Detailed information for compound 802687

Basic information

Technical information
  • TDR Targets ID: 802687
  • Name: C530-1125
  • MW: 480.551 | Formula: C26H25FN2O4S
  • H donors: 1 H acceptors: 4 LogP: 4.37 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CCNC(=O)c1ccc2c(c1)N(Cc1ccccc1F)C(=O)c1c(S2(=O)=O)cccc1)C
  • InChi: 1S/C26H25FN2O4S/c1-17(2)13-14-28-25(30)18-11-12-24-22(15-18)29(16-19-7-3-5-9-21(19)27)26(31)20-8-4-6-10-23(20)34(24,32)33/h3-12,15,17H,13-14,16H2,1-2H3,(H,28,30)
  • InChiKey: HHCWBKAHPBAUDS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • NCGC00109640-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0209 0.0475
Trypanosoma brucei unspecified product 0.0027 0.0024 0.0137
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0024 0.0017 0.0034
Entamoeba histolytica protein kinase, putative 0.0033 0.004 0.0216
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.067 0.2712
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.004 0.0318
Onchocerca volvulus 0.0211 0.049 0.1952
Leishmania major long chain fatty Acyl CoA synthetase, putative 0.0023 0.0013 0.0024
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0123 0.0268 0.061
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0023 0.0013 0.0041
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0056 0.0123
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0014 0.0025
Trichomonas vaginalis helicase, putative 0.002 0.0005 0.001
Schistosoma mansoni protein kinase 0.0033 0.004 0.0085
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.017 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0084 0.0169 0.036
Schistosoma mansoni lipoxygenase 0.0115 0.0248 0.0564
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Leishmania major hypothetical protein, conserved 0.0024 0.0017 0.0034
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Mycobacterium tuberculosis Probable fatty acyl-AMP ligase MbtM 0.0023 0.0013 0.0013
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0042 0.0087
Brugia malayi serine/threonine-protein kinase plk-2 0.01 0.0209 0.0444
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0032 0.0041
Trypanosoma cruzi fatty acyl CoA syntetase 1, putative 0.0023 0.0013 0.0023
Echinococcus granulosus acetylcholinesterase 0.007 0.0134 0.0301
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0038 0.0055
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0134 0.0303
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0036 0.0136
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0038 0.0081
Loa Loa (eye worm) hypothetical protein 0.0084 0.0169 0.0354
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0023 0.0013 0.0023
Schistosoma mansoni hypothetical protein 0.0103 0.0216 0.049
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0068 0.0103
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.004 0.0058
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0056 0.0315
Schistosoma mansoni nocturnin 0.0024 0.0017 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0068 0.0145
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 0.0023 0.0013 0.0023
Entamoeba histolytica hypothetical protein 0.0026 0.002 0.0103
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0163 0.0368 0.0841
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0038 0.021
Echinococcus multilocularis GPCR, family 2 0.0277 0.0659 0.1033
Mycobacterium ulcerans Type I modular polyketide synthase 0.0051 0.0085 0.0155
Leishmania major glucose transporter, lmgt3 0.0032 0.0036 0.0078
Plasmodium vivax CDK-related protein kinase 6, putative 0.0437 0.1065 0.6959
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0093 0.0366
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0169 0.0383
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0047 0.0384
Trichomonas vaginalis antibiotic synthetase, putative 0.0163 0.0368 0.1485
Onchocerca volvulus 0.0037 0.005 0.016
Schistosoma mansoni eyes absent homolog 0.0102 0.0215 0.0488
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0084 0.0169 0.0262
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0032 0.0212
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.002 0.0116
Plasmodium vivax JmjC domain containing protein 0.0055 0.0095 0.0586
Loa Loa (eye worm) glutaminase 2 0.0266 0.0631 0.1335
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0054 0.0119
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0067 0.026
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0024 0.0017 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0324 0.1305
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0619 0.1528 0.3508
Trypanosoma brucei polo-like protein kinase 0.01 0.0209 0.1353
Mycobacterium tuberculosis Conserved protein 0.0619 0.1528 0.1528
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.0096 0.0215
Loa Loa (eye worm) hypothetical protein 0.0084 0.0169 0.0354
Leishmania major trypanothione reductase 0.0087 0.0177 0.0406
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0068 0.0151
Schistosoma mansoni nuclear receptor 0.004 0.0056 0.0123
Echinococcus granulosus disco interacting protein 2 0.0023 0.0013 0.0023
Schistosoma mansoni hypothetical protein 0.004 0.0058 0.0126
Trypanosoma brucei trypanothione reductase 0.0087 0.0177 0.1143
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0085 0.017 0.1081
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0036 0.0222
Schistosoma mansoni alpha-glucosidase 0.0563 0.1385 0.318
Brugia malayi MH2 domain containing protein 0.0034 0.0042 0.009
Entamoeba histolytica hypothetical protein 0.0691 0.1709 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.004 0.0318
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0024 0.0017 0.0031
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0507 0.1243 0.2638
Echinococcus granulosus FTZ F1 alpha 0.0084 0.0169 0.0383
Toxoplasma gondii HEAT repeat-containing protein 0.0117 0.0252 0.1633
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 0.0023 0.0013 0.0016
Toxoplasma gondii hypothetical protein 0.0023 0.0013 0.0067
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0167 0.0381 0.2462
Trichomonas vaginalis maltase-glucoamylase, putative 0.0145 0.0324 0.1305
Loa Loa (eye worm) hypothetical protein 0.0619 0.1528 0.3243
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0024 0.0017 0.0096
Trichomonas vaginalis AMP dependent CoA ligase, putative 0.0023 0.0013 0.0041
Brugia malayi jmjC domain containing protein 0.0055 0.0095 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.001
Plasmodium falciparum glutathione reductase 0.003 0.0032 0.0249
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0038 0.0055
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0014 0.0029
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0032 0.0069
Brugia malayi AMP-binding enzyme family protein 0.0038 0.0053 0.0112
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.006 0.0108 0.0165
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0056 0.0185
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0024 0.0017 0.0034
Trichomonas vaginalis esterase, putative 0.0619 0.1528 0.6193
Loa Loa (eye worm) hypothetical protein 0.0054 0.0093 0.0191
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0033 0.0125
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0014 0.0025
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0084 0.0169 0.036
Entamoeba histolytica hypothetical protein 0.0691 0.1709 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.011
Schistosoma mansoni hypothetical protein 0.1246 0.3118 0.7167
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0056 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0085 0.0336
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0023 0.0013 0.0019
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.003 0.0043
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0168 0.0382 0.0381
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0054 0.0094 0.0207
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.067 0.2712
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0096
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0022 0.0011 0.0023
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0054 0.0094 0.0093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0026 0.0026
Brugia malayi nuclear receptor NHR-88 0.0084 0.0169 0.036
Trichomonas vaginalis penicillin-binding protein, putative 0.0619 0.1528 0.6193
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0425 0.1713
Onchocerca volvulus 0.0619 0.1528 0.6181
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0023 0.0013 0.0013
Echinococcus multilocularis chromobox protein 1 0.0068 0.0127 0.0196
Loa Loa (eye worm) hypothetical protein 0.0102 0.0215 0.0452
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0057 0.0393
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0022 0.0011 0.0019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0038 0.0055
Trypanosoma brucei hypothetical protein, conserved 0.0619 0.1528 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0158 0.0357 0.0815
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0084 0.0169 0.0383
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0036 0.022
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.004 0.0318
Mycobacterium leprae Polyketide synthase Pks13 0.0077 0.015 0.0338
Trichomonas vaginalis maltase-glucoamylase, putative 0.0054 0.0093 0.0366
Onchocerca volvulus 0.0087 0.0175 0.067
Schistosoma mansoni peptidase Clp (S14 family) 0.0085 0.017 0.0386
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0054 0.0093 0.0366
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0024 0.0017 0.0034
Brugia malayi beta-lactamase 0.0619 0.1528 0.3246
Loa Loa (eye worm) acyl carrier protein 0.0024 0.0015 0.0027
Echinococcus multilocularis importin 5 0.0022 0.0011 0.0014
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0023 0.0013 0.0023
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0278 0.066 0.1528
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0056 0.0123
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0163 0.0368 0.0758
Plasmodium vivax exodeoxyribonuclease III, putative 0.0024 0.0017 0.0075
Schistosoma mansoni rotamase 0.0033 0.0038 0.0082
Loa Loa (eye worm) hypothetical protein 0.0599 0.1475 0.3131
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.002 0.0069
Echinococcus granulosus thioredoxin glutathione reductase 0.0088 0.0178 0.0404
Leishmania major fatty acid transporter protein-like protein 0.1709 0.4293 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0163 0.0368 0.3424
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.0276 0.1792
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.017 0.0336
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0022 0.0011 0.0013
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0059 0.0089
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.006 0.009
Mycobacterium tuberculosis Polyketide synthase Pks2 0.005 0.0081 0.0081
Loa Loa (eye worm) glutathione reductase 0.0087 0.0177 0.0371
Loa Loa (eye worm) doublecortin family protein 0.0041 0.006 0.0122
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0042 0.0091
Schistosoma mansoni importin-beta 2 0.0022 0.0011 0.002
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0029 0.0223
Echinococcus multilocularis geminin 0.1542 0.3868 0.6087
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0024 0.0017 0.0096
Onchocerca volvulus Deterin homolog 0.0053 0.009 0.0321
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.046 0.1124 0.1765
Loa Loa (eye worm) hypothetical protein 0.0126 0.0276 0.0581
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0011 0.0033
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Echinococcus granulosus cpg binding protein 0.0091 0.0188 0.0426
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.004 0.0085
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Giardia lamblia Fructose-bisphosphate aldolase 0.0568 0.1398 1
Leishmania major hypothetical protein, conserved 0.0109 0.0232 0.0535
Brugia malayi AMP-binding enzyme family protein 0.0163 0.0368 0.0783
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0035
Brugia malayi nuclear receptor RXR 0.0044 0.0068 0.0145
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0038 0.0082
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Mycobacterium tuberculosis Probable lipase LipE 0.0619 0.1528 0.1528
Toxoplasma gondii hypothetical protein 0.0029 0.0029 0.0176
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0186 0.0428 0.0669
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0017 0.0075
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.1709 0.4293 0.4292
Mycobacterium tuberculosis Probable lipase LipD 0.0619 0.1528 0.1528
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0023 0.0013 0.0023
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0051 0.0085 0.0182
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0014 0.0072
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0114 0.026
Echinococcus granulosus jumonji domain containing protein 0.0171 0.039 0.0891
Plasmodium falciparum pyruvate kinase 0.0034 0.0042 0.0341
Leishmania major glucose transporter, lmgt1 0.0032 0.0036 0.0078
Schistosoma mansoni polycystin 1-related 0.0041 0.006 0.0132
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0032 0.0194
Trichomonas vaginalis D-aminoacylase, putative 0.0619 0.1528 0.6193
Loa Loa (eye worm) hypothetical protein 0.0123 0.0268 0.0564
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0042 0.0084
