Detailed information for compound 1110188

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1149.55 | Formula: C59H108N10O12
  • H donors: 10 H acceptors: 12 LogP: 5.59 Rotable bonds: 46
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCCCC[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NC(C(=O)NC(C(=O)N[C@H](C(=O)N[C@H](C(=O)NC(C(=O)NC(C(=O)N[C@H](CN(CCO)C)C)(C)C)(C)C)C(C)C)C(C)C)(C)C)(C)C)C[C@@H](C[C@@H](CC(=O)CC)O)C)C
  • InChi: 1S/C59H108N10O12/c1-19-21-22-23-24-25-27-39(8)51(77)69-29-26-28-44(69)48(74)61-43(33-38(7)32-42(72)34-41(71)20-2)47(73)64-58(14,15)54(80)67-57(12,13)53(79)63-45(36(3)4)49(75)62-46(37(5)6)50(76)65-59(16,17)55(81)66-56(10,11)52(78)60-40(9)35-68(18)30-31-70/h36-40,42-46,70,72H,19-35H2,1-18H3,(H,60,78)(H,61,74)(H,62,75)(H,63,79)(H,64,73)(H,65,76)(H,66,81)(H,67,80)/t38-,39-,40+,42+,43+,44+,45+,46+/m1/s1
  • InChiKey: KBWBVJMZIOXEBP-ULIOYMGRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Kinase, CMGC MAPK 0.1546 0.1617 1
Leishmania major GTP-binding protein, putative 0.0024 0.0005 0.0013
Echinococcus granulosus acetylcholinesterase 0.1485 0.1553 0.1553
Brugia malayi Casein kinase II, alpha chain 0.0169 0.0159 0.0751
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0015
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0104 0.049
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.027 0.0266 0.2334
Trypanosoma cruzi cysteine peptidase, putative 0.059 0.0605 0.1743
Brugia malayi cathepsin L-like precursor 0.0751 0.0775 0.3661
Loa Loa (eye worm) hypothetical protein 0.0054 0.0037 0.0177
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Loa Loa (eye worm) doublecortin family protein 0.0019 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0037 0.0325
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0112 0.0531
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0017 0.0017
Leishmania major acetyl-CoA carboxylase, putative 0.0835 0.0864 0.2366
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0036 0.0019 0.0019
Schistosoma mansoni cathepsin F (C01 family) 0.1094 0.1139 0.538
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0054 0.0037 0.0176
Brugia malayi cathepsin L precursor 0.0247 0.0241 0.114
Brugia malayi PAS domain containing protein 0.0055 0.0038 0.0181
Giardia lamblia Cathepsin L precursor 0.0247 0.0241 0.1464
Schistosoma mansoni kinase 0.0126 0.0113 0.0535
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0017 0.0222
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0017 0.0106
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1466 0.1533 0.1533
Trichomonas vaginalis phosphofructokinase, putative 0.0123 0.011 0.0682
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0378 0.038 0.1795
Loa Loa (eye worm) hypothetical protein 0.0247 0.0241 0.114
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0069 0.0053 0.0053
Toxoplasma gondii biotin-requiring enzyme domain-containing protein 0.0029 0.0011 0.0047
Giardia lamblia Cysteine protease 0.0247 0.0241 0.1464
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0225 0.1388
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0225 0.1388
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0247 0.0241 0.2115
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.006 0.0282
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0012 0.0057
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0479 0.0488 0.4282
Leishmania major casein kinase II, putative 0.0169 0.0159 0.0434
Echinococcus multilocularis casein kinase ii subunit beta 0.0041 0.0024 0.0024
Giardia lamblia Cathepsin L-like protease 0.0247 0.0241 0.1464
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0247 0.0241 0.2115
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0818 0.0846 0.0846
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0036 0.0019 0.0087
Trypanosoma cruzi polo-like protein kinase, putative 0.0231 0.0225 0.0646
Brugia malayi PXA domain containing protein 0.0023 0.0005 0.0023
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0113 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0114 0.01 0.0474
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0007 0.0033
Giardia lamblia Encystation-specific protease 0.0247 0.0241 0.1464
Schistosoma mansoni hypothetical protein 0.017 0.016 0.0757
Echinococcus multilocularis snurportin 1 0.0345 0.0345 0.0345
Leishmania major cathepsin L-like protease 0.1144 0.1192 0.3265
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0288 0.0285 0.0821
Echinococcus multilocularis cysteine protease 0.1094 0.1139 0.1139
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0149 0.0138 0.0652
Brugia malayi Calcitonin receptor-like protein seb-1 0.011 0.0097 0.0457
Brugia malayi Cytochrome P450 family protein 0.0025 0.0007 0.0033
Entamoeba histolytica hypothetical protein 0.0026 0.0008 0.0069
Echinococcus multilocularis voltage dependent calcium channel 0.0036 0.0019 0.0019
Brugia malayi hypothetical protein 0.0185 0.0176 0.083
Chlamydia trachomatis biotin carboxylase 0.0289 0.0286 1
Leishmania major mitochondrial DNA polymerase beta 0.0297 0.0294 0.0805
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.017 0.016 0.016
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0808 0.0835 0.2288
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0146 0.2256
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0041 0.0024 0.0207
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0017 0.0048
Trypanosoma brucei acetyl-CoA carboxylase 0.0835 0.0864 0.5341
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0001 0.0001
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0029 0.0011 0.0121
Onchocerca volvulus 0.1094 0.1139 1
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0003 0.0003
Leishmania major phosphatidylinositol kinase, putative 0.017 0.016 0.0438
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2018 0.2117 1
Plasmodium vivax vivapain-2 0.1094 0.1139 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0428 0.0433 0.2047
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.0241 0.114
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0001 0.0003
Echinococcus granulosus GPCR family 2 0.0035 0.0017 0.0017
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.017 0.016 0.1403
Echinococcus granulosus lamin 0.003 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0076 0.006 0.0285
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.027 0.0266 0.1258
Loa Loa (eye worm) hypothetical protein 0.0247 0.0241 0.114
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Brugia malayi hypoxia-induced factor 1 0.017 0.0161 0.0759
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0008 0.0047
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.0072 0.0056 0.016
Brugia malayi Serotonin receptor 0.0528 0.0539 0.2547
Mycobacterium ulcerans branched-chain alpha-keto acid dehydrogenase subunit E2 0.0029 0.0011 0.0121
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0113 0.01 0.3233
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0458 0.0466 0.2199
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0098 0.0084 0.0084
Schistosoma mansoni neuroligin 3 (S09 family) 0.0251 0.0246 0.1161
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0987 0.1025 0.4842
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0187 0.0178 0.0511
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.006 0.006
Loa Loa (eye worm) hypoxia-induced factor 1 0.017 0.0161 0.0759
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0129 0.0351
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0149 0.0138 0.0138
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0003 0.0015
Giardia lamblia Cathepsin L precursor 0.0247 0.0241 0.1464
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.0241 0.1491
Brugia malayi Carboxyl transferase domain containing protein 0.0805 0.0833 0.3935
Trichomonas vaginalis PIKK family atypical protein kinase 0.0808 0.0835 0.5165
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0818 0.0846 0.0846
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0017 0.008
Trypanosoma cruzi dihydrolipoamide acetyltransferase, putative 0.0029 0.0011 0.003
Onchocerca volvulus 0.0035 0.0017 0.0149
Leishmania major hypothetical protein, conserved 0.3465 0.3648 1
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0003 0.0015
Giardia lamblia Cysteine protease 0.0247 0.0241 0.1464
Plasmodium falciparum serine repeat antigen 1 0.0247 0.0241 0.2115
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0987 0.1025 0.2954
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0828 0.0857 0.7527
Onchocerca volvulus 0.0247 0.0241 0.2115
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.027 0.0266 0.1643
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0761 0.0786 0.4858
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.059 0.0605 0.3742
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0587 0.0602 0.37
Brugia malayi hypothetical protein 0.0114 0.0101 0.0475
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0024 0.0146
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0751 0.0775 0.4792
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0017 0.0222
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0034 0.0096
Schistosoma mansoni lamin 0.003 0.0012 0.0057
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0005 0.0042
Toxoplasma gondii cathepsin CPL 0.1094 0.1139 0.7037
Giardia lamblia Hypothetical protein 0.0247 0.0241 0.1464
Echinococcus multilocularis cathepsin L cysteine protease 0.1094 0.1139 0.1139
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E2 0.0029 0.0011 0.0047
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0082
Schistosoma mansoni hypothetical protein 0.0345 0.0345 0.163
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0129 0.0793
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.1546 0.1617 0.4431
Trichomonas vaginalis PIKK family atypical protein kinase 0.0782 0.0808 0.4994
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0247 0.0241 0.1464
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.0241 0.1491
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0015 0.0074
Entamoeba histolytica protein kinase domain containing protein 0.0072 0.0056 0.0491
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.0835 0.0864 0.5333
Schistosoma mansoni protein kinase 0.0169 0.0159 0.0751
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1094 0.1139 0.7043
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0003 0.0015
Echinococcus granulosus casein kinase ii subunit alpha 0.0169 0.0159 0.0159
Plasmodium falciparum serine repeat antigen 7 0.0247 0.0241 0.2115
Brugia malayi Importin beta-1 subunit 0.0032 0.0014 0.0067
Echinococcus multilocularis 6 phosphofructokinase 0.0123 0.011 0.011
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0041 0.0024 0.0067
Giardia lamblia Cathepsin B precursor 0.0247 0.0241 0.1464
