Detailed information for compound 109761

Basic information

Technical information
  • TDR Targets ID: 109761
  • Name: (4-tert-butylbenzyl)-methyl-(1-naphthylmethyl )amine
  • MW: 317.467 | Formula: C23H27N
  • H donors: 0 H acceptors: 0 LogP: 6.17 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(Cc1cccc2c1cccc2)Cc1ccc(cc1)C(C)(C)C
  • InChi: 1S/C23H27N/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20/h5-15H,16-17H2,1-4H3
  • InChiKey: ABJKWBDEJIDSJZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine
  • 1-(4-tert-butylphenyl)-N-methyl-N-(1-naphthylmethyl)methanamine
  • 1-(4-tert-butylphenyl)-N-methyl-N-(1-naphthalenylmethyl)methanamine
  • 101828-21-1
  • AIDS-008659
  • AIDS008659
  • Butenafina [INN-Spanish]
  • Butenafine
  • Butenafine HCL
  • Butenafine [INN]
  • Butenafine hydrochloride
  • Butenafinum [INN-Latin]
  • C08067
  • clazuril
  • DivK1c_007016
  • KBio1_001960
  • KBio2_002033
  • KBio2_004601
  • KBio2_007169
  • KBioSS_002033
  • KS-1035
  • N-(p-tert-Butylbenzyl)-N-methyl-1-naphthalenemethylamine
  • N-p-tert-Butylbenzyl-N-methyl-1-naphthalenemethylamine
  • NCGC00159511-02
  • NCGC00159511-03
  • SpecPlus_000920
  • Spectrum_001553

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens sigma non-opioid intracellular receptor 1 Starlite/ChEMBL No references
Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Starlite/ChEMBL No references
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 4 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens acetylcholinesterase (Yt blood group) Starlite/ChEMBL No references
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 2 Starlite/ChEMBL No references
Homo sapiens adrenoceptor alpha 2A Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma congolense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131051 All targets in OG5_131051
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) carboxylesterase Get druggable targets OG5_126875 All targets in OG5_126875
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Candida albicans sterol C8-C7 isomerase Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Trypanosoma cruzi C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K01049 acetylcholinesterase [EC3.1.1.7], putative Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Trypanosoma brucei C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Leishmania donovani C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Echinococcus granulosus carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Acetylcholinesterase 1 precursor, putative Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Leishmania braziliensis C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) acetylcholinesterase 1 Get druggable targets OG5_126875 All targets in OG5_126875
Leishmania infantum C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Brugia malayi ERG2 and Sigma1 receptor like protein Get druggable targets OG5_131051 All targets in OG5_131051
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans sterol C8-C7 isomerase Get druggable targets OG5_131051 All targets in OG5_131051
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi cytochrome P450 cytochrome P450, family 2, subfamily D, polypeptide 6 497 aa 425 aa 32.0 %
Brugia malayi Carboxylesterase family protein acetylcholinesterase (Yt blood group) 614 aa 510 aa 26.5 %
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 4 630 aa 574 aa 31.5 %
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 2 617 aa 638 aa 32.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0089 0.024
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0027
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0089 0.0822
Giardia lamblia DINP protein human, muc B family 0.0057 0.0121 0.0686
Brugia malayi Steroid receptor seven-up type 2 0.006 0.0132 0.0531
Mycobacterium ulcerans diacylglycerol kinase 0.0105 0.0269 0.0326
Brugia malayi MH2 domain containing protein 0.0476 0.141 0.5701
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0129 0.0344 0.139
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.0132 0.0132
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0014 0.0036
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0089 0.0101
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trypanosoma cruzi heat shock protein 85, putative 0.0091 0.0227 0.0611
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0031 0.0041 0.0166
Loa Loa (eye worm) latrophilin receptor protein 2 0.019 0.0531 0.0645
Trypanosoma cruzi heat shock protein 90, putative 0.0091 0.0227 0.0611
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Schistosoma mansoni sodium/chloride dependent transporter 0.0182 0.0508 0.0507
Trichomonas vaginalis helicase, putative 0.0052 0.0106 0.0375
Echinococcus granulosus TGF beta signal transducer SmadC 0.0032 0.0046 0.0046
Brugia malayi Phosphoglycerate kinase 0.0166 0.0458 0.185
Echinococcus multilocularis caspase 0.0026 0.0026 0.0026
Echinococcus multilocularis GPCR, family 2 0.019 0.0531 0.0531
Brugia malayi MH1 domain containing protein 0.0018 0.0001 0.0004
Mycobacterium tuberculosis Conserved protein 0.2696 0.824 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0117 0.0532
Trichomonas vaginalis heat shock protein, putative 0.0095 0.0239 0.0915
Schistosoma mansoni smad1 5 8 and 0.0032 0.0046 0.0046
Schistosoma mansoni terminal deoxycytidyl transferase 0.0057 0.0121 0.012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0221 0.0221
Loa Loa (eye worm) steroid hormone receptor 0.006 0.0132 0.016
Mycobacterium tuberculosis Probable two component sensor kinase 0.0042 0.0076 0.0065
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Schistosoma mansoni ferritin light chain 0.0025 0.0023 0.0022
Brugia malayi ImpB/MucB/SamB family protein 0.0107 0.0275 0.1109
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0076 0.0346
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0031
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0089 0.0239
Brugia malayi nuclear receptor RXR 0.0032 0.0044 0.0177
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0388 0.1139 0.1139
Schistosoma mansoni diacylglycerol kinase theta 0.0105 0.0269 0.0269
Onchocerca volvulus 0.0065 0.0145 0.0932
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0041 0.0041
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.006 0.0187
Schistosoma mansoni heat shock protein 0.0134 0.0357 0.0357
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0221 0.0268
Brugia malayi hypothetical protein 0.0247 0.0707 0.2857
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Trichomonas vaginalis glutaminase, putative 0.0821 0.2474 1
Trypanosoma brucei ISWI complex protein 0.0024 0.002 0.0054
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0117 0.0117
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0601 0.1795 0.7256
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0096 0.0095
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.006 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Leishmania major DNA topoisomerase 1A 0.0051 0.0103 0.0275
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0031 0.0041 0.0041
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0182 0.0508 0.0507
Echinococcus multilocularis mothers against decapentaplegic 5 0.0032 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.0319 0.0928 0.0928
Entamoeba histolytica DNA topoisomerase III, putative 0.0051 0.0103 0.0118
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0042 0.0076 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.006 0.0132 0.016
Trichomonas vaginalis bmru protein, putative 0.0105 0.0269 0.1038
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-40 0.006 0.0132 0.0531
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.006 0.016
Loa Loa (eye worm) hypothetical protein 0.0052 0.0107 0.013
Brugia malayi nuclear hormone receptor 0.006 0.0132 0.0531
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0031 0.0041 0.0041
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0317
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.006 0.0132 0.0131
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0117 0.0142
Schistosoma mansoni smad 0.0032 0.0046 0.0046
Leishmania major hypothetical protein, conserved 0.0105 0.0269 0.0725
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0458 0.1233
Entamoeba histolytica hypothetical protein 0.0069 0.0158 0.0186
Echinococcus multilocularis smad 0.0032 0.0046 0.0046
Echinococcus granulosus mixed lineage leukemia protein mll 0.0059 0.0128 0.0128
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0128 0.0345
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0042 0.0076 0.0205
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0145 0.1116
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Brugia malayi Importin beta-1 subunit 0.003 0.0038 0.0153
Loa Loa (eye worm) hypothetical protein 0.0105 0.0269 0.0327
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Brugia malayi photoreceptor-specific nuclear receptor 0.006 0.0132 0.0531
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0388 0.1139 0.1139
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.019 0.0531 0.0531
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0025 0.0025
Brugia malayi hypothetical protein 0.0028 0.0034 0.0135
Brugia malayi jmjC domain containing protein 0.004 0.007 0.028
Echinococcus granulosus neuropeptide s receptor 0.0943 0.2847 0.2847
Schistosoma mansoni alpha-glucosidase 0.0143 0.0387 0.0387
Echinococcus granulosus FTZ F1 alpha 0.006 0.0132 0.0132
Brugia malayi ecdysteroid receptor 0.006 0.0132 0.0531
Brugia malayi intermediate filament protein 0.0053 0.011 0.0443
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0007
Echinococcus multilocularis rho GTPase activating protein 20 0.0051 0.0103 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0032 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0158 0.0588
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.0132 0.0531
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0025 0.0025
Echinococcus granulosus fetal alzheimer antigen falz 0.0035 0.0054 0.0054
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0089 0.0358
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Loa Loa (eye worm) hypothetical protein 0.0042 0.0076 0.0093
Plasmodium falciparum heat shock protein 90, putative 0.0199 0.0559 0.2545
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0055 0.0116 0.0116
Echinococcus granulosus serotonin transporter 0.0182 0.0508 0.0508
Leishmania major DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0042 0.0076 0.0092
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.0458 0.0556
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0042 0.0076 0.0092
Brugia malayi latrophilin 2 splice variant baaae 0.0411 0.121 0.4891
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0034 0.0152
Brugia malayi diacylglycerol kinase 0.0105 0.0269 0.1087
Mycobacterium ulcerans heat shock protein 90 0.0095 0.0239 0.0289
Schistosoma mansoni alpha-glucosidase 0.0143 0.0387 0.0387
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0042 0.0076 0.0205
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0117 0.0315
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Trypanosoma cruzi diacylglycerol kinase, putative 0.0105 0.0269 0.0725
Schistosoma mansoni apoptosis regulator bax 0.0081 0.0196 0.0196
Echinococcus granulosus bloom syndrome protein 0.0044 0.0082 0.0082
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0186 0.0519 0.0519
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Schistosoma mansoni Tr4/Tr2 (homologue) 0.006 0.0132 0.0131
Plasmodium vivax phosphoglycerate kinase, putative 0.0166 0.0458 0.2084
Echinococcus granulosus phosphoglycerate kinase 1 0.0166 0.0458 0.0458
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0044 0.0177
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Leishmania major phosphoglycerate kinase B, cytosolic 0.0166 0.0458 0.1233
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0019 0.0006 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.0132 0.0531
Trichomonas vaginalis DNA topoisomerase II, putative 0.0186 0.0519 0.2053
Leishmania major DNA polymerase eta, putative 0.0068 0.0154 0.0415
Entamoeba histolytica hypothetical protein 0.0176 0.0489 0.0587
