Detailed information for compound 138375

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 469.616 | Formula: C27H39N3O4
  • H donors: 2 H acceptors: 4 LogP: 0.38 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CC1Cc2cc(ccc2CN(C1=O)C1CCCCC1)C(=O)N(CCC1CCNCC1)C
  • InChi: 1S/C27H39N3O4/c1-29(14-11-19-9-12-28-13-10-19)26(33)20-7-8-21-18-30(24-5-3-2-4-6-24)27(34)23(17-25(31)32)16-22(21)15-20/h7-8,15,19,23-24,28H,2-6,9-14,16-18H2,1H3,(H,31,32)
  • InChiKey: HUIGGCYPYURGFA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) No references
Homo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni integrin beta subunit Get druggable targets OG5_127959 All targets in OG5_127959
Brugia malayi Integrin beta pat-3 precursor Get druggable targets OG5_127959 All targets in OG5_127959
Loa Loa (eye worm) integrin alpha pat-2 Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) integrin beta-2 Get druggable targets OG5_127959 All targets in OG5_127959
Echinococcus granulosus integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum ko:K06464 integrin beta 2, putative Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma japonicum Integrin beta-PS precursor, putative Get druggable targets OG5_127959 All targets in OG5_127959
Echinococcus granulosus integrin beta 2 Get druggable targets OG5_127959 All targets in OG5_127959
Echinococcus multilocularis integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum Integrin beta-3 precursor, putative Get druggable targets OG5_127959 All targets in OG5_127959
Brugia malayi Integrin alpha pat-2 precursor Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus multilocularis integrin beta 2 Get druggable targets OG5_127959 All targets in OG5_127959
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum ko:K06476 integrin alpha 2B, putative Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma mansoni integrin alpha Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum IPR013513,Integrin alpha chain, C-terminal cytoplasmic region,domain-containing Get druggable targets OG5_129341 All targets in OG5_129341
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Probable ClpP-like protease 0.0332 0.1556 0.153
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0075 0.0257 0.0636
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0114 0.0452 0.0568
Echinococcus granulosus regulator of G protein signaling 3 0.0064 0.02 0.0324
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0152 0.0647 0.0746
Mycobacterium ulcerans acetyl-CoA synthetase 0.0045 0.0103 0.0023
Plasmodium falciparum importin beta, putative 0.0085 0.0307 0.0716
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0056 0.0159 0.0186
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.1302 0.1274
Schistosoma mansoni hypothetical protein 0.0095 0.0359 0.0359
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0056 0.0159 0.036
Echinococcus multilocularis integrin alpha ps 0.0083 0.0295 0.0353
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0179 0.0147
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0094 0.035 0.0348
Toxoplasma gondii phosphofructokinase domain-containing protein 0.006 0.0179 0.0375
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0119 0.0478 0.0478
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0332 0.1556 0.4113
Entamoeba histolytica recQ family helicase, putative 0.0041 0.0085 0.0152
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0045 0.0103 0.016
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0065 0.0207 0.0176
Trypanosoma cruzi importin beta-1 subunit, putative 0.0069 0.0226 0.0547
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0491 0.0586
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0056 0.0159 0.008
Echinococcus multilocularis glutamate synthase 0.0056 0.0159 0.0191
Mycobacterium ulcerans glutaminase 0.2001 1 1
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0036 0.006 0.003
Echinococcus multilocularis Chromo domain 0.0036 0.006 0.0072
Trypanosoma cruzi small ubiquitin protein, putative 0.0035 0.0055 0.0066
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0877 0.0877
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0282 0.1302 0.2108
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0175 0.0365
Giardia lamblia Sentrin 0.0035 0.0055 0.0066
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0097 0.0368 0.091
Trypanosoma brucei DNA polymerase IV, putative 0.0515 0.2483 0.6899
Leishmania major DNA polymerase kappa, putative 0.0125 0.0509 0.1311
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0055 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0198 0.0877 0.1421
Echinococcus granulosus dna polymerase kappa 0.0515 0.2483 0.402
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0065 0.0207 0.0176
Giardia lamblia UBC3 0.01 0.0383 0.0991
Trypanosoma brucei ubiquitin-conjugating enzyme E2, putative 0.01 0.0383 0.0953
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0839 0.0809
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0102 0.0394 0.1022
Brugia malayi CHD4 protein 0.004 0.008 0.005
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0175 0.0206
Schistosoma mansoni 6-phosphofructokinase 0.0221 0.0995 0.0995
Echinococcus multilocularis jumonji domain containing protein 0.0172 0.0749 0.0895
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0098 0.0374 0.0447
Plasmodium falciparum SUMO-conjugating enzyme UBC9 0.01 0.0383 0.0931
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.121 0.5999 0.5999
Treponema pallidum exodeoxyribonuclease (exoA) 0.0081 0.0286 0.0552
Schistosoma mansoni regulator of G protein signaling 0.0064 0.02 0.02
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0056 0.0159 0.0191
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.01 0.0383 0.0991
Echinococcus granulosus potassium voltage gated channel subfamily KQT 0.0129 0.0528 0.0855
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.0058
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0257 0.0226
Brugia malayi hypothetical protein 0.0485 0.2331 0.2308
Trichomonas vaginalis esterase, putative 0.004 0.008 0.0049
Loa Loa (eye worm) beta-lactamase 0.004 0.008 0.0078
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0394 0.0364
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0103 0.0023
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0058 0.0171 0.0353
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.1387 0.6894 0.8978
Echinococcus multilocularis regulator of G protein signaling 3 0.0064 0.02 0.0239
Brugia malayi hypothetical protein 0.0507 0.244 0.2417
Loa Loa (eye worm) heterochromatin protein 1 0.0222 0.0999 0.0997
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0065 0.0204 0.0423
Leishmania major DNA polymerase kappa, putative 0.0431 0.2056 0.5691
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.02 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0306 0.1423 0.3899
Brugia malayi RNA, U transporter 1 0.0242 0.1101 0.1074
Echinococcus granulosus polybromo 1 0.0035 0.0051 0.0083
Toxoplasma gondii selenide, water dikinase 0.0056 0.0159 0.032
Echinococcus granulosus chromobox protein 2 0.0036 0.006 0.0097
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0056 0.0159 0.036