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0216 0.049
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0055 0.0095 0.0212
Loa Loa (eye worm) jmjC domain-containing protein 0.0055 0.0095 0.0196
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0059 0.0197
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0619 0.1528 0.3246
Loa Loa (eye worm) fli-1 protein 0.0213 0.0497 0.1051
Schistosoma mansoni hypothetical protein 0.0024 0.0017 0.0034
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.006 0.0132
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0158 0.0357 0.0815
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0022 0.0011 0.0033
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0134 0.0206
Trypanosoma brucei protein kinase, putative 0.0158 0.0357 0.2323
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0065 0.0121 0.0187
Mycobacterium ulcerans beta-lactamase 0.0619 0.1528 0.3228
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0024 0.0017 0.0023
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0049 0.0079 0.0177
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0056 0.0123
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0619 0.1528 0.3228
Schistosoma mansoni gabp alpha 0.007 0.0134 0.0302
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0014 0.0051
Schistosoma mansoni kinase 0.0052 0.0089 0.0197
Onchocerca volvulus 0.0163 0.0368 0.1457
Brugia malayi isocitrate dehydrogenase 0.0032 0.0038 0.008
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0042 0.0127
Trypanosoma brucei PAB1-binding protein , putative 0.0109 0.0232 0.1504
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.003 0.0063
Trichomonas vaginalis glutaminase, putative 0.0266 0.0631 0.255
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0038 0.023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0034 0.0071
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0024 0.0017 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0145
Brugia malayi conserved hypotetical protein 0.004 0.0056 0.012
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0014 0.0002
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0114 0.0257
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0186 0.0428 0.0991
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0032 0.0032
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.0096 0.0213
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.006 0.0132
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0034 0.0067
Schistosoma mansoni phosphatidylserine receptor 0.0055 0.0095 0.0212
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0084 0.0169 0.0383
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1732 0.435 1
Brugia malayi nuclear hormone receptor 0.0084 0.0169 0.036
Entamoeba histolytica protein kinase, putative 0.0033 0.004 0.0216
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0024 0.0017 0.0096
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.001 0.0031
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0028 0.0026 0.0028
Trypanosoma brucei importin beta-1 subunit, putative 0.0117 0.0252 0.1633
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0014 0.0044
Echinococcus multilocularis snurportin 1 0.1246 0.3118 0.4906
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0216 0.049
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0163 0.0368 0.2399
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0013 0.0024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0691 0.1709 0.3926
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0065 0.0121 0.1089
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Schistosoma mansoni ets-related 0.0213 0.0497 0.1137
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0507 0.1243 0.2854
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0425 0.1713
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0507 0.1243 0.2854
Schistosoma mansoni protein kinase 0.0033 0.004 0.0085
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0211 0.049 0.049
Leishmania major hypothetical protein, conserved 0.0024 0.0017 0.0034
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0055 0.0095 0.0605
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0037 0.005 0.0311
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0137 0.0304 0.0693
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0032 0.0194
Toxoplasma gondii type I fatty acid synthase, putative 0.0036 0.0048 0.0297
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0276 0.0629
Schistosoma mansoni alpha glucosidase 0.0145 0.0324 0.0739
Brugia malayi cDNA sequence BC018371 0.0023 0.0013 0.0027
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0047 0.0288
Plasmodium falciparum glutathione reductase 0.0087 0.0177 0.1616
Plasmodium falciparum JmjC domain-containing protein, putative 0.0055 0.0095 0.0842
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0023 0.0013 0.0013
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.002 0.0028
Echinococcus multilocularis expressed protein 0.0033 0.0038 0.0056
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0054 0.0081
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0032 0.0068
Trypanosoma brucei glucose transporter, putative 0.0032 0.0036 0.022
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0115 0.0248 0.0386
Trypanosoma brucei fatty acyl CoA synthetase 2 0.0023 0.0013 0.0067
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0056 0.0218
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Trypanosoma cruzi hypothetical protein, conserved 0.0619 0.1528 0.3508
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0056 0.0123
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0057 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Loa Loa (eye worm) MH2 domain-containing protein 0.0502 0.123 0.261
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0023 0.0013 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.045 0.1816
Echinococcus granulosus transportin 1 0.0022 0.0011 0.002
Echinococcus multilocularis nuclear receptor nhr 48 0.004 0.0056 0.0084
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0056 0.0123
Echinococcus multilocularis chromobox protein 1 0.0068 0.0127 0.0196
Brugia malayi hypothetical protein 0.004 0.0056 0.012
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.207 0.4756
Schistosoma mansoni hypothetical protein 0.0123 0.0268 0.061
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0042 0.0089
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0022 0.0011 0.0019
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.006 0.051
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.001
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0054 0.0081
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0022 0.0011 0.0023
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.004 0.0085
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0056 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.045 0.1816
Plasmodium falciparum protein kinase 6 0.0437 0.1065 1
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0034 0.0049
Onchocerca volvulus Alhambra homolog 0.0123 0.0268 0.1048
Schistosoma mansoni nuclear hormone receptor 0.004 0.0056 0.0123
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0055 0.0095 0.0605
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0011 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0127 0.0506
Trichomonas vaginalis ran, putative 0.0065 0.0121 0.0481
Brugia malayi Smad1 0.0034 0.0042 0.009
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0046 0.0071 0.0615
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0209 0.0475
Schistosoma mansoni acetyl-CoA synthetase 0.0163 0.0368 0.0841
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0011 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.001
Trypanosoma brucei acetyl-CoA synthetase, truncated 0.0023 0.0013 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0084 0.0169 0.036
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Schistosoma mansoni rab6-interacting 0.0041 0.006 0.0132
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0134 0.0301
Schistosoma mansoni nuclear hormone receptor 0.004 0.0056 0.0123
Echinococcus multilocularis flap endonuclease 1 0.0025 0.002 0.0027
Schistosoma mansoni smad1 5 8 and 0.0034 0.0042 0.0091
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0056 0.0123
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0024 0.0017 0.0034
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0013 0.0027
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0035 0.0051
Echinococcus multilocularis deoxyribonuclease 1 2 0.0024 0.0017 0.0023
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0023 0.0013 0.0023
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0032 0.0069
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0023 0.0013 0.0067
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0054 0.0094 0.0172
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.017 0.11
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0158 0.0357 0.0815
Trypanosoma brucei glucose transporter 2A 0.0032 0.0036 0.022
Echinococcus multilocularis RUN 0.0041 0.006 0.009
Brugia malayi PHD-finger family protein 0.0123 0.0268 0.0569
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0026 0.0022 0.003
Echinococcus multilocularis pyruvate kinase 0.0034 0.0042 0.0062
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 0.0023 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0066
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0053 0.009 0.0137
Echinococcus granulosus acetylcholinesterase 0.007 0.0134 0.0301
Schistosoma mansoni pyruvate kinase 0.0034 0.0042 0.009
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.1872 0.4706 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0013 0.0013
Schistosoma mansoni chromobox protein 0.0068 0.0127 0.0287
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0145 0.0324 0.0683
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0053 0.009 0.02
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0033 0.0125
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0032 0.0194
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0024 0.0017 0.0085
Loa Loa (eye worm) hypothetical protein 0.0084 0.0169 0.0354
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0085
Loa Loa (eye worm) hypothetical protein 0.0037 0.005 0.0101
Brugia malayi MH1 domain containing protein 0.0034 0.0042 0.009
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0619 0.1528 0.1528
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0023 0.0013 0.0067
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0024 0.0017 0.0096
Echinococcus granulosus sodium:myo inositol cotransporter 0.0037 0.005 0.0109
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.004 0.0078
Onchocerca volvulus 0.0989 0.2465 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0036 0.0136
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0163 0.0368 0.0841
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0324 0.1305
Brugia malayi Latrophilin receptor protein 2 0.0277 0.0659 0.14
Plasmodium vivax ataxin-2 like protein, putative 0.0109 0.0232 0.1486
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0026 0.0049
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.0306 0.1989
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0278 0.066 0.1379
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0011 0.0033
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0042 0.0237
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.004 0.0242
Plasmodium vivax acyl-CoA synthetase, putative 0.0023 0.0013 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0036 0.0136
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Schistosoma mansoni sodium/solute symporter 0.0037 0.005 0.0109
Trichomonas vaginalis antibiotic synthetase, putative 0.0163 0.0368 0.1485
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0036 0.022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD11 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0013 0.0013
Schistosoma mansoni jumonji/arid domain-containing protein 0.0211 0.0491 0.1124
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.01 0.0209 0.0439
Schistosoma mansoni hypothetical protein 0.0053 0.009 0.02
Echinococcus granulosus chromobox protein 1 0.0068 0.0127 0.0287
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0054 0.0094 0.0172
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0095 0.0196 0.0784
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.0232 0.2135
Onchocerca volvulus Putative neutral sphingomyelinase 0.0024 0.0017 0.0026
Echinococcus granulosus importin subunit beta 1 0.0117 0.0252 0.0573
Schistosoma mansoni steroid hormone receptor ad4bp 0.0084 0.0169 0.0383
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0022 0.0011 0.0019
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0053 0.009 0.0191
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0507 0.1243 0.2854
Loa Loa (eye worm) hypothetical protein 0.0044 0.0068 0.014
Onchocerca volvulus 0.004 0.0056 0.0185
Giardia lamblia DINP protein human, muc B family 0.0039 0.0054 0.0369
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0036 0.0136
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0323 0.0737
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0032 0.0068
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0065 0.0121 0.0758
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0024 0.0017 0.0059