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0027 0.0008 0.0008
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0113 0.01 0.153
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.003 0.0012 0.0076
Echinococcus multilocularis cathepsin L 0.0247 0.0241 0.0241
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.0294 0.0847
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0442 0.0448 0.0448
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0015 0.013
Brugia malayi Cathepsin L-like precursor 0.1094 0.1139 0.538
Trichomonas vaginalis PIKK family atypical protein kinase 0.0782 0.0808 0.4994
Echinococcus multilocularis protein kinase shaggy 0.0072 0.0056 0.0056
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0112 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0802 0.083 0.513
Giardia lamblia Kinase, CMGC GSK 0.0072 0.0056 0.0315
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0041 0.0024 0.0128
Schistosoma mansoni hypothetical protein 0.0109 0.0095 0.045
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0053 0.0328
Giardia lamblia Phosphatidylinositol 4-kinase 0.017 0.016 0.0962
Trypanosoma cruzi cysteine protease, putative 0.059 0.0605 0.1743
Brugia malayi Papain family cysteine protease containing protein 0.1094 0.1139 0.538
Trichomonas vaginalis PIKK family atypical protein kinase 0.0191 0.0182 0.1126
Brugia malayi Papain family cysteine protease containing protein 0.0247 0.0241 0.114
Schistosoma mansoni survival motor neuron protein 0.0109 0.0095 0.045
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0428 0.0433 0.2679
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0015 0.0074
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0094
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0005 0.0012
Mycobacterium leprae Probable lipase LipE 0.0035 0.0017 0.0446
Echinococcus granulosus cathepsin L 0.059 0.0605 0.0605
Leishmania major carboxylase, putative 0.0318 0.0317 0.0867
Entamoeba histolytica hypothetical protein 0.017 0.016 0.1407
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0005 0.0033
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0113 0.01 0.153
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1094 0.1139 0.538
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0247 0.0241 0.2115
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0017 0.008
Plasmodium falciparum dihydrolipoamide acyltransferase component E2 0.0029 0.0011 0.0093
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0428 0.0433 0.3804
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0008 0.0047
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0003 0.0003
Brugia malayi Papain family cysteine protease containing protein 0.059 0.0605 0.2859
Trypanosoma cruzi major cysteine proteinase, putative 0.0297 0.0294 0.0846
Echinococcus granulosus single minded 2 0.0041 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0247 0.0241 0.114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Loa Loa (eye worm) phosphatidylinositol 3 0.1309 0.1365 0.6451
Plasmodium vivax serine-repeat antigen (SERA) 0.0247 0.0241 0.2115
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0247 0.0241 0.1464
Plasmodium falciparum serine repeat antigen 6 0.0247 0.0241 0.2115
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0015
Giardia lamblia Cathepsin L precursor 0.0247 0.0241 0.1464
Mycobacterium ulcerans hypothetical protein 0.0156 0.0146 0.2256
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0017 0.0222
Plasmodium falciparum serine repeat antigen 9 0.0247 0.0241 0.2115
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.059 0.0605 0.2859
Echinococcus multilocularis voltage dependent calcium channel 0.0036 0.0019 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0828 0.0857 0.247
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0098 0.0084 0.0084
Leishmania major protein kinase, putative 0.0032 0.0014 0.0037
Brugia malayi Papain family cysteine protease containing protein 0.0247 0.0241 0.114
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0113 0.01 0.0598
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0029 0.0011 0.0052
Mycobacterium ulcerans hypothetical protein 0.0029 0.0011 0.0121
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0123 0.011 0.0679
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0018
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0113 0.01 0.0614
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0297 0.0294 0.1817
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0036 0.0019 0.0019
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0142 0.0131 0.1149
Leishmania major hypothetical protein, conserved 0.0035 0.0017 0.0046
Brugia malayi hypothetical protein 0.0019 0 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0149 0.0138 0.0652
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0113 0.01 0.153
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0247 0.0241 0.2115
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.059 0.0605 0.2859
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0016
Loa Loa (eye worm) beta-lactamase 0.0035 0.0017 0.0082
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0112 0.1729
Echinococcus granulosus BC026374 protein S09 family 0.0251 0.0246 0.0246
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.017 0.016 0.046
Plasmodium vivax hypothetical protein, conserved 0.017 0.016 0.1403
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0069 0.0053 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0022 0.0103
Plasmodium vivax unspecified product 0.059 0.0605 0.5312
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0247 0.0241 0.1491
Echinococcus granulosus casein kinase ii subunit beta 0.0041 0.0024 0.0024
Leishmania major dihydrolipoamide branched chain transacylase, putative 0.0029 0.0011 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0072 0.0056 0.0345
Loa Loa (eye worm) carboxylesterase 0.1485 0.1553 0.7336
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0003 0.0026
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Plasmodium vivax vivapain-1 0.059 0.0605 0.5312
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.1094 0.1139 0.538
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0828 0.0857 0.53
Echinococcus multilocularis dnaJ subfamily B 0.0434 0.044 0.044
Leishmania major cathepsin L-like protease 0.1094 0.1139 0.312
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0003 0.0003
Onchocerca volvulus 0.1094 0.1139 1
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0029 0.0011 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0225 0.1388
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0458 0.0466 0.2876
Brugia malayi Cathepsin L-like precursor 0.1094 0.1139 0.538
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0029 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Loa Loa (eye worm) hypothetical protein 0.0751 0.0775 0.3661
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0247 0.0241 0.1491
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1094 0.1139 0.7043
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0029 0.0011 0.003
Onchocerca volvulus 0.0114 0.01 0.0878
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.0241 0.1491
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0053 0.0328
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0817 0.0845 0.7417
Echinococcus granulosus cpg binding protein 0.0062 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0251 0.0246 0.1161
Schistosoma mansoni ran 0.0024 0.0005 0.0025
Loa Loa (eye worm) phosphatidylinositol 3 0.0828 0.0857 0.405
Trypanosoma cruzi acetyl-CoA carboxylase 0.0517 0.0527 0.1519
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0489 0.0498 0.3064
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0123 0.011 0.0682
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0721 0.0744 0.0744
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0225 0.1388
Entamoeba histolytica serine/threonine protein kinase, putative 0.0231 0.0225 0.1972
Echinococcus granulosus survival motor neuron protein 1 0.0533 0.0544 0.0544
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0015 0.013
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0247 0.0241 0.1464
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0318 0.0317 0.0912
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0378 0.038 0.3333
Echinococcus granulosus cathepsin l1 0.1094 0.1139 0.1139
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0003 0.0003
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.027 0.0266 0.1645
Onchocerca volvulus 0.017 0.016 0.1403
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0072 0.0056 0.0264
Brugia malayi FAT domain containing protein 0.0319 0.0318 0.1501
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0251 0.0246 0.1519
Schistosoma mansoni cathepsin S (C01 family) 0.0247 0.0241 0.114
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.017 0.016 0.046
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0828 0.0857 0.2348
Echinococcus multilocularis casein kinase ii subunit alpha 0.0169 0.0159 0.0159
Echinococcus multilocularis Biotin lipoyl attachment 0.0029 0.0011 0.0011
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0007 0.0033
Giardia lamblia Kinase, CMGC CK2 0.0169 0.0159 0.0954
Mycobacterium tuberculosis Biotinylated protein TB7.3 0.0029 0.0011 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.1546 0.1617 0.7639
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0987 0.1025 0.6338
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0015 0.0062
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0818 0.0846 0.3996
Brugia malayi Doublecortin family protein 0.0019 0 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0159 0.0982
Trypanosoma cruzi major cysteine proteinase, putative 0.0247 0.0241 0.0694
Entamoeba histolytica phosphofructokinase, putative 0.0123 0.011 0.0969
Leishmania major cathepsin L-like protease 0.1144 0.1192 0.3265
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.0241 0.1491
Loa Loa (eye worm) phosphatidylinositol kinase 0.017 0.016 0.0757
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.017 0.016 0.1407
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0112 0.0531
Brugia malayi beta-lactamase family protein 0.0035 0.0017 0.0082
Brugia malayi hypothetical protein 0.0054 0.0037 0.0177
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.006 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0489 0.0498 0.3078
Loa Loa (eye worm) hypothetical protein 0.0251 0.0246 0.1161
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0003 0.0015
Brugia malayi Protein kinase domain containing protein 0.0165 0.0155 0.0733
Echinococcus granulosus cathepsin b 0.2018 0.2117 0.2117
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0029 0.0011 0.0029
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0015 0.0154
