Detailed information for compound 1097379

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 254.284 | Formula: C15H14N2O2
  • H donors: 3 H acceptors: 2 LogP: 2.62 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccccc1C1NN=C(C1)c1ccccc1O
  • InChi: 1S/C15H14N2O2/c18-14-7-3-1-5-10(14)12-9-13(17-16-12)11-6-2-4-8-15(11)19/h1-8,12,16,18-19H,9H2
  • InChiKey: INFGLUYMRONKHY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Monoamine oxidase B Starlite/ChEMBL References
Rattus norvegicus Monoamine oxidase A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum hypothetical protein Monoamine oxidase B   520 aa 539 aa 22.3 %
Dictyostelium discoideum hypothetical protein Monoamine oxidase B   520 aa 531 aa 23.2 %
Onchocerca volvulus Mitochondrial fission process protein 1 homolog Monoamine oxidase B   520 aa 469 aa 22.0 %
Dictyostelium discoideum amine oxidase Monoamine oxidase B   520 aa 489 aa 29.0 %
Brugia malayi amine oxidase, flavin-containing family protein Monoamine oxidase B   520 aa 479 aa 21.7 %
Dictyostelium discoideum hypothetical protein Monoamine oxidase B   520 aa 538 aa 21.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0092 0.0232
Brugia malayi glutaminase DH11.1 0.0238 0.3164 0.4641
Echinococcus multilocularis carboxylesterase 5A 0.0046 0.047 0.0502
Echinococcus multilocularis Tubulin beta 2C chain 0.0284 0.3812 0.4214
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.006 0.0047
Schistosoma mansoni adenoreceptor 0.0061 0.0668 0.0835
Trypanosoma brucei beta tubulin 0.0284 0.3812 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0127 0.1601 0.2336
Loa Loa (eye worm) hypothetical protein 0.0443 0.6048 0.6041
Mycobacterium ulcerans lipase LipD 0.0082 0.0972 0.0929
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.006 0.0042
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0082 0.0972 0.0929
Echinococcus multilocularis tubulin alpha 1C chain 0.021 0.2767 0.3054
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0039 0.0358 0.0437
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0614 0.1609
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0127 0.1601 0.1758
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.0936 0.118
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0061 0.0668 0.0722
Echinococcus granulosus peptide allatostatin:somatostatin 0.0061 0.0668 0.0722
Echinococcus granulosus voltage gated potassium channel 0.0039 0.0358 0.0378
Echinococcus granulosus neuropeptide s receptor 0.0061 0.0668 0.0722
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0092 0.0241
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0076 0.0888 0.0872
Brugia malayi hypothetical protein 0.0062 0.0681 0.0979
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0014 0.0018 0.0047
Schistosoma mansoni sodium/chloride dependent transporter 0.008 0.0936 0.118
Echinococcus granulosus allatostatin A receptor 0.0061 0.0668 0.0722
Echinococcus multilocularis serotonin receptor 0.0204 0.2693 0.2971
Plasmodium falciparum tubulin delta chain, putative 0.0066 0.0743 0.1911
Echinococcus multilocularis tubulin alpha 1C chain 0.021 0.2767 0.3054
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0061 0.0668 0.0844
Echinococcus granulosus neuropeptide FF receptor 2 0.0061 0.0668 0.0722
Chlamydia trachomatis dihydrofolate reductase 0.0043 0.0426 0.4201
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.0067 0.0753 0.0736
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0092 0.0053
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0668 0.0722
Brugia malayi cytochrome P450 0.0035 0.0305 0.0424
Brugia malayi G protein-coupled receptor F59B2.13 0.0061 0.0668 0.0959
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0358 0.0896
Loa Loa (eye worm) tubulin gamma chain 0.0152 0.1951 0.1937
Loa Loa (eye worm) hypothetical protein 0.0017 0.006 0.0042
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0127 0.1601 0.2033
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0127 0.1601 0.1758
Trypanosoma cruzi epsilon tubulin, putative 0.0152 0.1951 0.5118
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0469 0.642 0.9444
Echinococcus multilocularis beta tubulin 0.0284 0.3812 0.4214
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0039 0.0358 0.0501
Leishmania major beta tubulin 0.0284 0.3812 0.483
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0092 0.0241
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0504 0.6908 0.7652
Schistosoma mansoni hypothetical protein 0.0017 0.006 0.0054
Loa Loa (eye worm) BEN-1 protein 0.0284 0.3812 0.3801
Brugia malayi Pre-SET motif family protein 0.0037 0.0338 0.0473
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0042 0.04 0.0425
Leishmania major cytochrome p450-like protein 0.0072 0.0832 0.1054
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0014 0.0018 0.0023
Loa Loa (eye worm) ACC-1 protein 0.0127 0.1601 0.1586
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0127 0.1601 0.1758
Echinococcus granulosus hyperpolarization activated cyclic 0.0042 0.04 0.0425
Mycobacterium tuberculosis Probable oxidoreductase 0.0144 0.1839 0.1961
Echinococcus granulosus TRP transient receptor potential channel 0.0039 0.0358 0.0378
Giardia lamblia Gamma tubulin 0.0152 0.1951 0.5096
Echinococcus granulosus transient receptor potential gamma protein 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Leishmania major beta tubulin 0.0284 0.3812 0.483
Toxoplasma gondii cytochrome p450 superfamily protein 0.0035 0.0305 0.0757
Mycobacterium ulcerans thymidylate synthase 0.0106 0.1313 0.1275
Schistosoma mansoni tubulin subunit beta 0.0284 0.3812 0.4872
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0062 0.0681 0.0979
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0062 0.0681 0.0979
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0123 0.0311
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0035 0.0305 0.0253
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0017 0.0053 0.014
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.0023 0.0138 0.012
Loa Loa (eye worm) hypothetical protein 0.0204 0.2693 0.268
Echinococcus granulosus Tubulin alpha 1 chain 0.021 0.2767 0.3054
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0127 0.1601 0.1758
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0035 0.0305 0.0253
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0062 0.0681 0.0737
Loa Loa (eye worm) tubulin alpha 2 0.0144 0.184 0.1825
Plasmodium falciparum thioredoxin reductase 0.002 0.0092 0.0195
Echinococcus granulosus thymidylate synthase 0.0106 0.1313 0.1438
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0119 0.0267
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0043 0.0426 0.0418
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0082 0.0972 0.1014
Entamoeba histolytica tubulin family protein 0.0284 0.3812 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0044 0.0437 0.0466
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus multilocularis sodium channel protein 0.0574 0.7893 0.8746
Echinococcus granulosus hyperpolarization activated cyclic 0.0042 0.04 0.0425
Trichomonas vaginalis tubulin, putative 0.0284 0.3812 0.9616
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0014 0.0018 0.0023
Echinococcus multilocularis musashi 0.0067 0.0753 0.0816
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0668 0.0652
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Loa Loa (eye worm) hypothetical protein 0.0068 0.0766 0.075
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0242 0.3219 0.3555
Echinococcus multilocularis voltage gated potassium channel 0.0044 0.043 0.0458
Schistosoma mansoni hypothetical protein 0.0061 0.0668 0.0835
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.015 0.1924 0.5046
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0174 0.2259 0.2489
Loa Loa (eye worm) tubulin alpha 2 0.0144 0.184 0.1825
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Echinococcus granulosus potassium voltage gated channel protein 0.0039 0.0358 0.0378
Trichomonas vaginalis set domain proteins, putative 0.0295 0.3964 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0284 0.3812 0.4214
Plasmodium falciparum glutathione reductase 0.002 0.0092 0.0195
Schistosoma mansoni alpha tubulin 0.021 0.2767 0.3531
Schistosoma mansoni hypothetical protein 0.0017 0.006 0.0054
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0082 0.0972 0.1407
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0039 0.0358 0.0501
Echinococcus granulosus potassium voltage gated channel protein 0.0039 0.0358 0.0378
Echinococcus granulosus uncharacterized sodium dependent transporter 0.008 0.0936 0.102
Echinococcus granulosus tubulin alpha chain 0.021 0.2767 0.3054
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0035 0.0305 0.0253
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0138 0.0361
Echinococcus multilocularis transient receptor potential cation channel 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0039 0.0358 0.0437
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Brugia malayi tubulin alpha-2 chain 0.021 0.2767 0.4056
Mycobacterium tuberculosis Probable dehydrogenase 0.0129 0.1636 0.1739
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0032 0.0268 0.0278
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0053 0.0135
Leishmania major UDP-galactopyranose mutase 0.0051 0.0526 0.0667
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus multilocularis transient receptor potential cation channel 0.0039 0.0358 0.0378
Echinococcus multilocularis tubulin alpha chain 0.021 0.2767 0.3054
Onchocerca volvulus 0.0061 0.0668 0.0844
Brugia malayi Tachykinin-like peptides receptor 99D 0.0061 0.0668 0.0959
Loa Loa (eye worm) carboxylesterase 0.0046 0.047 0.0453
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0035 0.0305 0.0253
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0668 0.0722
Echinococcus granulosus biogenic amine 5HT receptor 0.0204 0.2693 0.2971
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0061 0.0668 0.0722
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0534 0.1347
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0574 0.7893 0.8746
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0061 0.0668 0.0959
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0014 0.0019 0.0001
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0127 0.1601 0.2336
Loa Loa (eye worm) hypothetical protein 0.0065 0.0735 0.0718
Echinococcus multilocularis transient receptor potential cation channel 0.0039 0.0358 0.0378
Loa Loa (eye worm) cytochrome P450 family protein 0.0072 0.0832 0.0815
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0534 0.136
Giardia lamblia Alpha-tubulin 0.021 0.2767 0.7246
Schistosoma mansoni ap endonuclease 0.0024 0.0157 0.0179
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Echinococcus granulosus beta tubulin 0.0284 0.3812 0.4214
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Leishmania major beta tubulin 0.0284 0.3812 0.483
Echinococcus multilocularis lysosomal alpha glucosidase 0.0076 0.0888 0.0966
Echinococcus multilocularis short transient receptor potential channel 6 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Trichomonas vaginalis glucosylceramidase, putative 0.016 0.2074 0.5232
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) glutathione reductase 0.0057 0.0614 0.0597
Trichomonas vaginalis tubulin gamma chain, putative 0.0152 0.1951 0.4922
Echinococcus granulosus 7TM GPCR rhodopsin 0.0061 0.0668 0.0722
Schistosoma mansoni hypothetical protein 0.0039 0.0358 0.0437
Loa Loa (eye worm) norepinephrine transporter 0.0469 0.642 0.6414
Echinococcus multilocularis neutral alpha glucosidase AB 0.0017 0.0053 0.004
Brugia malayi Melatonin receptor type 1A 0.0061 0.0668 0.0959
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0127 0.1601 0.1586
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0338 0.0356
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0051 0.0526 0.0653
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0035 0.0305 0.0253
Echinococcus granulosus sex peptide receptor 0.0061 0.0668 0.0722