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.006 0.0132 0.016
Plasmodium vivax metacaspase 1, putative 0.0026 0.0026 0.0117
Echinococcus multilocularis dnaJ subfamily B 0.3268 1 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0028 0.0034 0.0135
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0014 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-1 0.006 0.0132 0.0531
Loa Loa (eye worm) hypothetical protein 0.0037 0.0061 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0317
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0129 0.0344 0.0411
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Brugia malayi PHD-finger family protein 0.0024 0.0021 0.0083
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0002 0.0016
Echinococcus multilocularis heat shock protein 90 0.0091 0.0227 0.0227
Trypanosoma brucei heat shock protein 90, putative 0.0134 0.0357 0.0962
Schistosoma mansoni myelin transcription factor 1 myt1 0.0109 0.0281 0.028
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0047 0.0089 0.0081
Loa Loa (eye worm) MBCTL1 0.0109 0.0281 0.0341
Echinococcus granulosus thyroid hormone receptor alpha 0.0028 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0047 0.0089 0.0089
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Trypanosoma cruzi DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Loa Loa (eye worm) nuclear factor I 0.0018 0.0001 0.0002
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Trypanosoma cruzi DNA polymerase eta, putative 0.0068 0.0154 0.0415
Plasmodium falciparum zinc finger protein, putative 0.0029 0.0035 0.0159
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0579 0.1728 0.4656
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0166
Onchocerca volvulus 0.0046 0.0089 0.0532
Schistosoma mansoni transcription factor LCR-F1 0.0176 0.0489 0.0489
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0089 0.0239
Schistosoma mansoni RAR-like nuclear receptor 0.006 0.0132 0.0131
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Loa Loa (eye worm) apoptosis regulator protein 0.0081 0.0196 0.0238
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0103 0.0276
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0038 0.0102
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0089 0.0685
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0166
Giardia lamblia Grp94/Hsp90 0.0095 0.0239 0.1358
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Echinococcus granulosus mothers against decapentaplegic 5 0.0032 0.0046 0.0046
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0035 0.0054 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.006 0.0132 0.016
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Mycobacterium ulcerans two component regulator - sensor kinase 0.0042 0.0076 0.0092
Trypanosoma cruzi metacaspase, putative 0.0026 0.0026 0.0069
Echinococcus granulosus dna polymerase kappa 0.0057 0.0121 0.0121
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.007 0.0084
Echinococcus multilocularis serotonin transporter 0.0182 0.0508 0.0508
Schistosoma mansoni hypothetical protein 0.019 0.0531 0.0531
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0105 0.0269 0.0269
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0445 0.1314 0.5313
Brugia malayi MH2 domain containing protein 0.0032 0.0046 0.0184
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0008 0.001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0601 0.1795 0.2179
Brugia malayi hypothetical protein 0.0032 0.0044 0.0177
Loa Loa (eye worm) hypothetical protein 0.004 0.0069 0.0083
Schistosoma mansoni hypothetical protein 0.002 0.0008 0.0008
Trypanosoma brucei heat shock protein 90, putative 0.0134 0.0357 0.0962
Schistosoma mansoni hypothetical protein 0.0411 0.121 0.121
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0089 0.0108
Echinococcus multilocularis dna polymerase kappa 0.0057 0.0121 0.0121
Brugia malayi jmjC domain containing protein 0.004 0.007 0.028
Schistosoma mansoni endoplasmin 0.0134 0.0357 0.0357
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0019 0.005
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Echinococcus granulosus Diacylglycerol kinase zeta 0.0105 0.0269 0.0269
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0089 0.0108
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0034 0.0258
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0034 0.0033
Schistosoma mansoni ferritin 0.0025 0.0023 0.0022
Trichomonas vaginalis heat shock protein, putative 0.0095 0.0239 0.0915
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Schistosoma mansoni DNA helicase recq1 0.0018 0.0002 0.0002
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0054 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.002 0.0026
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0057 0.0121 0.0121
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0096 0.024 0.024
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0089 0.0822
Schistosoma mansoni hypothetical protein 0.019 0.0531 0.0531
Schistosoma mansoni hypothetical protein 0.0105 0.0269 0.0269
Trypanosoma brucei Metacaspase-4 0.0026 0.0026 0.0069
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0146 0.0391
Brugia malayi steroid hormone receptor 0.006 0.0132 0.0531
Brugia malayi Nuclear hormone receptor-like 1 0.006 0.0132 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0158 0.0588
Onchocerca volvulus 0.0479 0.1419 1
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.006 0.0132 0.016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Plasmodium vivax heat shock protein, putative 0.0199 0.0559 0.2545
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0146 0.0391
Schistosoma mansoni nuclear receptor nhr-48 0.0028 0.0034 0.0033
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0458 0.1233
Loa Loa (eye worm) intermediate filament protein 0.0053 0.011 0.0133
Echinococcus multilocularis geminin 0.0838 0.2523 0.2523
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0186 0.0519 0.3592
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.006 0.006
Echinococcus multilocularis transcription factor Dp 1 0.0075 0.0176 0.0176
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0042 0.0076 0.0065
Mycobacterium tuberculosis Diacylglycerol kinase 0.0105 0.0269 0.03
Loa Loa (eye worm) MH2 domain-containing protein 0.0476 0.141 0.1712
Treponema pallidum DNA topoisomerase I (topA) 0.0051 0.0103 0.0368
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0157 0.0157
Schistosoma mansoni thyroid hormone receptor 0.006 0.0132 0.0131
Toxoplasma gondii exonuclease III APE 0.0056 0.0117 0.09
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0121 0.0146
Leishmania major DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.006 0.006
Echinococcus multilocularis survival motor neuron protein 1 0.0474 0.1404 0.1404
Leishmania major phosphoglycerate kinase C, glycosomal 0.0166 0.0458 0.1233
Loa Loa (eye worm) hypothetical protein 0.0247 0.0707 0.0858
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0047 0.0089 0.024
Loa Loa (eye worm) transcription factor SMAD2 0.0476 0.141 0.1712
Echinococcus granulosus dna polymerase eta 0.0107 0.0275 0.0275
Toxoplasma gondii DNA methyltransferase 2, putative 0.0019 0.0006 0.004
Echinococcus multilocularis lamin 0.0053 0.011 0.011
Entamoeba histolytica hypothetical protein, conserved 0.2696 0.824 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0034 0.0034
Brugia malayi Cell death protein 3 precursor 0.0026 0.0026 0.0103
Loa Loa (eye worm) nuclear receptor NHR-67 0.0028 0.0034 0.0041
Brugia malayi RNA, U transporter 1 0.0085 0.0208 0.0838
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.006 0.016
Leishmania major GTP-binding protein, putative 0.0022 0.0014 0.0036
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0731 0.2195 0.2644
Loa Loa (eye worm) hypothetical protein 0.0166 0.0458 0.0556
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0026 0.0197
Brugia malayi nuclear hormone receptor 0.0028 0.0034 0.0135
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0089 0.0358
Schistosoma mansoni thyroid hormone receptor 0.006 0.0132 0.0131
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Toxoplasma gondii hypothetical protein 0.0197 0.0553 0.4264
Toxoplasma gondii Hsp90 domain-containing protein 0.0199 0.0559 0.4306
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0026 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0186 0.0519 0.2096
Leishmania major diacylglycerol kinase, putative 0.0105 0.0269 0.0725
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0127 0.0154
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Loa Loa (eye worm) hypothetical protein 0.0411 0.121 0.1469
Plasmodium falciparum diacylglycerol kinase, putative 0.0105 0.0269 0.1225
Giardia lamblia DNA topoisomerase III 0.0051 0.0103 0.0582
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0089 0.024
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0458 0.1233
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.006 0.0132 0.0131
Plasmodium vivax JmjC domain containing protein 0.004 0.007 0.0316
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0073 0.0171 0.0171
Echinococcus multilocularis phd:f box containing protein 0.004 0.007 0.007
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0172 0.0475 0.1281
Schistosoma mansoni DNA polymerase eta 0.0107 0.0275 0.0274
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0019 0.0016
Echinococcus granulosus snurportin 1 0.0319 0.0928 0.0928
Trichomonas vaginalis diacylglycerol kinase, putative 0.0105 0.0269 0.1038
Echinococcus granulosus polycomb protein SCMH1 0.0096 0.024 0.024
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0117 0.0665
Toxoplasma gondii hypothetical protein 0.0083 0.0201 0.1543
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0042 0.0076 0.0092
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0243 0.0983
Onchocerca volvulus Protein ultraspiracle homolog 0.006 0.0132 0.0836
Trypanosoma cruzi Heat shock protein 83, putative 0.0134 0.0357 0.0962
Trypanosoma brucei DNA polymerase eta, putative 0.0107 0.0275 0.0739
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.006 0.0132 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-49 0.006 0.0132 0.0531
Brugia malayi tailless protein 0.0028 0.0034 0.0135
Onchocerca volvulus 0.0182 0.0508 0.3512
Echinococcus multilocularis lamin dm0 0.0053 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0027
Echinococcus multilocularis caspase 8 0.0026 0.0026 0.0026
Leishmania major metacaspase, putative 0.0026 0.0026 0.0069
Schistosoma mansoni lamin 0.0053 0.011 0.011
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0081 0.0196 0.0196
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Brugia malayi Hsp90 protein 0.0057 0.0122 0.0492
Echinococcus granulosus heat shock protein 0.0134 0.0357 0.0357
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0196 0.0196
Schistosoma mansoni importin beta-1 0.003 0.0038 0.0038
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0051 0.0103 0.0103
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.021 0.0591 0.1593
Echinococcus granulosus retinoic acid receptor rxr beta a 0.006 0.0132 0.0132
Echinococcus multilocularis cpg binding protein 0.0277 0.0799 0.0799
Echinococcus granulosus survival motor neuron protein 1 0.0474 0.1404 0.1404
Echinococcus multilocularis transcription factor btf3 0.0069 0.0158 0.0158
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0344 0.0926
Loa Loa (eye worm) heat shock protein 90 0.0134 0.0357 0.0434
Trypanosoma brucei metacaspase MCA3 0.0026 0.0026 0.0069
Entamoeba histolytica DNA topoisomerase II, putative 0.0186 0.0519 0.0623
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1224 0.3711 1
Plasmodium falciparum DNA topoisomerase 2 0.0186 0.0519 0.2362
Onchocerca volvulus 0.0096 0.024 0.1608
Loa Loa (eye worm) histone methyltransferase 0.0073 0.0171 0.0208
Leishmania major hypothetical protein, conserved 0.0105 0.0269 0.0725
Plasmodium vivax heat shock protein 90, putative 0.0057 0.0122 0.0555
Onchocerca volvulus Huntingtin homolog 0.0247 0.0707 0.4932
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Plasmodium falciparum DNA topoisomerase 3, putative 0.0051 0.0103 0.0466
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0054 0.0053