Brugia malayi acetyltransferase, GNAT family protein 0.0745 0.3644 0.3624
Trypanosoma brucei hypothetical protein, conserved 0.0056 0.0159 0.032
Plasmodium falciparum thioredoxin reductase 0.0211 0.0943 0.2519
Loa Loa (eye worm) apoptosis regulator protein 0.0095 0.0359 0.0356
Schistosoma mansoni hypothetical protein 0.0056 0.0159 0.0159
Toxoplasma gondii PHD-finger domain-containing protein 0.0124 0.0503 0.1294
Schistosoma mansoni hypothetical protein 0.0124 0.0503 0.0503
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0257 0.0226
Entamoeba histolytica phosphofructokinase, putative 0.0221 0.0995 0.2717
Entamoeba histolytica acyl-CoA synthetase, putative 0.0152 0.0647 0.1736
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0096 0.0361 0.0892
Echinococcus granulosus ubiquitin conjugating enzyme e2 i 0.01 0.0383 0.062
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0103 0.0072
Brugia malayi ThiF family protein 0.0065 0.0204 0.0174
Loa Loa (eye worm) hypothetical protein 0.003 0.0031 0.0028
Toxoplasma gondii ThiF family protein 0.0065 0.0204 0.0446
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0056 0.0159 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0506 0.0476
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0286 0.0255
Entamoeba histolytica thioredoxin reductase, putative 0.0056 0.0159 0.036
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.008 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.006 0.0029
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0056 0.0159 0.0258
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0056 0.0159 0.036
Leishmania major 4-coumarate:coa ligase-like protein 0.0152 0.0647 0.1702
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.01 0.0383 0.0953
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.008 0.0049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0096 0.0065
Loa Loa (eye worm) hypothetical protein 0.0056 0.0159 0.0157
Trypanosoma brucei hypothetical protein, conserved 0.0125 0.0509 0.1311
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.006 0.0179 0.0244
Echinococcus multilocularis sodium channel protein 0.022 0.0992 0.1186
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0211 0.0943 0.2569
Brugia malayi Integrin alpha cytoplasmic region family protein 0.014 0.0583 0.0554
Leishmania major hypothetical protein, conserved 0.0054 0.0152 0.0299
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0081 0.0286 0.0717
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0053 0.0143 0.0165
Loa Loa (eye worm) hypothetical protein 0.0129 0.0528 0.0526
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0403 0.1915 0.3102
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0065 0.0205 0.0202
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0155 0.066 0.0631
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.1302 0.1274
Schistosoma mansoni amyloid beta A4 protein related 0.0216 0.0969 0.0969
Echinococcus multilocularis beta adrenergic receptor kinase 0.0065 0.0205 0.0245
Entamoeba histolytica hypothetical protein 0.0036 0.006 0.008
Schistosoma mansoni hypothetical protein 0.0095 0.0359 0.0359
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0116 0.0188
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0114 0.0455 0.1234
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0314 0.1465 0.4018
Loa Loa (eye worm) hypothetical protein 0.0085 0.0307 0.0305
Onchocerca volvulus 0.0118 0.0474 0.0705
Toxoplasma gondii histone lysine methyltransferase SET1 0.0086 0.0314 0.0757
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0081 0.0286 0.0679
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0045 0.0103 0.02
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0226 0.0195
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0789 0.076
Toxoplasma gondii hypothetical protein 0.0098 0.0374 0.0928
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0045 0.0103 0.02
Trichomonas vaginalis dullard protein, putative 0.0065 0.0207 0.0176
Plasmodium vivax JmjC domain containing protein 0.0058 0.0171 0.0437
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0595 0.2889 0.4678
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0257 0.0636
Trichomonas vaginalis 6-phosphofructokinase, putative 0.006 0.0179 0.0147
Echinococcus granulosus MAM 0.0033 0.0042 0.0068
Treponema pallidum NADH oxidase 0.0211 0.0943 0.2436
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0164 0.0708 0.0902
Schistosoma mansoni bromodomain containing protein 0.0025 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0485 0.2331 0.2329
Schistosoma mansoni apoptosis regulator bax 0.0095 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0045 0.0103 0.01
Schistosoma mansoni glutamate synthase 0.0056 0.0159 0.0159
Onchocerca volvulus 0.0045 0.0103 0.0115
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0152 0.0647 0.0572
Brugia malayi Disco-interacting protein 2 homolog 0.0118 0.0474 0.0445
Mycobacterium ulcerans acyl-CoA synthetase 0.0152 0.0647 0.0572
Plasmodium vivax phosphoglycerate kinase, putative 0.0732 0.3578 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0206 0.0203
Trypanosoma cruzi hypothetical protein, conserved 0.0125 0.0509 0.1347
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.0058
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0431 0.2056 0.2662
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0425 0.2024 0.5619
Loa Loa (eye worm) hypothetical protein 0.0058 0.0171 0.0169
Echinococcus granulosus axis inhibition protein axin 0.0064 0.02 0.0324
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0332 0.1556 0.186
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.1302 0.1274
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0103 0.0023
Loa Loa (eye worm) acetyltransferase 0.0745 0.3644 0.3642
Plasmodium falciparum acyl-CoA synthetase 0.0114 0.0452 0.1128
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0336 0.1578 0.4362
Echinococcus multilocularis axis inhibition protein axin 0.0064 0.02 0.0239
Onchocerca volvulus Huntingtin homolog 0.0142 0.0597 0.09
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0275 0.1268 0.1266
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0211 0.0943 0.2538
Loa Loa (eye worm) hypothetical protein 0.0332 0.1556 0.1554
Loa Loa (eye worm) hypothetical protein 0.0045 0.0103 0.01
Loa Loa (eye worm) hypothetical protein 0.0142 0.0597 0.0594
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0081 0.0286 0.0284
Echinococcus multilocularis importin subunit beta 1 0.0085 0.0307 0.0367
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0056 0.0159 0.0191
Echinococcus granulosus amyloid beta A4 protein 0.0216 0.0969 0.1569
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0513 0.2473 0.2956
Mycobacterium ulcerans hypothetical protein 0.0152 0.0647 0.0572
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0175 0.0175
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0061 0.0183 0.047
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0056 0.0159 0.0128
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0041 0.0085 0.0196
Onchocerca volvulus 0.0045 0.0103 0.0115
Trypanosoma cruzi polo-like protein kinase, putative 0.0282 0.1302 0.3582
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0282 0.1302 0.3555
