Detailed information for compound 441626

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 326.78 | Formula: C17H15ClN4O
  • H donors: 1 H acceptors: 3 LogP: 2.88 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)NC(=O)c1ccnn1CCc1ccccn1
  • InChi: 1S/C17H15ClN4O/c18-13-4-6-15(7-5-13)21-17(23)16-8-11-20-22(16)12-9-14-3-1-2-10-19-14/h1-8,10-11H,9,12H2,(H,21,23)
  • InChiKey: JGXHIVBAKQWZHX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens kinase insert domain receptor Starlite/ChEMBL References
Homo sapiens fms-related tyrosine kinase 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Get druggable targets OG5_130320 All targets in OG5_130320
Onchocerca volvulus Tyrosine kinase homolog Get druggable targets OG5_130320 All targets in OG5_130320
Loa Loa (eye worm) TK/KIN16 protein kinase Get druggable targets OG5_130320 All targets in OG5_130320
Brugia malayi Immunoglobulin I-set domain containing protein Get druggable targets OG5_130320 All targets in OG5_130320
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis neurogenic locus protein delta 0.0339 0.1332 0.1858
Echinococcus granulosus neuropeptide receptor A26 0.1619 0.6632 0.7471
Trypanosoma brucei unspecified product 0.0036 0.0077 0.0412
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0029 0.0049 0.0065
Mycobacterium tuberculosis Conserved protein 0.0256 0.0987 0.5251
Trichomonas vaginalis guanylate cyclase, putative 0.0053 0.0147 0.034
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Schistosoma mansoni hypothetical protein 0.0339 0.1332 0.1331
Onchocerca volvulus 0.0033 0.0066 0.006
Brugia malayi Calcium binding EGF domain containing protein 0.0339 0.1332 0.1331
Loa Loa (eye worm) hypothetical protein 0.2433 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.0683 0.2755 0.2751
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0056 0.016 0.022
Echinococcus granulosus laminin 0.0112 0.039 0.0438
Echinococcus granulosus chromobox protein 2 0.0024 0.0029 0.003
Echinococcus multilocularis epidermal growth factor receptor 0.0157 0.0577 0.0803
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0058 0.0167 0.0186
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0047 0.0121 0.0647
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.012 0.063
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0082 0.027 0.0301
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0131 0.0472 0.0657
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.008 0.0341
Echinococcus granulosus voltage gated potassium channel subunit 0.0256 0.0987 0.111
Echinococcus granulosus neuropeptide receptor 0.0082 0.027 0.0301
Schistosoma mansoni hypothetical protein 0.0339 0.1332 0.1331
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Echinococcus multilocularis ecdysone induced protein 78C 0.0106 0.0366 0.0509
Loa Loa (eye worm) hypothetical protein 0.0197 0.0744 0.0738
Onchocerca volvulus 0.0224 0.0855 0.0849
Mycobacterium tuberculosis Probable oxidoreductase 0.013 0.0468 0.2481
Echinococcus multilocularis insulin receptor 0.0051 0.0139 0.0191
Trypanosoma brucei THT1 - hexose transporter, putative 0.0019 0.0006 0.0034
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0053 0.0147 0.0774
Echinococcus multilocularis acetylcholinesterase 0.0197 0.0744 0.1036
Schistosoma mansoni hypothetical protein 0.0131 0.0472 0.0471
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0092
Loa Loa (eye worm) glutathione reductase 0.0051 0.0141 0.0135
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0082 0.027 0.0301
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0131 0.0472 0.053
Schistosoma mansoni biogenic amine receptor 0.0082 0.027 0.0268
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0034
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Schistosoma mansoni cell adhesion molecule 0.0034 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0106 0.0366 0.036
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0047 0.0121 0.0637
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0595 0.2391 0.2386
Schistosoma mansoni tyrosine kinase 0.0157 0.0577 0.0575
Echinococcus multilocularis peroxidasin 0.1747 0.7161 1
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0029 0.0063
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0047 0.0121 0.0637
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0047 0.0121 0.0637
Trichomonas vaginalis aldo-keto reductase, putative 0.0256 0.0987 0.2309
Onchocerca volvulus Arrow homolog 0.0112 0.039 0.0384
Echinococcus granulosus Solute carrier family 22 5 0.2162 0.8876 1
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0161 0.0847
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0029 0.0063
Echinococcus granulosus neuropeptides capa receptor 0.0082 0.027 0.0301
Schistosoma mansoni sugar transporter 0.0019 0.0006 0.0004
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0029 0.0063
Loa Loa (eye worm) MH2 domain-containing protein 0.0108 0.0373 0.0367
Schistosoma mansoni hypothetical protein 0.0339 0.1332 0.1331
Loa Loa (eye worm) hypothetical protein 0.0112 0.039 0.0384
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.008 0.0341
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0019 0.0006 0.0034
Leishmania major protein kinase, putative 0.0053 0.0147 0.0774
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Onchocerca volvulus 0.0106 0.0366 0.036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0029 0.0063
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Onchocerca volvulus Putative cubilin 0.0339 0.1332 0.1327
Schistosoma mansoni lamin 0.0119 0.0423 0.0421
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0106 0.0563
Schistosoma mansoni netrin receptor unc5 0.005 0.0135 0.0133
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Mycobacterium leprae putative cytochrome p450 0.0047 0.0121 0.0564
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.0189
Brugia malayi latrophilin 2 splice variant baaae 0.0057 0.0163 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Schistosoma mansoni chromobox protein 0.0024 0.0029 0.0027
Brugia malayi nuclear receptor NHR-88 0.005 0.0135 0.0133
Brugia malayi Sugar transporter family protein 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0663 0.2673 0.373
Schistosoma mansoni ap endonuclease 0.0037 0.008 0.0078
Brugia malayi Dopamine receptor 0.0082 0.027 0.0268
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0029 0.0063
Brugia malayi Immunoglobulin I-set domain containing protein 0.041 0.1627 0.1626
Loa Loa (eye worm) hypothetical protein 0.0056 0.016 0.0153
Plasmodium vivax sugar transporter, putative 0.0019 0.0006 0.003
Trypanosoma cruzi hexose transporter 0.0019 0.0006 0.0023
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.0448 0.0442
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0106 0.0366 0.0364
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0106 0.0366 0.0509
Brugia malayi neuropeptide F receptor 0.0082 0.027 0.0268
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0082 0.027 0.0374
Brugia malayi Pre-SET motif family protein 0.0921 0.3743 0.3741
Echinococcus multilocularis tissue type plasminogen activator 0.0354 0.1393 0.1943
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0029 0.0063
Loa Loa (eye worm) hypothetical protein 0.0224 0.0855 0.0849
Schistosoma mansoni amine GPCR 0.0082 0.027 0.0268
Brugia malayi nuclear hormone receptor 0.005 0.0135 0.0133
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0034 0.0067 0.0073
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0002 0.0011
Brugia malayi NADH-dependent xylose reductase 0.0256 0.0987 0.0985
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.027 0.0301
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0448 0.1045
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0471 0.1878 0.2114
Brugia malayi flavodoxin family protein 0.0028 0.0044 0.0042
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.013 0.0468 0.2481
Giardia lamblia Fructose-bisphosphate aldolase 0.0568 0.2279 1
Echinococcus multilocularis aldo keto reductase 0.0471 0.1878 0.2621
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0053 0.0147 0.034
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0043 0.0107 0.0709
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0374 0.1475 0.7852
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.001
Echinococcus granulosus transmembrane protease serine 3 0.0224 0.0855 0.0962
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0053 0.0147 0.034
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.0448 0.2386
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0082 0.027 0.0268
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0471 0.1878 1
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0339 0.1332 0.1331
Echinococcus granulosus delta-like protein 1 0.0339 0.1332 0.1499
Schistosoma mansoni thyroid hormone receptor 0.0237 0.0911 0.0909
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Toxoplasma gondii glyoxalase I, putative 0.0374 0.1475 0.7852
Echinococcus multilocularis dro:myosuppressin receptor 0.0082 0.027 0.0374
Onchocerca volvulus 0.0029 0.0049 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.001
Echinococcus multilocularis Immunoglobulin 0.0025 0.0033 0.0043
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0117 0.0413 0.2193
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0097
Echinococcus granulosus nuclear receptor nhr 48 0.005 0.0135 0.015
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0082 0.027 0.0374
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.013 0.0468 0.2423
Echinococcus granulosus neurogenic locus notch protein 0.0339 0.1332 0.1499
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0044 0.0099
Loa Loa (eye worm) steroid hormone receptor 0.0106 0.0366 0.036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.027 0.0268
Plasmodium falciparum nitric oxide synthase, putative 0.0028 0.0044 0.0284
Schistosoma mansoni glucose transport protein 0.0051 0.014 0.0138
Mycobacterium ulcerans hypothetical protein 0.0086 0.0286 0.1515
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0256 0.0987 0.2309
Brugia malayi Major Facilitator Superfamily protein 0.0019 0.0006 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0011 0.0046
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0123 0.0469
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.008 0.0087
Giardia lamblia Nitric oxide synthase, inducible 0.0025 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0224 0.0855 0.0849
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0132 0.0475 0.0473
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0029 0.0143
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0119 0.0423 0.0416
Echinococcus granulosus serotonin receptor 0.0082 0.027 0.0301
Schistosoma mansoni hypothetical protein 0.0026 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0112 0.039 0.0384
Schistosoma mansoni aldo-keto reductase 0.0471 0.1878 0.1877
Plasmodium vivax glyoxalase I, putative 0.0374 0.1475 1
Brugia malayi Delta serrate ligand family protein 0.0339 0.1332 0.1331
Schistosoma mansoni lamin 0.0119 0.0423 0.0421
Brugia malayi hypothetical protein 0.0133 0.0479 0.0477
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0053 0.0147 0.0203
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0103 0.0537
Echinococcus granulosus BC026374 protein S09 family 0.0033 0.0066 0.0072
Echinococcus granulosus neuroligin 0.0033 0.0066 0.0072
Brugia malayi PAS domain containing protein 0.0204 0.0771 0.0769
Loa Loa (eye worm) nuclear receptor NHR-67 0.005 0.0135 0.0129
Echinococcus multilocularis RUN 0.0041 0.0099 0.0135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.0029 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0029 0.0063
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Onchocerca volvulus Putative organic anion transporter 0.0029 0.0049 0.0042
Schistosoma mansoni opsin-like receptor 0.0082 0.027 0.0268
Toxoplasma gondii sugar transporter ST3 0.0019 0.0006 0.0023
Trichomonas vaginalis sugar transport protein, putative 0.0019 0.0006 0.001
Echinococcus multilocularis solute carrier family 22 0.0019 0.0006 0.0006
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0011 0.0009
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0028 0.0044 0.0233
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0448 0.1045
Loa Loa (eye worm) oxidoreductase 0.0471 0.1878 0.1873
Toxoplasma gondii transporter, major facilitator family protein 0.0019 0.0006 0.0023
Echinococcus granulosus neurogenic locus protein delta 0.0339 0.1332 0.1499
Loa Loa (eye worm) hypothetical protein 0.0039 0.009 0.0084
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Echinococcus multilocularis neuropeptide Y receptor 0.0082 0.027 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0123 0.0282
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.0103 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0106 0.0366 0.0411
Onchocerca volvulus 0.0471 0.1878 0.1873
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0339 0.1332 0.1331
Echinococcus granulosus neuropeptide s receptor 0.1619 0.6632 0.7471
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0123 0.0116
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Loa Loa (eye worm) hypothetical protein 0.0197 0.0744 0.0738
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.027 0.0268
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0135 0.015
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Mycobacterium ulcerans hypothetical protein 0.0086 0.0286 0.1515
Giardia lamblia Sugar-proton symporter 0.0019 0.0006 0.0019
Schistosoma mansoni hypothetical protein 0.0133 0.0479 0.0477
Trypanosoma cruzi aldo-keto reductase 0.0471 0.1878 1
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0224 0.0855 0.0853
Schistosoma mansoni polycystin 1-related 0.0041 0.0099 0.0097