Schistosoma mansoni intermediate filament proteins 0.0067 0.0753 0.0944
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0024 0.0157 0.0413
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0086 0.1024 0.2583
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0035 0.0305 0.0253
Schistosoma mansoni transcription factor LCR-F1 0.0021 0.0107 0.0115
Loa Loa (eye worm) hypothetical protein 0.0046 0.047 0.0453
Echinococcus multilocularis acetylcholinesterase 0.0046 0.047 0.0502
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.047 0.058
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.0936 0.118
Brugia malayi Tubulin alpha chain 0.021 0.2767 0.4056
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0051 0.0526 0.134
Echinococcus granulosus tubulin subunit TubB 0.021 0.2767 0.3054
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.008 0.0936 0.118
Echinococcus granulosus sodium and chloride dependent glycine 0.008 0.0936 0.102
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0689 0.0862
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0127 0.1601 0.1586
Onchocerca volvulus 0.0096 0.1163 0.1632
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0035 0.0305 0.0253
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Echinococcus granulosus single minded 2 0.0025 0.0174 0.0173
Echinococcus granulosus cytochrome P450 2K1 0.0035 0.0305 0.0319
Schistosoma mansoni sodium-dependent amino acid transporter 0.008 0.0936 0.118
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0082 0.0972 0.1225
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Trypanosoma brucei epsilon tubulin 0.0152 0.1951 0.5118
Echinococcus multilocularis tumor protein p63 0.0654 0.9022 1
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0039 0.0358 0.0501
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0138 0.0177
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0668 0.0722
Echinococcus multilocularis conserved hypothetical protein 0.0039 0.0358 0.0378
Brugia malayi GnHR receptor homolog 0.0061 0.0668 0.0959
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0138 0.0083
Schistosoma mansoni sodium/chloride dependent transporter 0.008 0.0939 0.1182
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Brugia malayi cation channel family protein 0.0039 0.0358 0.0501
Schistosoma mansoni alpha-1 adrenergic receptor 0.0061 0.0668 0.0835
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.0936 0.2421
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0526 0.1075
Entamoeba histolytica tubulin alpha chain, putative 0.021 0.2767 0.7259
Brugia malayi putative neuropeptide receptor NPR1 0.0061 0.0668 0.0959
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0035 0.0305 0.0286
Onchocerca volvulus 0.0179 0.2338 0.3502
Loa Loa (eye worm) hypothetical protein 0.0051 0.0526 0.051
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0534 0.0573
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0735 0.1058
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0127 0.1601 0.2336
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0039
Loa Loa (eye worm) glutaminase 2 0.0238 0.3164 0.3152
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0051 0.0526 0.134
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Schistosoma mansoni amine oxidase 0.0051 0.0526 0.0653
Loa Loa (eye worm) hypothetical protein 0.008 0.0936 0.092
Echinococcus granulosus acetylcholinesterase 0.0046 0.047 0.0502
Leishmania major hypothetical protein, conserved 0.0065 0.073 0.0924
Trypanosoma cruzi tubulin gamma chain 0.0152 0.1951 0.5118
Echinococcus multilocularis beta tubulin 0.0284 0.3812 0.4214
Trypanosoma brucei polo-like protein kinase 0.0044 0.0437 0.1147
Brugia malayi larval opioid receptor 0.0061 0.0668 0.0959
Echinococcus granulosus tubulin alpha chain 0.021 0.2767 0.3054
Echinococcus granulosus Tubulin beta 2C chain 0.0284 0.3812 0.4214
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0305 0.0801
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.006 0.0047
Schistosoma mansoni amine GPCR 0.0061 0.0668 0.0835
Schistosoma mansoni tubulin subunit beta 0.0284 0.3812 0.4872
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0092 0.0241
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0127 0.1601 0.1758
Trypanosoma brucei epsilon tubulin 0.0152 0.1951 0.5118
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0127 0.1601 0.1758
Loa Loa (eye worm) hypothetical protein 0.0469 0.642 0.6414
Echinococcus granulosus alpha 1A adrenergic receptor 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Schistosoma mansoni tubulin subunit beta 0.0284 0.3812 0.4872
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0039 0.0358 0.0378
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0127 0.1601 0.1586
Schistosoma mansoni voltage-gated ion channel 0.0039 0.0358 0.0437
Trichomonas vaginalis tubulin beta chain, putative 0.021 0.2767 0.6981
Brugia malayi hypothetical protein 0.0021 0.0107 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0437 0.1103
Schistosoma mansoni opsin-like receptor 0.0061 0.0668 0.0835
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0035 0.0305 0.0286
Schistosoma mansoni vesicular amine transporter 0.0039 0.0358 0.0437
Echinococcus granulosus transient receptor potential cation channel 0.0039 0.0358 0.0378
Onchocerca volvulus Glucosylceramidase homolog 0.0105 0.1297 0.1846
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0062 0.0681 0.0737
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0129 0.1636 0.1739
Trichomonas vaginalis glucosylceramidase, putative 0.016 0.2074 0.5232
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0061 0.0668 0.0722
Brugia malayi indoleamine 2,3-dioxygenase 0.0242 0.3219 0.4722
Onchocerca volvulus 0.0469 0.642 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0024 0.0157 0.0413
Echinococcus multilocularis acetylcholinesterase 0.0046 0.047 0.0502
Trypanosoma brucei tubulin gamma chain 0.0152 0.1951 0.5118
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Schistosoma mansoni biogenic amine receptor 0.0061 0.0668 0.0835
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0668 0.0835
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0024 0.0157 0.0102
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0668 0.0835
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0014 0.0018 0.0047
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.04 0.0491
Loa Loa (eye worm) cytochrome P450 family protein 0.0105 0.1297 0.1281
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0092 0.0116
Onchocerca volvulus 0.0062 0.0681 0.0865
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0127 0.1601 0.2033
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0039 0.0358 0.0938
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0024 0.0157 0.0295
Mycobacterium ulcerans esterase/lipase LipP 0.0082 0.0972 0.0929
Echinococcus granulosus shaker cognate 0.0039 0.0358 0.0378
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0092 0.0195
Echinococcus granulosus tachykinin peptides receptor 99D 0.0061 0.0668 0.0722
Echinococcus multilocularis transient receptor potential cation channel 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Schistosoma mansoni tubulin subunit beta 0.0066 0.0743 0.0931
Brugia malayi Pip kinase protein 2 0.0179 0.2338 0.3422
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0039 0.0358 0.0437
Brugia malayi beta-lactamase 0.0082 0.0972 0.1407
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0035 0.0305 0.0286
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0035 0.0305 0.0286
Loa Loa (eye worm) voltage-dependent calcium channel 0.0039 0.0358 0.0341
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Plasmodium vivax tubulin alpha chain, putative 0.021 0.2767 0.581
Echinococcus multilocularis tubulin alpha chain 0.021 0.2767 0.3054
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0035 0.0305 0.0286
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0039 0.0358 0.0437
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0053 0.0135
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0668 0.0835
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0021 0.0107 0.0099
Loa Loa (eye worm) hypothetical protein 0.008 0.0936 0.092
Plasmodium vivax amine transporter, putative 0.008 0.0936 0.1941
Onchocerca volvulus 0.0082 0.0972 0.1327
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Echinococcus multilocularis G protein coupled receptor 139 0.0061 0.0668 0.0722
Echinococcus multilocularis tubulin epsilon chain 0.0152 0.1951 0.2147
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.015 0.1924 0.5023
Trypanosoma cruzi PAB1-binding protein , putative 0.0065 0.073 0.1914
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0028 0.0209 0.0528
Brugia malayi hypothetical protein 0.008 0.0936 0.1355
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.008 0.0936 0.102
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0735 0.1058
Trypanosoma brucei zeta tubulin, putative 0.0066 0.0743 0.1948
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0039
Loa Loa (eye worm) LGC-31 protein 0.0127 0.1601 0.1586
Onchocerca volvulus 0.0082 0.0972 0.1327
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0437 0.1103
Loa Loa (eye worm) hypothetical protein 0.0144 0.184 0.1825
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.006 0.0047
Echinococcus multilocularis Tubulin beta 2C chain 0.0284 0.3812 0.4214
Trypanosoma brucei alpha tubulin, putative 0.0086 0.1024 0.2686
Loa Loa (eye worm) hypothetical protein 0.0469 0.642 0.6414
Schistosoma mansoni hypothetical protein 0.0029 0.0225 0.0267
Echinococcus granulosus tubulin alpha 3 chain 0.021 0.2767 0.3054
Echinococcus multilocularis 0.0035 0.0305 0.0319
Treponema pallidum cell division protein FtsZ 0.0066 0.0743 0.1028
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0092 0.0036
Echinococcus multilocularis G-protein coupled receptor, putative 0.0061 0.0668 0.0722
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.043 0.0529
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0035 0.0305 0.0286
Brugia malayi excitatory GABA receptor EXP-1A 0.0127 0.1601 0.2336
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0044 0.0437 0.042
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0035 0.0305 0.0801
Echinococcus granulosus transient receptor potential cation channel 0.0039 0.0358 0.0378
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0039 0.0358 0.0437
Schistosoma mansoni amine GPCR 0.0061 0.0668 0.0835
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0035 0.0305 0.0286
Echinococcus multilocularis lamin 0.0067 0.0753 0.0816
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0668 0.0652
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0039 0.0358 0.0437
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0534 0.136
Schistosoma mansoni transient receptor potential channel 0.0039 0.0358 0.0437
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Loa Loa (eye worm) glutaminase 0.0238 0.3164 0.3152
Loa Loa (eye worm) hypothetical protein 0.0082 0.0972 0.0955
Trypanosoma cruzi UDP-galactopyranose mutase 0.0051 0.0526 0.1381
Loa Loa (eye worm) hypothetical protein 0.0051 0.0526 0.051
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0092 0.0241
Echinococcus multilocularis serotonin receptor 0.0204 0.2693 0.2971
Loa Loa (eye worm) hypothetical protein 0.0061 0.0669 0.0652
Schistosoma mansoni 60S ribosomal protein L21 0.0041 0.0387 0.0475
Trichomonas vaginalis glucosylceramidase, putative 0.0105 0.1297 0.3273
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0062 0.0681 0.0979
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0138 0.0103
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0668 0.0722
Schistosoma mansoni nAChR subunit 0.0127 0.1601 0.2033
Schistosoma mansoni alpha-glucosidase 0.0066 0.0739 0.0926
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0668 0.0835
Trichomonas vaginalis glucosylceramidase, putative 0.0105 0.1297 0.3273
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0061 0.0668 0.0835
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0044 0.0437 0.0466
