Detailed information for compound 438774

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 438.069 | Formula: C16H10BrCl2F3N2
  • H donors: 0 H acceptors: 1 LogP: 6.39 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1ccccc1Cn1c(nc2c1cc(Cl)c(c2)Cl)CC(F)(F)F
  • InChi: 1S/C16H10BrCl2F3N2/c17-10-4-2-1-3-9(10)8-24-14-6-12(19)11(18)5-13(14)23-15(24)7-16(20,21)22/h1-6H,7-8H2
  • InChiKey: HELIQQDGEGVWDV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0246 0.0672 0.1357
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0068 0.0149 0.03
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0011 0.0023
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0149 0.0302
Schistosoma mansoni cytochrome P450 0.0022 0.0011 0.0018
Trichomonas vaginalis abcb9, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Schistosoma mansoni regulator of G protein signaling 0.0046 0.0081 0.0128
Echinococcus multilocularis tubulin epsilon chain 0.0967 0.2801 0.2801
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0098
Echinococcus multilocularis Tubulin alpha 1 chain 0.1292 0.376 0.376
Toxoplasma gondii exonuclease III APE 0.002 0.0005 0.001
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0208 0.0562 0.0886
Schistosoma mansoni tubulin subunit alpha 0.0423 0.1194 0.1884
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.008 0.0183 0.15
Schistosoma mansoni hypothetical protein 0.0085 0.0197 0.0311
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0034 0.0069
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0134 0.0212
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0039 0.0069
Loa Loa (eye worm) nuclear factor I 0.0023 0.0016 0.0032
Schistosoma mansoni Smad4 0.0019 0.0003 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0144 0.0291
Loa Loa (eye worm) hypothetical protein 0.006 0.0125 0.0253
Loa Loa (eye worm) CYP4Cod1 0.0067 0.0144 0.0291
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0039 0.0286
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0011 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0156 0.0315
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0076 0.017 0.0335
Schistosoma mansoni loxhd1 0.0163 0.0427 0.0674
Treponema pallidum fructose-bisphosphate aldolase 0.029 0.0803 0.671
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0187 0.0498 0.0785
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0022 0.0022
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0288 0.235
Mycobacterium ulcerans endonuclease IV 0.008 0.0183 0.15
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0088
Schistosoma mansoni ap endonuclease 0.002 0.0005 0.0008
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.0013 0.0025
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0053 0.0104 0.0104
Trichomonas vaginalis tubulin alpha chain, putative 0.0516 0.1471 0.2972
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0044 0.0044
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0003 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0068 0.0149 0.0234
Trypanosoma cruzi trypanothione reductase, putative 0.0099 0.024 0.0485
Brugia malayi conserved hypotetical protein 0.003 0.0034 0.0069
Brugia malayi MH1 domain containing protein 0.0023 0.0016 0.0032
Trichomonas vaginalis abcb9, putative 0.0022 0.0013 0.0025
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0034 0.0054
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0226 0.0226
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0252 0.069 0.5747
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0011 0.0055
Loa Loa (eye worm) tubulin beta chain 0.0423 0.1194 0.2413
Brugia malayi sodium-independent organic anion transporter family protein 0.0088 0.0208 0.042
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Echinococcus multilocularis Smad4 0.0042 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0106 0.0259 0.0524
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0142 0.0224
Schistosoma mansoni alpha tubulin 0.1292 0.376 0.5931
Echinococcus multilocularis 0.0022 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0187 0.0498 0.1006
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0054 0.0106 0.0215
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0053 0.0104 0.0209
Entamoeba histolytica hypothetical protein 0.0187 0.0498 0.1006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0022 0.0034
Brugia malayi nuclear receptor NHR-88 0.0068 0.0149 0.03
Onchocerca volvulus 0.0088 0.0208 0.0969
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0003 0.0004
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0005 0.0005
Schistosoma mansoni lipoxygenase 0.0358 0.1003 0.1583
Echinococcus multilocularis mitogen activated protein kinase 3 0.0107 0.0262 0.0262
Schistosoma mansoni nuclear hormone receptor 0.003 0.0034 0.0054
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0038 0.0038
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.0081 0.0164
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0068 0.0149 0.0234
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0048 0.0366
Echinococcus granulosus Tubulin beta 2C chain 0.1695 0.4948 0.7805
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Leishmania major beta tubulin 0.1695 0.4948 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0015 0.0031
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0034 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0187 0.0377
Schistosoma mansoni nuclear receptor 0.003 0.0034 0.0054
Schistosoma mansoni follistatin 0.006 0.0125 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0078 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0068 0.0149 0.03
Leishmania major beta tubulin 0.1695 0.4948 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0061 0.0097
Trichomonas vaginalis tubulin epsilon chain, putative 0.0423 0.1194 0.2413
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Trichomonas vaginalis set domain proteins, putative 0.0737 0.2122 0.4289
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0227 0.0616 0.5117
Leishmania major beta tubulin 0.1695 0.4948 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0048 0.0366
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis tubulin epsilon chain, putative 0.1292 0.376 0.7599
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0207 0.0207
Echinococcus multilocularis RUN 0.0163 0.0427 0.0427
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0127 0.0127
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.0365 0.3029
Onchocerca volvulus 0.0083 0.019 0.0886
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0009 0.0018
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0068 0.0149 0.0149
Loa Loa (eye worm) beta-tubulin 0.1695 0.4948 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0076 0.017 0.0344
Schistosoma mansoni lamin 0.0085 0.0197 0.0311
Brugia malayi hypothetical protein 0.0163 0.0427 0.0864
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0039 0.0069
Trypanosoma brucei tubulin gamma chain 0.0967 0.2802 0.5663
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0034 0.0149
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.007
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0227 0.0616 0.5134
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0011 0.0023
Onchocerca volvulus 0.006 0.0125 0.0578
Trypanosoma brucei epsilon tubulin 0.0967 0.2801 0.5661
Brugia malayi MH2 domain containing protein 0.0042 0.0072 0.0145
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0207 0.0418
Loa Loa (eye worm) hypothetical protein 0.0246 0.0672 0.1357
Brugia malayi Thioredoxin reductase 0.0099 0.024 0.0485
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0651 0.1868 0.1868
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0134 0.0212
Brugia malayi nuclear receptor RXR 0.003 0.0034 0.0069
Echinococcus multilocularis lamin dm0 0.0085 0.0197 0.0197
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0047 0.0087 0.0137
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0048 0.0098
Schistosoma mansoni tubulin subunit alpha 0.1292 0.376 0.5931
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0015 0.0088
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0142 0.0224
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0068 0.0149 0.0234
Echinococcus multilocularis regulator of G protein signaling 0.0044 0.0078 0.0078
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0095 0.0228 0.046
Plasmodium falciparum tubulin delta chain, putative 0.0423 0.1194 0.2406
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0288 0.0454
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0044 0.0089
Echinococcus granulosus beta tubulin 0.1695 0.4948 0.7805
Loa Loa (eye worm) hypothetical protein 0.0378 0.1063 0.2148
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0104 0.0209
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0073
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0034 0.0149
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0068 0.0149 0.0149
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0011 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0115 0.0232
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0034 0.0054
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0451 0.1277 0.2581
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0288 0.0581
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.006 0.0125 0.0253
Echinococcus multilocularis geminin 0.0879 0.2541 0.2541
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0098 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0068 0.0149 0.03
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0011 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0098 0.0199
Leishmania major p-glycoprotein 0.0022 0.0013 0.0015
Schistosoma mansoni tubulin subunit beta 0.1695 0.4948 0.7805
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0156 0.0315
Schistosoma mansoni Smad4 0.0019 0.0003 0.0004
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0034 0.0069
Toxoplasma gondii protease inhibitor PI2 0.006 0.0125 0.0253
Brugia malayi hypothetical protein 0.0187 0.0498 0.1006
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0107 0.0262 0.052
