Detailed information for compound 58227

Basic information

Technical information
  • TDR Targets ID: 58227
  • Name: 2-[4-(7-chlorothieno[3,4-b][1,5]benzoxazepin- 4-yl)piperazin-1-yl]ethanol
  • MW: 363.862 | Formula: C17H18ClN3O2S
  • H donors: 1 H acceptors: 1 LogP: 2.06 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Oc2c1csc2
  • InChi: 1S/C17H18ClN3O2S/c18-12-1-2-15-14(9-12)19-17(13-10-24-11-16(13)23-15)21-5-3-20(4-6-21)7-8-22/h1-2,9-11,22H,3-8H2
  • InChiKey: IPBDWMSJZFBYIZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[4-(7-chloro-4-thieno[3,4-b][1,5]benzoxazepinyl)-1-piperazinyl]ethanol
  • 2-[4-(7-chlorothieno[3,4-b][1,5]benzoxazepin-4-yl)piperazino]ethanol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0026 0.0068 0.0128
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0169 0.0397
Brugia malayi Kringle domain containing protein 0.0017 0.0022 0.0041
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.003 0.0091 0.0457
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0209 0.0448
Echinococcus multilocularis acetylcholinesterase 0.0078 0.0352 0.0352
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0076 0.0341 0.064
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0019 0.0032 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0178 0.021
Brugia malayi Nuclear hormone receptor family member nhr-3 0.1001 0.5323 1
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Onchocerca volvulus 0.0026 0.0068 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Toxoplasma gondii kringle domain-containing protein 0.0017 0.0022 0.0316
Echinococcus granulosus nuclear factor of activated T cells 5 0.0085 0.0388 0.0457
Echinococcus multilocularis neuropeptide s receptor 0.0595 0.3137 0.3137
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0026 0.0068 0.6178
Loa Loa (eye worm) TK protein kinase 0.0035 0.0118 0.0221
Echinococcus multilocularis serotonin transporter 0.028 0.1436 0.1436
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.004 0.0197
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0119 0.0568 0.1338
Trypanosoma cruzi polyprenyl synthase, putative 0.003 0.0091 0.0185
Echinococcus granulosus carboxylesterase 5A 0.0078 0.0352 0.0414
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0027 0.0027
Onchocerca volvulus 0.0041 0.0152 0.0286
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.004 0.0579
Brugia malayi GnHR receptor homolog 0.0067 0.029 0.0545
Schistosoma mansoni RAR-like nuclear receptor 0.1001 0.5323 0.6263
Onchocerca volvulus 0.0062 0.0264 0.0497
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.004 0.0071
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0067 0.029 0.0342
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0044 0.0165 0.039
Schistosoma mansoni amine GPCR 0.0067 0.029 0.0342
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0087 0.0175
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0027 0.0051
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0076 0.0341 0.064
Loa Loa (eye worm) nuclear receptor NHR-67 0.0472 0.2474 0.4647
Brugia malayi ecdysteroid receptor 0.1001 0.5323 1
Echinococcus multilocularis dnaJ subfamily B 0.0943 0.5009 0.5009
Plasmodium falciparum LCCL domain-containing protein 0.0045 0.0173 0.3051
Echinococcus granulosus tm gpcr rhodopsin 0.1025 0.545 0.6413
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0047 0.0185 0.4121
Trichomonas vaginalis Ferredoxin 6 0.0026 0.0068 0.0161
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0152 0.0543
Schistosoma mansoni myosin xvIII 0.0067 0.029 0.0342
Brugia malayi hypothetical protein 0.0116 0.0557 0.1046
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0067 0.029 0.0342
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0081 0.019
Echinococcus granulosus sodium and chloride dependent glycine 0.0047 0.0185 0.0218
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0049 0.0115
Echinococcus granulosus retinoic acid receptor rxr beta a 0.1114 0.5933 0.6981
Trypanosoma cruzi target of rapamycin kinase 3 0.0041 0.0152 0.0321
Brugia malayi Cytochrome P450 family protein 0.0041 0.0148 0.0279
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0472 0.2474 0.2474
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0164 0.0164
Echinococcus multilocularis FTZ F1 alpha 0.1001 0.5323 0.5323
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.002 0.004 0.0139
Schistosoma mansoni microtubule-associated protein tau 0.1591 0.85 1
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0026 0.0068 0.0135
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0013
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0164 0.0193
Echinococcus multilocularis tumor protein p63 0.0779 0.4126 0.4126
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.003 0.0091 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0043 0.0102
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0081 0.019
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0023 0.0054 0.0102
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0119 0.0568 0.0669
Entamoeba histolytica ATP-binding cassette protein, putative 0.0014 0.0007 0.0131
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0152 0.0179
Schistosoma mansoni coup transcription factor 0.1001 0.5323 0.6263
Onchocerca volvulus 0.0067 0.029 0.0545
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0152 0.0358
Leishmania major hypothetical protein, conserved 0.0159 0.0787 0.1727
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0002
Loa Loa (eye worm) phospholipase D 0.0022 0.005 0.0095
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0067 0.029 0.0545
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0132 0.0642 0.0755
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.008 0.0189
Brugia malayi ORL1-like opioid receptor 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0022 0.0049 0.0092
Echinococcus granulosus 7TM GPCR rhodopsin 0.0067 0.029 0.0342
Echinococcus multilocularis nuclear receptor nhr 48 0.0472 0.2474 0.2474
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0152 0.0179
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.0185 0.0348
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0026 0.0068 0.0128
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0027 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.029 0.0342
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0119 0.0568 0.0669
Trichomonas vaginalis aldehyde oxidase, putative 0.0802 0.4248 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0178 0.042
Plasmodium vivax amine transporter, putative 0.0047 0.0185 0.3258
Schistosoma mansoni growth hormone secretagogue receptor 0.0067 0.029 0.0342
Echinococcus granulosus tyrosine protein kinase Src42A 0.0044 0.0164 0.0193
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.002 0.004 0.0139
Toxoplasma gondii ferodoxin FD 0.0026 0.0068 0.0999
Mycobacterium ulcerans lipase LipD 0.0041 0.0152 0.0543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0152 0.0358
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0391 0.2034 0.4787
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.003 0.0091 0.1595
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0341 0.0739
Schistosoma mansoni phospholipase D 0.0119 0.057 0.0671
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0005 0.0011
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0152 0.0771
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0119 0.0568 0.0568
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0002
Onchocerca volvulus 0.0047 0.0185 0.0348
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0238 0.121 0.4334
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0529 0.2779 0.3269
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.029 0.029
Schistosoma mansoni acetylcholinesterase 0.0013 0.0001 0.0001
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0472 0.2474 0.291
Onchocerca volvulus Neuropeptide F receptor homolog 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0529 0.2779 0.522
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0087 0.1522
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0026 0.0068 0.0999
Brugia malayi AKH receptor 0.0067 0.029 0.0545
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Trichomonas vaginalis spcc417.12 protein, putative 0.0013 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.002 0.004 0.0139
Schistosoma mansoni hypothetical protein 0.0067 0.029 0.0342
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.019
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0025 0.0025
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.004 0.0071
Loa Loa (eye worm) hypothetical protein 0.0047 0.0185 0.0348
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.0286
Echinococcus granulosus ferredoxin 0.0026 0.0068 0.008
Loa Loa (eye worm) hypothetical protein 0.0057 0.0238 0.0447
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.004 0.0197
Loa Loa (eye worm) TYRA-2 protein 0.0067 0.029 0.0545
Echinococcus multilocularis sex peptide receptor 0.0067 0.029 0.029
Echinococcus granulosus allatostatin A receptor 0.0067 0.029 0.0342
Leishmania major cytochrome p450-like protein 0.0041 0.0148 0.0312
Trichomonas vaginalis Ferredoxin 2 0.0026 0.0068 0.0161
Schistosoma mansoni histamine h1 receptor 0.0067 0.029 0.0342
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.029 0.029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0132 0.0642 0.2298
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0047 0.0185 0.0218
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0022
Trypanosoma cruzi cardiolipin synthetase, putative 0.0041 0.0153 0.0323
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0078 0.0352 0.0414
Loa Loa (eye worm) doublecortin family protein 0.0045 0.0173 0.0326
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0067 0.029 0.0342
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.1001 0.5323 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0047 0.0185 0.0185
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.003 0.0091 0.159
Brugia malayi nuclear receptor NHR-88 0.1001 0.5323 1
Onchocerca volvulus 0.0047 0.0185 0.0348
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0047 0.0185 0.0218
Echinococcus granulosus transcription factor Dp 1 0.0044 0.0168 0.0197