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0082 0.027 0.0268
Onchocerca volvulus 0.1733 0.71 0.7099
Echinococcus granulosus lamin 0.0119 0.0423 0.0474
Toxoplasma gondii sugar transporter ST2 0.0019 0.0006 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.027 0.0374
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.008 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0029 0.0063
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0056 0.016 0.0158
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0047 0.0121 0.0637
Loa Loa (eye worm) oxidoreductase 0.0471 0.1878 0.1873
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0126 0.0448 0.196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0033 0.0073
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Echinococcus multilocularis roundabout 2 0.004 0.0094 0.0128
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0471 0.1878 0.2114
Brugia malayi Thioredoxin reductase 0.0051 0.0141 0.0139
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0047 0.0121 0.0637
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0256 0.0987 0.111
Echinococcus granulosus chromobox protein 1 0.0088 0.0291 0.0326
Schistosoma mansoni lipoxygenase 0.0172 0.0641 0.0639
Mycobacterium ulcerans hypothetical protein 0.0256 0.0987 0.5251
Brugia malayi orphan nuclear receptor NR2E1 0.005 0.0135 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0029 0.0063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0156
Mycobacterium tuberculosis Conserved protein 0.0086 0.0286 0.1515
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0012 0.0006
Schistosoma mansoni inositol monophosphatase 0.0042 0.0103 0.0101
Trypanosoma brucei aldo/keto reductase, putative 0.0256 0.0987 0.5256
Echinococcus granulosus FTZ F1 alpha 0.0106 0.0366 0.0411
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0029 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Brugia malayi larval opioid receptor 0.0082 0.027 0.0268
Mycobacterium ulcerans epoxide hydrolase EphA 0.0171 0.0635 0.3372
Brugia malayi Trypsin family protein 0.0224 0.0855 0.0853
Schistosoma mansoni chromobox protein 0.0024 0.0029 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0106 0.0366 0.0364
Loa Loa (eye worm) hypothetical protein 0.0374 0.1475 0.147
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0053 0.0147 0.0774
Brugia malayi Carboxylesterase family protein 0.0033 0.0066 0.0064
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.0103 0.0537
Echinococcus granulosus epidermal growth factor receptor 0.0157 0.0577 0.0648
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0056 0.016 0.0158
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0097
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.07 0.1636
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Echinococcus granulosus alpha 1A adrenergic receptor 0.0082 0.027 0.0301
Mycobacterium ulcerans glyoxalase GloA 0.0086 0.0286 0.1515
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0069 0.0453
Brugia malayi EGF-like domain containing protein 0.0339 0.1332 0.1331
Schistosoma mansoni pol-related 0.0471 0.1878 0.1877
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0047 0.0121 0.0637
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.027 0.0301
Onchocerca volvulus 0.005 0.0135 0.0129
Loa Loa (eye worm) hypothetical protein 0.0384 0.1517 0.1512
Loa Loa (eye worm) hypothetical protein 0.0106 0.0366 0.036
Onchocerca volvulus 0.0339 0.1332 0.1327
Brugia malayi ecdysteroid receptor 0.0106 0.0366 0.0364
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.012 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0153 0.0354
Echinococcus granulosus epidermal growth factor receptor 0.0085 0.0279 0.0312
Brugia malayi Carboxylesterase family protein 0.0033 0.0066 0.0064
Trichomonas vaginalis chromobox protein, putative 0.0088 0.0291 0.0677
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0256 0.0987 0.5251
Schistosoma mansoni neuropeptide f receptor 76f 0.0082 0.027 0.0268
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0135 0.015
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Echinococcus granulosus tachykinin peptides receptor 99D 0.0082 0.027 0.0301
Echinococcus granulosus defective proboscis extension response 0.0025 0.0033 0.0035
Brugia malayi ecdysone receptor 0.005 0.0135 0.0133
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0027
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0297 0.029
Brugia malayi Furin-like cysteine rich region family protein 0.0157 0.0577 0.0575
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0028 0.0044 0.0058
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0082 0.027 0.0374
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0047 0.0121 0.0637
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.027 0.1045 0.1043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Leishmania major aldo-keto reductase-like protein 0.0471 0.1878 1
Echinococcus granulosus nuclear factor of activated T cells 5 0.0214 0.0814 0.0915
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0073 0.0166
Trichomonas vaginalis aldo-keto reductase, putative 0.0256 0.0987 0.2309
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0132 0.0475 0.0661
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0123 0.0469
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0011 0.0009
Plasmodium falciparum heterochromatin protein 1 0.0024 0.0029 0.0182
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Schistosoma mansoni nuclear receptor 0.005 0.0135 0.0133
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.0029 0.0038
Loa Loa (eye worm) animal heme peroxidase 0.1733 0.71 0.7099
Brugia malayi Cytochrome P450 family protein 0.0056 0.0161 0.0159
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.0448 0.2378
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0082 0.027 0.0268
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0047 0.0121 0.0637
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.2279 0.5335
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Schistosoma mansoni notch 0.0339 0.1332 0.1331
Brugia malayi Cytochrome P450 family protein 0.0056 0.0161 0.0159
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0471 0.1878 0.2114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0073 0.0166
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0106 0.0366 0.0364
Echinococcus granulosus tm gpcr rhodopsin 0.0082 0.027 0.0301
Schistosoma mansoni zinc finger protein 0.005 0.0135 0.0133
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0019 0.0006 0.0023
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0047 0.0121 0.0637
Echinococcus multilocularis netrin receptor unc 5 0.005 0.0135 0.0186
Echinococcus multilocularis 0.0047 0.0121 0.0167
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Leishmania major ATP-dependent phosphofructokinase 0.0126 0.0448 0.2378
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0106 0.0366 0.036
Onchocerca volvulus Putative organic anion transporter 0.0029 0.0049 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0156 0.0576 0.0574
Schistosoma mansoni DNA helicase recq5 0.002 0.0012 0.001
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0017 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0256 0.0987 0.2309
Echinococcus granulosus protein jagged 2 0.0339 0.1332 0.1499
Onchocerca volvulus 0.0156 0.0576 0.057
Brugia malayi Calcium binding EGF domain containing protein 0.0339 0.1332 0.1331
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0092
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Brugia malayi hypothetical protein 0.0041 0.0099 0.0097
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.0106 0.0243
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0034
Schistosoma mansoni DNA helicase recq1 0.002 0.0012 0.001
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0082 0.027 0.0268
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0167 0.0386
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0029 0.0063
Brugia malayi cytoplasmic intermediate filament protein 0.0064 0.0193 0.0191
Schistosoma mansoni lozenge 0.0064 0.0194 0.0192
Echinococcus granulosus enteropeptidase 0.0224 0.0855 0.0962
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.027 0.0268
Loa Loa (eye worm) animal heme peroxidase 0.1733 0.71 0.7099
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Giardia lamblia High cysteine protein 0.0339 0.1332 0.5844
Schistosoma mansoni nuclear receptor nhr-48 0.005 0.0135 0.0133
Brugia malayi secreted modular calcium-binding protein 1 0.002 0.0011 0.0009
Brugia malayi Dopamine receptor protein 1 0.0082 0.027 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0047 0.0121 0.0637
Leishmania major glucose transporter/membrane transporter D2, putative 0.0019 0.0006 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0106 0.0366 0.0364
Schistosoma mansoni transcription factor LCR-F1 0.0133 0.0479 0.0477
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0061
Loa Loa (eye worm) oxidoreductase 0.0471 0.1878 0.1873
Schistosoma mansoni glucose transport protein 0.0051 0.014 0.0138
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0028 0.0044 0.0223
Echinococcus multilocularis g protein coupled receptor 0.0082 0.027 0.0374
Treponema pallidum fructose-bisphosphate aldolase 0.0568 0.2279 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0073 0.0166
Entamoeba histolytica hypothetical protein 0.0133 0.0479 0.2043
Trichomonas vaginalis guanylate cyclase, putative 0.0053 0.0147 0.034
Giardia lamblia Hypothetical protein 0.0025 0.0031 0.0126
Brugia malayi Tachykinin-like peptides receptor 99D 0.0082 0.027 0.0268
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0183 0.0203
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0042
Echinococcus granulosus Chromobox protein 3 0.0024 0.0029 0.003
Brugia malayi intermediate filament protein 0.0119 0.0423 0.0421
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0082 0.027 0.0268
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0019 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Leishmania major cathepsin L-like protease 0.0057 0.0166 0.0872
Echinococcus multilocularis sex peptide receptor 0.0082 0.027 0.0374
Echinococcus multilocularis neuropeptide FF receptor 2 0.0082 0.027 0.0374
Schistosoma mansoni chromobox protein 0.0088 0.0291 0.0289
Brugia malayi Inositol-1 0.0042 0.0103 0.0101
Brugia malayi hypothetical protein 0.0041 0.0099 0.0097
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0568 0.2279 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0073 0.0166
Echinococcus multilocularis geminin 0.0143 0.052 0.0723
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0029 0.0055
Giardia lamblia GTOR 0.0047 0.0123 0.0529
Schistosoma mansoni vesicular amine transporter 0.0025 0.0033 0.0031
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0921 0.3743 0.3738
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Echinococcus granulosus fmrfamide receptor 0.0082 0.027 0.0301
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0029 0.0182
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0112 0.039 0.0389
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0082 0.027 0.0263
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0256 0.0987 0.6687
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Echinococcus granulosus roundabout 2 0.004 0.0094 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0106 0.0563
Brugia malayi Carboxylesterase family protein 0.0197 0.0744 0.0742
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0086 0.0286 0.028
Plasmodium vivax SET domain protein, putative 0.0132 0.0475 0.3213
Onchocerca volvulus 0.0033 0.0066 0.006
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0019 0.0006 0.0023
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0183 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0011 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0106 0.0366 0.0364
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Loa Loa (eye worm) heterochromatin protein 1 0.0088 0.0291 0.0285
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0069 0.0453
Brugia malayi nuclear hormone receptor family member odr-7 0.005 0.0135 0.0133
Leishmania major p450 reductase, putative 0.0028 0.0044 0.0223
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0042
Trypanosoma brucei glucose transporter 1E 0.0019 0.0006 0.0034
Echinococcus granulosus bloom syndrome protein 0.0049 0.0131 0.0146
Brugia malayi major facilitator superfamily protein 0.0019 0.0006 0.0004
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Loa Loa (eye worm) hypothetical protein 0.1747 0.7161 0.7159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0106 0.0366 0.036
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0073 0.0166
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0099 0.0109
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0033 0.0066 0.0342
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0103 0.0547
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0112 0.039 0.0384
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0106 0.0553
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.008 0.0279
Mycobacterium ulcerans carboxylesterase, LipT 0.0033 0.0066 0.0342
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0183 0.0203
Brugia malayi hypothetical protein 0.0046 0.012 0.0118
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0029 0.0063
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0224 0.0855 0.0853
Schistosoma mansoni slit 0.0339 0.1332 0.1331
Echinococcus multilocularis transmembrane protease serine 3 0.0224 0.0855 0.1192
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0106 0.0366 0.0364
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0047 0.0121 0.0637
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0029 0.0049 0.0042
Onchocerca volvulus 0.0224 0.0855 0.0849