Loa Loa (eye worm) hypothetical protein 0.0079 0.0278 0.0276
Mycobacterium tuberculosis Conserved hypothetical protein 0.0403 0.1915 0.2478
Entamoeba histolytica hypothetical protein 0.0064 0.02 0.0474
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0096 0.0361 0.093
Giardia lamblia DINP protein human, muc B family 0.0431 0.2056 0.5709
Echinococcus granulosus integrin alpha 3 0.0142 0.0593 0.096
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0343 0.1612 0.1927
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0732 0.3578 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0017 0.002
Echinococcus granulosus polycomb protein SCMH1 0.0301 0.1401 0.2268
Echinococcus multilocularis jumonji domain containing 1A 0.0058 0.0171 0.0204
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0054 0.0151 0.0151
Schistosoma mansoni glutamate synthase 0.0056 0.0159 0.0159
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0119 0.0478 0.0478
Loa Loa (eye worm) MBCTL1 0.0343 0.1612 0.161
Schistosoma mansoni blooms syndrome DNA helicase 0.0129 0.0528 0.0528
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0097 0.0368 0.091
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.006 0.0029
Echinococcus granulosus dnaJ subfamily B 0.0448 0.2143 0.3471
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.1268 0.124
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.121 0.5999 0.9714
Loa Loa (eye worm) hypothetical protein 0.0301 0.1401 0.1399
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0056 0.0159 0.032
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0732 0.3578 0.3557
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0081 0.0286 0.0717
Loa Loa (eye worm) hypothetical protein 0.0129 0.0528 0.0526
Trichomonas vaginalis phosphofructokinase, putative 0.0221 0.0995 0.0967
Echinococcus granulosus peregrin 0.0145 0.0609 0.0987
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0513 0.2473 0.2956
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.01 0.0383 0.0991
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0129 0.0528 0.0526
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0332 0.1556 0.4113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0181 0.0791 0.0791
Echinococcus multilocularis 0.0065 0.0207 0.0248
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0095 0.0359 0.0329
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0065 0.0207 0.0456
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1119 0.5539 0.5538
Echinococcus granulosus endonuclease exonuclease phosphatase 0.1204 0.5966 0.9661
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0041 0.0081 0.0099
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0058 0.0171 0.0393
Echinococcus granulosus voltage dependent calcium channel 0.0513 0.2473 0.4004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.1578 0.1552
Leishmania major acetyl-CoA synthetase, putative 0.0045 0.0103 0.016
Loa Loa (eye worm) RGS-3 protein 0.0064 0.02 0.0198
Echinococcus multilocularis L aminoadipate semialdehyde 0.0188 0.0826 0.0987
Loa Loa (eye worm) PHD-finger family protein 0.0124 0.0503 0.0501
Brugia malayi jmjC domain containing protein 0.0058 0.0171 0.0141
Loa Loa (eye worm) hypothetical protein 0.0188 0.0826 0.0824
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.1578 0.1552
Schistosoma mansoni hypothetical protein 0.0698 0.341 0.341
Leishmania major mitochondrial DNA polymerase beta 0.0682 0.3326 0.9286
Trypanosoma brucei DNA polymerase kappa, putative 0.0515 0.2483 0.6899
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0175 0.0284
Brugia malayi Integrin alpha pat-2 precursor 0.0185 0.0811 0.0783
Loa Loa (eye worm) hypothetical protein 0.004 0.008 0.0078
Entamoeba histolytica hypothetical protein 0.0103 0.0396 0.1028
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.1302 0.1274
Brugia malayi regulator of G-protein signaling egl-10 0.0064 0.02 0.017
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.1204 0.5966 0.7132
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0205 0.0205
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0114 0.0452 0.0375
Echinococcus granulosus axis inhibition protein axin 0.0064 0.02 0.0324
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0056 0.0159 0.008
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0058 0.0171 0.0353
Trichomonas vaginalis set domain proteins, putative 0.1274 0.632 0.6309
Leishmania major hypothetical protein, conserved 0.0056 0.0159 0.032
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0103 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0789 0.076
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0425 0.2024 0.2024
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0095 0.0359 0.0356
Plasmodium falciparum DNA repair protein REV1, putative 0.0125 0.0509 0.1289
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0061 0.0183 0.0183
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0017 0.0017
Toxoplasma gondii transporter, cation channel family protein 0.0111 0.0439 0.1113
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0051 0.0019
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0211 0.0943 0.2538
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0732 0.3578 1
Onchocerca volvulus Alhambra homolog 0.0124 0.0503 0.0752
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0211 0.0943 0.2538
Loa Loa (eye worm) hypothetical protein 0.0064 0.02 0.0198
Schistosoma mansoni lozenge 0.0061 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0098 0.037 0.0368
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0045 0.0103 0.0023
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0211 0.0943 0.0869
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0065 0.0204 0.0204
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.008 0.0096
Brugia malayi Importin beta-1 subunit 0.0085 0.0307 0.0277
Echinococcus multilocularis chromobox protein 2 0.0036 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0181 0.0791 0.0789
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0152 0.0275
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0119 0.0478 0.0478
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0171 0.0169
Brugia malayi hypothetical protein 0.0035 0.0054 0.0024
Echinococcus granulosus Chromo domain 0.0036 0.006 0.0097
Trichomonas vaginalis chromobox protein, putative 0.0036 0.006 0.0029
Toxoplasma gondii 6-phosphofructokinase 0.006 0.0179 0.0375
Echinococcus granulosus phosphatidylinositol phosphate 5 kinase type III 0.0097 0.0368 0.0596
Schistosoma mansoni phosphatidylserine receptor 0.0058 0.0171 0.0171
Echinococcus granulosus geminin 0.0698 0.341 0.5522
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0425 0.2024 0.242
Loa Loa (eye worm) pip kinase 2 0.121 0.5999 0.5998
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0117 0.0467 0.1229
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0097 0.0368 0.0948
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0103 0.0072
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0045 0.0103 0.0112
Loa Loa (eye worm) hypothetical protein 0.0044 0.01 0.0098
Toxoplasma gondii NADPH-glutathione reductase 0.0211 0.0943 0.2538
Brugia malayi PHD-finger family protein 0.0045 0.0102 0.0071
