase 0.0042 0.0053 0.0049
Plasmodium falciparum casein kinase 1 0.0031 0.0016 0.018
Brugia malayi Protein kinase domain containing protein 0.006 0.0117 0.0165
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0046 0.0069 0.0128
Entamoeba histolytica protein kinase, putative 0.0039 0.0044 0.0081
Echinococcus multilocularis tyrosine protein kinase csk 0.0038 0.0041 0.0037
Leishmania major protein kinase, putative 0.0037 0.0039 0.0411
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0047 0.0071 0.0131
Loa Loa (eye worm) hypothetical protein 0.2042 0.6996 0.7851
Echinococcus granulosus casein kinase I alpha 0.0031 0.0016 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0291 0.0918 0.1732
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0079 0.0182 0.0178
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0037 0.0038 0.0034
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0103 0.0267 0.2896
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0186 0.0555 0.0621
Echinococcus multilocularis dual specificity mitogen activated protein 0.0054 0.0096 0.0092
Loa Loa (eye worm) cysteine protease 0.0073 0.0161 0.0179
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0037 0.0036 0.0032
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0256 0.0796 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0161 0.0305
Echinococcus multilocularis basement membrane specific heparan sulfate 0.003 0.0013 0.0008
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0116 0.3233
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0161 0.0229
Echinococcus granulosus tyrosine protein kinase Srms 0.0041 0.0052 0.0048
Entamoeba histolytica cysteine protease, putative 0.0073 0.0161 0.0302
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0097 0.0245 0.1397
Loa Loa (eye worm) TK/EPH protein kinase 0.0054 0.0096 0.0106
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.01 0.0256 0.0252
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.006 0.0116 0.0128
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Loa Loa (eye worm) hypothetical protein 0.0085 0.0202 0.0225
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0215 0.0655 0.0651
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0061 0.0122 0.0172
Brugia malayi Pleckstrin Homology Domain 0.0028 0.0004 0.0004
Echinococcus multilocularis cyclin dependent kinase 5 0.0072 0.0158 0.0154
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0044 0.0062 0.066
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0064 0.0133 0.0128
Trichomonas vaginalis STE family protein kinase 0.0054 0.0096 0.0181
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0185 0.0551 0.0547
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0051 0.0086 0.1477
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0072 0.0158 0.0154
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0074 0.0797
Loa Loa (eye worm) hypothetical protein 0.0215 0.0655 0.0734
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0076 0.0172 0.017
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0072 0.016 0.0178
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0054 0.0096 0.0179
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0037 0.0039 0.0071
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0078 0.018 0.0201
Trichomonas vaginalis CAMK family protein kinase 0.011 0.029 0.0546
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0129
Trypanosoma brucei AAA ATPase, putative 0.0034 0.0026 0.0142
Entamoeba histolytica casein kinase 1, putative 0.0031 0.0016 0.0027
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0124 0.0231
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0074 0.0138
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0072 0.0158 0.171
Trypanosoma cruzi 2OG-Fe(II) oxygenase superfamily, putative 0.0215 0.0655 0.1234
Entamoeba histolytica protein kinase, putative 0.008 0.0187 0.035
Echinococcus granulosus serine threonine protein kinase nrc 0.0256 0.0796 0.0792
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0065 0.0134 0.0189
Entamoeba histolytica PH domain containing protein kinase, putative 0.0267 0.0834 0.1571
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0188 0.0187
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0195 0.0587 0.3351
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0124 0.0908
Echinococcus granulosus ephrin type A receptor 4 A 0.0047 0.0072 0.0068
Entamoeba histolytica protein kinase, putative 0.0031 0.0016 0.0027
Brugia malayi hypothetical protein 0.0031 0.0016 0.0021
Brugia malayi plexin A 0.0053 0.0093 0.0131
Schistosoma mansoni protein kinase 0.0037 0.0039 0.0037
Entamoeba histolytica serine/threonine protein kinase, putative 0.011 0.029 0.0544
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0195 0.0587 0.6387
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Plasmodium falciparum NIMA related kinase 1 0.0057 0.0105 0.1309