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0178 0.0335
Echinococcus multilocularis tyrosine protein kinase Srms 0.0039 0.0141 0.0141
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0472 0.2474 0.2474
Brugia malayi hypothetical protein 0.0013 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0529 0.2779 0.522
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0067 0.029 0.029
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Echinococcus multilocularis thyroid hormone receptor alpha 0.1001 0.5323 0.5323
Echinococcus granulosus G protein coupled receptor 139 0.0067 0.029 0.0342
Brugia malayi tailless protein 0.0472 0.2474 0.4647
Echinococcus multilocularis dro:myosuppressin receptor 0.0067 0.029 0.029
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0044 0.0164 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.003 0.0091 0.0107
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) carboxylesterase 0.0078 0.0352 0.0661
Brugia malayi Nuclear hormone receptor family member nhr-49 0.1001 0.5323 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0013 0.0001 0.0002
Mycobacterium leprae Probable lipase LipE 0.0041 0.0152 0.3094
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0067 0.029 0.0342
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.014 0.0684 0.3475
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0067 0.029 0.0545
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0045 0.0085
Schistosoma mansoni nuclear receptor 0.0472 0.2474 0.291
Onchocerca volvulus 0.0067 0.029 0.0545
Onchocerca volvulus 0.0013 0.0001 0.0002
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0118 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0012 0.001
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0027 0.0398
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.002 0.004 0.0139
Loa Loa (eye worm) G-protein coupled receptor 0.0067 0.029 0.0545
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.004 0.0197
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0529 0.2779 0.3269
Brugia malayi follicle stimulating hormone receptor 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0077 0.0347 0.0652
Brugia malayi Dopamine receptor protein 2 0.0067 0.029 0.0545
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0023 0.0035
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0026 0.0068 0.0135
Trichomonas vaginalis glucosylceramidase, putative 0.0595 0.3137 0.7383
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.029 0.0342
Schistosoma mansoni amine GPCR 0.0067 0.029 0.0342
Echinococcus multilocularis multidrug resistance associated protein 7 0.0014 0.0007 0.0007
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0049 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.029 0.0342
Schistosoma mansoni biogenic amine receptor 0.0067 0.029 0.0342
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0027 0.0044
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0049 0.0092
Echinococcus multilocularis RUN 0.0045 0.0173 0.0173
Brugia malayi Pre-SET motif family protein 0.0242 0.1234 0.2318
Echinococcus multilocularis phospholipase d3 0.0022 0.005 0.005
Brugia malayi G-protein coupled receptor 0.0067 0.029 0.0545
Brugia malayi Death domain containing protein 0.0017 0.0019 0.0036
Onchocerca volvulus 0.0116 0.0556 0.1045
Loa Loa (eye worm) hypothetical protein 0.0116 0.0556 0.1045
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0132 0.0642 0.1406
Echinococcus granulosus biogenic amine 5HT receptor 0.0067 0.029 0.0342
Trypanosoma cruzi adrenodoxin precursor, putative 0.0026 0.0068 0.0135
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0148 0.0279
Schistosoma mansoni hypothetical protein 0.0943 0.5009 0.5893
Schistosoma mansoni loxhd1 0.0045 0.0173 0.0204
Echinococcus multilocularis allatostatin A receptor 0.0067 0.029 0.029
Loa Loa (eye worm) acetylcholinesterase 1 0.0078 0.0352 0.0661
Echinococcus multilocularis serotonin receptor 0.0067 0.029 0.029
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.002 0.004 0.0139
Brugia malayi Nuclear hormone receptor-like 1 0.0529 0.2779 0.522
Echinococcus multilocularis cpg binding protein 0.007 0.0306 0.0306
Schistosoma mansoni zinc finger protein 0.0472 0.2474 0.291
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.1001 0.5323 0.5323
Schistosoma mansoni opsin-like receptor 0.0067 0.029 0.0342
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0085 0.0388 0.0388
Onchocerca volvulus 0.0045 0.0173 0.0326
Loa Loa (eye worm) hypothetical protein 0.1001 0.5323 1
Schistosoma mansoni aldehyde dehydrogenase 0.014 0.0684 0.0804
Schistosoma mansoni hypothetical protein 0.0195 0.0978 0.1151
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0178 0.0379
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Mycobacterium ulcerans hypothetical protein 0.0041 0.0152 0.0543
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0067 0.029 0.029
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.002 0.004 0.0139
Brugia malayi nuclear receptor NHR-88 0.0472 0.2474 0.4647
Schistosoma mansoni hypothetical protein 0.006 0.0252 0.0296
Trypanosoma brucei unspecified product 0.0015 0.0012 0.001
Echinococcus granulosus lipoxygenase domain containing protein 0.0045 0.0173 0.0204
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0047 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0039 0.014 0.0264
Onchocerca volvulus Glucosylceramidase homolog 0.0391 0.2034 0.3821
Echinococcus granulosus neuropeptide receptor A26 0.0595 0.3137 0.3691
Echinococcus multilocularis sodium and chloride dependent glycine 0.0047 0.0185 0.0185
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.1001 0.5323 0.6263
Trypanosoma brucei C-8 sterol isomerase, putative 0.0852 0.4518 1
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.003 0.0091 0.0322
Loa Loa (eye worm) carboxylesterase 0.0013 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0111 0.0262
Schistosoma mansoni retinoid-x-receptor (RXR) 0.1001 0.5323 0.6263
Giardia lamblia Multidrug resistance-associated protein 1 0.0014 0.0007 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0054 0.0272
Plasmodium vivax SET domain protein, putative 0.0036 0.0123 0.2168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0209 0.0493
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.003 0.0091 0.159
Brugia malayi Tachykinin-like peptides receptor 99D 0.0067 0.029 0.0545
Brugia malayi hypothetical protein 0.0019 0.0031 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-25 0.1001 0.5323 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.019
Plasmodium falciparum cysteine repeat modular protein 1 0.0017 0.0022 0.038
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0341 0.0739
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0027 0.0051
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0152 0.0321
Mycobacterium ulcerans beta-lactamase 0.0041 0.0152 0.0543
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0047 0.0185 0.0348
Echinococcus granulosus tachykinin peptides receptor 99D 0.0067 0.029 0.0342
Schistosoma mansoni retinoic acid receptor RXR 0.1114 0.5933 0.6981
Schistosoma mansoni amine GPCR 0.0067 0.029 0.0342
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0409 0.2133 0.4007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.0238 0.0447
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0152 0.0358
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0119 0.0568 0.1244
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.029 0.0342
Schistosoma mansoni cytochrome P450 0.002 0.004 0.0047
Echinococcus multilocularis phospholipase D1 0.0119 0.057 0.057
Echinococcus multilocularis neuropeptide receptor 0.0067 0.029 0.029
Brugia malayi hypothetical protein 0.0019 0.0032 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0412 0.2147 0.5054
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0049 0.0092
Schistosoma mansoni hypothetical protein 0.0039 0.014 0.0165
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0013 0.0001 0.0001
Schistosoma mansoni sodium/chloride dependent transporter 0.028 0.1436 0.169
Echinococcus multilocularis geminin 0.0195 0.0978 0.0978
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.003 0.0091 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-25 0.1001 0.5323 1
Echinococcus multilocularis fmrfamide receptor 0.0067 0.029 0.029
Loa Loa (eye worm) cytochrome P450 family protein 0.0065 0.0277 0.0521
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0076 0.0341 0.0401
Onchocerca volvulus 0.0041 0.0152 0.0286
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0047 0.0185 0.0218
Mycobacterium tuberculosis Conserved protein 0.0041 0.0152 0.0771
Loa Loa (eye worm) hypothetical protein 0.028 0.1436 0.2698
Trichomonas vaginalis set domain proteins, putative 0.0275 0.1413 0.3327
Schistosoma mansoni neuropeptide receptor 0.0067 0.029 0.0342
Loa Loa (eye worm) hypothetical protein 0.01 0.0468 0.0879
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0044 0.0165 0.2421
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0044 0.0165 0.0311
Giardia lamblia GTOR 0.0052 0.0209 0.3608
Echinococcus granulosus serotonin receptor 0.0067 0.029 0.0342
Echinococcus multilocularis multidrug resistance associated protein 1 0.0014 0.0007 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0081 0.019
Brugia malayi hypothetical protein 0.0529 0.2779 0.522
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0017 0.0022 0.038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.019
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0152 0.0152
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0049 0.0092
Brugia malayi hypothetical protein 0.0041 0.0152 0.0286
Leishmania major hypothetical protein, conserved 0.0026 0.0068 0.0135
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0062 0.0264 0.0497
Brugia malayi hypothetical protein 0.0029 0.0087 0.0163
Echinococcus granulosus neuropeptide s receptor 0.0595 0.3137 0.3691
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.0286
Brugia malayi putative neuropeptide receptor 0.0067 0.029 0.0545
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.1001 0.5323 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0002
Onchocerca volvulus 0.0067 0.029 0.0545
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0044 0.0165 0.0311