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1094 0.1139 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0024 0.0068
Schistosoma mansoni lamin 0.003 0.0012 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Brugia malayi cathepsin Z-like cysteine proteinase 0.0247 0.0241 0.114
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0818 0.0846 0.3996
Trypanosoma cruzi cysteine peptidase, putative 0.1144 0.1192 0.3435
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0512 0.0522 0.4587
Brugia malayi M-phase phosphoprotein, mpp8 0.0114 0.01 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0802 0.083 0.513
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.1546 0.1617 0.7639
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0029 0.0011 0.003
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0113 0.01 0.153
Onchocerca volvulus 0.0035 0.0017 0.0149
Schistosoma mansoni importin beta-1 0.0032 0.0014 0.0067
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.003 0.0085
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.027 0.0266 0.2337
Schistosoma mansoni single-minded 0.0055 0.0038 0.0181
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0005 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0751 0.0775 0.6805
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1826 0.1913 0.1913
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0008 0.0047
Schistosoma mansoni aspartate carbamoyltransferase 0.0072 0.0056 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0001 0.0006
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0072 0.0056 0.0264
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.003 0.0012 0.0059
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.017 0.016 0.099
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0017 0.0048
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0053 0.0328
Brugia malayi Carboxylesterase family protein 0.0251 0.0246 0.1161
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0029 0.0011 0.0011
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0818 0.0846 0.2437
Echinococcus granulosus cathepsin L cysteine proteinase 0.1094 0.1139 0.1139
Echinococcus granulosus 6 phosphofructokinase 0.0123 0.011 0.011
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0344 0.0344 0.1625
Brugia malayi Carboxylesterase family protein 0.1485 0.1553 0.7336
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0029 0.0011 0.0011
Plasmodium vivax importin-beta 2, putative 0.0032 0.0014 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0761 0.0786 0.4858
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0247 0.0241 0.2118
Schistosoma mansoni hypothetical protein 0.0019 0 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0773 0.0798 0.4938
Echinococcus multilocularis cathepsin L cysteine protease 0.1094 0.1139 0.1139
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0017 0.0082
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0041 0.0024 0.0211
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0112 0.1729
Trichomonas vaginalis PIKK family atypical protein kinase 0.0761 0.0786 0.4858
Trypanosoma cruzi cysteine peptidase, putative 0.1144 0.1192 0.3435
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.017 0.016 0.0988
Onchocerca volvulus 0.0251 0.0246 0.2155
Schistosoma mansoni cpg binding protein 0.0062 0.0046 0.0216
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0072 0.0056 0.0056
Entamoeba histolytica hypothetical protein 0.0829 0.0858 0.7532
Echinococcus granulosus expressed conserved protein 0.0092 0.0078 0.0078
Echinococcus granulosus microtubule associated protein 2 0.0746 0.077 0.077
Trichomonas vaginalis spcc417.12 protein, putative 0.0251 0.0246 0.1519
Schistosoma mansoni cathepsin s 0.0344 0.0344 0.1625
Schistosoma mansoni ran 0.0024 0.0005 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0123 0.011 0.0682
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0003 0.0015
Entamoeba histolytica hypothetical protein 0.0076 0.006 0.053
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Echinococcus multilocularis lamin 0.003 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0067
Entamoeba histolytica hypothetical protein 0.0076 0.006 0.053
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0007 0.0018
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0113 0.01 0.0272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0247 0.0241 0.1491
Plasmodium falciparum serine repeat antigen 2 0.0247 0.0241 0.2115
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1094 0.1139 0.7043
Trypanosoma cruzi cruzipain precursor, putative 0.1144 0.1192 0.3435
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0082
Schistosoma mansoni acetylcholinesterase 0.0251 0.0246 0.1161
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Brugia malayi MH2 domain containing protein 0.0117 0.0104 0.049
Mycobacterium tuberculosis Probable branched-chain keto acid dehydrogenase E2 component BkdC 0.0029 0.0011 0.0121
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.017 0.016 0.0757
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0482 0.049 0.2317
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0113 0.0535
Brugia malayi cathepsin F-like cysteine proteinase 0.0247 0.0241 0.114
Plasmodium falciparum casein kinase II beta chain 0.0041 0.0024 0.0207
Onchocerca volvulus 0.1094 0.1139 1
Trypanosoma brucei protein kinase, putative 0.1546 0.1617 1
Loa Loa (eye worm) hypothetical protein 0.0251 0.0246 0.1161
Onchocerca volvulus 0.1094 0.1139 1
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0318 0.0317 0.0317
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.1546 0.1617 0.4661
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0801 0.0828 0.2386
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0072 0.0056 0.0489
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0048 0.003 0.0144
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0 0.0001
Echinococcus granulosus carboxylesterase 5A 0.1485 0.1553 0.1553
Plasmodium falciparum cysteine proteinase falcipain 3 0.1094 0.1139 1
Mycobacterium ulcerans beta-lactamase 0.0035 0.0017 0.0222
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.027 0.0266 0.0266
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0003 0.0015
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0112 0.0112
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0251 0.0246 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.0225 0.1061
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.048 0.0488 0.2305
Trichomonas vaginalis PIKK family atypical protein kinase 0.0787 0.0813 0.5029
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0087
Schistosoma mansoni 6-phosphofructokinase 0.0123 0.011 0.0522
Trichomonas vaginalis PIKK family atypical protein kinase 0.0782 0.0808 0.4994
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0318 0.0317 0.1956
Trichomonas vaginalis ran, putative 0.0024 0.0005 0.0031
Entamoeba histolytica cysteine proteinase 1, putative 0.059 0.0605 0.5314
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0032 0.0014 0.0039
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0017 0.0017
Plasmodium vivax unspecified product 0.0247 0.0241 0.2115
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0828 0.0857 0.2348
Brugia malayi Carboxylesterase family protein 0.0251 0.0246 0.1161
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0012 0.0057
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0318 0.0317 0.0912
Echinococcus multilocularis survival motor neuron protein 1 0.0533 0.0544 0.0544
Plasmodium vivax hypothetical protein 0.017 0.016 0.1403
Brugia malayi hypothetical protein 0.0022 0.0003 0.0015
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0604 0.062 0.5439
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0039 0.0022 0.0103
Echinococcus multilocularis acetylcholinesterase 0.1485 0.1553 0.1553
Mycobacterium ulcerans carboxylesterase, LipT 0.0251 0.0246 0.3846
Loa Loa (eye worm) hypothetical protein 0.0317 0.0316 0.1491
Loa Loa (eye worm) phosphatidylinositol 3 0.017 0.016 0.0757
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0454 0.0461 0.4046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0003 0.0003
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.0072 0.0056 0.016
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0072 0.0056 0.0056
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1466 0.1533 0.724
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0047 0.003 0.0184
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.017 0.016 0.099
Echinococcus multilocularis cysteine protease 0.1094 0.1139 0.1139
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0101 0.0087 0.041
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0005 0.0033
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0017 0.0106
Giardia lamblia Cathepsin B precursor 0.0247 0.0241 0.1464
Toxoplasma gondii FATC domain-containing protein 0.0458 0.0466 0.2864
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0113 0.01 0.0272
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0024 0.0005 0.0029
Echinococcus multilocularis acetylcholinesterase 0.1485 0.1553 0.1553
Loa Loa (eye worm) hypothetical protein 0.0056 0.0039 0.0186
Mycobacterium tuberculosis Carboxylesterase LipT 0.0251 0.0246 0.3846
Toxoplasma gondii hypothetical protein 0.0061 0.0044 0.0253
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0318 0.0317 1
Loa Loa (eye worm) hypothetical protein 0.0489 0.0498 0.2352
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0069 0.0053 0.0328
Entamoeba histolytica hypothetical protein 0.0022 0.0003 0.0027
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0037 0.0106
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0019 0.0091
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0039 0.0022 0.0103
Echinococcus granulosus neuroligin 0.0251 0.0246 0.0246
Entamoeba histolytica cysteine protease, putative 0.1094 0.1139 1
Echinococcus granulosus dnaJ subfamily B 0.0434 0.044 0.044
Toxoplasma gondii cathepsin CPC2 0.0247 0.0241 0.1474
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0225 0.1388
Echinococcus multilocularis expressed conserved protein 0.0092 0.0078 0.0078
Echinococcus multilocularis cathepsin b 0.2018 0.2117 0.2117
Plasmodium falciparum serine repeat antigen 5 0.0247 0.0241 0.2115
Loa Loa (eye worm) 6-phosphofructokinase 0.0123 0.011 0.0522
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0251 0.0246 0.3846
Plasmodium vivax SET domain protein, putative 0.0035 0.0017 0.0145
Mycobacterium tuberculosis Probable oxidoreductase 0.0617 0.0634 1
Brugia malayi Papain family cysteine protease containing protein 0.0247 0.0241 0.114
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0053 0.0328
Plasmodium vivax unspecified product 0.0344 0.0344 0.3018
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0003 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.051 0.052 0.3213