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0128 0.0352 0.0351
Trypanosoma brucei heat shock protein, putative 0.0047 0.0072 0.0404
Echinococcus multilocularis serine:threonine protein kinase N2 0.0176 0.0518 0.0514
Schistosoma mansoni endoplasmin 0.0047 0.0072 0.007
Echinococcus granulosus mitogen activated protein kinase 14 0.0195 0.0587 0.0583
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0036 0.0035 0.0033
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0042 0.0056 0.0686
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0061 0.0122 0.1515
Leishmania major casein kinase, putative 0.0031 0.0016 0.0156
Loa Loa (eye worm) IKK protein kinase 0.0384 0.124 0.1391
Onchocerca volvulus 0.0073 0.0161 0.0466
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0291 0.0918 0.0914
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0291 0.0918 0.173
Loa Loa (eye worm) hypothetical protein 0.0051 0.0086 0.0095
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0182 0.054 0.0536
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.006 0.0116 0.0111
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.0071 0.0131
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0078 0.018 0.0201
Echinococcus granulosus activin receptor type 0.0037 0.0039 0.0035
Mycobacterium ulcerans hydrolase 0.0092 0.0229 1
Echinococcus multilocularis PAK box P21 Rho binding 0.0028 0.0007 0.0002
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0072 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0192 0.0575 0.1086
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0074 0.007
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0415 0.1351 0.1515
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Brugia malayi Protein kinase domain containing protein 0.008 0.0185 0.0262
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0031 0.0015 0.0015
Onchocerca volvulus 0.0107 0.0282 0.083
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0239 0.0737 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0077 0.0075
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1553 0.53 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0072 0.0158 0.0176
Onchocerca volvulus 0.0041 0.0052 0.0137
Schistosoma mansoni tyrosine kinase 0.0141 0.0399 0.0397
Echinococcus granulosus tyrosine protein kinase Lyn 0.0095 0.0237 0.0233
Giardia lamblia Kinase, AGC PKA 0.0032 0.0019 0.0012
Echinococcus multilocularis cysteine protease 0.0073 0.0161 0.0157
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0031 0.0016 0.0016
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0072 0.0159 0.0155
Leishmania major phosphatidylinositol 3-kinase, putative 0.0128 0.0352 0.3829
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.07 0.1321
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0061 0.0122 0.0892
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0291 0.0918 0.0917
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0069 0.0129
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.006 0.0117 0.0129
Brugia malayi Cathepsin L-like precursor 0.0046 0.0069 0.0096
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0469 0.1536 0.2896
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Echinococcus granulosus cysteine protease 0.0047 0.0071 0.0066
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0216 0.0659 0.8272
Loa Loa (eye worm) hypothetical protein 0.0047 0.0072 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.006 0.0116 0.0111
Echinococcus multilocularis mitogen activated protein kinase 14 0.0195 0.0587 0.0583
Brugia malayi Protein kinase domain containing protein 0.0079 0.0181 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0048 0.0046
Echinococcus multilocularis growth factor receptor bound protein 2 0.0034 0.0027 0.0022
Echinococcus granulosus prostaglandin H2 D isomerase 0.0239 0.0737 0.0733
Echinococcus multilocularis cathepsin b 0.0181 0.0536 0.0532
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Echinococcus granulosus cpg binding protein 0.003 0.0012 0.0008
Schistosoma mansoni protein kinase subunit beta 0.0031 0.0018 0.0016
Giardia lamblia GTOR 0.0291 0.0918 0.3577
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0061 0.0122 0.0117
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0216 0.0659 0.1241
Trichomonas vaginalis CMGC family protein kinase 0.0072 0.0158 0.0298
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0061 0.0122 0.012
Echinococcus granulosus nervana 2 0.024 0.0741 0.0737
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0037 0.0038 0.0071
Brugia malayi Matrixin family protein 0.0076 0.0172 0.0244
Brugia malayi intracellular kinase 0.0078 0.018 0.0256
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0075 0.0073
Loa Loa (eye worm) hypothetical protein 0.1012 0.342 0.3837
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0073 0.0161 0.2015