Echinococcus multilocularis potassium large conductance calcium activated 0.0039 0.0358 0.0378
Toxoplasma gondii hypothetical protein 0.008 0.0936 0.2421
Mycobacterium tuberculosis Probable hydrolase 0.0082 0.0972 0.1014
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Schistosoma mansoni nAChR subunit 0.0127 0.1601 0.2033
Echinococcus granulosus fmrfamide receptor 0.0061 0.0668 0.0722
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Onchocerca volvulus 0.0062 0.0681 0.0865
Trichomonas vaginalis tubulin epsilon chain, putative 0.0284 0.3812 0.9616
Echinococcus multilocularis Tubulin alpha 1 chain 0.021 0.2767 0.3054
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Leishmania major hypothetical protein, conserved 0.0082 0.0972 0.1231
Echinococcus granulosus potassium voltage gated channel protein 0.0039 0.0358 0.0378
Schistosoma mansoni nAChR subunit 0.0127 0.1601 0.2033
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0039 0.0358 0.0378
Schistosoma mansoni transient receptor potential channel 0.0039 0.0358 0.0437
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0161 0.0406
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0051 0.0526 0.134
Trypanosoma cruzi cytochrome P450, putative 0.0072 0.0832 0.2181
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.0972 0.2451
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.0936 0.1355
Echinococcus granulosus lysosomal alpha glucosidase 0.0076 0.0888 0.0966
Trichomonas vaginalis tubulin beta chain, putative 0.0284 0.3812 0.9616
Giardia lamblia Beta tubulin 0.0284 0.3812 1
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0092 0.0232
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Treponema pallidum exodeoxyribonuclease (exoA) 0.0024 0.0157 0.0103
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0029 0.0225 0.0231
Echinococcus granulosus dihydrofolate reductase 0.0043 0.0426 0.0453
Loa Loa (eye worm) voltage-gated calcium channel 0.0039 0.0358 0.0341
Echinococcus multilocularis microtubule associated protein 2 0.0365 0.4959 0.5488
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.006 0.0659 0.0946
Schistosoma mansoni tubulin subunit gamma 0.0152 0.1951 0.2483
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0092 0.0082
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0024 0.0157 0.0155
Mycobacterium ulcerans cell division protein FtsZ 0.0066 0.0743 0.0696
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0668 0.0835
Trichomonas vaginalis tubulin gamma chain, putative 0.0152 0.1951 0.4922
Leishmania major beta tubulin 0.0284 0.3812 0.483
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Brugia malayi Dihydrofolate reductase 0.0043 0.0426 0.0602
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0259 0.3461 0.3449
Brugia malayi sulfakinin receptor protein 0.0061 0.0668 0.0959
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0051 0.0526 0.051
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0039 0.0358 0.0378
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0039 0.0358 0.0378
Trypanosoma brucei alpha tubulin 0.021 0.2767 0.7259
Plasmodium falciparum ataxin-2 like protein, putative 0.0065 0.073 0.1876
Echinococcus granulosus transient receptor potential cation channel 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.008 0.0936 0.102
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Trichomonas vaginalis glucosylceramidase, putative 0.0105 0.1297 0.3273
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0062 0.0681 0.0737
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0051 0.0528 0.1385
Plasmodium falciparum alpha tubulin 2 0.021 0.2767 0.7246
Loa Loa (eye worm) acetylcholine receptor protein 0.0062 0.0681 0.0665
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Schistosoma mansoni tubulin subunit beta 0.0284 0.3812 0.4872
Loa Loa (eye worm) hypothetical protein 0.0046 0.047 0.0453
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Mycobacterium ulcerans monoamine oxidase 0.0051 0.0526 0.0477
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0039 0.0358 0.0378
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0066 0.0743 0.1874
Trichomonas vaginalis tubulin epsilon chain, putative 0.021 0.2767 0.6981
Echinococcus granulosus voltage gated hydrogen channel 1 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.021 0.2767 0.2754
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0053 0.0135
Trichomonas vaginalis glucosylceramidase, putative 0.0111 0.1377 0.3474
Trichomonas vaginalis tubulin gamma chain, putative 0.0284 0.3812 0.9616
Loa Loa (eye worm) hypothetical protein 0.0023 0.0138 0.012
Toxoplasma gondii thioredoxin reductase 0.0057 0.0614 0.157
Schistosoma mansoni neurotransmitter gated ion channel 0.0062 0.0681 0.0852
Echinococcus granulosus nAChR subunit 0.0127 0.1601 0.1758
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0024 0.0157 0.014
Trichomonas vaginalis tubulin gamma chain, putative 0.0066 0.0743 0.1874
Echinococcus granulosus Tubulin alpha 1 chain 0.021 0.2767 0.3054
Leishmania major dihydrofolate reductase-thymidylate synthase 0.015 0.1924 0.2437
Loa Loa (eye worm) hypothetical protein 0.008 0.0936 0.092
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0062 0.0681 0.0979
Schistosoma mansoni hypothetical protein 0.0061 0.0668 0.0835
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0437 0.0539
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0062 0.0681 0.0665
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0127 0.1601 0.1758
Echinococcus multilocularis nAChR subunit 0.0065 0.0735 0.0796
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.043 0.0458
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0035 0.0305 0.0253
Giardia lamblia Alpha-tubulin 0.021 0.2767 0.7246
Echinococcus granulosus peroxisome assembly protein 26 0.021 0.2767 0.3054
Schistosoma mansoni hypothetical protein 0.0038 0.0344 0.0419
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0092 0.0241
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Trypanosoma cruzi tubulin delta chain 0.0066 0.0743 0.1948
Loa Loa (eye worm) hypothetical protein 0.0057 0.0617 0.06
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0469 0.642 0.8221
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0014 0.0018 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0138 0.0177
Entamoeba histolytica phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0111 0.1377 0.3474
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0035 0.0305 0.0253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0092 0.0241
Echinococcus granulosus orexin receptor type 2 0.0061 0.0668 0.0722
Echinococcus multilocularis sodium and chloride dependent glycine 0.008 0.0936 0.102
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0092 0.0241
Brugia malayi Dopamine receptor protein 1 0.0061 0.0668 0.0959
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.043 0.0529
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0138 0.0083
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0668 0.0722
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.043 0.0458
Trichomonas vaginalis esterase, putative 0.0082 0.0972 0.2451
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0082 0.0972 0.0955
Echinococcus multilocularis survival motor neuron protein 1 0.0125 0.1578 0.1733
Schistosoma mansoni biogenic amine receptor 0.0061 0.0668 0.0835
Echinococcus granulosus small conductance calcium activated potassium 0.0167 0.2161 0.238
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0035 0.0305 0.0286
Echinococcus multilocularis hyperpolarization activated cyclic 0.0042 0.04 0.0425
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0042 0.04 0.0383
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Giardia lamblia Delta tubulin 0.0066 0.0743 0.1911
Schistosoma mansoni cellular tumor antigen P53 0.0096 0.1163 0.147
Trichomonas vaginalis tubulin beta chain, putative 0.021 0.2767 0.6981
Echinococcus granulosus serotonin transporter 0.0469 0.642 0.711
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.0936 0.2421
Plasmodium vivax delta tubulin, putative 0.0066 0.0743 0.1532
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0021 0.0107 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0127 0.1601 0.1758
Brugia malayi Carboxylesterase family protein 0.0046 0.047 0.0667
Trichomonas vaginalis tubulin beta chain, putative 0.021 0.2767 0.6981
Echinococcus granulosus nAChR subunit 0.0065 0.0735 0.0796
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus multilocularis tubulin alpha 0.0152 0.1951 0.2147
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0668 0.0722
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0437 0.1103
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) hypothetical protein 0.0065 0.0735 0.0718
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.008 0.0936 0.102
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0138 0.0083
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0668 0.0722
Plasmodium vivax tubulin epsilon chain, putative 0.0152 0.1951 0.4086
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.04 0.0491
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0144 0.1839 0.1961
Mycobacterium ulcerans dehydrogenase 0.0051 0.0526 0.0477
Onchocerca volvulus 0.0061 0.0668 0.0844
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0041 0.0394 0.0377
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0668 0.0722
Echinococcus granulosus expressed protein 0.0232 0.3089 0.341
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.008 0.0936 0.092
Onchocerca volvulus Putative nachr subunit 0.0127 0.1601 0.2329
Trichomonas vaginalis tubulin beta chain, putative 0.021 0.2767 0.6981
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0668 0.0722
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0024 0.0157 0.0199
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0668 0.0652
Trypanosoma cruzi PAB1-binding protein , putative 0.0065 0.073 0.1914
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0066 0.0743 1
Trypanosoma cruzi cytochrome P450, putative 0.0072 0.0832 0.2181
Echinococcus multilocularis Tubulin alpha 1 chain 0.021 0.2767 0.3054
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0474 0.1202
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.008 0.0936 0.2421
Echinococcus multilocularis tubulin subunit beta 0.0284 0.3812 0.4214
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0061 0.0668 0.0959
Loa Loa (eye worm) hypothetical protein 0.0065 0.0735 0.0718
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) tubulin alpha chain 0.021 0.2767 0.2754
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0066 0.0743 0.1911
Plasmodium vivax ataxin-2 like protein, putative 0.0065 0.073 0.1504
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0053 0.0135
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0127 0.1601 0.1758
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0127 0.1601 0.1758
Echinococcus multilocularis nAChR subunit 0.0127 0.1601 0.1758
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0092 0.0195
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0668 0.0722
Brugia malayi neuropeptide F receptor 0.0061 0.0668 0.0959
Loa Loa (eye worm) BEN-1 protein 0.0284 0.3812 0.3801
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0053 0.0135
Entamoeba histolytica hypothetical protein 0.0021 0.0107 0.0281
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.04 0.0491
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) hypothetical protein 0.0044 0.043 0.0413
Echinococcus multilocularis allatostatin A receptor 0.0061 0.0668 0.0722
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0127 0.1601 0.2033
Schistosoma mansoni amine GPCR 0.0061 0.0668 0.0835
Schistosoma mansoni glutaminase 0.0238 0.3164 0.404
Schistosoma mansoni transient receptor potential channel 4 0.0039 0.0358 0.0437
Brugia malayi alpha-tubulin 0.021 0.2767 0.4056
Brugia malayi Tubulin beta chain 0.0086 0.1024 0.1484
Trichomonas vaginalis tubulin epsilon chain, putative 0.0066 0.0743 0.1874
Echinococcus multilocularis sex peptide receptor 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Echinococcus granulosus neuropeptide receptor 0.0061 0.0668 0.0722