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0003 0.0003
Entamoeba histolytica casein kinase, putative 0.0169 0.0159 0.1396
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0378 0.038 0.1795
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0428 0.0433 0.1248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0782 0.0808 0.4994
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0094
Giardia lamblia Cathepsin L precursor 0.0247 0.0241 0.1464
Trichomonas vaginalis PIKK family atypical protein kinase 0.017 0.016 0.099
Echinococcus multilocularis ribosomal protein S6 kinase delta 1 0.0019 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0225 0.1388
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0069 0.0053 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0044 0.0273
Entamoeba histolytica hypothetical protein 0.0247 0.0241 0.2118
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0017 0.0084
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0828 0.0857 0.0857
Trichomonas vaginalis PIKK family atypical protein kinase 0.0454 0.0461 0.2849
Loa Loa (eye worm) cathepsin B 0.0795 0.0821 0.388
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0041 0.0024 0.0145
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0098 0.0084 0.0397
Brugia malayi Protein kinase domain containing protein 0.0378 0.038 0.1795
Trichomonas vaginalis conserved hypothetical protein 0.0272 0.0268 0.1656
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0247 0.0241 0.114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.0241 0.1491
Loa Loa (eye worm) hypothetical protein 0.011 0.0097 0.0457
Brugia malayi Carboxylesterase family protein 0.1485 0.1553 0.7336
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.017 0.016 0.016
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0024 0.0068
Schistosoma mansoni cathepsin F (C01 family) 0.0751 0.0775 0.3661
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0029 0.0011 0.003
Echinococcus multilocularis geminin 0.037 0.0372 0.0372
Echinococcus multilocularis calcium activated potassium channel 0.002 0.0001 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.017 0.016 0.0757
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0212 0.0204 0.126
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1094 0.1139 0.7043
Brugia malayi intracellular kinase 0.0072 0.0056 0.0264
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0247 0.0241 0.114
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0069 0.0053 0.0328
Plasmodium falciparum GAF domain-related protein, putative 0.0022 0.0003 0.0026
Mycobacterium ulcerans short chain dehydrogenase 0.0617 0.0634 1
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0101 0.0087 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0247 0.0241 0.1491
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0022 0.0103
Brugia malayi 6-phosphofructokinase 0.0123 0.011 0.0522
Schistosoma mansoni acetyl-CoA carboxylase 0.0835 0.0864 0.4081
Entamoeba histolytica hypothetical protein 0.0458 0.0466 0.4088
Loa Loa (eye worm) hypothetical protein 0.0251 0.0246 0.1161
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0003 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0149 0.0138 0.0138
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.027 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0247 0.0241 0.114
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0247 0.0241 0.2118
Giardia lamblia Cathepsin B precursor 0.0795 0.0821 0.5063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.059 0.0605 0.374
Loa Loa (eye worm) hypothetical protein 0.0247 0.0241 0.114
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0015
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.003 0.0012 0.0012
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0202 0.0194 0.0918
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0318 0.0317 0.4971
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0024 0.0068
Schistosoma mansoni pyruvate carboxylase 0.0318 0.0317 0.1496
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0018
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0247 0.0241 0.114
Loa Loa (eye worm) hypothetical protein 0.0021 0.0002 0.001
Loa Loa (eye worm) phosphatidylinositol 3 0.017 0.016 0.0757
Giardia lamblia Kinase, CMGC GSK 0.0072 0.0056 0.0315
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2018 0.2117 1
Trichomonas vaginalis esterase, putative 0.0035 0.0017 0.0106
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.027 0.0266 0.1645
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1094 0.1139 0.538
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0003 0.0003
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0721 0.0744 0.0744
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0113 0.01 0.153
Brugia malayi fibroinase precursor 0.0247 0.0241 0.114
Onchocerca volvulus 0.1094 0.1139 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0018
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0109 0.0095 0.045
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Onchocerca volvulus Cathepsin L homolog 0.0247 0.0241 0.2115
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.017 0.016 0.1403
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0123 0.011 0.0317
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0017 0.0106
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0378 0.038 0.038
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Leishmania major phosphatidylinositol kinase related protein, putative 0.0187 0.0178 0.0486
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0029 0.0011 0.0052
Mycobacterium tuberculosis Conserved protein 0.0035 0.0017 0.0222
Mycobacterium ulcerans putative regulatory protein 0.0041 0.0023 0.0315
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0005 0.0013
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0247 0.0241 0.2115
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0015 0.013
Leishmania major phosphatidylinositol 3-kinase, putative 0.027 0.0266 0.0728
Plasmodium vivax casein kinase II beta chain, putative 0.0041 0.0024 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0018
Plasmodium vivax casein kinase II beta chain, putative 0.0041 0.0024 0.0207
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0828 0.0857 0.7527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1094 0.1139 0.7043
Loa Loa (eye worm) gastrulation defective protein 1 0.0148 0.0136 0.0644
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0029 0.0011 0.0052
Trichomonas vaginalis CMGC family protein kinase 0.1546 0.1617 1
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.027 0.0266 0.1258
Loa Loa (eye worm) hypothetical protein 0.0344 0.0344 0.1625
Plasmodium falciparum phosphatidylinositol 3-kinase 0.027 0.0266 0.2334
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0003 0.0015
Plasmodium vivax unspecified product 0.0169 0.0159 0.1393
Brugia malayi hypothetical protein 0.0533 0.0544 0.2572
Loa Loa (eye worm) hypothetical protein 0.1485 0.1553 0.7336
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0003 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.011 0.0681
Loa Loa (eye worm) hypothetical protein 0.1485 0.1553 0.7336
Brugia malayi Cathepsin L-like precursor 0.1094 0.1139 0.538
Schistosoma mansoni casein kinase II beta subunit 0.0041 0.0024 0.0113
Mycobacterium tuberculosis Conserved protein 0.0035 0.0017 0.0222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Giardia lamblia Cathepsin B precursor 0.0247 0.0241 0.1464
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0123 0.011 1
Giardia lamblia Cathepsin B precursor 0.0247 0.0241 0.1464
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0017 0.0104
Loa Loa (eye worm) hypothetical protein 0.0247 0.0241 0.114
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0104 0.049
Loa Loa (eye worm) hypothetical protein 0.0251 0.0246 0.1161
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.0835 0.0864 0.0864
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0017 0.008
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0202 0.0194 0.0918
Plasmodium vivax lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative 0.0029 0.0011 0.0093
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0113 0.01 0.3079
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0225 0.1388
Trypanosoma brucei dihydrolipoamide acetyltransferase E2 subunit, putative 0.0029 0.0011 0.0065
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0001 0.0006
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0101 0.0087 0.0087
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Schistosoma mansoni hypothetical protein 0.0075 0.006 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.0241 0.1491
Loa Loa (eye worm) hypothetical protein 0.0251 0.0246 0.1161
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0247 0.0241 0.1491
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0008 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0442 0.0448 0.277
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0247 0.0241 0.2115
Trichomonas vaginalis CMGC family protein kinase 0.1546 0.1617 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0247 0.0241 0.2115
Brugia malayi Protein kinase domain containing protein 0.0034 0.0016 0.0076
Brugia malayi Cytochrome P450 family protein 0.0025 0.0007 0.0033
Echinococcus granulosus cathepsin b 0.2018 0.2117 0.2117
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.017 0.016 0.1403
Schistosoma mansoni hypothetical protein 0.037 0.0372 0.1757
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0006 0.0006
Brugia malayi Cathepsin L-like cysteine proteinase 0.0751 0.0775 0.3661
Loa Loa (eye worm) hypothetical protein 0.0185 0.0176 0.083
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1094 0.1139 0.7043
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0029 0.0011 0.0052
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.027 0.0266 0.2337
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0029 0.0011 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Trichomonas vaginalis CMGC family protein kinase 0.0072 0.0056 0.0345
Leishmania major carbamoyl-phosphate synthase, putative 0.0072 0.0056 0.0152
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0773 0.0798 0.2187
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0149 0.0138 0.0652
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0442 0.0448 0.0448
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0036 0.0019 0.0019
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0017 0.0082
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0142 0.0131 0.0779
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.017 0.016 0.0988
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.017 0.016 0.0972
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0113 0.01 0.2905
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.0059