Mycobacterium ulcerans 6-phosphofructokinase 0.0221 0.0995 0.0922
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0065 0.0205 0.0174
Schistosoma mansoni sex comb on midleg homolog 0.0301 0.1401 0.1401
Entamoeba histolytica serine/threonine protein kinase, putative 0.0282 0.1302 0.3582
Schistosoma mansoni 6-phosphofructokinase 0.0221 0.0995 0.0995
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.008 0.0078
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0682 0.3326 0.9289
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0188 0.0826 0.0798
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.006 0.0179 0.0414
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0134 0.0554 0.0832
Schistosoma mansoni serine/threonine protein kinase 0.0282 0.1302 0.1302
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.006 0.0179 0.0102
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0161 0.0692 0.1827
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0097 0.0368 0.0337
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0056 0.0159 0.008
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0051 0.002
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0064 0.02 0.02
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0211 0.0943 0.2603
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0211 0.0943 0.2569
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0103 0.0023
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0097 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.015 0.0633 0.0631
Mycobacterium ulcerans acyl-CoA synthetase 0.0152 0.0647 0.0572
Loa Loa (eye worm) bromodomain containing protein 0.0039 0.0071 0.0069
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0211 0.0943 0.2538
Schistosoma mansoni DNA helicase recq1 0.0084 0.0303 0.0303
Leishmania major 4-coumarate:coa ligase-like protein 0.0152 0.0647 0.1702
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0045 0.0103 0.0112
Echinococcus multilocularis geminin 0.0698 0.341 0.4076
Schistosoma mansoni jumonji/arid domain-containing protein 0.0222 0.1001 0.1001
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0056 0.0159 0.0191
Echinococcus granulosus beta-adrenergic receptor kinase 0.0065 0.0205 0.0331
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0211 0.0943 0.2327
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0164 0.0708 0.0633
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.008 0.0082
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0269 0.1235 0.3394
Trichomonas vaginalis ubiquitin-conjugating enzyme rad6, putative 0.01 0.0383 0.0352
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0197 0.0875 0.0875
Trypanosoma brucei DNA polymerase kappa, putative 0.0515 0.2483 0.6899
Schistosoma mansoni phosphoglycerate kinase 0.0732 0.3578 0.3578
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0258 0.1179 0.1517
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.008 0.0048
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0332 0.1556 0.4113
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0119 0.0478 0.0572
Mycobacterium tuberculosis Conserved protein 0.004 0.008 0.0082
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0096 0.0065
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0097 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.004
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0064 0.02 0.0169
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0065 0.0207 0.0177
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0474 0.2276 0.2721
Brugia malayi Phosphoglycerate kinase 0.0732 0.3578 0.3558
Onchocerca volvulus 0.0036 0.006 0.0047
Plasmodium vivax glutathione reductase, putative 0.0608 0.2953 0.8247
Brugia malayi phosphofructokinase 0.0221 0.0995 0.0968
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.006 0.0029
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0341 0.1603 0.1916
Brugia malayi glutathione reductase 0.0608 0.2953 0.2931
Echinococcus granulosus integrin beta 2 0.028 0.1294 0.2096
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.1302 0.1274
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.008 0.005
Echinococcus multilocularis JmjC domain containing protein 4 0.0058 0.0171 0.0204
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0116 0.0188
Schistosoma mansoni jumonji domain containing protein 0.0391 0.1854 0.1854
Plasmodium falciparum phd finger protein, putative 0.0124 0.0503 0.1273
Mycobacterium ulcerans dehydrogenase 0.0056 0.0159 0.008
Loa Loa (eye worm) hypothetical protein 0.0102 0.0392 0.039
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0119 0.0478 0.0775
Mycobacterium leprae conserved hypothetical protein 0.0053 0.0143 0.0083
Toxoplasma gondii hypothetical protein 0.0114 0.0455 0.1157
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0513 0.2473 0.4004
Brugia malayi hypothetical protein 0.0064 0.02 0.017
Brugia malayi hypothetical protein 0.0057 0.0167 0.0137
Brugia malayi Associated with TFs and helicases family protein 0.0036 0.006 0.003
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0097 0.0368 0.091
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0045 0.0103 0.0029
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0244 0.0244
Trypanosoma brucei unspecified product 0.0487 0.2342 0.65
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0056 0.0159 0.0129
Loa Loa (eye worm) pip kinase 1 0.0097 0.0368 0.0366
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0097 0.0368 0.0948
Echinococcus multilocularis chromobox protein 1 0.0222 0.0999 0.1194
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0043 0.0094 0.0175
Trichomonas vaginalis chromobox protein, putative 0.0134 0.0554 0.0524
Loa Loa (eye worm) hypothetical protein 0.0058 0.0171 0.0169
Loa Loa (eye worm) hypothetical protein 0.0069 0.0226 0.0223
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0732 0.3578 0.3557
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.006 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0515 0.2483 0.6899
Loa Loa (eye worm) hypothetical protein 0.0065 0.0203 0.0201
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0056 0.0159 0.008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0161 0.0692 0.0692
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0152 0.0647 0.0572
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0053 0.0143 0.0064
Trypanosoma cruzi NADH dehydrogenase, putative 0.0056 0.0159 0.036
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.0058
Loa Loa (eye worm) hypothetical protein 0.0669 0.3263 0.3262
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0598 0.2901 0.8102
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.0582 0.0552
Loa Loa (eye worm) hypothetical protein 0.014 0.0583 0.0581
Brugia malayi jmjC domain containing protein 0.0222 0.1001 0.0974
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.022 0.0992 0.1606
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0079 0.0278 0.0247
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0036 0.006 0.0097
Echinococcus multilocularis polybromo 1 0.0035 0.0051 0.0061
Echinococcus multilocularis phosphoglycerate kinase 1 0.0732 0.3578 0.4277
Loa Loa (eye worm) hypothetical protein 0.004 0.008 0.0078