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0443 0.6048 0.8895
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0061 0.0668 0.0722
Trypanosoma brucei glucosidase, putative 0.0017 0.0053 0.014
Schistosoma mansoni neuropeptide receptor 0.0061 0.0668 0.0835
Schistosoma mansoni tubulin subunit alpha 0.021 0.2767 0.3531
Schistosoma mansoni alpha tubulin 0.021 0.2767 0.3531
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0039 0.0358 0.0378
Trichomonas vaginalis penicillin-binding protein, putative 0.0082 0.0972 0.2451
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Onchocerca volvulus Serine\/threonine kinase homolog 0.0044 0.0437 0.0477
Trichomonas vaginalis tubulin beta chain, putative 0.021 0.2767 0.6981
Schistosoma mansoni ets-related 0.0125 0.1571 0.1995
Onchocerca volvulus 0.0254 0.3386 0.517
Echinococcus multilocularis lamin dm0 0.0067 0.0753 0.0816
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0127 0.1601 0.2033
Onchocerca volvulus 0.0067 0.0753 0.0979
Onchocerca volvulus 0.0061 0.0668 0.0844
Echinococcus multilocularis hypothetical protein 0.021 0.2767 0.3054
Onchocerca volvulus 0.0061 0.0668 0.0844
Brugia malayi PAS domain containing protein 0.0032 0.0259 0.0356
Schistosoma mansoni calcium-activated potassium channel 0.0167 0.2161 0.2752
Mycobacterium ulcerans hypothetical protein 0.0023 0.0138 0.0083
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0043 0.0426 0.0375
Onchocerca volvulus 0.0061 0.0668 0.0844
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0092 0.0241
Schistosoma mansoni hypothetical protein 0.0061 0.0668 0.0835
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.0936 0.1355
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0035 0.0305 0.0801
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0067 0.0753 0.0736
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0144 0.1839 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.04 0.101
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0035 0.0305 0.0286
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0437 0.1103
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0106 0.1313 0.1663
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0014 0.0018 0.0047
Onchocerca volvulus Neuropeptide F receptor homolog 0.0061 0.0668 0.0844
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0092 0.0116
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0972 0.2548
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.021 0.2767 0.6981
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0039 0.0358 0.035
Plasmodium vivax tubulin alpha chain, putative 0.021 0.2767 0.581
Onchocerca volvulus 0.0127 0.1601 0.2329
Trichomonas vaginalis tubulin, putative 0.0086 0.1024 0.2583
Trichomonas vaginalis glucosylceramidase, putative 0.016 0.2074 0.5232
Echinococcus granulosus glycine receptor subunit alpha 1 0.0127 0.1601 0.1758
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Schistosoma mansoni nAChR subunit 0.0062 0.0681 0.0852
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0092 0.0241
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0161 0.0159
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0039 0.0358 0.0501
Onchocerca volvulus 0.0127 0.1601 0.2329
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0024 0.0157 0.1004
Leishmania major beta tubulin 0.0284 0.3812 0.483
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0017 0.0053 0.014
Echinococcus granulosus tubulin epsilon chain 0.0152 0.1951 0.2147
Loa Loa (eye worm) GABA receptor subunit 0.0065 0.0735 0.0718
Trichomonas vaginalis glutaminase, putative 0.0238 0.3164 0.7981
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.0351 0.475 1
Onchocerca volvulus 0.0127 0.1601 0.2329
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0035 0.0305 0.0253
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0043 0.0426 0.1694
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Leishmania major alpha glucosidase II subunit, putative 0.0017 0.0053 0.0068
Loa Loa (eye worm) acetyltransferase 0.0174 0.2259 0.2245
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0144 0.184 0.4641
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0039 0.0358 0.0378
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0129 0.1636 0.1739
Loa Loa (eye worm) beta-lactamase 0.0082 0.0972 0.0955
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Trypanosoma cruzi polo-like protein kinase, putative 0.0044 0.0437 0.1147
Loa Loa (eye worm) cytochrome P450 family protein 0.0072 0.0832 0.0815
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Schistosoma mansoni voltage-dependent calcium channel 0.0039 0.0358 0.0437
Leishmania major beta tubulin 0.0284 0.3812 0.483
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0035 0.0305 0.0286
Brugia malayi dihydrofolate reductase family protein 0.0043 0.0426 0.0602
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0035 0.0305 0.0253
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0036 0.0319 0.0334
Mycobacterium tuberculosis Conserved protein 0.0082 0.0972 0.1014
Leishmania major beta tubulin 0.0284 0.3812 0.483
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0138 0.0083
Echinococcus granulosus potassium voltage gated channel subfamily H 0.006 0.0659 0.0712
Onchocerca volvulus 0.0061 0.0668 0.0844
Trypanosoma cruzi alpha tubulin, putative 0.021 0.2767 0.7259
Brugia malayi Cytochrome P450 family protein 0.0035 0.0305 0.0424
Echinococcus multilocularis potassium voltage gated channel protein 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0092 0.0241
Schistosoma mansoni tubulin subunit epsilon 0.0152 0.1951 0.2483
Onchocerca volvulus 0.0065 0.0735 0.0951
Echinococcus multilocularis Tubulin alpha 1 chain 0.021 0.2767 0.3054
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Brugia malayi Transient-receptor-potential like protein 0.0039 0.0358 0.0501
Trypanosoma cruzi epsilon tubulin, putative 0.0152 0.1951 0.5118
Onchocerca volvulus 0.0061 0.0668 0.0844
Echinococcus granulosus dro:myosuppressin receptor 0.0061 0.0668 0.0722
Brugia malayi Tubulin alpha chain 0.0066 0.0743 0.1069
Loa Loa (eye worm) hypothetical protein 0.0065 0.0735 0.0718
Echinococcus granulosus Tubulin beta 2C chain 0.0284 0.3812 0.4214
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0305 0.0984
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Mycobacterium tuberculosis Conserved hypothetical protein 0.0051 0.0526 0.0528
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0026 0.0175 0.0232
Echinococcus granulosus tubulin alpha 0.0152 0.1951 0.2147
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0092 0.0195
Schistosoma mansoni myosin xvIII 0.0061 0.0668 0.0835
Leishmania major trypanothione reductase 0.0057 0.0614 0.0777
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0056 0.0014
Brugia malayi voltage-dependent calcium channel 0.0039 0.0358 0.0501
Loa Loa (eye worm) hypothetical protein 0.0051 0.0526 0.051
Mycobacterium ulcerans oxidoreductase 0.0051 0.0526 0.0477
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0039 0.0358 0.0501
Brugia malayi ion channel NompC 0.0039 0.0358 0.0501
Echinococcus multilocularis somatostatin receptor 0.0061 0.0668 0.0722
Trichomonas vaginalis glucosylceramidase, putative 0.016 0.2074 0.5232
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0614 0.0662
Trypanosoma cruzi zeta tubulin, putative 0.0066 0.0743 0.1948
Schistosoma mansoni sodium/chloride dependent transporter 0.0469 0.642 0.8221
Echinococcus multilocularis tubulin alpha 3 chain 0.021 0.2767 0.3054
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0743 0.1874
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0056 0.0101
Echinococcus multilocularis Tubulin beta 2C chain 0.0284 0.3812 0.4214
Onchocerca volvulus 0.0061 0.0668 0.0844
Schistosoma mansoni aryl hydrocarbon receptor 0.0032 0.0259 0.031
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) melatonin receptor type 1A 0.0061 0.0668 0.0652
Schistosoma mansoni tubulin subunit delta 0.0066 0.0743 0.0931
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Echinococcus multilocularis tubulin alpha chain 0.021 0.2767 0.3054
Echinococcus multilocularis calcium activated potassium channel 0.0039 0.036 0.038
Echinococcus granulosus glycine receptor subunit beta 0.0127 0.1601 0.1758
Trypanosoma brucei epsilon tubulin 0.0152 0.1951 0.5118
Brugia malayi Cation transporter family protein 0.0127 0.1601 0.2336
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0437 0.1103
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0051 0.0526 0.0653
Onchocerca volvulus 0.0295 0.3964 0.6091
Echinococcus granulosus g protein coupled receptor 0.0061 0.0668 0.0722
Brugia malayi hypothetical protein 0.0076 0.0883 0.1276
Schistosoma mansoni calcium-activated potassium channel 0.0128 0.162 0.2057
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0061 0.0668 0.0959
Schistosoma mansoni alpha-glucosidase 0.0066 0.0739 0.0926
Echinococcus granulosus survival motor neuron protein 1 0.0125 0.1578 0.1733
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0039
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0127 0.1601 0.2033
Plasmodium falciparum alpha tubulin 1 0.021 0.2767 0.7246
Brugia malayi RE15519p 0.0061 0.0668 0.0959
Echinococcus multilocularis protoporphyrinogen oxidase 0.0051 0.0526 0.0565
Loa Loa (eye worm) hypothetical protein 0.0096 0.1163 0.1147
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0062 0.0681 0.0737
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0129 0.1636 0.1739
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0161 0.0406
Entamoeba histolytica serine/threonine protein kinase, putative 0.0044 0.0437 0.1147
Schistosoma mansoni amine GPCR 0.0061 0.0668 0.0835
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0092 0.0241
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Plasmodium vivax hypothetical protein, conserved 0.008 0.0936 0.1941
Trichomonas vaginalis glucosylceramidase, putative 0.0105 0.1297 0.3273
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0053 0.0135
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0046 0.0075
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0039 0.0358 0.0437
Echinococcus granulosus two pore calcium channel protein 1 0.0039 0.0358 0.0378
Mycobacterium tuberculosis Probable lipase LipE 0.0082 0.0972 0.1014
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus granulosus calcium activated potassium channel 0.0039 0.036 0.038
Brugia malayi Dopamine receptor 0.0061 0.0668 0.0959
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0053 0.0135
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0061 0.0668 0.0722
Trichomonas vaginalis tubulin alpha chain, putative 0.0152 0.1951 0.4922
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0668 0.0722
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0668 0.0722
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.0035 0.031 0.0293
Schistosoma mansoni ap endonuclease 0.0024 0.0157 0.0179
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0039 0.0358 0.0437
Trichomonas vaginalis tubulin alpha chain, putative 0.0284 0.3812 0.9616
Giardia lamblia Beta tubulin 0.0284 0.3812 1
Brugia malayi Cytochrome P450 family protein 0.0072 0.0832 0.12
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0668 0.0722
Loa Loa (eye worm) thymidylate synthase 0.0106 0.1313 0.1298
Trypanosoma brucei PAB1-binding protein , putative 0.0065 0.073 0.1914
Loa Loa (eye worm) hypothetical protein 0.0042 0.04 0.0383
Brugia malayi hypothetical protein 0.0065 0.073 0.105
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0039 0.0358 0.0437
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0061 0.0668 0.0652
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0039 0.0358 0.0501
Echinococcus multilocularis glycine receptor subunit beta 0.0127 0.1601 0.1758
Brugia malayi Tubulin beta-1 chain 0.0284 0.3812 0.5597
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0668 0.0722
Mycobacterium leprae cell division protein FtsZ 0.0066 0.0743 0.3555
Brugia malayi Cell division protein ftsZ 0.0066 0.0743 0.1069