Brugia malayi hypothetical protein 0.0029 0.0049 0.0047
Echinococcus multilocularis para nitrobenzyl esterase 0.0033 0.0066 0.009
Plasmodium falciparum glyoxalase I 0.0086 0.0286 0.193
Brugia malayi Protein kinase domain containing protein 0.0356 0.1401 0.1399
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0082 0.027 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0029 0.0063
Schistosoma mansoni hypothetical protein 0.0041 0.0099 0.0097
Echinococcus granulosus cytochrome P450 2K1 0.0047 0.0121 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0033 0.0073
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0166 0.0872
Loa Loa (eye worm) cytochrome P450 0.0047 0.0121 0.0115
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0123 0.0642
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0042 0.0101 0.0139
Schistosoma mansoni tyrosine kinase 0.0085 0.0279 0.0277
Loa Loa (eye worm) oxidoreductase 0.0471 0.1878 0.1873
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Echinococcus granulosus histone lysine methyltransferase setb 0.0132 0.0475 0.0533
Schistosoma mansoni nuclear hormone receptor 0.0106 0.0366 0.0364
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0117 0.0413 0.2193
Echinococcus multilocularis solute carrier family 22 0.0019 0.0006 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0017 0.0077
Brugia malayi hypothetical protein 0.0019 0.0006 0.0004
Onchocerca volvulus 0.0033 0.0066 0.006
Echinococcus granulosus aldehyde reductase 0.0215 0.082 0.0921
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0029 0.0063
Mycobacterium ulcerans glyoxalase GloA 0.0086 0.0286 0.1515
Schistosoma mansoni adenoreceptor 0.0082 0.027 0.0268
Onchocerca volvulus 0.0224 0.0855 0.0849
Echinococcus multilocularis protein jagged 1 0.0339 0.1332 0.1858
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0051 0.014 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0147 0.034
Brugia malayi photoreceptor-specific nuclear receptor 0.0106 0.0366 0.0364
Schistosoma mansoni hypothetical protein 0.0082 0.027 0.0268
Schistosoma mansoni amine GPCR 0.0082 0.027 0.0268
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0028 0.0044 0.0047
Brugia malayi MH2 domain containing protein 0.0108 0.0373 0.0371
Onchocerca volvulus 0.0082 0.027 0.0263
Onchocerca volvulus 0.0041 0.0099 0.0092
Toxoplasma gondii calcium binding egf domain-containing protein 0.0112 0.039 0.207
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0106 0.0563
Schistosoma mansoni nephrin 0.0032 0.006 0.0058
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0064 0.033
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0123 0.0136
Loa Loa (eye worm) G-protein coupled receptor 0.0082 0.027 0.0263
Onchocerca volvulus 0.0339 0.1332 0.1327
Loa Loa (eye worm) hypothetical protein 0.0056 0.016 0.0153
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0106 0.0553
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0117 0.0413 0.2193
Toxoplasma gondii calcium binding egf domain-containing protein 0.0112 0.039 0.207
Schistosoma mansoni nuclear receptor 0.005 0.0135 0.0133
Schistosoma mansoni agrin 0.002 0.0011 0.0009
Echinococcus multilocularis g protein coupled receptor 0.0082 0.027 0.0374
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0297 0.0332
Brugia malayi Cytochrome P450 family protein 0.0047 0.0121 0.0119
Onchocerca volvulus 0.0082 0.027 0.0263
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0106 0.0366 0.036
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0106 0.0366 0.036
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0135 0.0186
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0209 0.0792 0.0891
Brugia malayi Sugar transporter family protein 0.0019 0.0006 0.0004
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Brugia malayi follicle stimulating hormone receptor 0.0595 0.2391 0.2389
Echinococcus multilocularis solute carrier family 22 0.0019 0.0006 0.0006
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0471 0.1878 0.1877
Trypanosoma brucei aldo-keto reductase, putative 0.0471 0.1878 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0033 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.027 0.0374
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.008 0.0413
Brugia malayi Carboxylesterase family protein 0.0033 0.0066 0.0064
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0047 0.0121 0.0637
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0297 0.0295
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0082 0.027 0.0374
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0106 0.0366 0.0364
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0029 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.001
Onchocerca volvulus Glucosylceramidase homolog 0.0177 0.0661 0.0655
Echinococcus granulosus g protein coupled receptor 0.0082 0.027 0.0301
Schistosoma mansoni acetylcholinesterase 0.0033 0.0066 0.0064
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0053 0.0147 0.0774
Brugia malayi Sugar transporter family protein 0.0051 0.014 0.0138
Leishmania major cytochrome p450-like protein 0.0056 0.0161 0.0847
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0042 0.0101 0.0112
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.008 0.0526
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0161 0.0857
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0661 0.1544
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0017 0.0014
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0112 0.039 0.0389
Schistosoma mansoni hypothetical protein 0.0339 0.1332 0.1331
Loa Loa (eye worm) animal heme peroxidase 0.1739 0.7127 0.7125
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Loa Loa (eye worm) helicase 0.0024 0.0029 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0043 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.027 0.0374
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0029 0.0063
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0025 0.0033 0.0031
Schistosoma mansoni hypothetical protein 0.0024 0.0029 0.0027
Echinococcus granulosus netrin receptor unc 5 0.005 0.0135 0.015
Echinococcus multilocularis Ankyrin 0.0042 0.0103 0.0141
Echinococcus granulosus 6 phosphofructokinase 0.0126 0.0448 0.0503
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0094 0.0317 0.0355
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.2433 1 1
Brugia malayi dehydrogenases, short chain protein 2 0.0046 0.012 0.0118
Mycobacterium tuberculosis Conserved hypothetical protein 0.0086 0.0286 0.1515
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0028 0.0044 0.0223
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0082 0.027 0.0374
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0471 0.1878 0.4397
Loa Loa (eye worm) hypothetical protein 0.0057 0.0163 0.0156
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0028 0.0044 0.0284
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0135 0.0186
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0103 0.0236
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Brugia malayi nuclear receptor RXR 0.005 0.0135 0.0133
Brugia malayi hypothetical protein 0.0025 0.0033 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.027 0.0268
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0106 0.0366 0.0509
Trichomonas vaginalis aldo-keto reductase, putative 0.0256 0.0987 0.2309
Onchocerca volvulus 0.0082 0.027 0.0263
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0029 0.0063
Echinococcus granulosus hypothetical protein 0.0082 0.027 0.0301
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.0448 0.0446
Schistosoma mansoni amine GPCR 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.0118 0.0417 0.0411
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0133 0.0479 0.0666
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) Notch2 0.0339 0.1332 0.1327
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0099 0.0135
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.2279 0.5335
Loa Loa (eye worm) nuclear hormone receptor 0.005 0.0135 0.0129
Onchocerca volvulus Dual oxidase homolog 0.1733 0.71 0.7099
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0049 0.0249
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0069 0.0356
Brugia malayi Calcium binding EGF domain containing protein 0.0339 0.1332 0.1331
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.027 0.0301
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Echinococcus granulosus sex peptide receptor 0.0082 0.027 0.0301
Loa Loa (eye worm) hypoxia-induced factor 1 0.063 0.2536 0.2532
Brugia malayi major facilitator superfamily protein 0.0019 0.0006 0.0004
Onchocerca volvulus 0.0029 0.0049 0.0042
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0011 0.0046
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0019 0.0006 0.0435
Schistosoma mansoni hypothetical protein 0.0224 0.0855 0.0853
Echinococcus multilocularis neuropeptides capa receptor 0.0082 0.027 0.0374
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0082 0.027 0.0263
Echinococcus granulosus neurogenic locus notch protein 4 0.0339 0.1332 0.1499
Leishmania major glucose transporter, lmgt3 0.0019 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0042 0.0103 0.0096
Onchocerca volvulus 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.006
Schistosoma mansoni hypothetical protein 0.0026 0.0037 0.0035
Entamoeba histolytica aldose reductase, putative 0.0471 0.1878 0.8231
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0046 0.012 0.0118
Mycobacterium ulcerans 6-phosphofructokinase 0.0126 0.0448 0.2378
Brugia malayi Kringle domain containing protein 0.0354 0.1393 0.1391
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Toxoplasma gondii EGF family domain-containing protein 0.0339 0.1332 0.709
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0153 0.0354
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0246 0.0948 0.1321
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0033 0.0066 0.0072
Loa Loa (eye worm) hypothetical protein 0.0055 0.0158 0.0151
Loa Loa (eye worm) oxidoreductase 0.0471 0.1878 0.1873
Onchocerca volvulus 0.0021 0.0017 0.001
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Brugia malayi hypothetical protein 0.1733 0.71 0.71
Leishmania major cathepsin L-like protease 0.0057 0.0166 0.0872
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0086 0.0286 0.0284
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0023
Echinococcus multilocularis allatostatin A receptor 0.0082 0.027 0.0374
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0099 0.0657
Onchocerca volvulus 0.0375 0.1481 0.1475
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0029 0.0063
Brugia malayi hypothetical protein 0.0512 0.2047 0.2045
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0053 0.0147 1
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.0448 0.1908
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0106 0.0366 0.0411
Leishmania major myo-inositol/proton symporter (MIT) 0.0019 0.0006 0.0023
Entamoeba histolytica aldose reductase, putative 0.0471 0.1878 0.8231
Leishmania major glucose transporter, lmgt2 0.0019 0.0006 0.0023
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0012 0.0014
Toxoplasma gondii aldo-keto reductase 0.0256 0.0987 0.5251
Onchocerca volvulus 0.0082 0.027 0.0263
Schistosoma mansoni hypothetical protein 0.0339 0.1332 0.1331
Plasmodium falciparum glutathione reductase 0.0051 0.0141 0.0943
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0047 0.0121 0.0637
Mycobacterium tuberculosis Carboxylesterase LipT 0.0033 0.0066 0.0342
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0056 0.016 0.0178
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0033 0.0066 0.0431
Mycobacterium ulcerans hypothetical protein 0.0086 0.0286 0.1515
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.07 0.1636
Entamoeba histolytica hypothetical protein 0.0024 0.0029 0.0055
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0126 0.0448 0.2318
Onchocerca volvulus 0.005 0.0135 0.0129
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0082 0.027 0.0301
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.2433 1 1
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0099 0.0092
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0053 0.0147 0.034
Schistosoma mansoni single-minded 0.0204 0.0771 0.0769
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0106 0.0563
Schistosoma mansoni biogenic amine (5HT) receptor 0.0082 0.027 0.0268
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0094 0.0317 0.0315
Schistosoma mansoni cytochrome P450 reductase 0.0028 0.0044 0.0042
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0224 0.0855 0.0853
Echinococcus multilocularis Tolloid protein 1 0.0112 0.039 0.0543
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0029 0.0063
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.016 0.0158
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0082 0.027 0.0301
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0047 0.0121 0.0637
Echinococcus multilocularis lamin 0.0119 0.0423 0.0587
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.005 0.0135 0.0186
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0051 0.014 0.0155
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0047 0.0121 0.0637
Echinococcus granulosus neuropeptide Y receptor 0.0082 0.027 0.0301
Trypanosoma cruzi p450 reductase, putative 0.0028 0.0044 0.0223
Echinococcus granulosus neuroglian 0.0032 0.006 0.0065
Echinococcus granulosus chromobox protein 1 0.0088 0.0291 0.0326
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0025 0.0033 0.0031
Brugia malayi steroid hormone receptor 0.0106 0.0366 0.0364
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0083 0.0271 0.0265
Loa Loa (eye worm) hypothetical protein 0.0054 0.0153 0.0147
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0132 0.0475 0.2523