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.046 0.1124 0.2579
Leishmania major hypothetical protein, unknown function 0.0023 0.0013 0.0024
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0054 0.0088
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0042 0.0062 0.0062
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1246 0.3118 0.6625
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0114 0.0216
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0084 0.0169 0.0354
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0096
Mycobacterium ulcerans thioesterase 0.0043 0.0064 0.0109
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0038 0.023
Leishmania major importin beta-1 subunit, putative 0.0095 0.0196 0.045
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0042 0.0062
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0334 0.0521
Giardia lamblia hypothetical protein 0.0024 0.0017 0.0105
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0022 0.0011 0.0019
Schistosoma mansoni lipoxygenase 0.0041 0.006 0.0132
Loa Loa (eye worm) DR-78 0.004 0.0056 0.0114
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0032 0.0069
Trypanosoma brucei importin beta-1 subunit, putative 0.0117 0.0252 0.1633
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0022 0.0011 0.0019
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0065 0.0121 0.0849
Onchocerca volvulus 0.0252 0.0595 0.2379
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0012 0.0025
Brugia malayi Steroid receptor seven-up type 2 0.0084 0.0169 0.036
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0167 0.0381 0.2478
Toxoplasma gondii thioredoxin reductase 0.0087 0.0177 0.1143
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0163 0.0368 0.0758
Brugia malayi AMP-binding enzyme family protein 0.1872 0.4706 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0047 0.0101
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0084 0.0169 0.0262
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0085
Loa Loa (eye worm) acetyltransferase 0.0149 0.0334 0.0704
Mycobacterium ulcerans polyketide synthase Pks9 0.0034 0.0041 0.0061
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0056 0.0352
Brugia malayi orphan nuclear receptor NR2E1 0.004 0.0056 0.012
Schistosoma mansoni flap endonuclease-1 0.0023 0.0014 0.0025
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0038 0.0038
Giardia lamblia Long chain fatty acid CoA ligase 5 0.0023 0.0013 0.0073
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0282 0.067 0.142
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0023 0.0013 0.0041
Leishmania major GTP-binding protein, putative 0.0065 0.0121 0.0276
Trypanosoma cruzi importin beta-1 subunit, putative 0.0095 0.0196 0.0444
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0085
Trypanosoma brucei unspecified product 0.0027 0.0024 0.0137
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0084 0.0169 0.0383
Brugia malayi AMP-binding enzyme family protein 0.0163 0.0368 0.0783
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0029 0.012
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0024 0.0017 0.0034
Trichomonas vaginalis AMP dependent CoA ligase, putative 0.0023 0.0013 0.0041
Onchocerca volvulus 0.018 0.0413 0.164
Schistosoma mansoni ran 0.0065 0.0121 0.0273
Loa Loa (eye worm) hypothetical protein 0.0033 0.004 0.0078
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Echinococcus granulosus thyroid hormone receptor alpha 0.004 0.0056 0.0123
Echinococcus multilocularis pyruvate kinase 0.0027 0.0024 0.0033
Plasmodium vivax thioredoxin reductase, putative 0.0087 0.0177 0.1125
Loa Loa (eye worm) hypothetical protein 0.0109 0.0232 0.0488
Loa Loa (eye worm) Smad1 0.0034 0.0042 0.0084
Echinococcus multilocularis FTZ F1 alpha 0.0084 0.0169 0.0262
Entamoeba histolytica G protein alpha subunit, putative 0.0022 0.0011 0.0048
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0058 0.036
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0065 0.0121 0.0252
Schistosoma mansoni high-affinity choline transporter 0.0037 0.005 0.0109
Echinococcus multilocularis dna polymerase eta 0.0039 0.0054 0.0081
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0034 0.0041 0.0061
Brugia malayi Bromodomain containing protein 0.0127 0.0277 0.0589
Schistosoma mansoni smad1 5 8 and 0.0034 0.0042 0.0091
Brugia malayi Thioredoxin reductase 0.0087 0.0177 0.0376
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0032 0.0194
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0014 0.0073
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0425 0.1713
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0084 0.0169 0.036
Echinococcus granulosus dna polymerase kappa 0.0039 0.0054 0.0119
Loa Loa (eye worm) hypothetical protein 0.0044 0.0068 0.014
Brugia malayi MH2 domain containing protein 0.0502 0.123 0.2614
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.0209 0.1209
Leishmania major glycosyl hydrolase-like protein 0.0054 0.0093 0.021
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0134 0.0303
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0022 0.0011 0.0023
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0011 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0568 0.1398 0.8174
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0011 0.0019
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0067 0.042
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0017 0.0037
Entamoeba histolytica hypothetical protein 0.0691 0.1709 1
Echinococcus granulosus lysine specific demethylase 5A 0.0211 0.0491 0.1124
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0085
Leishmania major long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty acid thiokinase (long chain), putative 0.0023 0.0013 0.0024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0068 0.0151
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0037 0.005 0.0075
Brugia malayi chromobox protein homolog 3 0.0038 0.0052 0.011
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0134 0.0303
Echinococcus granulosus peregrin 0.0127 0.0277 0.0631
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0168 0.0382 0.0786
Leishmania major acetyl-CoA synthetase, putative 0.0163 0.0368 0.0853
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.0096 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Brugia malayi nuclear receptor RXR 0.004 0.0056 0.012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0033 0.0125
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0619 0.1528 0.1528
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0276 0.0629
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0216 0.049
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 0.0023 0.0013 0.0023
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0121 0.0261 0.1697
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0163 0.0368 0.0368
Echinococcus granulosus jumonji domain containing 1A 0.0055 0.0095 0.0212
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0357 0.1439
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0278 0.066 0.066
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0024 0.0017 0.0107
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0093 0.0366
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1732 0.435 1
Brugia malayi F/Y-rich N-terminus family protein 0.0071 0.0136 0.029
Brugia malayi MAP kinase sur-1 0.0158 0.0357 0.0759
Echinococcus multilocularis carboxylesterase 5A 0.007 0.0134 0.0206
Echinococcus granulosus PHD finger protein rhinoceros 0.0123 0.0268 0.061
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0126 0.0276 0.043
Mycobacterium leprae conserved hypothetical protein 0.0619 0.1528 0.3552
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.067 0.2712
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0032 0.0068
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0033 0.0125
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0134 0.0307
Loa Loa (eye worm) hypothetical protein 0.007 0.0134 0.0278
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0163 0.0368 0.0758
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0507 0.1243 0.2854
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.006 0.0131
Schistosoma mansoni FFA transport protein 0.1732 0.435 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0168 0.0382 0.0811
Brugia malayi RNA, U transporter 1 0.0332 0.0798 0.1696
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0021 0.0008 0.0008
Brugia malayi hypothetical protein 0.0044 0.0068 0.0145
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0022 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Echinococcus granulosus translational activator gcn1 0.0022 0.0011 0.002
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0038 0.0075
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0357 0.1439
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0014 0.0025
Mycobacterium ulcerans hypothetical protein 0.0163 0.0368 0.0758
Loa Loa (eye worm) hypothetical protein 0.0084 0.0169 0.0354
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0054 0.0093 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0056 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0084 0.0169 0.036
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0185
Loa Loa (eye worm) jmjC domain-containing protein 0.0055 0.0095 0.0196
Mycobacterium tuberculosis Probable oxidoreductase 0.0221 0.0517 0.0517
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0357 0.1439
Schistosoma mansoni jumonji/arid domain-containing protein 0.0211 0.0491 0.1124
Loa Loa (eye worm) glutaminase 0.0266 0.0631 0.1335
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0022 0.0011 0.0019
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0134 0.0863
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0034 0.0071
Trypanosoma brucei glucose transporter, putative 0.0032 0.0036 0.022
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0163 0.0368 0.2399
Echinococcus multilocularis neutral sphingomyelinase 0.0024 0.0017 0.0023
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0055 0.0095 0.0605
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0114 0.0216
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. 0.0023 0.0013 0.0013
Entamoeba histolytica HEAT repeat domain containing protein 0.0022 0.0011 0.0052
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0038 0.0055
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0095 0.0196 0.0784
Brugia malayi hypothetical protein 0.0023 0.0013 0.0027
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0014 0.0025
Leishmania major protein kinase, putative 0.0033 0.004 0.0086
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0163 0.0368 0.0848
Schistosoma mansoni smad1 5 8 and 0.0034 0.0042 0.0091
Echinococcus multilocularis Smad4 0.0034 0.0042 0.0062
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0051 0.0085 0.0085
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0023 0.0013 0.0067
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Schistosoma mansoni coup transcription factor 0.0084 0.0169 0.0383
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0324 0.0739
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0056 0.0085
Echinococcus multilocularis inhibitor of apoptosis protein 0.0053 0.009 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0036 0.0136
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.0574 0.0899
Schistosoma mansoni hypothetical protein 0.1233 0.3084 0.7089
Loa Loa (eye worm) oxidoreductase 0.0163 0.0368 0.0778
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0014 0.0025
Echinococcus granulosus RUN 0.0041 0.006 0.0132
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0059 0.0229
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0056 0.0085
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.004 0.0085
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.1398 0.5666
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0036 0.0077
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0186 0.0428 0.0884
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.0232 0.0527
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.1398 0.5666
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0054 0.0115
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0163 0.0368 0.2143
Echinococcus multilocularis AMP dependent ligase 0.0028 0.0026 0.0037
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0022 0.0011 0.0033
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0163 0.0368 0.0848
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0087 0.0177 0.0177
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0024 0.0017 0.0075
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0023 0.0013 0.0023
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative 0.0023 0.0013 0.0041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0032 0.0068
Giardia lamblia Long chain fatty acid CoA ligase 5 0.0023 0.0013 0.0073
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0163 0.0368 0.0758
Loa Loa (eye worm) nuclear factor I 0.0019 0.0003 0.0002
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0023 0.0013 0.0041
Schistosoma mansoni glucose transport protein 0.0103 0.0216 0.049
Schistosoma mansoni zinc finger protein 0.004 0.0056 0.0123
Brugia malayi jmjC domain containing protein 0.0055 0.0095 0.0202
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.002 0.0041
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0022 0.0011 0.0013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.1398 0.5666
