Detailed information for compound 44517

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 603.755 | Formula: C33H45N7O4
  • H donors: 6 H acceptors: 4 LogP: 3.96 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 3
  • SMILES: NC(=N)NCCC[C@@H](C(=O)N[C@H](C(=O)N)Cc1ccccc1)NC(=O)[C@@H](NC(=O)/C=C/c1ccccc1)CC1CCCCC1
  • InChi: 1S/C33H45N7O4/c34-30(42)27(21-24-13-6-2-7-14-24)40-31(43)26(17-10-20-37-33(35)36)39-32(44)28(22-25-15-8-3-9-16-25)38-29(41)19-18-23-11-4-1-5-12-23/h1-2,4-7,11-14,18-19,25-28H,3,8-10,15-17,20-22H2,(H2,34,42)(H,38,41)(H,39,44)(H,40,43)(H4,35,36,37)/b19-18+/t26-,27-,28-/m0/s1
  • InChiKey: RGCRSALIWMLCAP-URFKUNIZSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor II (thrombin) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Huntingtin homolog 0.0121 0.0259 0.0377
Schistosoma mansoni neuronal calcium sensor 0.0154 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0121 0.0259 0.0259
Leishmania major kinesin, putative 0.0679 0.2033 0.2965
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0039 0.0001 0.0003
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2197 0.6857 0.6857
Echinococcus granulosus neural cadherin 0.0043 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0055 0.005 0.005
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0236 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0182 0.0453 0.0453
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0273 0.0744 0.2063
Onchocerca volvulus 0.1083 0.3316 0.4835
Trypanosoma brucei proteasome alpha 7 subunit 0.0039 0.0001 0.0001
Toxoplasma gondii kringle domain-containing protein 0.0047 0.0026 0.0037
Brugia malayi Cadherin domain containing protein 0.0043 0.0012 0.0012
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0524 0.0524
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0012 0.0012
Toxoplasma gondii calcium-dependent protein kinase 0.0157 0.0373 0.0544
Onchocerca volvulus 0.1083 0.3316 0.4835
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0039 0.0001 0.0003
Toxoplasma gondii hypothetical protein 0.0283 0.0776 0.1132
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Plasmodium vivax vivapain-3 0.0601 0.1787 0.5388
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0039 0.0001 0.0003
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0039 0.0001 0.0003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0524 0.0524
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0012 0.0012
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.014 0.0321 0.0321
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.0343 0.0343
Schistosoma mansoni inhibitor of apoptosis protein 0.0182 0.0453 0.0453
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0318 0.0318
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0701 0.2105 0.3485
Brugia malayi Calcium binding EGF domain containing protein 0.0043 0.0012 0.0012
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0039 0.0001 0.0003
Trichomonas vaginalis glycogen phosphorylase, putative 0.0123 0.0266 0.0737
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3186 1 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0244 0.065 0.1802
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0328 0.0919 0.0919
Entamoeba histolytica cysteine protease, putative 0.0273 0.0744 0.2244
Onchocerca volvulus Prolyl endopeptidase homolog 0.2197 0.6857 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2718 0.8514 0.8514
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1083 0.3316 0.9194
Trichomonas vaginalis calcium binding protein, putative 0.0154 0.0365 0.1011
Echinococcus multilocularis beta LACTamase domain containing family member 0.011 0.0225 0.0225
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Loa Loa (eye worm) hypothetical protein 0.011 0.0225 0.0225
Brugia malayi hypothetical protein 0.0176 0.0435 0.0435
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0283 0.0776 0.1132
Echinococcus multilocularis tumor protein p63 0.0711 0.2135 0.2135
Onchocerca volvulus 0.0182 0.0453 0.0659
Loa Loa (eye worm) ctsf protein 0.1083 0.3316 0.3316
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.0225 0.0225
Toxoplasma gondii peptidase, T1 family protein 0.0039 0.0001 0.0001
Trypanosoma cruzi kinesin, putative 0.0679 0.2033 0.2033
Plasmodium vivax vivapain-2 0.1083 0.3316 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0962 0.2933 0.2933
Trypanosoma brucei cysteine peptidase C (CPC) 0.1174 0.3607 0.526
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.006 0.0068 0.0068
Brugia malayi Angiotensin-converting enzyme family protein 0.1227 0.3776 0.3776
Onchocerca volvulus 0.0204 0.0524 0.0762
Echinococcus granulosus cathepsin L cysteine proteinase 0.1083 0.3316 0.3316
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1174 0.3607 1
Echinococcus multilocularis calmodulin 0.0154 0.0365 0.0365
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0089 0.0158 0.0231
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0043 0.0012 0.0012
Echinococcus multilocularis apoptotic protease activating factor 1 0.0176 0.0435 0.0435
Echinococcus multilocularis gamma secretase subunit aph 1 0.0264 0.0715 0.0715
Trypanosoma brucei Calpain-like protein 2 0.0283 0.0776 0.1132
Entamoeba histolytica cysteine proteinase 1, putative 0.0601 0.1787 0.5388
Leishmania major calmodulin, putative 0.0154 0.0365 0.0532
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0601 0.1787 0.2606
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.0225 0.0225
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0012 0.0012
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0283 0.0776 0.1132
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1174 0.3607 0.3607
Loa Loa (eye worm) blistered cuticle protein 3 0.0411 0.1181 0.1181
Schistosoma mansoni caspase-3 (C14 family) 0.0131 0.0293 0.0293
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.0776
Schistosoma mansoni centrin-related 0.0154 0.0365 0.0365
Echinococcus granulosus slit 2 protein 0.0043 0.0012 0.0012
Giardia lamblia Alanyl dipeptidyl peptidase 0.0257 0.0692 0.192
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2197 0.6857 0.6857
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Trichomonas vaginalis calpain, putative 0.0283 0.0776 0.2152
Plasmodium vivax hypothetical protein, conserved 0.0257 0.0692 0.2088
Mycobacterium tuberculosis Long conserved protein 0.0211 0.0546 0.0904
Brugia malayi Papain family cysteine protease containing protein 0.0273 0.0744 0.0744
Entamoeba histolytica prolyl oligopeptidase family protein 0.0257 0.0692 0.2088
Mycobacterium tuberculosis Conserved hypothetical protein 0.0211 0.0546 0.0904
Leishmania major proteasome alpha 1 subunit, putative 0.0039 0.0001 0.0001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Leishmania major cathepsin L-like protease 0.1083 0.3316 0.4836
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0273 0.0744 0.2063
Brugia malayi notch-like transmembrane receptor 0.0043 0.0012 0.0012
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1174 0.3607 0.526
Brugia malayi A-kinase anchor protein 10, precursor 0.0043 0.0012 0.0012
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0039 0.0001 0.0003
Plasmodium vivax hypothetical protein, conserved 0.006 0.0068 0.0205
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0039 0.0001 0.0001
Trypanosoma cruzi centrin-3 0.0158 0.0376 0.0376
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Trichomonas vaginalis hypothetical protein 0.0283 0.0776 0.2152
Loa Loa (eye worm) hypothetical protein 0.3186 1 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0962 0.2933 0.2933
Loa Loa (eye worm) fli-1 protein 0.0225 0.0592 0.0592
Echinococcus granulosus beta LACTamase domain containing family member 0.011 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0328 0.0919 0.0919
Trypanosoma cruzi cysteine proteinase, putative 0.0601 0.1787 0.1787
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0012 0.0012
Brugia malayi calpain 5 0.0679 0.2033 0.2033
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.014 0.0321 0.0468
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0353 0.0998 0.0998
Echinococcus granulosus Mastin 0.0204 0.0524 0.0524
Echinococcus granulosus calmodulin 0.0154 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.1886 0.5868 0.5868
Trichomonas vaginalis calcineurin B subunit, putative 0.0157 0.0373 0.1035
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0273 0.0744 0.2063
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0039 0.0001 0.0003
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0602 0.1788 0.2606
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0012 0.0032
Entamoeba histolytica calcium-binding protein, putative 0.0154 0.0365 0.11
Toxoplasma gondii proteasome subunit beta type 1, putative 0.014 0.0321 0.0468
Entamoeba histolytica cysteine protease, putative 0.0273 0.0744 0.2244
Giardia lamblia Cysteine protease 0.0273 0.0744 0.2063
Mycobacterium tuberculosis Conserved protein 0.011 0.0225 0.0372
Brugia malayi Proteasome A-type and B-type family protein 0.0039 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Echinococcus granulosus peroxidasin 0.0411 0.1181 0.1181
Loa Loa (eye worm) hypothetical protein 0.0047 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trypanosoma brucei calpain-like protein, putative 0.0962 0.2933 0.4278
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0012 0.0012
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0257 0.0692 0.101
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0039 0.0001 0.0003
Echinococcus granulosus histone lysine methyltransferase setb 0.0102 0.0199 0.0199
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0602 0.1788 0.1788
Echinococcus multilocularis centrin 2 0.0154 0.0365 0.0365
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Echinococcus granulosus calpain 7 C02 family 0.0962 0.2933 0.2933
Plasmodium vivax proteasome subunit beta type-1, putative 0.014 0.0321 0.0968
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0089 0.0158 0.0438
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0273 0.0744 0.2063
Entamoeba histolytica cysteine proteinase, putative 0.0601 0.1787 0.5388
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0962 0.2933 0.2933
Echinococcus multilocularis proteasome subunit beta type 7 0.0039 0.0001 0.0001
Entamoeba histolytica glycogen phosphorylase, putative 0.0123 0.0266 0.0802
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.006 0.0068 0.0068
Brugia malayi Proteasome subunit alpha type 7-1 0.0039 0.0001 0.0001
Entamoeba histolytica glycogen phosphorylase, putative 0.0123 0.0266 0.0802
Schistosoma mansoni gamma-secretase subunit aph-1 0.0264 0.0715 0.0715
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0273 0.0744 0.0744
Giardia lamblia Cathepsin B precursor 0.0273 0.0744 0.2063
Echinococcus multilocularis Mastin 0.0204 0.0524 0.0524
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0039 0.0001 0.0003
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0273 0.0744 0.2063
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0244 0.065 0.2397
Trypanosoma brucei calmodulin, putative 0.0157 0.0373 0.0544
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0244 0.065 0.1802
Mycobacterium ulcerans lipase LipD 0.011 0.0225 0.083
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0962 0.2933 0.2933
Brugia malayi prolyl oligopeptidase family protein 0.0353 0.0998 0.0998
Brugia malayi proteasome subunit alpha type 6 0.0039 0.0001 0.0001
Plasmodium vivax vivapain-2 0.1083 0.3316 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0273 0.0744 0.0744
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0273 0.0744 0.2063
