Detailed information for compound 343354

Basic information

Technical information
  • TDR Targets ID: 343354
  • Name: N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin -6-yl]-2-thiophen-2-ylquinoline-4-carboxamide
  • MW: 507.649 | Formula: C30H29N5OS
  • H donors: 1 H acceptors: 3 LogP: 5.67 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCN1CCN(CC1)c1cc(C)c2c(n1)ccc(c2)NC(=O)c1cc(nc2c1cccc2)c1cccs1
  • InChi: 1S/C30H29N5OS/c1-3-34-12-14-35(15-13-34)29-17-20(2)23-18-21(10-11-26(23)33-29)31-30(36)24-19-27(28-9-6-16-37-28)32-25-8-5-4-7-22(24)25/h4-11,16-19H,3,12-15H2,1-2H3,(H,31,36)
  • InChiKey: MPLFGSSKQRHUCS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[2-(4-ethylpiperazin-1-yl)-4-methyl-6-quinolyl]-2-(2-thienyl)quinoline-4-carboxamide
  • N-[2-(4-ethyl-1-piperazinyl)-4-methyl-6-quinolyl]-2-(2-thienyl)-4-quinolinecarboxamide
  • N-[2-(4-ethylpiperazin-1-yl)-4-methyl-quinolin-6-yl]-2-thiophen-2-yl-quinoline-4-carboxamide
  • N-[2-(4-ethylpiperazino)-4-methyl-6-quinolyl]-2-(2-thienyl)cinchoninamide
  • N-[2-(4-ethylpiperazin-1-yl)-4-methyl-6-quinolyl]-2-(2-thienyl)cinchoninamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0144 0.0416 0.2741
Schistosoma mansoni cpg binding protein 0.0099 0.027 0.027
Schistosoma mansoni histone deacetylase 4 5 0.0038 0.0073 0.0073
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.007 0.0176 0.1092
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.002 0.0012 0.0041
Brugia malayi intermediate filament protein 0.0025 0.0029 0.0029
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0586 0.1844 0.1844
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.007 0.0176 0.0595
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0034 0.0058 0.0058
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Leishmania major histone deacetylase, putative 0.0038 0.0073 0.0163
Brugia malayi nuclear receptor NHR-88 0.0021 0.0016 0.0016
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0135 0.0385 0.1291
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0023 0.0023
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0169 0.0495 0.0495
Schistosoma mansoni hypothetical protein 0.0027 0.0035 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.2952 1
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0135 0.0385 0.1291
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0082 0.0213 0.0213
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0012
Trypanosoma brucei heat shock protein, putative 0.007 0.0176 0.0435
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0023 0.0023 0.0023
Echinococcus granulosus fmrfamide receptor 0.0023 0.0023 0.0023
Brugia malayi AKH receptor 0.0023 0.0023 0.0023
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0044 0.009 0.0284
Schistosoma mansoni pyruvate dehydrogenase 0.1265 0.4041 0.4041
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0076 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0315
Echinococcus granulosus histone deacetylase 6 0.0038 0.0073 0.0073
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0501 0.157 0.3886
Brugia malayi Bromodomain containing protein 0.0232 0.0699 0.0699
Echinococcus granulosus DNA topoisomerase 2 alpha 0.007 0.0176 0.0176
Schistosoma mansoni aldehyde dehydrogenase 0.0039 0.0073 0.0073
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0037 0.0067 0.0166
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0058 0.0135 0.0335
Leishmania major trypanothione reductase 0.0167 0.0488 0.1193
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.2952 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0381 0.118 0.4006
Brugia malayi Endoplasmin precursor 0.007 0.0176 0.0176
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0019 0.0011 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0048 0.0102 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0011 0.0026
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0102 0.0102
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0426 0.1326 0.1326
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0047 0.01 0.01
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0023 0.0023 0.0023
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0016 0.0016
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0039 0.0075 0.0075
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0058 0.0135 0.0726
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0048 0.0102 0.0102
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0019 0.0011 0.0011
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0041 0.0079 0.0079
Mycobacterium tuberculosis Probable oxidoreductase 0.0423 0.1317 0.4475
Loa Loa (eye worm) hypothetical protein 0.0044 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0227 0.0682 0.0682
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0016 0.0016
Trypanosoma brucei AAA ATPase, putative 0.002 0.0012 0.003
Schistosoma mansoni myelin transcription factor 1 myt1 0.0095 0.0255 0.0255
Schistosoma mansoni amine GPCR 0.0023 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0048 0.0102 0.0102
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0039 0.0073 0.0073
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0102 0.0102
Brugia malayi acetyltransferase, GNAT family protein 0.0249 0.0753 0.0753
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0031
Onchocerca volvulus Protein ultraspiracle homolog 0.0048 0.0102 0.0674
Trypanosoma cruzi histone deacetylase, putative 0.0038 0.0073 0.018
Entamoeba histolytica acyl-CoA synthetase, putative 0.0044 0.0091 0.0287
Mycobacterium tuberculosis Probable hydrolase 0.0144 0.0416 0.1397
Echinococcus multilocularis glutamate receptor 2 0.0029 0.0041 0.0041
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0048 0.0102 0.0102
Echinococcus granulosus fatty acid amide hydrolase 1 0.3106 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0102 0.0346
Schistosoma mansoni cytochrome P450 0.0135 0.0385 0.0385
Schistosoma mansoni hypothetical protein 0.0021 0.0015 0.0015
Brugia malayi Glutamate receptor 1 precursor 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.0079 0.0079
Onchocerca volvulus Bile acid receptor homolog 0.0111 0.0307 0.2024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0223 0.0669 0.0669
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0083 0.0217 0.0931
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.007 0.0176 0.1159
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0016 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0124 0.035 0.0867
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0074 0.0189 0.064
Loa Loa (eye worm) hypothetical protein 0.0095 0.0255 0.0255
Trypanosoma cruzi hypothetical protein, conserved 0.0144 0.0416 0.1029
Onchocerca volvulus 0.0025 0.0029 0.0191
Schistosoma mansoni glutamate receptor AMPA 0.0029 0.0041 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0191
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0058 0.0135 0.1114
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0079 0.0269
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0212 0.0635 0.0635
Plasmodium falciparum bromodomain protein, putative 0.002 0.0012 0.0103
Echinococcus granulosus glutamate NMDA receptor subunit 0.0107 0.0295 0.0295
Plasmodium vivax histone deacetylase 2, putative 0.0038 0.0073 0.0625
Loa Loa (eye worm) DR-78 0.0021 0.0016 0.0016
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0023 0.0023 0.0023
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0023 0.0023 0.0023
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0046 0.0097 0.0097
Loa Loa (eye worm) PHD-finger family protein 0.0122 0.0343 0.0343
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0091 0.0484
Brugia malayi Bromodomain containing protein 0.002 0.0012 0.0012
Onchocerca volvulus 0.0128 0.0362 0.2387
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0035
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0135 0.0385 0.2165
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Plasmodium vivax conserved Plasmodium protein, unknown function 0.002 0.0012 0.0103
Plasmodium vivax thioredoxin reductase, putative 0.0167 0.0488 0.4206
Echinococcus granulosus g protein coupled receptor 0.0023 0.0023 0.0023
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0128 0.0362 0.1206
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0231 0.0694 0.0694
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0586 0.1844 0.1844
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Brugia malayi SET domain containing protein 0.002 0.0013 0.0013
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0375 0.1161 0.394
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0023 0.0023
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.007 0.0176 0.1514
Brugia malayi polybromodomain protein 0.002 0.0012 0.0012
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0019 0.0011 0.001
Brugia malayi hypothetical protein 0.0021 0.0016 0.0016
Mycobacterium ulcerans aldehyde dehydrogenase 0.0039 0.0073 0.0379
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0049 0.0145
Trypanosoma brucei histone deacetylase, putative 0.0038 0.0073 0.018
Onchocerca volvulus 0.0295 0.0903 0.5953
Onchocerca volvulus 0.0295 0.0903 0.5953
Plasmodium vivax bromodomain protein, putative 0.002 0.0012 0.0103
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0012
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0149 0.043 0.1064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0023 0.0023
Echinococcus multilocularis dro:myosuppressin receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0144 0.0416 0.0416
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0022 0.002 0.0033
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0019 0.0011 0.0011
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0019 0.0011 0.0011
Brugia malayi Kringle domain containing protein 0.004 0.0078 0.0078
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus granulosus global transcription activator snf2l2 0.002 0.0012 0.0012
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0011 0.001
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Leishmania major hypothetical protein, conserved 0.0046 0.0097 0.0224
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0023 0.0023 0.0023
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.0097 0.0835
Loa Loa (eye worm) TOPoisomerase family member 0.007 0.0176 0.0176
Schistosoma mansoni biogenic amine receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0031
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Echinococcus granulosus neuropeptide receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0008 0.0026
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0023 0.0023 0.0023
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0083 0.0218 0.1436
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0059 0.0139 0.0344
Onchocerca volvulus 0.0023 0.0023 0.0152
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0128 0.0362 0.1554
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0019 0.0011 0.0036
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0074 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0249 0.0753 0.0753
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.007 0.0176 0.0968
Loa Loa (eye worm) hypothetical protein 0.0126 0.0355 0.0355
Schistosoma mansoni hypothetical protein 0.009 0.0241 0.0241
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0044 0.009 0.0306
Echinococcus granulosus glutamate receptor 2 0.0034 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0102
Leishmania major cytochrome p450-like protein 0.0135 0.0385 0.0937
Echinococcus granulosus fetal alzheimer antigen falz 0.0138 0.0395 0.0395
Loa Loa (eye worm) histone deacetylase 7A 0.0038 0.0073 0.0073
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0035 0.0035
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0019 0.0011 0.0036
Schistosoma mansoni alpha-glucosidase 0.0157 0.0458 0.0458
Trypanosoma cruzi ISWI complex protein 0.009 0.0241 0.0596
Schistosoma mansoni transcription initiation factor tfiid 0.002 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0102 0.0102
Trypanosoma brucei Bromodomain, putative 0.002 0.0012 0.003
Brugia malayi mbt repeat family protein 0.0083 0.0218 0.0218
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0512 0.1607 0.6898
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0231 0.0694 0.0694
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.0016 0.0016
Echinococcus multilocularis thioredoxin glutathione reductase 0.0169 0.0495 0.0495
Leishmania major histone deacetylase, putative 0.0038 0.0073 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.2952 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0048 0.0102 0.0102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.2952 1