Brugia malayi Protein kinase domain containing protein 0.0176 0.0518 0.0739
Plasmodium falciparum protein kinase, putative 0.0037 0.0039 0.0474
Echinococcus granulosus cathepsin b 0.0181 0.0536 0.0532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Echinococcus multilocularis serine:threonine protein kinase 0.0048 0.0075 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.0072 0.0158 0.0298
Loa Loa (eye worm) hypothetical protein 0.0076 0.0172 0.0191
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0213 0.0647 0.0725
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0073 0.0161 0.0305
Brugia malayi Protein kinase domain containing protein 0.0426 0.1389 0.1983
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0032 0.0019 0.0099
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0267 0.0834 0.1571
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0072 0.0158 0.0176
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0185 0.0551 0.0547
Schistosoma mansoni protein kinase subunit gamma 0.012 0.0326 0.0325
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0048 0.0075 0.0806
Leishmania major casein kinase II, putative 0.0042 0.0056 0.0595
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0065 0.0134 0.0148
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0051 0.0086 0.1072
Brugia malayi cell division control protein 2 homolog 0.0072 0.0158 0.0224
Schistosoma mansoni kinase 0.0117 0.0315 0.0313
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0195 0.0587 0.1105
Trichomonas vaginalis CAMK family protein kinase 0.011 0.029 0.0546
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0109 0.0289 0.0285
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0054 0.0096 0.0106
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.0058 0.0112 0.0208
Onchocerca volvulus Cathepsin L homolog 0.0073 0.0161 0.0466
Entamoeba histolytica cell division protein kinase 2, putative 0.0072 0.0158 0.0296
Schistosoma mansoni tyrosine kinase 0.0181 0.0537 0.0535
Trichomonas vaginalis AGC family protein kinase 0.0186 0.0555 0.1047
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0518 0.0978
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0216 0.0659 0.0655
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Loa Loa (eye worm) hypothetical protein 0.0046 0.0069 0.0075
Onchocerca volvulus 0.0049 0.0079 0.0217
Loa Loa (eye worm) hypothetical protein 0.0085 0.0202 0.0225
Echinococcus multilocularis heat shock protein 0.0047 0.0072 0.0067
Giardia lamblia Kinase, AGC AKT 0.0092 0.0229 0.0846
Brugia malayi Protein kinase domain containing protein 0.0186 0.0555 0.0791
Brugia malayi Cathepsin L-like precursor 0.0073 0.0161 0.0229
Trichomonas vaginalis CK1 family protein kinase 0.0031 0.0016 0.0029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0079 0.0182 0.0178
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.1553 0.53 1
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0572 0.0571
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.07 0.1321
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0526 0.0993
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0216 0.0659 0.1243
Schistosoma mansoni protein kinase 0.0037 0.0036 0.0035
Entamoeba histolytica p21-activated kinase 0.0048 0.0074 0.0138
Loa Loa (eye worm) hypothetical protein 0.0053 0.0093 0.0103
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0074 0.0919
Entamoeba histolytica cysteine protease, putative 0.0047 0.0071 0.0131
Echinococcus multilocularis protein tyrosine kinase 0.0166 0.0484 0.048
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0041 0.0051 0.005
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0056 0.0105
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0256 0.0796 0.0792
Loa Loa (eye worm) AUR protein kinase 0.0081 0.0188 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.1074 0.1072
Schistosoma mansoni protein kinase 0.006 0.0116 0.0114
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0072 0.0158 0.171
Echinococcus granulosus rho-associated protein kinase 1 0.0336 0.1074 0.107
Echinococcus granulosus cathepsin l cysteine peptidase 0.0073 0.0161 0.0157
Trypanosoma brucei heat shock protein, putative 0.0047 0.0072 0.0404
Loa Loa (eye worm) hypothetical protein 0.0097 0.0246 0.0275
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0037 0.0038 0.0033
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.024 0.0741 0.0737
Mycobacterium leprae PROBABLE HYDROLASE 0.0092 0.0229 1
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0072 0.0133
Brugia malayi Protein kinase domain containing protein 0.0048 0.0075 0.0105
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Echinococcus multilocularis tyrosine protein kinase csk 0.0038 0.0041 0.0037
Echinococcus multilocularis casein kinase I alpha 0.0031 0.0016 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.018 0.034
Brugia malayi Protein kinase domain containing protein 0.0041 0.0052 0.0072