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0185
Trichomonas vaginalis sucrase-isomaltase, putative 0.0145 0.0324 0.1305
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0013 0.0022
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0082 0.0183
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0145 0.0324 0.1305
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0013 0.0022
Mycobacterium tuberculosis Putative polyketide synthase Pks16 0.0023 0.0013 0.0013
Trypanosoma brucei glucose transporter, putative 0.0032 0.0036 0.022
Trichomonas vaginalis Phospholipase C precursor, putative 0.0024 0.0017 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0084 0.0169 0.036
Brugia malayi Carboxylesterase family protein 0.007 0.0134 0.0284
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0017 0.0037
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0014 0.0002
Trypanosoma brucei fatty acyl CoA synthetase 3 0.0023 0.0013 0.0067
Echinococcus multilocularis translational activator gcn1 0.0022 0.0011 0.0014
Trypanosoma cruzi mitochondrial protein 99, putative 0.0024 0.0017 0.0034
Entamoeba histolytica acyl-CoA synthetase, putative 0.0163 0.0368 0.2143
Echinococcus multilocularis smad 0.0034 0.0042 0.0062
Toxoplasma gondii LsmAD domain-containing protein 0.0109 0.0232 0.1504
Echinococcus granulosus pyruvate kinase 0.0034 0.0042 0.009
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0124 0.0279
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0013 0.006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0068 0.014
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0054 0.011
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0876 0.2178 0.4629
Onchocerca volvulus 0.0619 0.1528 0.6181
Echinococcus granulosus lysosomal alpha glucosidase 0.0654 0.1616 0.3712
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0038 0.0081
Schistosoma mansoni neutral sphingomyelinase 0.0024 0.0017 0.0034
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0013 0.0019
Echinococcus granulosus expressed protein 0.0022 0.0011 0.0019
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.004 0.0085
Echinococcus granulosus ecdysone induced protein 78C 0.0084 0.0169 0.0383
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0042 0.0062
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0158 0.0357 0.2323
Schistosoma mansoni protein kinase 0.0033 0.004 0.0085
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0084 0.0169 0.0646
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0065 0.0121 0.0273
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0038 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0033 0.0125
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0032 0.0047
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0068 0.0145
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0032 0.0194
Loa Loa (eye worm) jmjC domain-containing protein 0.0211 0.0491 0.1039
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0054 0.0338
Loa Loa (eye worm) latrophilin receptor protein 2 0.0277 0.0659 0.1395
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0031
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0022 0.0011 0.0019
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0023 0.0013 0.0023
Mycobacterium tuberculosis Probable exported protein 0.0024 0.0017 0.0017
Giardia lamblia Kinase, CMGC MAPK 0.0158 0.0357 0.2539
Brugia malayi hypothetical protein 0.0023 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0084 0.0169 0.0354
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0163 0.0368 0.0841
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0084 0.0169 0.036
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0042 0.0084
Schistosoma mansoni jumonji domain containing protein 0.0055 0.0095 0.0212
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0042 0.0258
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0038 0.023
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0017 0.0037
Leishmania major hypothetical protein, conserved 0.0055 0.0095 0.0215
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0054 0.0093 0.0366
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0055 0.0095 0.0212
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0042 0.0089
Mycobacterium leprae POSSIBLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE) 0.0023 0.0013 0.0019
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0011 0.0033
Trypanosoma brucei glucose transporter, putative 0.0032 0.0036 0.022
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0084 0.0169 0.0262
Schistosoma mansoni synaptojanin 0.0024 0.0017 0.0034
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0306 0.0707
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0084 0.0169 0.0354
Loa Loa (eye worm) hypothetical protein 0.0163 0.0368 0.0778
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0145 0.0324 0.1883
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0036 0.0078
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0022 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0084 0.0169 0.0354
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0121 0.0261 0.0595
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Echinococcus multilocularis acyl coenzyme A synthetase family 0.0023 0.0013 0.0016
Onchocerca volvulus 0.003 0.0031 0.0082
Trypanosoma brucei RNA editing exonuclease 2 0.0024 0.0017 0.0096
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0082 0.0173
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0163 0.0368 0.0368
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0014 0.0072
Schistosoma mansoni inositol transporter 0.0037 0.005 0.0109
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0006 0.0015
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0096
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Loa Loa (eye worm) acetylcholinesterase 1 0.007 0.0134 0.0278
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0022 0.0011 0.0019
Loa Loa (eye worm) sugar transporter 0.0103 0.0216 0.0453
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0042 0.016
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0036 0.0077
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0032 0.0173
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0024 0.0017 0.0059
Brugia malayi Cam kinase protein 1 0.0033 0.004 0.0084
Schistosoma mansoni cpg binding protein 0.0091 0.0188 0.0426
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0163 0.0368 0.0758
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0042 0.016
Schistosoma mansoni thyroid hormone receptor 0.0084 0.0169 0.0383
Brugia malayi PHD-finger family protein 0.0045 0.007 0.0149
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative 0.0023 0.0013 0.0041
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0054 0.012
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0036 0.0079
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.1398 0.5666
Brugia malayi jmjC domain containing protein 0.0055 0.0095 0.0202
Echinococcus multilocularis acetylcholinesterase 0.007 0.0134 0.0206
Brugia malayi nuclear hormone receptor family member odr-7 0.004 0.0056 0.012
Giardia lamblia Kinase, PLK 0.01 0.0209 0.1479
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.0163 0.0368 0.0853
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative 0.0023 0.0013 0.0041
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0163 0.0368 0.0758
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.02
Brugia malayi exodeoxyribonuclease III family protein 0.0121 0.0261 0.0556
Echinococcus multilocularis lysosomal alpha glucosidase 0.0654 0.1616 0.2541
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0037 0.005 0.0075
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0051 0.0085 0.0155
Plasmodium vivax acetyl-CoA synthetase, putative 0.0163 0.0368 0.2382
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.001
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.004 0.0058
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0022 0.0011 0.0058
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0114 0.0257
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.002 0.0112
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0054 0.0093 0.0334
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0163 0.0368 0.0368
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0042 0.0042
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0121 0.0261 0.1855
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0054 0.0094 0.0093
Onchocerca volvulus 0.005 0.0082 0.0288
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0022 0.0011 0.0019
Mycobacterium tuberculosis Probable dehydrogenase 0.0199 0.0461 0.0461
Brugia malayi hypothetical protein 0.007 0.0134 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0024 0.0137
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0049 0.0079 0.0498
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0036 0.0136
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.207 0.3256
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0169 0.0262
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0017 0.0037
Echinococcus granulosus Smad4 0.0034 0.0042 0.0091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0031
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0054 0.0093 0.0207
Echinococcus granulosus neutral alpha glucosidase AB 0.0145 0.0324 0.0739
Brugia malayi Importin beta-1 subunit 0.0117 0.0252 0.0535
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0056 0.0123
Trypanosoma brucei glucosidase, putative 0.0145 0.0324 0.2107
Leishmania major fatty acyl CoA syntetase 1, putative 0.0023 0.0013 0.0024
Schistosoma mansoni thyroid hormone receptor 0.0084 0.0169 0.0383
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0033 0.004 0.0244
Loa Loa (eye worm) hypothetical protein 0.007 0.0134 0.0278
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.004 0.0084
Echinococcus multilocularis importin subunit beta 1 0.0117 0.0252 0.0392
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0158 0.0357 0.0753
Mycobacterium leprae Probable polyketide synthase Pks1 0.0054 0.0094 0.0207
Brugia malayi Ets-domain containing protein 0.007 0.0134 0.0284
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0059 0.0229
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0017
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.1709 0.4293 1
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0014 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0056 0.0218
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0163 0.0368 0.0848
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.004 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0425 0.1713
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0158 0.0357 0.2323
Echinococcus multilocularis dnaJ subfamily B 0.1233 0.3084 0.4852
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0054 0.0054
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0024 0.0017 0.0085
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0032 0.0068
Echinococcus granulosus neutral sphingomyelinase 0.0024 0.0017 0.0034
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0282 0.067 0.1425
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0085 0.017 0.0264
Echinococcus granulosus histone lysine methyltransferase setb 0.0126 0.0276 0.0629
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 0.0023 0.0013 0.0023
Echinococcus multilocularis phd:f box containing protein 0.0055 0.0095 0.0145
Plasmodium vivax hypothetical protein, conserved 0.0123 0.0268 0.1722
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0084 0.0169 0.0383
Brugia malayi Flap endonuclease-1 0.0025 0.002 0.0042
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0114 0.0176
Plasmodium vivax hypothetical protein, conserved 0.0619 0.1528 1
Echinococcus granulosus long chain fatty acid coenzyme A ligase 4 0.0023 0.0013 0.0023
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 4 0.0023 0.0013 0.0016
Loa Loa (eye worm) steroid hormone receptor 0.0084 0.0169 0.0354
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0324 0.1305
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.0169 0.036
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0013 0.0046
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0042 0.009
Loa Loa (eye worm) jmjC domain-containing protein 0.0254 0.0601 0.1271
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.004 0.0085
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0038 0.0076
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0158 0.0357 0.0815
Trypanosoma brucei fatty acyl CoA syntetase 1 0.0023 0.0013 0.0067
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0034 0.0222
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Mycobacterium ulcerans polyketide synthase 0.0054 0.0094 0.0172
Brugia malayi Fli-1 protein 0.0213 0.0497 0.1056
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.017 1
Brugia malayi tailless protein 0.004 0.0056 0.012
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0158 0.0357 0.0826
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0216 0.0336
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0031
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0017 0.0031
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0168 0.0382 0.0381
Echinococcus granulosus JmjC domain containing protein 4 0.0055 0.0095 0.0212
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0017 0.0031
