Detailed information for compound 541968

Basic information

Technical information
  • TDR Targets ID: 541968
  • Name: 5,7-dichloro-3-hydroxy-3-[2-(1-naphthyl)-2-ox o-ethyl]indolin-2-one
  • MW: 386.228 | Formula: C20H13Cl2NO3
  • H donors: 2 H acceptors: 3 LogP: 4.41 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cc(Cl)c2c(c1)C(O)(CC(=O)c1cccc3c1cccc3)C(=O)N2
  • InChi: 1S/C20H13Cl2NO3/c21-12-8-15-18(16(22)9-12)23-19(25)20(15,26)10-17(24)14-7-3-5-11-4-1-2-6-13(11)14/h1-9,26H,10H2,(H,23,25)
  • InChiKey: XPVRXXHQUZULBI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5,7-dichloro-3-hydroxy-3-[2-(1-naphthalenyl)-2-oxoethyl]-2-indolinone
  • 5,7-dichloro-3-hydroxy-3-(2-naphthalen-1-yl-2-oxo-ethyl)-1H-indol-2-one
  • 5,7-dichloro-3-hydroxy-3-[2-keto-2-(1-naphthyl)ethyl]oxindole
  • 5,7-dichloro-3-hydroxy-3-(2-naphthalen-1-yl-2-oxoethyl)-1H-indol-2-one
  • 5,7-dichloro-3-hydroxy-3-[2-(1-naphthyl)-2-oxoethyl]-2-indolinone
  • AIDS135500
  • NSC635328
  • NCI60_011740
  • 5,7-Dichloro-3-hydroxy-3-(2-(1-naphthyl)-2-oxoethyl)-1,3-dihydro-2H-indol-2-one
  • AIDS-135500

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Trypanosoma cruzi heat shock protein 85, putative 0.0053 0.0074 0.0071
Brugia malayi beta-lactamase 0.0073 0.011 0.0107
Brugia malayi Endoplasmin precursor 0.0066 0.0098 0.0095
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0015 0.0012
Entamoeba histolytica hypothetical protein 0.0037 0.0045 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.3311 0.5969 0.5968
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0007 0.0061
Brugia malayi RNA recognition motif domain containing protein 0.0192 0.0325 0.0322
Entamoeba histolytica hypothetical protein 0.0535 0.0946 0.0943
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0052 0.0052
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.011 0.0107
Trichomonas vaginalis hypothetical protein 0.0015 0.0005 0.0002
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0052 0.0766
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0021 0.0016 0.0016
Onchocerca volvulus 0.0016 0.0008 0.0081
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0053 0.0074 0.0071
Trypanosoma cruzi cAMP response protein 1, putative 0.0021 0.0016 0.0013
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0013 0.001
Brugia malayi nuclear hormone receptor 0.0041 0.0052 0.0049
Mycobacterium ulcerans hypothetical protein 0.0023 0.0021 0.0692
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0158 0.0265 0.0262
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0027 0.0027 0.0369
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.039 0.0685 0.0682
Brugia malayi nuclear receptor RXR 0.0019 0.0013 0.001
Echinococcus multilocularis heat shock protein 90 0.0053 0.0074 0.0071
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0013 0.0011
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0368 0.0645 0.0862
Brugia malayi Probable ClpP-like protease 0.0079 0.0121 0.0118
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0021 0.0692
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0015 0.0016
Onchocerca volvulus 0.0368 0.0645 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0025 0.0024 0.0256
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Echinococcus granulosus geminin 0.017 0.0287 0.0284
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.039 0.0685 0.0682
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0084 0.0081
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0037 0.0046 0.053
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0021 0.0016 0.0013
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Brugia malayi beta-lactamase family protein 0.0073 0.011 0.0107
Echinococcus granulosus cGMP dependent protein kinase 0.0021 0.0016 0.0014
Brugia malayi Hsp90 protein 0.0027 0.0028 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0011 0.0008
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0008 0.0005
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0006
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0078 0.01
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0013 0.001
Trichomonas vaginalis fk506-binding protein, putative 0.0016 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Plasmodium vivax endoplasmin, putative 0.0066 0.0098 0.14
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0368 0.0645 0.0642
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0015 0.0012
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0015 0.0012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0005 0.0002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0089 0.0086
Schistosoma mansoni intermediate filament proteins 0.0028 0.0028 0.0025
Loa Loa (eye worm) hypothetical protein 0.0092 0.0145 0.0145
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0119 0.0194 0.3698
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0052 0.0049
Echinococcus multilocularis 0.0368 0.0645 0.0643
Trichomonas vaginalis heat shock protein, putative 0.0053 0.0074 0.0071
Entamoeba histolytica heat shock protein 90, putative 0.0066 0.0098 0.0095
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0052 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Brugia malayi nuclear hormone receptor 0.0019 0.0013 0.001
Echinococcus granulosus cGMP dependent protein kinase 1 0.0021 0.0016 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0052 0.0052
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0052 0.0049
Trichomonas vaginalis adenylate cyclase type, putative 0.0015 0.0005 0.0002
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0015 0.0012
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0011 0.0011
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.5538 1 1
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0021 0.0016 0.0018
Entamoeba histolytica hypothetical protein 0.0035 0.0043 0.004
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0467 0.0823 0.082
Echinococcus granulosus heat shock protein 90 0.0066 0.0098 0.0096
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Onchocerca volvulus 0.0049 0.0066 0.0987
Schistosoma mansoni heat shock protein 0.0027 0.0028 0.0025
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.039 0.0685 0.0685
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0089 0.0086
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0025 0.0022
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0052 0.0049
Onchocerca volvulus 0.0017 0.0009 0.0095
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0016 0.0008 0.0443
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0052 0.0052
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0024 0.0804
Trypanosoma brucei chrX additional, unordered contigs 0.0018 0.0011 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0052 0.0052
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0021 0.0692
Trichomonas vaginalis adenylate cyclase type III, putative 0.0015 0.0005 0.0002
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0021 0.0016 0.0014
Leishmania major protein kinase, putative 0.0021 0.0016 0.0013
Treponema pallidum cyclic nucleotide binding protein 0.0021 0.0016 0.026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0089 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0052 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0052 0.0049
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.1235 0.1232
Trichomonas vaginalis PIKK family atypical protein kinase 0.4131 0.7454 0.7453
Schistosoma mansoni lamin 0.0028 0.0028 0.0025
Leishmania major hypothetical protein, conserved 0.0016 0.0007 0.0004
Loa Loa (eye worm) TOPoisomerase family member 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0073 0.011 0.011
Echinococcus granulosus heat shock protein 0.0066 0.0098 0.0096
Brugia malayi heat shock protein 90 0.0066 0.0098 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.3012 0.5428 0.5427
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0119 0.0194 0.0191
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0031 0.0035 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.3007 0.542 0.5419
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0028 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.19 0.3417 0.3415
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0015 0.0012
Entamoeba histolytica protein kinase rad3, putative 0.1068 0.1911 0.1908
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0062 0.0059
Trypanosoma cruzi Flagellar Member 6 0.0021 0.0016 0.0013
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0021 0.0016 0.0197
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0013 0.0013
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0121 1
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0016 0.0013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Schistosoma mansoni cpg binding protein 0.0029 0.0031 0.0028
Echinococcus granulosus lamin dm0 0.0028 0.0028 0.0026
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.001 0.0616
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0052 0.005
Mycobacterium ulcerans polyketide synthase Pks9 0.0017 0.0008 0.0214
Trypanosoma brucei unspecified product 0.004 0.0051 0.0048
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0024 0.0804
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0821 0.1463 0.1461
Mycobacterium ulcerans lipase LipD 0.0073 0.011 0.4131
Loa Loa (eye worm) endoplasmin 0.0066 0.0098 0.0098
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0021 0.0016 0.0013
Entamoeba histolytica hypothetical protein 0.0368 0.0645 0.0642
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0084 0.0081
Schistosoma mansoni fk506 binding protein 0.0016 0.0008 0.0005
Trypanosoma brucei unspecified product 0.0058 0.0084 0.0081
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0121 0.0118
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0084 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.4131 0.7454 0.7453
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.011 0.0107
Giardia lamblia GTOR 0.5538 1 1
Brugia malayi hypothetical protein 0.0037 0.0045 0.0042
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0016 0.0008 0.0101
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0016 0.0008 0.0006
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0579 0.1026 0.1023