Mycobacterium tuberculosis Probable peptidase 0.0892 0.2709 0.4485
Trypanosoma cruzi calmodulin, putative 0.0154 0.0365 0.0365
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0154 0.0365 0.0365
Entamoeba histolytica cysteine protease, putative 0.0273 0.0744 0.2244
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0962 0.2933 0.4278
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1083 0.3316 0.9194
Echinococcus granulosus enteropeptidase 0.0204 0.0524 0.0524
Trichomonas vaginalis calmodulin, putative 0.0154 0.0365 0.1011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3186 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0365 0.1011
Trichomonas vaginalis calcineurin B subunit, putative 0.0154 0.0365 0.1011
Plasmodium falciparum serine repeat antigen 6 0.0273 0.0744 0.2244
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0157 0.0373 0.0373
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0154 0.0365 0.0365
Schistosoma mansoni ef hand domain family member A2 0.0154 0.0365 0.0365
Echinococcus granulosus neurogenic locus notch protein 0.0043 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0101 0.0197 0.0197
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0039 0.0001 1
Schistosoma mansoni notch 0.0043 0.0012 0.0012
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0012 0.0012
Loa Loa (eye worm) animal heme peroxidase 0.0411 0.1181 0.1181
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1083 0.3316 0.9194
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0283 0.0776 0.0776
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0102 0.0199 0.0199
Echinococcus granulosus EF HAND 1 calcium binding site 0.0154 0.0365 0.0365
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0039 0.0001 0.0003
Echinococcus granulosus neurocalcin 0.0154 0.0365 0.0365
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.014 0.0321 0.0321
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0273 0.0744 0.2244
Brugia malayi Trypsin family protein 0.0204 0.0524 0.0524
Mycobacterium leprae probable zinc metalloprotease 0.0101 0.0197 0.0723
Loa Loa (eye worm) hypothetical protein 0.0204 0.0524 0.0524
Mycobacterium ulcerans hypothetical protein 0.0211 0.0546 0.2016
Entamoeba histolytica calpain large subunit domain III containing protein 0.0679 0.2033 0.613
Plasmodium falciparum metacaspase-like protein 0.006 0.0068 0.0205
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0892 0.2709 0.2709
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0113 0.0113
Onchocerca volvulus Cathepsin L homolog 0.1083 0.3316 0.4835
Echinococcus granulosus proteasome subunit beta type 7 0.0039 0.0001 0.0001
Leishmania major proteasome alpha 2 subunit, putative 0.0039 0.0001 0.0001
Leishmania major calmodulin-like protein 0.0154 0.0365 0.0532
Loa Loa (eye worm) glycogen phosphorylase 0.0123 0.0266 0.0266
Echinococcus multilocularis cathepsin L 0.0273 0.0744 0.0744
Entamoeba histolytica hypothetical protein 0.0273 0.0744 0.2244
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0602 0.1788 0.1788
Echinococcus granulosus calpain A 0.0962 0.2933 0.2933
Loa Loa (eye worm) EF hand family protein 0.0154 0.0365 0.0365
Onchocerca volvulus 0.0204 0.0524 0.0762
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0343 0.0952
Trypanosoma brucei Calpain-like protein 1.2 0.0283 0.0776 0.1132
Echinococcus multilocularis protein jagged 1 0.0043 0.0012 0.0012
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0264 0.0715 0.0715
Brugia malayi calpain family protein 1 0.2564 0.8025 0.8025
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0257 0.0692 0.0692
Brugia malayi 20S proteasome alpha5 subunit 0.0039 0.0001 0.0001
Schistosoma mansoni caspase-7 (C14 family) 0.0236 0.0627 0.0627
Onchocerca volvulus 0.0104 0.0207 0.03
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0892 0.2709 0.2709
Echinococcus granulosus proteasome prosome macropain 0.0244 0.065 0.065
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Leishmania major proteasome beta-1 subunit, putative 0.0039 0.0001 0.0001
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0039 0.0001 0.0001
Leishmania major calmodulin, putative 0.0154 0.0365 0.0532
Brugia malayi Delta serrate ligand family protein 0.0043 0.0012 0.0012
Entamoeba histolytica prolyl oligopeptidase family protein 0.0257 0.0692 0.2088
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Echinococcus granulosus cathepsin l cysteine peptidase 0.1083 0.3316 0.3316
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0273 0.0744 0.2244
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0343 0.0952
Plasmodium falciparum serine repeat antigen 2 0.0273 0.0744 0.2244
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0039 0.0001 0.0001
Leishmania major centrin, putative 0.0154 0.0365 0.0532
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0273 0.0744 0.2244
Plasmodium falciparum calpain 0.0283 0.0776 0.2341
Onchocerca volvulus Dual oxidase homolog 0.0411 0.1181 0.1722
Entamoeba histolytica cysteine protease, putative 0.0273 0.0744 0.2244
Giardia lamblia Cathepsin L precursor 0.0273 0.0744 0.2063
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0182 0.0453 0.0453
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0147 0.0343 0.0343
Plasmodium vivax proteasome subunit beta type-5, putative 0.0244 0.065 0.196
Trypanosoma cruzi cruzipain precursor, putative 0.0328 0.0919 0.0919
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.0663 0.0663
Mycobacterium ulcerans proteasome PrcA 0.0039 0.0001 0.0004
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0039 0.0001 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0601 0.1787 0.5388
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Echinococcus multilocularis peroxidasin 0.0411 0.1181 0.1181
Loa Loa (eye worm) hypothetical protein 0.0204 0.0524 0.0524
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.006 0.0068 0.0189
Leishmania major calpain family cysteine protease-like protein 0.0283 0.0776 0.1132
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0273 0.0744 0.2244
Loa Loa (eye worm) beta-lactamase 0.011 0.0225 0.0225
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0089 0.0158 0.0477
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0148 0.0346 0.0346
Leishmania major proteasome beta 3 subunit, putative 0.0039 0.0001 0.0001
Trypanosoma brucei proteasome beta 6 subunit 0.014 0.0321 0.0468
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0225 0.0623
Entamoeba histolytica grainin 2 0.0158 0.0376 0.1135
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0012 0.0012
Toxoplasma gondii centrin 0.0154 0.0365 0.0532
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0039 0.0001 0.0001
Echinococcus multilocularis glycogen phosphorylase 0.0123 0.0266 0.0266
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0273 0.0744 0.0744
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0039 0.0001 0.0003
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0012 0.0012
Mycobacterium tuberculosis Hypothetical protein 0.0211 0.0546 0.0904
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0962 0.2933 0.4278
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0012 0.0012
Schistosoma mansoni neuronal calcium sensor 0.0154 0.0365 0.0365
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.014 0.0321 0.089
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0343 0.0952
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Plasmodium falciparum serine repeat antigen 8 0.0273 0.0744 0.2244
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0273 0.0744 0.2063
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0089 0.0158 0.0158
Brugia malayi cathepsin Z-like cysteine proteinase 0.0273 0.0744 0.0744
Onchocerca volvulus 0.0176 0.0435 0.0633
Echinococcus granulosus glycogen phosphorylase 0.0123 0.0266 0.0266
Schistosoma mansoni z-protein (S1r protein) 0.0043 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0283 0.0776 0.2152
Plasmodium vivax aspartyl protease, putative 0.0113 0.0235 0.071
Onchocerca volvulus 0.0043 0.0012 0.0017
Onchocerca volvulus 0.0154 0.0365 0.0531
Echinococcus multilocularis fat cadherin tumor suppressor 0.0043 0.0012 0.0012
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Brugia malayi cathepsin F-like cysteine proteinase 0.0328 0.0919 0.0919
Loa Loa (eye worm) notch protein 0.0043 0.0012 0.0012
Entamoeba histolytica calmodulin, putative 0.0154 0.0365 0.11
Brugia malayi Cathepsin L-like precursor 0.1083 0.3316 0.3316
Toxoplasma gondii cathepsin CPC2 0.0273 0.0744 0.1085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0601 0.1787 0.1787
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.0663 0.0663
Echinococcus granulosus microtubule associated protein 2 0.1555 0.4816 0.4816
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1083 0.3316 0.9194
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0154 0.0365 0.11
Trypanosoma brucei hypothetical protein 0.0283 0.0776 0.1132
Toxoplasma gondii centrin, putative 0.0154 0.0365 0.0532
Brugia malayi PXA domain containing protein 0.0043 0.0012 0.0012
Echinococcus multilocularis notch 0.0043 0.0012 0.0012
Trypanosoma cruzi centrin, putative 0.0158 0.0376 0.0376
Schistosoma mansoni hypothetical protein 0.0043 0.0012 0.0012
Giardia lamblia High cysteine protein 0.0043 0.0012 0.0034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0273 0.0744 0.0744
Trichomonas vaginalis calcium binding protein, putative 0.0154 0.0365 0.1011
Echinococcus multilocularis cathepsin L cysteine protease 0.1083 0.3316 0.3316
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0039 0.0001 0.0001
Trypanosoma brucei Metacaspase-4 0.006 0.0068 0.0099
Giardia lamblia Hypothetical protein 0.0157 0.0373 0.1035
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0039 0.0001 0.0001
Schistosoma mansoni cathepsin C 0.0273 0.0744 0.0744
Loa Loa (eye worm) fibroinase 0.1083 0.3316 0.3316
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0962 0.2933 0.4278
Echinococcus multilocularis protein jagged 2 0.0043 0.0012 0.0012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0962 0.2933 0.2933
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0039 0.0001 0.0001
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.011 0.0225 0.083
Onchocerca volvulus Cathepsin L homolog 0.0273 0.0744 0.1084
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0148 0.0346 0.0346
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0283 0.0776 0.2152
Giardia lamblia Cathepsin L precursor 0.0273 0.0744 0.2063
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0273 0.0744 0.2244
Mycobacterium leprae conserved hypothetical protein 0.011 0.0225 0.0826
Entamoeba histolytica cysteine proteinase, putative 0.0601 0.1787 0.5388
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0892 0.2709 1
Leishmania major cathepsin L-like protease 0.1083 0.3316 0.4836
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Plasmodium falciparum proteasome subunit beta type-4 0.0039 0.0001 0.0003
Onchocerca volvulus Chorion peroxidase homolog 0.0411 0.1181 0.1722
Onchocerca volvulus Slit protein homolog 0.0043 0.0012 0.0017
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0039 0.0001 0.0003
Brugia malayi cathepsin L-like precursor 0.0754 0.2273 0.2273
Brugia malayi Cadherin domain containing protein 0.0043 0.0012 0.0012
Loa Loa (eye worm) proteasome subunit beta type 1 0.014 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0283 0.0776 0.0776
Loa Loa (eye worm) PXA domain-containing protein 0.0043 0.0012 0.0012
Trichomonas vaginalis glycogen phosphorylase, putative 0.0123 0.0266 0.0737
Echinococcus multilocularis endothelin converting enzyme 1 0.0101 0.0197 0.0197