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0078 0.0194
Echinococcus multilocularis g-protein coupled receptor 0.0023 0.0023 0.0023
Mycobacterium tuberculosis Conserved protein 0.0144 0.0416 0.1397
Schistosoma mansoni methyl-cpg binding protein mbd 0.0101 0.0274 0.0274
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0023 0.0024 0.0024
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0176 0.0435
Echinococcus multilocularis sex peptide receptor 0.0023 0.0023 0.0023
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0016 0.0104
Loa Loa (eye worm) phosphatidylinositol 3 0.0059 0.0139 0.0139
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0363 0.1124 0.1124
Brugia malayi Probable DNA topoisomerase II 0.007 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.1313 0.4198 0.4198
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0169 0.0495 0.0495
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0062 0.0148 0.048
Leishmania major cytochrome p450-like protein 0.0135 0.0385 0.0937
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0031
Trypanosoma brucei PAB1-binding protein , putative 0.0046 0.0097 0.024
Mycobacterium ulcerans hypothetical protein 0.0558 0.1753 1
Schistosoma mansoni hypothetical protein 0.0403 0.1253 0.1253
Schistosoma mansoni steroid hormone receptor ad4bp 0.0048 0.0102 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0016 0.0016
Mycobacterium ulcerans putative regultory protein 0.007 0.0176 0.0968
Trypanosoma cruzi trypanothione reductase, putative 0.0167 0.0488 0.1208
Echinococcus granulosus serotonin receptor 0.0023 0.0023 0.0023
Giardia lamblia Pms1-like protein 0.007 0.0176 0.0574
Schistosoma mansoni hypothetical protein 0.0403 0.1253 0.1253
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.007 0.0176 0.0578
Echinococcus multilocularis CREB binding protein 0.002 0.0012 0.0012
Chlamydia trachomatis DNA gyrase subunit B 0.007 0.0176 0.1092
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0138 0.0395 0.0395
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Brugia malayi hypothetical protein 0.0446 0.1391 0.1391
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0023 0.0023
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0295 0.0903 0.0903
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0179 0.0528 0.0528
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Schistosoma mansoni adenoreceptor 0.0023 0.0023 0.0023
Giardia lamblia DNA polymerase alpha subunit A 0.002 0.0012 0.0019
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0151 0.0151
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0062 0.015 0.015
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0041 0.0079 0.0341
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0102 0.0102
Mycobacterium tuberculosis Probable esterase LipL 0.0144 0.0416 0.1397
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0045 0.0095 0.0095
Echinococcus multilocularis dnaJ subfamily B 0.1187 0.3791 0.3791
Echinococcus multilocularis histone deacetylase 7 0.0038 0.0073 0.0073
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0015 0.005
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0135 0.0385 0.1291
Echinococcus granulosus dnaJ subfamily B 0.1187 0.3791 0.3791
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0062 0.015 0.015
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Echinococcus multilocularis Zinc finger, PHD finger 0.0019 0.0011 0.0011
Mycobacterium leprae Probable two component sensor kinase MprB 0.007 0.0176 0.0639
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0039 0.0039
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0023 0.0023
Trypanosoma brucei Bromodomain factor 1 0.002 0.0012 0.003
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0074 0.0189 0.0189
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Chlamydia trachomatis DNA gyrase subunit B 0.007 0.0176 0.1092
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.007 0.0176 0.0639
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0016 0.0016
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.007 0.0176 0.0176
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0058 0.0135 0.1165
Mycobacterium leprae Probable lipase LipE 0.0144 0.0416 0.245
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0135 0.0385 0.2165
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0058 0.0135 0.0135
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0023 0.0023
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0295 0.0903 0.0903
Trichomonas vaginalis STE family protein kinase 0.0044 0.0092 0.031
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.002 0.0012 0.0012
Trichomonas vaginalis esterase, putative 0.0144 0.0416 0.1408
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0058 0.0135 0.1165
Loa Loa (eye worm) hypothetical protein 0.1313 0.4198 0.4198
Loa Loa (eye worm) cytochrome P450 family protein 0.0278 0.0849 0.0849
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0023 0.0023 0.0023
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Loa Loa (eye worm) hypothetical protein 0.0047 0.01 0.01
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0022 0.0022
Schistosoma mansoni amine GPCR 0.0023 0.0023 0.0023
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0135 0.0385 0.1291
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Brugia malayi Calcitonin receptor-like protein seb-1 0.0039 0.0075 0.0075
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0031
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0044 0.0092 0.0227
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.007 0.0176 0.0578
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0023 0.0023 0.0023
Trypanosoma cruzi DNA topoisomerase II, putative 0.007 0.0176 0.0435
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0016 0.0016
Brugia malayi TAZ zinc finger family protein 0.002 0.0012 0.0012
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0059 0.0139 0.0344
Trichomonas vaginalis bromodomain containing protein, putative 0.002 0.0012 0.0041
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0048 0.0102 0.0102
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.007 0.0176 0.0435
Schistosoma mansoni fatty-acid amide hydrolase 0.0375 0.1161 0.1161
Plasmodium vivax SET domain containing protein 0.0024 0.0025 0.0216
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0019 0.0011 0.0045
Echinococcus granulosus cpg binding protein 0.0099 0.027 0.027
Mycobacterium ulcerans beta-lactamase 0.0144 0.0416 0.2342
Schistosoma mansoni neuropeptide receptor 0.0023 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0067 0.0226
Brugia malayi Amidase family protein 0.0375 0.1161 0.1161
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0083 0.0217 0.1869
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0059 0.0139 0.0449
Onchocerca volvulus DNA topoisomerase 2 homolog 0.007 0.0176 0.1159
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0124 0.035 0.1186
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0079 0.0269
Brugia malayi Glutamate receptor 2 precursor 0.0029 0.0041 0.0041
Echinococcus multilocularis sodium channel protein 0.0025 0.0029 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0163 0.0477 0.0477
Brugia malayi BRM protein 0.002 0.0012 0.0012
Toxoplasma gondii LsmAD domain-containing protein 0.0046 0.0097 0.0416
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0102 0.0102
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0074 0.0189 0.0189
Brugia malayi Glycosyl hydrolases family 31 protein 0.0183 0.054 0.054
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0355 0.1204
Plasmodium falciparum glutathione reductase 0.0167 0.0488 0.4206
Brugia malayi nuclear receptor NHR-67 0.0021 0.0016 0.0016
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0059 0.0139 0.0328
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.007 0.0176 0.0968
Loa Loa (eye worm) CXXC zinc finger family protein 0.0083 0.0218 0.0218
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0048 0.0102 0.0102
Trypanosoma brucei histone deacetylase 3 0.0038 0.0073 0.018
Echinococcus granulosus dro:myosuppressin receptor 0.0023 0.0023 0.0023
Echinococcus granulosus peregrin 0.002 0.0012 0.0012
Echinococcus granulosus histone acetyltransferase MYST2 0.0095 0.0255 0.0255
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0381 0.118 0.8221
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0019 0.0011 0.0011
Plasmodium falciparum thioredoxin reductase 0.0058 0.0135 0.1165
Schistosoma mansoni RAR-like nuclear receptor 0.0048 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0047 0.01 0.01
Schistosoma mansoni amine GPCR 0.0023 0.0023 0.0023
Mycobacterium ulcerans two component regulator - sensor kinase 0.007 0.0176 0.0968
Loa Loa (eye worm) hypothetical protein 0.3106 1 1
Echinococcus multilocularis tissue type plasminogen activator 0.004 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0078
Onchocerca volvulus 0.0023 0.0023 0.0152
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.002 0.0012 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0079 0.0197
Echinococcus granulosus tachykinin peptides receptor 99D 0.0023 0.0023 0.0023
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0169 0.0495 0.0495
Schistosoma mansoni histone deacetylase hda2 0.0044 0.0092 0.0092
Brugia malayi G protein-coupled receptor 0.0023 0.0023 0.0023
Treponema pallidum sodium- and chloride- dependent transporter 0.0081 0.0209 0.0688
Brugia malayi Amidase family protein 0.0375 0.1161 0.1161
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Entamoeba histolytica acyl-CoA synthetase, putative 0.0044 0.0091 0.0287
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0059 0.0139 0.0139
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0048 0.0102 0.0253
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trypanosoma cruzi heat shock protein 90, putative 0.007 0.0176 0.0435
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0363 0.1124 0.1124
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0007 0.0007
Mycobacterium leprae putative cytochrome p450 0.0135 0.0385 0.2218
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0019 0.0011 0.0011
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0021 0.0015 0.0015
Trypanosoma brucei Bromodomain, putative 0.002 0.0012 0.003
Loa Loa (eye worm) hypothetical protein 0.0144 0.0416 0.0416
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.2952 1
Loa Loa (eye worm) thioredoxin reductase 0.0167 0.0488 0.0488
Loa Loa (eye worm) CBP-B 0.002 0.0012 0.0012
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0375 0.1161 0.8075
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0124 0.035 0.1186
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0058 0.0135 0.0335
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0081 0.0209 0.0209
Mycobacterium ulcerans amidase 0.0375 0.1161 0.6606
Loa Loa (eye worm) hypothetical protein 0.0144 0.0416 0.0416
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0022 0.002 0.0049
Brugia malayi Bromodomain containing protein 0.002 0.0012 0.0012
Echinococcus multilocularis thyroid hormone receptor alpha 0.0048 0.0102 0.0102
Trichomonas vaginalis bromodomain containing protein, putative 0.002 0.0012 0.0041
Entamoeba histolytica ankyrin repeat protein, putative 0.002 0.0012 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Brugia malayi LBP/BPI 0.0126 0.0355 0.0355
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0492 0.1542 0.3805
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0167 0.0488 0.1644
Echinococcus multilocularis Bromodomain containing protein 0.002 0.0012 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0062 0.015 0.015
Toxoplasma gondii NADPH-glutathione reductase 0.0058 0.0135 0.0581
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0019 0.0011 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Schistosoma mansoni cpg binding protein 0.0099 0.027 0.027
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0019 0.0011 0.0013
Brugia malayi hypothetical protein 0.0046 0.0097 0.0097
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.1265 0.4041 0.4041
Echinococcus granulosus fatty acid amide hydrolase 1 0.3106 1 1
Brugia malayi nuclear receptor NHR-88 0.0048 0.0102 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0191
Trypanosoma brucei heat shock protein, putative 0.007 0.0176 0.0435
Giardia lamblia Serine peptidase, putative 0.0128 0.0362 0.1206
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.043 0.1064
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0059 0.0139 0.0344