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.021 0.0359 0.0356
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0652 0.1158 0.1156
Onchocerca volvulus 0.0017 0.0009 0.0095
Trypanosoma brucei heat shock protein, putative 0.0066 0.0098 0.0095
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0021 0.0016 0.0014
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.002 0.0015 0.0464
Brugia malayi hypothetical protein 0.0238 0.0409 0.0406
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0027 0.0027 0.029
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0052 0.005
Loa Loa (eye worm) hypothetical protein 0.1189 0.213 0.213
Loa Loa (eye worm) RNA binding protein 0.0192 0.0325 0.0325
Brugia malayi jmjC domain containing protein 0.0061 0.0089 0.0086
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0017 0.0014
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0021 0.0016 0.0164
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.039 0.0685 0.0682
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0027 0.0027 0.0912
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0073 0.011 0.011
Trypanosoma brucei Flagellar Member 6 0.0021 0.0016 0.0013
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.001 0.0007
Leishmania major peptidylprolyl isomerase-like protein 0.0119 0.0194 0.0191
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0016 0.0008 0.0006
Leishmania major cyclic nucleotide-binding protein-like protein 0.0021 0.0016 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0006
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0025 0.0024 0.0325
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0016 0.0008 0.0007
Loa Loa (eye worm) phosphatidylinositol 3 0.5538 1 1
Schistosoma mansoni tar DNA-binding protein 0.0192 0.0325 0.0322
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0043 0.0053
Brugia malayi hypothetical protein 0.0021 0.0017 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0006
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0021 0.0016 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0368 0.0645 0.0862
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0016 0.0008 0.0007
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0021 0.0016 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.3311 0.5969 0.5968
Loa Loa (eye worm) hypothetical protein 0.0073 0.011 0.011
Plasmodium vivax heat shock protein 90, putative 0.0027 0.0028 0.0362
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.077 0.1371 0.1369
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0298 0.0518 0.0516
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0007 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0011 0.0008
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0435 0.0765 0.0762
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0005 0.0002
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0072 0.0069
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0579 0.1026 0.1023
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0011 0.0008
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0092 0.0145 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0051 0.0048
Schistosoma mansoni terminal deoxycytidyl transferase 0.0058 0.0084 0.0081
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0015 0.0016
Echinococcus multilocularis lamin dm0 0.0028 0.0028 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.4718 0.8515 0.8515
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.039 0.0685 0.0682
Schistosoma mansoni hypothetical protein 0.0411 0.0723 0.072
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Brugia malayi jmjC domain containing protein 0.0059 0.0086 0.0083
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0021 0.0016 0.0013
Loa Loa (eye worm) phosphatidylinositol 3 0.0368 0.0645 0.0645
Trichomonas vaginalis PIKK family atypical protein kinase 0.4415 0.7967 0.7966
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0015 0.018
Trichomonas vaginalis PIKK family atypical protein kinase 0.3012 0.5428 0.5427
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0015 0.0005 0.0002
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1068 0.1911 0.1908
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0579 0.1026 0.1023
Loa Loa (eye worm) hypothetical protein 0.0699 0.1244 0.1244
Loa Loa (eye worm) hypothetical protein 0.1119 0.2004 0.2004
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.0084 0.0081
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0052 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Loa Loa (eye worm) hypothetical protein 0.0137 0.0227 0.0227
Giardia lamblia DNA damage repair protein 0.0018 0.0011 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0025 0.0326
Onchocerca volvulus 0.0017 0.0009 0.0095
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0119 0.0194 0.0191
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0119 0.0194 0.0191
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0037 0.0046 0.053
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0015 0.0005 0.0002
Schistosoma mansoni nuclear receptor 0.0019 0.0013 0.001
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0158 0.0265 0.0262
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.2313 0.4163 0.4161
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0043 0.004
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0086 0.0083
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0121 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.1888 0.3395 0.3393
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0016 0.0013
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0021 0.0016 0.0013
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0005 0.0002
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0027 0.0027 0.029
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Trypanosoma brucei heat shock protein, putative 0.0066 0.0098 0.0095
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0016 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Treponema pallidum fructose-bisphosphate aldolase 0.0299 0.0519 1
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0092 0.0145 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0052 0.005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Toxoplasma gondii heat shock protein 75, putative 0.0027 0.0028 0.0033
Entamoeba histolytica CAAX amino terminal protease family 0.0019 0.0013 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0006
Mycobacterium ulcerans hypothetical protein 0.0016 0.0008 0.0201
Onchocerca volvulus 0.0073 0.011 0.1672
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0119 0.0194 0.0191
Giardia lamblia Grp94/Hsp90 0.0053 0.0074 0.0071
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0009 0.0089
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0009 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0368 0.0645 0.0642
Trypanosoma brucei heat shock protein 90, putative 0.0066 0.0098 0.0095
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0119 0.0194 0.0191
Mycobacterium ulcerans polyketide synthase 0.0027 0.0027 0.0912
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.0084 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.5538 1 1
Mycobacterium tuberculosis Conserved protein 0.0021 0.0016 0.0164
Echinococcus multilocularis geminin 0.017 0.0287 0.0284
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0013 0.0161
Trichomonas vaginalis adenylate cyclase type III, putative 0.0015 0.0005 0.0002
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0119 0.0194 0.0191
Loa Loa (eye worm) hypothetical protein 0.0073 0.011 0.011
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0021 0.0016 0.0013
Schistosoma mansoni DNA polymerase eta 0.0058 0.0084 0.0081
Plasmodium vivax vivapain-2 0.0017 0.0009 0.0089
Mycobacterium leprae conserved hypothetical protein 0.0073 0.011 0.1672
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0121 0.0118
Echinococcus granulosus hyperpolarization activated cyclic 0.0031 0.0035 0.0033
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0066 0.0063
Brugia malayi beta-NAC-like protein 0.0035 0.0043 0.004
Trichomonas vaginalis heat shock protein, putative 0.0041 0.0052 0.0049
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0021 0.0016 0.0013
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0017
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0043 0.004
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1944 0.3496 0.3494
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0015 0.0012
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0435 0.0765 0.0762
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0016 0.0008 0.0008
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0021 0.0692
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0011 0.0008
Trichomonas vaginalis fk506-binding protein, putative 0.0016 0.0008 0.0005
Entamoeba histolytica CAAX prenyl protease family 0.0092 0.0145 0.0142
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0025 0.0024 0.0325
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0069 0.0069
Mycobacterium ulcerans hypothetical protein 0.0021 0.0016 0.0516
Trichomonas vaginalis PIKK family atypical protein kinase 0.3007 0.542 0.5419
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0084 0.0081
Treponema pallidum cyclic nucleotide binding protein 0.0021 0.0016 0.026
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0103 0.0164 0.0162
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0013 0.001
Schistosoma mansoni zinc finger protein 0.0019 0.0013 0.001
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0021 0.0016 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Trichomonas vaginalis DNA polymerase eta, putative 0.0058 0.0084 0.0081
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0052 0.005
Loa Loa (eye worm) hypothetical protein 0.0079 0.0121 0.0121
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.077 0.1371 0.1369
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0095 0.0092
Toxoplasma gondii CAAX amino terminal protease family protein 0.0019 0.0013 0.0013
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0458 0.0808 0.0805
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0021 0.0018