Mycobacterium tuberculosis Conserved protein 0.0211 0.0546 0.0904
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0113 0.0113
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0039 0.0001 0.0003
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Giardia lamblia Cathepsin L-like protease 0.0273 0.0744 0.2063
Onchocerca volvulus Cathepsin L homolog 0.1083 0.3316 0.4835
Trypanosoma brucei calpain, putative 0.0283 0.0776 0.1132
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0039 0.0001 0.0001
Trypanosoma cruzi metacaspase 5, putative 0.006 0.0068 0.0068
Echinococcus multilocularis neurogenic locus notch protein 0.0043 0.0012 0.0012
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0039 0.0001 0.0001
Giardia lamblia Cathepsin L precursor 0.0273 0.0744 0.2063
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0283 0.0776 0.0776
Echinococcus multilocularis EF hand domain containing family member A2 0.0154 0.0365 0.0365
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0343 0.0952
Trichomonas vaginalis calmodulin, putative 0.0154 0.0365 0.1011
Schistosoma mansoni hypothetical protein 0.0154 0.0365 0.0365
Brugia malayi proteasome subunit alpha type 2 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0076 0.0119 0.0119
Loa Loa (eye worm) calpain 0.0962 0.2933 0.2933
Loa Loa (eye worm) trypsin family protein 0.0204 0.0524 0.0524
Plasmodium vivax proteasome subunit beta type-4, putative 0.0039 0.0001 0.0003
Brugia malayi regulator of G-protein signaling egl-10 0.0043 0.0012 0.0012
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0039 0.0001 0.0003
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0343 0.0952
Schistosoma mansoni neuronal calcium sensor 0.0154 0.0365 0.0365
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1083 0.3316 1
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0244 0.065 0.065
Onchocerca volvulus 0.0043 0.0012 0.0017
Brugia malayi Cathepsin L-like precursor 0.1083 0.3316 0.3316
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0039 0.0001 0.0001
Onchocerca volvulus 0.0154 0.0365 0.0531
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0283 0.0776 0.0776
Brugia malayi beta-lactamase 0.011 0.0225 0.0225
Brugia malayi proteasome subunit beta type 2 0.0089 0.0158 0.0158
Mycobacterium ulcerans zinc metalloprotease 0.0101 0.0197 0.0726
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0318 0.1174
Schistosoma mansoni hypothetical protein 0.0043 0.0012 0.0012
Brugia malayi calpain D 0.0283 0.0776 0.0776
Echinococcus granulosus expressed protein 0.0831 0.2517 0.2517
Echinococcus multilocularis programmed cell death protein 0.0158 0.0376 0.0376
Plasmodium falciparum cysteine repeat modular protein 1 0.0047 0.0026 0.0077
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0012 0.0012
Echinococcus multilocularis hypothetical protein 0.0962 0.2933 0.2933
Schistosoma mansoni peroxidasin 0.0411 0.1181 0.1181
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0039 0.0001 0.0003
Brugia malayi regulator of G-protein signaling rgs-7 0.0043 0.0012 0.0012
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0043 0.0012 0.0012
Giardia lamblia Cathepsin B precursor 0.0273 0.0744 0.2063
Loa Loa (eye worm) hypothetical protein 0.0104 0.0207 0.0207
Brugia malayi Cathepsin L-like precursor 0.0328 0.0919 0.0919
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.011 0.0225 0.0225
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0051 0.0038 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0601 0.1787 0.2606
Entamoeba histolytica cysteine proteinase, putative 0.0754 0.2273 0.6856
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.006 0.0068 0.0189
Loa Loa (eye worm) hypothetical protein 0.0075 0.0113 0.0113
Trypanosoma brucei Aph-1 protein, putative 0.0103 0.0203 0.0296
Trypanosoma cruzi 20S proteasome subunit 0.0089 0.0158 0.0158
Echinococcus granulosus proteasome subunit beta t family 0.0039 0.0001 0.0001
Brugia malayi beta-lactamase family protein 0.011 0.0225 0.0225
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0157 0.0373 0.0373
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0039 0.0001 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Echinococcus granulosus caspase 2 0.0236 0.0627 0.0627
Toxoplasma gondii cathepsin CPL 0.1083 0.3316 0.4836
Echinococcus multilocularis expressed protein 0.0831 0.2517 0.2517
Loa Loa (eye worm) hypothetical protein 0.011 0.0225 0.0225
Brugia malayi Ets-domain containing protein 0.0074 0.0112 0.0112
Schistosoma mansoni gabp alpha 0.0074 0.0112 0.0112
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0199 0.0199
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0273 0.0744 0.0744
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Echinococcus granulosus prolyl endopeptidase 0.2197 0.6857 0.6857
Echinococcus multilocularis calpain 5 0.0962 0.2933 0.2933
Plasmodium vivax hypothetical protein, conserved 0.011 0.0225 0.0678
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0148 0.0346 0.0346
Brugia malayi proteasome subunit beta type 3 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0204 0.0524 0.0524
Loa Loa (eye worm) hypothetical protein 0.0075 0.0113 0.0113
Mycobacterium tuberculosis Probable lipase LipE 0.011 0.0225 0.0372
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0273 0.0744 0.0744
Trypanosoma cruzi Aph-1 protein, putative 0.0103 0.0203 0.0203
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0601 0.1787 0.1787
Echinococcus granulosus protein jagged 2 0.0043 0.0012 0.0012
Entamoeba histolytica cysteine protease, putative 0.1083 0.3316 1
Loa Loa (eye worm) prolyl oligopeptidase 0.0602 0.1788 0.1788
Trichomonas vaginalis calcium binding proteins, putative 0.0154 0.0365 0.1011
Onchocerca volvulus Neurogenic locus notch homolog 0.0043 0.0013 0.0018
Leishmania major protein kinase, putative 0.0154 0.0365 0.0532
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Brugia malayi Pre-SET motif family protein 0.0709 0.2129 0.2129
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0053 0.0044 0.0074
Trichomonas vaginalis esterase, putative 0.011 0.0225 0.0623
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0257 0.0692 0.192
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0257 0.0692 0.2088
Loa Loa (eye worm) hypothetical protein 0.0328 0.0919 0.0919
Onchocerca volvulus 0.011 0.0225 0.0326
Chlamydia trachomatis glycogen phosphorylase 0.0123 0.0266 0.5
Loa Loa (eye worm) proteasome subunit beta type 3 0.0039 0.0001 0.0001
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0101 0.0197 0.0326
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0273 0.0744 0.2244
Plasmodium vivax serine-repeat antigen (SERA) 0.0273 0.0744 0.2244
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0199 0.0199
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Schistosoma mansoni hypothetical protein 0.0043 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0204 0.0524 0.0524
Schistosoma mansoni cathepsin F (C01 family) 0.0754 0.2273 0.2273
Plasmodium vivax aspartyl protease, putative 0.0113 0.0235 0.071
Plasmodium falciparum serine repeat antigen 5 0.0273 0.0744 0.2244
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0892 0.2709 0.3951
Leishmania major cathepsin L-like protease 0.1083 0.3316 0.4836
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0154 0.0365 0.0365
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0012 0.0012
Toxoplasma gondii hypothetical protein 0.0257 0.0692 0.101
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0524 0.0524
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0039 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0962 0.2933 0.2933
Trypanosoma cruzi Aph-1 protein, putative 0.0103 0.0203 0.0203
Echinococcus multilocularis cysteine protease 0.1083 0.3316 0.3316
Echinococcus granulosus endothelin converting enzyme 1 0.0101 0.0197 0.0197
Echinococcus granulosus fibropellin Ia 0.0043 0.0012 0.0012
Brugia malayi Animal haem peroxidase family protein 0.0411 0.1181 0.1181
Loa Loa (eye worm) hypothetical protein 0.0063 0.0077 0.0077
Echinococcus granulosus acylamino acid releasing enzyme 0.0257 0.0692 0.0692
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0039 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.1187 0.3649 0.5322
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0012 0.0012
Brugia malayi hypothetical protein 0.0269 0.0732 0.0732
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0602 0.1788 0.1788
Giardia lamblia 20S proteasome alpha subunit 2 0.0039 0.0001 0.0003
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0601 0.1787 0.1787
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0039 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.2281 0.7125 0.7125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0273 0.0744 0.2063
Leishmania major calmodulin-like protein 0.0154 0.0365 0.0532
Mycobacterium tuberculosis Probable conserved lipoprotein 0.011 0.0225 0.0372
Echinococcus granulosus calpain 0.0962 0.2933 0.2933
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0204 0.0524 0.0524
Echinococcus granulosus caspase 8 0.006 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.011 0.0225 0.0225
Brugia malayi Fli-1 protein 0.0225 0.0592 0.0592
Loa Loa (eye worm) calpain family protein 1 0.1886 0.5868 0.5868
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0039 0.0001 0.0001
Mycobacterium ulcerans esterase/lipase LipP 0.011 0.0225 0.083
Schistosoma mansoni peroxidasin 0.0411 0.1181 0.1181
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0273 0.0744 0.2063
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0043 0.0012 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0273 0.0744 0.0744
Echinococcus multilocularis cathepsin b 0.3186 1 1
Toxoplasma gondii proteasome beta subunit 0.0039 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0283 0.0776 0.2152
Onchocerca volvulus 0.0043 0.0012 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.1083 0.3316 0.3316
Plasmodium falciparum metacaspase 1 0.006 0.0068 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Schistosoma mansoni hypothetical protein 0.0043 0.0012 0.0012
Schistosoma mansoni Mername-AA248 (C02 family) 0.0962 0.2933 0.2933
Trypanosoma cruzi cysteine peptidase, putative 0.1187 0.3649 0.3649
Schistosoma mansoni cathepsin F (C01 family) 0.1083 0.3316 0.3316
Echinococcus granulosus cathepsin l1 0.0754 0.2273 0.2273
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.0343 0.0343
Schistosoma mansoni glycogen phosphorylase 0.0123 0.0266 0.0266
Schistosoma mansoni hypothetical protein 0.0043 0.0012 0.0012
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0962 0.2933 0.4278
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0043 0.0012 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.0744 0.2063
Trypanosoma cruzi cruzipain precursor, putative 0.1187 0.3649 0.3649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0754 0.2273 0.6303
Echinococcus multilocularis neural cadherin 0.0043 0.0012 0.0012
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0039 0.0001 0.0001
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0039 0.0001 0.0001
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0039 0.0001 0.0001
Entamoeba histolytica proteasome subunit beta type 1, putative 0.014 0.0321 0.0968
Brugia malayi Protein kinase domain containing protein 0.0047 0.0026 0.0026
Giardia lamblia Cathepsin B precursor 0.1174 0.3607 1
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0353 0.0998 0.1456
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0601 0.1787 0.1787
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0182 0.0453 0.0453
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0039 0.0001 0.0001