Brugia malayi PHD-finger family protein 0.0158 0.0459 0.0459
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0023 0.0023
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.002 0.0049
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Brugia malayi hypothetical protein 0.0126 0.0355 0.0355
Trypanosoma brucei Bromodomain, putative 0.002 0.0012 0.003
Onchocerca volvulus DNA topoisomerase 2 homolog 0.007 0.0176 0.1159
Trypanosoma cruzi Bromodomain, putative 0.002 0.0012 0.003
Echinococcus multilocularis fatty acid amide hydrolase 1 0.3106 1 1
Brugia malayi nuclear hormone receptor 0.0021 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Echinococcus granulosus tissue type plasminogen activator 0.004 0.0078 0.0078
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0022 0.0022
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.0058 0.0058
Toxoplasma gondii heat shock protein 90, putative 0.007 0.0176 0.0755
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0107 0.0295 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0031
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0083 0.0218 0.0218
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0019 0.0011 0.0011
Onchocerca volvulus 0.002 0.0012 0.0079
Echinococcus granulosus lamin 0.0025 0.0029 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0135 0.0385 0.1291
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0023 0.0023
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.002 0.0012 0.0041
Schistosoma mansoni glutamate receptor kainate 0.0029 0.0041 0.0041
Plasmodium vivax bromodomain protein, putative 0.002 0.0012 0.0103
Plasmodium vivax glutathione reductase, putative 0.0167 0.0488 0.4206
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0057 0.0133 0.0429
Entamoeba histolytica bromodomain-containing protein 0.002 0.0012 0.0018
Loa Loa (eye worm) hypothetical protein 0.0126 0.0355 0.0355
Leishmania major 4-coumarate:coa ligase-like protein 0.0044 0.0091 0.021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0058 0.0135 0.0335
Trypanosoma brucei heat shock protein, putative 0.007 0.0176 0.0435
Mycobacterium ulcerans aldehyde dehydrogenase 0.0039 0.0073 0.0379
Trichomonas vaginalis hypothetical protein 0.002 0.0012 0.0041
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0058 0.0136 0.0136
Echinococcus multilocularis peregrin 0.002 0.0012 0.0012
Onchocerca volvulus 0.0169 0.0495 0.3266
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.007 0.0176 0.0595
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0035
Brugia malayi G-protein coupled receptor 0.0023 0.0023 0.0023
Brugia malayi Serotonin receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) MBCTL1 0.0095 0.0255 0.0255
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0183 0.054 0.054
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0015 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0102
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0091 0.0289
Onchocerca volvulus 0.0023 0.0023 0.0152
Echinococcus granulosus glutamate receptor 2 0.0023 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0144 0.0416 0.0416
Trichomonas vaginalis STE family protein kinase 0.0044 0.0092 0.031
Echinococcus multilocularis muscleblind protein 1 0.0239 0.0721 0.0721
Trypanosoma cruzi bromodomain-containing protein 3 0.002 0.0012 0.003
Schistosoma mansoni DNA topoisomerase II 0.007 0.0176 0.0176
Echinococcus granulosus FTZ F1 alpha 0.0048 0.0102 0.0102
Plasmodium falciparum zinc finger protein, putative 0.0021 0.0016 0.0142
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) bromodomain containing protein 0.011 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Onchocerca volvulus Brd8 homolog 0.002 0.0012 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Loa Loa (eye worm) serotonin transporter b 0.0081 0.0209 0.0209
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0058 0.0135 0.0319
Echinococcus multilocularis G protein coupled receptor 139 0.0023 0.0023 0.0023
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0058 0.0135 0.0736
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Brugia malayi Melatonin receptor type 1A 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0022 0.0022
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0375 0.1161 0.1161
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0007 0.0022
Echinococcus granulosus polybromo 1 0.002 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0126 0.0355 0.0355
Loa Loa (eye worm) heat shock protein 90 0.007 0.0176 0.0176
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1059 0.3376 0.8353
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Leishmania major developmentally regulated phosphoprotein-like protein 0.1265 0.4041 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0031
Brugia malayi Protein kinase domain containing protein 0.0041 0.008 0.008
Brugia malayi GnHR receptor homolog 0.0023 0.0023 0.0023
Leishmania major hypothetical protein, conserved 0.002 0.0012 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.0416 0.1408
Loa Loa (eye worm) hypothetical protein 0.0128 0.0362 0.0362
Echinococcus granulosus tumor protein p63 0.0324 0.0997 0.0997
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0016 0.0016
Trypanosoma cruzi cytochrome P450, putative 0.0278 0.0849 0.2101
Echinococcus granulosus somatostatin receptor 0.0023 0.0023 0.0023
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0025 0.0029 0.0029
Onchocerca volvulus 0.004 0.0078 0.0516
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0019 0.0011 0.0045
Brugia malayi Serine carboxypeptidase S28 family protein 0.0586 0.1844 0.1844
Onchocerca volvulus 0.0081 0.0209 0.138
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0007 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0191
Trypanosoma brucei cytochrome P450, putative 0.0278 0.0849 0.2101
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0009 0.0031
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0058 0.0135 0.0135
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Brugia malayi G protein-coupled receptor F59B2.13 0.0023 0.0023 0.0023
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Brugia malayi ecdysone receptor 0.0021 0.0016 0.0016
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0023 0.0023 0.0023
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0079 0.0269
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0263 0.0798 0.0798
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.1265 0.4041 1
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0012 0.003
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Onchocerca volvulus 0.0039 0.0073 0.048
Echinococcus granulosus hypothetical protein 0.0023 0.0023 0.0023
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0124 0.035 0.1186
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Brugia malayi Muscleblind-like protein 0.0239 0.0721 0.0721
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Echinococcus multilocularis G-protein coupled receptor, putative 0.0023 0.0023 0.0023
Echinococcus multilocularis ecdysone induced protein 78C 0.0048 0.0102 0.0102
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1265 0.4041 0.4041
Onchocerca volvulus 0.0021 0.0016 0.0104
Echinococcus granulosus peptide allatostatin:somatostatin 0.0023 0.0023 0.0023
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0007 0.0016
Entamoeba histolytica bromodomain-containing protein 0.002 0.0012 0.0018
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus multilocularis zinc finger protein 0.0126 0.0357 0.0357
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0019 0.0011 0.0011
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.0058 0.0058
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.007 0.0176 0.0639
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0375 0.1161 1
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Schistosoma mansoni phd finger protein 0.002 0.0012 0.0012
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0033 0.0055 0.0165
Giardia lamblia Kinase, STE STE20 0.0044 0.0092 0.0289
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0023 0.0023
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0058 0.0136 0.0136
Echinococcus multilocularis orexin receptor type 2 0.0023 0.0023 0.0023
Echinococcus multilocularis serotonin transporter 0.0081 0.0209 0.0209
Plasmodium vivax histone deacetylase, putative 0.0038 0.0073 0.0625
Echinococcus multilocularis polycomb protein SCMH1 0.0083 0.0218 0.0218
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0586 0.1844 0.1844
Echinococcus granulosus heat shock protein 90 0.007 0.0176 0.0176
Echinococcus multilocularis allatostatin A receptor 0.0023 0.0023 0.0023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0058 0.0135 0.0335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.002 0.0067
Onchocerca volvulus 0.0048 0.0102 0.0674
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0044 0.009 0.0223
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0055 0.0127 0.0429
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Brugia malayi Bromodomain containing protein 0.002 0.0012 0.0012
Plasmodium vivax hypothetical protein, conserved 0.007 0.0176 0.1514
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0128 0.0362 0.0362
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0019 0.0011 0.0091
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Toxoplasma gondii bromodomain-containing protein 0.002 0.0012 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0191
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0058 0.0135 0.0319
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0375 0.1161 0.1161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0315
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0019 0.0011 0.001
Mycobacterium ulcerans amidase 0.0375 0.1161 0.6606
Brugia malayi CXXC zinc finger family protein 0.0083 0.0218 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Schistosoma mansoni fatty-acid amide hydrolase 0.3106 1 1
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.007 0.0176 0.0968
Brugia malayi Dopamine receptor protein 1 0.0023 0.0023 0.0023
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Toxoplasma gondii histone lysine methyltransferase SET1 0.018 0.053 0.2278
Toxoplasma gondii hypothetical protein 0.0019 0.0011 0.0045
Brugia malayi Dopamine receptor protein 2 0.0023 0.0023 0.0023
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0375 0.1161 0.3918
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0135 0.0385 0.1291
Treponema pallidum NADH oxidase 0.0058 0.0135 0.0437
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Onchocerca volvulus 0.0083 0.0218 0.1437
Trichomonas vaginalis bromodomain-containing protein, putative 0.0083 0.0217 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.0058 0.0058
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0016 0.0016
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0012 0.0012
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0135 0.0385 0.1291
Schistosoma mansoni neuropeptide receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0048 0.0102 0.0674
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0124 0.035 0.0867
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0135 0.0385 0.2165
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0023 0.0023
Entamoeba histolytica bromodomain-containing protein 0.002 0.0012 0.0018
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0058 0.0135 0.0335
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0023 0.0023
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0074 0.0189 0.1628
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0023 0.0023
Schistosoma mansoni biogenic amine receptor 0.0023 0.0023 0.0023
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0442 0.1379 0.3402
Schistosoma mansoni neuropeptide receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0176 0.0435
Echinococcus multilocularis bromodomain containing 2 0.002 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0315
Brugia malayi DNA topoisomerase II, alpha isozyme 0.007 0.0176 0.0176
Trypanosoma cruzi bromodomain factor 2 protein 0.002 0.0012 0.003
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0212 0.0635 0.0635
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0031
Trypanosoma brucei developmentally regulated phosphoprotein 0.1265 0.4041 1
Onchocerca volvulus 0.0023 0.0023 0.0152
Onchocerca volvulus 0.0023 0.0023 0.0152
Loa Loa (eye worm) glutathione reductase 0.0167 0.0488 0.0488
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0016 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Plasmodium vivax DNA polymerase alpha, putative 0.0019 0.001 0.0083