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0119 0.0568 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.002 0.004 0.0139
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.003 0.0091 0.0185
Loa Loa (eye worm) intermediate filament protein 0.0062 0.0264 0.0497
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0472 0.2474 0.2474
Schistosoma mansoni nuclear receptor 0.0472 0.2474 0.291
Brugia malayi Protein K4 0.0019 0.0032 0.006
Schistosoma mansoni neuropeptide F-like receptor 0.0067 0.029 0.0342
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0081 0.019
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0152 0.0771
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0014
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0049 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0209 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-14 0.1001 0.5323 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.002 0.004 0.0139
Echinococcus granulosus thyroid hormone receptor alpha 0.0472 0.2474 0.291
Trypanosoma cruzi Emopamil binding protein, putative 0.0159 0.0787 0.1727
Echinococcus granulosus biogenic amine 5HT receptor 0.0067 0.029 0.0342
Loa Loa (eye worm) hypothetical protein 0.0029 0.0085 0.016
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0378 0.1966 0.7044
Loa Loa (eye worm) hypothetical protein 0.0529 0.2779 0.522
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0037
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.004 0.0197
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0142 0.0693 0.0815
Entamoeba histolytica phospholipase D active site domain-containing protein 0.01 0.0468 0.8201
Entamoeba histolytica hypothetical protein 0.0041 0.0152 0.2666
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.1001 0.5323 0.6263
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0152 0.0358
Brugia malayi Nuclear hormone receptor family member nhr-1 0.1001 0.5323 1
Brugia malayi M-phase phosphoprotein, mpp8 0.0116 0.0556 0.1045
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0067 0.029 0.0342
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Echinococcus multilocularis tyrosine protein kinase Blk 0.0039 0.0141 0.0141
Plasmodium falciparum amino acid transporter, putative 0.0047 0.0185 0.3258
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0135 0.0135
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0027 0.0027
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0044 0.0165 0.035
Trichomonas vaginalis glucosylceramidase, putative 0.0595 0.3137 0.7383
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0341 0.0739
Loa Loa (eye worm) hypothetical protein 0.028 0.1436 0.2698
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.1001 0.5323 0.6263
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0047 0.0185 0.0348
Schistosoma mansoni adrenodoxin 0.0026 0.0068 0.008
Loa Loa (eye worm) norepinephrine transporter 0.028 0.1436 0.2698
Plasmodium vivax ferredoxin, putative 0.0026 0.0068 0.1201
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0409 0.2133 0.4007
Loa Loa (eye worm) nuclear hormone receptor 0.0472 0.2474 0.4647
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.004 0.0197
Echinococcus granulosus cytochrome P450 2K1 0.002 0.004 0.0047
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Brugia malayi Polyprenyl synthetase family protein 0.0119 0.0568 0.1068
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0044 0.0165 0.2911
Toxoplasma gondii hypothetical protein 0.0047 0.0185 0.271
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0023 0.0035
Schistosoma mansoni lipoxygenase 0.0199 0.1001 0.1178
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.0138 0.2015
Loa Loa (eye worm) polyprenyl synthetase 0.0119 0.0568 0.1068
Loa Loa (eye worm) melatonin receptor type 1A 0.0067 0.029 0.0545
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0035
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0067 0.029 0.029
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0209 0.0394
Schistosoma mansoni opsin-like receptor 0.0067 0.029 0.0342
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.003 0.0091 0.0322
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0062 0.0264 0.0497
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0409 0.2133 0.251
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0052 0.0209 0.0448
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Brugia malayi intermediate filament protein 0.0062 0.0264 0.0497
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0472 0.2474 0.2474
Brugia malayi putative neuropeptide receptor NPR1 0.0067 0.029 0.0545
Schistosoma mansoni hypothetical protein 0.0018 0.0027 0.0032
Leishmania major farnesyl pyrophosphate synthase 0.0119 0.0568 0.1244
Loa Loa (eye worm) hypothetical protein 0.0509 0.267 0.5016
Brugia malayi Dopamine receptor protein 1 0.0067 0.029 0.0545
Echinococcus granulosus ubiquitin specific protease 41 0.0046 0.0178 0.021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.029 0.0342
Echinococcus granulosus dna polymerase kappa 0.0022 0.0049 0.0057
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0123 0.0594 0.1116
Echinococcus multilocularis GPCR, family 2 0.0018 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0018 0.0027 0.0032
Brugia malayi CHD4 protein 0.0017 0.002 0.0038
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.003 0.0091 0.0091
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.002 0.004 0.0139
Loa Loa (eye worm) beta-lactamase 0.0041 0.0152 0.0286
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.002 0.004 0.0139
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.014 0.0264
Echinococcus granulosus Chromobox protein 3 0.0013 0.000000023302 0.000000027415
Onchocerca volvulus 0.0013 0.0001 0.0002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0046 0.0178 0.0379
Schistosoma mansoni biogenic amine (5HT) receptor 0.0067 0.029 0.0342
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0152 0.3094
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.0286
Brugia malayi hypothetical protein 0.0472 0.2474 0.4647
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.003 0.0091 0.159
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0046 0.0178 0.021
Plasmodium falciparum transporter, putative 0.0047 0.0185 0.3258
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Echinococcus multilocularis neuroligin 0.0013 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.1001 0.5323 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Mycobacterium ulcerans oxidoreductase 0.0026 0.0068 0.0242
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0027 0.0398
Onchocerca volvulus 0.1001 0.5323 1
Trypanosoma brucei cardiolipin synthetase 0.0041 0.0153 0.0323
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0152 0.0771
Brugia malayi Sodium:neurotransmitter symporter family protein 0.028 0.1436 0.2698
Loa Loa (eye worm) hypothetical protein 0.0409 0.2133 0.4007
Schistosoma mansoni Tr4/Tr2 (homologue) 0.1001 0.5323 0.6263
Brugia malayi nuclear hormone receptor 0.1001 0.5323 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.1001 0.5323 0.6263
Schistosoma mansoni sodium-dependent amino acid transporter 0.0047 0.0185 0.0218
Echinococcus multilocularis neuropeptide Y receptor 0.0067 0.029 0.029
Mycobacterium ulcerans aldehyde dehydrogenase 0.014 0.0684 0.2447
Loa Loa (eye worm) hypothetical protein 0.0088 0.0404 0.0758
Echinococcus granulosus tyrosine protein kinase Src64B 0.0044 0.0164 0.0193
Toxoplasma gondii hypothetical protein 0.0047 0.0185 0.271
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.004 0.0197
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.1001 0.5323 1
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0044 0.0165 0.035
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0067 0.029 0.0545
Echinococcus granulosus neuroligin 0.0013 0.0001 0.0001
Giardia lamblia DINP protein human, muc B family 0.0022 0.0049 0.0749
Brugia malayi isocitrate dehydrogenase 0.0018 0.0027 0.0051
Echinococcus granulosus intermediate filament protein 0.0062 0.0264 0.0311
Echinococcus granulosus GPCR family 2 0.0018 0.0027 0.0032
Schistosoma mansoni lamin 0.0062 0.0264 0.0311
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0052 0.0209 0.3672
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0067 0.029 0.0545
Onchocerca volvulus 0.0116 0.0556 0.1045
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0067 0.029 0.0342
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0152 0.0321
Echinococcus granulosus neuropeptide receptor 0.0067 0.029 0.0342
Loa Loa (eye worm) DR-78 0.0472 0.2474 0.4647
Trypanosoma brucei Emopamil binding protein, putative 0.0159 0.0787 0.1727
Giardia lamblia [2Fe-2S] ferredoxin 0.0026 0.0068 0.1094
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0529 0.2779 0.3269
Loa Loa (eye worm) hypothetical protein 0.0509 0.267 0.5016
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Onchocerca volvulus 0.0067 0.029 0.0545
Brugia malayi Protein kinase domain containing protein 0.0018 0.0028 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0209 0.0493
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.029 0.029
Echinococcus granulosus Ankyrin 0.0017 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Echinococcus granulosus dro:myosuppressin receptor 0.0067 0.029 0.0342
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Schistosoma mansoni neuropeptide F-like receptor 0.0067 0.029 0.0342
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0049 0.0245
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0067 0.029 0.0545
Mycobacterium ulcerans hypothetical protein 0.0023 0.0054 0.0191
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0019 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0081 0.019
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0046 0.0178 0.3054
Echinococcus multilocularis ubiquitin specific protease 41 0.0046 0.0178 0.0178
Echinococcus multilocularis phospholipase D 0.0105 0.0496 0.0496
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.1001 0.5323 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.1001 0.5323 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0178 0.0379
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.002 0.004 0.0139