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.004 0.0056 0.0123
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.012 0.0259 0.0591
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0047 0.0102
Giardia lamblia Long chain fatty acid CoA ligase 5 0.0023 0.0013 0.0073
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0077 0.015 0.015
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0032 0.1231
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0024 0.0017 0.0107
Loa Loa (eye worm) hypothetical protein 0.0619 0.1528 0.3243
Leishmania major hypothetical protein, conserved 0.0619 0.1528 0.3555
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0188 0.0433 0.099
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0023 0.0013 0.0041
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0036 0.0078
Onchocerca volvulus 0.0163 0.0368 0.1457
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.002 0.0122
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Brugia malayi nuclear hormone receptor 0.004 0.0056 0.012
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0067 0.026
Brugia malayi Doublecortin family protein 0.0041 0.006 0.0127
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0024 0.0017 0.0034
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0221 0.0517 0.1195
Schistosoma mansoni Smad4 0.0034 0.0042 0.0091
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0024 0.0017 0.0059
Entamoeba histolytica Ran family GTPase 0.0065 0.0121 0.0694
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0122
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0096
Onchocerca volvulus 0.0041 0.006 0.02
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Giardia lamblia PHD finger protein 15 0.0123 0.0268 0.1901
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0023 0.0013 0.0013
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0036 0.0222
Brugia malayi AF-10 protein 0.004 0.0058 0.0122
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0067 0.0147
Loa Loa (eye worm) beta-lactamase 0.0619 0.1528 0.3243
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0084 0.0169 0.0354
Entamoeba histolytica hypothetical protein 0.0023 0.0013 0.006
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.002 0.0036
Mycobacterium ulcerans esterase/lipase LipP 0.0619 0.1528 0.3228
Leishmania major hypothetical protein, conserved 0.0023 0.0013 0.0024
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0028 0.0026 0.0028
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0013 0.0019
Plasmodium falciparum thioredoxin reductase 0.0087 0.0177 0.1616
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0042 0.0091
Echinococcus multilocularis pyruvate kinase 0.0034 0.0042 0.0062
Plasmodium falciparum flap endonuclease 1 0.0025 0.002 0.0131
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0017 0.0037
Toxoplasma gondii PHD-finger domain-containing protein 0.0123 0.0268 0.1739
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.01 0.0209 0.0325
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.067 0.2712
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0121 0.0261 0.053
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0017 0.0037
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0036 0.022
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0031
Trichomonas vaginalis importin beta-1, putative 0.0095 0.0196 0.0784
Trypanosoma brucei fatty acyl CoA synthetase, putative 0.0023 0.0013 0.0067
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0334 0.0709
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.02
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.004 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0022 0.0044
Trypanosoma brucei glucose transporter, putative 0.0032 0.0036 0.022
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0056 0.0123
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0042 0.009
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0054 0.0338
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0047 0.0288
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0221 0.0517 0.0517
Loa Loa (eye worm) hypothetical protein 0.0163 0.0368 0.0778
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0121 0.0261 0.0261
Mycobacterium tuberculosis Probable reductase 0.0199 0.0461 0.0461
Echinococcus multilocularis lysine specific demethylase 6a 0.0055 0.0095 0.0145
Trypanosoma brucei glucose transporter, putative 0.0032 0.0036 0.022
Echinococcus granulosus acyl coenzyme A synthetase family 0.0023 0.0013 0.0023
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0038 0.0081
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0065 0.0121 0.0257
Echinococcus granulosus traf and tnf receptor associated protein 0.0024 0.0017 0.0034
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0042 0.0258
Onchocerca volvulus 0.004 0.0056 0.0185
Brugia malayi Sodium:solute symporter family protein 0.0037 0.005 0.0106
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0085 0.017 0.1137
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0163 0.0368 0.0368
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0032 0.0068
Echinococcus granulosus smad 0.0034 0.0042 0.0091
Echinococcus granulosus sodium:glucose cotransporter 0.0037 0.005 0.0109
Brugia malayi hypothetical protein 0.0102 0.0215 0.0457
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Leishmania major DNA polymerase kappa, putative 0.0039 0.0054 0.012
Brugia malayi Pre-SET motif family protein 0.0869 0.2161 0.4592
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0221 0.0517 0.0517
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.004 0.0058 0.036
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.006 0.0373
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.002 0.0112
Echinococcus multilocularis neutral alpha glucosidase AB 0.0145 0.0324 0.0506
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0425 0.1713
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.004 0.015
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0051 0.0085 0.0085
Schistosoma mansoni DNA polymerase eta 0.0039 0.0054 0.0119
Treponema pallidum fructose-bisphosphate aldolase 0.0568 0.1398 1
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0168 0.0382 0.0786
Leishmania major pyruvate kinase 0.0034 0.0042 0.0092
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0052 0.0167
Onchocerca volvulus 0.0024 0.0017 0.0026
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0054 0.0094 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Toxoplasma gondii propionate-CoA ligase 0.0163 0.0368 0.2399
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0186 0.0428 0.0977
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.004 0.0222
Schistosoma mansoni smad 0.0034 0.0042 0.0091
Mycobacterium tuberculosis Probable hydrolase 0.0619 0.1528 0.1528
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0199 0.0461 0.1064
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0042 0.0091
Echinococcus granulosus dna polymerase eta 0.0039 0.0054 0.0119
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0024 0.0017 0.0059
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0619 0.1528 0.1528
Echinococcus multilocularis thyroid hormone receptor alpha 0.0084 0.0169 0.0262
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0186 0.0428 0.0909
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.004 0.0056 0.0084
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0022 0.0011 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0211 0.049 0.1041
Schistosoma mansoni importin beta-1 0.0117 0.0252 0.0573
Brugia malayi CCR4 0.0024 0.0017 0.0037
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0163 0.0368 0.0758
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0127 0.0265
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0033 0.0125
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0084 0.0169 0.0383
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0134 0.0207
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0017 0.0037
Brugia malayi GH02984p 0.0037 0.005 0.0106
Brugia malayi glutaminase DH11.1 0.0266 0.0631 0.134
Loa Loa (eye worm) hypothetical protein 0.0619 0.1528 0.3243
Schistosoma mansoni hypothetical protein 0.005 0.0082 0.0181
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0032 0.0194
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0084 0.0169 0.0383
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0084 0.0169 0.0383
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0324 0.0739
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 0.0023 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0023 0.0013 0.0023
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0047 0.0102
Plasmodium vivax hexose transporter 0.0103 0.0216 0.138
Schistosoma mansoni glucose transport protein 0.0103 0.0216 0.049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.1398 0.5666
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0037 0.005 0.0109
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0054 0.0054
Trypanosoma brucei acyl-CoA synthetase, putative 0.0023 0.0013 0.0067
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0024 0.0017 0.0096
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0163 0.0368 0.0368
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0085 0.017 0.1553
Echinococcus granulosus dnaJ subfamily B 0.1233 0.3084 0.7089
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0014 0.0017
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0168 0.0382 0.0879
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.0574 0.1313
Echinococcus granulosus carboxylesterase 5A 0.007 0.0134 0.0301
Giardia lamblia Long chain fatty acid CoA ligase 4 0.0023 0.0013 0.0073
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.004 0.0318
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0054 0.0119
Onchocerca volvulus 0.0084 0.0169 0.0646
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0051 0.0085 0.0188
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0054 0.0338
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0032 0.0069
Echinococcus multilocularis high affinity choline transporter 1 0.0037 0.005 0.0075
Entamoeba histolytica acyl-coA synthetase, putative 0.0163 0.0368 0.2143
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0042 0.0084
Plasmodium vivax transportin, putative 0.0022 0.0011 0.0037
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.0696 0.4546
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0084 0.0169 0.036
Schistosoma mansoni RAR-like nuclear receptor 0.0084 0.0169 0.0383
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0096
Trypanosoma cruzi hypothetical protein, conserved 0.0619 0.1528 0.3508
Echinococcus granulosus serine protein kinase ATM 0.0026 0.002 0.0041
Loa Loa (eye worm) G protein alpha subunit 3 0.0022 0.0011 0.0017
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0032 0.0173
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0022 0.0011 0.0023
Schistosoma mansoni hypothetical protein 0.0277 0.0659 0.1509
Brugia malayi nuclear receptor NHR-88 0.004 0.0056 0.012
Loa Loa (eye worm) nuclear receptor NHR-67 0.004 0.0056 0.0114
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0034 0.0181
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0186 0.0428 0.0884
Toxoplasma gondii FATC domain-containing protein 0.0026 0.002 0.0116
Leishmania major RNA-editing complex protein MP100, putative 0.0024 0.0017 0.0034
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.004 0.0056 0.0123
Leishmania major endonuclease/exonuclease protein-like protein 0.0024 0.0017 0.0034
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0024 0.0017 0.0034
Plasmodium vivax glutathione reductase, putative 0.0087 0.0177 0.1125
Brugia malayi beta-lactamase family protein 0.0619 0.1528 0.3246
Loa Loa (eye worm) CXXC zinc finger family protein 0.0087 0.0175 0.0367
Echinococcus multilocularis long chain fatty acid transport protein 4 0.1732 0.435 0.6845
Trypanosoma cruzi PAB1-binding protein , putative 0.0109 0.0232 0.0527
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0032 0.0249
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0085
Treponema pallidum exodeoxyribonuclease (exoA) 0.0121 0.0261 0.1795
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0024 0.0017 0.0034
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0022 0.0011 0.0013
Brugia malayi hypothetical protein 0.0691 0.1709 0.3633
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Loa Loa (eye worm) hypothetical protein 0.0163 0.0368 0.0778
Toxoplasma gondii HEAT repeat-containing protein 0.0022 0.0011 0.0058
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0186 0.0428 0.0977
Entamoeba histolytica Flap nuclease, putative 0.0025 0.002 0.01
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0619 0.1528 0.3243
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0042 0.0084
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0034 0.0071
Echinococcus multilocularis lysosomal alpha glucosidase 0.0654 0.1616 0.2541
Onchocerca volvulus 0.0619 0.1528 0.6181
Brugia malayi beta-lactamase family protein 0.0619 0.1528 0.3246
Mycobacterium ulcerans glutaminase 0.0266 0.0631 0.1316
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0032 0.0041
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0085 0.017 0.0386
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.004 0.0222
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0022 0.0011 0.0013
Schistosoma mansoni GTP-binding protein alpha subunit 0.0022 0.0011 0.0019