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0301 0.1401 0.1401
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0732 0.3578 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0079 0.0278 0.0278
Leishmania major DNA polymerase eta, putative 0.0669 0.3263 0.911
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.006 0.0029
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0084 0.0303 0.0362
Loa Loa (eye worm) hypothetical protein 0.0084 0.0303 0.03
Echinococcus granulosus disco interacting protein 2 0.0124 0.0505 0.0818
Trypanosoma brucei NADH dehydrogenase 0.0056 0.0159 0.032
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0598 0.2901 0.808
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0046 0.0041
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0081 0.0286 0.0207
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.0058
Schistosoma mansoni sex comb on midleg homolog 0.0301 0.1401 0.1401
Trichomonas vaginalis hypothetical protein 0.0036 0.006 0.0029
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0152 0.0647 0.0572
Schistosoma mansoni phosphoglycerate kinase 0.0732 0.3578 0.3578
Schistosoma mansoni glutamate synthase 0.0056 0.0159 0.0159
Treponema pallidum fructose-bisphosphate aldolase 0.0336 0.1578 0.4261
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0682 0.3326 0.9286
Loa Loa (eye worm) voltage-gated potassium channel 0.0281 0.13 0.1298
Loa Loa (eye worm) hypothetical protein 0.0208 0.0926 0.0924
Trypanosoma cruzi DNA polymerase kappa, putative 0.0515 0.2483 0.6912
Entamoeba histolytica phosphofructokinase, putative 0.0221 0.0995 0.2717
Trypanosoma brucei DNA polymerase kappa, putative 0.0515 0.2483 0.6899
Loa Loa (eye worm) hypothetical protein 0.0102 0.0394 0.0391
Trypanosoma brucei phosphoglycerate kinase 0.0732 0.3578 1
Brugia malayi Phosphoglycerate kinase 0.0269 0.1235 0.1208
Brugia malayi beta-lactamase family protein 0.004 0.008 0.005
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0152 0.0383
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0112 0.0445 0.1204
Schistosoma mansoni rotamase 0.0034 0.0051 0.0051
Entamoeba histolytica hypothetical protein 0.0341 0.1603 0.4431
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0097 0.0368 0.0948
Loa Loa (eye worm) jmjC domain-containing protein 0.0222 0.1001 0.0999
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.008 0.0082
Echinococcus granulosus Regulator of G protein signaling 20 0.0064 0.02 0.0324
Schistosoma mansoni hypothetical protein 0.0041 0.0081 0.0081
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0081 0.0286 0.0342
Loa Loa (eye worm) hypothetical protein 0.0152 0.0647 0.0645
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0045 0.0103 0.02
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0102 0.0394 0.0985
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0164 0.0708 0.0826
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0152 0.0339
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.1268 0.124
Onchocerca volvulus 0.0045 0.0103 0.0115
Loa Loa (eye worm) hypothetical protein 0.0114 0.0452 0.045
Echinococcus multilocularis dna polymerase kappa 0.0515 0.2483 0.2968
Schistosoma mansoni sulfide quinone reductase 0.0056 0.0159 0.0159
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0056 0.0159 0.0128
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0425 0.2024 0.3278
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0056 0.0159 0.0128
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.1268 0.124
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0275 0.1268 0.1241
Echinococcus granulosus L aminoadipate semialdehyde 0.0188 0.0826 0.1337
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0221 0.0995 0.2717
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0513 0.2473 0.2956
Treponema pallidum phosphoglycerate kinase 0.0732 0.3578 1
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0084 0.0303 0.0362
Echinococcus multilocularis ubiquitin specific protease 41 0.0075 0.0257 0.0308
Onchocerca volvulus 0.0098 0.037 0.0539
Schistosoma mansoni bromodomain containing protein 0.0093 0.0346 0.0346
Loa Loa (eye worm) ThiF family protein 0.0065 0.0204 0.0202
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0065 0.0204 0.0529
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0045 0.0103 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.006 0.0029
Schistosoma mansoni sulfide quinone reductase 0.0056 0.0159 0.0159
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0152 0.0647 0.0823
Echinococcus granulosus histone acetyltransferase MYST2 0.0343 0.1612 0.261
Trypanosoma cruzi NADH dehydrogenase, putative 0.0056 0.0159 0.036
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0299 0.139 0.2251
Echinococcus multilocularis bloom syndrome protein 0.0172 0.0745 0.0891
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0111 0.0436 0.1104
Echinococcus granulosus tumor protein p63 0.0351 0.1652 0.2676
Entamoeba histolytica recQ family DNA helicase 0.0043 0.0094 0.0175
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0045 0.0103 0.02
Echinococcus granulosus regulator of G protein signaling 3 0.0064 0.02 0.0324
Echinococcus multilocularis muscleblind protein 0.0155 0.0662 0.0791
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.02 0.0169
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0065 0.0204 0.033
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.1268 0.124
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0081 0.0286 0.0463
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0084 0.0303 0.0726
Echinococcus multilocularis Small ubiquitin modifier 2 0.0035 0.0055 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0515 0.2483 0.6899
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0065 0.0207 0.0176
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.008 0.0049
Loa Loa (eye worm) hypothetical protein 0.0047 0.0116 0.0114
Toxoplasma gondii hypothetical protein 0.0094 0.035 0.086
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0211 0.0943 0.1208
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0491 0.0794
Mycobacterium tuberculosis Conserved hypothetical protein 0.0359 0.1693 0.2188
Loa Loa (eye worm) hypothetical protein 0.0098 0.0374 0.0372
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0211 0.0943 0.2538
Trypanosoma brucei unspecified product 0.0278 0.1282 0.35
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0065 0.0207 0.0207
Loa Loa (eye worm) calcium channel 0.0513 0.2473 0.2471
Treponema pallidum thioredoxin reductase (trxB) 0.0056 0.0159 0.0189
Onchocerca volvulus 0.0134 0.0555 0.0834
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0056 0.0159 0.0191
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0732 0.3578 1
Chlamydia trachomatis thioredoxin reductase 0.0056 0.0159 0.0046
Toxoplasma gondii melibiase subfamily protein 0.0119 0.0478 0.1224
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.02 0.0169
Onchocerca volvulus 0.0507 0.244 0.3831
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0211 0.0943 0.2538
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0181 0.0791 0.0791
Onchocerca volvulus 0.0197 0.0875 0.1343
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0179 0.0147