Mycobacterium ulcerans hypothetical protein 0.0645 0.1929 0.2341
Trypanosoma brucei C-8 sterol isomerase, putative 0.0445 0.1314 0.3541
Mycobacterium ulcerans phosphoglycerate kinase 0.0166 0.0458 0.0555
Echinococcus multilocularis neuropeptide s receptor 0.0943 0.2847 0.2847
Trichomonas vaginalis sensor histidine kinase, putative 0.0042 0.0076 0.0254
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.006 0.0187
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0041 0.0041
Leishmania major hypothetical protein, conserved 0.004 0.007 0.0187
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0198 0.0198
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0026 0.0026 0.0026
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0166 0.0458 0.053
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1224 0.3711 1
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Schistosoma mansoni ferritin 0.0025 0.0023 0.0022
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0042 0.0076 0.0254
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0117 0.0532
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trichomonas vaginalis receptor histidine kinase, putative 0.0042 0.0076 0.0254
Loa Loa (eye worm) hypothetical protein 0.0135 0.0362 0.044
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trypanosoma cruzi DNA topoisomerase II, putative 0.0135 0.0362 0.0976
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0134 0.036
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.019 0.0531 0.0531
Echinococcus multilocularis snurportin 1 0.0319 0.0928 0.0928
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0105 0.0269 0.0269
Chlamydia trachomatis DNA gyrase subunit B 0.0731 0.2195 1
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0051 0.0103 0.0102
Toxoplasma gondii NAC domain-containing protein 0.0069 0.0158 0.1218
Brugia malayi hypothetical protein 0.0474 0.1404 0.5675
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0057 0.0121 0.0325
Loa Loa (eye worm) serotonin transporter b 0.0182 0.0508 0.0616
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0082 0.0082
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0042 0.0076 0.0254
Echinococcus multilocularis JmjC domain containing protein 4 0.004 0.007 0.007
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0081 0.0196 0.0196
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.003
Schistosoma mansoni jumonji domain containing protein 0.004 0.007 0.0069
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0051 0.0103 0.0275
Plasmodium falciparum heat shock protein 90 0.0134 0.0357 0.1627
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trypanosoma brucei developmentally regulated phosphoprotein 0.0042 0.0076 0.0205
Echinococcus granulosus ferritin 0.0025 0.0023 0.0023
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0089 0.0685
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0051 0.0103 0.036
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0006 0.0024
Onchocerca volvulus 0.0105 0.0269 0.1815
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.002 0.0026
Onchocerca volvulus 0.0028 0.0034 0.0138
Echinococcus multilocularis heat shock protein 0.0134 0.0357 0.0357
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0042 0.0076 0.0205
Brugia malayi Nuclear hormone receptor family member nhr-3 0.006 0.0132 0.0531
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0019 0.005
Trypanosoma cruzi Sphingosine kinase 0.0105 0.0269 0.0725
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0047 0.0089 0.0405
Onchocerca volvulus 0.0038 0.0062 0.0339
Treponema pallidum fructose-bisphosphate aldolase 0.0588 0.1756 0.7981
Loa Loa (eye worm) hypothetical protein 0.019 0.0531 0.0645
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.006 0.0073
Mycobacterium tuberculosis Conserved hypothetical protein 0.0057 0.0121 0.012
Giardia lamblia Fructose-bisphosphate aldolase 0.0588 0.1756 1
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0019 0.0021
Onchocerca volvulus 0.0031 0.0041 0.0193
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0089 0.0108
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0002 0.0002
Brugia malayi MH1 domain containing protein 0.0032 0.0046 0.0184
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.006 0.0458
Loa Loa (eye worm) hypothetical protein 0.0081 0.0196 0.0238
Echinococcus granulosus Smad4 0.0032 0.0046 0.0046
Leishmania major cathepsin L-like protease 0.0065 0.0146 0.0391
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.006 0.0132 0.0836
Plasmodium vivax diacylglycerol kinase, putative 0.0105 0.0269 0.1225
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0287 0.083 1
Echinococcus multilocularis lysine specific demethylase 6a 0.004 0.007 0.007
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0158 0.0426
Trichomonas vaginalis endoplasmin, putative 0.0096 0.0241 0.0922
Echinococcus granulosus jumonji domain containing protein 0.004 0.0068 0.0068
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0105 0.0269 0.0725
Brugia malayi HSF-type DNA-binding domain containing protein 0.0098 0.0248 0.1003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.007 0.0187
Loa Loa (eye worm) hypothetical protein 0.0107 0.0275 0.0333
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0019 0.0006 0.0005
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.011 0.0443
Schistosoma mansoni nuclear receptor 0.0028 0.0034 0.0033
Echinococcus multilocularis muscleblind protein 0.0152 0.0413 0.0413
Schistosoma mansoni diacylglycerol kinase theta 0.0105 0.0269 0.0269
Trichomonas vaginalis diacylglycerol kinase, putative 0.0105 0.0269 0.1038
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0158 0.0588
Echinococcus multilocularis sphingosine kinase 1 0.2696 0.824 0.824
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0042 0.0076 0.0346
Chlamydia trachomatis DNA topoisomerase I 0.0051 0.0103 0.0284
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0041 0.0041
Echinococcus multilocularis carboxylesterase 5A 0.0082 0.0198 0.0198
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0357 0.0962
Onchocerca volvulus Bile acid receptor homolog 0.006 0.0132 0.0836
Mycobacterium tuberculosis Conserved protein 0.0042 0.0076 0.0065
Echinococcus multilocularis jumonji domain containing 1A 0.004 0.007 0.007
Brugia malayi nuclear receptor NHR-88 0.006 0.0132 0.0531
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0057 0.0122 0.0767
Plasmodium falciparum transporter, putative 0.0031 0.0041 0.0187
Echinococcus multilocularis lysine specific demethylase 5A 0.015 0.0409 0.0409
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0051 0.0103 0.0788
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0129 0.0344 0.0344
Schistosoma mansoni sex comb on midleg homolog 0.0096 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0024 0.0021 0.0025
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.0034 0.0034
Brugia malayi Bromodomain containing protein 0.0086 0.0212 0.0855
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0084
Schistosoma mansoni myst-related protein 0.0029 0.0035 0.0035
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0002 0.0009
Trypanosoma cruzi DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.006 0.0132 0.0132
Leishmania major basic transcription factor 3a, putative 0.0069 0.0158 0.0426
Leishmania major diacylglycerol kinase-like protein 0.0105 0.0269 0.0725
Loa Loa (eye worm) hypothetical protein 0.0152 0.0413 0.0501
Echinococcus granulosus SAM and MBT domain containing protein 0.0096 0.024 0.024
Trypanosoma cruzi DNA polymerase eta, putative 0.0107 0.0275 0.0739
Brugia malayi nuclear receptor NHR-67 0.0028 0.0034 0.0135
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0139 0.0169
Brugia malayi hypothetical protein 0.0176 0.0489 0.1976
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0028 0.0034 0.0034
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0081 0.0196 0.0792
Brugia malayi heat shock protein 90 0.0134 0.0357 0.1443
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.0044 0.0054
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0588 0.1756 0.2126
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0057 0.0121 0.0121
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0014 0.0014
Chlamydia trachomatis DNA gyrase subunit B 0.0486 0.1442 0.6503
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0002 0.0008
Schistosoma mansoni pyruvate dehydrogenase 0.0042 0.0076 0.0076
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0042 0.0076 0.0092
Treponema pallidum heat shock protein 90 0.0095 0.0239 0.0995
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0117 0.0315
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.0166 0.0166
Trypanosoma cruzi Sphingosine kinase 0.0105 0.0269 0.0725
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0028 0.0034 0.0041
Schistosoma mansoni smad1 5 8 and 0.0032 0.0046 0.0046
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0121 0.0325
Toxoplasma gondii histone lysine demethylase JMJD6a 0.004 0.007 0.0534
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0105 0.0269 0.0725
Schistosoma mansoni bromodomain containing protein 0.0075 0.0177 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.006 0.0132 0.016
Echinococcus granulosus acetylcholinesterase 0.0082 0.0198 0.0198
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0109 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Schistosoma mansoni jumonji/arid domain-containing protein 0.0165 0.0455 0.0455
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0134 0.036
Mycobacterium ulcerans putative regultory protein 0.0042 0.0076 0.0092
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0117 0.0315
Plasmodium falciparum importin beta, putative 0.003 0.0038 0.0172
Schistosoma mansoni sphingoid long chain base kinase 0.2696 0.824 0.824
Brugia malayi Carboxylesterase family protein 0.0082 0.0198 0.0799
Schistosoma mansoni hypothetical protein 0.019 0.0531 0.0531
Echinococcus granulosus endoplasmin 0.0095 0.0239 0.0239
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0053 0.0037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0002
Echinococcus multilocularis SAM and MBT domain containing protein 0.0096 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Loa Loa (eye worm) hypothetical protein 0.0046 0.0089 0.0108
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0057 0.0122 0.0122
Echinococcus granulosus jumonji domain containing 1A 0.004 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0105 0.0269 0.1038
Schistosoma mansoni phosphatidylserine receptor 0.004 0.007 0.0069
Brugia malayi DNA topoisomerase III beta-1 0.0051 0.0103 0.0413
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0041 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Brugia malayi isocitrate dehydrogenase 0.0047 0.0089 0.0359
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0357 0.0962
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0002 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0002 0.0002
Toxoplasma gondii DNA topoisomerase 2, putative 0.0186 0.0519 0.3997
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0221 0.0221
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Entamoeba histolytica hypothetical protein 0.0176 0.0489 0.0587
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0026 0.0026
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0019 0.005
Schistosoma mansoni smad1 5 8 and 0.0032 0.0046 0.0046
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0317
Brugia malayi hypothetical protein 0.0028 0.0034 0.0135
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0145 0.0145
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0041 0.0041
Plasmodium falciparum phosphoglycerate kinase 0.0166 0.0458 0.2084
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Schistosoma mansoni Smad4 0.0032 0.0046 0.0046
Brugia malayi Muscleblind-like protein 0.0152 0.0413 0.1668
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0035 0.0054 0.0054
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0089 0.0108
Brugia malayi diacylglycerol kinase 0.0105 0.0269 0.1087
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0026 0.0026 0.0103
Loa Loa (eye worm) hypothetical protein 0.0105 0.0269 0.0327
Toxoplasma gondii heat shock protein 75, putative 0.0057 0.0122 0.0938