Schistosoma mansoni steroid hormone receptor ad4bp 0.1001 0.5323 0.6263
Schistosoma mansoni polycystin 1-related 0.0045 0.0173 0.0204
Mycobacterium ulcerans electron transfer protein FdxB 0.0026 0.0068 0.0242
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) cytochrome P450 0.002 0.004 0.0074
Schistosoma mansoni neuropeptide f receptor 76f 0.0067 0.029 0.0342
Schistosoma mansoni lamin 0.0062 0.0264 0.0311
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0044 0.0164 0.0164
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0152 0.0358
Brugia malayi nuclear hormone receptor family member nhr-6 0.0472 0.2474 0.4647
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.003 0.0091 1
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0026 0.0068 0.0343
Schistosoma mansoni rab6-interacting 0.0045 0.0173 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0044 0.0165 0.0311
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0036
Onchocerca volvulus 0.0067 0.029 0.0545
Echinococcus multilocularis lamin 0.0062 0.0264 0.0264
Echinococcus multilocularis fmrfamide receptor 0.0067 0.029 0.029
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0052 0.0209 0.0448
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0123 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-19 0.1001 0.5323 1
Echinococcus multilocularis g-protein coupled receptor 0.0067 0.029 0.029
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0153 0.0754 0.27
Echinococcus granulosus Nuclear hormone receptor HR96 0.0472 0.2474 0.291
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.0185 0.0218
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0067 0.029 0.029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.1001 0.5323 1
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0027 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.0391 0.2034 0.4787
Schistosoma mansoni lozenge 0.0064 0.0273 0.0321
Trypanosoma cruzi Emopamil binding protein, putative 0.0159 0.0787 0.1727
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0095 0.0224
Schistosoma mansoni nuclear hormone receptor 0.0472 0.2474 0.291
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0049 0.0092
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.003 0.0091 0.1595
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0049 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Loa Loa (eye worm) CXXC zinc finger family protein 0.0066 0.0286 0.0537
Loa Loa (eye worm) hypothetical protein 0.0046 0.0178 0.0335
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0039 0.0141 0.0166
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0148 0.0312
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0049 0.0194 0.0228
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0179 0.021
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0087 0.1522
Echinococcus granulosus tyrosine protein kinase Lyn 0.0044 0.0164 0.0193
Loa Loa (eye worm) TK protein kinase 0.0039 0.0141 0.0265
Loa Loa (eye worm) polyprenyl synthetase 0.003 0.0091 0.017
Entamoeba histolytica hypothetical protein 0.0041 0.0152 0.2666
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0119 0.0568 0.8317
Echinococcus granulosus lamin dm0 0.0062 0.0264 0.0311
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0148 0.0279
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0088 0.0404 1
Echinococcus granulosus RUN 0.0045 0.0173 0.0204
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0152 0.2678
Echinococcus multilocularis carboxylesterase 5A 0.0078 0.0352 0.0352
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0037 0.0088
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0123 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0152 0.0358
Onchocerca volvulus 0.0013 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.0286
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0119 0.0568 0.2035
Entamoeba histolytica phospholipase D, putative 0.0119 0.057 1
Mycobacterium tuberculosis Conserved protein 0.0041 0.0152 0.0771
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0067 0.029 0.029
Trichomonas vaginalis Ferredoxin 4 0.0026 0.0068 0.0161
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0067 0.029 0.0342
Brugia malayi Nuclear hormone receptor-like 1 0.1001 0.5323 1
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0044 0.0165 0.0165
Leishmania major C-8 sterol isomerase-like protein 0.0852 0.4518 1
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0153 0.0754 0.3833
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.004 0.0071
Echinococcus multilocularis g protein coupled receptor 0.0067 0.029 0.029
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.014 0.0684 0.0804
Trypanosoma cruzi solanesyl-diphosphate synthase 0.003 0.0091 0.0185
Brugia malayi hypothetical protein 0.0047 0.0185 0.0348
Loa Loa (eye worm) hypothetical protein 0.0116 0.0557 0.1046
Brugia malayi multidrug resistance related protein 1 0.0014 0.0007 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.0045 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0023 0.0054 0.0102
Onchocerca volvulus 0.0062 0.0264 0.0497
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.002 0.004 0.0139
Echinococcus multilocularis dna polymerase eta 0.0022 0.0049 0.0049
Brugia malayi G protein-coupled receptor 0.0067 0.029 0.0545
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0049 0.0092
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0025 0.0029
Brugia malayi Phospholipase D. Active site motif family protein 0.0022 0.005 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0123 0.0145
Leishmania major hypothetical protein, conserved 0.0017 0.0022 0.0031
Brugia malayi nuclear receptor NHR-67 0.0472 0.2474 0.4647
Echinococcus multilocularis neuropeptides capa receptor 0.0067 0.029 0.029
Brugia malayi Nuclear hormone receptor E75 0.0472 0.2474 0.4647
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0049 0.0092
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0067 0.029 0.029
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0152 0.0358
Loa Loa (eye worm) hypothetical protein 0.1001 0.5323 1
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.003 0.0091 0.0091
Echinococcus granulosus tyrosine kinase 0.0039 0.0141 0.0166
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0088 0.0404 0.7102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0044 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Schistosoma mansoni hypothetical protein 0.0041 0.0152 0.0179
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0022 0.005 0.0095
Mycobacterium ulcerans endonuclease IV 0.0088 0.0404 0.1444
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0123 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0062 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.0185 0.0348
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0152 0.0286
Schistosoma mansoni rab6-interacting 0.0045 0.0173 0.0204
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0595 0.3137 0.5893
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0027 0.0044
Echinococcus granulosus g-protein coupled receptor 0.0067 0.029 0.0342
Onchocerca volvulus 0.0159 0.0787 0.1478
Loa Loa (eye worm) steroid hormone receptor 0.1001 0.5323 1
Brugia malayi Phospholipase D. Active site motif family protein 0.0041 0.0153 0.0287
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0119 0.0568 0.2889
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0044 0.0164 0.0164
Schistosoma mansoni opsin-like receptor 0.0067 0.029 0.0342
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0054 0.0402
Schistosoma mansoni nuclear receptor nhr-48 0.0472 0.2474 0.291
Brugia malayi RE15519p 0.0067 0.029 0.0545
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.0168 0.0168
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0027 0.0027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0067 0.029 0.0342
Schistosoma mansoni tyrosine kinase 0.0044 0.0164 0.0193
Treponema pallidum hypothetical protein 0.013 0.0631 0.4019
Schistosoma mansoni cellular tumor antigen P53 0.0114 0.0544 0.064
Brugia malayi Steroid receptor seven-up type 2 0.1001 0.5323 1
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0378 0.1966 1
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0152 0.0771
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0041
Schistosoma mansoni thyroid hormone receptor 0.1001 0.5323 0.6263
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0049 0.0092
Schistosoma mansoni glutathione synthetase 0.003 0.0091 0.0107
Schistosoma mansoni hypothetical protein 0.0195 0.0978 0.1151
Loa Loa (eye worm) hypothetical protein 0.0061 0.0258 0.0485
Brugia malayi Nuclear hormone receptor-like 1 0.0529 0.2779 0.522
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0081 0.019
Mycobacterium ulcerans epimerase 0.0023 0.0054 0.0191
Echinococcus multilocularis musashi 0.0062 0.0264 0.0264
Echinococcus granulosus neuropeptide receptor 0.0067 0.029 0.0342
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0028 0.0053
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0076 0.0341 0.5974
Loa Loa (eye worm) hypothetical protein 0.0077 0.0347 0.0652
Trichomonas vaginalis Ferredoxin 7 0.0026 0.0068 0.0161
Brugia malayi Uncoordinated protein 44 0.0017 0.0019 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0595 0.3137 0.7383
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0044 0.0164 0.0164
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0044 0.0164 0.0164
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0026 0.0068 0.0068
Chlamydia trachomatis ferredoxin 0.0026 0.0068 0.0975
Onchocerca volvulus 0.0041 0.0152 0.0286
Loa Loa (eye worm) hypothetical protein 0.0045 0.0173 0.0326
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0047 0.0088
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0026 0.0068 0.0242
Loa Loa (eye worm) neuropeptide F receptor 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.028 0.1436 0.2698
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0047 0.0055
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0119 0.0568 0.1244
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0035
Brugia malayi Intermediate filament tail domain containing protein 0.0062 0.0264 0.0497
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0132 0.0642 0.2298