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0056 0.0159 0.032
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0155 0.0153
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0065 0.0205 0.0202
Echinococcus granulosus lysine specific demethylase 6a 0.0058 0.0171 0.0277
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0097 0.0368 0.091
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0075 0.0257 0.0257
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0056 0.0159 0.0258
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0119 0.0478 0.0572
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.01 0.0383 0.0991
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0097 0.0368 0.0948
Loa Loa (eye worm) hypothetical protein 0.0043 0.0094 0.0092
Mycobacterium tuberculosis Conserved protein 0.004 0.008 0.0082
Schistosoma mansoni hypothetical protein 0.003 0.0031 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0125 0.0509 0.1347
Brugia malayi Pre-SET motif family protein 0.0161 0.0692 0.0663
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0046 0.0041
Echinococcus multilocularis integrin alpha 3 0.0142 0.0593 0.0708
Brugia malayi PHD-finger family protein 0.0049 0.0123 0.0092
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.004 0.008 0.013
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0056 0.0159 0.036
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1542 0.7678 1
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.121 0.5999 0.7171
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0299 0.139 0.139
Onchocerca volvulus 0.0049 0.0123 0.0147
Entamoeba histolytica phosphatidylinositol-4-phosphate 5-kinase, putative 0.0097 0.0368 0.0948
Plasmodium falciparum glutathione reductase 0.0608 0.2953 0.8227
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.01 0.0383 0.0953
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0431 0.2056 0.5691
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0181 0.0791 0.0945
Loa Loa (eye worm) hypothetical protein 0.0035 0.0051 0.0049
Brugia malayi hypothetical protein 0.0033 0.0042 0.0012
Loa Loa (eye worm) hypothetical protein 0.0124 0.0503 0.0501
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0036 0.006 0.0072
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.008 0.0082
Trichomonas vaginalis DNA helicase recq1, putative 0.0172 0.0745 0.0716
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0056 0.0159 0.0191
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0056 0.0159 0.0046
Schistosoma mansoni ubiquitin-conjugating enzyme E2 I 0.01 0.0383 0.0383
Schistosoma mansoni regulator of G protein signaling 0.0064 0.02 0.02
Trichomonas vaginalis chromobox protein, putative 0.0036 0.006 0.0029
Brugia malayi chromobox protein homolog 3 0.0124 0.0506 0.0477
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0075 0.0257 0.0597
Giardia lamblia Kinase, PLK 0.0282 0.1302 0.3582
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0108 0.0421 0.0527
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0175 0.0209
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0102 0.0394 0.0985
Plasmodium vivax DNA repair protein REV1, putative 0.0125 0.0509 0.1386
Schistosoma mansoni hypothetical protein 0.0341 0.1603 0.1603
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0269 0.1235 0.3394
Leishmania major hypothetical protein, conserved 0.0058 0.0171 0.0353
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0056 0.0159 0.0404
Plasmodium vivax small ubiquitin-related modifier, putative 0.0035 0.0055 0.0111
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0056 0.0159 0.0104
Brugia malayi 6-phosphofructokinase 0.0221 0.0995 0.0968
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0045 0.0103 0.0112
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.1387 0.6894 0.8978
Echinococcus multilocularis SAM and MBT domain containing protein 0.0301 0.1401 0.1675
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0403 0.1915 0.1915
Brugia malayi Regulator of G protein signaling domain containing protein 0.0064 0.02 0.017
Echinococcus multilocularis thioredoxin glutathione reductase 0.0611 0.2967 0.3547
Brugia malayi AF-10 protein 0.0041 0.0081 0.0051
Brugia malayi beta-lactamase family protein 0.004 0.008 0.005
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0513 0.2473 0.245
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.0582 0.0552
Trypanosoma cruzi trypanothione reductase, putative 0.0211 0.0943 0.2569
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0323 0.1509 0.4141
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0211 0.0943 0.2519
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0064 0.02 0.0198
Plasmodium vivax phosphatidylinositol-4-phosphate 5-kinase, putative 0.0097 0.0368 0.0989
Trichomonas vaginalis mercuric reductase, putative 0.0211 0.0943 0.0914
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.006 0.0179 0.0102
Schistosoma mansoni chromobox protein 0.0222 0.0999 0.0999
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.008 0.008
Echinococcus multilocularis histone acetyltransferase MYST2 0.0343 0.1612 0.1927
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0095 0.0359 0.0581
Brugia malayi serine/threonine-protein kinase plk-2 0.0282 0.1302 0.1275
Trypanosoma brucei unspecified product 0.0278 0.1282 0.35
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0103 0.0072
Plasmodium vivax SET domain protein, putative 0.0161 0.0692 0.1898
Trypanosoma cruzi polo-like protein kinase, putative 0.0282 0.1302 0.3582
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0045 0.0103 0.01
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0056 0.0159 0.032
Brugia malayi AMP-binding enzyme family protein 0.0152 0.0647 0.0619
Loa Loa (eye worm) hypothetical protein 0.0094 0.035 0.0348
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0119 0.0478 0.0478
Schistosoma mansoni peptidase Clp (S14 family) 0.0332 0.1556 0.1556
Echinococcus multilocularis GPCR, family 2 0.0047 0.0116 0.0139
Brugia malayi ThiF family protein 0.0098 0.0374 0.0345
Echinococcus granulosus transcription factor Dp 1 0.0246 0.112 0.1813
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0114 0.0455 0.1135
Trypanosoma brucei small ubiquitin-related modifier 0.0035 0.0055 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.1268 0.124
Echinococcus multilocularis ubiquitin conjugating enzyme e2 i 0.01 0.0383 0.0458
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0056 0.0159 0.0128
Trypanosoma brucei DNA polymerase kappa, putative 0.0515 0.2483 0.6899
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0732 0.3578 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0218 0.0977 0.1253
Loa Loa (eye worm) TK/ALK protein kinase 0.0033 0.0042 0.004
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0056 0.0158 0.0357
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0089 0.0325 0.0526
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.1302 0.1274
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0097 0.0368 0.0366
Schistosoma mansoni zinc finger protein 0.0043 0.0091 0.0091
Giardia lamblia Sgs1 DNA helicase, putative 0.0084 0.0303 0.0764
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0171 0.0169