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0209 0.059 0.059
Trypanosoma brucei heat shock protein 84, putative 0.0057 0.0122 0.0328
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0139 0.0562
Giardia lamblia Heat shock protein HSP 90-alpha 0.0091 0.0227 0.1292
Trichomonas vaginalis bmru protein, putative 0.0105 0.0269 0.1038
Loa Loa (eye worm) hypothetical protein 0.0046 0.0089 0.0108
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.006 0.0132 0.0132
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0057 0.0121 0.0147
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0731 0.2195 1
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0053 0.0239
Brugia malayi GRF zinc finger family protein 0.0051 0.0103 0.0413
Loa Loa (eye worm) hypothetical protein 0.0182 0.0508 0.0616
Brugia malayi RNA binding protein 0.0063 0.0139 0.0562
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0042 0.0076 0.0247
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.007 0.0084
Schistosoma mansoni SET domain protein 0.0022 0.0014 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0089 0.0108
Brugia malayi Endoplasmin precursor 0.0134 0.0357 0.1443
Echinococcus granulosus smad 0.0032 0.0046 0.0046
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.006 0.0132 0.0132
Loa Loa (eye worm) glutaminase 0.0821 0.2474 0.3002
Brugia malayi orphan nuclear receptor NR2E1 0.0028 0.0034 0.0135
Leishmania major cathepsin L-like protease 0.0065 0.0146 0.0391
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0022 0.0059
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0146 0.0391
Toxoplasma gondii diacylglycerol kinase, putative 0.0105 0.0269 0.2073
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0026 0.0026 0.0026
Onchocerca volvulus Huntingtin homolog 0.0247 0.0707 0.4932
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trypanosoma cruzi metacaspase, putative 0.0026 0.0026 0.0069
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0083 0.0201 0.0912
Onchocerca volvulus 0.0262 0.0753 0.5258
Trichomonas vaginalis ferritin, putative 0.0025 0.0023 0.0035
Loa Loa (eye worm) diacylglycerol kinase 2 0.0105 0.0269 0.0327
Entamoeba histolytica deoxycytidyl transferase, putative 0.0057 0.0121 0.014
Loa Loa (eye worm) hypothetical protein 0.2696 0.824 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0014 0.0036
Loa Loa (eye worm) hypothetical protein 0.003 0.0038 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Leishmania major heat shock protein, putative 0.0057 0.0122 0.0328
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0042 0.0076 0.0092
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0042 0.0076 0.0585
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.004 0.007 0.0187
Leishmania major DNA topoisomerase ii 0.0135 0.0362 0.0976
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Brugia malayi hypothetical protein 0.0031 0.0041 0.0166
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0105 0.0269 0.2073
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0158 0.0426
Loa Loa (eye worm) acetylcholinesterase 1 0.0082 0.0198 0.024
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0042 0.0076 0.0065
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.0458 0.0458
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0034 0.0034
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0089 0.0089
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0057 0.0121 0.012
Loa Loa (eye worm) hypothetical protein 0.0098 0.0248 0.0302
Echinococcus multilocularis tumor protein p63 0.0332 0.0967 0.0967
Entamoeba histolytica heat shock transcription factor, putative 0.0098 0.0248 0.0295
Brugia malayi Carboxylesterase family protein 0.0082 0.0198 0.0799
Trichomonas vaginalis heat shock protein, putative 0.0091 0.0227 0.0867
Brugia malayi CXXC zinc finger family protein 0.0262 0.0753 0.3042
Loa Loa (eye worm) glutaminase 2 0.0821 0.2474 0.3002
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Schistosoma mansoni caspase-3 (C14 family) 0.0026 0.0026 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0041 0.0187
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0053 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Brugia malayi Pre-SET motif family protein 0.0421 0.1242 0.5018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.006 0.0132 0.0531
Echinococcus multilocularis histone acetyltransferase MYST2 0.0109 0.0281 0.0281
Brugia malayi Calcitonin receptor-like protein seb-1 0.0601 0.1795 0.7256
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0019 0.0006 0.0024
Plasmodium falciparum heat shock protein 90, putative 0.0053 0.011 0.0502
Leishmania major modification methylase-like protein 0.0019 0.0006 0.0014
Entamoeba histolytica DNA topoisomerase III, putative 0.0051 0.0103 0.0118
Schistosoma mansoni hypothetical protein 0.0592 0.1768 0.1767
Plasmodium vivax importin-beta 2, putative 0.003 0.0038 0.0172
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trypanosoma cruzi metacaspase, putative 0.0026 0.0026 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0059 0.0128 0.0128
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0089 0.0089
Schistosoma mansoni protein phosphatase 2C 0.004 0.007 0.0069
Mycobacterium ulcerans hypothetical protein 0.0046 0.0089 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.0132 0.0531
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0051 0.0103 0.0102
Plasmodium vivax amine transporter, putative 0.0031 0.0041 0.0187
Echinococcus granulosus transcription factor Dp 1 0.0075 0.0176 0.0176
Onchocerca volvulus 0.0051 0.0103 0.0628
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.006 0.0132 0.016
Loa Loa (eye worm) hypothetical protein 0.0182 0.0508 0.0616
Echinococcus granulosus ecdysone induced protein 78C 0.006 0.0132 0.0132
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.004 0.0068 0.0067
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0042 0.0076 0.0247
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.006 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.008 0.0192 0.0232
Leishmania major hypothetical protein, conserved 0.0042 0.0076 0.0205
Trypanosoma cruzi diacylglycerol kinase, putative 0.0105 0.0269 0.0725
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0038 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0179
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0095 0.0239 0.0643
Mycobacterium ulcerans DNA gyrase subunit B 0.0731 0.2195 0.2664
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0145 0.0145
Schistosoma mansoni ferritin light chain 0.0025 0.0023 0.0022
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.0044 0.0044
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0344 0.0926
Brugia malayi jmjC domain containing protein 0.0165 0.0455 0.1839
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0287 0.083 0.0983
Echinococcus granulosus transcription factor btf3 0.0069 0.0158 0.0158
Echinococcus granulosus carboxylesterase 5A 0.0082 0.0198 0.0198
Echinococcus multilocularis ferritin 0.0025 0.0023 0.0023
Brugia malayi mbt repeat family protein 0.0096 0.024 0.0969
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0042 0.0076 0.0065
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0053 0.0053
Echinococcus multilocularis ecdysone induced protein 78C 0.006 0.0132 0.0132
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0105 0.0269 0.1038
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0089 0.024
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.006 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0059 0.0128 0.0128
Echinococcus multilocularis polycomb protein SCMH1 0.0096 0.024 0.024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0026 0.0026 0.0026
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Trypanosoma brucei DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Brugia malayi ecdysone receptor 0.0028 0.0034 0.0135
Echinococcus multilocularis caspase 2 0.0026 0.0026 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Loa Loa (eye worm) mbt repeat family protein 0.0096 0.024 0.0291
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Schistosoma mansoni phd/f-box containing protein 0.004 0.007 0.0069
Plasmodium vivax diacylglycerol kinase, putative 0.0105 0.0269 0.1225
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0117 0.0435
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0458 0.1805
Schistosoma mansoni hypothetical protein 0.019 0.0531 0.0531
Schistosoma mansoni heat shock protein 0.0057 0.0122 0.0122
Trypanosoma brucei metacaspase 0.0026 0.0026 0.0069
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0034 0.0034
Trypanosoma brucei transcription factor BTF3, putative 0.0069 0.0158 0.0426
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Brugia malayi Disco-interacting protein 2 homolog 0.0038 0.0062 0.0249
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0019 0.0006 0.0006
Echinococcus granulosus caspase 8 0.0026 0.0026 0.0026
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0042 0.0076 0.0247
Echinococcus granulosus cpg binding protein 0.0277 0.0799 0.0799
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0166 0.0458 0.5387
Loa Loa (eye worm) hypothetical protein 0.0601 0.1795 0.2179
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0034 0.0258
Loa Loa (eye worm) hypothetical protein 0.0247 0.0707 0.0858
Loa Loa (eye worm) hypothetical protein 0.004 0.007 0.0084
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0129 0.0344 0.0417
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.004 0.007 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0098 0.0248 0.1667
Trichomonas vaginalis heat shock protein, putative 0.0053 0.011 0.0393
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0042 0.0076 0.0065
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0051 0.0103 0.0103
Schistosoma mansoni endoplasmin 0.0134 0.0357 0.0357
Schistosoma mansoni ran 0.0022 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0042 0.0076 0.0254
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0014 0.0104
Trypanosoma brucei DNA topoisomerase ii 0.0431 0.1272 0.3427
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0014 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0034 0.0034
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0117 0.042
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0034 0.0041
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0123 0.0123
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.0044 0.0044
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0034 0.0135
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0032 0.0046 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0051 0.0103 0.036
Trypanosoma brucei Heat shock protein 83, putative 0.0134 0.0357 0.0962
Echinococcus granulosus JmjC domain containing protein 4 0.004 0.007 0.007
Trypanosoma cruzi heat shock protein 90, putative 0.008 0.0193 0.0519
Schistosoma mansoni survival motor neuron protein 0.0097 0.0243 0.0243
Echinococcus multilocularis isocitrate dehydrogenase 0.0047 0.0089 0.0089
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0319 0.0928 0.1126
Leishmania major importin beta-1 subunit, putative 0.0024 0.0021 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Onchocerca volvulus 0.0028 0.0034 0.0138
Loa Loa (eye worm) solute carrier family 6 member 4 0.0182 0.0508 0.0616
Toxoplasma gondii hypothetical protein 0.0031 0.0041 0.0317
Schistosoma mansoni transcription factor btf3 0.0069 0.0158 0.0158
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0034 0.0135
Trichomonas vaginalis hypothetical protein 0.0028 0.0032 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0179
Echinococcus multilocularis dna polymerase eta 0.0107 0.0275 0.0275
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Entamoeba histolytica hypothetical protein 0.0176 0.0489 0.0587
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1597 0.4858 0.4858
Plasmodium falciparum diacylglycerol kinase, putative 0.0105 0.0269 0.1225
Schistosoma mansoni lamin 0.0053 0.011 0.011
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0057 0.0121 0.0435
Loa Loa (eye worm) MH1 domain-containing protein 0.0032 0.0046 0.0056
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0221 0.0893
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.004 0.007 0.0069