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Onchocerca volvulus 0.0073 0.011 0.1672
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0043 0.004
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.011 0.1313
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0008 0.0068
Mycobacterium ulcerans integral membrane protein 0.0019 0.0013 0.0385
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0084 0.3105
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Echinococcus multilocularis muscleblind protein 0.0153 0.0255 0.0252
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0016 0.0008 0.0007
Loa Loa (eye worm) RecQ helicase 0.002 0.0015 0.0015
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.0058 0.0084 0.0084
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1944 0.3496 0.3494
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0502 0.0888 0.0885
Trichomonas vaginalis PIKK family atypical protein kinase 0.1888 0.3395 0.3393
Onchocerca volvulus 0.003 0.0033 0.0473
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0062 0.0059
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0062 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0153 0.0255 0.0255
Leishmania major basic transcription factor 3a, putative 0.0035 0.0043 0.004
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0021 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.1068 0.1911 0.1911
Mycobacterium tuberculosis Conserved protein 0.0073 0.011 0.1313
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0021 0.0692
Entamoeba histolytica deoxycytidyl transferase, putative 0.0058 0.0084 0.0081
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.001 0.0007
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0234 0.0231
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0013 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0051 0.0048
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.0243 0.9221
Toxoplasma gondii hypothetical protein 0.0019 0.0013 0.0013
Onchocerca volvulus 0.0017 0.0009 0.0095
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0021 0.0016 0.0018
Mycobacterium tuberculosis Probable integral membrane protein 0.0019 0.0013 0.0122
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.3012 0.5428 0.5427
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0005 0.0002
Echinococcus multilocularis muscleblind protein 1 0.0153 0.0255 0.0252
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0017
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0121 0.4536
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0368 0.0645 0.9421
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0435 0.0765 0.0762
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0005 0.0002
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0013 0.001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1068 0.1911 0.1908
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1888 0.3395 0.3393
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.0243 0.3733
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0021 0.0692
Leishmania major phosphatidylinositol 4-kinase, putative 0.0368 0.0645 0.0642
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0084 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0005 0.0002
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0016 0.0008 0.0007
Leishmania major heat shock protein, putative 0.0027 0.0028 0.0025
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0024 0.0804
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0016 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0025 0.0024 0.0021
Onchocerca volvulus 0.0029 0.0031 0.0434
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0015 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Echinococcus granulosus lamin 0.0028 0.0028 0.0026
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0015 0.0005 0.0002
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.0243 0.2932
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0021 0.0018
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0054 0.0052
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0095 0.0092
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0052 0.005
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0011 0.0011
Plasmodium falciparum heat shock protein 90, putative 0.0027 0.0028 0.0362
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0052 0.005
Schistosoma mansoni hypothetical protein 0.017 0.0287 0.0284
Loa Loa (eye worm) hypothetical protein 0.0046 0.0062 0.0062
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0006
Trichomonas vaginalis immunophilin, putative 0.0119 0.0194 0.0191
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0052 0.005
Loa Loa (eye worm) hypothetical protein 0.0821 0.1463 0.1463
Plasmodium vivax hypothetical protein, conserved 0.0073 0.011 0.1575
Plasmodium falciparum heat shock protein 90 0.0066 0.0098 0.14
Mycobacterium ulcerans beta-lactamase 0.0073 0.011 0.4131
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0021 0.0016 0.0197
Trypanosoma brucei heat shock protein, putative 0.0066 0.0098 0.0095
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0031 0.0035 0.0032
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0005 0.0002
Echinococcus granulosus endoplasmin 0.0053 0.0074 0.0071
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0095 0.0092
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0052 0.0766
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0008 0.0005
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0007 0.0004
Echinococcus multilocularis hyperpolarization activated cyclic 0.0031 0.0035 0.0033
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0368 0.0645 0.0642
Onchocerca volvulus 0.0017 0.0009 0.0095
Echinococcus granulosus cpg binding protein 0.0031 0.0034 0.0031
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0092 0.0145 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0052 0.0052
Brugia malayi jmjC domain containing protein 0.0016 0.0007 0.0004
Echinococcus granulosus dnaJ subfamily B 0.0411 0.0723 0.0721
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0007 0.0004
Echinococcus multilocularis serine protein kinase ATM 0.1068 0.1911 0.1908
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0502 0.0888 0.0885
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0054 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0192 0.0325 0.0322
Loa Loa (eye worm) hypothetical protein 0.0502 0.0888 0.0888
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0008 0.0005
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0368 0.0645 0.0642
Treponema pallidum catabolite gene activator 0.0021 0.0016 0.026
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0052 0.0049
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0025 0.0024 0.0256
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0119 0.0194 0.0194
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0368 0.0645 0.0642
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0007 0.0007
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0086 0.0083
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0017
Trichomonas vaginalis adenylate cyclase type, putative 0.0015 0.0005 0.0002
Schistosoma mansoni immunophilin 0.0103 0.0164 0.0161
Loa Loa (eye worm) heat shock protein 75 0.0027 0.0028 0.0028
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0031 0.0035 0.0033
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.5538 1 1
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0009 0.0006
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0008 0.0077
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0368 0.0645 0.9421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Echinococcus granulosus dna polymerase eta 0.0058 0.0084 0.0081
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0579 0.1026 0.1023
Trichomonas vaginalis PIKK family atypical protein kinase 0.108 0.1932 0.193
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0015 0.0012
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0025 0.0326
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0119 0.0194 0.7344
Trichomonas vaginalis conserved hypothetical protein 0.1189 0.213 0.2128
Trichomonas vaginalis PIKK family atypical protein kinase 0.3715 0.6701 0.67
Trichomonas vaginalis PIKK family atypical protein kinase 0.0368 0.0645 0.0642
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0021 0.0018
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0016 0.0008 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0006
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0007 0.0004
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0021 0.0016 0.0014
Trypanosoma brucei heat shock protein, putative 0.0066 0.0098 0.0095
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.002 0.0016 0.0155
Toxoplasma gondii target of rapamycin (TOR), putative 0.4131 0.7454 1
Schistosoma mansoni phosphatidylinositol 4-kinase 0.039 0.0685 0.0682
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0368 0.0645 0.9421
Plasmodium vivax vivapain-2 0.0017 0.0009 0.0089
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0005 0.0002
Echinococcus multilocularis hyperpolarization activated cyclic 0.0031 0.0035 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0052 0.0049
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1189 0.213 0.2855
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0028 0.0477
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0013 0.0011
Onchocerca volvulus 0.0028 0.0028 0.0397
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0045 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0043 0.004
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0021 0.0016 0.0014
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0103 0.0164 0.0164
Trypanosoma brucei cAMP binding protein, putative 0.0021 0.0016 0.0013
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0021 0.0016 0.0014
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1944 0.3496 0.3494
Trypanosoma cruzi DNA polymerase eta, putative 0.0018 0.0011 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0028
Onchocerca volvulus 0.005 0.007 0.1042
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0016 0.0013
Brugia malayi beta-lactamase family protein 0.0073 0.011 0.0107