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0344 0.0344 0.1625
Schistosoma mansoni cathepsin F (C01 family) 0.1094 0.1139 0.538
Echinococcus multilocularis neuroligin 0.0251 0.0246 0.0246
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.0805 0.0833 0.3935
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0002
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.006 0.0285
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0258 0.0253 0.0728
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0029 0.0011 0.0052
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0003 0.0015
Schistosoma mansoni hypothetical protein 0.0058 0.0042 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0802 0.083 0.513
Loa Loa (eye worm) cysteine protease 0.1094 0.1139 0.538
Echinococcus multilocularis BC026374 protein (S09 family) 0.0251 0.0246 0.0246
Leishmania major protein kinase, putative 0.0032 0.0014 0.0037
Plasmodium falciparum dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 0.0029 0.0011 0.0093
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.017 0.016 0.0972
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.017 0.016 0.046
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0053 0.0328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1094 0.1139 0.7043
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0015 0.013
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0053 0.0328
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.0068 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0159 0.0982
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0328 0.0327 0.1998
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0029 0.0011 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Loa Loa (eye worm) hypothetical protein 0.0075 0.006 0.0282
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0029 0.0011 0.0244
Loa Loa (eye worm) acetylcholinesterase 1 0.1485 0.1553 0.7336
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0003 0.0015
Toxoplasma gondii cathepsin B 0.0795 0.0821 0.5069
Entamoeba histolytica protein kinase, putative 0.0023 0.0005 0.0043
Plasmodium vivax glycogen synthase kinase 3, putative 0.0072 0.0056 0.0488
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0745 0.0769 0.4753
Leishmania major cathepsin L-like protease 0.1094 0.1139 0.312
Echinococcus granulosus tyrosine protein kinase Lyn 0.0023 0.0005 0.0005
Trypanosoma brucei Casein kinase II 0.0169 0.0159 0.098
Plasmodium falciparum importin beta, putative 0.0032 0.0014 0.0121
Entamoeba histolytica phosphofructokinase, putative 0.0123 0.011 0.0969
Brugia malayi Papain family cysteine protease containing protein 0.059 0.0605 0.2859
Schistosoma mansoni voltage-gated cation channel 0.0036 0.0019 0.0087
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0005 0.0023
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0319 0.0318 0.0318
Echinococcus granulosus cathepsin l cysteine peptidase 0.1094 0.1139 0.1139
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0113 0.01 0.3079
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0005 0.0013
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.017 0.016 0.0972
Brugia malayi hypothetical protein 0.0019 0 0.0002
Mycobacterium ulcerans lipase LipD 0.0035 0.0017 0.0222
Onchocerca volvulus 0.0041 0.0023 0.02
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.017 0.016 0.1403
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0014 0.0014
Brugia malayi Cathepsin L-like precursor 0.0751 0.0775 0.3661
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0036 0.0019 0.0019
Plasmodium falciparum phosphatidylinositol 4-kinase 0.017 0.016 0.1403
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.011 0.0681
Loa Loa (eye worm) carboxylesterase 0.0251 0.0246 0.1161
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Loa Loa (eye worm) Csnk2b protein 0.0041 0.0024 0.0113
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0795 0.0821 0.388
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Entamoeba histolytica cysteine proteinase, putative 0.1094 0.1139 1
Entamoeba histolytica hypothetical protein 0.0076 0.006 0.053
Schistosoma mansoni cpg binding protein 0.0059 0.0042 0.02
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.008
Echinococcus granulosus serine protein kinase ATM 0.0458 0.0466 0.0466
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1485 0.1553 0.7336
Mycobacterium ulcerans pyruvate carboxylase 0.0318 0.0317 0.4971
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0007 0.0039
Plasmodium vivax serine-repeat antigen (SERA) 0.0247 0.0241 0.2115
Schistosoma mansoni lipoxygenase 0.008 0.0065 0.0308
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0318 0.0317 0.4971
Brugia malayi Csnk2b protein 0.0041 0.0024 0.0113
Trypanosoma brucei polo-like protein kinase 0.0231 0.0225 0.1386
Echinococcus multilocularis tumor protein p63 0.0383 0.0385 0.0385
Loa Loa (eye worm) hypothetical protein 0.0114 0.0101 0.0475
Onchocerca volvulus 0.0251 0.0246 0.2155
Brugia malayi follicle stimulating hormone receptor 0.0268 0.0263 0.1244
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0005 0.0042
Mycobacterium leprae Probable biotinylated protein homolog TB7.3 0.0029 0.0011 0.0244
Entamoeba histolytica cysteine protease, putative 0.0247 0.0241 0.2118
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0112 0.0675
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0318 0.0317 0.1496
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0231 0.0225 0.1061
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.0218 0.3409
Onchocerca volvulus 0.0048 0.003 0.0264
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Schistosoma mansoni hypothetical protein 0.0434 0.044 0.2079
Loa Loa (eye worm) phosphatidylinositol 3 0.017 0.016 0.0757
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0017 0.0222
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0247 0.0241 0.114
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0318 0.0317 0.1496
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0149 0.0138 0.0138
Schistosoma mansoni MAGUK homolog 0.0027 0.0008 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0247 0.0241 0.1491
Echinococcus granulosus high voltage activated calcium channel beta 0.0098 0.0084 0.0084
Echinococcus granulosus cathepsin L 0.0247 0.0241 0.0241
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0008 0.0047
Giardia lamblia Cathepsin B precursor 0.0795 0.0821 0.5063
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0251 0.0246 0.1161
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1094 0.1139 0.7043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0272 0.0268 0.1656
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Schistosoma mansoni lipoxygenase 0.0115 0.0102 0.0482
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0113 0.01 0.3079
Schistosoma mansoni hypothetical protein 0.0319 0.0318 0.1501
Brugia malayi PXA domain containing protein 0.0023 0.0005 0.0023
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0072 0.0056 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0017 0.0017
Trypanosoma brucei protein kinase, putative 0.0072 0.0056 0.0342
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0159 0.0982
Leishmania major cathepsin L-like protease 0.1094 0.1139 0.312
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.027 0.0266 0.1645
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0036 0.0019 0.0019
Leishmania major cathepsin L-like protease 0.1144 0.1192 0.3265
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0029 0.0011 0.003
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0987 0.1025 0.6338
Trypanosoma cruzi polo-like protein kinase, putative 0.0231 0.0225 0.0646
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.059 0.0605 0.2859
Entamoeba histolytica cysteine proteinase, putative 0.059 0.0605 0.5314
Loa Loa (eye worm) hypothetical protein 0.0319 0.0318 0.1501
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0014 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0113 0.01 0.0286
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.0055
Brugia malayi intermediate filament protein 0.003 0.0012 0.0057
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0036 0.0019 0.0087
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0458 0.0466 0.1341
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0828 0.0857 0.405
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0017 0.0082
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0008 0.0021
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0017 0.0446
Schistosoma mansoni gliotactin 0.0251 0.0246 0.1161
Toxoplasma gondii dihydrolipoamide acyltransferase, putative 0.0029 0.0011 0.0047
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0318 0.0317 0.4971
Trichomonas vaginalis PIKK family atypical protein kinase 0.0458 0.0466 0.2878
Mycobacterium leprae conserved hypothetical protein 0.017 0.016 0.5005
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0002 0.0017
Onchocerca volvulus 0.0059 0.0042 0.0367
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0032 0.0014 0.0039
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0828 0.0857 0.405
Brugia malayi cathepsin L-like cysteine proteinase 0.0247 0.0241 0.114
Echinococcus multilocularis cathepsin b 0.2018 0.2117 0.2117
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.051 0.052 0.3213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0489 0.0498 0.3076
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0159 0.0982
Echinococcus multilocularis musashi 0.003 0.0012 0.0012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0017 0.0017
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0828 0.0857 0.53
Onchocerca volvulus 0.0251 0.0246 0.2155
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0017 0.0222
Echinococcus multilocularis high voltage activated calcium channel beta 0.0098 0.0084 0.0084
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0017 0.0222
Schistosoma mansoni phosphatidylinositol 4-kinase 0.017 0.016 0.0757
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.027 0.0266 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0022 0.0103
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0428 0.0433 0.2679
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0015 0.0427
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0053 0.0328
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0251 0.0246 0.1161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0828 0.0857 0.5301
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0428 0.0433 0.2677
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.0072 0.0056 0.0344
Trichomonas vaginalis PIKK family atypical protein kinase 0.0828 0.0857 0.5301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0483 0.0492 0.3042
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0017 0.0017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2018 0.2117 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0247 0.0241 0.1464