Schistosoma mansoni hypothetical protein 0.0067 0.029 0.0342
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0047 0.0185 0.0185
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.029 0.0342
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0002
Echinococcus granulosus microtubule associated protein 2 0.1591 0.85 1
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0378 0.1966 0.7044
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Trypanosoma cruzi adrenodoxin precursor, putative 0.0026 0.0068 0.0135
Brugia malayi CXXC zinc finger family protein 0.0066 0.0286 0.0537
Brugia malayi hypothetical protein 0.0045 0.0173 0.0326
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0012 0.001
Schistosoma mansoni lipoxygenase 0.0117 0.0562 0.0661
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0026 0.0068 0.0343
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Schistosoma mansoni cpg binding protein 0.007 0.0306 0.0361
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0052 0.0209 0.0246
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.0286
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0044 0.0165 0.035
Echinococcus multilocularis g protein coupled receptor 0.0067 0.029 0.029
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.0185 0.0218
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0044 0.0165 0.039
Entamoeba histolytica hypothetical protein 0.0041 0.0152 0.2666
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Schistosoma mansoni amine GPCR 0.0067 0.029 0.0342
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0001 0.0001
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0158 0.0186
Schistosoma mansoni amine GPCR 0.045 0.2354 0.277
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0067 0.029 0.0342
Schistosoma mansoni alpha-1 adrenergic receptor 0.0067 0.029 0.0342
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0132 0.0642 0.3263
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0585 0.3084 0.3084
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0002
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0067 0.029 0.029
Brugia malayi neuropeptide F receptor 0.0067 0.029 0.0545
Loa Loa (eye worm) neuropeptide F receptor 0.0067 0.029 0.0545
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0531 0.279 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0019 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-41 0.1001 0.5323 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.1001 0.5323 0.6263
Mycobacterium ulcerans oxidoreductase 0.0026 0.0068 0.0242
Onchocerca volvulus 0.0067 0.029 0.0545
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Plasmodium vivax multidomain scavenger receptor, putative 0.0045 0.0173 0.3051
Schistosoma mansoni multidrug resistance protein 0.0014 0.0007 0.0009
Brugia malayi Doublecortin family protein 0.0045 0.0173 0.0326
Schistosoma mansoni biogenic amine (5HT) receptor 0.0067 0.029 0.0342
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.002 0.0038
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0185 0.3258
Mycobacterium tuberculosis Possible oxygenase 0.0026 0.0068 0.0343
Echinococcus granulosus FTZ F1 alpha 0.1001 0.5323 0.6263
Echinococcus granulosus 7tm_1 domain containing protein 0.0067 0.029 0.0342
Trypanosoma brucei cardiolipin synthetase, putative 0.0041 0.0153 0.0323
Treponema pallidum hypothetical protein 0.0107 0.0508 0.3099
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.0185 0.271
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0529 0.2779 0.522
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0041 0.0152 0.0321
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0027 0.0032
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0097 0.0228
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Schistosoma mansoni intermediate filament proteins 0.0062 0.0264 0.0311
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0049 0.0092
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0019 0.0032 0.0564
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0067 0.029 0.0342
Loa Loa (eye worm) serotonin transporter b 0.028 0.1436 0.2698
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0472 0.2474 0.291
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Loa Loa (eye worm) hypothetical protein 0.0045 0.0173 0.0326
Giardia lamblia MRP-like ABC transporter 0.0014 0.0007 0.0011
Echinococcus multilocularis 0.002 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.1001 0.5323 1
Leishmania major polyprenyl synthase, putative 0.003 0.0091 0.0185
Loa Loa (eye worm) hypothetical protein 0.0078 0.0352 0.0661
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Echinococcus granulosus death domain containing protein 0.0017 0.0019 0.0022
Trypanosoma brucei unspecified product 0.0015 0.0012 0.001
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0076 0.0341 0.0739
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Schistosoma mansoni neuropeptide receptor 0.0067 0.029 0.0342
Echinococcus granulosus neuropeptides capa receptor 0.0067 0.029 0.0342
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.029 0.0342
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0025 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Onchocerca volvulus 0.0047 0.0185 0.0348
Schistosoma mansoni nuclear hormone receptor 0.0472 0.2474 0.291
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0019 0.0036
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0044 0.0164 0.0193
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.002 0.004 0.0139
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Brugia malayi Pre-SET motif family protein 0.0036 0.0123 0.0232
Brugia malayi larval opioid receptor 0.0067 0.029 0.0545
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.003 0.0091 0.0091
Mycobacterium tuberculosis Conserved protein 0.0041 0.0152 0.0771
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.003 0.0091 0.0107
Leishmania major DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Schistosoma mansoni multidrug resistance protein 0.0014 0.0007 0.0009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0067 0.029 0.0342
Trichomonas vaginalis glucosylceramidase, putative 0.0391 0.2034 0.4787
Trypanosoma brucei electron transfer protein, putative 0.0026 0.0068 0.0135
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0049 0.0857
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.008 0.0189
Brugia malayi Cytochrome P450 family protein 0.002 0.004 0.0074
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0067 0.029 0.0342
Loa Loa (eye worm) G-protein coupled receptor 0.0067 0.029 0.0545
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0152 0.0358
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0051
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0023 0.0044
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0067 0.029 0.0545
Echinococcus granulosus neuropeptides capa receptor 0.0067 0.029 0.0342
Echinococcus multilocularis neuropeptide Y receptor 0.0067 0.029 0.029
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0159 0.0787 0.1727
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0119 0.0568 0.2035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.029 0.0342
Mycobacterium ulcerans electron transfer protein 0.0026 0.0068 0.0242
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0052 0.0209 0.0246
Echinococcus granulosus neuropeptide Y receptor 0.0067 0.029 0.0342
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0067 0.029 0.029
Onchocerca volvulus 0.028 0.1436 0.2698
Onchocerca volvulus 0.0114 0.0544 0.1021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.1001 0.5323 0.6263
Brugia malayi nuclear hormone receptor family member odr-7 0.0472 0.2474 0.4647
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0152 0.0771
Loa Loa (eye worm) hypothetical protein 0.0047 0.0185 0.0348
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0044 0.0165 0.0195
Brugia malayi hypothetical protein 0.0529 0.2779 0.522
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0044 0.0165 0.0195
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0103 0.0486 0.0571
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0002
Brugia malayi photoreceptor-specific nuclear receptor 0.1001 0.5323 1
Echinococcus multilocularis somatostatin receptor 0.0067 0.029 0.029
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0123 0.1803
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0041 0.0148 0.0529
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.029 0.0342
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.1001 0.5323 1
Trypanosoma cruzi cardiolipin synthetase, putative 0.0041 0.0153 0.0323
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0472 0.2474 0.4647
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0027 0.0478
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0027 0.0051
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Echinococcus multilocularis g protein coupled receptor 0.0067 0.029 0.029
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0067 0.029 0.0342
Trypanosoma brucei cytochrome P450, putative 0.0041 0.0148 0.0312
Loa Loa (eye worm) hypothetical protein 0.1001 0.5323 1
Schistosoma mansoni aldehyde dehydrogenase 0.014 0.0684 0.0804
Echinococcus granulosus Adrenodoxin mitochondrial 0.0026 0.0068 0.008
Echinococcus granulosus g protein coupled receptor 0.0067 0.029 0.0342
Trichomonas vaginalis esterase, putative 0.0041 0.0152 0.0358
Plasmodium vivax cardiolipin synthetase, putative 0.0019 0.0032 0.0564
Echinococcus multilocularis neuropeptide receptor 0.0067 0.029 0.029
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0153 0.0754 0.27
Leishmania major cardiolipin synthetase, putative 0.0019 0.0032 0.0055
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0041 0.0153 0.2238
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0044 0.0164 0.0193
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.1001 0.5323 0.5323
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.029 0.0342
Toxoplasma gondii ferredoxin, putative 0.0026 0.0068 0.0999
Brugia malayi Phospholipase d protein 1 0.0119 0.057 0.1072
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0152 0.0286