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0034 0.0033
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0105 0.0269 0.0269
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0081 0.0196 0.0196
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0172 0.0475 0.1281
Schistosoma mansoni zinc finger protein 0.0032 0.0045 0.0045
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0082 0.0279
Schistosoma mansoni myst-related protein 0.0029 0.0035 0.0035
Trypanosoma brucei diacylglycerol kinase, putative 0.0105 0.0269 0.0725
Echinococcus granulosus sphingosine kinase 1 0.2696 0.824 0.824
Plasmodium falciparum phd finger protein, putative 0.0028 0.0034 0.0152
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0129 0.0344 0.0926
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0105 0.0269 0.0269
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.019 0.0531 0.2146
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0042 0.0076 0.0665
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0172 0.0475 0.1281
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0002 0.0002
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0269 0.032
Schistosoma mansoni sex comb on midleg homolog 0.0096 0.024 0.024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0221 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-14 0.006 0.0132 0.0531
Loa Loa (eye worm) hypothetical protein 0.0046 0.0089 0.0108
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0059 0.0128 0.0128
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1224 0.3711 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0165 0.0455 0.0455
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0196 0.0196
Loa Loa (eye worm) CXXC zinc finger family protein 0.0262 0.0753 0.0914
Schistosoma mansoni apoferritin-2 0.0025 0.0023 0.0022
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0091 0.0227 0.0227
Brugia malayi MH1 domain containing protein 0.0032 0.0046 0.0184
Brugia malayi MH2 domain containing protein 0.0032 0.0046 0.0184
Loa Loa (eye worm) hypothetical protein 0.0049 0.0096 0.0116
Schistosoma mansoni hypothetical protein 0.0097 0.0243 0.0243
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0089 0.0089
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0082 0.0332
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Giardia lamblia Heat shock protein HSP 90-alpha 0.0134 0.0357 0.2033
Brugia malayi jmjC domain containing protein 0.004 0.007 0.028
Leishmania major mitochondrial DNA topoisomerase II 0.0431 0.1272 0.3427
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.011 0.0133
Brugia malayi F/Y-rich N-terminus family protein 0.0083 0.0203 0.0819
Echinococcus multilocularis zinc finger protein 0.0032 0.0045 0.0045
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0026 0.0197
Trichomonas vaginalis set domain proteins, putative 0.0478 0.1418 0.571
Giardia lamblia Pms1-like protein 0.0042 0.0076 0.0432
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0014 0.0036
Entamoeba histolytica heat shock protein 90, putative 0.0134 0.0357 0.0427
Schistosoma mansoni cpg binding protein 0.0277 0.0799 0.0798
Mycobacterium leprae Probable two-component sensor kinase 0.0042 0.0076 0.0665
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.0034 0.0034
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0489 0.145 0.145
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0047 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Loa Loa (eye worm) nuclear hormone receptor 0.0028 0.0034 0.0041
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.006 0.0132 0.0132
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0186 0.0519 0.3592
Trichomonas vaginalis heat shock protein, putative 0.0134 0.0357 0.1396
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Plasmodium falciparum endoplasmin, putative 0.0096 0.0241 0.1095
Echinococcus granulosus caspase 0.0026 0.0026 0.0026
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0095 0.0239 0.0995
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0117 0.0117
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0105 0.0269 0.0725
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0176 0.0489 0.0489
Leishmania major sphingosine kinase A, B, putative 0.0105 0.0269 0.0725
Leishmania major hypothetical protein, conserved 0.0025 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Schistosoma mansoni hypothetical protein 0.0081 0.0196 0.0196
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0081 0.0196 0.0238
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0731 0.2195 1
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.007 0.0084
Schistosoma mansoni ferritin 0.0025 0.0023 0.0022
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0041 0.0041
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0034 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0105 0.0269 0.0269
Mycobacterium ulcerans bacterioferritin BfrA 0.0025 0.0023 0.0027
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0042 0.0076 0.0065
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.0132 0.0132
Echinococcus granulosus Diacylglycerol kinase theta 0.0105 0.0269 0.0269
Schistosoma mansoni microtubule-associated protein tau 0.2778 0.8493 0.8493
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0089 0.0358
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0021 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0221 0.0221
Schistosoma mansoni DNA helicase recq5 0.0018 0.0002 0.0002
Brugia malayi Bromodomain containing protein 0.0031 0.0041 0.0164
Loa Loa (eye worm) MH2 domain-containing protein 0.0032 0.0046 0.0056
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0588 0.1756 0.2126
Brugia malayi Isocitrate dehydrogenase 0.0047 0.0089 0.0359
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0186 0.0519 0.2096
Loa Loa (eye worm) norepinephrine transporter 0.0182 0.0508 0.0616
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0042 0.0076 0.0092
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0051 0.0103 0.099
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0458 0.0457
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0051 0.0103 0.0368
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0431 0.1272 0.3427
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0431 0.1272 0.9803
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0117 0.0315
Echinococcus multilocularis importin subunit beta 1 0.003 0.0038 0.0038
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0135 0.0362 0.0976
Brugia malayi Probable DNA topoisomerase II 0.0186 0.0519 0.2096
Brugia malayi PHD-finger family protein 0.0028 0.0034 0.0135
Giardia lamblia Phosphoglycerate kinase 0.0166 0.0458 0.2605
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Echinococcus granulosus lysine specific demethylase 6a 0.004 0.007 0.007
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0458 0.0457
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.006 0.0132 0.0531
Echinococcus granulosus neuropeptide receptor A26 0.0943 0.2847 0.2847
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0032 0.0046 0.0046
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0186 0.0519 0.0519
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0023 0.0018 0.008
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0117 0.0435
Entamoeba histolytica hypothetical protein 0.0024 0.0021 0.0018
Echinococcus multilocularis musashi 0.0053 0.011 0.011
Schistosoma mansoni jumonji domain containing protein 0.019 0.0531 0.0531
Echinococcus multilocularis thyroid hormone receptor alpha 0.006 0.0132 0.0132
Echinococcus granulosus acetylcholinesterase 0.0082 0.0198 0.0198
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Schistosoma mansoni coup transcription factor 0.006 0.0132 0.0131
Giardia lamblia PHD finger protein 15 0.0028 0.0034 0.019
Echinococcus granulosus lysine specific demethylase 5A 0.0165 0.0455 0.0455
Echinococcus granulosus geminin 0.0838 0.2523 0.2523
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0121 0.0325
Plasmodium vivax basic transcription factor 3b, putative 0.0069 0.0158 0.072
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Schistosoma mansoni DNA topoisomerase II 0.0186 0.0519 0.0518
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.003
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0042 0.0076 0.0076
Schistosoma mansoni heat shock protein 0.0134 0.0357 0.0357
Chlamydia trachomatis phosphoglycerate kinase 0.0166 0.0458 0.1933
Schistosoma mansoni ferritin 0.0025 0.0023 0.0022
Mycobacterium ulcerans glutaminase 0.0821 0.2474 0.3002
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0106 0.0375
Loa Loa (eye worm) hypothetical protein 0.0182 0.0508 0.0616
Schistosoma mansoni hypothetical protein 0.0081 0.0196 0.0196
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.006 0.0132 0.016
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0032 0.0074
Onchocerca volvulus Ceramide kinase 1 homolog 0.0105 0.0269 0.1815
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0196 0.0196
Entamoeba histolytica transcription factor BTF3, putative 0.0069 0.0158 0.0186
Plasmodium vivax DNA topoisomerase II, putative 0.0186 0.0519 0.2362
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0458 0.0458
Schistosoma mansoni sodium-dependent amino acid transporter 0.0031 0.0041 0.0041
Schistosoma mansoni ran 0.0022 0.0014 0.0013
Trypanosoma cruzi heat shock protein 90, putative 0.0134 0.0357 0.0962
Entamoeba histolytica phosphoglycerate kinase, putative 0.0166 0.0458 0.0549
Toxoplasma gondii heat shock protein HSP90 0.0134 0.0357 0.2752
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0135 0.0362 0.0976
Trichomonas vaginalis heat shock protein, putative 0.0096 0.0241 0.0922
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0089 0.0081
Onchocerca volvulus 0.0031 0.0041 0.0193
Brugia malayi mbt repeat family protein 0.0096 0.024 0.0969
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0117 0.0136
Brugia malayi conserved hypotetical protein 0.0028 0.0034 0.0135
Schistosoma mansoni ap endonuclease 0.0056 0.0117 0.0117
Echinococcus granulosus tumor protein p63 0.0332 0.0967 0.0967
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0054 0.0054
Plasmodium vivax SET domain protein, putative 0.0065 0.0145 0.066
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0051 0.0103 0.0103
Loa Loa (eye worm) RNA binding protein 0.0063 0.0139 0.0169
Entamoeba histolytica heat shock protein 90, putative 0.0134 0.0357 0.0427
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.006 0.0066
Brugia malayi Smad1 0.0032 0.0046 0.0184
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0044 0.0044
Plasmodium falciparum metacaspase 1 0.0026 0.0026 0.0117
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0057 0.0121 0.012
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0082 0.0198 0.0198
Schistosoma mansoni steroid hormone receptor ad4bp 0.006 0.0132 0.0131
Brugia malayi Nuclear hormone receptor E75 0.0028 0.0034 0.0135
Leishmania major developmentally regulated phosphoprotein-like protein 0.0042 0.0076 0.0205
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.0034 0.0138
Echinococcus granulosus muscleblind protein 0.0152 0.0413 0.0413
Loa Loa (eye worm) Smad1 0.0032 0.0046 0.0056
Plasmodium falciparum DNA gyrase subunit B 0.0731 0.2195 1
Onchocerca volvulus Cell death protein 3 homolog 0.0026 0.0026 0.0083
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0413 0.0413
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0028 0.0034 0.0033
Toxoplasma gondii histone lysine methyltransferase SET1 0.0439 0.1297 1
Brugia malayi hypothetical protein 0.0025 0.0022 0.0089
Loa Loa (eye worm) hypothetical protein 0.0053 0.011 0.0133
Brugia malayi Eye-specific diacylglycerol kinase 0.0105 0.0269 0.1087
Entamoeba histolytica hypothetical protein 0.0029 0.0035 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.002 0.0026
Schistosoma mansoni hypothetical protein 0.0838 0.2523 0.2523
Trypanosoma brucei unspecified product 0.0057 0.0121 0.0325
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0221 0.0221
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Echinococcus granulosus peregrin 0.0031 0.0041 0.0041
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0031 0.0041 0.0041
Schistosoma mansoni retinoic acid receptor RXR 0.006 0.0132 0.0131