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Schistosoma mansoni notch 0.034 0.1334 0.1332
Loa Loa (eye worm) phosphofructokinase 0.0126 0.0448 0.0442
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0028 0.0044 0.0223
Brugia malayi Bloom's syndrome protein homolog 0.0049 0.0131 0.0129
Echinococcus granulosus protein jagged 1 0.0339 0.1332 0.1499
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0033 0.0066 0.0064
Echinococcus multilocularis notch 0.0339 0.1332 0.1858
Loa Loa (eye worm) hypothetical protein 0.0056 0.016 0.0153
Loa Loa (eye worm) carboxylesterase 0.0033 0.0066 0.006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.012 0.0118
Echinococcus multilocularis bloom syndrome protein 0.0049 0.0131 0.018
Echinococcus multilocularis chromobox protein 2 0.0024 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0042
Giardia lamblia DINP protein human, muc B family 0.0022 0.0019 0.0076
Echinococcus multilocularis laminin 0.0112 0.039 0.0543
Brugia malayi SPARC precursor 0.002 0.0011 0.0009
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0054 0.0153 0.0147
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0103 0.0537
Echinococcus granulosus neuropeptide FF receptor 2 0.0082 0.027 0.0301
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0103 0.0114
Brugia malayi Animal haem peroxidase family protein 0.1739 0.7127 0.7127
Mycobacterium tuberculosis Conserved protein TB27.3 0.0086 0.0286 0.1515
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.027 0.0374
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.005 0.0135 0.0133
Loa Loa (eye worm) G-protein coupled receptor 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0097
Echinococcus granulosus protein jagged 2 0.0339 0.1332 0.1499
Schistosoma mansoni gynecophoral canal protein 0.0086 0.0286 0.0284
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0197 0.0744 0.0742
Schistosoma mansoni biogenic amine receptor 0.0082 0.027 0.0268
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0106 0.0366 0.0411
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0047 0.0121 0.0637
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0054 0.0123
Echinococcus granulosus agrin 0.002 0.0011 0.001
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0029 0.003
Mycobacterium ulcerans putative regulatory protein 0.0151 0.0552 0.2931
Loa Loa (eye worm) hypothetical protein 0.0512 0.2047 0.2042
Brugia malayi hypothetical protein 0.0019 0.0006 0.0004
Brugia malayi G protein-coupled receptor F59B2.13 0.0082 0.027 0.0268
Schistosoma mansoni hypothetical protein 0.0057 0.0163 0.0161
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0099 0.0657
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0156
Schistosoma mansoni potassium channel beta 0.0256 0.0987 0.0985
Echinococcus multilocularis acetylcholinesterase 0.0197 0.0744 0.1036
Loa Loa (eye worm) melatonin receptor type 1A 0.0082 0.027 0.0263
Onchocerca volvulus 0.0224 0.0855 0.0849
Onchocerca volvulus 0.0082 0.027 0.0263
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0082 0.027 0.0374
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0141 0.0741
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0047 0.0121 0.0637
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0027
Brugia malayi small heat shock protein 0.0384 0.1517 0.1516
Schistosoma mansoni egf-like domain protein 0.0112 0.039 0.0389
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0029 0.0143
Trichomonas vaginalis sulfite reductase, putative 0.0028 0.0044 0.0098
Brugia malayi hypoxia-induced factor 1 0.063 0.2536 0.2535
Brugia malayi nuclear receptor NHR-67 0.005 0.0135 0.0133
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0029 0.0055
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Schistosoma mansoni microtubule-associated protein tau 0.0721 0.2911 0.291
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0026 0.0037 0.0049
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0471 0.1878 1
Onchocerca volvulus Chorion peroxidase homolog 0.1733 0.71 0.7099
Schistosoma mansoni neuropeptide F-like receptor 0.0082 0.027 0.0268
Brugia malayi hypothetical protein 0.005 0.0135 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0033 0.0073
Entamoeba histolytica alcohol dehydrogenase, putative 0.0256 0.0987 0.4291
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.0189
Leishmania major cytochrome p450-like protein 0.0047 0.0121 0.0637
Echinococcus granulosus 7TM GPCR rhodopsin 0.0082 0.027 0.0301
Trypanosoma cruzi sugar transporter, putative 0.0019 0.0006 0.0023
Brugia malayi lactoylglutathione lyase 0.0374 0.1475 0.1474
Leishmania major prostaglandin f synthase, putative 0.0471 0.1878 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0123 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0106 0.0563
Echinococcus multilocularis aldo keto reductase 0.0471 0.1878 0.2621
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Schistosoma mansoni peroxidasin 0.1741 0.7135 0.7134
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0033 0.0066 0.015
Echinococcus multilocularis solute carrier family 22 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Plasmodium falciparum aldo-keto reductase, putative 0.0256 0.0987 0.6687
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.0049 0.0047
Echinococcus multilocularis 0.0048 0.0128 0.0176
Trypanosoma brucei prostaglandin f synthase 0.0471 0.1878 1
Schistosoma mansoni cytochrome P450 0.0047 0.0121 0.0119
Trichomonas vaginalis glucose transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0097
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0103 0.0382
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.008 0.0413
Loa Loa (eye worm) RecQ helicase 0.0049 0.0131 0.0125
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Schistosoma mansoni hypothetical protein 0.0082 0.027 0.0268
Echinococcus granulosus dro:myosuppressin receptor 0.0082 0.027 0.0301
Entamoeba histolytica aldose reductase, putative 0.0471 0.1878 0.8231
Entamoeba histolytica alcohol dehydrogenase, putative 0.0256 0.0987 0.4291
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0034
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0082 0.027 0.0268
Schistosoma mansoni sugar transporter 0.0019 0.0006 0.0004
Echinococcus granulosus ecdysone induced protein 78C 0.0106 0.0366 0.0411
Trypanosoma cruzi hypothetical protein, conserved 0.0354 0.1393 0.7412
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.008 0.0413
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1045 0.2443
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0053 0.0147 0.0141
Onchocerca volvulus 0.0471 0.1878 0.1873
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0037 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0106 0.0366 0.0364
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0011 0.0009
Mycobacterium ulcerans hypothetical protein 0.0021 0.0017 0.0077
Onchocerca volvulus 0.0082 0.027 0.0263
Echinococcus multilocularis dna polymerase kappa 0.0043 0.0106 0.0145
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0161 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0023
Schistosoma mansoni follistatin 0.002 0.0011 0.0009
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0047 0.0121 0.0637
Onchocerca volvulus 0.0082 0.027 0.0263
Mycobacterium tuberculosis Conserved protein 0.0086 0.0286 0.1515
Schistosoma mansoni tyrosine kinase 0.0051 0.0139 0.0137
Echinococcus granulosus protein jagged 1 0.0339 0.1332 0.1499
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0099 0.0109
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0135 0.015
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0106 0.0563
Echinococcus granulosus thyroid hormone receptor alpha 0.005 0.0135 0.015
Brugia malayi Melatonin receptor type 1A 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.2279 0.5335
Echinococcus granulosus acetylcholinesterase 0.0197 0.0744 0.0836
Loa Loa (eye worm) neuropeptide F receptor 0.0082 0.027 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0106 0.0563
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0029 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0286 0.0666
Echinococcus multilocularis fatty acid binding protein FABP2 0.0036 0.0077 0.0105
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0034
Onchocerca volvulus Peroxidasin homolog 0.1739 0.7127 0.7125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0033 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0073 0.0166
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0082 0.027 0.0374
Brugia malayi EGF-like domain containing protein 0.0339 0.1332 0.1331
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0069 0.0453
Schistosoma mansoni opsin-like receptor 0.0082 0.027 0.0268
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0034
Brugia malayi Protein kinase domain containing protein 0.0042 0.0101 0.0099
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0047 0.0121 0.0637
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Brugia malayi putative neuropeptide receptor NPR1 0.0082 0.027 0.0268
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0029 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0029 0.0182
Brugia malayi GCC2 and GCC3 family protein 0.0339 0.1332 0.1331
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0028 0.0044 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0156
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0053 0.0147 0.034
Trypanosoma cruzi aldo/keto reductase, putative 0.0471 0.1878 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0135 0.0133
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0103 0.0236
Schistosoma mansoni loxhd1 0.0041 0.0099 0.0097
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0661 0.1544
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.0029 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0063 0.0334
Echinococcus multilocularis neuropeptide receptor A26 0.1619 0.6632 0.926
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0156
Brugia malayi Doublecortin family protein 0.0041 0.0099 0.0097
Schistosoma mansoni hypothetical protein 0.0082 0.027 0.0268
Schistosoma mansoni steroid hormone receptor ad4bp 0.0106 0.0366 0.0364
Loa Loa (eye worm) runx1 0.0064 0.0194 0.0188
Onchocerca volvulus 0.0046 0.012 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0106 0.0366 0.0364
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0047 0.0121 0.0637
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0127 0.0455 0.0511
Brugia malayi Heterochromatin protein 1 0.0088 0.0291 0.0289
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0083 0.0431
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0661 0.1544
Onchocerca volvulus Putative protein 0.0086 0.0286 0.028
Trypanosoma brucei sugar transporter, putative 0.0019 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Mycobacterium ulcerans sugar transporter 0.0019 0.0006 0.0023
Echinococcus multilocularis 6 phosphofructokinase 0.0126 0.0448 0.0623
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.0029 0.003
Schistosoma mansoni growth hormone secretagogue receptor 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Trichomonas vaginalis DNA helicase recq1, putative 0.0049 0.0131 0.0303
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0297 0.0332
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0026 0.0037 0.0039
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0224 0.0855 0.0853
Giardia lamblia Aldose reductase 0.0471 0.1878 0.8242
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0029 0.0182
Echinococcus multilocularis microtubule associated protein 2 0.0721 0.2911 0.4063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.006
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Trypanosoma cruzi glucose transporter, putative 0.0019 0.0006 0.0023
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0133 0.0479 0.0537
Loa Loa (eye worm) hypothetical protein 0.2433 1 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Echinococcus granulosus twitchin 0.0032 0.006 0.0065
Onchocerca volvulus 0.2209 0.9073 0.9072
Brugia malayi Steroid receptor seven-up type 2 0.0106 0.0366 0.0364
Brugia malayi glutathione reductase 0.0051 0.0141 0.0139
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0029 0.0063
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0033 0.0066 0.0064
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.006
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0103 0.0141
Schistosoma mansoni hypothetical protein 0.0224 0.0855 0.0853
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0103 0.0236
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0106 0.0553
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.001
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.008 0.0413
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0224 0.0855 0.0853
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0029 0.0063
Onchocerca volvulus 0.0082 0.027 0.0263
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0019 0.0093
Loa Loa (eye worm) hypothetical protein 0.004 0.0094 0.0087
Echinococcus multilocularis transfer RNA-Lys 0.0151 0.0552 0.0768
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0117 0.0413 0.2132
Echinococcus granulosus hypothetical protein 0.0471 0.1878 0.2114
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0029 0.0027
Brugia malayi hypothetical protein 0.0683 0.2755 0.2754
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0106 0.0366 0.0411
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0042 0.0103 0.0101
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0083 0.0271 0.0269
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0006
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0183 0.0252
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0339 0.1332 0.1327