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0039 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0273 0.0744 0.2063
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1083 0.3316 0.3316
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0039 0.0001 0.0001
Trypanosoma brucei centrin, putative 0.0154 0.0365 0.0532
Mycobacterium leprae Conserved hypothetical protein 0.0211 0.0546 0.2013
Schistosoma mansoni slit 0.0043 0.0012 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0012 0.0012
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.006 0.0068 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0273 0.0744 0.2063
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0154 0.0365 0.0532
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0112 0.0112
Leishmania major cathepsin L-like protease 0.1083 0.3316 0.4836
Brugia malayi cathepsin L-like cysteine proteinase 0.0273 0.0744 0.0744
Trypanosoma cruzi caltractin, putative 0.0154 0.0365 0.0365
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0962 0.2933 0.4278
Brugia malayi Calmodulin-like protein 0.0154 0.0365 0.0365
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0273 0.0744 0.0744
Echinococcus multilocularis calpain family protein 1, d 0.1886 0.5868 0.5868
Entamoeba histolytica hypothetical protein, conserved 0.0257 0.0692 0.2088
Brugia malayi Proteasome subunit alpha type 1 0.0039 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0273 0.0744 0.2244
Leishmania major proteasome beta 2 subunit, putative 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Echinococcus multilocularis beta adrenergic receptor kinase 0.0043 0.0012 0.0012
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0273 0.0744 0.0744
Giardia lamblia 20S proteasome alpha subunit 7 0.0039 0.0001 0.0003
Echinococcus granulosus proteasome subunit alpha type 2 0.0039 0.0001 0.0001
Giardia lamblia Cathepsin B precursor 0.0273 0.0744 0.2063
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0102 0.0199 0.029
Entamoeba histolytica cysteine proteinase 2 0.0601 0.1787 0.5388
Echinococcus multilocularis cysteine protease 0.1083 0.3316 0.3316
Trichomonas vaginalis calmodulin, putative 0.0154 0.0365 0.1011
Onchocerca volvulus 0.0411 0.1181 0.1722
Leishmania major hypothetical protein, conserved 0.0047 0.0026 0.0037
Toxoplasma gondii proteasome subunit alpha1, putative 0.0039 0.0001 0.0001
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0051 0.0038 0.0038
Onchocerca volvulus Peroxidase homolog 0.0411 0.1181 0.1722
Trypanosoma cruzi calmodulin, putative 0.0154 0.0365 0.0365
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2718 0.8514 0.8514
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1083 0.3316 0.9194
Loa Loa (eye worm) hypothetical protein 0.0754 0.2273 0.2273
Echinococcus multilocularis regulator of G protein signaling 0.0043 0.0012 0.0012
Leishmania major hypothetical protein, conserved 0.011 0.0225 0.0328
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2197 0.6857 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0273 0.0744 0.2244
Echinococcus granulosus caspase 3 0.0071 0.0101 0.0101
Toxoplasma gondii proteasome subunit 0.0039 0.0001 0.0001
Brugia malayi Papain family cysteine protease containing protein 0.1083 0.3316 0.3316
Schistosoma mansoni calmodulin 0.0154 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.2197 0.6857 0.6857
Plasmodium vivax hypothetical protein, conserved 0.0157 0.0373 0.1125
Giardia lamblia Cathepsin B precursor 0.1174 0.3607 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0148 0.0346 0.0346
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0039 0.0001 0.0001
Toxoplasma gondii troponin c, isotype gamma, putative 0.0154 0.0365 0.0532
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0012 0.0032
Brugia malayi Trypsin family protein 0.0204 0.0524 0.0524
Trichomonas vaginalis calmodulin, putative 0.0154 0.0365 0.1011
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0283 0.0776 0.2152
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0273 0.0744 0.2244
Entamoeba histolytica hypothetical protein, conserved 0.0157 0.0373 0.1125
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0 0.5
Mycobacterium leprae Conserved hypothetical protein 0.0211 0.0546 0.2013
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0039 0.0001 0.0001
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0039 0.0001 0.0001
Brugia malayi hypothetical protein 0.0204 0.0524 0.0524
Trichomonas vaginalis centrin, putative 0.0154 0.0365 0.1011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0039 0.0001 0.0003
Plasmodium vivax unspecified product 0.0601 0.1787 0.5388
Leishmania major proteasome beta 7 subunit, putative 0.0039 0.0001 0.0001
Brugia malayi EGF-like domain containing protein 0.0043 0.0012 0.0012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0273 0.0744 0.0744
Toxoplasma gondii aspartyl protease ASP3 0.0113 0.0235 0.0343
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0273 0.0744 0.2063
Mycobacterium ulcerans putative transglutaminase-like protein 0.0211 0.0546 0.2016
Loa Loa (eye worm) PAS-3 protein 0.0039 0.0001 0.0001
Brugia malayi EGF-like domain containing protein 0.0043 0.0012 0.0012
Brugia malayi EF hand family protein 0.0154 0.0365 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0365 0.1011
Echinococcus multilocularis Glycosyl transferase, family 35 0.0123 0.0266 0.0266
Trichomonas vaginalis calmodulin-2, putative 0.0154 0.0365 0.1011
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0039 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0962 0.2933 0.2933
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.011 0.0225 0.0225
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0039 0.0001 0.0001
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0039 0.0001 0.0003
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0101 0.0197 0.0197
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0273 0.0744 0.0744
Trypanosoma brucei centrin-3 0.0158 0.0376 0.0549
Toxoplasma gondii prolyl endopeptidase 0.2197 0.6857 1
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0039 0.0001 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0318 0.1174
Trichomonas vaginalis conserved hypothetical protein 0.0283 0.0776 0.2152
Loa Loa (eye worm) hypothetical protein 0.0102 0.0199 0.0199
Onchocerca volvulus 0.0043 0.0012 0.0017
Trypanosoma cruzi cysteine proteinase, putative 0.0601 0.1787 0.1787
Giardia lamblia 20S proteasome alpha subunit 3 0.0039 0.0001 0.0003
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0089 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0273 0.0744 0.0744
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0039 0.0001 0.0001
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0039 0.0001 0.0003
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0892 0.2709 1
Brugia malayi hypothetical protein 0.0121 0.0259 0.0259
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0043 0.0012 0.0012
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0154 0.0365 0.1011
Giardia lamblia Encystation-specific protease 0.0273 0.0744 0.2063
Brugia malayi Peptidase family M13 containing protein 0.0101 0.0197 0.0197
Echinococcus granulosus proteasome subunit beta type 6 0.0039 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0859 0.2606 0.2606
Trichomonas vaginalis calpain, putative 0.0283 0.0776 0.2152
Loa Loa (eye worm) calpain D 0.0283 0.0776 0.0776
Giardia lamblia Cathepsin B precursor 0.1174 0.3607 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0283 0.0776 0.0776
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0353 0.0998 0.1456
Echinococcus multilocularis microtubule associated protein 2 0.1555 0.4816 0.4816
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1083 0.3316 0.3316
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0039 0.0001 0.0003
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0892 0.2709 0.4485
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.0744 0.2063
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0225 0.0225
Trypanosoma cruzi cysteine peptidase, putative 0.0328 0.0919 0.0919
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0283 0.0776 0.1132
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0039 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.1083 0.3316 1
Echinococcus granulosus cathepsin L 0.0601 0.1787 0.1787
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0273 0.0744 0.2063
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0039 0.0001 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0225 0.0623
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0154 0.0365 0.11
Giardia lamblia Glycogen phosphorylase 0.0123 0.0266 0.0737
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0204 0.0524 0.0524
Trichomonas vaginalis calcium binding protein, putative 0.0158 0.0376 0.1044
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0283 0.0776 0.0776
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0244 0.065 0.065
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0068 0.0189
Brugia malayi Calcium binding EGF domain containing protein 0.0043 0.0012 0.0012
Brugia malayi Cathepsin L-like precursor 0.1083 0.3316 0.3316
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0154 0.0365 0.0365
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0039 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.0692 0.0692
Echinococcus granulosus calbindin 32 0.0157 0.0373 0.0373
Schistosoma mansoni cathepsin D (A01 family) 0.0127 0.0279 0.0279
Brugia malayi Cathepsin L-like cysteine proteinase 0.0754 0.2273 0.2273
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0283 0.0776 0.2152
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Trichomonas vaginalis calpain, putative 0.0283 0.0776 0.2152
Trypanosoma cruzi centrin, putative 0.0158 0.0376 0.0376
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0039 0.0001 0.0001
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0283 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Schistosoma mansoni calpain-2 (C02 family) 0.0283 0.0776 0.0776
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.006 0.0068 0.0099
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0039 0.0001 0.0001
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0524 0.0524
Echinococcus multilocularis neurocalcin 0.0154 0.0365 0.0365
Giardia lamblia 20S proteasome alpha subunit 5 0.0039 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.011 0.0225 0.0225
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0039 0.0001 0.0001
Echinococcus multilocularis caspase 3 0.0071 0.0101 0.0101
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.0076 0.0119 0.0119
Trypanosoma brucei calpain-like protein, putative 0.0962 0.2933 0.4278
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0039 0.0001 0.0001
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0039 0.0001 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.006 0.0068 0.0189
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2718 0.8514 0.8514
Leishmania major cysteine peptidase A (CPA) 0.1083 0.3316 0.4836
Trypanosoma brucei hypothetical protein, conserved 0.0154 0.0365 0.0532
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0012 0.0012
Trypanosoma brucei calmodulin, putative 0.0154 0.0365 0.0532
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1083 0.3316 0.9194
Toxoplasma gondii EFHC1, putative 0.0154 0.0365 0.0532
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Brugia malayi hypothetical protein 0.0096 0.0182 0.0182
Toxoplasma gondii ABC1 family protein 0.011 0.0225 0.0328
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0039 0.0001 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.0225 0.0623