Toxoplasma gondii aldehyde dehydrogenase 0.0039 0.0073 0.0313
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Echinococcus granulosus sex peptide receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis glutathione reductase, putative 0.0058 0.0135 0.0458
Toxoplasma gondii heat shock protein HSP90 0.007 0.0176 0.0755
Brugia malayi conserved hypotetical protein 0.0021 0.0016 0.0016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0049 0.0145
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0058 0.0135 0.1114
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Loa Loa (eye worm) TYRA-2 protein 0.0023 0.0023 0.0023
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0295 0.0903 0.0903
Trichomonas vaginalis heat shock protein, putative 0.007 0.0176 0.0595
Loa Loa (eye worm) hypothetical protein 0.0144 0.0416 0.0416
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0039 0.0073 0.0164
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0083 0.0217 0.0735
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.002 0.0067
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.007 0.0176 0.0578
Schistosoma mansoni glutamate receptor kainate 0.0029 0.0041 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Mycobacterium tuberculosis Conserved protein 0.0144 0.0416 0.1397
Brugia malayi ATPase, AAA family protein 0.002 0.0012 0.0012
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.002 0.0012 0.0013
Echinococcus multilocularis heat shock protein 0.007 0.0176 0.0176
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0423 0.1317 0.4475
Plasmodium falciparum histone acetyltransferase GCN5 0.0063 0.0153 0.1318
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0045 0.0095 0.0095
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0074 0.0189 0.0189
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0023 0.0023
Leishmania major hypothetical protein, conserved 0.0375 0.1161 0.286
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.007 0.0176 0.0595
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0128 0.0362 0.0896
Schistosoma mansoni bromodomain containing protein 0.002 0.0012 0.0012
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0058 0.0136 0.0438
Trichomonas vaginalis bromodomain containing protein, putative 0.002 0.0012 0.0041
Schistosoma mansoni zinc finger protein 0.009 0.0241 0.0241
Brugia malayi Cytochrome P450 family protein 0.0278 0.0849 0.0849
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Schistosoma mansoni histamine h1 receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0031
Brugia malayi Serotonin receptor 0.0023 0.0023 0.0023
Toxoplasma gondii bromodomain-containing protein 0.002 0.0012 0.0051
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0007 0.0007
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0045 0.0095 0.0095
Mycobacterium tuberculosis Conserved protein 0.007 0.0176 0.0578
Schistosoma mansoni pyruvate dehydrogenase 0.1194 0.3813 0.3813
Giardia lamblia Rab geranylgeranyltransferase 0.0019 0.0011 0.0013
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0442 0.1379 0.5921
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0144 0.0416 0.1397
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0128 0.0362 0.1226
Echinococcus multilocularis cpg binding protein 0.0099 0.027 0.027
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.007 0.0176 0.0578
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0019 0.0011 0.0091
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0023 0.0023
Echinococcus granulosus Bromodomain containing protein 0.002 0.0012 0.0012
Toxoplasma gondii hypothetical protein 0.002 0.0012 0.0051
Echinococcus granulosus 7tm_1 domain containing protein 0.0023 0.0023 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0047 0.0102 0.0102
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0022 0.0022
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0492 0.1542 0.5242
Schistosoma mansoni amine GPCR 0.0023 0.0023 0.0023
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0023 0.0023 0.0023
Onchocerca volvulus 0.0144 0.0416 0.2741
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0074 0.0189 0.0619
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Plasmodium vivax DNA topoisomerase II, putative 0.007 0.0176 0.1514
Loa Loa (eye worm) hypothetical protein 0.0143 0.0412 0.0412
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0058 0.0135 0.0736
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0031
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0058 0.0135 0.0335
Trichomonas vaginalis STE family protein kinase 0.0044 0.0092 0.031
Leishmania major hypothetical protein, conserved 0.0144 0.0416 0.1014
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0019 0.0011 0.0026
Echinococcus multilocularis 0.0135 0.0385 0.0385
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0375 0.1161 0.1161
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0169 0.0495 0.0495
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0442 0.1379 0.3412
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0375 0.1161 0.6606
Treponema pallidum fructose-bisphosphate aldolase 0.0928 0.2952 1
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.007 0.0176 0.0435
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0169 0.0495 0.0495
Echinococcus multilocularis lamin 0.0025 0.0029 0.0029
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0492 0.1542 0.8788
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0048 0.0102 0.0102
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0023 0.0023 0.0023
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Echinococcus granulosus histone deacetylase 7 0.0038 0.0073 0.0073
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0191
Onchocerca volvulus 0.0047 0.01 0.0657
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0023 0.0024 0.0024
Echinococcus multilocularis Bromodomain containing protein 0.002 0.0012 0.0012
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0381 0.118 0.4006
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0048 0.0102 0.0102
Treponema pallidum chemotaxis histidine kinase (cheA) 0.007 0.0176 0.0574
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0362 0.1226
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0023 0.0023
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0102 0.0346
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0074 0.0074
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0066 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0031
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0023 0.0023 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0048 0.0102 0.0102
Echinococcus multilocularis neuropeptide FF receptor 2 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0102
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0332 0.1022 0.1022
Brugia malayi Cytochrome P450 family protein 0.0278 0.0849 0.0849
Mycobacterium leprae Probable two-component sensor kinase 0.007 0.0176 0.0639
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0091 0.0091
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0023 0.0023
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0007 0.0016
Brugia malayi Bromodomain containing protein 0.002 0.0012 0.0012
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0423 0.1317 0.4475
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0453 0.1415 0.481
Trypanosoma cruzi Bromodomain, putative 0.002 0.0012 0.003
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0058 0.0135 0.1165
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0049 0.0108 0.0108
Trichomonas vaginalis lymphoid specific helicase, putative 0.002 0.0012 0.0041
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0023 0.0023
Onchocerca volvulus 0.002 0.0012 0.0079
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0023 0.0023 0.0023
Trypanosoma brucei heat shock protein, putative 0.007 0.0176 0.0435
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0012
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.007 0.0176 0.0755
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0021 0.0016 0.0033
Plasmodium falciparum thioredoxin reductase 0.0167 0.0488 0.4206
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0062 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0081 0.0209 0.0209
Trichomonas vaginalis heat shock protein, putative 0.007 0.0176 0.0595
Brugia malayi latrophilin 2 splice variant baaae 0.0027 0.0035 0.0035
Schistosoma mansoni sex comb on midleg homolog 0.0083 0.0218 0.0218
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus granulosus neuropeptide receptor A26 0.0023 0.0023 0.0023
Plasmodium falciparum cysteine repeat modular protein 1 0.004 0.0078 0.0674
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0032 0.0051 0.0151
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.007 0.0176 0.0968
Echinococcus granulosus neuropeptide s receptor 0.0023 0.0023 0.0023
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Toxoplasma gondii histone deacetylase HDAC1 0.0038 0.0073 0.0312
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1265 0.4041 0.4041
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0135 0.0385 0.0952
Leishmania major cytochrome p450-like protein 0.0278 0.0849 0.2088
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.007 0.0176 0.0435
Onchocerca volvulus 0.0019 0.0011 0.007
Echinococcus granulosus geminin 0.0403 0.1253 0.1253
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Onchocerca volvulus 0.0025 0.0029 0.0191
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0102
Trypanosoma brucei glucosidase, putative 0.0041 0.0079 0.0197
Entamoeba histolytica heat shock protein 90, putative 0.007 0.0176 0.0574
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trypanosoma cruzi Bromodomain, putative 0.002 0.0012 0.003
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0048 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0007 0.0057
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0095 0.0255 0.0255
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0135 0.0385 0.2165
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trichomonas vaginalis penicillin-binding protein, putative 0.0144 0.0416 0.1408
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0135 0.0385 0.2165
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0044 0.0091 0.0484
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0016 0.0016
Schistosoma mansoni polybromo-1 0.002 0.0012 0.0012
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0019 0.0011 0.0026
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0453 0.1415 1
Loa Loa (eye worm) hypothetical protein 0.0586 0.1844 0.1844
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.002 0.002
Trichomonas vaginalis mercuric reductase, putative 0.0058 0.0135 0.0458
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0111 0.0307 0.0307
Echinococcus granulosus histone lysine methyltransferase setb 0.0163 0.0477 0.0477
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0151 0.0151
Plasmodium falciparum heat shock protein 90 0.007 0.0176 0.1514
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0031
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0492 0.1542 0.3815
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0128 0.0362 0.0896
Echinococcus granulosus alpha 1A adrenergic receptor 0.0023 0.0023 0.0023
Leishmania major mitochondrial DNA polymerase beta 0.1059 0.3376 0.835
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Loa Loa (eye worm) phosphatidylinositol 3 0.0037 0.0067 0.0067
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0144 0.0416 0.0416
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.0058 0.0058
Trichomonas vaginalis sensor histidine kinase, putative 0.007 0.0176 0.0595
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0362 0.1226
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0019 0.0011 0.0026
Echinococcus granulosus intermediate filament protein 0.0025 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0091 0.0242 0.0242
Leishmania major mitochondrial DNA topoisomerase II 0.007 0.0176 0.0419
Brugia malayi heat shock protein 90 0.007 0.0176 0.0176
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.0097 0.024
Toxoplasma gondii bromodomain-containing protein 0.002 0.0012 0.0051
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Loa Loa (eye worm) cytochrome P450 0.0135 0.0385 0.0385
Loa Loa (eye worm) hypothetical protein 0.007 0.0176 0.0176
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0048 0.0102 0.0102
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0019 0.0011 0.0026
Mycobacterium ulcerans DNA gyrase subunit B 0.007 0.0176 0.0968