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0068 0.0068
Brugia malayi TAZ zinc finger family protein 0.02 0.0538 0.1087
Onchocerca volvulus 0.0085 0.0197 0.0918
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0034 0.0069
Schistosoma mansoni nuclear hormone receptor 0.0068 0.0149 0.0234
Giardia lamblia Sgs1 DNA helicase, putative 0.003 0.0035 0.006
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0107 0.0262 0.0529
Loa Loa (eye worm) hypothetical protein 0.0205 0.0552 0.1116
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0183 0.0361
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0011 0.0055
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0006 0.0012
Trichomonas vaginalis tubulin gamma chain, putative 0.0423 0.1194 0.2413
Loa Loa (eye worm) hypothetical protein 0.0022 0.0012 0.0024
Trypanosoma brucei zeta tubulin, putative 0.0717 0.2063 0.4169
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0068 0.0149 0.03
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.003 0.0035 0.0035
Echinococcus granulosus transcription factor Dp 1 0.004 0.0064 0.0101
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0011 0.0055
Schistosoma mansoni patched 1 0.0088 0.0207 0.0326
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0035 0.007
Leishmania major hypothetical protein, conserved 0.0106 0.0259 0.0515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0156 0.0315
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0039 0.0061 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0068 0.0149 0.03
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0044 0.0079
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0044 0.0089
Echinococcus granulosus lipoxygenase domain containing protein 0.0163 0.0427 0.0674
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0035 0.007
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0079
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0013 0.0025
Brugia malayi CHE-14 protein 0.0088 0.0207 0.0418
Onchocerca volvulus 0.0737 0.2122 1
Schistosoma mansoni hypothetical protein 0.0085 0.0197 0.0311
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0076
Echinococcus granulosus Tubulin alpha 1 chain 0.1292 0.376 0.5931
Brugia malayi A-kinase anchor protein 10, precursor 0.0044 0.0078 0.0158
Brugia malayi Pre-SET motif family protein 0.0095 0.0226 0.0457
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.006 0.0125 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0068 0.0149 0.03
Brugia malayi Tubulin alpha-2 chain 0.1292 0.376 0.7599
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.0081 0.0164
Schistosoma mansoni smad 0.0019 0.0003 0.0004
Schistosoma mansoni tubulin subunit beta 0.1695 0.4948 0.7805
Loa Loa (eye worm) tubulin gamma chain 0.0967 0.2802 0.5663
Loa Loa (eye worm) steroid hormone receptor 0.0068 0.0149 0.03
Echinococcus granulosus tubulin alpha chain 0.1292 0.376 0.5931
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0044 0.0329
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0078 0.0158
Leishmania major beta tubulin 0.1695 0.4948 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0068 0.0149 0.0149
Chlamydia trachomatis endonuclease IV 0.008 0.0183 1
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0003 0.0003
Brugia malayi regulator of G-protein signaling egl-10 0.0044 0.0078 0.0158
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0022 0.0034
Giardia lamblia GTOR 0.0095 0.0228 0.0451
Brugia malayi tailless protein 0.003 0.0034 0.0069
Onchocerca volvulus 0.0204 0.0548 0.2571
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0078 0.0123
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.006 0.0095
Loa Loa (eye worm) hypothetical protein 0.0068 0.0149 0.03
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0107 0.0262 0.0529
Leishmania major gamma-tubulin 0.0967 0.2802 0.5659
Schistosoma mansoni hypothetical protein 0.0085 0.0197 0.0311
Brugia malayi Tubulin beta chain 0.0516 0.1471 0.2972
Brugia malayi prostaglandin transporter 0.0088 0.0208 0.042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Echinococcus granulosus microtubule associated protein 2 0.2166 0.6339 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0083
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0149 0.0292
Schistosoma mansoni aryl hydrocarbon receptor 0.0204 0.055 0.0868
Brugia malayi hypothetical protein 0.003 0.0034 0.0069
Loa Loa (eye worm) hypothetical protein 0.0044 0.0078 0.0158
Brugia malayi MH2 domain containing protein 0.0042 0.0072 0.0145
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.1292 0.376 0.7599
Loa Loa (eye worm) hypothetical protein 0.0068 0.0149 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0228 0.046
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0011 0.0055
Trichomonas vaginalis tubulin, putative 0.0451 0.1278 0.2584
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0142 0.0287
Echinococcus multilocularis FTZ F1 alpha 0.0068 0.0149 0.0149
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0095 0.0226 0.0457
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0034 0.0054
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0423 0.1194 0.2413
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0079
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0035 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0104 0.0209
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.019 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.006 0.0122
Echinococcus granulosus CREB binding protein 0.02 0.0538 0.0849
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0053 0.0104 0.0209
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.0013 0.0064
Trypanosoma cruzi epsilon tubulin, putative 0.0967 0.2801 0.5661
Leishmania major beta tubulin 0.1695 0.4948 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0124
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0078 0.0123
Entamoeba histolytica hypothetical protein 0.0044 0.0078 0.0158
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.006 0.0122
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Schistosoma mansoni tubulin subunit alpha 0.1292 0.376 0.5931
Brugia malayi MH1 domain containing protein 0.0023 0.0016 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0262 0.0529
Loa Loa (eye worm) tubulin alpha-3 chain 0.0776 0.2236 0.4519
Plasmodium vivax tubulin alpha chain, putative 0.1292 0.376 0.7596
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0048 0.0098
Onchocerca volvulus Huntingtin homolog 0.0378 0.1063 0.5002
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0081 0.0128
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0043 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0068 0.0149 0.03
Brugia malayi isocitrate dehydrogenase 0.0033 0.0044 0.0089
Echinococcus granulosus RUN 0.0163 0.0427 0.0674
Leishmania major delta tubulin, putative 0.0599 0.1714 0.3457
Brugia malayi Tubulin alpha chain 0.0423 0.1194 0.2413
Trypanosoma cruzi cytochrome P450, putative 0.0067 0.0144 0.0291
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0048 0.0098
Schistosoma mansoni multidrug resistance protein 0.0022 0.0013 0.002
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0073 0.0148
Entamoeba histolytica tubulin family protein 0.1695 0.4948 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0163 0.0427 0.0427
Trypanosoma brucei trypanothione reductase 0.0099 0.024 0.0485
Brugia malayi phosphofructokinase 0.0115 0.0288 0.0581
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0134 0.1087
Trichomonas vaginalis tubulin beta chain, putative 0.0516 0.1471 0.2972
Schistosoma mansoni cellular tumor antigen P53 0.0205 0.0551 0.0869
Loa Loa (eye worm) tubulin alpha chain 0.1292 0.376 0.7599
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0005 0.001
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.006 0.0125 0.0253
Trypanosoma brucei beta tubulin 0.1695 0.4948 1
Schistosoma mansoni thyroid hormone receptor 0.0068 0.0149 0.0234
Mycobacterium tuberculosis Probable reductase 0.0227 0.0616 0.5134
Brugia malayi ecdysteroid receptor 0.0068 0.0149 0.03
Loa Loa (eye worm) CBP-B 0.0139 0.0357 0.0722
Onchocerca volvulus 0.0163 0.0427 0.2004
Loa Loa (eye worm) BEN-1 protein 0.1695 0.4948 1
Trichomonas vaginalis tubulin beta chain, putative 0.1292 0.376 0.7599
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Schistosoma mansoni multidrug resistance protein 0.0022 0.0013 0.002
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0068 0.0149 0.03
Schistosoma mansoni RAR-like nuclear receptor 0.0068 0.0149 0.0234
Echinococcus granulosus tubulin alpha chain 0.1292 0.376 0.5931
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0078 0.0123
Brugia malayi hypoxia-induced factor 1 0.0632 0.1813 0.3665
Trypanosoma brucei beta tubulin 0.1695 0.4948 1
Giardia lamblia Alpha-tubulin 0.1292 0.376 0.7596
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0082 0.0129
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0124
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0011 0.0013
Echinococcus granulosus Niemann Pick C1 protein 0.0205 0.0552 0.0871
Loa Loa (eye worm) hypothetical protein 0.0252 0.0691 0.1396
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.017 0.0344
Echinococcus granulosus follistatin 0.006 0.0125 0.0197
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0061 0.0124
Onchocerca volvulus 0.0088 0.0208 0.0969
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0054 0.0106 0.0215
Brugia malayi jmjC domain containing protein 0.0061 0.0127 0.0257
Plasmodium vivax tubulin gamma chain, putative 0.0967 0.2802 0.5659
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0205 0.0552 0.1116
Trichomonas vaginalis tubulin gamma chain, putative 0.0967 0.2802 0.5663
Plasmodium falciparum tubulin epsilon chain, putative 0.0967 0.2801 0.5656
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0068 0.0149 0.03
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0011 0.002
Echinococcus granulosus Tubulin alpha 1 chain 0.1292 0.376 0.5931
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Trypanosoma cruzi zeta tubulin, putative 0.0717 0.2063 0.4169
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Trypanosoma brucei epsilon tubulin 0.0939 0.2718 0.5493