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0052 0.0049
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0027 0.0028 0.0025
Echinococcus granulosus voltage gated potassium channel 0.0046 0.0062 0.0059
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0008 0.0005
Trichomonas vaginalis endoplasmin, putative 0.0041 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0006
Leishmania major regulatory subunit of protein kinase a-like protein 0.0021 0.0016 0.0013
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0058 0.0084 0.0081
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0368 0.0645 0.9421
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0035 0.0032
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0013 0.001
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0054 0.0052
Brugia malayi CAAX amino terminal protease family protein 0.0092 0.0145 0.0142
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0013 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0008 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.4131 0.7454 0.7453
Leishmania major hypothetical protein, conserved 0.0026 0.0025 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0035 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.3012 0.5428 0.5427
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0652 0.1158 0.1156
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0021 0.0016 0.0209
Brugia malayi jmjC domain containing protein 0.0016 0.0007 0.0004
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0409 0.0406
Trypanosoma brucei heat shock protein, putative 0.0066 0.0098 0.0095
Echinococcus granulosus muscleblind protein 0.0153 0.0255 0.0252
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0016 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Leishmania major DNA polymerase eta, putative 0.0018 0.0011 0.0008
Plasmodium falciparum heat shock protein 90, putative 0.0027 0.0028 0.0362
Trichomonas vaginalis conserved hypothetical protein 0.0821 0.1463 0.1461
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0013 0.0011
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.039 0.0685 0.0682
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0016 0.0164
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0058 0.0084 0.0081
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0043 0.0043
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Schistosoma mansoni hypothetical protein 0.0016 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.039 0.0685 0.0682
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0013 0.0013
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0368 0.0645 0.0642
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.003 0.0033 0.0371
Toxoplasma gondii hypothetical protein 0.0019 0.0013 0.0013
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.5538 1 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0052 0.005
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0413 0.0725 0.0723
Loa Loa (eye worm) hypothetical protein 0.0076 0.0117 0.0117
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.0013 0.0122
Brugia malayi FAT domain containing protein 0.0821 0.1463 0.1461
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0052 0.005
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.0011 0.0008
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0053 0.0074 0.0869
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0007 0.0004
Trypanosoma brucei unspecified product 0.004 0.0051 0.0048
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0013 0.001
Trypanosoma brucei heat shock protein 90, putative 0.0066 0.0098 0.0095
Trypanosoma brucei protein kinase A regulatory subunit 0.0021 0.0016 0.0013
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0052 0.0049
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0016 0.0008 0.0007
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0021 0.022
Loa Loa (eye worm) FKBP5 protein 0.0119 0.0194 0.0194
Trypanosoma cruzi protein kinase A regulatory subunit 0.0021 0.0016 0.0013
Echinococcus multilocularis GPCR, family 2 0.0016 0.0007 0.0005
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0052 0.005
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0016 0.0008 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0025 0.0326
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0021 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.1488 0.267 0.2668
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0119 0.0194 0.0191
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.011 0.0107
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0045 0.0042
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0062 0.0059
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0031 0.0031
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0435 0.0765 0.0762
Trypanosoma cruzi heat shock protein 85, putative 0.0066 0.0098 0.0095
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0021 0.0018
Trypanosoma cruzi heat shock protein 85, putative 0.0066 0.0098 0.0095
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Chlamydia trachomatis hypothetical protein 0.0019 0.0013 0.0849
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0016 0.0008 0.0005
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0007 0.0004
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.5538 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0009 0.0006
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0016 0.0008 0.0005
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0046 0.0062 0.0059
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0002
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.039 0.0685 0.0682
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0052 0.0049
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0368 0.0645 0.0642
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0409 0.0406
Toxoplasma gondii heat shock protein HSP90 0.0066 0.0098 0.0128
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0025 0.003
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0119 0.0194 0.0191
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0119 0.0194 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Onchocerca volvulus 0.0021 0.0016 0.0209
Schistosoma mansoni immunophilin 0.0119 0.0194 0.0191
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0192 0.0325 0.0322
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0015 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0007 0.0007
Giardia lamblia Hypothetical protein 0.0092 0.0145 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0052 0.0052
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.039 0.0685 0.0915
Plasmodium falciparum cGMP-dependent protein kinase 0.0021 0.0016 0.0197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Echinococcus granulosus transcription factor btf3 0.0035 0.0043 0.004
Leishmania major hypothetical protein, conserved 0.0021 0.0016 0.0013
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0028 0.0028
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Schistosoma mansoni lamin 0.0028 0.0028 0.0025
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0047 0.0064 0.0061
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0368 0.0645 0.0643
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0368 0.0645 0.0642
Plasmodium falciparum endoplasmin, putative 0.0041 0.0052 0.072
Mycobacterium ulcerans hypothetical protein 0.0019 0.0013 0.0385
Plasmodium vivax hypothetical protein 0.0368 0.0645 0.9421
Brugia malayi nuclear receptor NHR-67 0.0019 0.0013 0.001
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0021 0.0016 0.0208
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0511 0.0903 0.09
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0031 0.0035 0.0033
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.039 0.0685 0.0682
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0027 0.0028 0.0384
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Echinococcus granulosus hyperpolarization activated cyclic 0.0031 0.0035 0.0033
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0015 0.0005 0.0002
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0052 0.0049
Loa Loa (eye worm) ctsf protein 0.0017 0.0009 0.0009
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0021 0.0018
Schistosoma mansoni survival motor neuron protein 0.0049 0.0066 0.0063
Schistosoma mansoni hypothetical protein 0.0016 0.0007 0.0004
Schistosoma mansoni DNA helicase recq5 0.002 0.0015 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.1068 0.1911 0.1908
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0006
Trypanosoma cruzi heat shock protein 90, putative 0.0066 0.0098 0.0095
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0121 0.173
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Loa Loa (eye worm) hypothetical protein 0.0368 0.0645 0.0645
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0028 0.0361
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0021 0.0016 0.0013
Entamoeba histolytica recQ family helicase, putative 0.002 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0021 0.0016 0.0018
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0435 0.0765 0.0762
Loa Loa (eye worm) hypothetical protein 0.005 0.0069 0.0069
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.1068 0.1911 0.1908
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0016 0.0008 0.0005
Toxoplasma gondii type I fatty acid synthase, putative 0.0018 0.0011 0.0011
Echinococcus granulosus intermediate filament protein 0.0028 0.0028 0.0026
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.011 0.0107
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.4419 0.7975 0.7974
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0052 0.0049
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0071 0.0068
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Brugia malayi hypothetical protein 0.0017 0.0009 0.0006
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0017 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.5538 1 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0052 0.0766
Brugia malayi jmjC domain containing protein 0.0016 0.0007 0.0004
Mycobacterium ulcerans transmembrane transport protein 0.0021 0.0016 0.0516