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0019 0.001 0.0041
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0023 0.0023 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Leishmania major hypothetical protein, conserved 0.007 0.0176 0.0419
Schistosoma mansoni hypothetical protein 0.004 0.0078 0.0078
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0016 0.0016
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0022 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Leishmania major 4-coumarate:coa ligase-like protein 0.0044 0.0091 0.021
Onchocerca volvulus 0.0091 0.0242 0.1599
Brugia malayi hypothetical protein 0.0027 0.0035 0.0035
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0023 0.0023
Onchocerca volvulus 0.0295 0.0903 0.5953
Leishmania major 4-coumarate:coa ligase-like protein 0.0044 0.0091 0.021
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0023 0.0023
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0035 0.0035
Brugia malayi larval opioid receptor 0.0023 0.0023 0.0023
Echinococcus multilocularis PH interacting protein 0.002 0.0012 0.0012
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.007 0.0176 0.0435
Schistosoma mansoni heat shock protein 0.007 0.0176 0.0176
Brugia malayi putative amidase 0.0375 0.1161 0.1161
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Giardia lamblia Hypothetical protein 0.002 0.0012 0.0018
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.002 0.0012 0.0051
Echinococcus multilocularis muscleblind protein 0.0239 0.0721 0.0721
Echinococcus multilocularis SAM and MBT domain containing protein 0.0083 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0246 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Giardia lamblia Heat shock protein HSP 90-alpha 0.007 0.0176 0.0574
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0102
Schistosoma mansoni endoplasmin 0.007 0.0176 0.0176
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0023 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Schistosoma mansoni glutamate receptor NMDA 0.0034 0.0058 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0139 0.047
Schistosoma mansoni ap endonuclease 0.0018 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0144 0.0416 0.1408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0102 0.0346
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0023 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0113 0.0382
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Echinococcus granulosus ecdysone induced protein 78C 0.0048 0.0102 0.0102
Brugia malayi G-protein coupled receptor 0.0023 0.0023 0.0023
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0375 0.1161 0.394
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0059 0.0139 0.0139
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0086 0.0228 0.0772
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0031
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0023 0.0023
Schistosoma mansoni alpha glucosidase 0.0041 0.0079 0.0079
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0062 0.015 0.015
Plasmodium falciparum histone deacetylase 2 0.0038 0.0073 0.0625
Toxoplasma gondii DNA topoisomerase 2, putative 0.007 0.0176 0.0755
Brugia malayi neuropeptide F receptor 0.0023 0.0023 0.0023
Toxoplasma gondii hypothetical protein 0.0171 0.0501 0.2151
Entamoeba histolytica heat shock protein 90, putative 0.007 0.0176 0.0574
Plasmodium falciparum histone deacetylase, putative 0.0038 0.0073 0.0625
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0278 0.0849 0.4822
Schistosoma mansoni cpg binding protein 0.0083 0.0218 0.0218
Plasmodium vivax cysteine repeat modular protein 1, putative 0.004 0.0078 0.0674
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.002 0.0012 0.0041
Schistosoma mansoni growth hormone secretagogue receptor 0.0023 0.0023 0.0023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0058 0.0135 0.0335
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1887 0.6055 0.6055
Onchocerca volvulus 0.0023 0.0023 0.0152
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0016 0.0016
Entamoeba histolytica acyl-coA synthetase, putative 0.0044 0.0091 0.0287
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.0079 0.0269
Giardia lamblia Thymus-specific serine protease precursor 0.0128 0.0362 0.1206
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0062 0.015 0.015
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0023 0.0023 0.0023
Echinococcus granulosus allatostatin A receptor 0.0023 0.0023 0.0023
Echinococcus granulosus zinc finger protein 0.0126 0.0357 0.0357
Trichomonas vaginalis DNA topoisomerase II, putative 0.007 0.0176 0.0595
Trypanosoma cruzi histone deacetylase, putative 0.0038 0.0073 0.018
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0135 0.0385 0.1291
Schistosoma mansoni neuropeptide f receptor 76f 0.0023 0.0023 0.0023
Mycobacterium tuberculosis Two component sensor kinase MprB 0.007 0.0176 0.0578
Loa Loa (eye worm) hypothetical protein 0.0083 0.0218 0.0218
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0169 0.0495 0.0495
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0058 0.0135 0.0335
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0044 0.0092 0.0211
Loa Loa (eye worm) cytochrome P450 family protein 0.0185 0.0545 0.0545
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0019 0.0011 0.0026
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0135 0.0385 0.2165
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0375 0.1161 0.394
Entamoeba histolytica bromodomain-containing protein 0.002 0.0012 0.0018
Echinococcus multilocularis polybromo 1 0.002 0.0012 0.0012
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus granulosus 7TM GPCR rhodopsin 0.0023 0.0023 0.0023
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0007 0.0007
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0059 0.0139 0.0449
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0048 0.0102 0.0102
Echinococcus granulosus thioredoxin glutathione reductase 0.0169 0.0495 0.0495
Loa Loa (eye worm) hypothetical protein 0.0058 0.0136 0.0136
Onchocerca volvulus 0.0023 0.0023 0.0152
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0036 0.0064 0.0064
Brugia malayi Bromodomain containing protein 0.002 0.0012 0.0012
Schistosoma mansoni histone deacetylase 4 5 0.0038 0.0073 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0135 0.0385 0.1291
Toxoplasma gondii histone acetyltransferase TAF1/250 0.002 0.0012 0.0051
Brugia malayi hypothetical protein 0.0169 0.0495 0.0495
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0102 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0031
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0029 0.0029
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.007 0.0176 0.1466
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0044 0.009 0.0306
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0035 0.0035
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0442 0.1379 0.3412
Onchocerca volvulus 0.0023 0.0023 0.0152
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0016 0.0016
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0035 0.0035
Onchocerca volvulus 0.0295 0.0903 0.5953
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0091 0.0484
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0144 0.0416 0.0416
Echinococcus granulosus neutral alpha glucosidase AB 0.0041 0.0079 0.0079
Loa Loa (eye worm) acetyltransferase 0.0249 0.0753 0.0753
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.007 0.0176 0.1466
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0149 0.043 0.1064
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0058 0.0135 0.0439
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0117 0.0327 0.1088
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0135 0.0385 0.2165
Brugia malayi ecdysteroid receptor 0.0111 0.0307 0.0307
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0016 0.0016
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0011 0.0026
Toxoplasma gondii kringle domain-containing protein 0.004 0.0078 0.0336
Trichomonas vaginalis receptor histidine kinase, putative 0.007 0.0176 0.0595
Plasmodium vivax endoplasmin, putative 0.007 0.0176 0.1514
Echinococcus granulosus serotonin transporter 0.0081 0.0209 0.0209
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0086 0.0228 0.0772
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0067 0.0226
Schistosoma mansoni heat shock protein 0.007 0.0176 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0023 0.0023
Plasmodium falciparum acyl-CoA synthetase 0.0033 0.0055 0.0474
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.002 0.0012 0.0079
Trypanosoma cruzi target of rapamycin kinase 3 0.0048 0.0102 0.0253
Schistosoma mansoni glutamate receptor AMPA 0.0029 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Brugia malayi nuclear receptor RXR 0.0021 0.0016 0.0016
Loa Loa (eye worm) histone deacetylase 0.0038 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0144 0.0416 0.0416
Giardia lamblia GTOR 0.0059 0.0139 0.0449
Mycobacterium tuberculosis Probable sensor protein KdpD 0.007 0.0176 0.0578
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0019 0.0011 0.0011
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0016 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0058 0.0136 0.0136
Brugia malayi Pre-SET motif family protein 0.0426 0.1326 0.1326
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0019 0.0011 0.0026
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Schistosoma mansoni glutamate receptor kainate 0.0029 0.0041 0.0041
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0009 0.0031
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0003 0.0012
Trichomonas vaginalis endoplasmin, putative 0.007 0.0176 0.0595
Mycobacterium ulcerans lipase LipD 0.0144 0.0416 0.2342
Echinococcus multilocularis glutamate receptor 2 0.0034 0.0058 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0079 0.0269
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Toxoplasma gondii target of rapamycin (TOR), putative 0.0045 0.0093 0.0399
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0023 0.0023
Trypanosoma brucei trypanothione reductase 0.0167 0.0488 0.1208
Echinococcus granulosus cytochrome P450 2K1 0.0135 0.0385 0.0385
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0074 0.0189 0.064
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0102 0.0346
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0128 0.0362 0.1206
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0044 0.0092 0.0092
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0058 0.0135 0.1165
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1059 0.3376 0.8353
Schistosoma mansoni nuclear receptor 0.0021 0.0016 0.0016
Echinococcus granulosus histone deacetylase 0.0038 0.0073 0.0073
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0027 0.0034 0.0084
Echinococcus multilocularis neuropeptide receptor A26 0.0023 0.0023 0.0023
Mycobacterium ulcerans esterase/lipase LipP 0.0144 0.0416 0.2342
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0079 0.0269
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0048 0.0102 0.0102
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.0416 0.1408
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0091 0.0484
Schistosoma mansoni cellular tumor antigen P53 0.0047 0.0102 0.0102
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0059 0.0139 0.0139
Echinococcus granulosus beta LACTamase domain containing family member 0.0144 0.0416 0.0416
Echinococcus multilocularis histone deacetylase 6 0.0038 0.0073 0.0073
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.007 0.0176 0.0435
Trypanosoma cruzi Heat shock protein 83, putative 0.007 0.0176 0.0435
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.007 0.0176 0.0176
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0039 0.0073 0.0073
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0381 0.118 0.4006
Loa Loa (eye worm) hypothetical protein 0.0239 0.0721 0.0721
Echinococcus granulosus muscleblind protein 0.0239 0.0721 0.0721
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0091 0.0242 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0191
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0044 0.009 0.0306
Plasmodium falciparum endoplasmin, putative 0.007 0.0176 0.1514
Loa Loa (eye worm) hypothetical protein 0.0081 0.0209 0.0209
Trichomonas vaginalis set domain proteins, putative 0.0484 0.1516 0.5136
Trypanosoma cruzi Bromodomain, putative 0.002 0.0012 0.003
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0102
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0062 0.015 0.015
Mycobacterium tuberculosis Possible two component sensor kinase 0.007 0.0176 0.0578