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0045 0.0103 0.0072
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0064 0.02 0.02
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0098 0.0374 0.0374
Trypanosoma brucei DNA polymerase kappa, putative 0.0306 0.1423 0.3899
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0361 0.1704 0.4715
Trypanosoma brucei phosphoglycerate kinase 0.0269 0.1235 0.3366
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0056 0.0159 0.0258
Brugia malayi CXXC zinc finger family protein 0.0134 0.0555 0.0526
Echinococcus multilocularis integrin alpha ps 0.004 0.0077 0.0092
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0425 0.2024 0.2
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0069 0.0226 0.0195
Schistosoma mansoni transcription factor LCR-F1 0.0341 0.1603 0.1603
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0095 0.0359 0.0429
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0598 0.2901 0.2844
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0056 0.0159 0.032
Echinococcus granulosus expressed protein 0.1245 0.6175 1
Entamoeba histolytica hypothetical protein 0.0069 0.0226 0.0547
Trypanosoma brucei DNA polymerase kappa, putative 0.0431 0.2056 0.5691
Schistosoma mansoni hypothetical protein 0.0033 0.0042 0.0042
Schistosoma mansoni lipoxygenase 0.0121 0.0491 0.0491
Toxoplasma gondii PHD-finger domain-containing protein 0.0124 0.0503 0.1294
Brugia malayi hypothetical protein 0.0208 0.0926 0.0899
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0425 0.2024 0.5601
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0056 0.0159 0.0104
Echinococcus granulosus integrin alpha ps 0.004 0.0077 0.0125
Echinococcus granulosus cpg binding protein 0.0138 0.0576 0.0932
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0789 0.076
Schistosoma mansoni hypothetical protein 0.1848 0.9226 0.9226
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0089 0.0325 0.0389
Loa Loa (eye worm) hypothetical protein 0.004 0.008 0.0078
Echinococcus granulosus 6 phosphofructokinase 0.0221 0.0995 0.1612
Trichomonas vaginalis bromodomain-containing protein, putative 0.0221 0.0994 0.0965
Trichomonas vaginalis importin beta-1, putative 0.0069 0.0226 0.0195
Leishmania major DNA polymerase eta, putative 0.0392 0.1857 0.5129
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0097 0.0368 0.0948
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0095 0.0359 0.0359
Echinococcus granulosus regulator of G protein signaling 7 0.0064 0.02 0.0324
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0045 0.0103 0.0166
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0732 0.3578 0.4648
Echinococcus multilocularis expressed protein 0.0034 0.0051 0.006
Schistosoma mansoni hypothetical protein 0.0047 0.0116 0.0116
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0598 0.2901 0.3765
Loa Loa (eye worm) oxidoreductase 0.0045 0.0103 0.01
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0211 0.0943 0.2569
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0332 0.1556 0.1487
Treponema pallidum oxidoreductase 0.0056 0.0159 0.0189
Trichomonas vaginalis phosphofructokinase, putative 0.0221 0.0995 0.0967
Echinococcus multilocularis regulator of G protein signaling 7 0.0064 0.02 0.0239
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0116 0.0086
Echinococcus granulosus chromobox protein 1 0.0222 0.0999 0.1618
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0175 0.0096
Schistosoma mansoni polybromo-1 0.0035 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.0698 0.341 0.341
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0097 0.0368 0.0368
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0053 0.0143 0.0359
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0323 0.1509 0.4165
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0075 0.0257 0.0308
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0096 0.0065
Loa Loa (eye worm) hypothetical protein 0.0124 0.0506 0.0504
Onchocerca volvulus 0.0056 0.0159 0.0205
Entamoeba histolytica ubiquitin like protein 0.0035 0.0055 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0515 0.2483 0.6899
Treponema pallidum hypothetical protein 0.0598 0.2901 0.8059
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0056 0.0159 0.0296
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0282 0.1302 0.13
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.02 0.0169
Trichomonas vaginalis glutamate synthase, putative 0.0056 0.0159 0.0128
Loa Loa (eye worm) hypothetical protein 0.0732 0.3578 0.3576
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0155 0.0658 0.1066
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0152 0.0275
Brugia malayi mbt repeat family protein 0.0301 0.1401 0.1374
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.006 0.008
Echinococcus granulosus regulator of G protein signaling 7 0.0064 0.02 0.0324
Brugia malayi Ubiquitin-like protein SMT3 0.0035 0.0055 0.0025
Echinococcus multilocularis PHD finger protein rhinoceros 0.0124 0.0503 0.0602
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0211 0.0943 0.0915
Giardia lamblia Fructose-bisphosphate aldolase 0.0336 0.1578 0.4362
Echinococcus multilocularis cpg binding protein 0.0138 0.0576 0.0688
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0081 0.0286 0.0717
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0056 0.0159 0.036
Entamoeba histolytica phosphoinositide kinase, putative 0.0097 0.0368 0.0948
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0084 0.0303 0.049
Trypanosoma cruzi DNA polymerase kappa, putative 0.0515 0.2483 0.6912
Onchocerca volvulus 0.0152 0.0647 0.098
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0332 0.1556 0.1487
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0286 0.076
Schistosoma mansoni hypothetical protein 0.0047 0.0116 0.0116
Mycobacterium ulcerans DNA polymerase IV 0.0515 0.2483 0.2422
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0171 0.0169
Echinococcus granulosus JmjC domain containing protein 4 0.0058 0.0171 0.0277
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0392 0.1857 0.5129
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0056 0.0159 0.036
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0056 0.0159 0.0104
Schistosoma mansoni integrin alpha-ps 0.0043 0.0094 0.0094
Echinococcus granulosus bloom syndrome protein 0.0172 0.0745 0.1207
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0097 0.0368 0.0338
Loa Loa (eye worm) runx1 0.0061 0.0184 0.0182
Trichomonas vaginalis dullard protein, putative 0.0065 0.0207 0.0176
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0513 0.2473 0.2473
Schistosoma mansoni blooms syndrome DNA helicase 0.0043 0.0094 0.0094
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.006 0.0039
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0211 0.0943 0.1127
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0084 0.0303 0.03
Onchocerca volvulus Glucosylceramidase homolog 0.018 0.0789 0.1207
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0403 0.1915 0.229
Schistosoma mansoni kinase 0.0143 0.0601 0.0601
Toxoplasma gondii phosphofructokinase PFKII 0.006 0.0179 0.0375
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.006 0.0039