Brugia malayi Cytochrome P450 family protein 0.0067 0.0144 0.0291
Echinococcus granulosus CREB binding protein 0.0033 0.0044 0.0069
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.0013 0.0025
Schistosoma mansoni hypothetical protein 0.0163 0.0427 0.0674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0083
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0191 0.051 0.0804
Echinococcus multilocularis lipoxygenase domain containing protein 0.0163 0.0427 0.0427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0083
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0089 0.021 0.0332
Brugia malayi Cytochrome P450 family protein 0.0067 0.0144 0.0291
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0011 0.0055
Onchocerca volvulus 0.003 0.0034 0.0149
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0044 0.0089
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0013 0.0025
Echinococcus granulosus mitogen activated protein kinase 3 0.0107 0.0262 0.0413
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0011 0.0055
Brugia malayi nuclear receptor RXR 0.0039 0.0061 0.0124
Schistosoma mansoni hypothetical protein 0.0268 0.0738 0.1163
Trichomonas vaginalis tubulin, putative 0.1695 0.4948 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0044 0.0078 0.0078
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0064 0.0064
Echinococcus granulosus tubulin alpha 1C chain 0.1292 0.376 0.5931
Loa Loa (eye worm) tubulin alpha 2 0.0869 0.2513 0.5078
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.006 0.0122
Echinococcus granulosus ecdysone induced protein 78C 0.0068 0.0149 0.0234
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0072 0.0072
Brugia malayi MH1 domain containing protein 0.0042 0.0072 0.0145
Toxoplasma gondii beta-tubulin, putative 0.1695 0.4948 1
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.0365 0.3029
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0039 0.0069
Brugia malayi regulator of G-protein signaling rgs-7 0.0044 0.0078 0.0158
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0044 0.0089
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0078 0.0078
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0869 0.2513 0.5078
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0013 0.002
Echinococcus granulosus tubulin alpha chain 0.1292 0.376 0.5931
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0288 0.0581
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0142 0.0224
Schistosoma mansoni smad1 5 8 and 0.0042 0.0072 0.0113
Loa Loa (eye worm) tubulin beta-2A chain 0.1695 0.4948 1
Echinococcus granulosus tubulin gamma 1 chain 0.0967 0.2802 0.442
Echinococcus granulosus regulator of G protein signaling 3 0.0044 0.0078 0.0123
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0227 0.0616 0.5134
Echinococcus granulosus survival motor neuron protein 1 0.0246 0.0672 0.1059
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0068 0.0149 0.0234
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Loa Loa (eye worm) hypothetical protein 0.0068 0.0149 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0099 0.0199
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0068 0.0107
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0068 0.0149 0.03
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0124
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0053 0.0104 0.0163
Loa Loa (eye worm) pax transcription factor protein 2 0.025 0.0684 0.1383
Schistosoma mansoni DNA helicase recq1 0.003 0.0035 0.0055
Entamoeba histolytica hypothetical protein 0.0023 0.0015 0.0031
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0262 0.0529
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0025
Echinococcus multilocularis neuropeptide receptor A26 0.0968 0.2802 0.2802
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0015 0.0088
Mycobacterium leprae putative cytochrome p450 0.0022 0.0011 0.002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0034 0.0034
Echinococcus granulosus bloom syndrome protein 0.0043 0.0073 0.0116
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0068 0.0149 0.0149
Loa Loa (eye worm) tubulin alpha 2 0.0869 0.2513 0.5078
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.0013 0.0025
Leishmania major cytochrome p450-like protein 0.0067 0.0144 0.0282
Brugia malayi multidrug resistance protein 3 0.0022 0.0013 0.0025
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0078 0.0123
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0134 0.1087
Trypanosoma brucei beta tubulin 0.1695 0.4948 1
Onchocerca volvulus Putative organic anion transporter 0.0088 0.0208 0.0969
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.019 0.03
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0034 0.0034
Trichomonas vaginalis helicase, putative 0.002 0.0006 0.0012
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0011 0.0055
Trypanosoma brucei protein kinase, putative 0.0107 0.0262 0.0529
Leishmania major beta tubulin 0.1695 0.4948 1
Plasmodium falciparum glutathione reductase 0.0099 0.024 0.0476
Mycobacterium ulcerans cell division protein FtsZ 0.0423 0.1194 1
Schistosoma mansoni tubulin subunit beta 0.1695 0.4948 0.7805
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0068 0.0149 0.0234
Echinococcus granulosus tubulin alpha chain 0.1292 0.376 0.5931
Echinococcus granulosus tubulin epsilon chain 0.0967 0.2801 0.4418
Loa Loa (eye worm) hypothetical protein 0.008 0.0183 0.0371
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0083
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0011 0.0055
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0039 0.0079
Entamoeba histolytica tubulin family protein 0.1695 0.4948 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0044 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0034 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0011 0.0055
Leishmania major beta tubulin 0.1695 0.4948 1
Plasmodium vivax delta tubulin, putative 0.0423 0.1194 0.2406
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0187 0.0498 0.0498
Echinococcus multilocularis tubulin subunit TubB 0.1292 0.376 0.376
Echinococcus multilocularis mitogen activated protein kinase 0.0107 0.0262 0.0262
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0011 0.0055
Schistosoma mansoni polycystin 1-related 0.0163 0.0427 0.0674
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.006 0.0095
Echinococcus multilocularis Tubulin alpha 1 chain 0.1292 0.376 0.376
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0079
Echinococcus granulosus ATP dependent DNA helicase Q5 0.003 0.0035 0.0055
Leishmania major cytochrome p450-like protein 0.0022 0.0011 0.0013
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0044 0.0044
Echinococcus multilocularis Niemann Pick C1 protein 0.0293 0.0812 0.0812
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0022 0.0045
Trichomonas vaginalis tubulin gamma chain, putative 0.0967 0.2801 0.5661
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0226 0.0356
Leishmania major protein kinase, putative 0.0054 0.0106 0.0205
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0068 0.0149 0.0234
Echinococcus multilocularis expressed protein 0.006 0.0125 0.0125
Giardia lamblia Kinase, CMGC MAPK 0.0107 0.0262 0.052
Loa Loa (eye worm) phosphatidylinositol 3 0.0095 0.0228 0.046
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0262 0.0529
Echinococcus granulosus lamin dm0 0.0085 0.0197 0.0311
Echinococcus granulosus tubulin subunit TubB 0.1292 0.376 0.5931
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0113 0.0228
Brugia malayi PXA domain containing protein 0.0044 0.0078 0.0158
Plasmodium falciparum thioredoxin reductase 0.0034 0.0048 0.0088
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0048 0.0088
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.0013 0.0015
Schistosoma mansoni transcription factor LCR-F1 0.0187 0.0498 0.0785
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Echinococcus granulosus FTZ F1 alpha 0.0068 0.0149 0.0234
Loa Loa (eye worm) hypothetical protein 0.0068 0.0149 0.03
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0039 0.0079
Onchocerca volvulus 0.005 0.0095 0.0434
Mycobacterium tuberculosis Probable oxidoreductase 0.0252 0.069 0.5762
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0095 0.0228 0.046
Loa Loa (eye worm) hypothetical protein 0.0378 0.1063 0.2148
Schistosoma mansoni intermediate filament proteins 0.0085 0.0197 0.0311
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0259 0.0712 0.0712
Echinococcus granulosus regulator of G protein signaling 7 0.0044 0.0078 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0068 0.0149 0.03
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0072 0.0145
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0005 0.001
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0079
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0072 0.0072
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0013 0.002
Entamoeba histolytica P-glycoprotein-1 0.0022 0.0013 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0115 0.0232
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0088 0.0208 0.042
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0227 0.0616 0.5134
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0011 0.0055
Mycobacterium ulcerans putative regulatory protein 0.0151 0.0393 0.3265
Loa Loa (eye worm) hypothetical protein 0.0044 0.0078 0.0158
Schistosoma mansoni nuclear receptor 0.003 0.0034 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0011 0.0055
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0053 0.0104 0.02
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0013 0.002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0068 0.0149 0.03
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0079
Plasmodium falciparum tubulin beta chain 0.1695 0.4948 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0068 0.0149 0.0234
Brugia malayi hypothetical protein 0.0163 0.0427 0.0864
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0113 0.0228
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0022 0.0012 0.0019
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0013 0.0025