Loa Loa (eye worm) pigment dispersing factor receptor c 0.011 0.0097 0.0457
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.027 0.0266 0.0766
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0231 0.0225 0.0225
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.1546 0.1617 0.4431
Echinococcus multilocularis expressed protein 0.0423 0.0428 0.0428
Entamoeba histolytica hypothetical protein 0.0022 0.0003 0.0027
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0318 0.0317 0.0867
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0773 0.0798 0.4936
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.008
Loa Loa (eye worm) hypothetical protein 0.017 0.016 0.0757
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0015 0.0074
Onchocerca volvulus Cathepsin L homolog 0.1094 0.1139 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0802 0.083 0.513
Entamoeba histolytica cysteine protease, putative 0.0247 0.0241 0.2118
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Schistosoma mansoni loxhd1 0.0019 0 0.0002
Brugia malayi Cathepsin L-like precursor 0.1094 0.1139 0.538
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1546 0.1617 0.4661
Echinococcus multilocularis transfer RNA-Lys 0.0041 0.0023 0.0023
Onchocerca volvulus Cathepsin F homolog 0.1094 0.1139 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0808 0.0835 0.5165
Giardia lamblia Cysteine protease 0.0247 0.0241 0.1464
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0268 0.0263 0.1244
Brugia malayi serine/threonine-protein kinase plk-2 0.0231 0.0225 0.1061
Loa Loa (eye worm) fibroinase 0.1094 0.1139 0.538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.0241 0.1491
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0032 0.0014 0.0039
Giardia lamblia Cathepsin B precursor 0.0795 0.0821 0.5063
Loa Loa (eye worm) RecQ helicase 0.0024 0.0005 0.0026
Mycobacterium tuberculosis Conserved hypothetical protein 0.017 0.016 0.2488
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0155 0.0733
Schistosoma mansoni hypothetical protein 0.0024 0.0006 0.0028
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0003 0.0003
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1466 0.1533 0.1533
Onchocerca volvulus 0.1094 0.1139 1
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0041 0.0024 0.0211
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.1546 0.1617 1
Trypanosoma brucei unspecified product 0.0209 0.0201 0.1242
Onchocerca volvulus 0.0251 0.0246 0.2155
Echinococcus multilocularis mitogen activated protein kinase 3 0.1546 0.1617 0.1617
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0251 0.0246 0.0246
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0007 0.0057
Trypanosoma cruzi cruzipain precursor, putative 0.0344 0.0344 0.099
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0053 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0247 0.0241 0.1491
Trypanosoma cruzi hypothetical protein, conserved 0.3295 0.3468 1
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0113 0.01 0.153
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0428 0.0433 0.2679
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0008 0.0047
Loa Loa (eye worm) hypothetical protein 0.0751 0.0775 0.3661
Brugia malayi Pre-SET motif family protein 0.0035 0.0017 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.003 0.0012 0.0076
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0036 0.0019 0.0019
Onchocerca volvulus 0.0751 0.0775 0.6803
Brugia malayi Cytochrome P450 family protein 0.0037 0.0019 0.0091
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0113 0.01 0.153
Echinococcus multilocularis carboxylesterase 5A 0.1485 0.1553 0.1553
Entamoeba histolytica Ran family GTPase 0.0024 0.0005 0.0046
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.027 0.0266 0.0766
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0003 0.0003
Leishmania major ATP-dependent phosphofructokinase 0.0123 0.011 0.0301
Trypanosoma cruzi cysteine peptidase, putative 0.1094 0.1139 0.3282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0808 0.0835 0.5165
Onchocerca volvulus 0.1094 0.1139 1
Entamoeba histolytica protein kinase domain containing protein 0.0072 0.0056 0.0491
Entamoeba histolytica cysteine protease, putative 0.0247 0.0241 0.2118
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.0835 0.0864 0.0864
Brugia malayi 6-phosphofructokinase 0.0123 0.011 0.0522
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0169 0.0159 0.0751
Entamoeba histolytica protein kinase rad3, putative 0.0442 0.0448 0.3933
Mycobacterium ulcerans hypothetical protein 0.0035 0.0017 0.0222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0782 0.0808 0.4994
Echinococcus granulosus voltage dependent calcium channel 0.0036 0.0019 0.0019
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0015 0.0094
Leishmania major cathepsin L-like protease 0.1094 0.1139 0.312
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0008 0.0047
Brugia malayi MAP kinase sur-1 0.1546 0.1617 0.7639
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.017 0.016 0.016
Toxoplasma gondii ABC1 family protein 0.0035 0.0017 0.0087
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0149 0.0138 0.0652
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.027 0.0266 0.1258
Echinococcus granulosus bloom syndrome protein 0.0024 0.0005 0.0005
Onchocerca volvulus 0.0056 0.0039 0.0342
Schistosoma mansoni hypothetical protein 0.0035 0.0017 0.008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.0241 0.114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0247 0.0241 0.1491
Echinococcus multilocularis serine protein kinase ATM 0.0458 0.0466 0.0466
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0247 0.0241 0.1491
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0017 0.0149
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.011 0.0097 0.0457
Plasmodium falciparum glycogen synthase kinase 3 0.0072 0.0056 0.0488
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1094 0.1139 0.7043
Giardia lamblia Hypothetical protein 0.0247 0.0241 0.1464
Schistosoma mansoni phosphatidylinositol 4-kinase 0.027 0.0266 0.1258
Echinococcus granulosus calcium activated potassium channel 0.002 0.0001 0.0001
Brugia malayi beta-lactamase 0.0035 0.0017 0.0082
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.003 0.0012 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0017 0.008
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0247 0.0241 0.114
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0829 0.0858 0.7532
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0247 0.0241 0.1491
Brugia malayi Carboxylesterase family protein 0.0251 0.0246 0.1161
Brugia malayi cathepsin F-like cysteine proteinase 0.0344 0.0344 0.1625
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0032 0.0014 0.0039
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0248 0.0242 0.1145
Onchocerca volvulus Cathepsin L homolog 0.1094 0.1139 1
Echinococcus granulosus para nitrobenzyl esterase 0.0251 0.0246 0.0246
Onchocerca volvulus 0.0072 0.0056 0.0488
Schistosoma mansoni cathepsin C 0.0247 0.0241 0.114
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0008 0.0047
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.059 0.0605 0.1743
Trichomonas vaginalis PIKK family atypical protein kinase 0.0802 0.083 0.513
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0149 0.0138 0.0138
Trichomonas vaginalis CMGC family protein kinase 0.1546 0.1617 1
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0113 0.01 0.0472
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0318 0.0317 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0761 0.0786 0.4858
Onchocerca volvulus 0.017 0.016 0.1403
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0319 0.0318 0.0318
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0017 0.0106
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0795 0.0821 0.2367
Brugia malayi hypothetical protein 0.0035 0.0017 0.0081
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0002
Schistosoma mansoni hypothetical protein 0.0035 0.0017 0.008
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0003 0.0015
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0724 0.0747 0.3527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0802 0.083 0.513
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0604 0.062 0.5439
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0037 0.0211
Onchocerca volvulus Serine\/threonine kinase homolog 0.0231 0.0225 0.1969
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.003 0.0012 0.0012
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Echinococcus multilocularis Zinc finger, PHD finger 0.027 0.0266 0.0266
Giardia lamblia Cathepsin L-like protease 0.0247 0.0241 0.1464
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.017 0.016 0.016
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0017 0.0222
Echinococcus granulosus ribosomal protein S6 kinase delta 1 0.0019 0.0001 0.0001
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0247 0.0241 0.2115
Plasmodium vivax vivapain-2 0.1094 0.1139 1
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0041 0.0024 0.0067
Entamoeba histolytica cysteine proteinase 2 0.059 0.0605 0.5314
Entamoeba histolytica phosphofructokinase, putative 0.0123 0.011 0.0969
Toxoplasma gondii preprocathepsin c precursor, putative 0.0247 0.0241 0.1474
Echinococcus multilocularis beta adrenergic receptor kinase 0.0039 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0787 0.0813 0.5029
Trichomonas vaginalis CMGC family protein kinase 0.1546 0.1617 1
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0027 0.0008 0.0008
Onchocerca volvulus 0.0035 0.0017 0.0149
Entamoeba histolytica hypothetical protein 0.0076 0.006 0.053
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.0057
Trypanosoma brucei cysteine peptidase C (CPC) 0.0795 0.0821 0.5077
Loa Loa (eye worm) hypothetical protein 0.0533 0.0544 0.2572
Leishmania major hypothetical protein, conserved 0.0054 0.0037 0.0101
Schistosoma mansoni fkbp-rapamycin associated protein 0.0442 0.0448 0.2116
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0113 0.01 0.0286
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Brugia malayi Cathepsin L-like precursor 0.1094 0.1139 0.538
Loa Loa (eye worm) hypothetical protein 0.0288 0.0285 0.1348
Echinococcus multilocularis 0.017 0.016 0.016
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0745 0.0769 0.4753
Echinococcus granulosus snurportin 1 0.0345 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0442 0.0448 0.2116
Schistosoma mansoni intermediate filament proteins 0.003 0.0012 0.0057
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0115 0.0102 0.0102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1094 0.1139 0.7043
Echinococcus granulosus beta-adrenergic receptor kinase 0.0039 0.0022 0.0022