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0027 0.0051
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0161 0.0302
Entamoeba histolytica protein kinase, putative 0.0036 0.0035 0.0063
Echinococcus granulosus plexin a4 0.0053 0.0093 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0038 0.004 0.0075
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0116 0.0112
Leishmania major phosphatidylinositol kinase, putative 0.0061 0.0122 0.1314
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0078 0.018 0.1954
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0551 0.055
Brugia malayi Tyrosine-protein kinase abl-1 0.0051 0.0085 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0074 0.0073
Toxoplasma gondii casein kinase I 0.0031 0.0016 0.0106
Trypanosoma cruzi cysteine protease, putative 0.0047 0.0071 0.0131
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.006 0.0116 0.0849
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0161 0.0305
Loa Loa (eye worm) ctsf protein 0.0073 0.0161 0.0179
Giardia lamblia Kinase, CMGC CK2 0.0042 0.0056 0.016
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0061 0.0122 0.0227
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Onchocerca volvulus Matrilysin homolog 0.0076 0.0172 0.0498
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0188 0.0355
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0036 0.0035 0.0063
Onchocerca volvulus 0.0031 0.0016 0.0027
Trypanosoma brucei heat shock protein, putative 0.0047 0.0072 0.0404
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Brugia malayi Protein kinase domain containing protein 0.0041 0.0052 0.0072
Trichomonas vaginalis STE family protein kinase 0.0037 0.0036 0.0069
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0079 0.0182 0.0178
Entamoeba histolytica protein kinase rad3, putative 0.0092 0.0228 0.0428
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0037 0.0036 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0191 0.057 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1553 0.53 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0698 0.233 0.4395
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0037 0.0036 0.0032
Schistosoma mansoni serine/threonine-protein kinase 0.0267 0.0834 0.0832
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0116 0.1251
Loa Loa (eye worm) TK/FER protein kinase 0.0041 0.0052 0.0057
Entamoeba histolytica heat shock protein 90, putative 0.0047 0.0072 0.0133
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.006 0.0116 0.0111
Plasmodium falciparum calcium-dependent protein kinase 4 0.006 0.0116 0.1442
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0124 0.012
Loa Loa (eye worm) TK/INSR protein kinase 0.0181 0.0537 0.0601
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0068 0.0144 0.0159
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0181 0.0536 0.0535
Loa Loa (eye worm) phosphatidylinositol kinase 0.0061 0.0122 0.0135
Trichomonas vaginalis CMGC family protein kinase 0.0072 0.0158 0.0298
Schistosoma mansoni protein kinase 0.0116 0.0313 0.0311
Brugia malayi Matrixin family protein 0.0076 0.0172 0.0244
Trypanosoma brucei polo-like protein kinase 0.011 0.029 0.165
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0216 0.0659 0.7173
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0161 0.0305
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Schistosoma mansoni tyrosine kinase 0.0079 0.0182 0.0181
Trypanosoma cruzi cysteine proteinase, putative 0.0047 0.0071 0.0131
Trichomonas vaginalis AGC family protein kinase 0.0426 0.1389 0.262
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Brugia malayi Matrixin family protein 0.0076 0.0172 0.0244
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0252 0.0784 0.0878
Brugia malayi Fibronectin type III domain containing protein 0.0031 0.0016 0.0021
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0116 0.0313 0.0309
Entamoeba histolytica hypothetical protein 0.0097 0.0245 0.0461
Trichomonas vaginalis STE family protein kinase 0.0054 0.0096 0.0181
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0099 0.0252 0.0248
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.006 0.0116 0.0111
Loa Loa (eye worm) hypothetical protein 0.0032 0.0021 0.0022
Brugia malayi Furin-like cysteine rich region family protein 0.0245 0.076 0.1085
Echinococcus granulosus tyrosine kinase 0.0064 0.0133 0.0128
Echinococcus multilocularis NCK adaptor protein 0.0034 0.0027 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.0016
Schistosoma mansoni tyrosine kinase 0.0166 0.0484 0.0483
Brugia malayi Immunoglobulin I-set domain containing protein 0.0251 0.078 0.1113
Trichomonas vaginalis AGC family protein kinase 0.0426 0.1389 0.262
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0161 0.0305
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0061 0.0122 0.1515