Mycobacterium leprae Possible transporter protein 0.0015 0.0005 0.003
Schistosoma mansoni endoplasmin 0.0066 0.0098 0.0095
Loa Loa (eye worm) phosphatidylinositol 3 0.0368 0.0645 0.0645
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.5538 1 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0119 0.0194 0.0191
Mycobacterium ulcerans polyketide synthase Pks13 0.0037 0.0046 0.1666
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0084 0.3105
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0015 0.0012
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0021 0.0016 0.0013
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0119 0.0194 0.0191
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0028 0.0028
Trichomonas vaginalis fk506 binding protein, putative 0.0016 0.0008 0.0005
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.0234 0.0231
Brugia malayi RNA binding protein 0.0192 0.0325 0.0322
Mycobacterium ulcerans thioesterase 0.0021 0.0016 0.0514
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0011 0.0008
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0052 0.005
Trypanosoma brucei heat shock protein 84, putative 0.0027 0.0028 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0017
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0579 0.1026 0.1023
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0007 0.0006
Schistosoma mansoni hypothetical protein 0.0049 0.0066 0.0063
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0054 0.0052
Plasmodium vivax hypothetical protein, conserved 0.0368 0.0645 0.9421
Trichomonas vaginalis PIKK family atypical protein kinase 0.4415 0.7967 0.7966
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0011 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0021 0.0692
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0015 0.0005 0.0002
Echinococcus granulosus cathepsin l1 0.0017 0.0009 0.0006
Entamoeba histolytica cysteine protease, putative 0.0017 0.0009 0.0006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0157 0.0263 0.318
Brugia malayi Egg laying defective protein 4 0.0021 0.0016 0.0013
Giardia lamblia DINP protein human, muc B family 0.0058 0.0084 0.0081
Schistosoma mansoni endoplasmin 0.0066 0.0098 0.0095
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0021 0.0016 0.0164
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0119 0.0194 0.0191
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0021 0.0692
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0009 0.0009
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0511 0.0903 0.09
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0008 0.0068
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.4415 0.7967 0.7966
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.0011 0.0121
Schistosoma mansoni hypothetical protein 0.0021 0.0016 0.0013
Brugia malayi nuclear receptor RXR 0.0021 0.0017 0.0014
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0086 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Echinococcus multilocularis expressed conserved protein 0.0021 0.0016 0.0014
Schistosoma mansoni 60S ribosomal protein L21 0.0025 0.0024 0.0021
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.001 0.0089
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0435 0.0765 0.0762
Loa Loa (eye worm) phosphatidylinositol 3 0.19 0.3417 0.3417
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0119 0.0194 0.0191
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0021 0.0016 0.0013
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0015 0.0013
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0015 0.0012
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.5538 1 1
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0021 0.0016 0.0013
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0016 0.0008 0.0443
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0053 0.0074 0.0071
Brugia malayi tailless protein 0.0019 0.0013 0.001
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.039 0.0685 0.0682
Schistosoma mansoni tar DNA-binding protein 0.0192 0.0325 0.0322
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.039 0.0685 0.0915
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.011 0.1313
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0368 0.0645 0.0642
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0085 0.0082
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0009 0.0006
Leishmania major hypothetical protein, conserved 0.0021 0.0016 0.0013
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0015 0.0005 0.0002
Schistosoma mansoni hypothetical protein 0.017 0.0287 0.0284
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0005 0.0002
Leishmania major DNA damage repair protein, putative 0.0018 0.0011 0.0008
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0016 0.0008 0.0443
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0035 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0015 0.0005 0.0002
Echinococcus granulosus patatin phospholipase domain containing protein 0.0021 0.0016 0.0014
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0033 0.0033
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.108 0.1932 0.193
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Leishmania major mitochondrial DNA polymerase beta 0.0298 0.0518 0.0516
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0017 0.0014
Toxoplasma gondii ABC1 family protein 0.0073 0.011 0.0144
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0021 0.028
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0121 0.1836
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Echinococcus multilocularis heat shock protein 90 0.0066 0.0098 0.0096
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0052 0.0049
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0234 0.0231
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0119 0.0194 0.0191
Loa Loa (eye worm) cysteine protease 0.0017 0.0009 0.0009
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0298 0.0518 0.0516
Echinococcus granulosus single minded 2 0.0015 0.0005 0.0002
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0192 0.0325 0.0325
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0015 0.0015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0007 0.0005
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.0011 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0052 0.0049
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0016 0.0008 0.0005
Echinococcus multilocularis musashi 0.0028 0.0028 0.0026
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0005 0.0002
Onchocerca volvulus 0.0017 0.0009 0.0095
Mycobacterium tuberculosis Probable thioesterase TesA 0.0021 0.0016 0.0163
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0368 0.0645 0.0642
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0015 0.0013
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0009 0.0095
Brugia malayi polk-prov protein 0.0018 0.0011 0.0008
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0092 0.0145 0.0142
Mycobacterium leprae Probable lipase LipE 0.0073 0.011 0.1672
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0069 0.0066
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0009 0.0006
Echinococcus multilocularis dna polymerase eta 0.0058 0.0084 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.011 0.0107
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0368 0.0645 0.0642
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0043 0.0584
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0368 0.0645 0.0643
Echinococcus multilocularis heat shock protein 0.0066 0.0098 0.0096
Trypanosoma brucei cAMP response protein 1, putative 0.0021 0.0016 0.0013
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.011 0.0107
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0013 0.0011
Schistosoma mansoni coup transcription factor 0.0041 0.0052 0.0049
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.001 0.0107
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Loa Loa (eye worm) hypothetical protein 0.0073 0.011 0.011
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0021 0.0016 0.0013
Mycobacterium ulcerans heat shock protein 90 0.0053 0.0074 0.2732
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0007 0.0005
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0072 0.1073
Echinococcus multilocularis bloom syndrome protein 0.002 0.0015 0.0013
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0368 0.0645 0.0862
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0119 0.0194 0.28
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0086 0.0083
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0027 0.0027 0.0369
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0007 0.0005
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0009 0.0089
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0005 0.0002
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0016 0.0013
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0035 0.0032
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.0011 0.0121
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0035 0.0032
Mycobacterium ulcerans hypothetical protein 0.0019 0.0013 0.0385
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0025
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0009 0.0095
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.002 0.0015 0.0188
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Leishmania major phosphatidylinositol 3-kinase, putative 0.1888 0.3395 0.3393
Echinococcus granulosus heat shock protein 90 0.0053 0.0074 0.0071
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.011 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.016 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Entamoeba histolytica CAAX amino terminal protease family 0.0019 0.0013 0.001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0148 0.0246 0.0243
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0043 0.004
Brugia malayi TAR-binding protein 0.0192 0.0325 0.0322
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0043 0.0584
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0502 0.0888 0.0885
Mycobacterium tuberculosis Conserved hypothetical protein 0.0368 0.0645 0.7856