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.007 0.0176 0.0578
Schistosoma mansoni opsin-like receptor 0.0023 0.0023 0.0023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0049 0.0145
Loa Loa (eye worm) beta-lactamase 0.0144 0.0416 0.0416
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0453 0.1415 0.8065
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0019 0.0011 0.0011
Echinococcus granulosus histone deacetylase 6 0.0044 0.0092 0.0092
Trypanosoma brucei ISWI complex protein 0.009 0.0241 0.0596
Echinococcus granulosus bromodomain containing protein 8 0.002 0.0012 0.0012
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0044 0.0091 0.0289
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0044 0.0092 0.0092
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0081 0.0209 0.0209
Schistosoma mansoni hypothetical protein 0.0135 0.0385 0.0385
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0586 0.1844 0.1844
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0091 0.0091
Brugia malayi Serine protease Z688.6 precursor 0.0128 0.0362 0.0362
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0023 0.0023
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0138 0.0138
Schistosoma mansoni hypothetical protein 0.051 0.1599 0.1599
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0019 0.0011 0.0091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0058 0.0135 0.0335
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0059 0.0139 0.0139
Entamoeba histolytica acetyltransferase, GNAT family 0.0063 0.0153 0.0497
Trypanosoma brucei heat shock protein, putative 0.007 0.0176 0.0435
Trichomonas vaginalis receptor histidine kinase, putative 0.007 0.0176 0.0595
Brugia malayi beta-lactamase family protein 0.0144 0.0416 0.0416
Schistosoma mansoni coup transcription factor 0.0048 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0039 0.0075 0.0075
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0023 0.0024 0.0024
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0035
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0079 0.0269
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0044 0.0092 0.0227
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.003 0.0044 0.011
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0023 0.0023 0.0023
Trypanosoma cruzi histone deacetylase, putative 0.0038 0.0073 0.018
Schistosoma mansoni methyl-cpg binding protein mbd 0.0101 0.0274 0.0274
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0048 0.0102 0.0102
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0029 0.0029
Brugia malayi steroid hormone receptor 0.0048 0.0102 0.0102
Brugia malayi ORL1-like opioid receptor 0.0023 0.0023 0.0023
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.007 0.0176 0.0578
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.002 0.0012 0.0012
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0332 0.1022 0.1022
Brugia malayi Trypsin family protein 0.0047 0.01 0.01
Brugia malayi nuclear receptor RXR 0.0027 0.0035 0.0035
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Brugia malayi Dopamine receptor 0.0023 0.0023 0.0023
Giardia lamblia Transcription regulatory protein SNF2 0.002 0.0012 0.0018
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Mycobacterium ulcerans amidase 0.0375 0.1161 0.6606
Loa Loa (eye worm) hypothetical protein 0.0025 0.0029 0.0029
Onchocerca volvulus 0.0295 0.0903 0.5953
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0016 0.0104
Schistosoma mansoni aldehyde dehydrogenase 0.0039 0.0073 0.0073
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.002 0.0049
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus multilocularis fatty acid amide hydrolase 1 0.3106 1 1
Schistosoma mansoni endoplasmin 0.007 0.0176 0.0176
Echinococcus granulosus dual specificity mitogen activated protein 0.0044 0.0092 0.0092
Brugia malayi Bromodomain containing protein 0.002 0.0012 0.0012
Brugia malayi tailless protein 0.0021 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0446 0.1391 0.1391
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0058 0.0135 0.0135
Entamoeba histolytica hypothetical protein 0.01 0.027 0.0896
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0048 0.0102 0.0102
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0144 0.0416 0.1397
Loa Loa (eye worm) CYP4Cod1 0.0278 0.0849 0.0849
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0022 0.002 0.002
Echinococcus multilocularis dual specificity mitogen activated protein 0.0044 0.0092 0.0092
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0022 0.002 0.0049
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0295 0.0903 0.0903
Brugia malayi sulfakinin receptor protein 0.0023 0.0023 0.0023
Brugia malayi Cytochrome P450 family protein 0.0135 0.0385 0.0385
Giardia lamblia Histone acetyltransferase GCN5 0.0063 0.0153 0.0497
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0016 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Onchocerca volvulus 0.0023 0.0023 0.0152
Plasmodium falciparum DNA topoisomerase 2 0.007 0.0176 0.1514
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0044 0.009 0.0223
Schistosoma mansoni lamin 0.0025 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Echinococcus granulosus CREB binding protein 0.002 0.0012 0.0012
Brugia malayi Thioredoxin reductase 0.0167 0.0488 0.0488
Echinococcus multilocularis lamin dm0 0.0025 0.0029 0.0029
Entamoeba histolytica DNA topoisomerase II, putative 0.007 0.0176 0.0574
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Toxoplasma gondii cytochrome p450 superfamily protein 0.0736 0.2329 1
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0079 0.0197
Loa Loa (eye worm) hypothetical protein 0.0295 0.0903 0.0903
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0048 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0058 0.0135 0.0335
Trypanosoma cruzi amidase, putative 0.0375 0.1161 0.2872
Echinococcus granulosus CREB binding protein 0.002 0.0012 0.0012
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0128 0.0362 0.1226
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.002 0.0012 0.0013
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Mycobacterium ulcerans hypothetical protein 0.0044 0.0091 0.0484
Trypanosoma brucei heat shock protein, putative 0.007 0.0176 0.0435
Brugia malayi Tachykinin-like peptides receptor 99D 0.0023 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0381 0.118 0.4006
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0144 0.0416 0.0416
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0058 0.0136 0.0136
Echinococcus multilocularis neuropeptide s receptor 0.0023 0.0023 0.0023
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0048 0.0102 0.0102
Plasmodium vivax ataxin-2 like protein, putative 0.0046 0.0097 0.0835
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0022 0.002 0.002
Trypanosoma cruzi Bromodomain factor 1 0.002 0.0012 0.003
Mycobacterium tuberculosis Probable lipase LipD 0.0144 0.0416 0.1397
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus granulosus histone acetyltransferase KAT2B 0.0083 0.0217 0.0217
Echinococcus granulosus polycomb protein SCMH1 0.0083 0.0218 0.0218
Onchocerca volvulus 0.0063 0.0151 0.0995
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0023 0.0023
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0023 0.0023 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0144 0.0416 0.1029
Echinococcus granulosus neuropeptide FF receptor 2 0.0023 0.0023 0.0023
Echinococcus granulosus sodium channel protein 0.0025 0.0029 0.0029
Brugia malayi bromodomain containing protein 0.002 0.0012 0.0012
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0023 0.0023
Mycobacterium tuberculosis Probable two component sensor kinase 0.007 0.0176 0.0578
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0044 0.0091 0.0484
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0045 0.0095 0.0095
Trichomonas vaginalis bromodomain containing protein, putative 0.002 0.0012 0.0041
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0074 0.0189 0.0189
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0135 0.0385 0.1291
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0031
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0058 0.0135 0.0135
Schistosoma mansoni zinc finger protein 0.0126 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0135 0.0385 0.2165
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0418 0.1301 0.1301
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0223 0.0669 0.0669
Mycobacterium ulcerans aldehyde dehydrogenase 0.0039 0.0073 0.0379
Brugia malayi putative neuropeptide receptor NPR1 0.0023 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0315
Plasmodium vivax hypothetical protein, conserved 0.0144 0.0416 0.3581
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0019 0.0011 0.0036
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.007 0.0176 0.1466
Brugia malayi Histone deacetylase family protein 0.0038 0.0073 0.0073
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0023 0.0023 0.0023
Schistosoma mansoni zinc finger protein 0.0021 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0169 0.0495 0.0495
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0016 0.0016
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0044 0.0091 0.0484
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0928 0.2952 1
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Brugia malayi Bromodomain containing protein 0.0454 0.1417 0.1417
Plasmodium vivax heat shock protein 86, putative 0.007 0.0176 0.1514
Brugia malayi hypothetical protein 0.0169 0.0495 0.0495
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Giardia lamblia NADH oxidase lateral transfer candidate 0.0058 0.0135 0.0437
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0048 0.0102 0.0102
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0102 0.0102
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0135 0.0385 0.1291
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0082 0.0213 0.0213
Loa Loa (eye worm) hypothetical protein 0.0044 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0035 0.0035
Schistosoma mansoni biogenic amine receptor 0.0023 0.0023 0.0023
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0144 0.0416 0.1397
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Schistosoma mansoni ap endonuclease 0.0018 0.0007 0.0007
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0048 0.0102 0.0102
Schistosoma mansoni helicase 0.002 0.0012 0.0012
Onchocerca volvulus 0.0044 0.0091 0.0601
Onchocerca volvulus 0.0295 0.0903 0.5953
Brugia malayi nuclear hormone receptor 0.0048 0.0102 0.0102
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Schistosoma mansoni alpha-glucosidase 0.0157 0.0458 0.0458
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0501 0.157 0.3886
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Loa Loa (eye worm) solute carrier family 6 member 4 0.0081 0.0209 0.0209
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0128 0.0362 0.0362
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0019 0.0011 0.0091
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0135 0.0385 0.2165
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.007 0.0176 0.0578
Mycobacterium tuberculosis Conserved hypothetical protein 0.0558 0.1753 0.5965
Trypanosoma brucei heat shock protein 90, putative 0.007 0.0176 0.0435
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0048 0.0102 0.0237
Mycobacterium tuberculosis Probable reductase 0.0381 0.118 0.4006
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0086
Schistosoma mansoni bromodomain containing 0.002 0.0012 0.0012
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.007 0.0176 0.0578
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0035
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0019 0.0011 0.0013
Echinococcus granulosus histone acetyltransferase KAT2B 0.0228 0.0687 0.0687
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0101 0.0274 0.0274
Schistosoma mansoni retinoic acid receptor RXR 0.0048 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.007 0.0176 0.0176
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0062 0.015 0.015
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0058 0.0135 0.0581
Echinococcus granulosus methyl CpG binding domain protein 2 0.0101 0.0274 0.0274
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0032 0.0052 0.0345
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0025 0.0029 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.002 0.0067
Schistosoma mansoni survival motor neuron protein 0.0091 0.0242 0.0242