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0105 0.0269 0.0725
Echinococcus granulosus nuclear receptor 2DBD gamma 0.006 0.0132 0.0132
Mycobacterium leprae Probable two component sensor kinase MprB 0.0042 0.0076 0.0665
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0089 0.0101
Brugia malayi jmjC domain containing protein 0.0209 0.059 0.2384
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0044 0.0177
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0041 0.0041
Trypanosoma brucei glucosidase, putative 0.0037 0.006 0.016
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Brugia malayi TAR-binding protein 0.0063 0.0139 0.0562
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.022 0.022
Brugia malayi Nuclear hormone receptor family member nhr-41 0.006 0.0132 0.0531
Giardia lamblia DNA topoisomerase II 0.0144 0.0389 0.2212
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0021 0.0055
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0022 0.01
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0022 0.0169
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Echinococcus granulosus lamin dm0 0.0053 0.011 0.011
Leishmania major C-8 sterol isomerase-like protein 0.0445 0.1314 0.3541
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0066 0.0299
Entamoeba histolytica heat shock transcription factor, putative 0.0098 0.0248 0.0295
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0269 0.0725
Trichomonas vaginalis DNA polymerase eta, putative 0.0057 0.0121 0.0435
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0129 0.0344 0.0344
Brugia malayi nuclear hormone receptor family member odr-7 0.0028 0.0034 0.0135
Trichomonas vaginalis sphingosine kinase, putative 0.0105 0.0269 0.1038
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.006 0.0132 0.0132
Trypanosoma cruzi DNA topoisomerase II, putative 0.0135 0.0362 0.0976
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0269 0.032
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0055 0.0116 0.0116
Loa Loa (eye worm) ICD-1 protein 0.0069 0.0158 0.0192
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0146 0.0391
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0176 0.0489 0.0489
Schistosoma mansoni intermediate filament proteins 0.0053 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Treponema pallidum sodium- and chloride- dependent transporter 0.0182 0.0508 0.2233
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0082 0.0279
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Trypanosoma brucei unspecified product 0.0039 0.0067 0.0179
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.006 0.0066
Brugia malayi glutaminase DH11.1 0.0821 0.2474 1
Schistosoma mansoni cpg binding protein 0.0277 0.0799 0.0798
Echinococcus granulosus intermediate filament protein 0.0053 0.011 0.011
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0057 0.0122 0.0142
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0042 0.0076 0.0092
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0034 0.0041
Echinococcus granulosus DNA methyltransferase 2, putative 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0031
Loa Loa (eye worm) hypothetical protein 0.0105 0.0269 0.0327
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0186 0.0519 0.3592
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.006 0.016
Plasmodium falciparum JmjC domain-containing protein, putative 0.004 0.007 0.0316
Brugia malayi nuclear hormone receptor family member nhr-6 0.0028 0.0034 0.0135
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0038 0.0291
Loa Loa (eye worm) DNA topoisomerase III 0.0051 0.0103 0.0124
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Schistosoma mansoni ap endonuclease 0.0056 0.0117 0.0117
Echinococcus granulosus heat shock protein 90 0.0091 0.0227 0.0227
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0458 0.0458
Leishmania major DNA polymerase eta, putative 0.0107 0.0275 0.0739
Brugia malayi hypothetical protein 0.0105 0.0269 0.1087
Loa Loa (eye worm) isocitrate dehydrogenase 0.0047 0.0089 0.0108
Brugia malayi PHD-finger family protein 0.0037 0.0061 0.0246
Schistosoma mansoni cpg binding protein 0.0262 0.0753 0.0752
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0421 0.1242 0.1507
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0054
Loa Loa (eye worm) hypothetical protein 0.0227 0.0645 0.0783
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0176 0.0489 0.0489
Mycobacterium tuberculosis Conserved hypothetical protein 0.0645 0.1929 0.232
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0139 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0179
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0106 0.0375
Loa Loa (eye worm) ceramide kinase 0.0105 0.0269 0.0327
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0105 0.0269 0.2073
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Onchocerca volvulus 0.0049 0.0096 0.0578
Plasmodium falciparum amino acid transporter, putative 0.0031 0.0041 0.0187
Entamoeba histolytica heat shock transcription factor, putative 0.0098 0.0248 0.0295
Trypanosoma brucei Sphingosine kinase 0.0105 0.0269 0.0725
Leishmania major cathepsin L-like protease 0.0065 0.0146 0.0391
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0117 0.0115
Loa Loa (eye worm) jmjC domain-containing protein 0.0165 0.0455 0.0552
Brugia malayi Latrophilin receptor protein 2 0.019 0.0531 0.2146
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0057 0.0122 0.0122
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0579 0.1728 0.4656
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0096 0.024 0.1608
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0431 0.1272 0.3427
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0089 0.0239
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0089 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0588 0.1756 0.7084
Schistosoma mansoni nuclear hormone receptor 0.006 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0445 0.1314 0.1595
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.006 0.024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.006 0.0132 0.0131
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0105 0.0269 0.0327
Echinococcus granulosus microtubule associated protein 2 0.2778 0.8493 0.8493
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0109 0.0281 0.1134
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0172 0.0475 0.1281
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Plasmodium vivax DNA gyrase subunit B, putative 0.0731 0.2195 1
Echinococcus granulosus tar DNA binding protein 0.0063 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0121 0.0325
Schistosoma mansoni hypothetical protein 0.0081 0.0196 0.0196
Giardia lamblia DNA topoisomerase III 0.0051 0.0103 0.0582
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0026 0.0026
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0117 0.0472
Plasmodium vivax DNA topoisomerase 3, putative 0.0051 0.0103 0.0466
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0042 0.0076 0.0076
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0051 0.0103 0.0124
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0445 0.1314 0.3541
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Brugia malayi Bromodomain containing protein 0.0037 0.0061 0.0246
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0042 0.0076 0.0092
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0026 0.0197
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0022 0.01
Loa Loa (eye worm) hypothetical protein 0.0082 0.0198 0.024
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0051 0.0103 0.0275
Brugia malayi SET domain containing protein 0.0026 0.0028 0.011
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0081 0.0196 0.0196
Loa Loa (eye worm) carboxylesterase 0.0082 0.0198 0.024
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0022 0.0059
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0034 0.0033
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0042 0.0076 0.0585
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0014 0.0062
Leishmania major DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Schistosoma mansoni glutaminase 0.0821 0.2474 0.2473
Echinococcus multilocularis endoplasmin 0.0095 0.0239 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Plasmodium vivax heat shock protein 86, putative 0.0134 0.0357 0.1627
Toxoplasma gondii heat shock protein 90, putative 0.0134 0.0357 0.2752
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0042 0.0076 0.0665
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.0458 0.1852
Echinococcus multilocularis Smad4 0.0032 0.0046 0.0046
Echinococcus granulosus ceramide kinase 0.0105 0.0269 0.0269
Onchocerca volvulus 0.006 0.0132 0.0836
Treponema pallidum phosphoglycerate kinase 0.0166 0.0458 0.2003
Echinococcus multilocularis FTZ F1 alpha 0.006 0.0132 0.0132
Echinococcus granulosus disco interacting protein 2 0.004 0.0068 0.0068
Brugia malayi nuclear receptor RXR 0.0028 0.0034 0.0135
Brugia malayi Phosphoglycerate kinase 0.0061 0.0134 0.054
Onchocerca volvulus 0.0053 0.011 0.068
Loa Loa (eye worm) hypothetical protein 0.0069 0.0159 0.0193
Onchocerca volvulus 0.0053 0.011 0.068
Trypanosoma cruzi heat shock protein, putative 0.0057 0.0122 0.0328
Trypanosoma brucei DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Mycobacterium ulcerans bacterioferritin BfrB 0.0025 0.0023 0.0027
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0105 0.0269 0.1038
Brugia malayi Ceramide kinase 0.0105 0.0269 0.1087
Loa Loa (eye worm) hypothetical protein 0.0096 0.024 0.0291
Echinococcus multilocularis heat shock protein 90 0.0134 0.0357 0.0357
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0047 0.0089 0.0405
Schistosoma mansoni sphingosine kinase A B 0.2696 0.824 0.824
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.0034 0.0138
Mycobacterium ulcerans DNA topoisomerase I 0.0051 0.0103 0.0124
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.0054 0.0054
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0028 0.0034 0.0034
Toxoplasma gondii DNA topoisomerase family protein 0.0051 0.0103 0.0788
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0081 0.0196 0.0196
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0221 0.0221
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0117 0.042
Trypanosoma cruzi metacaspase, putative 0.0026 0.0026 0.0069
Trichomonas vaginalis receptor histidine kinase, putative 0.0042 0.0076 0.0254
Echinococcus granulosus GPCR family 2 0.019 0.0531 0.0531
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0014 0.0062
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.019 0.0531 0.0531
Trypanosoma brucei metacaspase 5, putative 0.0026 0.0026 0.0069
Mycobacterium ulcerans hypothetical protein 0.2696 0.824 1
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0042 0.0076 0.0076
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.006 0.0132 0.0132
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0022 0.01
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0287 0.083 0.1007
Echinococcus granulosus caspase 2 0.0026 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Onchocerca volvulus Alhambra homolog 0.0028 0.0034 0.0139
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0028 0.0034 0.0033
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Echinococcus multilocularis ceramide kinase 0.0105 0.0269 0.0269
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0458 0.1805
Echinococcus multilocularis nuclear receptor nhr 48 0.0028 0.0034 0.0034
Loa Loa (eye worm) TOPoisomerase family member 0.0186 0.0519 0.063
Onchocerca volvulus 0.0097 0.0243 0.1632
Echinococcus granulosus zinc finger protein 0.0032 0.0045 0.0045
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.0508 0.2051
Echinococcus multilocularis peregrin 0.0031 0.0041 0.0041
Brugia malayi kinase, mitochondrial precursor 0.0042 0.0076 0.0307
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0073 0.0171 0.0171
Schistosoma mansoni nuclear receptor 0.0028 0.0034 0.0033
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0002 0.0008
Trypanosoma cruzi heat shock protein 85, putative 0.0134 0.0357 0.0962
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0037 0.0284