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0068 0.0189
Entamoeba histolytica calcium binding family protein 0.0154 0.0365 0.11
Onchocerca volvulus 0.0047 0.0026 0.0036
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0039 0.0001 0.0001
Trichomonas vaginalis calmodulin, putative 0.0154 0.0365 0.1011
Onchocerca volvulus Glycogen phosphorylase homolog 0.0123 0.0266 0.0386
Giardia lamblia Hypothetical protein 0.0273 0.0744 0.2063
Trypanosoma brucei metacaspase MCA3 0.006 0.0068 0.0099
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0039 0.0001 0.0001
Plasmodium vivax unspecified product 0.0328 0.0919 0.277
Mycobacterium tuberculosis Probable lipase LipD 0.011 0.0225 0.0372
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0039 0.0001 0.0003
Entamoeba histolytica calmodulin, putative 0.0154 0.0365 0.11
Loa Loa (eye worm) hypothetical protein 0.0204 0.0524 0.0524
Toxoplasma gondii proteasome subunit alpha type, putative 0.0039 0.0001 0.0001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1083 0.3316 0.3316
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0244 0.065 0.0948
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2564 0.8025 0.8025
Onchocerca volvulus 0.0204 0.0524 0.0762
Schistosoma mansoni cathepsin s 0.0328 0.0919 0.0919
Leishmania major metacaspase, putative 0.006 0.0068 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0148 0.0346 0.0346
Brugia malayi proteasome subunit alpha type 4 0.0039 0.0001 0.0001
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0204 0.0524 0.0524
Giardia lamblia Cathepsin L precursor 0.0273 0.0744 0.2063
Loa Loa (eye worm) peptidase C13 family protein 0.0147 0.0343 0.0343
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0047 0.0026 0.0077
Onchocerca volvulus Cathepsin F homolog 0.1083 0.3316 0.4835
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0257 0.0692 0.101
Trypanosoma cruzi cysteine peptidase, putative 0.0601 0.1787 0.1787
Plasmodium falciparum serine repeat antigen 3 0.0273 0.0744 0.2244
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0012 0.0032
Loa Loa (eye worm) hypothetical protein 0.0204 0.0524 0.0524
Schistosoma mansoni calpain C (C02 family) 0.0962 0.2933 0.2933
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0098 0.0187 0.0187
Onchocerca volvulus Cell death protein 3 homolog 0.0236 0.0627 0.0913
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0273 0.0744 0.2063
Loa Loa (eye worm) animal heme peroxidase 0.0411 0.1181 0.1181
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3186 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0273 0.0744 0.2063
Trypanosoma brucei metacaspase 5, putative 0.006 0.0068 0.0099
Toxoplasma gondii cathepsin CPC1 0.0273 0.0744 0.1085
Echinococcus multilocularis caspase 2 0.0236 0.0627 0.0627
Schistosoma mansoni cathepsin D (A01 family) 0.0127 0.0279 0.0279
Leishmania major hypothetical protein, unknown function 0.0283 0.0776 0.1132
Trypanosoma cruzi metacaspase, putative 0.006 0.0068 0.0068
Echinococcus multilocularis transmembrane protease serine 3 0.0204 0.0524 0.0524
Mycobacterium tuberculosis Probable esterase LipL 0.011 0.0225 0.0372
Plasmodium vivax SET domain protein, putative 0.0102 0.0199 0.06
Loa Loa (eye worm) hypothetical protein 0.0204 0.0524 0.0524
Trypanosoma brucei kinesin, putative 0.0679 0.2033 0.2965
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0039 0.0001 0.0001
Echinococcus multilocularis protein jagged 1 0.0043 0.0012 0.0012
Echinococcus multilocularis acylamino acid releasing enzyme 0.0257 0.0692 0.0692
Loa Loa (eye worm) Notch2 0.0043 0.0012 0.0012
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0039 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0318 0.1174
Echinococcus multilocularis neurogenic locus protein delta 0.0043 0.0012 0.0012
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0051 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Toxoplasma gondii calmodulin CAM1 0.0157 0.0373 0.0544
Mycobacterium tuberculosis Conserved hypothetical protein 0.0211 0.0546 0.0904
Leishmania major proteasome alpha 7 subunit, putative 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.1602 0.4968 0.4968
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0892 0.2709 0.3951
Schistosoma mansoni hypothetical protein 0.0154 0.0365 0.0365
Echinococcus granulosus tumor protein p63 0.0711 0.2135 0.2135
Brugia malayi prolyl oligopeptidase family protein 0.0257 0.0692 0.0692
Loa Loa (eye worm) hypothetical protein 0.011 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0076 0.0119 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0012 0.0032
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0273 0.0744 0.2063
Echinococcus granulosus Proteasome subunit alpha type 7 0.0039 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0273 0.0744 0.2244
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Echinococcus granulosus EF hand domain containing family member A2 0.0154 0.0365 0.0365
Onchocerca volvulus 0.1083 0.3316 0.4835
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0039 0.0001 0.0003
Loa Loa (eye worm) programmed cell death protein 6 0.0157 0.0373 0.0373
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0353 0.0998 0.1456
Echinococcus granulosus cathepsin b 0.3186 1 1
Schistosoma mansoni hypothetical protein 0.0211 0.0546 0.0546
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0524 0.0524
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0396 0.1135 0.1135
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0283 0.0776 0.0776
Plasmodium falciparum cysteine proteinase falcipain 1 0.0601 0.1787 0.5388
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0039 0.0001 0.0003
Toxoplasma gondii heat shock protein hslv, putative 0.0039 0.0001 0.0001
Schistosoma mansoni neuronal calcium sensor 0.0154 0.0365 0.0365
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0101 0.0197 0.0197
Giardia lamblia Transglutaminase/protease, putative 0.0211 0.0546 0.1514
Onchocerca volvulus 0.011 0.0225 0.0326
Brugia malayi calpain 5 0.0283 0.0776 0.0776
Trypanosoma brucei caltractin, putative 0.0158 0.0376 0.0549
Plasmodium vivax vivapain-1 0.0601 0.1787 0.5388
Echinococcus granulosus inhibitor of apoptosis protein 0.0182 0.0453 0.0453
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0012 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.011 0.0225 0.0328
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0343 0.0952
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Plasmodium vivax serine-repeat antigen (SERA) 0.0273 0.0744 0.2244
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0244 0.065 0.196
Echinococcus granulosus calumenin 0.0157 0.0373 0.0373
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0131 0.0293 0.0293
Leishmania major phospholipase c-like protein 0.0154 0.0365 0.0532
Onchocerca volvulus 0.0273 0.0744 0.1084
Brugia malayi carbohydrate phosphorylase 0.0123 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Schistosoma mansoni notch 0.0043 0.0013 0.0013
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0039 0.0001 0.0003
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0353 0.0998 0.0998
Trichomonas vaginalis peptide N-glycanase, putative 0.0211 0.0546 0.1514
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0043 0.0012 0.0012
Echinococcus granulosus programmed cell death protein 0.0158 0.0376 0.0376
Trypanosoma brucei antigen, putative 0.0962 0.2933 0.4278
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0353 0.0998 0.1456
Trypanosoma brucei oligopeptidase b 0.0892 0.2709 0.3951
Plasmodium vivax calpain, putative 0.0962 0.2933 0.8846
Echinococcus granulosus Transglutaminase 0.0211 0.0546 0.0546
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0524 0.0524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Trichomonas vaginalis centrin, putative 0.0154 0.0365 0.1011
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Trypanosoma cruzi cysteine peptidase, putative 0.1187 0.3649 0.3649
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.0776
Onchocerca volvulus 0.1083 0.3316 0.4835
Entamoeba histolytica hypothetical protein 0.0043 0.0012 0.0035
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0012 0.0012
Echinococcus multilocularis cathepsin L cysteine protease 0.1083 0.3316 0.3316
Schistosoma mansoni calmodulin 0.0154 0.0365 0.0365
Brugia malayi prolyl oligopeptidase family protein 0.0602 0.1788 0.1788
Echinococcus granulosus cathepsin b 0.3186 1 1
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0068 0.0189
Entamoeba histolytica cysteine proteinase, putative 0.0601 0.1787 0.5388
Giardia lamblia Alanyl dipeptidyl peptidase 0.0257 0.0692 0.192
Plasmodium falciparum plasmepsin X 0.0113 0.0235 0.071
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0328 0.0919 0.0919
Loa Loa (eye worm) hypothetical protein 0.0076 0.0119 0.0119
Trypanosoma cruzi metacaspase, putative 0.006 0.0068 0.0068
Leishmania major centrin, putative 0.0154 0.0365 0.0532
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0039 0.0001 0.0001
Echinococcus granulosus apoptotic protease activating factor 1 0.0176 0.0435 0.0435
Onchocerca volvulus 0.0204 0.0524 0.0762
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0039 0.0001 0.0003
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0043 0.0012 0.0012
Echinococcus granulosus cathepsin L cysteine protease 0.0601 0.1787 0.1787
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0012 0.0012
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0039 0.0001 0.0001
Giardia lamblia Cathepsin B precursor 0.0273 0.0744 0.2063
Plasmodium falciparum plasmepsin IX 0.0113 0.0235 0.071
Entamoeba histolytica glycogen phosphorylase, putative 0.0053 0.0044 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Loa Loa (eye worm) calmodulin-like protein 0.0154 0.0365 0.0365
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1083 0.3316 0.9194
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.0225 0.0623
Brugia malayi Animal haem peroxidase family protein 0.0411 0.1181 0.1181
Brugia malayi hypothetical protein 0.0043 0.0012 0.0012
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0273 0.0744 0.0744
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0754 0.2273 0.6303
Echinococcus granulosus calpain 5 0.0962 0.2933 0.2933
Leishmania major calcineurin B subunit, putative 0.0154 0.0365 0.0532
Schistosoma mansoni notch 0.0043 0.0012 0.0012
Trichomonas vaginalis myosin light chain 1, putative 0.0154 0.0365 0.1011
Loa Loa (eye worm) hypothetical protein 0.2564 0.8025 0.8025
Brugia malayi Peroxidasin 0.0411 0.1181 0.1181
Echinococcus granulosus Glycosyl transferase family 35 0.0123 0.0266 0.0266
Schistosoma mansoni hypothetical protein 0.0176 0.0436 0.0436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Echinococcus multilocularis fibropellin Ia 0.0043 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.014 0.0321 0.0321
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0273 0.0744 0.2244
Trypanosoma brucei cysteine peptidase, putative 0.0283 0.0776 0.1132
Trypanosoma brucei mitochondrial calcium uptake 1 0.0154 0.0365 0.0532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0601 0.1787 0.4954
Giardia lamblia Cathepsin L precursor 0.0273 0.0744 0.2063
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0039 0.0001 0.0001
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0043 0.0012 0.0012
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0039 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0012 0.0032
Trypanosoma cruzi metacaspase, putative 0.006 0.0068 0.0068
Brugia malayi cathepsin Z-like cysteine proteinase 0.0273 0.0744 0.0744