Onchocerca volvulus 0.008 0.0936 0.1271
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0039 0.0358 0.0378
Echinococcus granulosus uncharacterized sodium dependent transporter 0.008 0.0936 0.102
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0035 0.0305 0.0286
Echinococcus multilocularis 0.0051 0.0526 0.0565
Trypanosoma brucei cytochrome P450, putative 0.0072 0.0832 0.2181
Brugia malayi AKH receptor 0.0061 0.0668 0.0959
Schistosoma mansoni hypothetical protein 0.0017 0.006 0.0054
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.015 0.1924 0.5046
Echinococcus multilocularis voltage dependent calcium channel 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0051 0.0526 0.2284
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.008 0.0936 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.0936 0.118
Echinococcus granulosus short transient receptor potential channel 6 0.0039 0.0358 0.0378
Schistosoma mansoni hypothetical protein 0.0021 0.0107 0.0115
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0024 0.0157 0.0368
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0061 0.0668 0.0652
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0127 0.1601 0.1758
Onchocerca volvulus 0.0023 0.0144 0.001
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0127 0.1601 0.1758
Schistosoma mansoni dihydrofolate reductase 0.0043 0.0426 0.0524
Entamoeba histolytica tubulin gamma chain 0.0152 0.1951 0.5118
Brugia malayi hypothetical protein 0.0062 0.0681 0.0979
Schistosoma mansoni hypothetical protein 0.0061 0.0668 0.0835
Loa Loa (eye worm) hypothetical protein 0.0082 0.0972 0.0955
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Echinococcus granulosus serotonin receptor 0.0061 0.0668 0.0722
Plasmodium falciparum tubulin epsilon chain, putative 0.0152 0.1951 0.5096
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0035 0.0305 0.0387
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0035 0.0305 0.0286
Schistosoma mansoni amine GPCR 0.0061 0.0668 0.0835
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.008 0.0936 0.118
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0082 0.0972 0.1014
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.006 0.0659 0.0712
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus multilocularis transient receptor potential gamma protein 0.0039 0.0358 0.0378
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0039 0.0358 0.0501
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0018 0.0047
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.04 0.0491
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0668 0.0722
Schistosoma mansoni hypothetical protein 0.0242 0.3219 0.411
Plasmodium falciparum thioredoxin reductase 0.0057 0.0614 0.157
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0056 0.0081
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0589 0.0843
Brugia malayi Dopamine receptor protein 2 0.0061 0.0668 0.0959
Giardia lamblia Epsilon tubulin 0.0066 0.0743 0.1911
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0127 0.1601 0.2336
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0014 0.0018 0.0023
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0042 0.04 0.0425
Plasmodium falciparum tubulin gamma chain 0.0152 0.1951 0.5096
Echinococcus granulosus neutral alpha glucosidase AB 0.0017 0.0053 0.004
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0717 0.9912 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Loa Loa (eye worm) hypothetical protein 0.0065 0.073 0.0713
Brugia malayi Glycosyl hydrolases family 31 protein 0.0017 0.0053 0.0052
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0338 0.0411
Loa Loa (eye worm) hypothetical protein 0.0082 0.0972 0.0955
Echinococcus multilocularis tubulin delta chain 0.0066 0.0743 0.0805
Loa Loa (eye worm) hypothetical protein 0.0055 0.0589 0.0572
Echinococcus multilocularis two pore calcium channel protein 1 0.0039 0.0358 0.0378
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0035 0.0305 0.0253
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0589 0.0572
Brugia malayi hypothetical protein 0.0106 0.1305 0.1899
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0138 0.0103
Schistosoma mansoni neuropeptide receptor 0.0061 0.0668 0.0835
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0534 0.1347
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0044 0.043 0.0608
Loa Loa (eye worm) hypothetical protein 0.0179 0.2338 0.2324
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0525 0.7202 0.7817
Echinococcus granulosus sodium and chloride dependent glycine 0.008 0.0936 0.102
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0496 0.6797 0.6791
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0614 0.1259
Loa Loa (eye worm) hypothetical protein 0.0065 0.0735 0.0718
Echinococcus granulosus tubulin subunit beta 0.0284 0.3812 0.4214
Echinococcus granulosus tubulin alpha chain 0.021 0.2767 0.3054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0338 0.0411
Echinococcus granulosus lysine specific histone demethylase 1A 0.0051 0.0526 0.0565
Mycobacterium tuberculosis Conserved protein 0.0082 0.0972 0.1014
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Entamoeba histolytica tubulin alpha-1 chain 0.021 0.2767 0.7259
Echinococcus multilocularis tubulin alpha chain 0.021 0.2767 0.3054
Plasmodium falciparum tubulin beta chain 0.0284 0.3812 1
Trypanosoma brucei alpha tubulin 0.021 0.2767 0.7259
Schistosoma mansoni nAChR subunit 0.0127 0.1601 0.2033
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0138 0.0175
Toxoplasma gondii histone lysine-specific demethylase 0.0051 0.0526 0.134
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus granulosus histone acetyltransferase KAT2B 0.0169 0.219 0.2413
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0127 0.1601 0.1586
Echinococcus multilocularis dro:myosuppressin receptor 0.0061 0.0668 0.0722
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0668 0.0722
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0138 0.0083
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0039
Echinococcus multilocularis tubulin beta 1 chain 0.0284 0.3812 0.4214
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0344 0.0481
Trypanosoma brucei beta tubulin 0.0284 0.3812 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0092 0.0241
Schistosoma mansoni hypothetical protein 0.0026 0.0175 0.0202
Schistosoma mansoni tubulin subunit beta 0.0284 0.3812 0.4872
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0039 0.0358 0.0938
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0092 0.0036
Echinococcus multilocularis peroxisome assembly protein 26 0.021 0.2767 0.3054
Trichomonas vaginalis glucosylceramidase, putative 0.016 0.2074 0.5232
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0668 0.0835
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0668 0.0835
Trypanosoma cruzi beta tubulin, putative 0.0284 0.3812 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Mycobacterium ulcerans glutaminase 0.0238 0.3164 0.3153
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0526 0.1075
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0082 0.0972 0.1014
Leishmania major hypothetical protein, conserved 0.0039 0.0358 0.0453
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0072 0.0832 0.0787
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) transcription factor SMAD2 0.0172 0.2231 0.2217
Trichomonas vaginalis ap endonuclease, putative 0.0024 0.0157 0.0397
Echinococcus granulosus tubulin gamma 1 chain 0.0152 0.1951 0.2147
Brugia malayi hypothetical protein 0.0039 0.0358 0.0501
Trichomonas vaginalis tubulin epsilon chain, putative 0.021 0.2767 0.6981
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0039 0.0358 0.0501
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0053 0.014
Mycobacterium tuberculosis Probable lipase LipD 0.0082 0.0972 0.1014
Mycobacterium tuberculosis Possible oxidoreductase 0.0051 0.0526 0.0528
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0668 0.0835
Echinococcus granulosus potassium voltage gated channel protein 0.0039 0.0358 0.0378
Echinococcus multilocularis sodium and chloride dependent glycine 0.008 0.0936 0.102
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0092 0.0109
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0152 0.1951 0.5096
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0039 0.0358 0.0378
Echinococcus granulosus g protein coupled receptor 0.0061 0.0668 0.0722
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.006 0.0062
Entamoeba histolytica hypothetical protein 0.0021 0.0107 0.0281
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0065 0.0735 0.0921
Loa Loa (eye worm) solute carrier family 6 member 4 0.0469 0.642 0.6414
Toxoplasma gondii hypothetical protein 0.008 0.0936 0.2421
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0039 0.0358 0.0501
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0437 0.1103
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0717 0.9912 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0474 0.1243
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0035 0.0305 0.0286
Onchocerca volvulus 0.0127 0.1601 0.2329
Loa Loa (eye worm) voltage-gated potassium channel 0.0039 0.0358 0.0341
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0061 0.0668 0.0835
Brugia malayi hypothetical protein 0.0062 0.0681 0.0979
Loa Loa (eye worm) tubulin alpha-3 chain 0.0124 0.1559 0.1544
Loa Loa (eye worm) hypothetical protein 0.0082 0.0972 0.0955
Brugia malayi cation channel family protein 0.0039 0.0358 0.0501
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0668 0.0835
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Schistosoma mansoni hypothetical protein 0.0017 0.006 0.0054
Loa Loa (eye worm) tubulin beta chain 0.0066 0.0743 0.0726
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0284 0.3812 0.4214
Loa Loa (eye worm) hypothetical protein 0.0082 0.0972 0.0955
Brugia malayi Carboxylesterase family protein 0.0046 0.047 0.0667
Trypanosoma brucei zeta tubulin 0.0066 0.0743 0.1948
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0179 0.2338 0.2576
Loa Loa (eye worm) acetylcholinesterase 1 0.0046 0.047 0.0453
Echinococcus multilocularis transfer RNA-Lys 0.0023 0.0144 0.014
Brugia malayi hypothetical protein 0.0051 0.0526 0.075
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0039 0.0358 0.0437
Trichomonas vaginalis ap endonuclease, putative 0.0024 0.0157 0.0397
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0127 0.1601 0.2336
Echinococcus multilocularis neuropeptide FF receptor 2 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.008 0.0936 0.092
Schistosoma mansoni tubulin subunit alpha 0.021 0.2767 0.3531
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0044 0.0437 0.0554
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0668 0.0722
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0039 0.0358 0.0378
Brugia malayi Cyclic-nucleotide gated cation channel 0.0042 0.04 0.0564
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Leishmania major beta tubulin 0.0284 0.3812 0.483
Echinococcus multilocularis GPCR, family 2 0.0017 0.006 0.0047
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus granulosus GPCR family 2 0.0017 0.006 0.0047
Leishmania major beta tubulin 0.0284 0.3812 0.483
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0338 0.0356
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0024 0.0157 0.0368
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0127 0.1601 0.2336
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0127 0.1601 0.1758
Echinococcus multilocularis g-protein coupled receptor 0.0061 0.0668 0.0722
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0124 0.1559 0.3932
Echinococcus granulosus g protein coupled receptor 0.0061 0.0668 0.0722
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Leishmania major delta tubulin, putative 0.0066 0.0743 0.0941
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Onchocerca volvulus 0.0039 0.0358 0.035
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0179 0.2338 0.2576