Loa Loa (eye worm) importin-beta domain-containing protein 0.0022 0.0011 0.0019
Schistosoma mansoni inhibitor of apoptosis protein 0.0053 0.009 0.02
Loa Loa (eye worm) hypothetical protein 0.0619 0.1528 0.3243
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0022 0.0011 0.0017
Echinococcus multilocularis acetylcholinesterase 0.007 0.0134 0.0206
Giardia lamblia Pyruvate kinase 0.0034 0.0042 0.0282
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Plasmodium falciparum thioredoxin reductase 0.003 0.0032 0.0249
Plasmodium falciparum mitogen-activated protein kinase 2 0.0167 0.0381 0.3538
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.004 0.0058
Echinococcus granulosus beta LACTamase domain containing family member 0.0619 0.1528 0.3508
Loa Loa (eye worm) carboxylesterase 0.007 0.0134 0.0278
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0357 0.0815
Schistosoma mansoni synaptojanin 0.0024 0.0017 0.0034
Echinococcus granulosus inhibitor of apoptosis protein 0.0053 0.009 0.02
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0034 0.0071
Toxoplasma gondii type I fatty acid synthase, putative 0.0077 0.0151 0.0972
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0036 0.0136
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.006 0.0108 0.0241
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0024 0.0017 0.0075
Brugia malayi glutathione reductase 0.0087 0.0177 0.0376
Trypanosoma cruzi fatty acyl CoA synthetase, putative 0.0023 0.0013 0.0023
Trypanosoma brucei fatty acyl CoA synthetase, putative 0.0023 0.0013 0.0067
Plasmodium falciparum protein kinase 7 0.0292 0.0695 0.6512
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0216 0.0336
Trypanosoma cruzi mitochondrial protein 99, putative 0.0024 0.0017 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0024 0.0085
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.002 0.0039
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Echinococcus granulosus General substrate transporter 0.0088 0.0179 0.0406
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0013 0.0067
Brugia malayi hypothetical protein 0.0109 0.0232 0.0493
Schistosoma mansoni survival motor neuron protein 0.005 0.0082 0.0181
Leishmania major acetyl-CoA synthetase, putative 0.0163 0.0368 0.0853
Schistosoma mansoni hypothetical protein 0.0691 0.1709 0.3926
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0084 0.0169 0.0383
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0163 0.0368 0.0848
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0016 0.0077
Echinococcus granulosus serine:threonine protein kinase PLK1 0.01 0.0209 0.0475
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0277 0.0659 0.1509
Schistosoma mansoni hypothetical protein 0.0049 0.0079 0.0177
Trypanosoma cruzi fatty acyl CoA syntetase 1, putative 0.0023 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0085 0.017 0.0357
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0425 0.1713
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0507 0.1243 0.1954
Mycobacterium ulcerans Type I modular polyketide synthase 0.0051 0.0085 0.0155
Echinococcus granulosus geminin 0.1542 0.3868 0.8892
Trichomonas vaginalis set domain proteins, putative 0.0989 0.2465 1
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.0216 0.1398
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.002 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Brugia malayi kap beta 3 protein 0.0022 0.0011 0.0024
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0059 0.013
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0158 0.0357 0.0826
Schistosoma mansoni inositol transporter 0.0037 0.005 0.0109
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0032 0.012
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.0696 0.1616
Leishmania major 4-coumarate:coa ligase-like protein 0.0163 0.0368 0.0853
Trichomonas vaginalis rotamase, putative 0.0033 0.0038 0.0145
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0158 0.0357 0.0815
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.004 0.0058
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0085
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0134 0.0772
Brugia malayi hypothetical protein 0.0041 0.006 0.0127
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0024 0.0017 0.0059
Mycobacterium tuberculosis Conserved protein 0.0619 0.1528 0.1528
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0093 0.0366
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Mycobacterium ulcerans polyketide synthase Pks13 0.0077 0.015 0.0292
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0024 0.0017 0.0023
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0017 0.0031
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0024 0.0017 0.0034
Trypanosoma brucei glucose transporter, putative 0.0032 0.0036 0.022
Loa Loa (eye worm) hypothetical protein 0.0102 0.0215 0.0452
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0056 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0209 0.0838
Brugia malayi Ets-domain containing protein 0.007 0.0134 0.0284
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0163 0.0368 0.0368
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0869 0.2161 0.4589
Loa Loa (eye worm) hypothetical protein 0.0045 0.007 0.0143
Trichomonas vaginalis penicillin-binding protein, putative 0.0619 0.1528 0.6193
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0054 0.0093 0.0207
Brugia malayi Nuclear hormone receptor E75 0.004 0.0056 0.012
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0042 0.0258
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0085
Echinococcus multilocularis beta LACTamase domain containing family member 0.0619 0.1528 0.2401
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0134 0.0302
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.006 0.0131
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0121 0.0261 0.168
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0216 0.049
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0017 0.0037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0032 0.0068
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0049 0.0079 0.0121
Echinococcus granulosus lysine specific demethylase 6a 0.0055 0.0095 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0005 0.001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0876 0.2178 0.4629
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Echinococcus multilocularis solute carrier family 5 0.0037 0.005 0.0075
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0011 0.0019
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0022 0.0011 0.0023
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.01 0.0209 0.0481
Schistosoma mansoni ap endonuclease 0.0121 0.0261 0.0595
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0023 0.0013 0.0041
Echinococcus granulosus high affinity choline transporter 1 0.0037 0.005 0.0109
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.002 0.0091
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0168 0.0382 0.0381
Trypanosoma brucei pantothenate kinase subunit, putative 0.0023 0.0013 0.0067
Echinococcus multilocularis traf and tnf receptor associated protein 0.0024 0.0017 0.0023
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.004 0.0056 0.0123
Brugia malayi hypothetical protein 0.0041 0.006 0.0127
Loa Loa (eye worm) nuclear receptor nhr-7B 0.004 0.0056 0.0114
Trypanosoma brucei Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5), putative 0.0023 0.0013 0.0067
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0277 0.0659 0.1509
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0032 0.0068
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0054 0.0209
Brugia malayi Disco-interacting protein 2 homolog 0.0023 0.0013 0.0027
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0038 0.008
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0023 0.0013 0.0023
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.005 0.0081 0.0081
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.006 0.0132
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0024 0.0017 0.0059
Echinococcus granulosus mitogen activated protein kinase 0.0158 0.0357 0.0815
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.0696 0.1595
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0691 0.1709 0.2687
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0199 0.0461 0.0461
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0005 0.0005
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0121 0.0261 0.055
Plasmodium falciparum importin beta, putative 0.0117 0.0252 0.2322
Trichomonas vaginalis D-aminoacylase, putative 0.0619 0.1528 0.6193
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.1398 0.5666
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.0276 0.043
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0199 0.0461 0.0461
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0024 0.0017 0.0059
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0056 0.0085
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0032 0.012
Brugia malayi MH2 domain containing protein 0.0034 0.0042 0.009
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0085 0.017 0.0386
Schistosoma mansoni cript-related 0.0024 0.0017 0.0034
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0013 0.0024
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0199 0.0461 0.0461
Loa Loa (eye worm) hypothetical protein 0.0037 0.005 0.0101
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0041 0.006 0.0129
Echinococcus multilocularis thioredoxin glutathione reductase 0.0088 0.0178 0.0277
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0163 0.0368 0.2399
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0016
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0014 0.0078
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.017 0.11
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0011 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0054 0.0119
Leishmania major fatty acyl CoA synthetase 2, putative 0.0023 0.0013 0.0024
Brugia malayi Probable ClpP-like protease 0.0085 0.017 0.0362
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Trypanosoma cruzi fatty acyl CoA synthetase, putative 0.0023 0.0013 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0568 0.1398 0.8174
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0121 0.0261 1
Brugia malayi hypothetical protein 0.0022 0.0011 0.0023
Brugia malayi Pre-SET motif family protein 0.0126 0.0276 0.0586
Toxoplasma gondii exonuclease III APE 0.0121 0.0261 0.1697
Echinococcus granulosus phd:f box containing protein 0.0055 0.0095 0.0212
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0042 0.0127
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0017 0.0031
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0114 0.0731
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 0.0023 0.0013 0.0016
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0041 0.006 0.0101
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0013 0.0027
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Echinococcus multilocularis PHD finger protein rhinoceros 0.0123 0.0268 0.0418
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0121 0.0261 0.0595
Echinococcus multilocularis JmjC domain containing protein 4 0.0055 0.0095 0.0145
Schistosoma mansoni ran 0.0065 0.0121 0.0273
Loa Loa (eye worm) hypothetical protein 0.0084 0.0169 0.0354
Plasmodium falciparum phd finger protein, putative 0.0123 0.0268 0.2474
Loa Loa (eye worm) hypothetical protein 0.003 0.0031 0.006
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.004 0.0242
Trypanosoma brucei glucose transporter, putative 0.0032 0.0036 0.022
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0071 0.0428
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0024 0.0017 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0084 0.0169 0.036
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0054 0.0094 0.0207
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0186 0.0428 0.0427
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0121 0.0261 0.1517
Mycobacterium ulcerans lipase LipD 0.0619 0.1528 0.3228
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.006 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0024 0.0017 0.0034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0507 0.1243 0.2854
Leishmania major pantothenate kinase subunit, putative 0.0047 0.0075 0.0168
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0026 0.0137
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0047 0.0101
Loa Loa (eye worm) histone methyltransferase 0.0031 0.0035 0.0069
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0053 0.009 0.0191
Leishmania major hypothetical protein, conserved 0.0022 0.0011 0.0021
Leishmania major DNA polymerase eta, putative 0.0039 0.0054 0.012
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0096
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0054 0.0119
Trichomonas vaginalis AMP dependent CoA ligase, putative 0.0023 0.0013 0.0041
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.004 0.0242
Schistosoma mansoni pyruvate kinase 0.0034 0.0042 0.009
Loa Loa (eye worm) hypothetical protein 0.0226 0.053 0.1121
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0024 0.0017 0.0034
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0024 0.0017 0.0031
Trypanosoma brucei fatty acyl CoA synthetase 4 0.0023 0.0013 0.0067
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0054 0.0209