Mycobacterium tuberculosis Possible two component sensor kinase 0.0042 0.0076 0.0065
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0042 0.0076 0.0254
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0196 0.0196
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.0166 0.0166
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0209 0.059 0.059
Plasmodium falciparum metacaspase-like protein 0.0026 0.0026 0.0117
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0095 0.0239 0.0263
Schistosoma mansoni hypothetical protein 0.0838 0.2523 0.2523
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0021 0.0028
Echinococcus multilocularis microtubule associated protein 2 0.2778 0.8493 0.8493
Mycobacterium ulcerans two component sensor kinase MprB 0.0042 0.0076 0.0092
Brugia malayi hypothetical protein 0.0032 0.0044 0.0177
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.006 0.0187
Trypanosoma cruzi ISWI complex protein 0.0024 0.002 0.0054
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0139 0.0139
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.019 0.0531 0.0531
Schistosoma mansoni alpha glucosidase 0.0037 0.006 0.0059
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0047 0.0089 0.0089
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.005
Loa Loa (eye worm) endoplasmin 0.0134 0.0357 0.0434
Brugia malayi jmjC domain containing protein 0.004 0.007 0.028
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0579 0.1728 0.4656
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0458 0.1233
Echinococcus multilocularis neuropeptide receptor A26 0.0943 0.2847 0.2847
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0028 0.0034 0.0033
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.0002 0.0012
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0089 0.0108
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.005
Echinococcus multilocularis disco interacting protein 2 0.004 0.0068 0.0068
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0245 0.0699 0.8376
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.006 0.0132 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-31 0.006 0.0132 0.0531
Loa Loa (eye worm) hypothetical protein 0.0026 0.0026 0.0031
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0109 0.0281 0.0281
Loa Loa (eye worm) RecQ helicase 0.0044 0.0082 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0146 0.0391
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.022 0.022
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0028 0.0034 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0089 0.0108
Echinococcus granulosus nuclear receptor nhr 48 0.0028 0.0034 0.0034
Plasmodium vivax endoplasmin, putative 0.0134 0.0357 0.1627
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0042 0.0076 0.0254
Loa Loa (eye worm) hypothetical protein 0.0109 0.0281 0.0341
Schistosoma mansoni hypothetical protein 0.3268 1 1
Echinococcus multilocularis phosphoglycerate kinase 1 0.0166 0.0458 0.0458
Loa Loa (eye worm) heat shock protein 75 0.0057 0.0122 0.0148
Brugia malayi Pre-SET motif family protein 0.0065 0.0145 0.0586
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0221 0.0221
Echinococcus granulosus phd:f box containing protein 0.004 0.007 0.007
Echinococcus granulosus histone acetyltransferase MYST2 0.0109 0.0281 0.0281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0106 0.0375
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Leishmania major mitochondrial DNA polymerase beta 0.1224 0.3711 1
Brugia malayi beta-NAC-like protein 0.0069 0.0158 0.0639
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Trypanosoma brucei unspecified product 0.0039 0.0067 0.0179
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0014 0.0077
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0121 0.0487
Trypanosoma cruzi DNA polymerase kappa, putative 0.0057 0.0121 0.0325
Trypanosoma cruzi DNA topoisomerase III, putative 0.0051 0.0103 0.0275
Echinococcus granulosus importin subunit beta 1 0.003 0.0038 0.0038
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0021 0.0028
Trypanosoma brucei heat shock protein, putative 0.0134 0.0357 0.0962
Echinococcus multilocularis expressed protein 0.0025 0.0023 0.0023
Onchocerca volvulus 0.0096 0.0242 0.1624
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0075
Brugia malayi DNA topoisomerase III 0.0051 0.0103 0.0413
Brugia malayi nuclear receptor NHR-88 0.0028 0.0034 0.0135
Echinococcus granulosus expressed protein 0.0025 0.0023 0.0023
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0041 0.0166
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.003
Schistosoma mansoni apoferritin-2 0.0025 0.0023 0.0022
Plasmodium falciparum basic transcription factor 3b, putative 0.0069 0.0158 0.072
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0166 0.0458 0.3527
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0129 0.0344 0.0344
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0047 0.0089 0.024
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0041 0.0041
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0117 0.0142
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0053 0.0239
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0026 0.0069
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0042 0.0076 0.0065
Entamoeba histolytica Ran family GTPase 0.0022 0.0014 0.001
Loa Loa (eye worm) hypothetical protein 0.0055 0.0115 0.0139
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Entamoeba histolytica hypothetical protein 0.0176 0.0489 0.0587
Mycobacterium ulcerans DNA polymerase IV 0.0057 0.0121 0.0146
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0198 0.0198
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0166 0.0458 0.3527
Trichomonas vaginalis sphingosine kinase, putative 0.0105 0.0269 0.1038
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0269 0.032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.006 0.0132 0.0531
Schistosoma mansoni zinc finger protein 0.0028 0.0034 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.005
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0068 0.0154 0.1187
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0042 0.0076 0.0162
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0134 0.036
Echinococcus multilocularis Diacylglycerol kinase theta 0.0105 0.0269 0.0269
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0042 0.0076 0.0065
Entamoeba histolytica diacylglycerol kinase, putative 0.0105 0.0269 0.032
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0041 0.0041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.006 0.0132 0.0132
Trypanosoma brucei metacaspase MCA2 0.0026 0.0026 0.0069
Toxoplasma gondii hypothetical protein 0.0031 0.0041 0.0317
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0042 0.0076 0.0065
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.006 0.0132 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0026 0.0049
Brugia malayi MH1 domain containing protein 0.0018 0.0001 0.0004
Trypanosoma brucei DNA topoisomerase IA, putative 0.0051 0.0103 0.0275
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0026 0.0069
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.0269 0.0725
Onchocerca volvulus 0.0031 0.0041 0.0193
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0166 0.0458 0.2003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0064
Loa Loa (eye worm) hypothetical protein 0.0152 0.0413 0.0501
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0095 0.0239 0.2677
Loa Loa (eye worm) hypothetical protein 0.0474 0.1404 0.1704
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0089 0.0101
Loa Loa (eye worm) hypothetical protein 0.0135 0.0361 0.0438
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0042 0.0076 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0269 0.1038
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0041
Echinococcus granulosus lamin 0.0053 0.011 0.011
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0002 0.0003
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0026 0.0049
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.004 0.007 0.0534
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0106 0.0375
Leishmania major heat shock protein 83-1 0.0134 0.0357 0.0962
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0038 0.0173
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0047 0.003
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0018 0.008
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0019 0.0006 0.004
Loa Loa (eye worm) hypothetical protein 0.0082 0.0198 0.024
Loa Loa (eye worm) hypothetical protein 0.006 0.0132 0.016
Brugia malayi Diacylglycerol kinase protein 2 0.0105 0.0269 0.1087
Loa Loa (eye worm) DR-78 0.0028 0.0034 0.0041
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0344 0.0926
Loa Loa (eye worm) hypothetical protein 0.0135 0.0362 0.044
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0014 0.0014
Echinococcus granulosus heat shock protein 90 0.0134 0.0357 0.0357

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CXCR1 (IL-8A) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CCR2B radioligand binding (ligand: [125I] MCP-1) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Vascular Endothelial Growth Factor (VEGF) radioligand binding (ligand: [125I] VEGF) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Angiotensin AT2 radioligand binding (ligand: [125I] CGP-42112A) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Nitric Oxide Synthase, Neuronal (nNOS) radioligand binding (ligand: [3H]L-Arginine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CXCR2 (IL-8B) radioligand binding (ligand: [125I] IL-8) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Vasoactive Intestinal Peptide VIP1 radioligand binding (ligand: [125I] VIP) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Peptidase, Matrix Metalloprotease-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cholecystokinin CCKA radioligand binding (ligand: [3H] L-364,718) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protease, Cathepsin G enzyme inhibition (substrate: Suc-Ala-Ala-Pro-Phe-AMC) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Alpha-1B adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CCR5 radioligand binding (ligand: [125I] MIP-1alpha) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Aldose Reductase enzyme inhibition (substrate: DL-Glyceraldehyde) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Glycine, Strychnine-Sensitive radioligand binding (ligand: [3H] Strychnine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Peptidase, Angiotensin Converting Enzyme enzyme inhibition (substrate: FAPGG) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Neuropeptide Y Y2 radioligand binding (ligand: [125I] Peptide YY) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: HMG-CoA Reductase enzyme inhibition (substrate: [14C]HMG-CoA) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Nitric Oxide Synthase, Inducible (iNOS) enzyme inhibition (substrate: L-Arginine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Insulin radioligand binding (ligand: [125I] Insulin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Kinase PKCalpha enzyme inhibition (substrate: Histone) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Estrogen ERbeta radioligand binding (ligand: [3H] Estradiol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Bradykinin B2 radioligand binding (ligand: [3H] Bradykinin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Alpha-1A adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Leukotriene LTC4 Synthase enzyme inhibition (substrate: LTA4) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 2A6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Calcitonin radioligand binding (ligand: [125I] Calcitonin (salmon)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Tachykinin NK2 radioligand binding (ligand: [3H] SR-48968) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Phosphodiesterase PDE5 enzyme inhibition (substrate: [3H]cGMP + cGMP) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Neuropeptide Y Y1 radioligand binding (ligand: [125I] Peptide YY) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2) ChEMBL. No reference
IC50 (binding) DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390) ChEMBL. No reference