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.0241 0.114
Giardia lamblia GTOR 0.0828 0.0857 0.5286
Echinococcus granulosus acetylcholinesterase 0.1485 0.1553 0.1553
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0149 0.0138 0.0652
Toxoplasma gondii cathepsin CPC1 0.0247 0.0241 0.1474
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0044 0.0273
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0 0.0002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.0241 0.114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0318 0.0317 0.4971
Loa Loa (eye worm) calcium channel 0.0036 0.0019 0.0087
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0247 0.0241 0.2115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0483 0.0492 0.3042
Loa Loa (eye worm) hypothetical protein 0.0344 0.0344 0.1625
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0795 0.0821 0.5079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Trichomonas vaginalis PIKK family atypical protein kinase 0.017 0.016 0.099
Echinococcus granulosus cathepsin l1 0.0751 0.0775 0.0775
Giardia lamblia Hypothetical protein 0.017 0.016 0.0962
Plasmodium vivax vivapain-3 0.059 0.0605 0.5312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.059 0.0605 0.3742
Schistosoma mansoni cpg binding protein 0.0062 0.0046 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0828 0.0857 0.5301
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.003 0.0012 0.0059
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0113 0.01 0.01
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0113 0.01 0.153
Brugia malayi Cathepsin L-like precursor 0.1094 0.1139 0.538
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Leishmania major cysteine peptidase A (CPA) 0.1094 0.1139 0.312
Giardia lamblia Cysteine protease 0.0247 0.0241 0.1464
Giardia lamblia Cathepsin L precursor 0.0247 0.0241 0.1464
Echinococcus granulosus geminin 0.037 0.0372 0.0372
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2018 0.2117 0.6102
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0037 0.0325
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0008 0.0047
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0008 0.0047
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0005 0.0026
Echinococcus granulosus Biotin lipoyl attachment 0.0029 0.0011 0.0011
Echinococcus multilocularis microtubule associated protein 2 0.0746 0.077 0.077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0782 0.0808 0.4994
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0015
Echinococcus multilocularis GPCR, family 2 0.0035 0.0017 0.0017
Entamoeba histolytica cysteine proteinase, putative 0.059 0.0605 0.5314
Schistosoma mansoni hypothetical protein 0.037 0.0372 0.1757
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0044 0.0273
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1094 0.1139 1
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0159 0.0982
Loa Loa (eye worm) hypothetical protein 0.0344 0.0344 0.1625
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0458 0.0466 0.2199
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.017 0.016 0.0757
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0828 0.0857 0.247
Entamoeba histolytica protein kinase domain containing protein 0.0169 0.0159 0.1396
Brugia malayi RNA, U transporter 1 0.0092 0.0077 0.0365
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.0835 0.0864 0.5333
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0039 0.0022 0.0103
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0052
Loa Loa (eye worm) phosphatidylinositol 3 0.0773 0.0798 0.3772
Loa Loa (eye worm) hypothetical protein 0.0385 0.0388 0.1831
Toxoplasma gondii CMGC kinase, CK2 family 0.0169 0.0159 0.0964
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0235 0.0229 0.1081
Plasmodium falciparum serine repeat antigen 3 0.0247 0.0241 0.2115
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0247 0.0241 0.2115
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.002
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0987 0.1025 0.8999
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.0345 0.163
Schistosoma mansoni aryl hydrocarbon receptor 0.0055 0.0038 0.0181
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0029 0.0011 0.0121
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0082
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0017 0.0222
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0053 0.0328
Loa Loa (eye worm) 6-phosphofructokinase 0.0123 0.011 0.0522
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0037 0.0325
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0042 0.02
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0003 0.0003
Echinococcus granulosus mitogen activated protein kinase 0.1546 0.1617 0.1617
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.017 0.016 0.0757
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0159 0.0982
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0017 0.0017
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0072 0.0056 0.0837
Entamoeba histolytica cysteine protease, putative 0.0247 0.0241 0.2118
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0165 0.0155 0.0733
Toxoplasma gondii target of rapamycin (TOR), putative 0.0802 0.083 0.512
Echinococcus granulosus expressed protein 0.0423 0.0428 0.0428
Giardia lamblia Kinase, PLK 0.0231 0.0225 0.1361
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0231 0.0225 0.0225
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0069 0.0053 0.0328
Mycobacterium tuberculosis Conserved protein 0.0035 0.0017 0.0222
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0442 0.0448 0.2116
Schistosoma mansoni serine/threonine protein kinase 0.0378 0.038 0.1795
Toxoplasma gondii pyruvate carboxylase 0.0318 0.0317 0.1942
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2018 0.2117 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0115 0.0102 0.0102
Echinococcus granulosus cyclin dependent kinase 19 0.0165 0.0155 0.0155
Plasmodium falciparum serine repeat antigen 4 0.0247 0.0241 0.2115
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0003 0.0003
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.017 0.016 0.046
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0015
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0112 0.1729
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0007 0.0033
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0123 0.011 0.3414
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0251 0.0246 0.1161
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.027 0.0266 0.0266
Plasmodium falciparum casein kinase 2, alpha subunit 0.0169 0.0159 0.1393
Trypanosoma brucei dihydrolipoamide branched chain transacylase, putative 0.0029 0.0011 0.0065
Toxoplasma gondii carbamoylphosphate synthetase 0.0072 0.0056 0.0327
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0005 0.0005
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1094 0.1139 0.1139
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0041 0.0024 0.0064
Mycobacterium ulcerans 6-phosphofructokinase 0.0123 0.011 0.1697
Loa Loa (eye worm) intermediate filament protein 0.003 0.0012 0.0057
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0014 0.0085
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0247 0.0241 0.114
Echinococcus multilocularis lamin dm0 0.003 0.0012 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0094
Toxoplasma gondii hypothetical protein 0.0048 0.0031 0.017
Trypanosoma cruzi cysteine peptidase, putative 0.0344 0.0344 0.099
Onchocerca volvulus 0.003 0.0012 0.0102
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1094 0.1139 0.1139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.0241 0.1491
Loa Loa (eye worm) hypothetical protein 0.2018 0.2117 1
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0069 0.0053 0.0326
Entamoeba histolytica cysteine proteinase, putative 0.1094 0.1139 1
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0007 0.0018
Toxoplasma gondii 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein 0.0029 0.0011 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0123 0.011 0.0682
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0029 0.0011 0.003
Schistosoma mansoni BC026374 protein (S09 family) 0.0251 0.0246 0.1161
Loa Loa (eye worm) phosphatidylinositol 3 0.017 0.016 0.0757
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.017 0.016 0.016
Schistosoma mansoni cathepsin B (C01 family) 0.0247 0.0241 0.114
Echinococcus granulosus importin subunit beta 1 0.0032 0.0014 0.0014
Echinococcus multilocularis mitogen activated protein kinase 0.1546 0.1617 0.1617
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0037 0.0228
Loa Loa (eye worm) hypothetical protein 0.0751 0.0775 0.3661
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0029 0.0011 0.003
Entamoeba histolytica protein kinase, putative 0.0072 0.0056 0.0491
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0072 0.0056 0.1476
Loa Loa (eye worm) phosphofructokinase 0.0123 0.011 0.0522
Schistosoma mansoni 6-phosphofructokinase 0.0123 0.011 0.0522
Leishmania major cathepsin L-like protease 0.1094 0.1139 0.312
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0014 0.0014
Brugia malayi hypothetical protein 0.0251 0.0246 0.1161
Onchocerca volvulus 0.0267 0.0263 0.2306
Onchocerca volvulus 0.0027 0.0008 0.0069
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0003 0.0015
Trichomonas vaginalis set domain proteins, putative 0.0267 0.0263 0.1625
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0112 0.1729
Leishmania major dihydrolipoamide acetyltransferase precursor, putative 0.0029 0.0011 0.0029
Trypanosoma cruzi cysteine proteinase, putative 0.059 0.0605 0.1743
Plasmodium falciparum cysteine proteinase falcipain 1 0.059 0.0605 0.5312
Trypanosoma cruzi target of rapamycin kinase 3 0.0808 0.0835 0.2407
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0072 0.0056 0.0152
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0036 0.0019 0.0087
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0072 0.0056 0.016
Leishmania major importin beta-1 subunit, putative 0.0026 0.0008 0.002
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0015 0.0134
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0023 0.0005 0.0043
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0247 0.0241 0.114
Echinococcus granulosus mitogen activated protein kinase 3 0.1546 0.1617 0.1617
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.0294 0.0847
Leishmania major phosphatidylinositol 4-kinase, putative 0.017 0.016 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1094 0.1139 0.7043
Echinococcus multilocularis cpg binding protein 0.0062 0.0046 0.0046
Plasmodium falciparum serine repeat antigen 8 0.0247 0.0241 0.2115
Giardia lamblia Cathepsin B precursor 0.0247 0.0241 0.1464