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0043 0.0086
Echinococcus granulosus thioredoxin glutathione reductase 0.0099 0.024 0.0379
Toxoplasma gondii target of rapamycin (TOR), putative 0.0071 0.0156 0.0315
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0134 0.0212
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0048 0.0088
Plasmodium falciparum tubulin gamma chain 0.0967 0.2802 0.5659
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0045 0.0081 0.0164
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0012
Brugia malayi Doublecortin family protein 0.0163 0.0427 0.0864
Echinococcus multilocularis thioredoxin glutathione reductase 0.0099 0.024 0.024
Loa Loa (eye worm) BEN-1 protein 0.1695 0.4948 1
Onchocerca volvulus Bile acid receptor homolog 0.0068 0.0149 0.0689
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0183 0.0361
Giardia lamblia Beta tubulin 0.1695 0.4948 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0088 0.0208 0.042
Echinococcus granulosus beta-adrenergic receptor kinase 0.0045 0.0081 0.0128
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0072 0.0113
Brugia malayi CXXC zinc finger family protein 0.0088 0.0208 0.042
Schistosoma mansoni smad 0.0042 0.0072 0.0113
Loa Loa (eye worm) hypothetical protein 0.0088 0.0208 0.042
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0022 0.0043
Echinococcus granulosus tubulin beta 4A class IVa 0.1695 0.4948 0.7805
Schistosoma mansoni tubulin subunit alpha 0.1292 0.376 0.5931
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0038 0.0059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0034 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.019 0.019
Echinococcus granulosus tubulin alpha 3 chain 0.1292 0.376 0.5931
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0107 0.0262 0.052
Trichomonas vaginalis tubulin, putative 0.0516 0.1471 0.2972
Toxoplasma gondii histone lysine methyltransferase SET1 0.0174 0.0461 0.0932
Echinococcus granulosus tumor protein p63 0.1398 0.4073 0.6425
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0006 0.0012
Brugia malayi jmjC domain containing protein 0.0066 0.0142 0.0287
Brugia malayi Cytochrome P450 family protein 0.0022 0.0011 0.0023
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.0013 0.0025
Onchocerca volvulus Protein ultraspiracle homolog 0.0068 0.0149 0.0689
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.006 0.006
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0044 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Echinococcus multilocularis Tubulin beta 2C chain 0.1695 0.4948 0.4948
Echinococcus multilocularis follistatin 0.006 0.0125 0.0125
Schistosoma mansoni multidrug resistance protein 0.0022 0.0013 0.002
Echinococcus granulosus beta tubulin 0.1695 0.4948 0.7805
Onchocerca volvulus 0.0088 0.0208 0.0969
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0048
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0095 0.0228 0.0451
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0011 0.0055
Loa Loa (eye worm) DR-78 0.003 0.0034 0.0069
Loa Loa (eye worm) alpha-tubulin 0.1292 0.376 0.7599
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0034 0.0034
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0939 0.2718 0.5493
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.0365 0.3004
Echinococcus multilocularis smad 0.0042 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Onchocerca volvulus Putative organic anion transporter 0.0088 0.0208 0.0969
Loa Loa (eye worm) hypothetical protein 0.0088 0.0208 0.042
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0262 0.0413
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0124
Schistosoma mansoni nuclear hormone receptor 0.003 0.0034 0.0054
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0095 0.0228 0.0451
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0068 0.0149 0.03
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0011 0.0023
Brugia malayi hypothetical protein 0.0068 0.0149 0.03
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0011 0.0055
Plasmodium falciparum multidrug resistance protein 1 0.0022 0.0013 0.0015
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0173 0.0173
Echinococcus multilocularis protein dispatched 1 0.01 0.0243 0.0243
Brugia malayi hypothetical protein 0.0044 0.0078 0.0158
Toxoplasma gondii tubulin, putative 0.0028 0.003 0.006
Brugia malayi hypothetical protein 0.0039 0.0061 0.0124
Loa Loa (eye worm) raf kinase 0.0046 0.0082 0.0166
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0015 0.0088
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0012 0.0012
Onchocerca volvulus Huntingtin homolog 0.0378 0.1063 0.5002
Echinococcus granulosus neuropeptide s receptor 0.0968 0.2802 0.4421
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0053 0.0104 0.5332
Echinococcus multilocularis agrin 0.006 0.0125 0.0125
Entamoeba histolytica tubulin alpha-1 chain 0.1292 0.376 0.7599
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0015 0.0031
Loa Loa (eye worm) hypothetical protein 0.0083 0.019 0.0385
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0041 0.0083
Echinococcus granulosus Niemann Pick C1 protein 0.0293 0.0812 0.1281
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0099 0.0199
Schistosoma mansoni cpg binding protein 0.0088 0.0208 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0078 0.0158
Brugia malayi Nuclear hormone receptor E75 0.003 0.0034 0.0069
Loa Loa (eye worm) cytochrome P450 0.0022 0.0011 0.0023
Mycobacterium leprae Possible regulatory protein 0.0053 0.0104 0.0798
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0012
Leishmania major beta tubulin 0.1695 0.4948 1
Echinococcus granulosus peroxisome assembly protein 26 0.1292 0.376 0.5931
Onchocerca volvulus 0.0163 0.0427 0.2004
Onchocerca volvulus 0.0095 0.0226 0.1054
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Brugia malayi Tubulin alpha-2 chain 0.1292 0.376 0.7599
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0262 0.0529
Schistosoma mansoni tubulin subunit beta 0.0423 0.1194 0.1884
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0009 0.003
Echinococcus granulosus raf serine:threonine protein kinase 0.0046 0.0082 0.0129
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0034 0.0054
Echinococcus granulosus Tubulin beta 2C chain 0.1695 0.4948 0.7805
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0776 0.2236 0.4519
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Leishmania major beta tubulin 0.1695 0.4948 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0053 0.0104 0.0209
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0068 0.0149 0.0149
Schistosoma mansoni lipoxygenase 0.0651 0.1868 0.2947
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.0043 0.0086
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0015 0.0021
Echinococcus granulosus axis inhibition protein axin 0.0044 0.0078 0.0123
Entamoeba histolytica P-glycoprotein-5 0.0022 0.0013 0.0025
Echinococcus multilocularis Tubulin beta 2C chain 0.1695 0.4948 0.4948
Brugia malayi 6-phosphofructokinase 0.0116 0.0288 0.0583
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0099 0.024 0.1977
Brugia malayi hypothetical protein 0.003 0.0034 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0135 0.0273
Loa Loa (eye worm) PXA domain-containing protein 0.0044 0.0078 0.0158
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0127 0.0201
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.006 0.0122
Leishmania major beta tubulin 0.1695 0.4948 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0053 0.0104 0.0209
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0648 0.1859 0.3757
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0011 0.0055
Trichomonas vaginalis tubulin beta chain, putative 0.1292 0.376 0.7599
Schistosoma mansoni agrin 0.006 0.0125 0.0197
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.000000014007 0.000000022094
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0011 0.0055
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.006 0.0125 0.0253
Onchocerca volvulus 0.0088 0.0208 0.0967
Echinococcus multilocularis beta tubulin 0.1695 0.4948 0.4948
Echinococcus granulosus expressed protein 0.0772 0.2226 0.3512
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0048 0.0098
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0068 0.0149 0.0234
Loa Loa (eye worm) thioredoxin reductase 0.0099 0.024 0.0485
Brugia malayi hypothetical protein 0.0039 0.0061 0.0124
Leishmania major cytochrome p450-like protein 0.0022 0.0011 0.0013
Trichomonas vaginalis tubulin alpha chain, putative 0.1695 0.4948 1
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.008 0.0183 0.0371
Schistosoma mansoni jun-related protein 0.0211 0.0569 0.0897
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0022 0.0034
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0034 0.0054
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0149 0.0302
Loa Loa (eye worm) hypothetical protein 0.006 0.0125 0.0253
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0088 0.0208 0.0328
Echinococcus granulosus agrin 0.006 0.0125 0.0197
Loa Loa (eye worm) hypothetical protein 0.0088 0.0208 0.042
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Trichomonas vaginalis tubulin beta chain, putative 0.1695 0.4948 1
Echinococcus multilocularis tubulin alpha 1C chain 0.1292 0.376 0.376
Echinococcus multilocularis regulator of G protein signaling 7 0.0044 0.0078 0.0078
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0252 0.069 0.5762
Loa Loa (eye worm) ATP-dependent DNA helicase 0.003 0.0035 0.007
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.001 0.001
Brugia malayi tubulin alpha-2 chain 0.1292 0.376 0.7599
Schistosoma mansoni cpg binding protein 0.0093 0.0222 0.0351
Leishmania major beta tubulin 0.1695 0.4948 1
Trichomonas vaginalis tubulin, putative 0.0516 0.1471 0.2972
Loa Loa (eye worm) hypothetical protein 0.0088 0.0207 0.0418
Loa Loa (eye worm) hypothetical protein 0.0163 0.0427 0.0864
Loa Loa (eye worm) hypothetical protein 0.0044 0.0078 0.0158
Loa Loa (eye worm) hypothetical protein 0.0044 0.0078 0.0158
Brugia malayi intermediate filament protein 0.0085 0.0197 0.0399