Brugia malayi Animal haem peroxidase family protein 0.1733 0.71 0.71
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0568 0.2279 1
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0058 0.0167 0.023
Echinococcus multilocularis slit 2 protein 0.0339 0.1332 0.1858
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0051 0.014 0.0193
Loa Loa (eye worm) oxidoreductase 0.0046 0.012 0.0114
Schistosoma mansoni BC026374 protein (S09 family) 0.0033 0.0066 0.0064
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0094 0.0317 0.0315
Schistosoma mansoni neuropeptide receptor 0.0082 0.027 0.0268
Echinococcus multilocularis fibropellin Ia 0.0339 0.1332 0.1858
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0042
Toxoplasma gondii aldose reductase, putative 0.0471 0.1878 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0106 0.0366 0.0364
Loa Loa (eye worm) hypothetical protein 0.0056 0.016 0.0153
Brugia malayi phosphofructokinase 0.0126 0.0448 0.0446
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0106 0.0366 0.0364
Echinococcus granulosus lamin dm0 0.0119 0.0423 0.0474
Brugia malayi hypothetical protein 0.0033 0.0066 0.0064
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0069 0.0453
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0471 0.1878 0.1877
Loa Loa (eye worm) neuropeptide F receptor 0.0082 0.027 0.0263
Onchocerca volvulus Putative organic anion transporter 0.0029 0.0049 0.0042
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0082 0.027 0.0374
Echinococcus multilocularis synaptic vesicle 2 protein 0.0019 0.0006 0.0006
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0082 0.027 0.0268
Schistosoma mansoni aldo-keto reductase 0.0471 0.1878 0.1877
Brugia malayi EGF-like domain containing protein 0.0339 0.1332 0.1331
Onchocerca volvulus Netrin receptor homolog 0.0048 0.0128 0.0122
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0106 0.0553
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0047 0.0121 0.0637
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0069 0.0231
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0132 0.0475 0.0473
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0246 0.0948 0.1066
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0047 0.0121 0.0637
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.0448 0.0442
Echinococcus multilocularis aldo keto reductase 0.0471 0.1878 0.2621
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0082 0.027 0.0268
Loa Loa (eye worm) sugar transporter 0.0051 0.014 0.0134
Brugia malayi Major Facilitator Superfamily protein 0.0019 0.0006 0.0004
Echinococcus multilocularis lamin dm0 0.0119 0.0423 0.0587
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0106 0.0553
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0047 0.0121 0.0637
Onchocerca volvulus 0.0256 0.0987 0.0981
Echinococcus granulosus tm gpcr rhodopsin 0.0082 0.027 0.0301
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.006
Leishmania major cathepsin L-like protease 0.0057 0.0166 0.0872
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0224 0.0855 0.0853
Echinococcus multilocularis epidermal growth factor receptor 0.0085 0.0279 0.0387
Schistosoma mansoni neuroligin 3 (S09 family) 0.0033 0.0066 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0661 0.1544
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0012 0.001
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0471 0.1878 0.1877
Echinococcus granulosus Tolloid protein 1 0.0112 0.039 0.0438
Echinococcus multilocularis FTZ F1 alpha 0.0106 0.0366 0.0509
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0374 0.1475 0.7852
Onchocerca volvulus Slit protein homolog 0.0339 0.1332 0.1327
Onchocerca volvulus 0.0053 0.0147 0.0141
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.2279 0.5335
Loa Loa (eye worm) hypothetical protein 0.0354 0.1393 0.1387
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0047 0.0121 0.0637
Brugia malayi EGF-like domain containing protein 0.0339 0.1332 0.1331
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0026 0.0037 0.0035
Schistosoma mansoni tyrosine kinase 0.0083 0.0271 0.0269
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0053 0.0147 0.0164
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Brugia malayi G-protein coupled receptor 0.0082 0.027 0.0268
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0047 0.0121 0.0637
Onchocerca volvulus Protein ultraspiracle homolog 0.0106 0.0366 0.036
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0082 0.027 0.0268
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0471 0.1878 0.4397
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.016 0.0158
Mycobacterium tuberculosis Probable dehydrogenase 0.0117 0.0413 0.2193
Onchocerca volvulus 0.0046 0.012 0.0114
Brugia malayi Cytochrome P450 family protein 0.0152 0.0557 0.0555
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0019 0.0006 0.0006
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.0083 0.0271 0.0265
Leishmania major hypothetical protein, conserved 0.0019 0.0006 0.0023
Giardia lamblia Aldose reductase 0.0471 0.1878 0.8242
Echinococcus granulosus microtubule associated protein 2 0.0721 0.2911 0.3278
Brugia malayi G-protein coupled receptor 0.0082 0.027 0.0268
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0141 0.0194
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0094 0.0317 0.044
Loa Loa (eye worm) hypothetical protein 0.0471 0.1878 0.1873
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0047 0.0121 0.0637
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0082 0.027 0.0374
Schistosoma mansoni amine GPCR 0.0082 0.027 0.0268
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0053 0.0147 0.0774
Brugia malayi FAD binding domain containing protein 0.0028 0.0044 0.0042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0106 0.0553
Brugia malayi Uncoordinated protein 44 0.0042 0.0101 0.0099
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Trypanosoma brucei DNA polymerase IV, putative 0.0036 0.0077 0.0412
Echinococcus granulosus neural cadherin 0.0339 0.1332 0.1499
Schistosoma mansoni nuclear hormone receptor 0.005 0.0135 0.0133
Onchocerca volvulus 0.0151 0.0552 0.0546
Echinococcus granulosus tissue type plasminogen activator 0.0354 0.1393 0.1567
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0029 0.0055
Brugia malayi Animal haem peroxidase family protein 0.1733 0.71 0.71
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.005 0.0135 0.0133
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0106 0.0366 0.0509
Schistosoma mansoni tyrosine kinase 0.0083 0.0271 0.0269
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0029 0.0038
Echinococcus granulosus G protein coupled receptor 139 0.0082 0.027 0.0301
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0029 0.0049 0.0053
Brugia malayi Protein cec-1. 0.0024 0.0029 0.0027
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0019 0.0006 0.0004
Echinococcus multilocularis fibrillin 1 0.0112 0.039 0.0543
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.008 0.0078
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0082 0.027 0.0374
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0082 0.027 0.0374
Brugia malayi 6-phosphofructokinase 0.0126 0.0448 0.0446
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.0448 0.1908
Plasmodium vivax hexose transporter 0.0051 0.014 0.0936
Echinococcus multilocularis carboxylesterase 5A 0.0197 0.0744 0.1036
Schistosoma mansoni biogenic amine (5HT) receptor 0.0082 0.027 0.0268
Schistosoma mansoni organic anion transporter 0.0029 0.0049 0.0047
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0082 0.027 0.0268
Plasmodium vivax glutathione reductase, putative 0.0051 0.0141 0.0943
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0033 0.0066 0.009
Onchocerca volvulus Neuropeptide F receptor homolog 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0106 0.0366 0.036
Trypanosoma cruzi cruzipain precursor, putative 0.0057 0.0166 0.0872
Onchocerca volvulus 0.0046 0.012 0.0114
Schistosoma mansoni ap endonuclease 0.0037 0.008 0.0078
Schistosoma mansoni hypothetical protein 0.0354 0.1393 0.1391
Leishmania major hypothetical protein, conserved 0.0354 0.1393 0.7412
Brugia malayi prostaglandin transporter 0.0029 0.0049 0.0047
Loa Loa (eye worm) inositol-1 0.0042 0.0103 0.0096
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0027
Echinococcus granulosus para nitrobenzyl esterase 0.0033 0.0066 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0033 0.0073
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0661 0.1544
Loa Loa (eye worm) hypothetical protein 0.0224 0.0855 0.0849
Brugia malayi Animal haem peroxidase family protein 0.1733 0.71 0.71
Echinococcus granulosus 7tm_1 domain containing protein 0.0082 0.027 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0286 0.0666
Toxoplasma gondii facilitative glucose transporter GT1 0.0051 0.014 0.0735
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0019 0.0006 0.0023
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0051 0.014 0.0155
Plasmodium vivax glyoxalase I, putative 0.0086 0.0286 0.193
Leishmania major DNA polymerase kappa, putative 0.0022 0.0019 0.0093
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0017 0.0077
Schistosoma mansoni sugar transporter 0.0019 0.0006 0.0004
Echinococcus multilocularis aldehyde reductase 0.0215 0.082 0.1142
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Echinococcus multilocularis musashi 0.0119 0.0423 0.0587
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0471 0.1878 0.2114
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0147 0.034
Leishmania major cytochrome P450 reductase, putative 0.0025 0.0031 0.0153
Brugia malayi notch-like transmembrane receptor 0.0339 0.1332 0.1331
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0106 0.0366 0.036
Toxoplasma gondii glyoxalase family protein 0.0086 0.0286 0.1515
Brugia malayi Serotonin receptor 0.0082 0.027 0.0268
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0029 0.0027
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0112 0.039 0.0384
Trichomonas vaginalis aldo/keto reductase, putative 0.0471 0.1878 0.4397
Onchocerca volvulus 0.0354 0.1393 0.1387
Schistosoma mansoni aryl hydrocarbon receptor 0.0204 0.0771 0.0769
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Onchocerca volvulus 0.0082 0.027 0.0263
Onchocerca volvulus 0.0046 0.012 0.0114
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0012 0.0011
Onchocerca volvulus 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Loa Loa (eye worm) hypothetical protein 0.0106 0.0366 0.036
Brugia malayi nuclear receptor NHR-88 0.0106 0.0366 0.0364
Schistosoma mansoni hypothetical protein 0.0339 0.1332 0.1331
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0002 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0156
Echinococcus multilocularis somatostatin receptor 0.0082 0.027 0.0374
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0297 0.0295
Giardia lamblia Hexose transporter 0.0019 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Loa Loa (eye worm) hypothetical protein 0.0112 0.039 0.0384
Mycobacterium leprae conserved hypothetical protein 0.0086 0.0286 0.1449
Echinococcus multilocularis neuroligin 0.0033 0.0066 0.009
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0019 0.0103
Echinococcus granulosus aryl hydrocarbon receptor 0.0053 0.0147 0.0164
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0183 0.0176
Brugia malayi nuclear hormone receptor family member nhr-6 0.005 0.0135 0.0133
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1045 0.2443
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0123 0.0642
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0147 0.034
Onchocerca volvulus 0.0119 0.0423 0.0416
Loa Loa (eye worm) hypothetical protein 0.0106 0.0366 0.036
Loa Loa (eye worm) hypothetical protein 0.0032 0.0063 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0047 0.0121 0.0637
Echinococcus multilocularis fmrfamide receptor 0.0082 0.027 0.0374
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0082 0.027 0.0374
Onchocerca volvulus 0.0339 0.1332 0.1327
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0082 0.027 0.0263
Echinococcus granulosus peptide allatostatin:somatostatin 0.0082 0.027 0.0301
Schistosoma mansoni tyrosine kinase 0.0051 0.0139 0.0137
Onchocerca volvulus Neurogenic locus notch homolog 0.034 0.1334 0.1328
Trichomonas vaginalis chromobox protein, putative 0.0088 0.0291 0.0677
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0017 0.0077
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0034
Echinococcus granulosus fibropellin Ia 0.0339 0.1332 0.1499
Toxoplasma gondii sugar transporter ST1 0.0019 0.0006 0.0023
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.002 0.0011 0.0009
Echinococcus multilocularis Protein lozenge 0.0064 0.0194 0.0268
Brugia malayi Cadherin domain containing protein 0.0339 0.1332 0.1331
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0064 0.0193 0.0187
Leishmania major glucose transporter, lmgt1 0.0019 0.0006 0.0023
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0036 0.0077 0.0071
Brugia malayi Nuclear hormone receptor E75 0.005 0.0135 0.0133
Brugia malayi jmjC domain containing protein 0.0061 0.0183 0.0181
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0042
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0012 0.0044
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0029 0.0063
Echinococcus multilocularis BC026374 protein (S09 family) 0.0033 0.0066 0.009
Onchocerca volvulus 0.0471 0.1878 0.1873
Schistosoma mansoni biogenic amine receptor 0.0082 0.027 0.0268
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0028 0.0044 0.0233
Onchocerca volvulus 0.0471 0.1878 0.1873
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.027 0.0268
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0103 0.0537