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0049 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Echinococcus multilocularis neuropeptide FF receptor 2 0.0067 0.029 0.029
Onchocerca volvulus 0.0276 0.1414 0.2656
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.002 0.002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0472 0.2474 0.291
Onchocerca volvulus 0.0472 0.2474 0.4647
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0109 0.0128
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0152 0.0152
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0666 0.3515 0.3515
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0595 0.3137 0.5893
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0852 0.4518 0.8488
Entamoeba histolytica ATP-binding cassette protein, putative 0.0014 0.0007 0.0131
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Echinococcus granulosus orexin receptor type 2 0.0067 0.029 0.0342
Toxoplasma gondii ABC1 family protein 0.0041 0.0152 0.2227
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0044 0.0165 0.2911
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.029 0.029
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0046 0.0085
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0067 0.029 0.0342
Loa Loa (eye worm) hypothetical protein 0.0047 0.0185 0.0348
Schistosoma mansoni hypothetical protein 0.002 0.004 0.0047
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0027 0.0032
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0027 0.0027
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.002 0.004 0.0139
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0175
Schistosoma mansoni thyroid hormone receptor 0.1001 0.5323 0.6263
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0002
Trichomonas vaginalis Ferredoxin 3 0.0026 0.0068 0.0161
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0271 0.1388 0.4971
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0472 0.2474 0.4647
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0163
Brugia malayi protein-tyrosine kinase 0.0039 0.0141 0.0265
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0019 0.0019
Leishmania major cytochrome p450-like protein 0.002 0.004 0.0071
Loa Loa (eye worm) hypothetical protein 0.0047 0.0185 0.0348
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.0185 0.271
Onchocerca volvulus 0.0066 0.0286 0.0537
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0027 0.0032
Schistosoma mansoni trans-prenyltransferase 0.003 0.0091 0.0107
Toxoplasma gondii endonuclease IV APN 0.0088 0.0404 0.5906
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.029 0.0342
Brugia malayi orphan nuclear receptor NR2E1 0.0472 0.2474 0.4647
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0435 0.2275 0.4274
Entamoeba histolytica ATP-binding cassette protein, putative 0.0014 0.0007 0.0131
Echinococcus granulosus lamin 0.0062 0.0264 0.0311
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0026 0.0068 0.0128
Loa Loa (eye worm) hypothetical protein 0.0047 0.0185 0.0348
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Brugia malayi Cytochrome P450 family protein 0.0065 0.0277 0.0521
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0158 0.0158
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0037 0.0128 0.024
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0209 0.0394
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.1001 0.5323 1
Loa Loa (eye worm) hypothetical protein 0.0529 0.2779 0.522
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.002 0.004 0.0139
Echinococcus multilocularis tissue type plasminogen activator 0.0017 0.0022 0.0022
Echinococcus granulosus tissue type plasminogen activator 0.0017 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0019 0.0032 0.0055
Echinococcus multilocularis conserved hypothetical protein 0.0798 0.423 0.423
Giardia lamblia Multidrug resistance-associated protein 1 0.0014 0.0007 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.029 0.0342
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.1001 0.5323 0.5323
Echinococcus multilocularis lipoxygenase domain containing protein 0.0045 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0023 0.0054 0.0102
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Brugia malayi nuclear receptor RXR 0.0472 0.2474 0.4647
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0802 0.4248 1
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.003 0.0091 0.0457
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0135 0.0158
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.029 0.029
Onchocerca volvulus 0.0067 0.029 0.0545
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0025 0.0025
Brugia malayi SRC-1 0.0044 0.0164 0.0308
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.1001 0.5323 0.6263
Mycobacterium tuberculosis Probable oxidoreductase 0.0026 0.0068 0.0343
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0152 0.0179
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Leishmania major hypothetical protein, conserved 0.0041 0.0152 0.0321
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0109 0.0204
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.003 0.0091 0.0185
Echinococcus granulosus nuclear receptor 2DBD gamma 0.1001 0.5323 0.6263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0117 0.0276
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0159 0.0787 0.1727
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.0185 0.0218
Trypanosoma cruzi adrenodoxin precursor, putative 0.0026 0.0068 0.0135
Echinococcus multilocularis Protein lozenge 0.0064 0.0273 0.0273
Onchocerca volvulus 0.0045 0.0173 0.0326
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.0185 0.0218
Schistosoma mansoni gliotactin 0.0013 0.0001 0.0001
Echinococcus granulosus dna polymerase eta 0.0022 0.0049 0.0057
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.004 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0138 0.0324
Brugia malayi hypothetical protein 0.0472 0.2474 0.4647
Trypanosoma brucei unspecified product 0.0022 0.0049 0.0092
Brugia malayi Carboxylesterase family protein 0.0078 0.0352 0.0661
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0076 0.0341 0.0341
Echinococcus granulosus tumor protein p63 0.0779 0.4126 0.4854
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0472 0.2474 0.291
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.029 0.0342
Trichomonas vaginalis glucosylceramidase, putative 0.0391 0.2034 0.4787
Brugia malayi neuropeptide F receptor 0.0067 0.029 0.0545
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0044 0.0165 0.035
Trichomonas vaginalis Ferredoxin 1 0.0026 0.0068 0.0161
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0068 0.0135
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.0185 0.271
Onchocerca volvulus 0.0067 0.029 0.0545
Onchocerca volvulus Protein ultraspiracle homolog 0.1001 0.5323 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0529 0.2779 0.2779
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0271 0.1388 0.7058
Echinococcus granulosus peptide allatostatin:somatostatin 0.0067 0.029 0.0342
Echinococcus granulosus acetylcholinesterase 0.0078 0.0352 0.0414
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0178 0.0379
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0014 0.0007 0.0109
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0052 0.0209 0.0448
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.029 0.0342
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0023 0.0023
Onchocerca volvulus 0.0067 0.029 0.0545
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0148 0.0312
Brugia malayi Dopamine receptor 0.0067 0.029 0.0545
Leishmania major cytochrome p450-like protein 0.002 0.004 0.0071
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0109 0.0204
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0242 0.1234 0.2318
Loa Loa (eye worm) hypothetical protein 0.0047 0.0185 0.0348
Echinococcus multilocularis G-protein coupled receptor, putative 0.0067 0.029 0.029
Echinococcus granulosus ecdysone induced protein 78C 0.1001 0.5323 0.6263
Plasmodium falciparum ferredoxin, putative 0.0026 0.0068 0.1201
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0046 0.0178 0.021
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0123 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0095 0.0224
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0052 0.0209 0.3672
Schistosoma mansoni adenoreceptor 0.0067 0.029 0.0342
Entamoeba histolytica protein kinase, putative 0.0035 0.0118 0.2064
Loa Loa (eye worm) hypothetical protein 0.0041 0.0152 0.0286
Schistosoma mansoni multidrug resistance protein 0.0014 0.0007 0.0009
Echinococcus granulosus para nitrobenzyl esterase 0.0013 0.0001 0.0001
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0199 0.1001 0.1001
Echinococcus granulosus geminin 0.0195 0.0978 0.1151
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.002 0.004 0.0139
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.003 0.0091 0.0107
Echinococcus multilocularis ecdysone induced protein 78C 0.1001 0.5323 0.5323
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0119 0.0568 0.1244
Toxoplasma gondii histone lysine methyltransferase SET1 0.0127 0.0612 0.8954
Brugia malayi hypothetical protein 0.0509 0.267 0.5016
Schistosoma mansoni biogenic amine receptor 0.0067 0.029 0.0342
Brugia malayi beta-lactamase 0.0041 0.0152 0.0286
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0152 0.0179
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0002
Echinococcus granulosus acetylcholinesterase 0.0078 0.0352 0.0414
Onchocerca volvulus 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) solute carrier family 6 member 4 0.028 0.1436 0.2698
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0044 0.0164 0.0164
Echinococcus granulosus tyrosine protein kinase Blk 0.0039 0.0141 0.0166
Echinococcus multilocularis neuropeptide receptor A26 0.0595 0.3137 0.3137
Echinococcus granulosus g protein coupled receptor 0.0067 0.029 0.0342
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0026 0.0068 0.0135
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0067 0.029 0.0545
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0097 0.0228
Echinococcus granulosus phospholipase D1 0.0119 0.057 0.0671
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0132 0.0642 0.0755