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1227 0.3776 0.3776
Brugia malayi prolyl oligopeptidase family protein 0.2197 0.6857 0.6857
Schistosoma mansoni cathepsin F (C01 family) 0.1083 0.3316 0.3316
Brugia malayi EGF-like domain containing protein 0.0043 0.0012 0.0012
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0039 0.0001 0.0001
Echinococcus multilocularis proteasome subunit alpha type 2 0.0039 0.0001 0.0001
Schistosoma mansoni glycogen phosphorylase 0.0053 0.0044 0.0044
Loa Loa (eye worm) prolyl oligopeptidase 0.0257 0.0692 0.0692
Trypanosoma cruzi metacaspase, putative 0.006 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0075 0.0113 0.0113
Echinococcus granulosus transmembrane protease serine 3 0.0204 0.0524 0.0524
Echinococcus granulosus centrin 2 0.0154 0.0365 0.0365
Mycobacterium ulcerans beta-lactamase 0.011 0.0225 0.083
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0154 0.0365 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Loa Loa (eye worm) TK/ROR protein kinase 0.0047 0.0026 0.0026
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0039 0.0001 0.0003
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0039 0.0001 0.0001
Brugia malayi Blistered cuticle protein 3 0.0411 0.1181 0.1181
Plasmodium vivax proteasome subunit beta type-3, putative 0.0039 0.0001 0.0003
Echinococcus granulosus gamma secretase subunit aph 1 0.0264 0.0715 0.0715
Mycobacterium ulcerans hypothetical protein 0.0211 0.0546 0.2016
Leishmania major proteasome alpha 7 subunit, putative 0.0039 0.0001 0.0001
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0039 0.0001 0.0001
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0039 0.0001 0.0003
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0353 0.0998 0.0998
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0244 0.065 0.065
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Echinococcus multilocularis inhibitor of apoptosis protein 0.0182 0.0453 0.0453
Onchocerca volvulus Deterin homolog 0.0182 0.0453 0.0659
Echinococcus multilocularis calumenin 0.0157 0.0373 0.0373
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0089 0.0158 0.0438
Brugia malayi prolyl oligopeptidase family protein 0.0257 0.0692 0.0692
Trypanosoma brucei metacaspase 0.006 0.0068 0.0099
Loa Loa (eye worm) proteasome subunit beta type 2 0.0089 0.0158 0.0158
Brugia malayi hypothetical protein 0.017 0.0417 0.0417
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0039 0.0001 0.0001
Brugia malayi Calcium binding EGF domain containing protein 0.0043 0.0012 0.0012
Echinococcus multilocularis caspase 8 0.006 0.0068 0.0068
Schistosoma mansoni cell polarity protein 0.0043 0.0012 0.0012
Echinococcus granulosus glycoprotein Antigen 5 0.0204 0.0524 0.0524
Schistosoma mansoni ets-related 0.0225 0.0592 0.0592
Onchocerca volvulus Peroxidase homolog 0.0411 0.1181 0.1722
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0962 0.2933 0.2933
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0039 0.0001 0.0003
Mycobacterium tuberculosis Conserved protein 0.011 0.0225 0.0372
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0039 0.0001 0.0001
Echinococcus granulosus Regulator of G protein signaling 20 0.0043 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0012 0.0032
Schistosoma mansoni mitochondrial solute carrier 0.0154 0.0365 0.0365
Leishmania major oligopeptidase b 0.0892 0.2709 0.3951
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Brugia malayi hypothetical protein 0.0043 0.0012 0.0012
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0112 0.0112
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0273 0.0744 0.0744
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0039 0.0001 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0199 0.0199
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0039 0.0001 0.0001
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0039 0.0001 0.0001
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0039 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0068 0.0189
Giardia lamblia Cysteine protease 0.0273 0.0744 0.2063
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Brugia malayi Cell death protein 3 precursor 0.0236 0.0627 0.0627
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Toxoplasma gondii proteasome subunit beta type, putative 0.0244 0.065 0.0948
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0039 0.0001 0.0001
Brugia malayi EGF-like domain containing protein 0.0043 0.0012 0.0012
Loa Loa (eye worm) RGS-3 protein 0.0043 0.0012 0.0012
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0039 0.0001 0.0003
Trypanosoma cruzi calmodulin, putative 0.0154 0.0365 0.0365
Brugia malayi Papain family cysteine protease containing protein 0.0601 0.1787 0.1787
Brugia malayi Animal haem peroxidase family protein 0.0411 0.1181 0.1181
Brugia malayi Muscle positioning protein 4 0.0043 0.0012 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0244 0.065 0.065
Schistosoma mansoni hypothetical protein 0.0283 0.0776 0.0776
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0225 0.0225
Echinococcus multilocularis glycoprotein Antigen 5 0.0204 0.0524 0.0524
Onchocerca volvulus 0.005 0.0035 0.0049
Echinococcus multilocularis Regulator of G protein signaling 20 0.0043 0.0012 0.0012
Trypanosoma brucei I/6 autoantigen 0.0154 0.0365 0.0532
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0283 0.0776 0.2152
Leishmania major hypothetical protein, conserved 0.0157 0.0373 0.0544
Brugia malayi calcium-binding protein 0.0154 0.0365 0.0365
Trichomonas vaginalis set domain proteins, putative 0.0807 0.244 0.6765
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.006 0.0068 0.0099
Echinococcus granulosus cysteine protease 0.0601 0.1787 0.1787
Mycobacterium leprae Probable lipase LipE 0.011 0.0225 0.0826
Brugia malayi EGF-like domain containing protein 0.0043 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Schistosoma mansoni hypothetical protein 0.0176 0.0436 0.0436
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0148 0.0346 0.0346
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0112 0.0112
Entamoeba histolytica prolyl oligopeptidase family protein 0.0257 0.0692 0.2088
Schistosoma mansoni centrin 0.0154 0.0365 0.0365
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Entamoeba histolytica calpain family cysteine protease, putative 0.0283 0.0776 0.2341
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0207 0.0207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Toxoplasma gondii peptidase family M13 protein 0.0101 0.0197 0.0287
Trypanosoma cruzi I/6 autoantigen, putative 0.0154 0.0365 0.0365
Echinococcus multilocularis cathepsin L 0.0601 0.1787 0.1787
Entamoeba histolytica cysteine protease, putative 0.0273 0.0744 0.2244
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0139 0.0318 0.0318
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0273 0.0744 0.2244
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.006 0.0068 0.0189
Schistosoma mansoni hypothetical protein 0.0204 0.0524 0.0524
Plasmodium falciparum serine repeat antigen 1 0.0273 0.0744 0.2244
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0068 0.0189
Echinococcus granulosus Dipeptidyl peptidase 9 0.0353 0.0998 0.0998
Loa Loa (eye worm) hypothetical protein 0.0328 0.0919 0.0919
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0039 0.0001 0.0003
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0257 0.0692 0.2088
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0244 0.065 0.1076
Mycobacterium ulcerans transglutaminase family protein 0.0211 0.0546 0.2016
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0012 0.0012
Toxoplasma gondii EF hand domain-containing protein 0.0154 0.0365 0.0532
Schistosoma mansoni septate junction protein 0.0043 0.0012 0.0012
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.194 0.604 1
Brugia malayi Ets-domain containing protein 0.0074 0.0112 0.0112
Schistosoma mansoni reticulocalbin 0.0157 0.0373 0.0373
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0039 0.0001 0.0001
Leishmania major proteasome alpha 3 subunit, putative 0.0039 0.0001 0.0001
Echinococcus multilocularis programmed cell death protein 0.0158 0.0376 0.0376
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.0776
Brugia malayi Proteasome A-type and B-type family protein 0.0039 0.0001 0.0001
Onchocerca volvulus 0.1083 0.3316 0.4835
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.0273 0.0744 0.0744
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.0692 0.0692
Brugia malayi Proteasome A-type and B-type family protein 0.0244 0.065 0.065
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0089 0.0158 0.0231
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0043 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0257 0.0692 0.0692
Onchocerca volvulus 0.0204 0.0524 0.0762
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1174 0.3607 0.3607
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0039 0.0001 0.0002
Echinococcus granulosus calpain A 0.2721 0.8522 0.8522
Echinococcus multilocularis caspase 0.0131 0.0293 0.0293
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.006 0.0068 0.0189
Loa Loa (eye worm) hypothetical protein 0.0154 0.0365 0.0365
Echinococcus multilocularis Transglutaminase 0.0211 0.0546 0.0546
Echinococcus granulosus calcium uptake protein 1 0.0157 0.0373 0.0373
Trypanosoma brucei prolyl endopeptidase 0.2197 0.6857 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0378 0.1077 0.1077
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.011 0.0225 0.0372
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0039 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0043 0.0012 0.0035
Onchocerca volvulus 0.0754 0.2273 0.3314
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0273 0.0744 0.0744
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0039 0.0001 0.0001
Onchocerca volvulus 0.0411 0.1181 0.1722
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0039 0.0001 0.0001
Onchocerca volvulus 0.017 0.0417 0.0606
Plasmodium vivax proteasome subunit beta type-7, putative 0.0039 0.0001 0.0003
Entamoeba histolytica protein kinase, putative 0.0679 0.2033 0.613
Schistosoma mansoni calpain (C02 family) 0.0962 0.2933 0.2933
Loa Loa (eye worm) hypothetical protein 0.006 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.005 0.0035 0.0035
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0396 0.1135 0.1135
Giardia lamblia 20S proteasome alpha subunit 6 0.0039 0.0001 0.0003
Onchocerca volvulus 0.0157 0.0373 0.0543
Echinococcus multilocularis calpain 0.0962 0.2933 0.2933
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0273 0.0744 0.0744
Plasmodium falciparum proteasome subunit beta type-1, putative 0.014 0.0321 0.0968
Schistosoma mansoni hypothetical protein 0.0043 0.0012 0.0012
Brugia malayi Cytochrome P450 family protein 0.0058 0.0061 0.0061
Echinococcus granulosus survival motor neuron protein 1 0.0269 0.0732 0.0732
Loa Loa (eye worm) hypothetical protein 0.0273 0.0744 0.0744
Plasmodium falciparum serine repeat antigen 9 0.0273 0.0744 0.2244
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0039 0.0001 0.0003
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0283 0.0776 0.0776
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0139 0.0318 0.0527
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0039 0.0001 0.0001
Echinococcus granulosus glycogen phosphorylase 0.0123 0.0266 0.0266
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0039 0.0001 0.0003
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.006 0.0068 0.0099
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0039 0.0001 0.0003