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0023 0.0013 0.0019
Chlamydia trachomatis pyruvate kinase 0.0034 0.0042 0.1848
Toxoplasma gondii PHD-finger domain-containing protein 0.0123 0.0268 0.1739
Loa Loa (eye worm) hypothetical protein 0.0619 0.1528 0.3243
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0053 0.009 0.02
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.004 0.0242
Schistosoma mansoni hypothetical protein 0.1542 0.3868 0.8892
Brugia malayi CXXC zinc finger family protein 0.0087 0.0175 0.0372
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0084 0.0169 0.0262
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.0096 0.0096
Trypanosoma brucei glucose transporter 1E 0.0032 0.0036 0.022
Echinococcus granulosus chromobox protein 1 0.0068 0.0127 0.0287
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.067 0.2712
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.001 0.0031
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0038 0.0301
Leishmania major hypothetical protein, conserved 0.0024 0.0017 0.0034
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.004 0.0056 0.0084
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0174 0.0396 0.0836
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0023 0.0013 0.0013
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0056 0.0084
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0067 0.04
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0022 0.0011 0.0023
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0876 0.2178 0.4626
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0032 0.0068
Echinococcus granulosus expressed protein 0.0033 0.0038 0.0082
Schistosoma mansoni carbon catabolite repressor protein 0.0024 0.0017 0.0034
Schistosoma mansoni nuclear receptor 0.004 0.0056 0.0123
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0022 0.0011 0.0017
Brugia malayi nuclear receptor NHR-67 0.004 0.0056 0.012
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.0096 0.0148
Brugia malayi Heterochromatin protein 1 0.0068 0.0127 0.0271
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.002 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0084 0.0169 0.0354
Mycobacterium ulcerans hypothetical protein 0.0154 0.0345 0.0709
Onchocerca volvulus Glucosylceramidase homolog 0.0185 0.0425 0.1686
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0003 0.0006
Echinococcus granulosus nuclear receptor nhr 48 0.004 0.0056 0.0123
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0036 0.0077
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0028
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2521 0.6354 1
Toxoplasma gondii protein kinase, putative 0.0292 0.0695 0.4543
Trypanosoma brucei glycosyl hydrolase-like protein 0.0054 0.0093 0.059
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0163 0.0368 0.0853
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0022 0.003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Echinococcus granulosus AMP dependent ligase 0.0028 0.0026 0.0054
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0163 0.0368 0.0368
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0023 0.0013 0.0013
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0013 0.0024
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0023 0.0013 0.0013
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0121 0.0261 0.0603
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0054 0.0119
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0024 0.0017 0.0085
Toxoplasma gondii histone lysine methyltransferase SET1 0.0172 0.0393 0.2557
Mycobacterium tuberculosis Probable esterase LipL 0.0619 0.1528 0.1528
Loa Loa (eye worm) hypothetical protein 0.0277 0.0659 0.1395
Brugia malayi G-protein alpha subunit 0.0022 0.0011 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.1398 0.5666
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.006 0.0355
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0054 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0209 0.0838
Echinococcus granulosus microtubule associated protein 2 0.0833 0.207 0.4756
Onchocerca volvulus 0.0023 0.0013 0.0008
Schistosoma mansoni hypothetical protein 0.1542 0.3868 0.8892
Toxoplasma gondii HEAT repeat-containing protein 0.0022 0.0011 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0425 0.1713
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0121 0.0261 0.0408
Schistosoma mansoni jumonji domain containing protein 0.0377 0.0913 0.2095
Loa Loa (eye worm) transcription factor SMAD2 0.0502 0.123 0.261
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0055 0.0095 0.0212
Echinococcus multilocularis transportin 1 0.0022 0.0011 0.0014
Brugia malayi AMP-binding enzyme family protein 0.0163 0.0368 0.0783
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0054 0.0302
Brugia malayi jmjC domain containing protein 0.0055 0.0095 0.0202
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0145 0.0324 0.1883
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.002 0.004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0619 0.1528 0.3508
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0005 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0022 0.0011 0.0013
Brugia malayi AMP-binding enzyme family protein 0.0163 0.0368 0.0783
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0084 0.0169 0.036
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0324 0.1305
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0051 0.0085 0.0085
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0163 0.0368 0.2399
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0054 0.0119
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0033 0.0125
Brugia malayi hypothetical protein 0.0044 0.0068 0.0145
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0121 0.0261 0.2414
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0084 0.0169 0.0383
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0056 0.0385
Schistosoma mansoni hypothetical protein 0.0599 0.1475 0.3387
Brugia malayi Glycosyl hydrolases family 31 protein 0.0654 0.1616 0.3435
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0114 0.0216
Trichomonas vaginalis D-aminoacylase, putative 0.0619 0.1528 0.6193
Echinococcus granulosus importin 5 0.0022 0.0011 0.002
Mycobacterium leprae Probable lipase LipE 0.0619 0.1528 0.3552
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0042 0.0062
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0047 0.0267
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0032 0.0041
Schistosoma mansoni protein phosphatase 2C 0.0055 0.0095 0.0212
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.006 0.009
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0163 0.0368 0.0841
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Echinococcus multilocularis General substrate transporter 0.0088 0.0179 0.0278
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0023 0.0013 0.0067
Toxoplasma gondii ABC1 family protein 0.0619 0.1528 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0036 0.0078
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0196
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0038 0.0082
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0042 0.0127
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) 0.0023 0.0013 0.0013
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0013 0.0066
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0134 0.0285
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Echinococcus multilocularis expressed protein 0.0022 0.0011 0.0013
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Plasmodium falciparum ataxin-2 like protein, putative 0.0109 0.0232 0.2135
Schistosoma mansoni retinoic acid receptor RXR 0.0084 0.0169 0.0383
Loa Loa (eye worm) hypothetical protein 0.0876 0.2178 0.4626
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0134 0.0279
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0169 0.0383
Trichomonas vaginalis ap endonuclease, putative 0.0121 0.0261 0.1051
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0024 0.0017 0.0037
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0145 0.0324 0.1305
Loa Loa (eye worm) hypothetical protein 0.0163 0.0368 0.0778
Loa Loa (eye worm) hypothetical protein 0.0619 0.1528 0.3243
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0077 0.015 0.015
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0065 0.0121 0.0777
Loa Loa (eye worm) hypothetical protein 0.0044 0.0068 0.014
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.004 0.0058 0.036
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0029 0.0058
Echinococcus multilocularis mitogen activated protein kinase 3 0.0158 0.0357 0.0558
Entamoeba histolytica hypothetical protein 0.0023 0.0014 0.0064
Trichomonas vaginalis AMP dependent ligase, putative 0.0023 0.0013 0.0041
Echinococcus granulosus GPCR family 2 0.0277 0.0659 0.1509
Onchocerca volvulus Protein ultraspiracle homolog 0.0084 0.0169 0.0646
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0054 0.0119
Schistosoma mansoni chromobox protein 0.0068 0.0127 0.0287
Schistosoma mansoni ap endonuclease 0.0121 0.0261 0.0595
Echinococcus granulosus long chain fatty acid transport protein 4 0.1732 0.435 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0036 0.0198
Echinococcus multilocularis jumonji domain containing protein 0.0171 0.039 0.061
Leishmania major alpha glucosidase II subunit, putative 0.0145 0.0324 0.0749
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0168 0.0382 0.0786
Loa Loa (eye worm) hypothetical protein 0.0163 0.0368 0.0778
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0038 0.023
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0029 0.0155
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Onchocerca volvulus Serine\/threonine kinase homolog 0.01 0.0209 0.0808
Echinococcus granulosus synaptojanin 1 0.0024 0.0017 0.0034
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0507 0.1243 0.2642
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0024 0.0017 0.0096
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0003 0.0006
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Schistosoma mansoni hypothetical protein 0.0277 0.0659 0.1509
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0035 0.0074
Brugia malayi steroid hormone receptor 0.0084 0.0169 0.036
Treponema pallidum NADH oxidase 0.003 0.0032 0.014
Plasmodium falciparum DNase I-like protein, putative 0.0024 0.0017 0.0107
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0085 0.017 0.6026
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0093 0.0366
Schistosoma mansoni transcription factor LCR-F1 0.0691 0.1709 0.3926
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0022 0.0011 0.0019
Giardia lamblia Hypothetical protein 0.0023 0.0013 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0032 0.0068
Mycobacterium ulcerans thioesterase TesA 0.0043 0.0064 0.0109
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0209 0.0838
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0056 0.0123
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0017
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Echinococcus multilocularis disco interacting protein 2 0.0023 0.0013 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0168 0.0382 0.0786
Leishmania major 4-coumarate:coa ligase-like protein 0.0163 0.0368 0.0853
Loa Loa (eye worm) nuclear hormone receptor 0.004 0.0056 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0084 0.0169 0.036
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.0216 0.0336
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Schistosoma mansoni glutaminase 0.0266 0.0631 0.1444
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0013 0.0019
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.004 0.0318
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0024 0.0017 0.0096
Giardia lamblia Long chain fatty acid CoA ligase 5 0.0023 0.0013 0.0073
Giardia lamblia Long chain fatty acid CoA ligase, putative 0.0023 0.0013 0.0073
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0168 0.0382 0.0786
Echinococcus granulosus sodium:glucose cotransporter 2 0.0037 0.005 0.0109
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0041 0.006 0.0101
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0276 0.0629
Loa Loa (eye worm) hypothetical protein 0.0244 0.0574 0.1214
Echinococcus multilocularis peregrin 0.0127 0.0277 0.0432
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0029 0.0029 0.0029
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0034 0.0041 0.0085
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Loa Loa (eye worm) thioredoxin reductase 0.0087 0.0177 0.0371
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0017
Schistosoma mansoni nuclear receptor nhr-48 0.004 0.0056 0.0123
Brugia malayi jmjC domain containing protein 0.0211 0.0491 0.1044
Mycobacterium ulcerans Type I modular polyketide synthase 0.0051 0.0085 0.0155
Mycobacterium ulcerans polyketide synthase 0.0051 0.0085 0.0155
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0209 0.0838
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0357 0.1439
Treponema pallidum hypothetical protein 0.0024 0.0017 0.0032
Mycobacterium tuberculosis Conserved protein 0.0619 0.1528 0.1528
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0654 0.1616 0.3431
Onchocerca volvulus Fatty acid synthase homolog 0.0092 0.019 0.073
Brugia malayi ecdysteroid receptor 0.0084 0.0169 0.036
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0507 0.1243 0.1954