Leishmania major beta tubulin 0.1695 0.4948 1
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0011 0.0055
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0044 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.017 0.0344
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0068 0.0149 0.0234
Echinococcus granulosus tubulin alpha 0.0939 0.2718 0.4287
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0005 0.001
Echinococcus granulosus intermediate filament protein 0.0085 0.0197 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0156 0.0315
Echinococcus multilocularis protein patched 0.0088 0.0207 0.0207
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0226 0.0457
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0005 0.001
Trichomonas vaginalis guanylate cyclase, putative 0.0053 0.0104 0.0209
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.006 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0078 0.0158
Brugia malayi MH1 domain containing protein 0.0042 0.0072 0.0145
Entamoeba histolytica hypothetical protein 0.0187 0.0498 0.1006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0068 0.0149 0.0149
Brugia malayi MH2 domain containing protein 0.062 0.1777 0.3591
Leishmania major epsilon tubulin, putative 0.0967 0.2801 0.5656
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0226 0.0356
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0095 0.0228 0.0228
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0068 0.0149 0.0689
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0073 0.0148
Brugia malayi Pax transcription factor protein 2 0.025 0.0684 0.1383
Toxoplasma gondii endonuclease IV APN 0.008 0.0183 0.0371
Trypanosoma cruzi target of rapamycin kinase 3 0.0076 0.017 0.0344
Echinococcus multilocularis Niemann Pick C1 protein 0.0205 0.0552 0.0552
Onchocerca volvulus 0.0085 0.0197 0.0918
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Schistosoma mansoni rab6-interacting 0.0163 0.0427 0.0674
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0053 0.0104 0.0209
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0015 0.0053
Echinococcus granulosus expressed conserved protein 0.0193 0.0516 0.0813
Plasmodium vivax SET domain protein, putative 0.0095 0.0226 0.0447
Brugia malayi MAP kinase sur-1 0.0107 0.0262 0.0529
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0073 0.0148
Trichomonas vaginalis adenylate cyclase, putative 0.0053 0.0104 0.0209
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0259 0.0524
Entamoeba histolytica tubulin gamma chain 0.0967 0.2802 0.5663
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0053 0.0104 0.0209
Trichomonas vaginalis guanylate cyclase, putative 0.0053 0.0104 0.0209
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0095 0.0228 0.0359
Brugia malayi Niemann-Pick C1 protein precursor 0.0205 0.0552 0.1116
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Echinococcus granulosus tubulin beta 1 chain 0.1695 0.4948 0.7805
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0088 0.0208 0.0208
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0226 0.0226
Echinococcus granulosus tubulin alpha 3 chain 0.1292 0.376 0.5931
Loa Loa (eye worm) hypothetical protein 0.0068 0.0149 0.03
Echinococcus multilocularis hypothetical protein 0.1292 0.376 0.376
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0094 0.0224 0.0453
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0095 0.0228 0.046
Loa Loa (eye worm) hypothetical protein 0.0068 0.0149 0.03
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0366
Echinococcus multilocularis tubulin alpha 1C chain 0.1292 0.376 0.376
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.006 0.0125 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0156 0.0315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.017 0.0344
Brugia malayi Nuclear hormone receptor-like 1 0.0068 0.0149 0.03
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0041 0.0073
Plasmodium vivax ataxin-2 like protein, putative 0.0106 0.0259 0.0515
Loa Loa (eye worm) hypothetical protein 0.0068 0.0149 0.03
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0045 0.0081 0.0164
Schistosoma mansoni smad1 5 8 and 0.0042 0.0072 0.0113
Brugia malayi Pre-SET motif family protein 0.0648 0.1859 0.3757
Brugia malayi photoreceptor-specific nuclear receptor 0.0068 0.0149 0.03
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0034 0.0069
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.003 0.0035 0.006
Loa Loa (eye worm) tubulin alpha chain 0.1292 0.376 0.7599
Echinococcus multilocularis tubulin gamma 1 chain 0.0967 0.2802 0.2802
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0044 0.0078 0.0123
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.006 0.0125 0.0253
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0262 0.0529
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0104 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0081 0.0128
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0078 0.0123
Echinococcus multilocularis microtubule associated protein 2 0.2166 0.6339 0.6339
Echinococcus granulosus Regulator of G protein signaling 20 0.0044 0.0078 0.0123
Echinococcus granulosus CREB binding protein 0.0124 0.0311 0.0491
Toxoplasma gondii alpha-tubulin I, putative 0.1292 0.376 0.7599
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0045 0.008 0.0161
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0083
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0011 0.0018
Brugia malayi cytochrome P450 0.0022 0.0011 0.0023
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0011 0.0023
Echinococcus multilocularis jun protein 0.0259 0.0712 0.0712
Echinococcus granulosus tubulin subunit beta 0.1695 0.4948 0.7805
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.008 0.0183 0.147
Schistosoma mansoni alpha tubulin 0.1292 0.376 0.5931
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0259 0.0524
Echinococcus granulosus Tubulin alpha 1 chain 0.1292 0.376 0.5931
Trichomonas vaginalis tubulin alpha chain, putative 0.0516 0.1471 0.2972
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0015 0.0021
Schistosoma mansoni survival motor neuron protein 0.005 0.0095 0.0149
Brugia malayi Regulator of G protein signaling domain containing protein 0.0044 0.0078 0.0158
Echinococcus multilocularis expressed conserved protein 0.0193 0.0516 0.0516
Plasmodium vivax multidrug resistance protein 1, putative 0.0022 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0025
Brugia malayi hypothetical protein 0.0044 0.0078 0.0158
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0288 0.0581
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.006 0.006
Mycobacterium ulcerans epimerase 0.0021 0.0009 0.0035
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0044 0.0078 0.0158
Schistosoma mansoni rab6-interacting 0.0163 0.0427 0.0674
Schistosoma mansoni single-minded 0.0204 0.055 0.0868
Echinococcus multilocularis tubulin alpha chain 0.1292 0.376 0.376
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0048 0.0366
Onchocerca volvulus Putative organic anion transporter 0.0088 0.0208 0.0969
Loa Loa (eye worm) RGS-3 protein 0.0044 0.0078 0.0158
Echinococcus multilocularis tubulin alpha 3 chain 0.1292 0.376 0.376
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0011 0.0055
Echinococcus granulosus mitogen activated protein kinase 0.0107 0.0262 0.0413
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0098
Treponema pallidum cell division protein FtsZ 0.0423 0.1194 1
Trypanosoma brucei beta tubulin 0.0939 0.2718 0.5493
Loa Loa (eye worm) hypothetical protein 0.0163 0.0427 0.0864
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0288 0.0581
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0228 0.046
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0078 0.0123
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0095 0.0228 0.046
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0011 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0129 0.0261
Schistosoma mansoni hypothetical protein 0.0022 0.0011 0.0018
Plasmodium vivax glutathione reductase, putative 0.0099 0.024 0.0476
Entamoeba histolytica tubulin alpha chain, putative 0.1292 0.376 0.7599
Trichomonas vaginalis tubulin beta chain, putative 0.1292 0.376 0.7599
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0012
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0035 0.007
Loa Loa (eye worm) agrin synaptic family protein 0.006 0.0125 0.0253
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0127 0.0201
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0013 0.002
Schistosoma mansoni hypothetical protein 0.005 0.0095 0.0149
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0078 0.0078
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0012
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0048 0.0098
Schistosoma mansoni Smad4 0.0042 0.0072 0.0113
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.006 0.0122
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0068 0.0149 0.0234
Giardia lamblia Delta tubulin 0.0423 0.1194 0.2406
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0252 0.069 0.5762
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0006 0.0012
Mycobacterium leprae cell division protein FtsZ 0.0423 0.1194 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Echinococcus granulosus Polycystic kidney disease protein 0.0163 0.0427 0.0674
Leishmania major trypanothione reductase 0.0099 0.024 0.0476
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0076
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0039 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0068 0.0149 0.03
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0041 0.0083
Trypanosoma brucei PAB1-binding protein , putative 0.0106 0.0259 0.0524
Schistosoma mansoni organic anion transporter 0.0088 0.0208 0.0328
Brugia malayi hypothetical protein 0.0088 0.0208 0.042
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0134 0.0271
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0128
Trichomonas vaginalis abcb9, putative 0.0022 0.0013 0.0025
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0149 0.0302