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0126 0.0448 0.2378
Entamoeba histolytica hypothetical protein 0.0024 0.0029 0.0055
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.027 0.0374
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Loa Loa (eye worm) carboxylesterase 0.0197 0.0744 0.0738
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0106 0.0366 0.0364
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0106 0.0366 0.0411
Echinococcus multilocularis thyroid hormone receptor alpha 0.0237 0.0911 0.1269
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0123 0.0653
Loa Loa (eye worm) hypothetical protein 0.0345 0.1355 0.135
Loa Loa (eye worm) TK/INSR protein kinase 0.0051 0.0139 0.0132
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0082 0.027 0.0268
Schistosoma mansoni thyroid hormone receptor 0.0237 0.0911 0.0909
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0051 0.014 0.0155
Echinococcus multilocularis G protein coupled receptor 139 0.0082 0.027 0.0374
Entamoeba histolytica hypothetical protein 0.0024 0.0029 0.0055
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0029 0.0027
Brugia malayi putative neuropeptide receptor 0.0082 0.027 0.0268
Onchocerca volvulus 0.0082 0.027 0.0263
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.027 0.0301
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0123 0.0642
Onchocerca volvulus 0.002 0.0011 0.0004
Echinococcus granulosus geminin 0.0143 0.052 0.0584
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0106 0.0366 0.036
Brugia malayi cytochrome P450 0.0047 0.0121 0.0119
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0214 0.0814 0.1135
Mycobacterium leprae Conserved hypothetical protein 0.0215 0.082 0.4313
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0028 0.0044 0.0058
Schistosoma mansoni chromobox protein 0.0088 0.0291 0.0289
Schistosoma mansoni retinoic acid receptor RXR 0.0209 0.0792 0.0791
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0471 0.1878 0.2114
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0037 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0063 0.0334
Brugia malayi Nuclear hormone receptor E75 0.005 0.0135 0.0133
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.027 0.0374
Loa Loa (eye worm) hypothetical protein 0.0029 0.0049 0.0042
Brugia malayi AKH receptor 0.0082 0.027 0.0268
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0029 0.0063
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0028 0.0044 0.0223
Echinococcus granulosus notch 0.0339 0.1332 0.1499
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0277 0.1076 0.5692
Schistosoma mansoni inositol monophosphatase 0.0042 0.0103 0.0101
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.027 0.1045 0.1039
Brugia malayi 6-phosphofructokinase 0.0126 0.0449 0.0447
Echinococcus granulosus carboxylesterase 5A 0.0197 0.0744 0.0836
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.008 0.0182
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0051 0.0139 0.0191
Brugia malayi G protein-coupled receptor 0.0082 0.027 0.0268
Echinococcus multilocularis Immunoglobulin 0.0025 0.0033 0.0043
Leishmania major cytochrome p450-like protein 0.0047 0.0121 0.0637
Trichomonas vaginalis set domain proteins, putative 0.1049 0.4269 1
Echinococcus granulosus RUN 0.0041 0.0099 0.0109
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0051 0.014 0.0193
Onchocerca volvulus 0.0046 0.012 0.0114
Brugia malayi Protein kinase domain containing protein 0.0051 0.0139 0.0137
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0106 0.0366 0.0364
Echinococcus multilocularis fmrfamide receptor 0.0082 0.027 0.0374
Brugia malayi Carboxylesterase family protein 0.0197 0.0744 0.0742
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0069 0.4594
Onchocerca volvulus 0.1049 0.4271 0.4267
Loa Loa (eye worm) hypothetical protein 0.0028 0.0044 0.0037
Echinococcus multilocularis neurogenic locus protein delta 0.0339 0.1332 0.1858
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0086 0.0286 0.1515
Brugia malayi Death domain containing protein 0.0042 0.0101 0.0099
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0082 0.027 0.0268
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0085 0.0279 0.0312
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0069 0.0156
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.0049 0.0047
Loa Loa (eye worm) DR-78 0.005 0.0135 0.0129
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.0049 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0661 0.1544
Loa Loa (eye worm) hypothetical protein 0.0058 0.0167 0.0161
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0033 0.0031
Echinococcus granulosus acetylcholinesterase 0.0197 0.0744 0.0836
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Loa Loa (eye worm) hypothetical protein 0.0137 0.0495 0.0489
Toxoplasma gondii protease inhibitor PI2 0.002 0.0011 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0132 0.0475 0.0473
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0101 0.0095
Plasmodium falciparum cysteine repeat modular protein 1 0.0354 0.1393 0.9439
Onchocerca volvulus 0.0082 0.027 0.0263
Onchocerca volvulus 0.0471 0.1878 0.1873
Trichomonas vaginalis hypothetical protein 0.0024 0.0029 0.0063
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0002 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.027 0.0268
Loa Loa (eye worm) intermediate filament protein 0.0119 0.0423 0.0416
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0094 0.0216
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0029 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1045 0.2443
Schistosoma mansoni nuclear hormone receptor 0.005 0.0135 0.0133
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0051 0.0139 0.0154
Onchocerca volvulus 0.0041 0.0099 0.0092
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.002 0.0108
Schistosoma mansoni RAR-like nuclear receptor 0.0106 0.0366 0.0364
Schistosoma mansoni neuropeptide receptor 0.0082 0.027 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Echinococcus multilocularis protein jagged 2 0.0339 0.1332 0.1858
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0069 0.0356
Echinococcus multilocularis General substrate transporter 0.0032 0.0062 0.0084
Loa Loa (eye worm) nuclear receptor nhr-7B 0.005 0.0135 0.0129
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0053 0.0147 0.0774
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Loa Loa (eye worm) agrin synaptic family protein 0.002 0.0011 0.0004
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0028 0.0044 0.0233
Loa Loa (eye worm) hypothetical protein 0.0512 0.2047 0.2042
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0083 0.0442
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Echinococcus multilocularis chromobox protein 1 0.0088 0.0291 0.0404
Trichomonas vaginalis adenylate cyclase, putative 0.0053 0.0147 0.034
Brugia malayi GnHR receptor homolog 0.0082 0.027 0.0268
Echinococcus multilocularis nuclear receptor nhr 48 0.005 0.0135 0.0186
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0183 0.0181
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0029 0.0027
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0086 0.0286 0.0284
Schistosoma mansoni notch 0.0339 0.1332 0.1331
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.0106 0.0366 0.036
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0058 0.0167 0.016
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0017 0.0077
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.006
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0183 0.0252
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0023
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Toxoplasma gondii exonuclease III APE 0.0037 0.008 0.0413
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Onchocerca volvulus 0.1733 0.71 0.7099
Brugia malayi Pre-SET motif family protein 0.0132 0.0475 0.0473
Schistosoma mansoni rab6-interacting 0.0041 0.0099 0.0097
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0085 0.044
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.001
Schistosoma mansoni hypothetical protein 0.0042 0.0101 0.0099
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0053 0.0119
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0123 0.0121
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0028 0.0044 0.0223
Echinococcus multilocularis GPCR, family 2 0.0026 0.0037 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.027 0.0268
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0047 0.0121 0.0637
Onchocerca volvulus 0.0082 0.027 0.0263
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0037 0.0195
Echinococcus granulosus orexin receptor type 2 0.0082 0.027 0.0301
Echinococcus multilocularis fat cadherin tumor suppressor 0.0339 0.1332 0.1858
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0047 0.0121 0.0637
Entamoeba histolytica hypothetical protein 0.0133 0.0479 0.2043
Echinococcus multilocularis serotonin receptor 0.0082 0.027 0.0374
Schistosoma mansoni hypothetical protein 0.0026 0.0037 0.0035
Brugia malayi Trypsin family protein 0.0224 0.0855 0.0853
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0053 0.0147 0.034
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Schistosoma mansoni hypothetical protein 0.0143 0.052 0.0518
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.002 0.0011 0.0004
Loa Loa (eye worm) acetylcholinesterase 1 0.0197 0.0744 0.0738
Schistosoma mansoni organic anion transporter 0.0029 0.0049 0.0047
Onchocerca volvulus 0.0119 0.0423 0.0416
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0153 0.0561 0.0781
Mycobacterium leprae Conserved hypothetical protein 0.0047 0.0121 0.0564
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1045 0.2443
Brugia malayi sulfakinin receptor protein 0.0082 0.027 0.0268
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0069 0.0293
Schistosoma mansoni glucose transport protein 0.0051 0.014 0.0138
Echinococcus granulosus tm gpcr rhodopsin 0.0082 0.027 0.0301
Mycobacterium leprae Possible oxidoreductase 0.0256 0.0987 0.5214
Echinococcus granulosus insulin receptor 0.0051 0.0139 0.0154
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Trypanosoma cruzi aldo/keto reductase, putative 0.0256 0.0987 0.5251
Loa Loa (eye worm) transcription factor SMAD2 0.0108 0.0373 0.0367
Brugia malayi Dopamine receptor protein 2 0.0082 0.027 0.0268
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0106 0.0366 0.0509
Loa Loa (eye worm) hypothetical protein 0.0055 0.0158 0.0151
Echinococcus granulosus neuropeptide receptor 0.0082 0.027 0.0301
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0017 0.0014
Echinococcus granulosus neuropeptides capa receptor 0.0082 0.027 0.0301
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0166 0.0872
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0106 0.0366 0.036
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0029 0.0027
Brugia malayi Blistered cuticle protein 3 0.1733 0.71 0.71
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Mycobacterium leprae Possible regulatory protein 0.0053 0.0147 0.0703
Schistosoma mansoni glucose transporter 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Echinococcus multilocularis serotonin receptor 0.0082 0.027 0.0374
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0106 0.0366 0.036
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0047 0.0121 0.0637
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0025 0.0033 0.0043
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.0106 0.0243
Brugia malayi EGF-like domain containing protein 0.0339 0.1332 0.1331
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0106 0.0366 0.0509
Brugia malayi EGF-like domain containing protein 0.0339 0.1332 0.1331
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0167 0.0386
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0028 0.0044 0.0233
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0471 0.1878 0.2114
Echinococcus multilocularis fatty acid binding protein FABP2 0.0036 0.0077 0.0105
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Echinococcus multilocularis Mastin 0.0224 0.0855 0.1192
Echinococcus multilocularis G-protein coupled receptor, putative 0.0082 0.027 0.0374
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.008 0.0526
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0082 0.027 0.0263
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0051 0.014 0.0193
Echinococcus multilocularis g protein coupled receptor 0.0082 0.027 0.0374
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0012 0.0068
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0106 0.0366 0.0364
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0059 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.001
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.0037 0.0081
Brugia malayi Trypsin family protein 0.0224 0.0855 0.0853
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Trichomonas vaginalis DNA helicase recq, putative 0.0049 0.0131 0.0303
Brugia malayi Serotonin receptor 0.0082 0.027 0.0268
Echinococcus multilocularis neurogenic locus notch protein 4 0.0339 0.1332 0.1858
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0033 0.0073
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0006 0.0023
Onchocerca volvulus 0.0118 0.0417 0.0411
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0082 0.027 0.0374
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0106 0.0366 0.0364
Mycobacterium ulcerans hypothetical protein 0.0086 0.0286 0.1515
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0106 0.0366 0.0411
Brugia malayi Cadherin domain containing protein 0.0339 0.1332 0.1331
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0183 0.0181
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Schistosoma mansoni laminin gamma-3 chain 0.0339 0.1332 0.1331