Brugia malayi hypothetical protein 0.003 0.0044 0.0044
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.002 0.0012 0.0012
Schistosoma mansoni myst-related protein 0.0021 0.0016 0.0016
Brugia malayi Cytochrome P450 family protein 0.0185 0.0545 0.0545
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0023 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.002 0.0012 0.0018
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0074 0.0189 0.064
Brugia malayi putative neuropeptide receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0136 0.0136
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0048 0.0102 0.0102
Schistosoma mansoni amine GPCR 0.0023 0.0023 0.0023
Brugia malayi glutathione reductase 0.0167 0.0488 0.0488
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0082 0.0213 0.0213
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0034 0.0058 0.0058
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0231 0.0694 0.0694
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0023 0.0023
Echinococcus granulosus neuropeptide receptor 0.0023 0.0023 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0928 0.2952 1
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0375 0.1161 0.1161
Brugia malayi DNA polymerase alpha catalytic subunit 0.0019 0.001 0.001
Echinococcus granulosus g-protein coupled receptor 0.0023 0.0023 0.0023
Onchocerca volvulus 0.0023 0.0023 0.0152
Brugia malayi beta-lactamase family protein 0.0144 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Loa Loa (eye worm) TK/ROR protein kinase 0.0041 0.008 0.008
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0375 0.1161 1
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.007 0.0176 0.0968
Plasmodium falciparum glutathione reductase 0.0058 0.0135 0.1165
Onchocerca volvulus 0.0295 0.0903 0.5953
Onchocerca volvulus 0.0126 0.0355 0.2344
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0024 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.0416 0.1408
Loa Loa (eye worm) melatonin receptor type 1A 0.0023 0.0023 0.0023
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Schistosoma mansoni alpha-1 adrenergic receptor 0.0023 0.0023 0.0023
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0044 0.009 0.009
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0039 0.0075 0.0075
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0923 0.2935 1
Trypanosoma cruzi Bromodomain, putative 0.002 0.0012 0.003
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Schistosoma mansoni hypothetical protein 0.0023 0.0023 0.0023
Entamoeba histolytica bromodomain-containing protein 0.002 0.0012 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0126 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0032 0.0052 0.0052
Onchocerca volvulus 0.0485 0.1516 1
Trypanosoma brucei heat shock protein, putative 0.007 0.0176 0.0435
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0007 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0091 0.0091
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0042 0.0086 0.0086
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0135 0.0385 0.2165
Echinococcus multilocularis serotonin receptor 0.0023 0.0023 0.0023
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0138 0.0395 0.0395
Echinococcus granulosus fatty acid amide hydrolase 1 0.0375 0.1161 0.1161
Loa Loa (eye worm) cytochrome P450 family protein 0.0278 0.0849 0.0849
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0083 0.0217 0.0931
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0139 0.047
Loa Loa (eye worm) hypothetical protein 0.0074 0.0189 0.0189
Echinococcus multilocularis lysosomal alpha glucosidase 0.0183 0.054 0.054
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0048 0.0102 0.0102
Echinococcus multilocularis lysosomal alpha glucosidase 0.0183 0.054 0.054
Echinococcus multilocularis heat shock protein 90 0.007 0.0176 0.0176
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0163 0.0477 0.0477
Onchocerca volvulus 0.0023 0.0023 0.0152
Mycobacterium leprae Conserved hypothetical protein 0.0135 0.0385 0.2218
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.009 0.009
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.0058 0.0058
Schistosoma mansoni myosin xvIII 0.0023 0.0023 0.0023
Loa Loa (eye worm) endoplasmin 0.007 0.0176 0.0176
Trichomonas vaginalis sucrase-isomaltase, putative 0.0041 0.0079 0.0269
Trypanosoma brucei bromodomain factor 2 protein, putative 0.002 0.0012 0.003
Plasmodium vivax SET domain protein, putative 0.0063 0.0151 0.13
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0501 0.157 0.3876
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0423 0.1317 0.9259
Toxoplasma gondii thioredoxin reductase 0.0167 0.0488 0.2096
Echinococcus granulosus histone deacetylase 6 0.0038 0.0073 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0066 0.0222
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0044 0.009 0.0284
Leishmania major DNA topoisomerase ii 0.007 0.0176 0.0419
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.002 0.0012 0.0041
Plasmodium vivax bromodomain protein, putative 0.002 0.0012 0.0103
Echinococcus multilocularis protein kinase C binding protein 1 0.002 0.0012 0.0012
Schistosoma mansoni opsin-like receptor 0.0023 0.0023 0.0023
Onchocerca volvulus 0.0023 0.0023 0.0152
Leishmania major hypothetical protein, conserved 0.004 0.0078 0.0178
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.0097 0.0835
Schistosoma mansoni hypothetical protein 0.0122 0.0343 0.0343
Trypanosoma cruzi heat shock protein 85, putative 0.007 0.0176 0.0435
Plasmodium falciparum bromodomain protein 2, putative 0.002 0.0012 0.0103
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0033 0.0055 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Schistosoma mansoni hypothetical protein 0.1187 0.3791 0.3791
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0022 0.0022
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0016 0.0016
Schistosoma mansoni sex comb on midleg homolog 0.0083 0.0218 0.0218
Trypanosoma cruzi trypanothione reductase, putative 0.0058 0.0135 0.0335
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0035
Toxoplasma gondii bromodomain-containing protein 0.002 0.0012 0.0051
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.2952 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.007 0.0176 0.0968
Echinococcus multilocularis somatostatin receptor 0.0023 0.0023 0.0023
Trypanosoma brucei heat shock protein 90, putative 0.007 0.0176 0.0435
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0102 0.0102
Loa Loa (eye worm) glutamate receptor 1 0.0029 0.0041 0.0041
Echinococcus multilocularis survival motor neuron protein 1 0.0446 0.1391 0.1391
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Trypanosoma brucei heat shock protein, putative 0.007 0.0176 0.0435
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0249 0.0753 0.0753
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0102 0.0102
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0016 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.2952 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0007 0.0016
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0149 0.043 0.1064
Onchocerca volvulus 0.0023 0.0023 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Brugia malayi kinase, mitochondrial precursor 0.1265 0.4041 0.4041
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0044 0.0091 0.0484
Plasmodium falciparum bromodomain protein 1 0.002 0.0012 0.0103
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0058 0.0135 0.0319
Schistosoma mansoni myst-related protein 0.0021 0.0016 0.0016
Echinococcus granulosus lamin dm0 0.0025 0.0029 0.0029
Entamoeba histolytica bromodomain-containing protein 0.002 0.0012 0.0018
Brugia malayi Bromodomain containing protein 0.002 0.0012 0.0012
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Schistosoma mansoni pyruvate dehydrogenase 0.1194 0.3813 0.3813
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0058 0.0135 0.0335
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0135 0.0385 0.2165
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Mycobacterium ulcerans peptide amidase, GatA 0.0375 0.1161 0.6606
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0048 0.0102 0.0102
Toxoplasma gondii ABC1 family protein 0.0144 0.0416 0.1785
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0375 0.1161 1
Loa Loa (eye worm) hypothetical protein 0.0169 0.0495 0.0495
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0381 0.118 0.4006
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0375 0.1161 0.8075
Trypanosoma cruzi heat shock protein 90, putative 0.007 0.0176 0.0435
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0102 0.0102
Brugia malayi Serine protease Z688.6 precursor 0.0128 0.0362 0.0362
Plasmodium vivax DNA gyrase subunit B, putative 0.007 0.0176 0.1514
Onchocerca volvulus 0.0144 0.0416 0.2741
Onchocerca volvulus 0.0047 0.0102 0.067
Echinococcus granulosus lysosomal alpha glucosidase 0.0183 0.054 0.054
Echinococcus multilocularis serotonin receptor 0.0023 0.0023 0.0023
Onchocerca volvulus 0.0023 0.0023 0.0152
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0011 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Loa Loa (eye worm) amidase 0.0375 0.1161 0.1161
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0019 0.0011 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0062 0.015 0.015
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0586 0.1844 0.1844
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0023 0.0023 0.0023
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0135 0.0385 0.2165
Brugia malayi follicle stimulating hormone receptor 0.0023 0.0023 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0023 0.0023
Trypanosoma cruzi amidase, putative 0.0375 0.1161 0.2872
Giardia lamblia Hypothetical protein 0.002 0.0012 0.0018
Brugia malayi hypothetical protein 0.0021 0.0016 0.0016
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Leishmania major hypothetical protein, conserved 0.002 0.0012 0.0013
Trypanosoma brucei DNA topoisomerase II beta, putative 0.007 0.0176 0.0435
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0054
Echinococcus multilocularis 0.002 0.0012 0.0012
Onchocerca volvulus Neuropeptide F receptor homolog 0.0023 0.0023 0.0152
Trypanosoma cruzi ISWI complex protein 0.009 0.0241 0.0596
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0007 0.0007
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.0097 0.024
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0059 0.0139 0.0328
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0019 0.0011 0.0011
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0074 0.0189 0.1628
Echinococcus granulosus Bromodomain containing protein 0.002 0.0012 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0135 0.0385 0.1291
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0135 0.0385 0.2165
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Schistosoma mansoni lamin 0.0025 0.0029 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0023 0.0023
Echinococcus granulosus bromodomain containing 2 0.002 0.0012 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0135 0.0385 0.1291
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0023 0.0023 0.0023
Echinococcus multilocularis histone deacetylase 0.0038 0.0073 0.0073
Mycobacterium ulcerans amidase 0.0375 0.1161 0.6606
Loa Loa (eye worm) mbt repeat family protein 0.0083 0.0218 0.0218
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus granulosus g protein coupled receptor 0.0023 0.0023 0.0023
Schistosoma mansoni amidase 0.3106 1 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0492 0.1542 0.3815
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.0058 0.0058
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0375 0.1161 0.394
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0012
Echinococcus multilocularis bromodomain containing protein 8 0.002 0.0012 0.0012
Brugia malayi cytochrome P450 0.0135 0.0385 0.0385
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0016 0.0016
Loa Loa (eye worm) norepinephrine transporter 0.0081 0.0209 0.0209
Brugia malayi hypothetical protein 0.0027 0.0035 0.0035
Mycobacterium ulcerans amidase 0.0375 0.1161 0.6606
Giardia lamblia Fructose-bisphosphate aldolase 0.0928 0.2952 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0058 0.0135 0.0736
Echinococcus multilocularis musashi 0.0025 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0135 0.0385 0.2165
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Brugia malayi polybromodomain protein 0.002 0.0012 0.0012
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0039 0.0039
Schistosoma mansoni bromodomain containing protein 0.0036 0.0064 0.0064