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0072 0.0158 0.0176
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.006 0.0116 0.0849
Echinococcus multilocularis tyrosine protein kinase Abl 0.0087 0.0211 0.0207
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0216 0.0659 0.8272
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0048 0.0075 0.0806
Trichomonas vaginalis PIKK family atypical protein kinase 0.0191 0.057 0.1076
Schistosoma mansoni fkbp-rapamycin associated protein 0.0092 0.0228 0.0226
Leishmania major cathepsin L-like protease 0.0073 0.0161 0.1747
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0046 0.0069 0.0127
Loa Loa (eye worm) phosphatidylinositol 3 0.0061 0.0122 0.0135
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0038 0.004 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0216 0.0659 0.1241
Toxoplasma gondii CMGC kinase, CK2 family 0.0042 0.0056 0.0404
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0071 0.0133
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0128
Brugia malayi Protein kinase domain containing protein 0.0089 0.0217 0.0308
Brugia malayi Cathepsin L-like precursor 0.0073 0.0161 0.0229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0071 0.0133
Trichomonas vaginalis bromodomain containing protein, putative 0.0026 0.0001 0.0001
Echinococcus granulosus serine protein kinase ATM 0.0092 0.0228 0.0224
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0042 0.0056 0.0061
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0124 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0016 0.0014
Trypanosoma brucei aurora B kinase 0.0081 0.0188 0.107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Brugia malayi Papain family cysteine protease containing protein 0.0047 0.0071 0.0099
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0032 0.0019 0.0218
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0181 0.0536 0.0535
Echinococcus multilocularis calcium dependent protein kinase 0.0044 0.0061 0.0057
Giardia lamblia Kinase, CAMK CAMKL 0.0048 0.0075 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0015 0.0028
Giardia lamblia Kinase, AGC PKA 0.0256 0.0796 0.3094
Schistosoma mansoni tyrosine kinase 0.0181 0.0537 0.0535
Brugia malayi Protein kinase domain containing protein 0.0097 0.0245 0.0349
Echinococcus granulosus protein kinase C gamma type 0.0232 0.0715 0.0711
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0074 0.007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0181 0.0536 0.0535
Trypanosoma brucei Heat shock protein 83, putative 0.0047 0.0072 0.0404
Schistosoma mansoni cpg binding protein 0.003 0.0012 0.0011
Brugia malayi STE20-like kinase MST 0.0104 0.0271 0.0385
Trichomonas vaginalis STE family protein kinase 0.0028 0.0007 0.0012
Echinococcus multilocularis intersectin 2 0.0035 0.003 0.0025
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0032 0.0019 0.0033
Schistosoma mansoni serine/threonine-protein kinase 0.0267 0.0834 0.0832
Schistosoma mansoni cathepsin F (C01 family) 0.0073 0.0161 0.016
Loa Loa (eye worm) phosphatidylinositol 3 0.0469 0.1536 0.1722
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0128 0.0352 0.2009
Entamoeba histolytica PH domain containing protein kinase, putative 0.0267 0.0834 0.1571
Echinococcus granulosus tyrosine protein kinase shark 0.0041 0.0052 0.0048
Plasmodium vivax endoplasmin, putative 0.0047 0.0072 0.0887
Schistosoma mansoni nck2/grb4 0.0034 0.0027 0.0025
Leishmania major cysteine peptidase A (CPA) 0.0073 0.0161 0.1747
Trichomonas vaginalis PIKK family atypical protein kinase 0.0178 0.0526 0.0992
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0048 0.0046
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0169 0.0495 0.0491
Trichomonas vaginalis AGC family protein kinase 0.006 0.0117 0.022
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0013
Schistosoma mansoni tyrosine kinase 0.0036 0.0032 0.0031
Trichomonas vaginalis STE family protein kinase 0.0036 0.0035 0.0065
Loa Loa (eye worm) fibroinase 0.0073 0.0161 0.0179
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0216 0.0659 0.0738
Giardia lamblia Kinase, STE STE20 0.0037 0.0036 0.0083
Brugia malayi protein-tyrosine kinase 0.0064 0.0133 0.0187
Echinococcus granulosus tyrosine protein kinase Blk 0.0064 0.0133 0.0128
Leishmania major protein kinase A catalytic subunit isoform 1 0.0032 0.0019 0.0189
Loa Loa (eye worm) hypothetical protein 0.0049 0.0079 0.0087
Entamoeba histolytica protein kinase domain containing protein 0.0078 0.018 0.0338
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0038 0.0071
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0124 0.012
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Onchocerca volvulus 0.0192 0.0576 0.1716
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0291 0.0918 0.131
Schistosoma mansoni growth factor receptor-bound protein 0.0034 0.0027 0.0025