Onchocerca volvulus 0.0065 0.0735 0.0951
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0668 0.0835
Onchocerca volvulus 0.0127 0.1601 0.2329
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0062 0.0681 0.0737
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0589 0.0843
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0014 0.0018 0.0045
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0092 0.0241
Echinococcus granulosus Tubulin beta 2C chain 0.0284 0.3812 0.4214
Brugia malayi hypoxia-induced factor 1 0.0098 0.119 0.1729
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.008 0.0936 0.102
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0051 0.0526 0.1075
Toxoplasma gondii hypothetical protein 0.0039 0.0358 0.0896
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0138 0.0361
Loa Loa (eye worm) voltage-gated potassium channel 0.0039 0.0358 0.0341
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0092 0.0157
Echinococcus multilocularis geminin 0.0568 0.7805 0.8649
Loa Loa (eye worm) hypothetical protein 0.0065 0.0735 0.0718
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0042 0.04 0.0425
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0061 0.0668 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0528 0.1331
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0668 0.0722
Echinococcus multilocularis transient receptor potential cation channel 0.0039 0.0358 0.0378
Echinococcus multilocularis potassium voltage gated channel protein 0.0039 0.0358 0.0378
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0061 0.0668 0.0722
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0039 0.0358 0.0378
Schistosoma mansoni hypothetical protein 0.0035 0.0305 0.0369
Echinococcus granulosus tubulin alpha chain 0.021 0.2767 0.3054
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0144 0.1839 0.1961
Echinococcus granulosus acetylcholinesterase 0.0046 0.047 0.0502
Trichomonas vaginalis maltase-glucoamylase, putative 0.0017 0.0053 0.0135
Toxoplasma gondii alpha-tubulin I, putative 0.021 0.2767 0.7246
Echinococcus multilocularis lysosomal alpha glucosidase 0.0076 0.0888 0.0966
Echinococcus multilocularis orexin receptor type 2 0.0061 0.0668 0.0722
Echinococcus granulosus potassium large conductance calcium activated 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0065 0.0735 0.0718
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0437 0.1103
Brugia malayi acetyltransferase, GNAT family protein 0.0174 0.2259 0.3305
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0051 0.0526 0.1075
Brugia malayi ORL1-like opioid receptor 0.0061 0.0668 0.0959
Schistosoma mansoni neuropeptide f receptor 76f 0.0061 0.0668 0.0835
Echinococcus granulosus 7tm_1 domain containing protein 0.0061 0.0668 0.0722
Brugia malayi Cation transporter family protein 0.0127 0.1601 0.2336
Brugia malayi Pre-SET motif family protein 0.0259 0.3461 0.5079
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0338 0.0844
Echinococcus multilocularis voltage dependent calcium channel 0.0039 0.0358 0.0378
Toxoplasma gondii transporter, cation channel family protein 0.0039 0.0358 0.0896
Loa Loa (eye worm) cytochrome P450 0.0035 0.0305 0.0288
Trypanosoma brucei tubulin delta chain 0.0066 0.0743 0.1948
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0668 0.0835
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus granulosus geminin 0.0568 0.7805 0.8649
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0138 0.0177
Toxoplasma gondii hypothetical protein 0.0039 0.0358 0.0896
Echinococcus granulosus tubulin beta 1 chain 0.0284 0.3812 0.4214
Toxoplasma gondii transporter, cation channel family protein 0.0039 0.0358 0.0896
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0129 0.1636 0.1739
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0092 0.0116
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0018 0.0047
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0127 0.1601 0.2336
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0035 0.0305 0.0253
Schistosoma mansoni hypothetical protein 0.0242 0.3219 0.411
Trypanosoma brucei beta tubulin 0.0284 0.3812 1
Echinococcus granulosus beta tubulin 0.0284 0.3812 0.4214
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0042 0.04 0.0425
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0668 0.0835
Echinococcus granulosus tubulin alpha 3 chain 0.021 0.2767 0.3054
Schistosoma mansoni two-pore calcium channel 0.0039 0.0358 0.0437
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Loa Loa (eye worm) ion channel NompC 0.0039 0.0358 0.0341
Echinococcus granulosus Tubulin beta 2C chain 0.0284 0.3812 0.4214
Schistosoma mansoni opsin-like receptor 0.0061 0.0668 0.0835
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0039 0.0358 0.0437
Echinococcus granulosus lamin 0.0067 0.0753 0.0816
Onchocerca volvulus 0.0061 0.0668 0.0844
Loa Loa (eye worm) RecQ helicase 0.0025 0.0161 0.0143
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0338 0.0356
Leishmania major beta tubulin 0.0284 0.3812 0.483
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0061 0.0668 0.0835
Entamoeba histolytica hypothetical protein 0.0021 0.0107 0.0281
Schistosoma mansoni cytochrome P450 0.0035 0.0305 0.0369
Toxoplasma gondii LsmAD domain-containing protein 0.0065 0.073 0.1876
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Brugia malayi Intermediate filament tail domain containing protein 0.0067 0.0753 0.1084
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0039 0.0358 0.0437
Echinococcus granulosus beta LACTamase domain containing family member 0.0082 0.0972 0.1059
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0039 0.0358 0.0501
Loa Loa (eye worm) alpha-tubulin 0.021 0.2767 0.2754
Echinococcus multilocularis short transient receptor potential channel 6 0.0039 0.0358 0.0378
Echinococcus granulosus two pore calcium channel protein 2 0.0039 0.0358 0.0378
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0042 0.04 0.0425
Giardia lamblia Beta tubulin 0.0284 0.3812 1
Echinococcus multilocularis two pore calcium channel protein 2 0.0039 0.0358 0.0378
Brugia malayi cytoplasmic intermediate filament protein 0.0036 0.0318 0.0442
Brugia malayi thymidylate synthase 0.0106 0.1313 0.1911
Brugia malayi Thioredoxin reductase 0.0057 0.0614 0.0879
Schistosoma mansoni alpha glucosidase 0.0017 0.0053 0.0046
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0024 0.0157 0.0125
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0051 0.0526 0.0477
Brugia malayi hypothetical protein 0.0062 0.0681 0.0979
Schistosoma mansoni single-minded 0.0032 0.0259 0.031
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0014 0.0019 0.0001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0251 0.0233
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0061 0.0668 0.0722
Echinococcus multilocularis tubulin alpha 3 chain 0.021 0.2767 0.3054
Onchocerca volvulus 0.0026 0.0175 0.0059
Schistosoma mansoni neuropeptide receptor 0.0061 0.0668 0.0835
Brugia malayi follicle stimulating hormone receptor 0.0496 0.6797 1
Loa Loa (eye worm) serotonin transporter b 0.0469 0.642 0.6414
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0039 0.0358 0.0378
Schistosoma mansoni gabp alpha 0.0041 0.0394 0.0483
Brugia malayi putative neuropeptide receptor 0.0061 0.0668 0.0959
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Schistosoma mansoni tubulin subunit beta 0.0284 0.3812 0.4872
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0035 0.0305 0.0286
Echinococcus granulosus GA binding protein alpha chain 0.0041 0.0394 0.0417
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Brugia malayi hypothetical protein 0.0125 0.1578 0.2301
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Leishmania major beta tubulin 0.0284 0.3812 0.483
Loa Loa (eye worm) tubulin beta-4 chain 0.0284 0.3812 0.3801
Echinococcus multilocularis tubulin gamma 1 chain 0.0152 0.1951 0.2147
Treponema pallidum sodium- and chloride- dependent transporter 0.0469 0.642 1
Onchocerca volvulus 0.0061 0.0668 0.0844
Toxoplasma gondii beta tubulin 0.0284 0.3812 1
Onchocerca volvulus 0.0067 0.0753 0.0979
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0039 0.0358 0.0378
Schistosoma mansoni acetylcholine receptor-related 0.0062 0.0681 0.0852
Mycobacterium leprae putative cytochrome p450 0.0035 0.0305 0.0984
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Echinococcus granulosus glycine receptor subunit alpha 1 0.0127 0.1601 0.1758
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0138 0.0083
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0338 0.0411
Echinococcus multilocularis ryanodine receptor 44f 0.0039 0.0358 0.0378
Echinococcus multilocularis potassium voltage gated channel protein 0.0039 0.0358 0.0378
Leishmania major cytochrome p450-like protein 0.0035 0.0305 0.0387
Loa Loa (eye worm) hypoxia-induced factor 1 0.0098 0.119 0.1174
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.0936 0.118
Echinococcus multilocularis neuropeptide receptor A26 0.0061 0.0668 0.0722
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Echinococcus granulosus hypothetical protein 0.0061 0.0668 0.0722
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0039 0.0358 0.0501
Entamoeba histolytica hypothetical protein 0.0021 0.0107 0.0281
Schistosoma mansoni lamin 0.0067 0.0753 0.0944
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0574 0.7893 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0044 0.0437 0.1147
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0138 0.0175
Trichomonas vaginalis tubulin alpha chain, putative 0.0086 0.1024 0.2583
Echinococcus granulosus tumor protein p63 0.0654 0.9022 1
Mycobacterium tuberculosis Probable esterase LipL 0.0082 0.0972 0.1014
Brugia malayi neuropeptide F receptor 0.0061 0.0668 0.0959
Schistosoma mansoni microtubule-associated protein tau 0.0365 0.4959 0.6345
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0106 0.1313 0.6907
Schistosoma mansoni acetylcholine receptor subunit beta 0.0062 0.0681 0.0852
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0017 0.0053 0.0036
Loa Loa (eye worm) ACC-1 protein 0.0127 0.1601 0.1586
Brugia malayi hypothetical protein 0.0254 0.3386 0.4968
Leishmania major beta tubulin 0.0284 0.3812 0.483
Loa Loa (eye worm) hypothetical protein 0.0023 0.0138 0.012
Toxoplasma gondii transporter, cation channel family protein 0.0039 0.0358 0.0896
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0065 0.0735 0.1058
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0161 0.0211
Schistosoma mansoni tubulin subunit alpha 0.0066 0.0743 0.0931
Brugia malayi Serotonin receptor 0.0061 0.0668 0.0959
Onchocerca volvulus 0.0106 0.1313 0.1871
Schistosoma mansoni hypothetical protein 0.0568 0.7805 1
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0039 0.0358 0.0378
Echinococcus granulosus transient receptor potential cation channel 0.0039 0.0358 0.0378
Brugia malayi beta-tubulin, identical 0.0284 0.3812 0.5597
Loa Loa (eye worm) dihydrofolate reductase 0.0043 0.0426 0.0409
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0127 0.1601 0.1758
Toxoplasma gondii ABC1 family protein 0.0082 0.0972 0.2514
Brugia malayi beta-lactamase family protein 0.0082 0.0972 0.1407
Loa Loa (eye worm) fli-1 protein 0.0125 0.1571 0.1556
Onchocerca volvulus 0.0044 0.0436 0.0474
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0035 0.0305 0.0286
Echinococcus multilocularis GA binding protein alpha chain 0.0041 0.0394 0.0417
Mycobacterium leprae conserved hypothetical protein 0.0082 0.0972 0.49
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0668 0.0835
Loa Loa (eye worm) hypothetical protein 0.0051 0.0526 0.051
Schistosoma mansoni voltage-gated cation channel 0.0039 0.0358 0.0437
Mycobacterium leprae Probable lipase LipE 0.0082 0.0972 0.49
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0035 0.0305 0.0253
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.008 0.0936 0.092
Onchocerca volvulus 0.0061 0.0668 0.0844
Trichomonas vaginalis glucosylceramidase, putative 0.0105 0.1297 0.3273
Echinococcus granulosus tubulin delta chain 0.0066 0.0743 0.0805
Loa Loa (eye worm) hypothetical protein 0.0125 0.1578 0.1563