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0119 0.0194 0.0191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0368 0.0645 0.0642
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1944 0.3496 0.3494
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0015 0.0005 0.0002
Echinococcus granulosus serine protein kinase ATM 0.1068 0.1911 0.1908
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0021 0.022
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0024 0.0022 0.0239
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0021 0.0016 0.0014
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.5538 1 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.011 0.0108
Loa Loa (eye worm) hypothetical protein 0.0043 0.0056 0.0056
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1068 0.1911 0.1908
Echinococcus multilocularis voltage gated potassium channel 0.0046 0.0062 0.0059
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0121 0.0158
Loa Loa (eye worm) fatty acid synthase 0.0025 0.0023 0.0023
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0021 0.0016 0.0014
Trichomonas vaginalis fk506-binding protein, putative 0.0119 0.0194 0.0191
Loa Loa (eye worm) phosphatidylinositol 3 0.0368 0.0645 0.0645
Trichomonas vaginalis PIKK family atypical protein kinase 0.1068 0.1911 0.1908
Echinococcus granulosus microtubule associated protein 2 0.0694 0.1235 0.1232
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0191 0.0324 0.0321
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0041 0.0038
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0066 0.0098 0.0095
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0121 0.2284
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.011 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0006
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0025 0.0022
Schistosoma mansoni nuclear receptor 0.0019 0.0013 0.001
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0579 0.1026 0.1023
Mycobacterium ulcerans hypothetical protein 0.0021 0.0016 0.0516
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0058 0.0084 0.0081
Toxoplasma gondii type I fatty acid synthase, putative 0.0028 0.0028 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.3296 0.5942 0.594
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0368 0.0645 0.0642
Giardia lamblia Heat shock protein HSP 90-alpha 0.0053 0.0074 0.0071
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0031 0.0035 0.0033
Leishmania major phosphatidylinositol kinase, putative 0.0368 0.0645 0.0642
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0016 0.0008 0.0081
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0013 0.001
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0021 0.0016 0.0164
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.039 0.0685 0.0682
Leishmania major DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0052 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0031 0.0035 0.0032
Leishmania major hypothetical protein, conserved 0.0073 0.011 0.0107
Trichomonas vaginalis adenylate cyclase type, putative 0.0015 0.0005 0.0002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0058 0.0084 0.0084
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0021 0.0016 0.0013
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0006
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.001 0.0107
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.011 0.0107
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0007 0.0006
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0016 0.0014
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.039 0.0685 1
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0027 0.0028 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.4131 0.7454 0.7453
Trichomonas vaginalis PIKK family atypical protein kinase 0.0699 0.1244 0.1241
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Mycobacterium ulcerans regulatory protein 0.0021 0.0016 0.0516
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.0016 0.0209
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0017 0.0014
Mycobacterium ulcerans hypothetical protein 0.0018 0.0011 0.0317
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0031 0.0035 0.0035
Mycobacterium leprae Polyketide synthase Pks13 0.0037 0.0046 0.0674
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0016 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0007
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0008 0.0077
Plasmodium vivax JmjC domain containing protein 0.0016 0.0007 0.0061
Echinococcus multilocularis tar DNA binding protein 0.0192 0.0325 0.0323
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.011 0.0107
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0119 0.0194 0.0191
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0009 0.0089
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1068 0.1911 0.1908
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0035 0.0032
Loa Loa (eye worm) AGC/PKG protein kinase 0.0021 0.0016 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0045 0.0042
Echinococcus granulosus CAAX prenyl protease 2 0.0092 0.0145 0.0143
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.011 0.4131
Leishmania major cathepsin L-like protease 0.0064 0.0095 0.0092
Toxoplasma gondii Hsp90 domain-containing protein 0.0027 0.0028 0.0033
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0435 0.0765 0.0762
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0007 0.0005
Brugia malayi hypothetical protein 0.0021 0.0017 0.0014
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0009 0.0095
Trypanosoma brucei heat shock protein, putative 0.0066 0.0098 0.0095
Schistosoma mansoni cpg binding protein 0.0031 0.0034 0.0031
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0009 0.0006
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0028 0.0383
Schistosoma mansoni DNA helicase recq1 0.002 0.0015 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0052 0.0049
Loa Loa (eye worm) beta-lactamase 0.0073 0.011 0.011
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0009 0.0006
Onchocerca volvulus 0.0021 0.0016 0.0209
Echinococcus multilocularis cysteine protease 0.0017 0.0009 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.5538 1 1
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0021 0.0016 0.0013
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0052 0.0049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0008 0.0068
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0435 0.0765 0.0762
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0016 0.0008 0.0005
Loa Loa (eye worm) phosphatidylinositol 3 0.0726 0.1291 0.1291
Echinococcus granulosus GPCR family 2 0.0016 0.0007 0.0005
Brugia malayi AMP-binding enzyme family protein 0.003 0.0033 0.003
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0072 0.0843
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0052 0.005
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.011 0.1313
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0052 0.005
Entamoeba histolytica hypothetical protein 0.0368 0.0645 0.0642
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0009 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0013
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.011 0.0107
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0121 0.0158
Brugia malayi hypothetical protein 0.0026 0.0025 0.0022
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.5538 1 1
Leishmania major fk506-binding protein 1-like protein 0.0119 0.0194 0.0191
Onchocerca volvulus 0.0041 0.0052 0.0766
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Leishmania major DNA polymerase eta, putative 0.0058 0.0084 0.0081
Echinococcus multilocularis cpg binding protein 0.0031 0.0034 0.0031
Giardia lamblia Hypothetical protein 0.0016 0.0008 0.0005
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Echinococcus multilocularis lamin 0.0028 0.0028 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Loa Loa (eye worm) heat shock protein 90 0.0066 0.0098 0.0098
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Loa Loa (eye worm) phosphatidylinositol 3 0.0066 0.0098 0.0098
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0007 0.0004
Onchocerca volvulus 0.0017 0.0009 0.0095
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0027 0.0027 0.029
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0158 0.0265 0.0262
Mycobacterium ulcerans hypothetical protein 0.0157 0.0263 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0013 0.0011
Trypanosoma cruzi cAMP binding protein, putative 0.0021 0.0016 0.0013
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0368 0.0645 0.0642
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0016 0.0008 0.0064
Toxoplasma gondii cathepsin CPL 0.0017 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0016 0.0008 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0016 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.4131 0.7454 0.7453
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0052 0.005
Trypanosoma cruzi Heat shock protein 83, putative 0.0066 0.0098 0.0095
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0058 0.0084 0.0081
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0016 0.0008 0.0005
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0028 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0043 0.004
Treponema pallidum heat shock protein 90 0.0053 0.0074 0.1376
Trichomonas vaginalis PIKK family atypical protein kinase 0.3311 0.5969 0.5968
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Entamoeba histolytica hypothetical protein 0.0037 0.0045 0.0042
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0021 0.0016 0.0018
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0008 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0192 0.0325 0.0322
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0017 0.0015
Plasmodium vivax heat shock protein, putative 0.0027 0.0028 0.0362
Trypanosoma cruzi cAMP response protein 1 0.0021 0.0016 0.0013
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0027 0.0027 0.0912
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.1068 0.1911 0.1908
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0435 0.0765 0.0762
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0052 0.005