IC50 (binding) = 0.3 uM DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
IC50 (binding) = 1.4118 uM DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine) ChEMBL. No reference
IC50 (binding) = 3.6443 uM DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) ChEMBL. No reference
IC50 (binding) = 3.9099 uM DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55) ChEMBL. No reference
IC50 (binding) = 3.9533 uM DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol) ChEMBL. No reference
IC50 (binding) = 6.9071 uM DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) ChEMBL. No reference
IC50 (binding) = 76 uM Inhibition of C-terminal His6-tagged Francisella tularensis SCHU S4 FabI expressed in Escherichia coli BL21 (DE3) using CrCoA as substrate assessed as oxidation of NADH to NAD+ by fluorescence assay ChEMBL. 23815100
Ki (binding) DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1B radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Angiotensin AT2 radioligand binding (ligand: [125I] CGP-42112A) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adrenergic beta3 radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Endothelin ETA radioligand binding (ligand: [125I] Endothelin-1) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Alpha-1A adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Phosphatase, PPP3CA (Calcineurin, PP2B) enzyme inhibition (substrate: DiFMUP) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cannabinoid CB1 radioligand binding (ligand: [3H] SR141716A) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Carbonic Anhydrase II enzyme inhibition (substrate: 4-Nitrophenyl acetate (4-NPA)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: HMG-CoA Reductase enzyme inhibition (substrate: [14C]HMG-CoA) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Estrogen ERalpha radioligand binding (ligand: [3H] Estradiol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Phosphodiesterase PDE5 enzyme inhibition (substrate: [3H]cGMP + cGMP) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CCR5 radioligand binding (ligand: [125I] MIP-1alpha) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CXCR2 (IL-8B) radioligand binding (ligand: [125I] IL-8) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2E1 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Melanocortin MC3 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Neuropeptide Y Y2 radioligand binding (ligand: [125I] Peptide YY) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M3 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 2A6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Dopamine Transporter radioligand binding (ligand: [125I] RTI-55) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Kinase PKCalpha enzyme inhibition (substrate: Histone) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Histamine H2 radioligand binding (ligand: [125I] Aminopotentidine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cyclooxygenase COX-2 enzyme inhibition (substrate: Arachidonic acid) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M2 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adrenergic beta2 radioligand binding (ligand: [3H] CGP-12177) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Glycine, Strychnine-Sensitive radioligand binding (ligand: [3H] Strychnine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protease, Caspase 1 enzyme inhibition (substrate: Ac-YVAD-AMC) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CCR4 radioligand binding (ligand: [125I] TARC) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Dopamine D1 radioligand binding (ligand: [3H] SCH-23390) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cholecystokinin CCKA radioligand binding (ligand: [3H] L-364,718) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M5 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Peptidase, ELA2 (Neutrophil Elastase 2) enzyme inhibition (substrate: N-MeOSuc-Ala-Ala-Pro-Val-pNA) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Tyrosine Kinase, ERBB2 (HER2) enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Nitric Oxide Synthase, Neuronal (nNOS) radioligand binding (ligand: [3H]L-Arginine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Peptidase, Matrix Metalloprotease-1 (MMP-1) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Estrogen ERbeta radioligand binding (ligand: [3H] Estradiol) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Leukotriene LTC4 Synthase enzyme inhibition (substrate: LTA4) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CCR2B radioligand binding (ligand: [125I] MCP-1) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Muscarinic M1 radioligand binding (ligand: [3H] N-Methylscopolamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Neuropeptide Y Y1 radioligand binding (ligand: [125I] Peptide YY) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Bradykinin B2 radioligand binding (ligand: [3H] Bradykinin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protease, Cathepsin G enzyme inhibition (substrate: Suc-Ala-Ala-Pro-Phe-AMC) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Chemokine CXCR1 (IL-8A) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Tachykinin NK2 radioligand binding (ligand: [3H] SR-48968) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Vasoactive Intestinal Peptide VIP1 radioligand binding (ligand: [125I] VIP) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Insulin radioligand binding (ligand: [125I] Insulin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Histamine H1, Central radioligand binding (ligand: [3H] Pyrilamine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Aldose Reductase enzyme inhibition (substrate: DL-Glyceraldehyde) ChEMBL. No reference
Ki (binding) DRUGMATRIX: CYP450, 1A2 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Thromboxane Synthetase enzyme inhibition (substrate: PGH2) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Vascular Endothelial Growth Factor (VEGF) radioligand binding (ligand: [125I] VEGF) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Tachykinin NK1 radioligand binding (ligand: [3H] Substance P) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Vasopressin V1A radioligand binding (ligand: [125I] PhenylacetylTyr(Me)PheGlnAsnArgProArgTyr) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT6 radioligand binding (ligand: [3H] Lysergic acid diethylamide) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Calcitonin radioligand binding (ligand: [125I] Calcitonin (salmon)) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Peptidase, Angiotensin Converting Enzyme enzyme inhibition (substrate: FAPGG) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Alpha-1B adrenergic receptor radioligand binding (ligand: prazosin) ChEMBL. No reference
Ki (binding) DRUGMATRIX: Nitric Oxide Synthase, Inducible (iNOS) enzyme inhibition (substrate: L-Arginine) ChEMBL. No reference
Ki (binding) = 0.75 uM DRUGMATRIX: Transporter, Serotonin (5-Hydroxytryptamine) (SERT) radioligand binding (ligand: [3H] Paroxetine) ChEMBL. No reference
Ki (binding) = 1.3666 uM DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) ChEMBL. No reference
Ki (binding) = 1.6615 uM DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol) ChEMBL. No reference
Ki (binding) = 3.8775 uM DRUGMATRIX: Norepinephrine Transporter radioligand binding (ligand: [125I] RTI-55) ChEMBL. No reference
MIC (functional) = 0.006 mg l-1 In vitro antifungal activity against Trichophyton mentagrophytes expressed as MIC (mg/L) ChEMBL. 8340915
MIC (functional) = 0.01 mg l-1 In vitro antifungal activity against Microsporum canis expressed as MIC (mg/L) ChEMBL. 8340915
MIC (functional) = 0.2 mg l-1 In vitro antifungal activity against Sporothrix schenck ii expressed as MIC (mg/L) ChEMBL. 8340915
MIC (functional) = 0.4 mg l-1 In vitro antifungal activity against Aspergillus fumigatus expressed as MIC (mg/L) ChEMBL. 8340915
MIC (functional) = 0.8 mg l-1 In vitro antifungal activity against Candida parapsilosis delta39 expressed as MIC (mg/L) ChEMBL. 8340915
MIC (functional) = 12.5 mg l-1 In vitro antifungal activity against Candida albicans delta9 expressed as MIC (mg/L) ChEMBL. 8340915
MIC (functional) = 12.5 mg l-1 In vitro antifungal activity against Candida albicans delta9 expressed as MIC (mg/L) ChEMBL. 8340915
MIC (functional) = 25 mg l-1 In vitro antifungal activity against Candida albicans delta124 expressed as MIC (mg/L) ChEMBL. 8340915
MIC (functional) = 25 mg l-1 In vitro antifungal activity against Candida albicans delta124 expressed as MIC (mg/L) ChEMBL. 8340915
MIC (functional) = 0.04 ug ml-1 Antifungal activity against Trichophyton tonsurans after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.05 ug ml-1 Antifungal activity against Trichophyton rubrum after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.059 ug ml-1 Antifungal activity against Trichophyton soudanense after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.063 ug ml-1 Antifungal activity against Trichophyton mentagrophytes after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.063 ug ml-1 Antifungal activity against Trichophyton violaceum after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.074 ug ml-1 Antifungal activity against Trichophyton sp. after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.081 ug ml-1 Antifungal activity against Epidermophyton floccosum after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.084 ug ml-1 Antifungal activity against Microsporum gypseum after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.101 ug ml-1 Antifungal activity against Microsporum canis after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.106 ug ml-1 Antifungal activity against Microsporum sp. after 7 days by broth microdilution test ChEMBL. 17371821
MIC (functional) = 0.153 ug ml-1 Antifungal activity against Microsporum cookei after 7 days by broth microdilution test ChEMBL. 17371821
MIC50 (functional) = 0.031 ug ml-1 Antifungal activity against Trichophyton tonsurans after 7 days by broth microdilution test ChEMBL. 17371821
MIC50 (functional) = 0.063 ug ml-1 Antifungal activity against Trichophyton rubrum after 7 days by broth microdilution test ChEMBL. 17371821
MIC50 (functional) = 0.063 ug ml-1 Antifungal activity against Trichophyton mentagrophytes after 7 days by broth microdilution test ChEMBL. 17371821
MIC50 (functional) = 0.063 ug ml-1 Antifungal activity against Trichophyton sp. after 7 days by broth microdilution test ChEMBL. 17371821
MIC50 (functional) = 0.125 ug ml-1 Antifungal activity against Microsporum sp. after 7 days by broth microdilution test ChEMBL. 17371821
MIC80 (functional) = 1 ug ml-1 Antifungal activity against Cryptococcus neoformans after 72 hrs by broth microdilution method ChEMBL. 24051242
MIC90 (functional) = 0.063 ug ml-1 Antifungal activity against Trichophyton tonsurans after 7 days by broth microdilution test ChEMBL. 17371821
MIC90 (functional) = 0.125 ug ml-1 Antifungal activity against Trichophyton rubrum after 7 days by broth microdilution test ChEMBL. 17371821
MIC90 (functional) = 0.125 ug ml-1 Antifungal activity against Trichophyton mentagrophytes after 7 days by broth microdilution test ChEMBL. 17371821
MIC90 (functional) = 0.125 ug ml-1 Antifungal activity against Trichophyton sp. after 7 days by broth microdilution test ChEMBL. 17371821
MIC90 (functional) = 0.125 ug ml-1 Antifungal activity against Microsporum sp. after 7 days by broth microdilution test ChEMBL. 17371821
Potency (functional) 0.0112 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.9811 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 13.4591 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.9959 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.0115 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 21.3138 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 31.6228 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) 33.4889 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 33.4983 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: Inhibitors of USP1/UAF1: Pilot qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504878] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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