Loa Loa (eye worm) CYP4Cod1 0.0041 0.0148 0.0279
Onchocerca volvulus 0.0017 0.0022 0.0041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0067 0.029 0.029
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0152 0.0771
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.014 0.0684 0.1499
Echinococcus granulosus multidrug resistance associated protein 7 0.0014 0.0007 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0171
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.002 0.0024
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0002
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0152 0.0771
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.028 0.1436 0.169
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.003 0.0091 0.0457
Schistosoma mansoni cpg binding protein 0.007 0.0306 0.0361
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0143 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Schistosoma mansoni biogenic amine receptor 0.0067 0.029 0.0342
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.0238 0.0447
Mycobacterium ulcerans hypothetical protein 0.013 0.0631 0.2261
Entamoeba histolytica hypothetical protein 0.0014 0.0007 0.0131
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0067 0.029 0.0545
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Onchocerca volvulus 0.0067 0.029 0.0545
Brugia malayi Polyprenyl synthetase family protein 0.003 0.0091 0.017
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0087 0.1522
Echinococcus granulosus sodium and chloride dependent glycine 0.0047 0.0185 0.0218
Giardia lamblia Farnesyl diphosphate synthase 0.0119 0.0568 1
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0852 0.4518 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0468 0.0879
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0118 0.0139
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0152 0.0358
Brugia malayi Nuclear hormone receptor family member nhr-40 0.1001 0.5323 1
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0088 0.0404 0.205
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0087 0.0175
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0088 0.0404 0.7102
Echinococcus granulosus cpg binding protein 0.007 0.0306 0.0361
Echinococcus multilocularis Polycystic kidney disease protein 0.0045 0.0173 0.0173
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.004 0.0197
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0026 0.0068 0.0975
Loa Loa (eye worm) hypothetical protein 0.0029 0.0085 0.016
Echinococcus multilocularis acetylcholinesterase 0.0078 0.0352 0.0352
Echinococcus granulosus phospholipase D 0.0105 0.0496 0.0583
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1025 0.545 0.545
Brugia malayi cytochrome P450 0.002 0.004 0.0074
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0119 0.0568 0.1338
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0043 0.0102
Onchocerca volvulus 0.0067 0.029 0.0545
Schistosoma mansoni DNA polymerase eta 0.0022 0.0049 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.1001 0.5323 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0067 0.029 0.0342
Brugia malayi conserved hypotetical protein 0.0472 0.2474 0.4647
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0078 0.0352 0.0661
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0047 0.0185 0.0348
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0025 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0391 0.2034 0.4787
Loa Loa (eye worm) hypothetical protein 0.0114 0.0544 0.1021
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.003 0.0091 1
Brugia malayi ecdysone receptor 0.0472 0.2474 0.4647
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0152 0.0543
Brugia malayi steroid hormone receptor 0.1001 0.5323 1
Loa Loa (eye worm) SRC-1 0.0044 0.0164 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0038 0.0072
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Loa Loa (eye worm) hypothetical protein 0.0852 0.4518 0.8488
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0044 0.0165 0.2901
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0271 0.1388 0.4971
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0081 0.019
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0019 0.0036
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0049 0.0172
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.029 0.029
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0067 0.029 0.0545
Echinococcus granulosus hypothetical protein 0.0865 0.459 0.5401
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0179 0.021
Brugia malayi sulfakinin receptor protein 0.0067 0.029 0.0545
Treponema pallidum quinoline 2-oxidoreductase 0.0127 0.0615 0.3898
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Echinococcus multilocularis Chromobox protein 3 0.0013 0.000000023302 0.000000023302
Onchocerca volvulus 0.0013 0.0001 0.0002
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.002 0.004 0.0139
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0087 0.1266
Schistosoma mansoni hypothetical protein 0.0018 0.0027 0.0032
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0152 0.0179
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.0185 0.0218
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.002 0.004 0.0139
Echinococcus multilocularis BC026374 protein (S09 family) 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.004 0.0197
Trichomonas vaginalis glucosylceramidase, putative 0.0412 0.2147 0.5054
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0164 0.0193
Echinococcus multilocularis microtubule associated protein 2 0.1591 0.85 0.85
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.003 0.0091 0.1578
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0027 0.0051
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0067 0.029 0.0545
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0123 0.0145
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.002 0.004 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.0391 0.2034 0.4787
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0023 0.0027
Treponema pallidum sodium- and chloride- dependent transporter 0.028 0.1436 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0047 0.0185 0.0185
Loa Loa (eye worm) carboxylesterase 0.0013 0.0001 0.0002
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.003 0.0091 0.1405
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0019 0.0022
Echinococcus granulosus somatostatin receptor 0.0067 0.029 0.0342
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0152 0.0358
Echinococcus granulosus serotonin transporter 0.028 0.1436 0.169
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0027 0.0044
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.1001 0.5323 0.5323
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0025
Trichomonas vaginalis helicase, putative 0.0015 0.001 0.0024
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0023 0.0044
Echinococcus granulosus Polycystic kidney disease protein 0.0045 0.0173 0.0204
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.0238 0.0447
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.004 0.0197
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0132 0.0642 0.0642
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.1001 0.5323 0.5323
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0024
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0052 0.0209 0.0209
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0081 0.019
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0119 0.0568 0.1338
Mycobacterium ulcerans aldehyde dehydrogenase 0.014 0.0684 0.2447
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0023 0.0027
Echinococcus multilocularis para nitrobenzyl esterase 0.0013 0.0001 0.0001
Brugia malayi SET domain containing protein 0.0016 0.0015 0.0027
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.029 0.0342
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0067 0.029 0.0342
Giardia lamblia ABC transporter, putative 0.0014 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0199 0.1001 0.1178
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0052 0.0209 0.0448
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.008 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0081 0.019
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0041 0.0152 0.0321
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0049 0.0172
Brugia malayi ABC transporter transmembrane region family protein 0.0014 0.0007 0.0014
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0026 0.0068 0.0242
Echinococcus multilocularis serotonin receptor 0.0067 0.029 0.029
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0047 0.0185 0.0218
Echinococcus granulosus tyrosine protein kinase Fyn 0.0044 0.0164 0.0193
Trichomonas vaginalis glucosylceramidase, putative 0.0595 0.3137 0.7383
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0027 0.0478
Schistosoma mansoni sodium/chloride dependent transporter 0.0047 0.0185 0.0218
Echinococcus granulosus multidrug resistance associated protein 1 0.0014 0.0007 0.0009
Echinococcus granulosus phospholipase d3 0.0022 0.005 0.0059
Mycobacterium ulcerans oxygenase 0.0026 0.0068 0.0242
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0119 0.0568 1
Schistosoma mansoni tyrosine kinase 0.0044 0.0164 0.0193
Onchocerca volvulus Bile acid receptor homolog 0.1001 0.5323 1
Echinococcus granulosus g protein coupled receptor 0.0067 0.029 0.0342
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.1001 0.5323 0.6263
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.029 0.0342
Trichomonas vaginalis glucosylceramidase, putative 0.0391 0.2034 0.4787
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0049 0.0049
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0472 0.2474 0.4647
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0049 0.0194 0.0364
Entamoeba histolytica ATP-binding cassette protein, putative 0.0014 0.0007 0.0131
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0178 0.021
Entamoeba histolytica ABC transporter, putative 0.0014 0.0007 0.0131
Brugia malayi nuclear hormone receptor 0.0472 0.2474 0.4647
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0036 0.0123 0.0232
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0026 0.0068 0.1201