Trichomonas vaginalis heat shock protein, putative 0.0066 0.0098 0.0095
Mycobacterium leprae conserved hypothetical protein 0.0368 0.0645 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0052 0.0049
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1944 0.3496 0.3494
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0007 0.0004
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0016 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0002
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0031 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0041
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1944 0.3496 0.3494
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.002 0.0015 0.0464
Leishmania major phosphatidylinositol 3-kinase, putative 0.039 0.0685 0.0682
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0052 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.4415 0.7967 0.7966
Plasmodium falciparum phosphatidylinositol 3-kinase 0.039 0.0685 1
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0006
Schistosoma mansoni transcription factor btf3 0.0035 0.0043 0.004
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.0519 0.0516
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0021 0.0016 0.0013
Giardia lamblia Hypothetical protein 0.0368 0.0645 0.0642
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0072 0.0069
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0015 0.0005 0.0002
Entamoeba histolytica hypothetical protein 0.1068 0.1911 0.1908
Trypanosoma cruzi target of rapamycin kinase 3 0.4419 0.7975 0.7974
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.039 0.0685 0.0682
Brugia malayi hypothetical protein 0.0019 0.0013 0.001
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0069 0.0066
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0368 0.0645 0.0643
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0013 0.001
Loa Loa (eye worm) TAR-binding protein 0.0192 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.2611 0.4704 0.4702
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0024 0.0256
Schistosoma mansoni heat shock protein 0.0066 0.0098 0.0095
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0008
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Entamoeba histolytica hypothetical protein 0.0368 0.0645 0.0642
Echinococcus granulosus serine:threonine protein kinase SMG1 0.1068 0.1911 0.1908
Trypanosoma cruzi heat shock protein, putative 0.0027 0.0028 0.0025
Echinococcus multilocularis dnaJ subfamily B 0.0411 0.0723 0.0721
Mycobacterium leprae Probable polyketide synthase Pks1 0.0027 0.0027 0.0369
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.039 0.0685 0.0682
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0072 0.0843
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0021 0.0016 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.3594 0.6482 0.6481
Leishmania major cathepsin L-like protease 0.0064 0.0095 0.0092
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0021 0.0016 0.0013
Trichomonas vaginalis esterase, putative 0.0073 0.011 0.0107
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0016 0.0008 0.0005
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.011 0.1313
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0021 0.0018
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.5538 1 1
Brugia malayi nuclear receptor NHR-88 0.0041 0.0052 0.0049
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0007 0.0004
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0021 0.0016 0.1139
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0013 0.0011
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.19 0.3417 0.3415
Loa Loa (eye worm) fibroinase 0.0017 0.0009 0.0009
Echinococcus granulosus tar DNA binding protein 0.0192 0.0325 0.0323
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0053 0.0074 0.1106
Onchocerca volvulus 0.0019 0.0013 0.0161
Mycobacterium ulcerans hypothetical protein 0.0021 0.0016 0.0516
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0021 0.028
Leishmania major hypothetical protein, unknown function 0.0021 0.0016 0.0013
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0013 0.0161
Brugia malayi ecdysteroid receptor 0.0041 0.0052 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0052 0.0049
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0121 0.173
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0535 0.0946 0.0943
Plasmodium falciparum protease, putative 0.0019 0.0013 0.0147
Trypanosoma brucei heat shock protein, putative 0.0066 0.0098 0.0095
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.007 0.0067
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0005 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0013
Trypanosoma cruzi heat shock protein 90, putative 0.0053 0.0074 0.0071
Trypanosoma brucei DNA damage repair protein, putative 0.0018 0.0011 0.0008
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0121 0.0118
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0031 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.001
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0013 0.0011
Giardia lamblia Fructose-bisphosphate aldolase 0.0299 0.0519 0.0516
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0007 0.0004
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0009 0.0006
Toxoplasma gondii FATC domain-containing protein 0.1068 0.1911 0.256
Entamoeba histolytica hypothetical protein 0.0037 0.0045 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.4415 0.7967 0.7966
Schistosoma mansoni heat shock protein 0.0066 0.0098 0.0095
Brugia malayi CXXC zinc finger family protein 0.0029 0.0031 0.0028
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.0013 0.0122
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0016 0.0008 0.0008
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0016 0.0014
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0015 0.0013
Onchocerca volvulus Fatty acid synthase homolog 0.0045 0.006 0.0892
Entamoeba histolytica heat shock protein 90, putative 0.0066 0.0098 0.0095
Brugia malayi conserved hypotetical protein 0.0019 0.0013 0.001
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0006
Echinococcus multilocularis transcription factor btf3 0.0035 0.0043 0.004
Trichomonas vaginalis heat shock protein, putative 0.0053 0.0074 0.0071
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0027 0.0028 0.0025
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0196 0.0196
Schistosoma mansoni hypothetical protein 0.0821 0.1463 0.1461
Echinococcus granulosus bloom syndrome protein 0.002 0.0015 0.0013
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Echinococcus multilocularis dna polymerase kappa 0.0058 0.0084 0.0081
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0014 0.0004 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.4131 0.7454 0.7453
Onchocerca volvulus 0.0368 0.0645 1
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0013 0.001
Schistosoma mansoni hypothetical protein 0.0016 0.0007 0.0004
Leishmania major hypothetical protein, conserved 0.0021 0.0016 0.0013
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0006
Echinococcus multilocularis cysteine protease 0.0017 0.0009 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Brugia malayi steroid hormone receptor 0.0041 0.0052 0.0049
Echinococcus multilocularis Zinc finger, PHD finger 0.039 0.0685 0.0682
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0095 0.0092
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.039 0.0685 0.0682
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0073 0.011 0.011
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0053 0.0074 0.6022
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0021 0.0016 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.4131 0.7454 0.7453
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0028 0.0025
Brugia malayi Muscleblind-like protein 0.0153 0.0255 0.0252
Echinococcus granulosus FK506 binding protein 2 0.0016 0.0008 0.0006
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0368 0.0645 0.0642
Mycobacterium tuberculosis Conserved protein 0.0073 0.011 0.1313
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.0011 0.0011
Brugia malayi Cyclic-nucleotide gated cation channel 0.0031 0.0035 0.0032
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0298 0.0518 0.0516
Trypanosoma brucei Heat shock protein 83, putative 0.0066 0.0098 0.0095
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0024 0.0022 0.0239
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0015 0.0005 0.0002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0005 0.0002
Trypanosoma brucei hypothetical protein, conserved 0.0018 0.0011 0.0008
Loa Loa (eye worm) phosphatidylinositol 3 0.0368 0.0645 0.0645
Loa Loa (eye worm) DR-78 0.0019 0.0013 0.0013
Giardia lamblia Phosphatidylinositol 4-kinase 0.0368 0.0645 0.0642
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0158 0.0265 0.0265
Schistosoma mansoni voltage-gated potassium channel 0.0173 0.0291 0.0288
Schistosoma mansoni fkbp-rapamycin associated protein 0.1068 0.1911 0.1908
Schistosoma mansoni voltage-gated potassium channel 0.0173 0.0291 0.0288
Echinococcus multilocularis 0.0016 0.0008 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0017 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0009 0.0006
Schistosoma mansoni cpg binding protein 0.0031 0.0034 0.0031
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0153 0.0255 0.0255
Toxoplasma gondii hypothetical protein 0.0027 0.0028 0.0033
Onchocerca volvulus 0.0016 0.0008 0.0081
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0013 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0008 0.0005
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0821 0.1463 0.1461
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0024 0.0804
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.011 0.0108
Entamoeba histolytica hypothetical protein 0.0037 0.0045 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0009 0.0006
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0049 0.0046
Brugia malayi hypothetical protein 0.0019 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.001
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0005 0.0002