Brugia malayi proteasome subunit alpha type 1 0.0039 0.0001 0.0001
Plasmodium vivax unspecified product 0.0273 0.0744 0.2244
Echinococcus multilocularis slit 2 protein 0.0043 0.0012 0.0012
Onchocerca volvulus 0.1083 0.3316 0.4835
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0053 0.0044 0.0164
Trypanosoma cruzi oligopeptidase b 0.0892 0.2709 0.2709
Entamoeba histolytica glycogen phosphorylase, putative 0.0053 0.0044 0.0134
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0039 0.0001 0.0001
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0154 0.0365 0.0365
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0273 0.0744 0.2244
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0154 0.0365 0.0365
Brugia malayi Kringle domain containing protein 0.0047 0.0026 0.0026
Schistosoma mansoni caspase-7 (C14 family) 0.0131 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.1083 0.3316 0.3316
Echinococcus multilocularis EF hand domain containing family member A2 0.0157 0.0373 0.0373
Brugia malayi GCC2 and GCC3 family protein 0.0043 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0257 0.0692 0.192
Loa Loa (eye worm) hypothetical protein 0.0101 0.0197 0.0197
Brugia malayi Animal haem peroxidase family protein 0.0411 0.1181 0.1181
Echinococcus multilocularis neurogenic locus notch protein 0.0043 0.0012 0.0012
Brugia malayi hypothetical protein 0.0411 0.1181 0.1181
Brugia malayi EGF-like domain containing protein 0.0043 0.0012 0.0012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0962 0.2933 0.2933
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0154 0.0365 0.0365
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0039 0.0001 0.0001
Toxoplasma gondii preprocathepsin c precursor, putative 0.0273 0.0744 0.1085
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0039 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0012 0.0012
Brugia malayi EGF-like domain containing protein 0.0043 0.0012 0.0012
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0039 0.0001 0.0001
Mycobacterium ulcerans proteasome PrcB 0.0244 0.065 0.2399
Brugia malayi Trypsin family protein 0.0204 0.0524 0.0524
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0012 0.0012
Giardia lamblia Hypothetical protein 0.0211 0.0546 0.1514
Plasmodium falciparum proteasome subunit beta type-5 0.0244 0.065 0.196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Schistosoma mansoni hypothetical protein 0.0182 0.0453 0.0453
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0273 0.0744 0.2244
Schistosoma mansoni calmodulin related calcium binding protein 0.0154 0.0365 0.0365
Echinococcus granulosus proteasome prosome macropain subunit beta 0.014 0.0321 0.0321
Toxoplasma gondii cathepsin B 0.1174 0.3607 0.526
Schistosoma mansoni cathepsin B (C01 family) 0.0273 0.0744 0.0744
Echinococcus granulosus tissue type plasminogen activator 0.0047 0.0026 0.0026
Giardia lamblia Proteasome subunit beta type 2 0.0089 0.0158 0.0438
Schistosoma mansoni microtubule-associated protein tau 0.1555 0.4816 0.4816
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1083 0.3316 0.9194
Brugia malayi proteasome subunit beta type 1 0.014 0.0321 0.0321
Giardia lamblia Cathepsin L-like protease 0.0273 0.0744 0.2063
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0273 0.0744 0.2063
Echinococcus granulosus subfamily T1A non peptidase ue 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0101 0.0197 0.0197
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0273 0.0744 0.0744
Echinococcus multilocularis proteasome (prosome, macropain) 0.0244 0.065 0.065
Schistosoma mansoni rab 0.0154 0.0365 0.0365
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0039 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0283 0.0776 0.1132
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.017 0.0417 0.0417
Brugia malayi calpain 7 0.0962 0.2933 0.2933
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0225 0.0623
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0012 0.0012
Onchocerca volvulus 0.011 0.0225 0.0326
Schistosoma mansoni hypothetical protein 0.0113 0.0235 0.0235
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0182 0.0453 0.0453
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0039 0.0001 0.0001
Plasmodium falciparum cysteine proteinase falcipain 3 0.1083 0.3316 1
Schistosoma mansoni hypothetical protein 0.0176 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Schistosoma mansoni laminin gamma-3 chain 0.0043 0.0012 0.0012
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0039 0.0001 0.0001
Onchocerca volvulus 0.1602 0.4968 0.7244
Brugia malayi gamma-secretase subunit aph-1 0.0264 0.0715 0.0715
Mycobacterium ulcerans hypothetical protein 0.011 0.0225 0.083
Echinococcus multilocularis calbindin 32 0.0157 0.0373 0.0373
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0012 0.0012
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0039 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0068 0.0189
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0039 0.0001 0.0001
Trypanosoma cruzi cysteine protease, putative 0.0601 0.1787 0.1787
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Leishmania major cathepsin L-like protease 0.1083 0.3316 0.4836
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0039 0.0001 0.0003
Loa Loa (eye worm) animal heme peroxidase 0.0411 0.1181 0.1181
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1083 0.3316 0.9194
Loa Loa (eye worm) hypothetical protein 0.0257 0.0692 0.0692
Plasmodium falciparum serine repeat antigen 7 0.0273 0.0744 0.2244
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0039 0.0001 0.0003
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0039 0.0001 0.0003
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0204 0.0524 0.0524
Loa Loa (eye worm) hypothetical protein 0.0754 0.2273 0.2273
Brugia malayi beta-lactamase family protein 0.011 0.0225 0.0225
Echinococcus granulosus cathepsin l1 0.1083 0.3316 0.3316
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Brugia malayi MH2 domain containing protein 0.0248 0.0663 0.0663
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0353 0.0998 0.0998
Echinococcus multilocularis tissue type plasminogen activator 0.0047 0.0026 0.0026
Schistosoma mansoni cathepsin S (C01 family) 0.0273 0.0744 0.0744
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0131 0.0293 0.0293
Schistosoma mansoni hypothetical protein 0.0043 0.0012 0.0012
Onchocerca volvulus 0.1083 0.3316 0.4835
Echinococcus granulosus EF hand domain containing family member A2 0.0157 0.0373 0.0373
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0039 0.0001 0.0001
Echinococcus granulosus Proteasome subunit alpha beta 0.0039 0.0001 0.0001
Brugia malayi calpain family protein 1 0.2564 0.8025 0.8025
Onchocerca volvulus Huntingtin homolog 0.0121 0.0259 0.0377
Echinococcus multilocularis proteasome subunit beta type 6 0.0039 0.0001 0.0001
Trypanosoma cruzi I/6 autoantigen, putative 0.0154 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Loa Loa (eye worm) calpain 5 0.0679 0.2033 0.2033
Loa Loa (eye worm) cathepsin B 0.1174 0.3607 0.3607
Brugia malayi EF hand family protein 0.0157 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Echinococcus multilocularis survival motor neuron protein 1 0.0269 0.0732 0.0732
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0039 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.1083 0.3316 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.005 0.005
Onchocerca volvulus 0.0043 0.0012 0.0017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0148 0.0346 0.0346
Echinococcus multilocularis calmodulin 0.0154 0.0365 0.0365
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0154 0.0365 0.0365
Giardia lamblia Cysteine protease 0.0273 0.0744 0.2063
Echinococcus multilocularis cathepsin b 0.3186 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0601 0.1787 0.1787
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Loa Loa (eye worm) hypothetical protein 0.0273 0.0744 0.0744
Trichomonas vaginalis calmodulin, putative 0.0157 0.0373 0.1035
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.006 0.0068 0.0189
Brugia malayi Thioredoxin family protein 0.0211 0.0546 0.0546
Leishmania major proteasome alpha 1 subunit, putative 0.0039 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.1187 0.3649 0.5322
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0039 0.0001 0.0001
Schistosoma mansoni calpain-7 (C02 family) 0.0965 0.2943 0.2943
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0273 0.0744 0.2063
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0273 0.0744 0.2063
Entamoeba histolytica grainin, putative 0.0157 0.0373 0.1125
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0039 0.0001 0.0003
Brugia malayi cathepsin F-like cysteine proteinase 0.0273 0.0744 0.0744
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Giardia lamblia Cathepsin L precursor 0.0273 0.0744 0.2063
Onchocerca volvulus 0.0055 0.005 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Loa Loa (eye worm) hypothetical protein 0.0075 0.0113 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0273 0.0744 0.2063
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0154 0.0365 0.0532
Loa Loa (eye worm) hypothetical protein 0.0154 0.0365 0.0365
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0039 0.0001 0.0001
Leishmania major programmed cell death 6 protein-like protein 0.0154 0.0365 0.0532
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2718 0.8514 0.8514
Loa Loa (eye worm) cysteine protease 0.1083 0.3316 0.3316
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trypanosoma cruzi kinesin, putative 0.0679 0.2033 0.2033
Leishmania major proteasome beta 2 subunit, putative 0.0089 0.0158 0.0231
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0043 0.0012 0.0012
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0039 0.0001 0.0003
Leishmania major hypothetical protein, conserved 0.0154 0.0365 0.0532
Echinococcus multilocularis enteropeptidase 0.0204 0.0524 0.0524
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.0776
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0273 0.0744 0.2244
Trypanosoma brucei metacaspase MCA2 0.006 0.0068 0.0099
Loa Loa (eye worm) hypothetical protein 0.0176 0.0435 0.0435
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0148 0.0346 0.0346
Trichomonas vaginalis calmodulin, putative 0.0158 0.0376 0.1044
Trichomonas vaginalis calmodulin, putative 0.0154 0.0365 0.1011
Echinococcus granulosus protein jagged 1 0.0043 0.0012 0.0012
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1083 0.3316 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.006 0.0068 0.0189
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Onchocerca volvulus Putative cubilin 0.0043 0.0012 0.0017
Schistosoma mansoni reticulocalbin 0.0154 0.0365 0.0365
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0039 0.0001 0.0001
Echinococcus multilocularis calpain A 0.2721 0.8522 0.8522
Brugia malayi Cathepsin L-like precursor 0.1083 0.3316 0.3316
Loa Loa (eye worm) hypothetical protein 0.0754 0.2273 0.2273
Brugia malayi Trypsin family protein 0.0204 0.0524 0.0524
Schistosoma mansoni glycogen phosphorylase 0.0123 0.0266 0.0266
Brugia malayi programmed cell death protein 6 0.0154 0.0365 0.0365
Brugia malayi Cathepsin L-like precursor 0.1083 0.3316 0.3316
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0318 0.0318
Brugia malayi fibroinase precursor 0.0273 0.0744 0.0744
Brugia malayi PXA domain containing protein 0.0043 0.0012 0.0012
Plasmodium vivax metacaspase 1, putative 0.006 0.0068 0.0205
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0962 0.2933 0.2933