Onchocerca volvulus 0.0013 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Leishmania major DNA polymerase eta, putative 0.0022 0.0049 0.0092
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0035
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.004 0.0071
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0019 0.0032 0.0564
Onchocerca volvulus 0.0067 0.029 0.0545
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.004 0.0197
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0047 0.0185 0.0218
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.029 0.0342
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.002 0.004 0.0139
Brugia malayi Melatonin receptor type 1A 0.0067 0.029 0.0545
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.0185 0.0348
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.002 0.0024
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0019 0.0032 0.0564
Brugia malayi Carboxylesterase family protein 0.0078 0.0352 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0178 0.042
Entamoeba histolytica phospholipase D, putative 0.0119 0.057 1
Brugia malayi hypothetical protein 0.0067 0.029 0.0545
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0472 0.2474 0.291
Trichomonas vaginalis glucosylceramidase, putative 0.0595 0.3137 0.7383
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.029 0.029
Brugia malayi G-protein coupled receptor 0.0067 0.029 0.0545
Entamoeba histolytica multidrug resistance protein, putative 0.0014 0.0007 0.0131
Onchocerca volvulus 0.0067 0.029 0.0545
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0049 0.0057
Schistosoma mansoni adrenodoxin 0.0026 0.0068 0.008
Echinococcus granulosus lipoxygenase domain containing protein 0.0045 0.0173 0.0204
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0049 0.0057
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.004 0.0071
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.004 0.0197
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.004 0.0197
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0152 0.0321
Schistosoma mansoni nuclear hormone receptor 0.1001 0.5323 0.6263
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0178 0.0178
Chlamydia trachomatis endonuclease IV 0.0088 0.0404 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0178 0.042
Echinococcus granulosus neuropeptide Y receptor 0.0067 0.029 0.0342
Echinococcus multilocularis G protein coupled receptor 139 0.0067 0.029 0.029
Echinococcus granulosus cytoplasmic intermediate filament protein 0.003 0.0091 0.0107
Echinococcus multilocularis ferredoxin adrenodoxin 0.0026 0.0068 0.0068
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.1001 0.5323 0.5323
Onchocerca volvulus 0.0067 0.029 0.0545
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.029 0.029
Schistosoma mansoni netrin receptor unc5 0.0017 0.0019 0.0022
Brugia malayi beta-lactamase family protein 0.0041 0.0152 0.0286
Echinococcus granulosus tm gpcr rhodopsin 0.0666 0.3515 0.4136
Leishmania major ferredoxin, 2fe-2s-like protein 0.0026 0.0068 0.0135
Schistosoma mansoni multidrug resistance protein 0.0014 0.0007 0.0009
Echinococcus multilocularis orexin receptor type 2 0.0067 0.029 0.029
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0027 0.0032
Toxoplasma gondii aldehyde dehydrogenase 0.014 0.0684 1
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0026 0.0068 0.0128
Loa Loa (eye worm) runx1 0.0064 0.0273 0.0513
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.004 0.0197
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0067 0.029 0.029
Echinococcus multilocularis Ankyrin 0.0017 0.002 0.002
Schistosoma mansoni sodium/chloride dependent transporter 0.0047 0.0185 0.0218
Schistosoma mansoni BC026374 protein (S09 family) 0.0013 0.0001 0.0001
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0158 0.0296
Entamoeba histolytica hypothetical protein 0.0041 0.0152 0.2666
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.004 0.0197
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0158 0.0296
Schistosoma mansoni hypothetical protein 0.0067 0.029 0.0342
Brugia malayi Cytochrome P450 family protein 0.0041 0.0148 0.0279
Schistosoma mansoni hypothetical protein 0.0045 0.0173 0.0204
Echinococcus multilocularis neuropeptides capa receptor 0.0067 0.029 0.029
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0023 0.0054 0.0191
Echinococcus granulosus alpha 1A adrenergic receptor 0.0067 0.029 0.0342
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0472 0.2474 0.4647
Loa Loa (eye worm) hypothetical protein 0.0472 0.2474 0.4647
Loa Loa (eye worm) hypothetical protein 0.1001 0.5323 1
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0103 0.0486 0.0571
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0014
Brugia malayi beta-lactamase family protein 0.0041 0.0152 0.0286
Onchocerca volvulus 0.0509 0.267 0.5016
Mycobacterium ulcerans aldehyde dehydrogenase 0.014 0.0684 0.2447
Onchocerca volvulus Putative phospholipase D 0.0022 0.005 0.0095
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0087 0.0175
Loa Loa (eye worm) hypothetical protein 0.1001 0.5323 1
Schistosoma mansoni hypothetical protein 0.0067 0.029 0.0342
Trichomonas vaginalis glucosylceramidase, putative 0.0595 0.3137 0.7383
Echinococcus granulosus BC026374 protein S09 family 0.0013 0.0001 0.0001
Schistosoma mansoni neuroligin 3 (S09 family) 0.0013 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.029 0.0342
Echinococcus granulosus sex peptide receptor 0.0067 0.029 0.0342
Onchocerca volvulus 0.0067 0.029 0.0545
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0019 0.0022
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0178 0.0178
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.004 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0097 0.0228
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.1001 0.5323 1
Echinococcus granulosus nuclear receptor nhr 48 0.0472 0.2474 0.291
Leishmania major solanesyl-diphosphate synthase, putative 0.003 0.0091 0.0185
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0132 0.0642 0.1206
Brugia malayi Serotonin receptor 0.0599 0.3157 0.5931
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.029 0.0342
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.003 0.0091 0.017
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.003 0.0091 0.0091
Echinococcus granulosus nuclear receptor 2DBD gamma 0.1001 0.5323 0.6263
Loa Loa (eye worm) hypothetical protein 0.0529 0.2779 0.522
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0088 0.0404 0.0758
Echinococcus granulosus dnaJ subfamily B 0.0943 0.5009 0.5893
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Brugia malayi Protein kinase domain containing protein 0.0017 0.0019 0.0036
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.003 0.0091 0.0107
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0103 0.0486 0.0571
Brugia malayi Serotonin receptor 0.0067 0.029 0.0545
Schistosoma mansoni neuropeptide receptor 0.0067 0.029 0.0342
Schistosoma mansoni hypothetical protein 0.0018 0.0027 0.0032
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0143 0.0336
Loa Loa (eye worm) hypothetical protein 0.1001 0.5323 1
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0103 0.0486 0.0486
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0802 0.4248 1
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0159 0.0787 0.1727
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0141 0.0141
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.014 0.0684 0.0684
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.0185 0.0218
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.002 0.0023
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0264 0.1353 0.6881
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0044 0.0165 0.0311
Brugia malayi Nuclear hormone receptor family member nhr-19 0.1001 0.5323 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0185 0.0348
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0014 0.0007 0.0014
Leishmania major ferredoxin 2fe-2s-like protein 0.0026 0.0068 0.0135
Schistosoma mansoni neuropeptide receptor 0.0067 0.029 0.0342
Brugia malayi nuclear receptor RXR 0.0529 0.2779 0.522
Echinococcus multilocularis lamin dm0 0.0062 0.0264 0.0264
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0076 0.0341 0.0401
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.029 0.0342
Brugia malayi Nuclear hormone receptor family member nhr-31 0.1001 0.5323 1
Onchocerca volvulus 0.0472 0.2474 0.4647
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0019 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0049 0.0092
Trypanosoma cruzi polyprenyl synthase, putative 0.003 0.0091 0.0185
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0067 0.029 0.029
Echinococcus granulosus fmrfamide receptor 0.0067 0.029 0.0342
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0027 0.0044
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0047 0.0185 0.0218
Brugia malayi hypothetical protein 0.0045 0.0173 0.0326
Brugia malayi Nuclear hormone receptor E75 0.0472 0.2474 0.4647
Loa Loa (eye worm) hypothetical protein 0.0067 0.029 0.0545
Schistosoma mansoni cpg binding protein 0.0066 0.0286 0.0337
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0178 0.3127
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0052 0.0209 0.0448
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.003 0.0091 0.1327

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 2 mg kg-1 Compound was tested for the neuroleptic activity as measured by it's antagonism of d-amphetamine induced lethality in grouped mice(GAL) when administered perorally; 1.4-3.1 ChEMBL. 6110781
ED50 (functional) = 2 mg kg-1 Compound was tested for the neuroleptic activity as measured by it's antagonism of d-amphetamine induced lethality in grouped mice(GAL) when administered perorally; 1.4-3.1 ChEMBL. 6110781
MDD50 (functional) = 19.2 mg kg-1 Reduction in motor activity in rats following p.o. administration. ChEMBL. 6110781
MED (functional) NA 0 mg kg-1 Inhibition of tetrabenazine induced depression in mice was following p.o. administration; Inactive. ChEMBL. 6110781

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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