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0065 0.0121 0.0273
Trichomonas vaginalis hypothetical protein 0.0022 0.0011 0.0036
Schistosoma mansoni hypothetical protein 0.0277 0.0659 0.1509
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0024 0.0017 0.0096
Echinococcus multilocularis cpg binding protein 0.0091 0.0188 0.0291
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0097 0.0202 0.0429
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0114 0.0114
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0054 0.0338
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0277 0.0659 0.1033
Echinococcus multilocularis jumonji domain containing 1A 0.0055 0.0095 0.0145
Echinococcus multilocularis ecdysone induced protein 78C 0.0084 0.0169 0.0262
Brugia malayi MH1 domain containing protein 0.0019 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0084 0.0169 0.0354
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0014 0.0045
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0134 0.0303
Schistosoma mansoni glucose transport protein 0.0103 0.0216 0.049
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0037 0.005 0.0075
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0065 0.0121 0.0777
Trypanosoma cruzi AMP-binding enzyme, putative 0.0023 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0044 0.0068 0.014
Toxoplasma gondii PHD-finger domain-containing protein 0.004 0.0058 0.036
Onchocerca volvulus 0.0024 0.0017 0.0026
Brugia malayi Carboxylesterase family protein 0.007 0.0134 0.0284
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0168 0.0382 0.0381
Loa Loa (eye worm) hypothetical protein 0.0034 0.0042 0.0084
Echinococcus granulosus pyruvate kinase 0.0034 0.0042 0.009
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0211 0.049 0.1036
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.067 0.2712
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Schistosoma mansoni hypothetical protein 0.0041 0.006 0.0132
Brugia malayi Glycosyl hydrolases family 31 protein 0.0054 0.0093 0.0197
Plasmodium vivax importin-beta 2, putative 0.0117 0.0252 0.1616
Loa Loa (eye worm) fatty acid synthase 0.0051 0.0084 0.0172
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0022
Brugia malayi MH1 domain containing protein 0.0019 0.0003 0.0007
Loa Loa (eye worm) kap beta 3 protein 0.0022 0.0011 0.0019
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0068 0.0151
Schistosoma mansoni AMP dependent ligase 0.0023 0.0013 0.0023
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.006 0.0131
Loa Loa (eye worm) AMP-binding enzyme family protein 0.1872 0.4706 1
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0022 0.0011 0.0019
Schistosoma mansoni loxhd1 0.0041 0.006 0.0132
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 0.0023 0.0013 0.0016
Loa Loa (eye worm) PHD-finger family protein 0.0123 0.0268 0.0564
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0568 0.1398 0.5666
Echinococcus granulosus solute carrier family 5 0.0037 0.005 0.0109
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0068 0.014
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0032 0.0249
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0024 0.0017 0.0107
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0037 0.0049 0.0049
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0034 0.0071
Trichomonas vaginalis rotamase, putative 0.0032 0.0036 0.0137
Mycobacterium leprae Putative polyketide synthetase Pks16 0.0023 0.0013 0.0019
Mycobacterium ulcerans acetyl-CoA synthetase 0.0163 0.0368 0.0758
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0084 0.0169 0.036
Echinococcus granulosus snurportin 1 0.1246 0.3118 0.7167
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.002 0.0041
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0105
Echinococcus multilocularis lysine specific demethylase 5A 0.0206 0.0479 0.075
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0134 0.028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0084 0.0169 0.0354
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0024 0.0017 0.0034
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0024 0.0017 0.0085
Plasmodium vivax long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.0046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0084 0.0169 0.0383
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0169 0.0262
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0084 0.0169 0.036
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0209 0.0838
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0024 0.0017 0.0034
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0051 0.0085 0.0188
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0122
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0114 0.0257
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.004 0.0056 0.012
Trichomonas vaginalis alpha-glucosidase, putative 0.0145 0.0324 0.1305
Entamoeba histolytica acyl-CoA synthetase, putative 0.0168 0.0382 0.222
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0018
Brugia malayi hypothetical protein 0.0244 0.0574 0.1219
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 0.0023 0.0013 0.0023
Trichomonas vaginalis AMP dependent ligase, putative 0.0023 0.0013 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0209 0.0838
Schistosoma mansoni cpg binding protein 0.0091 0.0188 0.0426
Loa Loa (eye worm) hypothetical protein 0.006 0.0108 0.0224
Brugia malayi ecdysone receptor 0.004 0.0056 0.012
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0163 0.0368 0.0576
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0084 0.0169 0.0354
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0013 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0084 0.0169 0.0354
Echinococcus multilocularis mitogen activated protein kinase 0.0158 0.0357 0.0558
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0084 0.0169 0.0383
Trichomonas vaginalis AMP dependent ligase, putative 0.0023 0.0013 0.0041
Brugia malayi latrophilin 2 splice variant baaae 0.0599 0.1475 0.3135
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0306 0.0698
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0024 0.0017 0.0023
Onchocerca volvulus 0.0053 0.009 0.0321
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0038 0.0081
Brugia malayi Glycosyl hydrolases family 31 protein 0.0145 0.0324 0.0688
Brugia malayi nuclear hormone receptor family member nhr-6 0.004 0.0056 0.012
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0209 0.0838
Loa Loa (eye worm) hypothetical protein 0.0117 0.0252 0.053
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0024 0.0017 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0085 0.0336
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0022 0.0011 0.0017
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Brugia malayi Sugar transporter family protein 0.0103 0.0216 0.0459
Loa Loa (eye worm) jmjC domain-containing protein 0.0055 0.0095 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0066
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0047 0.0075 0.0166
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0013 0.0027
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0056 0.0125
Schistosoma mansoni GTP-binding protein alpha subunit 0.0022 0.0011 0.0019
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0024 0.0017 0.0034
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0054 0.0115
Brugia malayi hypothetical protein 0.004 0.0056 0.012
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0127 0.0506
Brugia malayi AMP-binding enzyme family protein 0.0163 0.0368 0.0783
Mycobacterium ulcerans acyl-CoA synthetase 0.0163 0.0368 0.0758
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0024 0.0017 0.0107
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0163 0.0368 0.0841
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0022 0.0011 0.0019
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.004 0.0222
Onchocerca volvulus 0.0137 0.0304 0.1195
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0216 0.0866
Brugia malayi MH1 domain containing protein 0.0034 0.0042 0.009
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0054 0.0119
Plasmodium vivax ATP-dependent acyl-CoA synthetase, putative 0.0023 0.0013 0.0046
Echinococcus granulosus GTP binding nuclear protein Ran 0.0065 0.0121 0.0273
Leishmania major pyruvate kinase 0.0034 0.0042 0.0092
Loa Loa (eye worm) hypothetical protein 0.0109 0.0231 0.0486
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0002
Plasmodium vivax long-chain fatty acid CoA ligase, putative 0.0023 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0023
Trypanosoma cruzi trypanothione reductase, putative 0.0087 0.0177 0.0401
Schistosoma mansoni cpg binding protein 0.0087 0.0175 0.0397
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0013 0.006
Schistosoma mansoni phd/f-box containing protein 0.0055 0.0095 0.0212
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0114
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0032 0.0069
Onchocerca volvulus Bile acid receptor homolog 0.0084 0.0169 0.0646
Trypanosoma cruzi fatty acyl CoA syntetase 1, putative 0.0023 0.0013 0.0023
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.017 0.0336
Plasmodium falciparum acyl-CoA synthetase 0.0023 0.0013 0.0066
Brugia malayi Nuclear hormone receptor E75 0.004 0.0056 0.012
Echinococcus multilocularis synaptojanin 1 0.0024 0.0017 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0024 0.0137
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0067 0.042
Trypanosoma cruzi hexose transporter 0.0032 0.0036 0.0077
Schistosoma mansoni hypothetical protein 0.0277 0.0659 0.1509
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0056 0.0123
Entamoeba histolytica hypothetical protein 0.0691 0.1709 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0169 0.0383
Schistosoma mansoni alpha-glucosidase 0.0563 0.1385 0.318
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0022 0.0011 0.0033
Schistosoma mansoni hypothetical protein 0.0023 0.0013 0.0023
Mycobacterium ulcerans hypothetical protein 0.0619 0.1528 0.3228
Plasmodium falciparum hexose transporter 0.0103 0.0216 0.1982
Plasmodium falciparum transportin 0.0022 0.0011 0.0053
Brugia malayi jmjC domain containing protein 0.046 0.1124 0.2388
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0163 0.0368 0.0368
Leishmania major glucose transporter, lmgt2 0.0032 0.0036 0.0078
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0145 0.0324 0.2107
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0043 0.0064 0.0138
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0023 0.0013 0.0023
Toxoplasma gondii hypothetical protein 0.0047 0.0075 0.0474
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0033 0.0125
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0055
Mycobacterium tuberculosis Probable thioesterase TesA 0.0043 0.0064 0.0064
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0011 0.0033
Echinococcus granulosus flap endonuclease 1 0.0025 0.002 0.0039
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0056 0.0185
Trichomonas vaginalis ap endonuclease, putative 0.0121 0.0261 0.1051
Onchocerca volvulus 0.0041 0.006 0.02
Echinococcus granulosus mixed lineage leukemia protein mll 0.0026 0.0022 0.0044
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.014 0.0311 0.0311
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0334 0.0762
Giardia lamblia Inositol 5-phosphatase 4 0.0024 0.0017 0.0105
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0277 0.0659 0.1033
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0084 0.0169 0.036
Trypanosoma brucei unspecified product 0.0039 0.0054 0.0338
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0057 0.0487
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0023 0.0013 0.0041
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0277 0.0659 0.14
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0024 0.0137
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0115 0.0248 0.0564
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0054 0.0338
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0163 0.0368 0.0783
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0011 0.002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0199 0.0461 0.0461
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0121 0.0261 0.0595
Plasmodium vivax SET domain protein, putative 0.0126 0.0276 0.1775
Entamoeba histolytica hypothetical protein 0.0095 0.0196 0.1131
Schistosoma mansoni rab6-interacting 0.0041 0.006 0.0132
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0032 0.0068
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0209 0.0475
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0026 0.0021 0.0119
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0196
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0034 0.0126
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0216 0.0336
Onchocerca volvulus 0.0378 0.0916 0.3688
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.0696 0.1595
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0024 0.0017 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0054 0.0093 0.0366
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0042 0.0084
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0016 0.0028

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1.7783 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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