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0029 0.0011 0.0011
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1546 0.1617 0.4661
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0818 0.0846 0.2437
Entamoeba histolytica hypothetical protein 0.0022 0.0003 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0094
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0101 0.0087 0.041
Schistosoma mansoni hypothetical protein 0.0035 0.0017 0.008
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0015 0.0154
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0072 0.0056 0.0265
Trypanosoma cruzi cysteine proteinase, putative 0.059 0.0605 0.1743
Trichomonas vaginalis PIKK family atypical protein kinase 0.0536 0.0547 0.3385
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.027 0.0266 0.1629
Brugia malayi cathepsin Z-like cysteine proteinase 0.0247 0.0241 0.114
Schistosoma mansoni hypothetical protein 0.0092 0.0078 0.0368
Echinococcus granulosus intermediate filament protein 0.003 0.0012 0.0012
Onchocerca volvulus 0.0109 0.0095 0.0832
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.1546 0.1617 1
Onchocerca volvulus 0.0251 0.0246 0.2155
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0003 0.0015
Brugia malayi CXXC zinc finger family protein 0.0059 0.0042 0.02
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0052
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.017 0.016 0.0757
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0247 0.0241 0.2115
Entamoeba histolytica hypothetical protein 0.017 0.016 0.1407
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.9464 1 1
Echinococcus multilocularis cathepsin L 0.059 0.0605 0.0605
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0795 0.0821 0.225
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.027 0.0266 0.1629
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.059 0.0605 0.374
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0129 0.037
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0053 0.0328
Toxoplasma gondii ck2 beta subunit 0.0041 0.0024 0.0128
Echinococcus granulosus cysteine protease 0.059 0.0605 0.0605
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0318 0.0317 0.1956
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0005 0.0029
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0039 0.0186
Brugia malayi Cathepsin L-like precursor 0.0751 0.0775 0.3661
Leishmania major hypothetical protein, unknown function 0.017 0.016 0.0438
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0123 0.011 0.1697
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0082
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0005 0.0005
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0041 0.0024 0.0207
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0987 0.1025 0.6338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0751 0.0775 0.4792
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.003 0.0012 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0802 0.083 0.513
Trichomonas vaginalis conserved hypothetical protein 0.0319 0.0318 0.1964
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0987 0.1025 0.2954
Plasmodium falciparum carbamoyl phosphate synthetase 0.0072 0.0056 0.0489
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0094
Loa Loa (eye worm) carboxylesterase 0.0251 0.0246 0.1161
Loa Loa (eye worm) hypothetical protein 0.0721 0.0744 0.3514
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0019 0.0001 0.0005
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0017 0.0017
Onchocerca volvulus 0.003 0.0012 0.0102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1094 0.1139 0.7043
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0006 0.0006
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.1546 0.1617 0.4661
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0318 0.0317 0.4971
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0072 0.0056 0.0265
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0053 0.0152
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0082
Brugia malayi Carboxylesterase family protein 0.0251 0.0246 0.1161
Loa Loa (eye worm) hypothetical protein 0.0251 0.0246 0.1161
Loa Loa (eye worm) ctsf protein 0.1094 0.1139 0.538
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0017 0.008
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0113 0.01 0.0286
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0037 0.0106
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Entamoeba histolytica cysteine proteinase, putative 0.059 0.0605 0.5314
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1144 0.1192 0.737
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0072 0.0056 0.0264
Brugia malayi cathepsin B-like cysteine proteinase 0.2018 0.2117 1
Schistosoma mansoni rab6-interacting 0.0019 0 0.0002
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0047 0.003 0.0184
Trichomonas vaginalis casein kinase II beta chain, putative 0.0041 0.0024 0.0147
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.0241 0.114
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0005 0.0025
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0029 0.0011 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0247 0.0241 0.1491
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0003 0.0003
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0112 0.0306
Plasmodium falciparum lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 0.0029 0.0011 0.0093
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0017 0.0222
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.0068 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0782 0.0808 0.4994
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0808 0.0835 0.5164
Brugia malayi bHLH-PAS transcription factor 0.0041 0.0023 0.011
Schistosoma mansoni polycystin 1-related 0.0019 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0002
Leishmania major dihydrolipoamide acetyltransferase precursorlike protein 0.0029 0.0011 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0483 0.0492 0.3042
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0017 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0003 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0159 0.0982
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0014 0.0067
Plasmodium vivax dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative 0.0029 0.0011 0.0093
Echinococcus multilocularis cyclin dependent kinase 19 0.0165 0.0155 0.0155
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0053 0.0328
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0003 0.0018
Trypanosoma cruzi cysteine peptidase, putative 0.1144 0.1192 0.3435
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0318 0.0317 0.0317
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0099 0.0594
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0378 0.038 0.038
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0069 0.0053 0.0252
Leishmania major phosphatidylinositol 3-kinase, putative 0.0761 0.0786 0.2152
Brugia malayi Pre-SET motif family protein 0.0235 0.0229 0.1081
Loa Loa (eye worm) phosphatidylinositol 3 0.0258 0.0253 0.1196
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0003 0.0015
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0442 0.0448 0.129
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0761 0.0786 0.4857
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0003 0.0015
Echinococcus granulosus lamin dm0 0.003 0.0012 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.059 0.0605 0.5314
Echinococcus granulosus cathepsin L cysteine protease 0.059 0.0605 0.0605
Schistosoma mansoni microtubule-associated protein tau 0.0746 0.077 0.364
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0082
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0005 0.0025
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0041 0.0024 0.0211
Giardia lamblia Casein kinase II beta chain 0.0041 0.0024 0.0116
Entamoeba histolytica cysteine protease, putative 0.0247 0.0241 0.2118
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0008 0.0047
Echinococcus multilocularis para nitrobenzyl esterase 0.0251 0.0246 0.0246
Entamoeba histolytica cysteine protease, putative 0.059 0.0605 0.5314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0808 0.0835 0.5165
Leishmania major cytochrome p450-like protein 0.0025 0.0007 0.0017
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0017 0.0017
Brugia malayi phosphofructokinase 0.0123 0.011 0.0522
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0036 0.0019 0.0019
Schistosoma mansoni rab6-interacting 0.0019 0 0.0002
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0053 0.0152
Brugia malayi hypothetical protein 0.0022 0.0003 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0017 0.008
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0169 0.0159 0.1393
Onchocerca volvulus 0.0114 0.01 0.0878
Brugia malayi beta-lactamase family protein 0.0035 0.0017 0.0082
Trypanosoma cruzi casein kinase II, putative 0.0169 0.0159 0.0457
Trypanosoma brucei pyruvate dehydrogenase complex E3 binding protein, putative 0.0029 0.0011 0.0065
Plasmodium falciparum casein kinase II beta chain 0.0041 0.0024 0.0207
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0378 0.038 0.1795
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0003 0.0003
Echinococcus granulosus tumor protein p63 0.0383 0.0385 0.0385
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0015 0.0094
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0247 0.0241 0.2115
Giardia lamblia Cathepsin L precursor 0.0247 0.0241 0.1464
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0828 0.0857 0.0857
Entamoeba histolytica hypothetical protein 0.017 0.016 0.1407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0808 0.0835 0.5165
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0251 0.0246 0.3846
Brugia malayi hypothetical protein 0.0076 0.006 0.0285
Brugia malayi SH2 domain containing protein 0.0385 0.0388 0.1831
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0231 0.0225 0.0614
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0017 0.0082
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0247 0.0241 0.2115
Schistosoma mansoni hypothetical protein 0.0035 0.0017 0.008
Entamoeba histolytica cysteine protease, putative 0.0247 0.0241 0.2118
Echinococcus granulosus protein kinase shaggy 0.0072 0.0056 0.0056
Brugia malayi Cathepsin L-like precursor 0.0344 0.0344 0.1625

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 0.13 ug ml-1 Antimycobacterial activity against Mycobacterium tuberculosis H37Rv under aerobic condition ChEMBL. 20483615
MIC (functional) = 0.13 ug ml-1 Antimycobacterial activity against Mycobacterium tuberculosis H37Rv under dormancy-inducing hypoxic condition ChEMBL. 20483615

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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