Leishmania major hypothetical protein, unknown function 0.0215 0.0655 0.7135
Brugia malayi MH2 domain containing protein 0.0354 0.1138 0.1625
Brugia malayi Protein kinase domain containing protein 0.0181 0.0537 0.0765
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Brugia malayi serine/threonine kinase 12 0.0081 0.0188 0.0267
Trichomonas vaginalis AGC family protein kinase 0.0426 0.1389 0.262
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.0142
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0074 0.0418
Trypanosoma brucei heat shock protein 90, putative 0.0047 0.0072 0.0404
Loa Loa (eye worm) AUR protein kinase 0.0081 0.0188 0.021
Loa Loa (eye worm) hypothetical protein 0.0081 0.0191 0.0212
Echinococcus granulosus geminin 0.0344 0.1102 0.1098
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0291 0.0918 0.173
Schistosoma mansoni hypothetical protein 0.0402 0.1304 0.1303
Onchocerca volvulus 0.0041 0.0052 0.0137
Echinococcus granulosus NDR protein kinase 0.0176 0.0518 0.0514
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0061 0.0122 0.0689
Trichomonas vaginalis PIKK family atypical protein kinase 0.0128 0.0352 0.0665
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Echinococcus granulosus neuroglian 0.0037 0.0036 0.0031
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Trypanosoma cruzi cruzipain precursor, putative 0.0027 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0036 0.0033 0.0032
Trypanosoma brucei casein kinase I, isoform 2 0.0031 0.0016 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0192 0.0575 0.1086
Echinococcus multilocularis neuropeptide receptor A26 0.0462 0.1512 0.1509
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0061 0.0122 0.1515
Echinococcus granulosus c-Jun N-terminal kinases 0.0345 0.1106 0.1102
Schistosoma mansoni protein kinase 0.006 0.0116 0.0114
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0252 0.0782 0.0876
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0051 0.0086 0.0163
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0038 0.004 0.0073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0161 0.0305
Schistosoma mansoni cathepsin F (C01 family) 0.0073 0.0161 0.016
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0032 0.0019 0.0014
Loa Loa (eye worm) hypothetical protein 0.0076 0.0172 0.0191
Schistosoma mansoni endoplasmin 0.0047 0.0072 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0161 0.0917
Brugia malayi Protein kinase domain containing protein 0.0072 0.0158 0.0224
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0073 0.0161 0.0157
Schistosoma mansoni cpg binding protein 0.003 0.0012 0.0011
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0046 0.0069 0.0128
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0061 0.0122 0.1515
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0074 0.0541
Echinococcus granulosus epidermal growth factor receptor 0.0245 0.076 0.0756
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0086 0.063
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0061 0.0122 0.0117
Brugia malayi p70 ribosomal S6 kinase beta 0.0415 0.1351 0.1929
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0038 0.004 0.0075
Brugia malayi Variant SH3 domain containing protein 0.0034 0.0027 0.0036
Loa Loa (eye worm) matrixin family protein 0.0168 0.0492 0.0551
Echinococcus granulosus tyrosine protein kinase Src42A 0.0043 0.0057 0.0053
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0079 0.0183 0.0259
Leishmania major heat shock protein 83-1 0.0047 0.0072 0.0769
Brugia malayi ephrin receptor 1 precursor 0.0034 0.0026 0.0034
Leishmania major protein kinase, putative 0.0081 0.0188 0.204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0228 0.043
Brugia malayi Variant SH3 domain containing protein 0.0034 0.0027 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0291 0.0918 0.1732
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.006 0.0116 0.0163

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.019 nM Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMC ChEMBL. 15896958
Ki (binding) = 0.019 nM Inhibition constant against human cathepsin K in fluorescence assay using Cbz-Phe-Arg-AMC ChEMBL. 15896958
Ki (binding) = 0.46 nM Inhibition constant against human cathepsin H using L-Arg-b-naphthalamide ChEMBL. 15896958
Ki (binding) = 0.46 nM Inhibition constant against human cathepsin H using L-Arg-b-naphthalamide ChEMBL. 15896958
Ki (binding) = 0.79 nM Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMC ChEMBL. 15896958
Ki (binding) = 0.79 nM Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMC ChEMBL. 15896958
Ki (binding) = 1.3 nM Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMC ChEMBL. 15896958
Ki (binding) = 1.3 nM Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMC ChEMBL. 15896958

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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