Leishmania major i/6 autoantigen-like protein 0.0154 0.0365 0.0532
Onchocerca volvulus 0.0411 0.1181 0.1722
Trypanosoma cruzi cysteine peptidase, putative 0.1187 0.3649 0.3649
Trypanosoma brucei calpain-like protein, putative 0.0962 0.2933 0.4278
Brugia malayi Cathepsin L-like precursor 0.1083 0.3316 0.3316
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0204 0.0524 0.0524
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0039 0.0001 0.0001
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0039 0.0001 0.0001
Trichomonas vaginalis calcium binding protein, putative 0.0154 0.0365 0.1011
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0396 0.1135 0.1135
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Onchocerca volvulus Peroxidasin homolog 0.0411 0.1181 0.1722
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trypanosoma brucei calpain, putative 0.0283 0.0776 0.1132
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0012 0.0012
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0154 0.0365 0.1011
Echinococcus multilocularis geminin 0.0176 0.0436 0.0436
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0182 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0269 0.0732 0.0732
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0257 0.0692 0.192
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3186 1 1
Entamoeba histolytica glycogenphosphorylase, putative 0.0053 0.0044 0.0134
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0039 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0601 0.1787 0.4954
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0204 0.0524 0.0524
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.171 0.5309 0.5309
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1083 0.3316 0.9194
Echinococcus multilocularis calpain 7 (C02 family) 0.0962 0.2933 0.2933
Loa Loa (eye worm) calpain family protein 1 0.2564 0.8025 0.8025
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0273 0.0744 0.2244
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0051 0.0038 0.0038
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.0343 0.0952
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0012 0.0012
Schistosoma mansoni notch 0.0043 0.0012 0.0012
Plasmodium vivax proteasome subunit beta type-6, putative 0.0039 0.0001 0.0003
Echinococcus granulosus delta-like protein 1 0.0043 0.0012 0.0012
Onchocerca volvulus 0.0204 0.0524 0.0762
Brugia malayi Cathepsin L-like precursor 0.0754 0.2273 0.2273
Mycobacterium tuberculosis Probable hydrolase 0.011 0.0225 0.0372
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trypanosoma cruzi major cysteine proteinase, putative 0.0273 0.0744 0.0744
Toxoplasma gondii EGF family domain-containing protein 0.0043 0.0012 0.0018
Loa Loa (eye worm) hypothetical protein 0.0182 0.0453 0.0453
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0026 0.0026
Echinococcus multilocularis neurogenic locus protein delta 0.0043 0.0012 0.0012
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0039 0.0001 0.0003
Echinococcus granulosus caspase 0.0131 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Leishmania major cathepsin L-like protease 0.1187 0.3649 0.5322
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0148 0.0346 0.0346
Giardia lamblia 20S proteasome alpha subunit 4 0.0039 0.0001 0.0003
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0182 0.0453 0.0453
Brugia malayi Pre-SET motif family protein 0.0102 0.0199 0.0199
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1083 0.3316 0.9194
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0061 0.0061
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0709 0.2129 0.2129
Trypanosoma cruzi oligopeptidase b 0.0892 0.2709 0.2709
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0039 0.0001 0.0001
Trypanosoma cruzi conserved protein 0.0283 0.0776 0.0776
Trypanosoma brucei Calpain-like protein 1.1 0.0283 0.0776 0.1132
Echinococcus multilocularis proteasome subunit alpha type 6 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0096 0.0182 0.0182
Giardia lamblia Cysteine protease 0.0273 0.0744 0.2063
Echinococcus granulosus neurogenic locus protein delta 0.0043 0.0012 0.0012
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0089 0.0158 0.0477
Brugia malayi Peptidase C13 family protein 0.0147 0.0343 0.0343
Onchocerca volvulus 0.0807 0.2441 0.3559
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1083 0.3316 0.3316
Echinococcus granulosus notch 0.0043 0.0012 0.0012
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0154 0.0365 0.11
Mycobacterium tuberculosis Conserved protein 0.011 0.0225 0.0372
Schistosoma mansoni survival motor neuron protein 0.0055 0.005 0.005
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0283 0.0776 0.0776
Echinococcus granulosus geminin 0.0176 0.0436 0.0436
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.014 0.0321 0.0321
Brugia malayi Cathepsin L-like precursor 0.0754 0.2273 0.2273
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0139 0.0318 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Echinococcus multilocularis prolyl endopeptidase 0.2197 0.6857 0.6857
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0283 0.0776 0.0776
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0089 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0121 0.0259 0.0259
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0139 0.0318 0.0464
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Onchocerca volvulus Legumain homolog 0.0147 0.0343 0.0499
Toxoplasma gondii aldehyde dehydrogenase 0.0139 0.0318 0.0464
Onchocerca volvulus 0.0211 0.0546 0.0795
Giardia lamblia Proteasome subunit beta type 1 0.014 0.0321 0.089
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0039 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0076 0.0119 0.0119
Echinococcus granulosus neurogenic locus notch protein 0.0043 0.0012 0.0012
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0039 0.0001 0.0003
Echinococcus granulosus proteasome subunit alpha type 6 0.0039 0.0001 0.0001
Brugia malayi proteasome subunit alpha type 3 0.0039 0.0001 0.0001
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0039 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0204 0.0524 0.1933
Plasmodium vivax proteasome subunit beta type-2, putative 0.0089 0.0158 0.0477
Plasmodium vivax centrin-1, putative 0.0154 0.0365 0.11
Loa Loa (eye worm) hypothetical protein 0.0411 0.1181 0.1181
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0524 0.0524
Giardia lamblia 20S proteasome alpha subunit 1 0.0039 0.0001 0.0003
Plasmodium falciparum peptidase, putative 0.0257 0.0692 0.2088
Trichomonas vaginalis calmodulin, putative 0.0154 0.0365 0.1011
Loa Loa (eye worm) animal heme peroxidase 0.0411 0.1181 0.1181
Echinococcus granulosus cathepsin L 0.0273 0.0744 0.0744
Schistosoma mansoni memapsin-2 (A01 family) 0.0509 0.1492 0.1492
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3186 1 1
Giardia lamblia Proteasome subunit beta type 3 0.0039 0.0001 0.0003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0204 0.0524 0.0524
Leishmania major calpain protease-like protein 0.0283 0.0776 0.1132
Trypanosoma brucei protein I/6 0.0154 0.0365 0.0532
Leishmania major centrin, putative,caltractin, putative 0.0154 0.0365 0.0532
Echinococcus granulosus protein jagged 1 0.0043 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0076 0.0119 0.0119
Brugia malayi Trypsin-like protease protein 5 0.0204 0.0524 0.0524
Echinococcus granulosus neurogenic locus notch protein 4 0.0043 0.0012 0.0012
Brugia malayi Proteasome A-type and B-type family protein 0.0039 0.0001 0.0001
Echinococcus granulosus protein jagged 2 0.0043 0.0012 0.0012
Onchocerca volvulus Peroxidasin homolog 0.0411 0.1181 0.1722
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0273 0.0744 0.2063
Echinococcus granulosus beta-adrenergic receptor kinase 0.0043 0.0012 0.0012
Plasmodium falciparum centrin-1 0.0154 0.0365 0.11
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.0776
Echinococcus multilocularis neuronal calcium sensor 0.0154 0.0365 0.0365
Trypanosoma cruzi metacaspase 5, putative 0.006 0.0068 0.0068
Echinococcus multilocularis neurogenic locus notch protein 4 0.0043 0.0012 0.0012
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0012 0.0012
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0089 0.0158 0.0158
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.006 0.0068 0.0189
Echinococcus multilocularis glycogen phosphorylase 0.0123 0.0266 0.0266
Schistosoma mansoni calpain-7 (C02 family) 0.0965 0.2943 0.2943
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0043 0.0012 0.0012
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0102 0.0199 0.0199
Trypanosoma brucei proteasome beta 7 subunit 0.0039 0.0001 0.0001
Schistosoma mansoni neprilysin-2 (M13 family) 0.0051 0.0038 0.0038
Schistosoma mansoni notch 0.0043 0.0012 0.0012
Trypanosoma cruzi prolyl endopeptidase 0.2197 0.6857 0.6857
Leishmania major proteasome beta 5 subunit, putative 0.0244 0.065 0.0948
Onchocerca volvulus 0.0102 0.0199 0.0289
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0089 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1187 0.3649 0.5322
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0283 0.0776 0.1132
Entamoeba histolytica cysteine protease, putative 0.0601 0.1787 0.5388
Trypanosoma brucei Calpain-like protein CALP1.3 0.0283 0.0776 0.1132
Trypanosoma brucei calpain-like protein, putative 0.0962 0.2933 0.4278
Brugia malayi cathepsin L precursor 0.0273 0.0744 0.0744
Loa Loa (eye worm) hypothetical protein 0.0043 0.0012 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0273 0.0744 0.0744
Giardia lamblia Cathepsin B precursor 0.0273 0.0744 0.2063
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0039 0.0001 0.0001
Plasmodium falciparum serine repeat antigen 4 0.0273 0.0744 0.2244
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0257 0.0692 0.0692
Echinococcus multilocularis calcium uptake protein 1 0.0157 0.0373 0.0373
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0283 0.0776 0.1132
Entamoeba histolytica hypothetical protein 0.0043 0.0012 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1083 0.3316 0.9194
Trypanosoma brucei centrin, putative 0.0154 0.0365 0.0532
Echinococcus granulosus neuronal calcium sensor 0.0154 0.0365 0.0365
Schistosoma mansoni notch 0.0043 0.0012 0.0012
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.011 0.0225 0.0372
Loa Loa (eye worm) hypothetical protein 0.011 0.0225 0.0225
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0199 0.0199
Brugia malayi Animal haem peroxidase family protein 0.0411 0.1181 0.1181
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0039 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0047 0.0026 0.0026
Trypanosoma brucei Component of motile flagella 41 0.0154 0.0365 0.0532
Schistosoma mansoni cercarial elastase (S01 family) 0.0204 0.0524 0.0524
Trypanosoma brucei prolyl oligopeptidase, putative 0.0892 0.2709 0.3951
Giardia lamblia Hypothetical protein 0.0273 0.0744 0.2063

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 5 uM Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to thrombin receptor (PAR-1) on membranes from CHRF cells ChEMBL. 10360749
IC50 (binding) = 5 uM Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to thrombin receptor (PAR-1) on membranes from CHRF cells ChEMBL. 10360749
Inhibition (functional) = 20 % Evaluated for activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin at 50 uM ChEMBL. 10360749
Inhibition (functional) = 20 % Evaluated for activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin at 50 uM ChEMBL. 10360749

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.