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0088 0.0208 0.0208
Brugia malayi Smad1 0.0042 0.0072 0.0145
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0011 0.0055
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0015 0.0031
Echinococcus multilocularis tubulin alpha 3 chain 0.1292 0.376 0.376
Echinococcus multilocularis raf serine:threonine protein kinase 0.0046 0.0082 0.0082
Loa Loa (eye worm) Smad1 0.0042 0.0072 0.0145
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0098
Loa Loa (eye worm) hypothetical protein 0.0686 0.197 0.3982
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Echinococcus multilocularis Tubulin alpha 1 chain 0.1292 0.376 0.376
Toxoplasma gondii alpha tubulin TUBA1 0.1292 0.376 0.7599
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0044 0.0079
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0078 0.0123
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0226 0.0356
Plasmodium vivax tubulin beta chain, putative 0.1695 0.4948 1
Leishmania major beta tubulin 0.1695 0.4948 1
Trypanosoma brucei zeta tubulin 0.0717 0.2063 0.4169
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0288 0.0288
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0144 0.0291
Giardia lamblia Alpha-tubulin 0.1292 0.376 0.7596
Echinococcus granulosus tubulin alpha chain 0.1292 0.376 0.5931
Plasmodium falciparum glutathione reductase 0.0034 0.0048 0.0088
Echinococcus granulosus tubulin delta chain 0.0423 0.1194 0.1884
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0067 0.0144 0.1171
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0011 0.0055
Schistosoma mansoni hypothetical protein 0.0187 0.0498 0.0785
Echinococcus multilocularis tubulin subunit beta 0.1695 0.4948 0.4948
Brugia malayi bZIP transcription factor family protein 0.0259 0.0712 0.1439
Brugia malayi Intermediate filament tail domain containing protein 0.0085 0.0197 0.0399
Entamoeba histolytica hypothetical protein 0.0187 0.0498 0.1006
Trichomonas vaginalis conserved hypothetical protein 0.0423 0.1194 0.2413
Echinococcus granulosus aryl hydrocarbon receptor 0.0053 0.0104 0.0163
Echinococcus multilocularis tubulin delta chain 0.0423 0.1194 0.1194
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0098
Brugia malayi Raf kinase 0.0046 0.0082 0.0166
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0288 0.0572
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0013 0.002
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.019 0.0385
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0061 0.0124
Echinococcus multilocularis thyroid hormone receptor alpha 0.0068 0.0149 0.0149
Trypanosoma cruzi alpha tubulin, putative 0.1292 0.376 0.7599
Echinococcus granulosus Tubulin beta 2C chain 0.1695 0.4948 0.7805
Echinococcus multilocularis Tubulin beta 2C chain 0.1695 0.4948 0.4948
Loa Loa (eye worm) tubulin beta-4 chain 0.1695 0.4948 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.003 0.0034 0.0054
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0083
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0134 0.0262
Loa Loa (eye worm) hypothetical protein 0.0044 0.0078 0.0158
Schistosoma mansoni tubulin subunit delta 0.0423 0.1194 0.1884
Brugia malayi sodium-independent organic anion transporter family protein 0.0088 0.0208 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0156 0.0315
Trypanosoma cruzi cytochrome P450, putative 0.0067 0.0144 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0011 0.0055
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0068 0.0149 0.0234
Loa Loa (eye worm) alpha-tubulin 0.1292 0.376 0.7599
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.006 0.0095
Brugia malayi hypothetical protein 0.0686 0.197 0.3982
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.006 0.0112
Brugia malayi cytoplasmic intermediate filament protein 0.0045 0.0081 0.0164
Brugia malayi Tubulin beta-1 chain 0.1695 0.4948 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Echinococcus granulosus Smad4 0.0042 0.0072 0.0113
Echinococcus multilocularis axis inhibition protein axin 0.0044 0.0078 0.0078
Trypanosoma brucei cytochrome P450, putative 0.0067 0.0144 0.0291
Schistosoma mansoni thyroid hormone receptor 0.0068 0.0149 0.0234
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.017 0.0344
Brugia malayi PAS domain containing protein 0.0204 0.055 0.1112
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0015 0.0088
Loa Loa (eye worm) hypothetical protein 0.0041 0.0068 0.0137
Trypanosoma cruzi zeta tubulin, putative 0.0717 0.2063 0.4169
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.006 0.0122
Schistosoma mansoni microtubule-associated protein tau 0.2166 0.6339 1
Trichomonas vaginalis tubulin beta chain, putative 0.1292 0.376 0.7599
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.006 0.0125 0.0253
Brugia malayi Cell division protein ftsZ 0.0423 0.1194 0.2413
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0011 0.0055
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0011 0.0055
Trichomonas vaginalis tubulin alpha chain, putative 0.0516 0.1471 0.2972
Brugia malayi 6-phosphofructokinase 0.0115 0.0288 0.0581
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0021 0.0042
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.0013 0.0025
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0048 0.0098
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0095 0.0228 0.046
Schistosoma mansoni alpha tubulin 0.1292 0.376 0.5931
Schistosoma mansoni ap endonuclease 0.002 0.0005 0.0008
Echinococcus multilocularis tubulin alpha chain 0.1292 0.376 0.376
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0022 0.0013 0.0025
Schistosoma mansoni hypothetical protein 0.0085 0.0197 0.0311
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0005 0.001
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0207 0.0326
Schistosoma mansoni tubulin subunit beta 0.1695 0.4948 0.7805
Loa Loa (eye worm) hypothetical protein 0.006 0.0125 0.0253
Brugia malayi PXA domain containing protein 0.0044 0.0078 0.0158
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0095 0.0226 0.0356
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0072 0.0113
Trypanosoma brucei tubulin delta chain 0.0599 0.1714 0.3464
Brugia malayi Tubulin beta chain 0.0423 0.1194 0.2413
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0128
Onchocerca volvulus 0.0088 0.0208 0.0969
Toxoplasma gondii thioredoxin reductase 0.0099 0.024 0.0485
Echinococcus multilocularis neuropeptide s receptor 0.0968 0.2802 0.2802
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0124
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0034 0.0054
Loa Loa (eye worm) transcription factor SMAD2 0.062 0.1777 0.3591
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0078 0.0158
Echinococcus multilocularis CREB binding protein 0.0033 0.0044 0.0044
Echinococcus multilocularis Polycystic kidney disease protein 0.0163 0.0427 0.0427
Trypanosoma cruzi tubulin gamma chain 0.0967 0.2802 0.5663
Echinococcus granulosus lipoxygenase domain containing protein 0.0163 0.0427 0.0674
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0011 0.0055
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0039 0.0079
Schistosoma mansoni organic anion transporter 0.0088 0.0208 0.0328
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0072 0.0113
Echinococcus granulosus cpg binding protein 0.0093 0.0222 0.0351
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0015 0.0021
Loa Loa (eye worm) tubulin beta-1 chain 0.1695 0.4948 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0134 0.0134
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0022 0.0022
Schistosoma mansoni DNA helicase recq5 0.003 0.0035 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0068 0.0149 0.03
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.0259 0.0515
Echinococcus multilocularis musashi 0.0085 0.0197 0.0197
Brugia malayi beta-tubulin, identical 0.1695 0.4948 1
Brugia malayi Steroid receptor seven-up type 2 0.0068 0.0149 0.03
Echinococcus granulosus lamin 0.0085 0.0197 0.0311
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0288 0.0581
Brugia malayi MH2 domain containing protein 0.0019 0.0003 0.0005
Plasmodium falciparum LCCL domain-containing protein 0.0163 0.0427 0.0855
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Echinococcus multilocularis tubulin beta 1 chain 0.1695 0.4948 0.4948
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0149 0.0235
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0068 0.0149 0.03
Echinococcus multilocularis beta adrenergic receptor kinase 0.0045 0.0081 0.0081
Schistosoma mansoni smad1 5 8 and 0.0042 0.0072 0.0113
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0011 0.0055
Loa Loa (eye worm) hypothetical protein 0.0205 0.0551 0.1113
Echinococcus multilocularis tubulin alpha chain 0.1292 0.376 0.376
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0149 0.0302
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0048 0.0366
Schistosoma mansoni coup transcription factor 0.0068 0.0149 0.0234
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0288 0.0581
Trypanosoma brucei beta tubulin 0.1695 0.4948 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0651 0.1868 0.2947
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0011 0.0055
Schistosoma mansoni CREB-binding protein 2 0.02 0.0538 0.0849
Trypanosoma cruzi tubulin delta chain 0.0599 0.1714 0.3464
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0068 0.0149 0.03
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0044 0.0078 0.0123
Giardia lamblia Beta tubulin 0.1695 0.4948 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0125 0.0253
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.006 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0011 0.0055
Loa Loa (eye worm) glutathione reductase 0.0099 0.024 0.0485
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0226 0.0356
Brugia malayi nuclear hormone receptor 0.0068 0.0149 0.03
Onchocerca volvulus 0.0516 0.1471 0.6925
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0047 0.0087 0.0087
Toxoplasma gondii beta tubulin 0.1695 0.4948 1
Echinococcus multilocularis Tubulin beta 2C chain 0.1695 0.4948 0.4948
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.006 0.0125 0.0253