Treponema pallidum catabolite gene activator (Crp) 0.0021 0.0016 0.026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0089 0.0086
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0027
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0013 0.0011
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0052 0.005
Loa Loa (eye worm) hypothetical protein 0.0238 0.0409 0.0409
Brugia malayi jmjC domain containing protein 0.0016 0.0007 0.0004
Mycobacterium ulcerans thioesterase TesA 0.0021 0.0016 0.0514
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0005 0.0002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0465 0.0821 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0368 0.0645 0.0642
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0051 0.0048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0008 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.0084 0.0988
Schistosoma mansoni immunophilin 0.0119 0.0194 0.0191
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0016 0.0013
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0052 0.005
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0016 0.0013
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0579 0.1026 0.1023
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0009 0.0006
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.011 0.4131
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0035
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0008 0.0005
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0021 0.0016 0.0164
Loa Loa (eye worm) phosphatidylinositol kinase 0.0368 0.0645 0.0645
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0005 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.3007 0.542 0.5419
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0007 0.0004
Leishmania major protein kinase A regulatory subunit, putative 0.0021 0.0016 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0699 0.1244 0.1241
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0016 0.0008 0.0005
Onchocerca volvulus 0.0028 0.0028 0.0397
Echinococcus multilocularis endoplasmin 0.0053 0.0074 0.0071
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0015 0.018
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Leishmania major phosphatidylinositol 3-related kinase, putative 0.19 0.3417 0.3415
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0021 0.0016 0.0014
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0121 1
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0043 0.004
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0007 0.0004
Brugia malayi intermediate filament protein 0.0028 0.0028 0.0025
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0052 0.0049
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0006
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0119 0.0194 0.0191
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0368 0.0645 0.0643
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0013 0.001
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.077 0.1371 0.1369
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0092 0.0145 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0011 0.0008
Mycobacterium ulcerans hypothetical protein 0.0021 0.0016 0.0516
Leishmania major protein kinase, putative 0.0021 0.0016 0.0013
Mycobacterium tuberculosis Conserved hypothetical protein 0.0058 0.0084 0.0988
Echinococcus granulosus phd:f box containing protein 0.0016 0.0007 0.0004
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.3296 0.5942 0.594
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0015 0.0013
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.011 0.1313
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0021 0.0016 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0025 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.011 0.0107
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0052 0.0049
Giardia lamblia Heat shock protein HSP 90-alpha 0.0066 0.0098 0.0095
Trypanosoma brucei DNA polymerase eta, putative 0.0058 0.0084 0.0081
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0016 0.0008 0.0005
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0119 0.0194 0.28
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0052 0.005
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0148 0.0246 0.0243
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.039 0.0685 0.0682
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.011 0.1313
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0017 0.0008 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.1888 0.3395 0.3393
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0024 0.0021
Plasmodium vivax protease, putative 0.0019 0.0013 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0009 0.0006
Schistosoma mansoni hypothetical protein 0.0016 0.0007 0.0004
Onchocerca volvulus 0.0019 0.0013 0.0161
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0092 0.0145 0.0142
Leishmania major hypothetical protein, unknown function 0.0368 0.0645 0.0642
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0013 0.0011
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0034 0.0041 0.0038
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0015 0.0005 0.0002
Echinococcus multilocularis CAAX prenyl protease 2 0.0092 0.0145 0.0143
Leishmania major heat shock protein 83-1 0.0066 0.0098 0.0095
Onchocerca volvulus 0.0023 0.0021 0.028
Trichomonas vaginalis heat shock protein, putative 0.0053 0.0074 0.0071
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0052 0.0049
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0196 0.0196
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0013 0.0122
Trypanosoma cruzi heat shock protein 85, putative 0.0066 0.0098 0.0095
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0368 0.0645 0.0643
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.1235 0.1232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0095 0.0092
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0007 0.0004
Mycobacterium ulcerans polyketide synthase 0.0025 0.0024 0.0804
Mycobacterium ulcerans hypothetical protein 0.0073 0.011 0.4131
Brugia malayi nuclear receptor NHR-88 0.0019 0.0013 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0025 0.0022
Brugia malayi MH2 domain containing protein 0.012 0.0196 0.0193
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0699 0.1244 0.1241
Brugia malayi N-terminal motif family protein 0.0021 0.0016 0.0013
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0007 0.0004
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0021 0.0016 0.0013
Leishmania major DNA polymerase kappa, putative 0.0018 0.0011 0.0008
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0031 0.0035 0.0035
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.1068 0.1911 0.1908
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0016 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.1888 0.3395 0.3393
Treponema pallidum hypothetical protein 0.0019 0.0013 0.0194
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0007 0.0004
Trypanosoma brucei heat shock protein, putative 0.0066 0.0098 0.0095
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0119 0.0194 0.0191
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0368 0.0645 0.0642
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0021 0.0016 0.0013
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0121 0.4536
Leishmania major hypothetical protein, conserved 0.0469 0.0827 0.0824
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.5538 1 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.001 0.0279
Trypanosoma brucei CAAX amino terminal protease, putative 0.0092 0.0145 0.0142
Plasmodium vivax heat shock protein 86, putative 0.0066 0.0098 0.14
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0021 0.0018
Toxoplasma gondii hypothetical protein 0.0048 0.0066 0.0084
Trypanosoma brucei target of rapamycin kinase 3, putative 0.4419 0.7975 0.7974
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0052
Mycobacterium tuberculosis Conserved protein 0.0073 0.011 0.1313
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0005 0.0002
Onchocerca volvulus 0.0073 0.011 0.1672
Echinococcus multilocularis fk506 binding protein 0.0119 0.0194 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.5538 1 1
Echinococcus granulosus dna polymerase kappa 0.0058 0.0084 0.0081
Leishmania major phosphatidylinositol kinase related protein, putative 0.0368 0.0645 0.0642
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0006
Mycobacterium ulcerans transcriptional regulatory protein 0.0021 0.0016 0.0516
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0031 0.0035 0.0033
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0103 0.0164 0.0162
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0009 0.0006
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0368 0.0645 0.9421
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0084 0.0081
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0013 0.0013
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0018 0.0011 0.01
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.001
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0021 0.0016 0.0197
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0013 0.001
Toxoplasma gondii heat shock protein 90, putative 0.0066 0.0098 0.0128
Schistosoma mansoni hypothetical protein 0.0037 0.0045 0.0042
Leishmania major cathepsin L-like protease 0.0064 0.0095 0.0092
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0368 0.0645 0.0642
Brugia malayi ecdysone receptor 0.0019 0.0013 0.001
Echinococcus granulosus cGMP dependent protein kinase 1 0.0021 0.0016 0.0014
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0017 0.0008 0.0087
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.011 0.1313

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.978 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.819 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.771 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.768 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.766 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.736 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.709 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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