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.002 0.0067
Brugia malayi mbt repeat family protein 0.0083 0.0218 0.0218
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0023 0.0023
Brugia malayi photoreceptor-specific nuclear receptor 0.0048 0.0102 0.0102
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0128 0.0362 0.1206
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0079 0.0247
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0095 0.0255 0.0255
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0058 0.0135 0.0319
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0375 0.1161 0.2872
Echinococcus granulosus heat shock protein 0.007 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0135 0.0385 0.2165
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0048 0.0102 0.0102
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0135 0.0385 0.2165
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0102 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0139 0.047
Trypanosoma cruzi DNA topoisomerase II, putative 0.007 0.0176 0.0435
Echinococcus granulosus survival motor neuron protein 1 0.0446 0.1391 0.1391
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Leishmania major alpha glucosidase II subunit, putative 0.0041 0.0079 0.0181
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.007 0.0176 0.0578
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0019 0.0011 0.0036
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0124 0.035 0.035
Schistosoma mansoni sodium/chloride dependent transporter 0.0081 0.0209 0.0209
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0135 0.0385 0.1291
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus multilocularis histone deacetylase 6 0.0044 0.0092 0.0092
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0375 0.1161 0.394
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0082 0.0213 0.0213
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.007 0.0176 0.0595
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0135 0.0385 0.1291
Onchocerca volvulus 0.0023 0.0023 0.0152
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0135 0.0385 0.2165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0315
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0135 0.0385 0.2165
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0135 0.0385 0.2165
Trichomonas vaginalis hypothetical protein 0.002 0.0012 0.0041
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.01 0.027 0.0896
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Schistosoma mansoni CREB-binding protein 2 0.002 0.0012 0.0012
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0023 0.0023
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0163 0.0477 0.0477
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0128 0.0362 0.1226
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Brugia malayi beta-lactamase 0.0144 0.0416 0.0416
Onchocerca volvulus 0.002 0.0012 0.0079
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0039 0.0073 0.0226
Onchocerca volvulus 0.0023 0.0023 0.0152
Schistosoma mansoni nuclear receptor 0.0021 0.0016 0.0016
Mycobacterium tuberculosis Conserved protein 0.0144 0.0416 0.1397
Onchocerca volvulus 0.0083 0.0218 0.1436
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0049 0.0145
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0128 0.0362 0.0362
Echinococcus multilocularis tumor protein p63 0.0324 0.0997 0.0997
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0315
Loa Loa (eye worm) hypothetical protein 0.0027 0.0035 0.0035
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0095 0.0255 0.0255
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.002 0.0012 0.0012
Mycobacterium ulcerans two component sensor kinase MprB 0.007 0.0176 0.0968
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0023 0.0023 0.0023
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0151 0.0648
Loa Loa (eye worm) hypothetical protein 0.0169 0.0495 0.0495
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0023
Schistosoma mansoni intermediate filament proteins 0.0025 0.0029 0.0029
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0135 0.0385 0.1291
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0048 0.0102 0.0102
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0135 0.0385 0.1291
Schistosoma mansoni protein kinase 0.0044 0.0092 0.0092
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0106 0.0292 0.0292
Trichomonas vaginalis helicase, putative 0.0019 0.0009 0.0031
Echinococcus granulosus orexin receptor type 2 0.0023 0.0023 0.0023
Trichomonas vaginalis bromodomain containing protein, putative 0.002 0.0012 0.0041
Brugia malayi Steroid receptor seven-up type 2 0.0048 0.0102 0.0102
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0023 0.0023
Schistosoma mansoni bromodomain containing protein 0.0384 0.1192 0.1192
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0023 0.0023
Schistosoma mansoni ATP-binding cassette transporter 0.0029 0.0041 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.002 0.0067
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0019 0.0011 0.0011
Echinococcus multilocularis histone deacetylase 6 0.0038 0.0073 0.0073
Schistosoma mansoni neuropeptide receptor 0.0023 0.0023 0.0023
Trichomonas vaginalis bromodomain containing protein, putative 0.002 0.0012 0.0041
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.007 0.0176 0.0595
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.002 0.0012 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0135 0.0385 0.1291
Loa Loa (eye worm) phosphatidylinositol 3 0.0206 0.0614 0.0614
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Onchocerca volvulus 0.002 0.0013 0.0087
Schistosoma mansoni opsin-like receptor 0.0023 0.0023 0.0023
Plasmodium falciparum DNA gyrase subunit B 0.007 0.0176 0.1514
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0128 0.0362 0.0896
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0067 0.0226
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0048 0.0102 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0239 0.0721 0.0721
Loa Loa (eye worm) glutamate receptor 2 0.0029 0.0041 0.0041
Toxoplasma gondii bromodomain-containing protein 0.002 0.0012 0.0051
Onchocerca volvulus 0.0295 0.0903 0.5953
Schistosoma mansoni hypothetical protein 0.0023 0.0023 0.0023
Toxoplasma gondii hypothetical protein 0.0055 0.0127 0.0543
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0079 0.0269
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0048 0.0102 0.0102
Echinococcus multilocularis histone acetyltransferase MYST2 0.0095 0.0255 0.0255
Plasmodium vivax acyl-CoA synthetase, putative 0.0033 0.0055 0.0474
Loa Loa (eye worm) BRM protein 0.002 0.0012 0.0012
Schistosoma mansoni glutamate receptor NMDA 0.0107 0.0295 0.0295
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0928 0.2952 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0048 0.0102 0.0102
Trypanosoma brucei DNA topoisomerase ii 0.007 0.0176 0.0435
Brugia malayi RE15519p 0.0023 0.0023 0.0023
Onchocerca volvulus 0.0169 0.0495 0.3266
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1059 0.3376 0.8353
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0019 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0163 0.0477 0.0477
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0375 0.1161 1
Echinococcus multilocularis global transcription activator snf2l2 0.002 0.0012 0.0012
Loa Loa (eye worm) steroid hormone receptor 0.0048 0.0102 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0315
Onchocerca volvulus 0.0106 0.029 0.1916
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Trypanosoma brucei histone deacetylase 4 0.0038 0.0073 0.018
Leishmania major hypothetical protein, conserved 0.009 0.0241 0.058
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0128 0.0362 0.1226
Giardia lamblia Rab geranylgeranyltransferase 0.0074 0.0189 0.0619
Brugia malayi Pre-SET motif family protein 0.0063 0.0151 0.0151
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0042 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0169 0.0495 0.0495
Schistosoma mansoni hypothetical protein 0.0023 0.0023 0.0023
Trypanosoma brucei Heat shock protein 83, putative 0.007 0.0176 0.0435
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0019 0.0011 0.0026
Toxoplasma gondii exonuclease III APE 0.0018 0.0007 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0102 0.0102
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0135 0.0385 0.1291
Mycobacterium ulcerans hypothetical protein 0.0144 0.0416 0.2342
Brugia malayi Bromodomain containing protein 0.002 0.0012 0.0012
Echinococcus multilocularis geminin 0.0403 0.1253 0.1253
Loa Loa (eye worm) hypothetical protein 0.0144 0.0416 0.0416
Onchocerca volvulus 0.0023 0.0023 0.0152
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0023 0.0023
Echinococcus multilocularis beta LACTamase domain containing family member 0.0144 0.0416 0.0416
Trypanosoma cruzi cytochrome P450, putative 0.0278 0.0849 0.2101
Loa Loa (eye worm) amidase 0.0375 0.1161 0.1161
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0181 0.0535 0.1325
Brugia malayi neuropeptide F receptor 0.0023 0.0023 0.0023
Echinococcus granulosus protein kinase C binding protein 1 0.002 0.0012 0.0012
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.007 0.0176 0.0755
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.008 0.0271
Leishmania major heat shock protein 83-1 0.007 0.0176 0.0419
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0023 0.0023
Plasmodium vivax hypothetical protein, conserved 0.002 0.0012 0.0103
Echinococcus multilocularis FTZ F1 alpha 0.0048 0.0102 0.0102
Echinococcus granulosus G protein coupled receptor 139 0.0023 0.0023 0.0023
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0023 0.0023
Mycobacterium leprae conserved hypothetical protein 0.0144 0.0416 0.245
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0023 0.0023 0.0023
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.007 0.0176 0.0968
Trypanosoma brucei hypothetical protein, conserved 0.0144 0.0416 0.1029
Loa Loa (eye worm) hypothetical protein 0.0081 0.0209 0.0209
Giardia lamblia Kinase, putative 0.002 0.0012 0.0018
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0023 0.0023
Onchocerca volvulus 0.0021 0.0016 0.0104
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0016 0.0016
Brugia malayi Histone deacetylase family protein 0.0038 0.0073 0.0073
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0059 0.0139 0.0344
Mycobacterium tuberculosis Probable lipase LipE 0.0144 0.0416 0.1397
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.007 0.0176 0.0968
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0124 0.035 0.1167
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0492 0.1542 0.3815
Trichomonas vaginalis bromodomain-containing protein, putative 0.002 0.0012 0.0041
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0023 0.0023 0.0023
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.007 0.0176 0.0574
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0062 0.015 0.0643
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0021 0.0015 0.0015
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0079 0.0247
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0016 0.0016
Echinococcus granulosus SAM and MBT domain containing protein 0.0083 0.0218 0.0218
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0023 0.0023
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0019 0.0011 0.0011
Schistosoma mansoni SET domain protein 0.002 0.0013 0.0013
Echinococcus granulosus g protein coupled receptor 0.0023 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0044 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.1265 0.4041 0.4041
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0048 0.0102 0.0102
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0144 0.0416 0.2342
Echinococcus granulosus PH interacting protein 0.002 0.0012 0.0012
Echinococcus multilocularis neutral alpha glucosidase AB 0.0041 0.0079 0.0079
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0102 0.0102
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0058 0.0135 0.0335
Brugia malayi hypothetical protein 0.0023 0.0023 0.0023
Leishmania major phosphatidylinositol 3-kinase, putative 0.0022 0.002 0.0033

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 24800 nM Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells ChEMBL. 16134937
IC50 (binding) = 24800 nM Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cells ChEMBL. 16134937

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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