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0078 0.0078
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0034 0.0069
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0068 0.0149 0.03
Schistosoma mansoni regulator of G protein signaling 0.0044 0.0078 0.0123
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0288 0.0581
Plasmodium falciparum thioredoxin reductase 0.0099 0.024 0.0476
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0008
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0098 0.0199
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0134 0.1087
Trypanosoma cruzi beta tubulin, putative 0.1695 0.4948 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0041 0.0083
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0095 0.0228 0.046
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0288 0.0581
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0018
Trypanosoma cruzi tubulin delta chain 0.0599 0.1714 0.3464
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0065 0.0122
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0044 0.0078 0.0123
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.006 0.0095
Echinococcus multilocularis tubulin alpha chain 0.1292 0.376 0.376
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0048 0.0098
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0015 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0099 0.0199
Entamoeba histolytica hypothetical protein 0.0044 0.0078 0.0158
Brugia malayi glutathione reductase 0.0099 0.024 0.0485
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0011 0.0055
Onchocerca volvulus 0.0022 0.0013 0.0047
Schistosoma mansoni cpg binding protein 0.0093 0.0222 0.0351
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0107 0.0262 0.0529
Onchocerca volvulus 0.0053 0.0104 0.0477
Mycobacterium tuberculosis Cell division protein FtsZ 0.0423 0.1194 1
Schistosoma mansoni tubulin subunit beta 0.1695 0.4948 0.7805
Loa Loa (eye worm) hypothetical protein 0.0085 0.0197 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.0423 0.1194 0.2413
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0095 0.0228 0.046
Echinococcus multilocularis peroxisome assembly protein 26 0.1292 0.376 0.376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0099 0.0199
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0208 0.042
Echinococcus multilocularis expressed protein 0.0772 0.2226 0.2226
Echinococcus granulosus tubulin alpha 1C chain 0.1292 0.376 0.5931
Loa Loa (eye worm) hypothetical protein 0.0053 0.0104 0.0209
Leishmania major beta tubulin 0.1695 0.4948 1
Leishmania major beta tubulin 0.1695 0.4948 1
Brugia malayi hypothetical protein 0.0106 0.0259 0.0524
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0013 0.0013
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0048 0.0088
Entamoeba histolytica hypothetical protein 0.0044 0.0078 0.0158
Echinococcus multilocularis survival motor neuron protein 1 0.0246 0.0672 0.0672
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0044 0.0069
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0013 0.0025
Trichomonas vaginalis tubulin epsilon chain, putative 0.1292 0.376 0.7599
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0423 0.1194 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0034 0.0034
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0227 0.0616 0.5134
Onchocerca volvulus 0.003 0.0034 0.0149
Loa Loa (eye worm) doublecortin family protein 0.0163 0.0427 0.0864
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0288 0.2376
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0134 0.1087
Schistosoma mansoni zinc finger protein 0.003 0.0034 0.0054
Echinococcus multilocularis ecdysone induced protein 78C 0.0068 0.0149 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0078 0.0158
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0259 0.0712 0.1123
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0288 0.2376
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0288 0.0454
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0068 0.0149 0.03
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.017 0.0344
Echinococcus granulosus single minded 2 0.0151 0.0393 0.062
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0011 0.0055
Schistosoma mansoni hypothetical protein 0.0047 0.0087 0.0137
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0039 0.0061 0.0061
Schistosoma mansoni lamin 0.0085 0.0197 0.0311
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.006 0.0125 0.0253
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0039 0.0061 0.0097
Loa Loa (eye worm) hypothetical protein 0.0869 0.2513 0.5078
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0288 0.0581
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0044 0.0078 0.0158
Trypanosoma brucei alpha tubulin 0.1292 0.376 0.7599
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Echinococcus granulosus alpha tubulin 0.1292 0.376 0.5931
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0095 0.0191
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0011 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0083
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0013 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0115 0.0232
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0048 0.0098
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0003 0.0005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0048 0.0366
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0039 0.0079
Brugia malayi Tubulin gamma chain 0.0967 0.2802 0.5663
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0048 0.0098
Brugia malayi nuclear hormone receptor 0.003 0.0034 0.0069
Onchocerca volvulus 0.0151 0.0393 0.1843
Echinococcus multilocularis tumor protein p63 0.1398 0.4073 0.4073
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0054 0.0106 0.0215
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Leishmania major beta tubulin 0.1695 0.4948 1
Schistosoma mansoni hypothetical protein 0.0211 0.0569 0.0897
Echinococcus granulosus Tubulin beta 2C chain 0.1695 0.4948 0.7805
Trichomonas vaginalis tubulin beta chain, putative 0.1292 0.376 0.7599
Schistosoma mansoni hypothetical protein 0.0879 0.2541 0.4008
Echinococcus multilocularis Tubulin beta 2C chain 0.1695 0.4948 0.4948
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0107 0.0262 0.0529
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0288 0.0581
Plasmodium vivax tubulin alpha chain, putative 0.1292 0.376 0.7596
Brugia malayi bHLH-PAS transcription factor 0.0151 0.0393 0.0795
Echinococcus multilocularis tubulin alpha 0.0939 0.2718 0.2718
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.006 0.0095
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0039 0.0079
Loa Loa (eye worm) hypothetical protein 0.0088 0.0208 0.042
Trichomonas vaginalis tubulin alpha chain, putative 0.0939 0.2718 0.5493
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0043 0.0086
Schistosoma mansoni z-protein (S1r protein) 0.0044 0.0078 0.0123
Echinococcus multilocularis cpg binding protein 0.0093 0.0222 0.0222
Giardia lamblia Epsilon tubulin 0.0451 0.1277 0.2574
Loa Loa (eye worm) hypothetical protein 0.0088 0.0208 0.042
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0048 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0207 0.0418
Onchocerca volvulus 0.0205 0.0551 0.2586
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0048 0.0088
Brugia malayi alpha-tubulin 0.1292 0.376 0.7599
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0288 0.0454
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0011 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0228 0.046
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0044 0.0089
Brugia malayi hypothetical protein 0.0204 0.0548 0.1107
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0098
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0034 0.0034
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0011 0.0055
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.004 0.0064 0.0128
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0088
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0039 0.0069
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0041 0.0065
Schistosoma mansoni tubulin subunit gamma 0.0967 0.2802 0.442
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.0803 0.1623
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0288 0.0581
Schistosoma mansoni hypothetical protein 0.0879 0.2541 0.4008
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0022 0.0043
Brugia malayi SPARC precursor 0.006 0.0125 0.0253
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0011 0.0055
Loa Loa (eye worm) hypothetical protein 0.0068 0.0149 0.03
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0048 0.0088
Echinococcus granulosus CREB binding protein 0.0033 0.0044 0.0069
Loa Loa (eye worm) hypothetical protein 0.0088 0.0208 0.042
Loa Loa (eye worm) histone methyltransferase 0.0031 0.0038 0.0076
Trypanosoma brucei alpha tubulin, putative 0.0516 0.1471 0.2972
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Brugia malayi nuclear receptor NHR-67 0.003 0.0034 0.0069
Echinococcus multilocularis CREB binding protein 0.0033 0.0044 0.0044
Plasmodium vivax thioredoxin reductase, putative 0.0099 0.024 0.0476
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0252 0.069 0.1394
Toxoplasma gondii beta-1 tubulin, putative 0.1695 0.4948 1
Schistosoma mansoni tubulin subunit epsilon 0.0967 0.2801 0.4418
Echinococcus multilocularis regulator of G protein signaling 3 0.0044 0.0078 0.0078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0098
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0078 0.0123
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.001 0.0015
Leishmania major zeta tubulin, putative 0.0717 0.2063 0.4163
Plasmodium vivax multidomain scavenger receptor, putative 0.0163 0.0427 0.0855
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0053 0.0104 0.0209
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.003 0.0035 0.0035
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0048 0.0088
Brugia malayi tubulin alpha chain - mouse 0.1292 0.376 0.7599