Echinococcus granulosus Sugar transporter ERD6 protein 0.0019 0.0006 0.0005
Onchocerca volvulus 0.0224 0.0855 0.0849
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0057 0.0166 0.0882
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.002 0.0011 0.0046
Loa Loa (eye worm) hypothetical protein 0.0224 0.0855 0.0849
Schistosoma mansoni hypothetical protein 0.0047 0.0121 0.0119
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Echinococcus multilocularis neuropeptide receptor 0.0082 0.027 0.0374
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0117 0.0413 0.2193
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.027 0.0301
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0047 0.0121 0.0637
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0021 0.0017 0.0077
Echinococcus granulosus biogenic amine 5HT receptor 0.0082 0.027 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0053 0.0119
Echinococcus granulosus aldo keto reductase 0.0471 0.1878 0.2114
Trichomonas vaginalis glucose transporter, putative 0.0019 0.0006 0.001
Echinococcus granulosus g protein coupled receptor 0.0082 0.027 0.0301
Loa Loa (eye worm) hypothetical protein 0.0026 0.0037 0.003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0023
Onchocerca volvulus 0.0029 0.0049 0.0042
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0141 0.0741
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Echinococcus granulosus GPCR family 2 0.0026 0.0037 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0448 0.1045
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0448 0.1045
Schistosoma mansoni septate junction protein 0.0339 0.1332 0.1331
Onchocerca volvulus Peroxidase homolog 0.1733 0.71 0.7099
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0256 0.0987 0.0981
Loa Loa (eye worm) blistered cuticle protein 3 0.1733 0.71 0.7099
Loa Loa (eye worm) FAD binding domain-containing protein 0.0028 0.0044 0.0037
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0082 0.027 0.0263
Mycobacterium ulcerans hypothetical protein 0.0086 0.0286 0.1515
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0086 0.0286 0.1515
Onchocerca volvulus 0.0033 0.0066 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.0189
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0017 0.0077
Brugia malayi Calcitonin receptor-like protein seb-1 0.0083 0.0271 0.0269
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0006 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1045 0.2443
Onchocerca volvulus 0.0033 0.0066 0.006
Onchocerca volvulus 0.0029 0.0049 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0661 0.1544
Loa Loa (eye worm) carboxylesterase 0.0033 0.0066 0.006
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Schistosoma mansoni cell polarity protein 0.0339 0.1332 0.1331
Loa Loa (eye worm) TK/ROR protein kinase 0.0362 0.1427 0.1422
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.008 0.0073
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0047 0.0121 0.0637
Echinococcus multilocularis neural cadherin 0.0339 0.1332 0.1858
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0123 0.0168
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.008 0.0424
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0171 0.0635 0.3372
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.2279 0.5335
Echinococcus multilocularis neuropeptide s receptor 0.1619 0.6632 0.926
Echinococcus granulosus glycoprotein Antigen 5 0.0224 0.0855 0.0962
Brugia malayi Fibronectin type III domain containing protein 0.0025 0.0033 0.0031
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0471 0.1878 0.2114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0044 0.0099
Loa Loa (eye worm) hypothetical protein 0.0042 0.0101 0.0095
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0034
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.005 0.0135 0.0133
Brugia malayi nuclear hormone receptor 0.0106 0.0366 0.0364
Brugia malayi hypothetical protein 0.005 0.0135 0.0133
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0277 0.1076 0.5726
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0224 0.0855 0.0962
Brugia malayi Trypsin-like protease protein 5 0.0224 0.0855 0.0853
Brugia malayi Animal haem peroxidase family protein 0.1733 0.71 0.71
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0012 0.0053
Echinococcus granulosus aldo keto reductase 0.0471 0.1878 0.2114
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0135 0.0129
Trypanosoma brucei glucose transporter 2A 0.0019 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Trypanosoma cruzi MFS transporter, putative 0.0029 0.0049 0.0249
Schistosoma mansoni opsin-like receptor 0.0082 0.027 0.0268
Onchocerca volvulus Peroxidasin homolog 0.1739 0.7127 0.7125
Onchocerca volvulus 0.1733 0.71 0.7099
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Echinococcus granulosus somatostatin receptor 0.0082 0.027 0.0301
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0047 0.0121 0.0637
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0047 0.0121 0.0637
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0027
Brugia malayi Latrophilin receptor protein 2 0.0026 0.0037 0.0035
Brugia malayi hypothetical protein 0.0056 0.016 0.0158
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0017 0.0077
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0256 0.0987 0.5251
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0029 0.0143
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0073 0.0377
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0132 0.0475 0.0661
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0029 0.0182
Loa Loa (eye worm) TK/KIN16 protein kinase 0.041 0.1627 0.1622
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0044 0.0099
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.006
Brugia malayi hypothetical protein 0.0019 0.0006 0.0004
Echinococcus granulosus death domain containing protein 0.0042 0.0101 0.0112
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0135 0.0186
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0106 0.0563
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0374 0.1475 0.147
Loa Loa (eye worm) hypothetical protein 0.0117 0.0414 0.0407
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0047 0.0121 0.0637
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0019 0.0006 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.014 0.0323
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.027 0.0301
Onchocerca volvulus 0.0339 0.1332 0.1327
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0277 0.1076 0.5726
Echinococcus granulosus neurogenic locus notch protein 0.0339 0.1332 0.1499
Brugia malayi Nuclear hormone receptor-like 1 0.0106 0.0366 0.0364
Brugia malayi ORL1-like opioid receptor 0.0082 0.027 0.0268
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0471 0.1878 0.4397
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0029 0.0049 0.0065
Echinococcus multilocularis glycoprotein Antigen 5 0.0224 0.0855 0.1192
Trypanosoma brucei THT1 - hexose transporter, putative 0.0019 0.0006 0.0034
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0047 0.0121 0.0637
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Echinococcus granulosus solute carrier family 22 0.0019 0.0006 0.0005
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0471 0.1878 0.2114
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0471 0.1878 1
Loa Loa (eye worm) TYRA-2 protein 0.0082 0.027 0.0263
Echinococcus granulosus peroxidasin 0.1747 0.7161 0.8067
Brugia malayi tailless protein 0.005 0.0135 0.0133
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0141 0.0943
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0471 0.1878 0.1877
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0141 0.0135
Brugia malayi hypothetical protein 0.0132 0.0476 0.0474
Schistosoma mansoni coup transcription factor 0.0106 0.0366 0.0364
Plasmodium vivax flavodoxin domain containing protein 0.0025 0.0031 0.0195
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0026 0.0037 0.0049
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Trypanosoma cruzi major cysteine proteinase, putative 0.0045 0.0115 0.0601
Echinococcus multilocularis neurogenic locus notch protein 0.0339 0.1332 0.1858
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0047 0.0121 0.0637
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0166 0.0872
Echinococcus granulosus allatostatin A receptor 0.0082 0.027 0.0301
Echinococcus multilocularis neuropeptides capa receptor 0.0082 0.027 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0083 0.0189
Echinococcus granulosus biogenic amine 5HT receptor 0.0082 0.027 0.0301
Schistosoma mansoni alpha-1 adrenergic receptor 0.0082 0.027 0.0268
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0224 0.0855 0.1192
Schistosoma mansoni rab6-interacting 0.0041 0.0099 0.0097
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0471 0.1878 0.2621
Loa Loa (eye worm) hypothetical protein 0.0056 0.016 0.0153
Echinococcus multilocularis enteropeptidase 0.0224 0.0855 0.1192
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0017 0.0077
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0354 0.1393 0.9439
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0106 0.0563
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.2279 0.5335
Brugia malayi Carboxylesterase family protein 0.0033 0.0066 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0106 0.0366 0.0364
Echinococcus granulosus solute carrier family 22 0.0019 0.0006 0.0005
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0056 0.016 0.0153
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0106 0.0366 0.0364
Echinococcus granulosus dna polymerase kappa 0.0043 0.0106 0.0117
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Echinococcus multilocularis orexin receptor type 2 0.0082 0.027 0.0374
Onchocerca volvulus Peroxidase homolog 0.1733 0.71 0.7099
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0029 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.027 0.0268
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0021 0.0017 0.0077
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0029 0.0063
Schistosoma mansoni notch 0.0339 0.1332 0.1331
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0082 0.027 0.0301
Leishmania major protein kinase, putative 0.0053 0.0147 0.0774
Brugia malayi Peroxidasin 0.1747 0.7161 0.7161
Echinococcus granulosus solute carrier family 22 0.0019 0.0006 0.0005
Echinococcus multilocularis expressed protein 0.002 0.0011 0.0012
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0103 0.0537
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0025 0.0031 0.0067
Plasmodium vivax aldehyde reductase, putative 0.0256 0.0987 0.6687
Echinococcus multilocularis chromobox protein 1 0.0088 0.0291 0.0404
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0106 0.0563
Trypanosoma brucei glucose transporter, putative 0.0019 0.0006 0.0034
Schistosoma mansoni notch 0.0339 0.1332 0.1331
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.027 0.0374
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Onchocerca volvulus 0.0082 0.027 0.0263
Brugia malayi jmjC domain containing protein 0.0061 0.0183 0.0181
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0052 0.0145 0.0762
Schistosoma mansoni neuropeptide receptor 0.0082 0.027 0.0268
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.008 0.0182
Onchocerca volvulus 0.0046 0.012 0.0114
Mycobacterium tuberculosis Probable reductase 0.0117 0.0413 0.2193
Echinococcus granulosus neuropeptide Y receptor 0.0082 0.027 0.0301
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.027 0.0268
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Trichomonas vaginalis spcc417.12 protein, putative 0.0033 0.0066 0.015
Echinococcus multilocularis g-protein coupled receptor 0.0082 0.027 0.0374
Echinococcus granulosus Ankyrin 0.0042 0.0103 0.0114
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.006
Loa Loa (eye worm) hypothetical protein 0.0119 0.0423 0.0416
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.001
Mycobacterium ulcerans oxidoreductase 0.0471 0.1878 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0069 0.0293
Schistosoma mansoni hypothetical protein 0.0143 0.052 0.0518
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.008 0.0413
Loa Loa (eye worm) trypsin family protein 0.0224 0.0855 0.0849
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0082 0.027 0.0374
Loa Loa (eye worm) notch protein 0.0339 0.1332 0.1327
Onchocerca volvulus 0.2433 1 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0012 0.0053
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0135 0.0129
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0083 0.0431
Onchocerca volvulus 0.0118 0.0417 0.0411
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.013 0.0468 0.2481
Mycobacterium tuberculosis Probable oxidoreductase 0.0471 0.1878 1
Brugia malayi hypothetical protein 0.0056 0.016 0.0158
Trypanosoma brucei THT1 - hexose transporter, putative 0.0019 0.0006 0.0034
Brugia malayi M-phase phosphoprotein, mpp8 0.0118 0.0417 0.0415
Schistosoma mansoni tyrosine kinase 0.0085 0.0279 0.0277
Brugia malayi Major Facilitator Superfamily protein 0.0019 0.0006 0.0004
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0224 0.0855 0.0962
Onchocerca volvulus Tyrosine kinase homolog 0.0383 0.1515 0.151
Loa Loa (eye worm) hypothetical protein 0.0118 0.0419 0.0413
Echinococcus multilocularis follistatin 0.002 0.0011 0.0012
Echinococcus granulosus Chromo domain 0.0024 0.0029 0.003
Brugia malayi Calcium binding EGF domain containing protein 0.0112 0.039 0.0389
Brugia malayi polk-prov protein 0.0032 0.0063 0.0061
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.008 0.7692
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0106 0.0366 0.0364
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0069 0.0156