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0668 0.0835
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0127 0.1601 0.2336
Loa Loa (eye worm) hypothetical protein 0.0204 0.2693 0.268
Echinococcus granulosus glycine receptor subunit beta 0.0127 0.1601 0.1758
Mycobacterium tuberculosis Hypothetical protein 0.0051 0.0528 0.0529
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0039 0.0358 0.0938
Mycobacterium tuberculosis Probable reductase 0.0129 0.1636 0.1739
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0092 0.0195
Trichomonas vaginalis CAMK family protein kinase 0.0022 0.0123 0.0311
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0179 0.2338 0.2979
Trypanosoma brucei beta tubulin 0.0152 0.1951 0.5118
Leishmania major beta tubulin 0.0284 0.3812 0.483
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0035 0.0305 0.0286
Echinococcus granulosus G protein coupled receptor 139 0.0061 0.0668 0.0722
Leishmania major beta tubulin 0.0284 0.3812 0.483
Schistosoma mansoni amine oxidase 0.0051 0.0526 0.0653
Echinococcus multilocularis tubulin subunit TubB 0.021 0.2767 0.3054
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0667 0.9201 1
Loa Loa (eye worm) hypothetical protein 0.0381 0.5181 0.5173
Leishmania major beta tubulin 0.0284 0.3812 0.483
Trichomonas vaginalis tubulin beta chain, putative 0.021 0.2767 0.6981
Schistosoma mansoni neuropeptide receptor 0.0061 0.0668 0.0835
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0042 0.04 0.0491
Echinococcus granulosus bloom syndrome protein 0.0025 0.0161 0.0159
Brugia malayi G-protein coupled receptor 0.0061 0.0668 0.0959
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0743 0.1874
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0668 0.0722
Loa Loa (eye worm) beta-tubulin 0.0284 0.3812 0.3801
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0668 0.0722
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0127 0.1601 0.2336
Mycobacterium ulcerans hypothetical protein 0.0082 0.0972 0.0929
Brugia malayi hypothetical protein 0.0042 0.0406 0.0572
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0534 0.109
Echinococcus multilocularis beta LACTamase domain containing family member 0.0082 0.0972 0.1059
Echinococcus granulosus intermediate filament protein 0.0067 0.0753 0.0816
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0668 0.0722
Leishmania major beta tubulin 0.0284 0.3812 0.483
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0035 0.0305 0.0253
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0061 0.0668 0.0959
Schistosoma mansoni tubulin subunit alpha 0.021 0.2767 0.3531
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0035 0.0305 0.0253
Plasmodium falciparum transporter, putative 0.008 0.0936 0.2421
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.015 0.1924 0.4028
Echinococcus multilocularis hyperpolarization activated cyclic 0.0042 0.04 0.0425
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Plasmodium falciparum glutathione reductase 0.0057 0.0614 0.157
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0614 0.0662
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0668 0.0835
Onchocerca volvulus 0.008 0.0936 0.1271
Loa Loa (eye worm) pip kinase 2 0.0179 0.2338 0.2324
Loa Loa (eye worm) hypothetical protein 0.008 0.0936 0.092
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Onchocerca volvulus 0.008 0.0936 0.1271
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0127 0.1601 0.2336
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0039 0.0358 0.0378
Plasmodium falciparum protoporphyrinogen oxidase 0.0051 0.0526 0.134
Echinococcus granulosus sodium channel protein 0.0574 0.7893 0.8746
Trichomonas vaginalis tubulin, putative 0.0066 0.0743 0.1874
Onchocerca volvulus 0.0062 0.0681 0.0865
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0035 0.0305 0.0253
Chlamydia trachomatis protoporphyrinogen oxidase 0.0051 0.0526 0.5341
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.008 0.0936 0.102
Loa Loa (eye worm) tubulin beta chain 0.0284 0.3812 0.3801
Echinococcus granulosus Tubulin alpha 1 chain 0.021 0.2767 0.3054
Trichomonas vaginalis tubulin alpha chain, putative 0.0086 0.1024 0.2583
Plasmodium falciparum amino acid transporter, putative 0.008 0.0936 0.2421
Loa Loa (eye worm) alpha-tubulin 0.021 0.2767 0.2754
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0039
Schistosoma mansoni histamine h1 receptor 0.0061 0.0668 0.0835
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0035 0.0305 0.0286
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0614 0.0623
Echinococcus multilocularis transfer RNA-Gly 0.0039 0.0358 0.0378
Echinococcus granulosus carboxylesterase 5A 0.0046 0.047 0.0502
Brugia malayi bHLH-PAS transcription factor 0.0023 0.0144 0.0186
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0138 0.0175
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0127 0.1601 0.1758
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0039 0.0358 0.0938
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0127 0.1601 0.2336
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0062 0.0681 0.0979
Brugia malayi glutathione reductase 0.0057 0.0614 0.0879
Echinococcus granulosus potassium voltage gated channel protein 0.0039 0.0358 0.0378
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0035 0.0305 0.0253
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0127 0.1601 0.1586
Echinococcus granulosus neuropeptide receptor A26 0.0061 0.0668 0.0722
Trypanosoma brucei hypothetical protein, conserved 0.0082 0.0972 0.2548
Brugia malayi Sodium:neurotransmitter symporter family protein 0.008 0.0936 0.1355
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0018 0.0047
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.008 0.0936 0.118
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0039 0.0358 0.035
Echinococcus granulosus tubulin alpha 1C chain 0.021 0.2767 0.3054
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0092 0.0036
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0092 0.0082
Giardia lamblia Kinase, PLK 0.0044 0.0437 0.1106
Plasmodium vivax hypothetical protein, conserved 0.0082 0.0972 0.2015
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0668 0.0652
Brugia malayi Ets-domain containing protein 0.0041 0.0394 0.0555
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0174 0.2259 0.2877
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.006 0.0047
Brugia malayi Tubulin beta chain 0.0066 0.0743 0.1069
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0061 0.0668 0.0835
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0082 0.0972 0.1225
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Plasmodium vivax tubulin beta chain, putative 0.0284 0.3812 0.8018
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0017 0.0053 0.0094
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0668 0.0835
Trichomonas vaginalis tubulin epsilon chain, putative 0.0284 0.3812 0.9616
Brugia malayi MH2 domain containing protein 0.0172 0.2231 0.3265
Echinococcus multilocularis small conductance calcium activated potassium 0.0167 0.2161 0.238
Schistosoma mansoni nAChR subunit 0.0127 0.1601 0.2033
Echinococcus multilocularis tubulin alpha chain 0.021 0.2767 0.3054
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0051 0.0526 0.0565
Loa Loa (eye worm) ryanodine receptor 0.0039 0.0358 0.0341
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.0972 0.2451
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0668 0.0722
Echinococcus granulosus alpha tubulin 0.021 0.2767 0.3054
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0127 0.1601 0.1586
Onchocerca volvulus 0.0051 0.0526 0.0619
Leishmania major cytochrome p450-like protein 0.0035 0.0305 0.0387
Loa Loa (eye worm) hypothetical protein 0.0082 0.0972 0.0955
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0018 0.0047
Schistosoma mansoni neurotransmitter gated ion channel 0.0065 0.0735 0.0921
Brugia malayi Cation transporter family protein 0.0127 0.1601 0.2336
Schistosoma mansoni transient receptor potential channel 0.0039 0.0358 0.0437
Echinococcus multilocularis Tubulin beta 2C chain 0.0284 0.3812 0.4214
Brugia malayi serine/threonine-protein kinase plk-2 0.0044 0.0437 0.0619
Entamoeba histolytica tubulin family protein 0.0284 0.3812 1
Schistosoma mansoni nAChR subunit 0.0127 0.1601 0.2033
Onchocerca volvulus 0.0037 0.0338 0.0319
Brugia malayi G protein-coupled receptor 0.0061 0.0668 0.0959
Trypanosoma brucei beta tubulin 0.0284 0.3812 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0387 0.0475
Schistosoma mansoni neurotransmitter gated ion channel 0.0062 0.0681 0.0852
Trichomonas vaginalis tubulin alpha chain, putative 0.0086 0.1024 0.2583
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0668 0.0722
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0035 0.0305 0.0253
Brugia malayi amine oxidase, flavin-containing family protein 0.0051 0.0526 0.075
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0039 0.0358 0.0378
Trypanosoma brucei alpha tubulin 0.021 0.2767 0.7259
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.008 0.0936 0.1355
Leishmania major zeta tubulin, putative 0.0066 0.0743 0.0941
Toxoplasma gondii alpha tubulin TUBA1 0.021 0.2767 0.7246
Schistosoma mansoni biogenic amine (5HT) receptor 0.0204 0.2693 0.3435
Leishmania major beta tubulin 0.0284 0.3812 0.483
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0305 0.0801
Echinococcus granulosus voltage dependent calcium channel 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0242 0.3219 0.3206
Echinococcus multilocularis transient receptor potential cation channel 0.0039 0.0358 0.0378
Leishmania major hypothetical protein, unknown function 0.0039 0.0358 0.0453
Brugia malayi Fli-1 protein 0.0125 0.1571 0.2292
Brugia malayi Serotonin receptor 0.0061 0.0668 0.0959
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0039 0.0358 0.0378
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0668 0.0835
Echinococcus multilocularis expressed protein 0.0232 0.3089 0.341
Leishmania major gamma-tubulin 0.0152 0.1951 0.2472
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0092 0.0405
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.016 0.2074 0.206
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0088 0.0091
Trypanosoma brucei alpha tubulin 0.021 0.2767 0.7259
Mycobacterium ulcerans beta-lactamase 0.0082 0.0972 0.0929
Loa Loa (eye worm) MH2 domain-containing protein 0.0172 0.2231 0.2217
Brugia malayi Ets-domain containing protein 0.0041 0.0394 0.0555
Echinococcus granulosus somatostatin receptor 0.0061 0.0668 0.0722
Schistosoma mansoni opsin-like receptor 0.0061 0.0668 0.0835
Entamoeba histolytica hypothetical protein 0.0065 0.0735 0.1928
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.0689 0.0862
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0024 0.0157 0.0155
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0127 0.1601 0.2336
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0065 0.0735 0.1058
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0106 0.1313 0.1387
Trichomonas vaginalis sucrase-isomaltase, putative 0.0017 0.0053 0.0135
Loa Loa (eye worm) TYRA-2 protein 0.0061 0.0668 0.0652
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0358 0.0437
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0014 0.0018 0.0047
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0042 0.04 0.0491
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0028 0.0209 0.0528
Loa Loa (eye worm) tubulin alpha chain 0.021 0.2767 0.2754
Loa Loa (eye worm) tubulin beta-2A chain 0.0284 0.3812 0.3801
Brugia malayi Cytochrome P450 family protein 0.0105 0.1297 0.1887
Loa Loa (eye worm) hypothetical protein 0.0124 0.1559 0.1544
Brugia malayi hypothetical protein 0.0051 0.0528 0.0752
Loa Loa (eye worm) hypothetical protein 0.0038 0.0344 0.0327
Brugia malayi hypothetical protein 0.0062 0.0681 0.0979
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0668 0.0722
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0062 0.0681 0.0665
Trypanosoma cruzi zeta tubulin, putative 0.0066 0.0743 0.1948