Loa Loa (eye worm) MH2 domain-containing protein 0.062 0.1777 0.3591
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0044 0.0079
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0041 0.0041
Brugia malayi secreted modular calcium-binding protein 1 0.006 0.0125 0.0253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0048 0.0098
Brugia malayi hypothetical protein 0.0378 0.1063 0.2148
Echinococcus multilocularis dnaJ subfamily B 0.0852 0.2462 0.2462
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0069
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0039 0.1544
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Treponema pallidum NADH oxidase 0.0034 0.0048 0.0366
Brugia malayi nuclear receptor NHR-88 0.003 0.0034 0.0069
Echinococcus granulosus geminin 0.0879 0.2541 0.4008
Giardia lamblia Beta tubulin 0.1695 0.4948 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.0156 0.0315
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0072 0.0145
Loa Loa (eye worm) hypothetical protein 0.0108 0.0265 0.0536
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0041 0.0065
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0149 0.0235
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.006 0.0112
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0013 0.0025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0005 0.001
Plasmodium falciparum alpha tubulin 1 0.1292 0.376 0.7596
Trichomonas vaginalis tubulin gamma chain, putative 0.1695 0.4948 1
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0869 0.2513 0.5078
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0015 0.0088
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0009 0.0035
Onchocerca volvulus 0.025 0.0684 0.3216
Loa Loa (eye worm) RecQ helicase 0.0043 0.0073 0.0148
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0045 0.008 0.0161
Schistosoma mansoni axis inhibition protein axin 0.0044 0.0078 0.0123
Plasmodium vivax tubulin epsilon chain, putative 0.0967 0.2801 0.5656
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0039 0.0079
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0068 0.0149 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0078 0.0158
Loa Loa (eye worm) hypothetical protein 0.0044 0.0078 0.0158
Echinococcus multilocularis CREB binding protein 0.0137 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0023 0.0016 0.0032
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0073 0.0073
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0081 0.0128
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0173 0.0272
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1695 0.4948 0.4948
Trypanosoma brucei alpha tubulin 0.1292 0.376 0.7599
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0009 0.0035
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0011 0.0055
Trypanosoma cruzi MFS transporter, putative 0.0088 0.0208 0.042
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0039 0.1544
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0034 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0011 0.0055
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0003 0.0004
Echinococcus multilocularis transfer RNA-Lys 0.0151 0.0393 0.0393
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0095 0.0228 0.0359
Loa Loa (eye worm) tubulin alpha-2 chain 0.1292 0.376 0.7599
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0288 0.2376
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0003 0.0005
Echinococcus multilocularis tubulin alpha chain 0.1292 0.376 0.376
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0013 0.0025
Echinococcus multilocularis Regulator of G protein signaling 20 0.0044 0.0078 0.0078
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0039 0.0061 0.0124
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0013 0.0025
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0013 0.0013
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0005 0.001
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0776 0.2236 0.4519
Echinococcus granulosus smad 0.0042 0.0072 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0012
Toxoplasma gondii transporter, major facilitator family protein 0.0088 0.0208 0.042
Loa Loa (eye worm) tubulin beta chain 0.1695 0.4948 1
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0207 0.0326
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0262 0.0529
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0013 0.002
Leishmania major beta tubulin 0.1695 0.4948 1
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0288 0.0581
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0006 0.0012
Schistosoma mansoni tubulin subunit beta 0.1695 0.4948 0.7805
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0048 0.2102
Giardia lamblia Fructose-bisphosphate aldolase 0.029 0.0803 0.1614
Echinococcus granulosus dnaJ subfamily B 0.0852 0.2462 0.3884
Mycobacterium ulcerans hypothetical protein 0.0021 0.0009 0.0035
Trypanosoma brucei alpha tubulin 0.1292 0.376 0.7599
Brugia malayi Nuclear hormone receptor E75 0.003 0.0034 0.0069
Brugia malayi ABC transporter family protein 0.0022 0.0013 0.0025
Echinococcus granulosus Tubulin beta 2C chain 0.1695 0.4948 0.7805
Trypanosoma brucei epsilon tubulin 0.0967 0.2801 0.5661
Trichomonas vaginalis tubulin epsilon chain, putative 0.1695 0.4948 1
Leishmania major alpha tubulin 0.1292 0.376 0.7596
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0013 0.0025
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0034 0.0069
Loa Loa (eye worm) hypothetical protein 0.0088 0.0208 0.042
Leishmania major protein kinase, putative 0.0054 0.0106 0.0205
Trypanosoma brucei alpha tubulin 0.1292 0.376 0.7599
Schistosoma mansoni retinoic acid receptor RXR 0.0068 0.0149 0.0234
Brugia malayi ecdysone receptor 0.003 0.0034 0.0069
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0013 0.0025
Echinococcus granulosus jun protein 0.0259 0.0712 0.1123
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0599 0.1714 0.3464
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.0029 0.0045
Echinococcus multilocularis beta tubulin 0.1695 0.4948 0.4948
Mycobacterium tuberculosis Probable dehydrogenase 0.0227 0.0616 0.5134
Schistosoma mansoni steroid hormone receptor ad4bp 0.0068 0.0149 0.0234
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0054 0.0106 0.0215
Brugia malayi Cytochrome P450 family protein 0.0022 0.0011 0.0023
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0149 0.0302
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0011 0.0055
Onchocerca volvulus 0.0068 0.0149 0.0689
Brugia malayi hypothetical protein 0.0088 0.0208 0.042
Trichomonas vaginalis tubulin beta chain, putative 0.1292 0.376 0.7599
Schistosoma mansoni hypothetical protein 0.0852 0.2462 0.3884
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.006 0.006
Giardia lamblia Gamma tubulin 0.0967 0.2802 0.5659
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0107 0.0262 0.0529
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0003 0.0005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0068 0.0149 0.0234
Brugia malayi follicle stimulating hormone receptor 0.0252 0.069 0.1394
Schistosoma mansoni smdr2 0.0022 0.0013 0.002
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0085 0.0197 0.0399
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0068 0.0149 0.0234
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0044 0.0069
Echinococcus granulosus neuropeptide receptor A26 0.0968 0.2802 0.4421
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0005
Plasmodium falciparum alpha tubulin 2 0.1292 0.376 0.7596
Echinococcus multilocularis aryl hydrocarbon receptor 0.0053 0.0104 0.0104
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0083 0.0193 0.0389
Echinococcus multilocularis lamin 0.0085 0.0197 0.0197
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.02 0.0538 0.0849
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.006 0.0122
Toxoplasma gondii LsmAD domain-containing protein 0.0106 0.0259 0.0524
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.0259 0.0515
Entamoeba histolytica recQ family helicase, putative 0.0032 0.0043 0.0086
Brugia malayi Tubulin alpha chain 0.1292 0.376 0.7599
Echinococcus multilocularis CREB binding protein 0.0033 0.0044 0.0044
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0044 0.0089
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0516 0.1471 0.2972
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0005 0.0008
Leishmania major beta tubulin 0.1695 0.4948 1
Echinococcus granulosus Solute carrier organic anion transporter family 0.0088 0.0208 0.0328
Loa Loa (eye worm) hypoxia-induced factor 1 0.0632 0.1813 0.3665
Trypanosoma cruzi epsilon tubulin, putative 0.0967 0.2801 0.5661
Brugia malayi steroid hormone receptor 0.0068 0.0149 0.03
Echinococcus granulosus ATP dependent DNA helicase Q1 0.003 0.0035 0.0055
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0048 0.0088
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0149 0.0302
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0053 0.0104 0.0209
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0048 0.0098
Trichomonas vaginalis taga, putative 0.0022 0.0013 0.0025
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0083
Loa Loa (eye worm) tubulin alpha 2 0.0353 0.0989 0.1998
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0037 0.0074
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1292 0.376 0.7599
Onchocerca volvulus 0.0088 0.0208 0.0969
Loa Loa (eye worm) intermediate filament protein 0.0085 0.0197 0.0399
Trichomonas vaginalis tubulin epsilon chain, putative 0.1695 0.4948 1
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0013 0.0013

Activities

Activity type Activity value Assay description Source Reference
ID50 (functional) = 0.38 mg/day Inhibition of testoterone-induced prostate weight in castrated immature Sprague-Dawley rat ChEMBL. 17134895
Inhibition (functional) = 84 % Inhibition of testoterone-induced prostate weight in castrated immature Sprague-Dawley rat at 2 mg/day relative to control ChEMBL. 17134895

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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