Echinococcus granulosus solute carrier family 22 0.0019 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.0133 0.0479 0.2043
Trichomonas vaginalis glucose transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0053 0.0147 0.0141
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0006 0.0023
Plasmodium falciparum thioredoxin reductase 0.0051 0.0141 0.0943
Plasmodium falciparum hexose transporter 0.0051 0.014 0.0936
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0051 0.014 0.0155
Schistosoma mansoni hypothetical protein 0.0082 0.027 0.0268
Schistosoma mansoni fatty acid binding protein 0.0036 0.0077 0.0075
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0047 0.0121 0.0637
Echinococcus granulosus follistatin 0.002 0.0011 0.001
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0047 0.0121 0.0637
Brugia malayi Muscle positioning protein 4 0.0339 0.1332 0.1331
Mycobacterium ulcerans integral membrane transport protein 0.0019 0.0006 0.0023
Echinococcus granulosus Mastin 0.0224 0.0855 0.0962
Brugia malayi CHD4 protein 0.0024 0.0029 0.0027
Onchocerca volvulus 0.0033 0.0066 0.006
Plasmodium falciparum aldehyde reductase, putative 0.0256 0.0987 0.6687
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Onchocerca volvulus 0.0082 0.027 0.0263
Trichomonas vaginalis aldo/keto reductase, putative 0.0471 0.1878 0.4397
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0047 0.0121 0.0637
Echinococcus granulosus single minded 2 0.0151 0.0552 0.062
Schistosoma mansoni tyrosine kinase 0.0083 0.0271 0.0269
Echinococcus multilocularis protein jagged 1 0.0339 0.1332 0.1858
Brugia malayi hypothetical protein 0.0224 0.0855 0.0853
Echinococcus multilocularis agrin 0.002 0.0011 0.0012
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Loa Loa (eye worm) latrophilin receptor protein 2 0.0026 0.0037 0.003
Echinococcus granulosus g-protein coupled receptor 0.0082 0.027 0.0301
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.2279 0.5335
Brugia malayi hypothetical protein 0.0029 0.0049 0.0047
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0224 0.0855 0.0853
Echinococcus multilocularis neuropeptide receptor 0.0082 0.027 0.0374
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0006 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.2279 0.5335
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0047 0.0121 0.0637
Schistosoma mansoni peroxidasin 0.1733 0.71 0.71
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0029 0.0063
Echinococcus multilocularis Chromo domain 0.0024 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0112 0.039 0.0384
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0297 0.0411
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0256 0.0987 0.5251
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0161 0.0847
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0026 0.0037 0.0039
Trichomonas vaginalis aldo/keto reductase, putative 0.0471 0.1878 0.4397
Brugia malayi RE15519p 0.0082 0.027 0.0268
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0161 0.0847
Leishmania major trypanothione reductase 0.0051 0.0141 0.0741
Schistosoma mansoni neuropeptide F-like receptor 0.0082 0.027 0.0268
Onchocerca volvulus 0.0512 0.2047 0.2042
Schistosoma mansoni blooms syndrome DNA helicase 0.0039 0.0089 0.0086
Plasmodium falciparum glyoxalase I 0.0374 0.1475 1
Echinococcus multilocularis aryl hydrocarbon receptor 0.0053 0.0147 0.0203
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0297 0.0295
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0471 0.1878 0.2114
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0161 0.0155
Schistosoma mansoni myosin xvIII 0.0082 0.027 0.0268
Toxoplasma gondii kringle domain-containing protein 0.0354 0.1393 0.7412
Brugia malayi chromobox protein homolog 3 0.0054 0.0153 0.0151
Mycobacterium ulcerans short chain dehydrogenase 0.0046 0.012 0.063
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0099 0.0109
Echinococcus granulosus slit 2 protein 0.0339 0.1332 0.1499
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0053 0.0147 0.0774
Echinococcus multilocularis neurogenic locus notch protein 0.0339 0.1332 0.1858
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0046 0.012 0.0118
Onchocerca volvulus 0.0339 0.1332 0.1327
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0297 0.0295
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0012 0.0011
Echinococcus multilocularis neuropeptide Y receptor 0.0082 0.027 0.0374
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0004
Echinococcus granulosus intermediate filament protein 0.0119 0.0423 0.0474
Brugia malayi Fibulin-1 precursor 0.0112 0.039 0.0389
Echinococcus multilocularis aldo keto reductase 0.0471 0.1878 0.2621
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0297 0.0411
Onchocerca volvulus Bile acid receptor homolog 0.0106 0.0366 0.036
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0069 0.0356
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0082 0.027 0.0301
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0082 0.027 0.0268
Echinococcus granulosus General substrate transporter 0.0032 0.0062 0.0067
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0047 0.0121 0.0637
Schistosoma mansoni hypothetical protein 0.0026 0.0037 0.0035
Brugia malayi neuropeptide F receptor 0.0082 0.027 0.0268
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0112 0.039 0.0384
Brugia malayi hypothetical protein 0.0118 0.0419 0.0417
Trichomonas vaginalis myo-inositol transporter, putative 0.0019 0.0006 0.001
Schistosoma mansoni intermediate filament proteins 0.0119 0.0423 0.0421
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0123 0.0282
Schistosoma mansoni ankyrin 23/unc44 0.0042 0.0101 0.0099
Echinococcus multilocularis neuroglian 0.0032 0.006 0.0081
Echinococcus granulosus g protein coupled receptor 0.0082 0.027 0.0301
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Loa Loa (eye worm) hypothetical protein 0.0106 0.0366 0.036
Schistosoma mansoni hypothetical protein 0.0339 0.1332 0.1331
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0019 0.0093
Schistosoma mansoni lipoxygenase 0.0246 0.0948 0.0946
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.0448 0.1908
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0129
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0033 0.0066 0.0342
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0099 0.0135
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0046 0.012 0.063
Echinococcus granulosus fatty acid binding protein FABP2 0.0036 0.0077 0.0085
Mycobacterium ulcerans hypothetical protein 0.0224 0.0855 0.4547
Onchocerca volvulus 0.0471 0.1878 0.1873
Schistosoma mansoni fatty acid binding protein 0.0036 0.0077 0.0075
Brugia malayi EGF-like domain containing protein 0.0339 0.1332 0.1331
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0017 0.0077
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0123 0.0653
Loa Loa (eye worm) hypothetical protein 0.0132 0.0475 0.0469
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0009 0.0048
Loa Loa (eye worm) hypothetical protein 0.0224 0.0855 0.0849
Schistosoma mansoni histamine h1 receptor 0.0082 0.027 0.0268
Schistosoma mansoni sugar transporter 0.0019 0.0006 0.0004
Schistosoma mansoni gliotactin 0.0033 0.0066 0.0064
Schistosoma mansoni neuropeptide receptor 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.1733 0.71 0.7099
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0069 0.4594
Trypanosoma brucei trypanothione reductase 0.0051 0.0141 0.0751
Loa Loa (eye worm) hypothetical protein 0.0339 0.1332 0.1327
Brugia malayi bHLH-PAS transcription factor 0.0151 0.0552 0.055
Brugia malayi conserved hypotetical protein 0.005 0.0135 0.0133
Brugia malayi SET domain containing protein 0.0029 0.0049 0.0047
Brugia malayi hypothetical protein 0.0082 0.027 0.0268
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0106 0.0563
Schistosoma mansoni amine GPCR 0.0082 0.027 0.0268
Echinococcus granulosus Immunoglobulin 0.0025 0.0033 0.0035
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0033 0.0066 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.027 0.0374
Loa Loa (eye worm) cytochrome P450 family protein 0.0152 0.0557 0.0551
Mycobacterium ulcerans hypothetical protein 0.0086 0.0286 0.1515
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0021 0.0017 0.0077
Loa Loa (eye worm) TK/EGFR protein kinase 0.0157 0.0577 0.0571
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0082 0.027 0.0268
Loa Loa (eye worm) hypothetical protein 0.0106 0.0366 0.036
Echinococcus multilocularis voltage gated potassium channel subunit 0.0256 0.0987 0.1376
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0123 0.0642
Trichomonas vaginalis aldo-keto reductase, putative 0.0471 0.1878 0.4397
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0047 0.0121 0.0637
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0161 0.0155
Toxoplasma gondii cytochrome p450 superfamily protein 0.0047 0.0121 0.0637
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.0448 0.0446
Brugia malayi nuclear receptor RXR 0.0056 0.016 0.0158
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0053 0.0147 0.0774
Schistosoma mansoni notch 0.0339 0.1332 0.1331
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Echinococcus granulosus Solute carrier organic anion transporter family 0.0029 0.0049 0.0053
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.005 0.0135 0.015
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0099 0.0135
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0106 0.0366 0.0509
Onchocerca volvulus 0.0029 0.0049 0.0042
Onchocerca volvulus 0.0082 0.027 0.0263
Toxoplasma gondii thioredoxin reductase 0.0051 0.0141 0.0741
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0085 0.0365
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0123 0.0282
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0047 0.0121 0.0637
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.027 0.0301
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0106 0.0366 0.0364
Echinococcus granulosus fatty acid binding protein FABP2 0.0036 0.0077 0.0085
Loa Loa (eye worm) hypothetical protein 0.0082 0.027 0.0263
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0256 0.0987 0.0985
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0006 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0017 0.0077
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0141 0.0157
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.001
Schistosoma mansoni hypothetical protein 0.0051 0.014 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0043 0.0097
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1045 0.2443
Echinococcus granulosus synaptic vesicle 2 protein 0.0019 0.0006 0.0005
Brugia malayi Intermediate filament tail domain containing protein 0.0119 0.0423 0.0421
Entamoeba histolytica recQ family helicase, putative 0.0026 0.0037 0.0089
Schistosoma mansoni cercarial elastase (S01 family) 0.0224 0.0855 0.0853
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0224 0.0855 0.1192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0073 0.0166
Loa Loa (eye worm) animal heme peroxidase 0.1733 0.71 0.7099
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0374 0.1475 0.7852
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0036 0.0077 0.0075
Echinococcus granulosus aldo keto reductase 0.0471 0.1878 0.2114
Entamoeba histolytica hypothetical protein 0.0133 0.0479 0.2043

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) > 30 % Inhibition of Flt3 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of InR at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of IGF1R at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of FGFR1 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of Flt4 at 10 uM ChEMBL. 17481893
Activity (binding) = 30 % Inhibition of ErbB1 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of ErbB2/Her2 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of cMet at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of PKA at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of GSK3beta at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of PKB/Akt at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of bcr-Abl at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of Cdk1 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of Raf1 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of Cdk2 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of Flt3 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of IGF1R at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of FGFR1 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of Flt4 at 10 uM ChEMBL. 17481893
Activity (binding) = 30 % Inhibition of ErbB1 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of ErbB2/Her2 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of cMet at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of GSK3beta at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of PKB/Akt at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of Raf1 at 10 uM ChEMBL. 17481893
Activity (binding) > 30 % Inhibition of Cdk2 at 10 uM ChEMBL. 17481893
IC50 (functional) > 10 uM Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA ChEMBL. 17481893
IC50 (functional) > 10 uM Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay ChEMBL. 17481893
IC50 (functional) > 10 uM Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay ChEMBL. 17481893
IC50 (functional) > 10 uM Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA ChEMBL. 17481893
IC50 (functional) > 10 uM Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay ChEMBL. 17481893
IC50 (functional) > 10 uM Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay ChEMBL. 17481893

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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