Schistosoma mansoni alpha tubulin 0.021 0.2767 0.3531
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.015 0.1924 0.5023
Brugia malayi Glycosyl hydrolases family 31 protein 0.0076 0.0888 0.1284
Loa Loa (eye worm) hypothetical protein 0.0039 0.0358 0.0341
Echinococcus granulosus lysine specific histone demethylase 1A 0.0051 0.0526 0.0565
Echinococcus multilocularis serotonin transporter 0.0469 0.642 0.711
Schistosoma mansoni calcium-activated potassium channel 0.0039 0.0358 0.0437
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0668 0.0722
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0039 0.0358 0.0501
Echinococcus multilocularis thymidylate synthase 0.0106 0.1313 0.1438
Brugia malayi hypothetical protein 0.0061 0.0668 0.0959
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0024 0.0157 0.0413
Plasmodium vivax SET domain protein, putative 0.0037 0.0338 0.0677
Echinococcus granulosus tubulin alpha 1C chain 0.021 0.2767 0.3054
Schistosoma mansoni nAChR subunit 0.0127 0.1601 0.2033
Loa Loa (eye worm) CYP4Cod1 0.0072 0.0832 0.0815
Brugia malayi Tubulin gamma chain 0.0152 0.1951 0.2852
Loa Loa (eye worm) hypothetical protein 0.0051 0.0526 0.051
Loa Loa (eye worm) hypothetical protein 0.0106 0.1305 0.129
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0127 0.1601 0.2033
Mycobacterium tuberculosis Cell division protein FtsZ 0.0066 0.0743 0.0764
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0129 0.1636 0.8806
Echinococcus multilocularis potassium voltage gated channel protein 0.0039 0.0358 0.0378
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0042 0.04 0.0425
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0138 0.0361
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0024 0.0157 0.0413
Loa Loa (eye worm) hypothetical protein 0.0065 0.0736 0.0719
Echinococcus multilocularis voltage gated potassium channel 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0037 0.0342 0.0325
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0061 0.0668 0.0722
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Onchocerca volvulus 0.0061 0.0668 0.0844
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) hypothetical protein 0.0062 0.0681 0.0665
Onchocerca volvulus 0.0061 0.0668 0.0844
Onchocerca volvulus 0.0061 0.0668 0.0844
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0039 0.0358 0.0501
Leishmania major epsilon tubulin, putative 0.0152 0.1951 0.2472
Echinococcus granulosus hypothetical protein 0.0039 0.0358 0.0378
Echinococcus granulosus transient receptor potential cation channel 0.0039 0.0358 0.0378
Loa Loa (eye worm) tubulin alpha-2 chain 0.021 0.2767 0.2754
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0127 0.1601 0.2336
Schistosoma mansoni hypothetical protein 0.0167 0.2161 0.2752
Schistosoma mansoni biogenic amine receptor 0.0061 0.0668 0.0835
Trichomonas vaginalis glucosylceramidase, putative 0.0105 0.1297 0.3273
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0035 0.0305 0.0286
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.0972 0.2451
Trichomonas vaginalis glucosylceramidase, putative 0.0105 0.1297 0.3273
Trypanosoma cruzi tubulin delta chain 0.0066 0.0743 0.1948
Loa Loa (eye worm) hypothetical protein 0.002 0.0091 0.0073
Echinococcus granulosus sodium leak channel non selective protein 0.0039 0.0358 0.0378
Echinococcus granulosus tubulin beta 4A class IVa 0.0284 0.3812 0.4214
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0042 0.04 0.0383
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0242 0.3219 0.3555
Echinococcus granulosus microtubule associated protein 2 0.0365 0.4959 0.5488
Trypanosoma cruzi UDP-galactopyranose mutase 0.0051 0.0526 0.1381
Trichomonas vaginalis penicillin-binding protein, putative 0.0082 0.0972 0.2451
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0061 0.0668 0.0835
Echinococcus granulosus g-protein coupled receptor 0.0061 0.0668 0.0722
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0042 0.04 0.0425
Loa Loa (eye worm) hypothetical protein 0.0254 0.3386 0.3374
Brugia malayi SWIRM domain containing protein 0.0051 0.0526 0.075
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0179 0.2338 0.2979
Loa Loa (eye worm) tubulin beta-1 chain 0.0284 0.3812 0.3801
Loa Loa (eye worm) hypothetical protein 0.0032 0.0268 0.025
Echinococcus granulosus lamin dm0 0.0067 0.0753 0.0816
Echinococcus multilocularis glycine receptor subunit beta 0.0127 0.1601 0.1758
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0144 0.184 0.1825
Trypanosoma brucei trypanothione reductase 0.0057 0.0614 0.1609
Echinococcus granulosus Tubulin beta 2C chain 0.0284 0.3812 0.4214
Echinococcus granulosus ryanodine receptor 44f 0.0039 0.0358 0.0378
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.016 0.2074 0.3033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0251 0.0233
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0127 0.1601 0.2336
Brugia malayi beta-lactamase family protein 0.0082 0.0972 0.1407
Loa Loa (eye worm) hypothetical protein 0.008 0.0936 0.092
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0127 0.1601 0.2336
Leishmania major beta tubulin 0.0284 0.3812 0.483
Plasmodium vivax tubulin gamma chain, putative 0.0152 0.1951 0.4086
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0061 0.0668 0.0835
Loa Loa (eye worm) tubulin alpha 2 0.0058 0.0631 0.0615
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0039 0.0358 0.0378
Onchocerca volvulus 0.0127 0.1601 0.2329
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0062 0.0681 0.0979
Mycobacterium tuberculosis Conserved protein 0.0082 0.0972 0.1014
Schistosoma mansoni kinase 0.0022 0.0131 0.0146
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0035 0.0305 0.0286
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0061 0.0668 0.0722
Echinococcus multilocularis neuropeptide s receptor 0.0061 0.0668 0.0722
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0065 0.0735 0.0921
Echinococcus multilocularis sodium leak channel non selective protein 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0037 0.0338 0.0321
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Toxoplasma gondii beta-tubulin, putative 0.0284 0.3812 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0264 0.0247
Plasmodium vivax glutathione reductase, putative 0.0057 0.0614 0.1259
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0014 0.0018 0.0023
Echinococcus granulosus voltage dependent calcium channel 0.0039 0.0358 0.0378
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Trichomonas vaginalis tubulin, putative 0.0086 0.1024 0.2583
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0668 0.0722
Onchocerca volvulus 0.0061 0.0668 0.0844
Brugia malayi G-protein coupled receptor 0.0061 0.0668 0.0959
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0092 0.0095
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0474 0.1202
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.016 0.2074 0.5232
Onchocerca volvulus 0.0082 0.0972 0.1327
Brugia malayi Tubulin alpha-2 chain 0.021 0.2767 0.4056
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0061 0.0668 0.0835
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0061 0.0668 0.0652
Loa Loa (eye worm) hypothetical protein 0.0167 0.2161 0.2147
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.04 0.101
Echinococcus granulosus short transient receptor potential channel 6 0.0039 0.0358 0.0378
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0061 0.0668 0.0959
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0061 0.0668 0.0835
Loa Loa (eye worm) hypothetical protein 0.0469 0.642 0.6414
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0668 0.0722
Toxoplasma gondii beta-1 tubulin, putative 0.0284 0.3812 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0029 0.0225 0.0231
Onchocerca volvulus 0.0086 0.1024 0.141
Brugia malayi intermediate filament protein 0.0067 0.0753 0.1084
Brugia malayi exodeoxyribonuclease III family protein 0.0024 0.0157 0.0206
Trichomonas vaginalis tubulin beta chain, putative 0.0086 0.1024 0.2583
Echinococcus granulosus voltage gated potassium channel 0.0044 0.043 0.0458
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Brugia malayi Latrophilin receptor protein 2 0.0017 0.006 0.0062
Schistosoma mansoni ryanodine receptor related 0.0039 0.0358 0.0437
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0338 0.0411
Schistosoma mansoni nAChR subunit 0.0062 0.0681 0.0852
Echinococcus granulosus transient receptor potential cation channel 0.0039 0.0358 0.0378
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0614 0.0597
Schistosoma mansoni lamin 0.0067 0.0753 0.0944
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.008 0.0936 0.118
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0061 0.0668 0.0652
Leishmania major alpha tubulin 0.021 0.2767 0.3506
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0972 0.2548
Echinococcus granulosus tubulin alpha chain 0.021 0.2767 0.3054
Brugia malayi Tubulin alpha-2 chain 0.021 0.2767 0.4056
Schistosoma mansoni growth hormone secretagogue receptor 0.0061 0.0668 0.0835
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0127 0.1601 0.1758
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0092 0.0195
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0039 0.0358 0.0378
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0092 0.0116
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0138 0.0083
Loa Loa (eye worm) hypothetical protein 0.0065 0.0735 0.0718
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0036 0.0318 0.03
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0039 0.0358 0.0378
Entamoeba histolytica phosphoinositide kinase, putative 0.0014 0.0018 0.0047
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0127 0.1601 0.1758
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0032 0.0268 0.0278
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0035 0.0305 0.0286
Toxoplasma gondii exonuclease III APE 0.0024 0.0157 0.0368
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0039 0.0358 0.0378
Loa Loa (eye worm) hypothetical protein 0.0061 0.0668 0.0652
Loa Loa (eye worm) hypothetical protein 0.008 0.0936 0.092
Echinococcus granulosus glycine receptor subunit alpha 1 0.0127 0.1601 0.1758
Schistosoma mansoni hypothetical protein 0.0568 0.7805 1
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0066 0.0743 0.1911
Echinococcus granulosus neuropeptide receptor 0.0061 0.0668 0.0722
Loa Loa (eye worm) calcium channel 0.0039 0.0358 0.0341
Onchocerca volvulus 0.0061 0.0668 0.0844
Loa Loa (eye worm) hypothetical protein 0.0127 0.1601 0.1586
Loa Loa (eye worm) hypothetical protein 0.0198 0.2597 0.2584
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0127 0.1601 0.1758
Loa Loa (eye worm) intermediate filament protein 0.0067 0.0753 0.0736
Echinococcus multilocularis shaker cognate 0.0039 0.0358 0.0378
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0035 0.0305 0.0253
Mycobacterium ulcerans putative regulatory protein 0.0023 0.0144 0.0089
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.006 0.0659 0.0643
Brugia malayi Cytochrome P450 family protein 0.0072 0.0832 0.12
Brugia malayi olfactory channel protein osm-9 0.0039 0.0358 0.0501
Onchocerca volvulus 0.0061 0.0668 0.0844
Schistosoma mansoni survival motor neuron protein 0.0026 0.0175 0.0202
Echinococcus multilocularis dihydrofolate reductase 0.0043 0.0426 0.0453
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0053 0.014
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0092 0.0157
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0039 0.0358 0.0896
Plasmodium falciparum ataxin-2 like protein, putative 0.0065 0.073 0.1876
Brugia malayi tubulin alpha chain - mouse 0.021 0.2767 0.4056

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.78 uM Inhibition of MAO-B in rat liver homogenate by spectrophotometry-based Holt method ChEMBL. 19945874
Ki (binding) = 3.7 uM Inhibition of MAO-A in rat liver homogenate by spectrophotometry-based Holt method ChEMBL. 19945874

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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