Trichomonas vaginalis DNA helicase recq, putative 0.0102 0.0394 0.0364
Onchocerca volvulus 0.004 0.008 0.0079
Leishmania major phosphoglycerate kinase B, cytosolic 0.0732 0.3578 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0515 0.2483 0.2459
Loa Loa (eye worm) hypothetical protein 0.0152 0.0647 0.0645
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0056 0.0159 0.0186
Trypanosoma cruzi trypanothione reductase, putative 0.0608 0.2953 0.8239
Echinococcus granulosus expressed protein 0.0034 0.0051 0.0082
Schistosoma mansoni axis inhibition protein axin 0.0064 0.02 0.02
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0299 0.139 0.1363
Toxoplasma gondii thioredoxin reductase 0.0608 0.2953 0.8231
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0079 0.0278 0.0278
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0064 0.02 0.0239
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0041 0.0081 0.0099
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0103 0.0396 0.1028
Schistosoma mansoni jumonji/arid domain-containing protein 0.0222 0.1001 0.1001
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0114 0.0455 0.0493
Brugia malayi SET domain containing protein 0.0043 0.0094 0.0063
Echinococcus multilocularis phosphatidylinositol phosphate 5 kinase type III 0.0097 0.0368 0.044
Leishmania major acetyl-CoA synthetase, putative 0.0045 0.0103 0.016
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0056 0.0159 0.0128
Toxoplasma gondii PHD-finger domain-containing protein 0.0041 0.0081 0.0099
Plasmodium vivax heterochromatin protein 1, putative 0.0036 0.006 0.0125
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0045 0.0103 0.0112
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0745 0.3644 0.3644
Trichomonas vaginalis glutaminase, putative 0.2001 1 1
Schistosoma mansoni hypothetical protein 0.0095 0.0359 0.0359
Schistosoma mansoni z-protein (S1r protein) 0.0064 0.02 0.02
Loa Loa (eye worm) mbt repeat family protein 0.0301 0.1401 0.1399
Schistosoma mansoni integrin alpha-ps 0.0083 0.0295 0.0295
Echinococcus granulosus GPCR family 2 0.0047 0.0116 0.0188
Entamoeba histolytica hypothetical protein 0.0036 0.006 0.008
Echinococcus multilocularis Protein lozenge 0.0061 0.0184 0.022
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0065 0.0207 0.0539
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0056 0.0159 0.0404
Echinococcus granulosus PHD finger protein rhinoceros 0.0124 0.0503 0.0815
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0096 0.0361 0.093
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0043 0.0094 0.0134
Plasmodium vivax hypothetical protein, conserved 0.004 0.008 0.0182
Loa Loa (eye worm) hypothetical protein 0.003 0.0031 0.0028
Loa Loa (eye worm) SMO-1 protein 0.0035 0.0055 0.0053
Giardia lamblia DNA damage repair protein 0.0125 0.0509 0.1347
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0789 0.076
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0257 0.0636
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0211 0.0943 0.2538
Echinococcus multilocularis lysine specific demethylase 5A 0.0218 0.0981 0.1173
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0065 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0051 0.0136 0.0134
Echinococcus granulosus jumonji domain containing protein 0.0172 0.0749 0.1213
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0045 0.0103 0.0112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0045 0.0103 0.0112
Trypanosoma brucei DNA damage repair protein, putative 0.0125 0.0509 0.1311
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0063 0.0196 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.004 0.008 0.0048
Plasmodium vivax hypothetical protein, conserved 0.0124 0.0503 0.137
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0129 0.0528 0.0631
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0221 0.0994 0.0965
Echinococcus granulosus Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0097 0.0368 0.0596
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0179 0.0147
Plasmodium falciparum thioredoxin reductase 0.0608 0.2953 0.8227
Brugia malayi ImpB/MucB/SamB family protein 0.0669 0.3263 0.3243
Entamoeba histolytica deoxycytidyl transferase, putative 0.0403 0.1915 0.5312
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0269 0.1235 0.3394
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0075 0.0257 0.0417
Plasmodium vivax acyl-CoA synthetase, putative 0.0114 0.0452 0.1226
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0207 0.0495
Schistosoma mansoni hypothetical protein 0.0033 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.121 0.5999 0.5998
Leishmania major ATP-dependent phosphofructokinase 0.0221 0.0995 0.2687
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.015 0.0633 0.0604
Echinococcus granulosus importin subunit beta 1 0.0085 0.0307 0.0497
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0211 0.0943 0.2603
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0114 0.0452 0.09
Loa Loa (eye worm) hypothetical protein 0.0231 0.1044 0.1042
Echinococcus granulosus glutamate synthase 0.0056 0.0159 0.0258
Trypanosoma brucei chrX additional, unordered contigs 0.0125 0.0509 0.1311
Echinococcus granulosus histone acetyltransferase KAT2B 0.0221 0.0994 0.161
Echinococcus multilocularis regulator of G protein signaling 3 0.0064 0.02 0.0239
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0682 0.3326 0.9289
Loa Loa (eye worm) phosphofructokinase 0.0221 0.0995 0.0993
Loa Loa (eye worm) hypothetical protein 0.0145 0.061 0.0608
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0096 0.0361 0.093
Mycobacterium ulcerans monoxygenase 0.0056 0.0159 0.008
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0221 0.0994 0.2684
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0097 0.0368 0.0948
Loa Loa (eye worm) FYVE zinc finger family protein 0.0097 0.0368 0.0366
Echinococcus multilocularis zinc finger protein 0.0043 0.0091 0.0109
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.008 0.013
Brugia malayi Bromodomain containing protein 0.0106 0.0414 0.0385
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0108 0.0421 0.0527
Brugia malayi AMP-binding enzyme family protein 0.0152 0.0647 0.0619
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0045 0.0103 0.016
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0058 0.0171 0.0171
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0036 0.006 0.0015
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0097 0.0368 0.091
Leishmania major hypothetical protein, conserved 0.0056 0.0159 0.032
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0152 0.0647 0.0823
Trypanosoma cruzi DNA polymerase kappa, putative 0.0515 0.2483 0.6912
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0084 0.0303 0.0726
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0877 0.0877
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0042 0.0091 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.1302 0.1274
Loa Loa (eye worm) hypothetical protein 0.0155 0.0662 0.0659
Echinococcus granulosus phd:f box containing protein 0.0058 0.0171 0.0277
Giardia lamblia Thioredoxin reductase 0.0056 0.0159 0.036
Trichomonas vaginalis chromobox protein, putative 0.0134 0.0554 0.0524
Echinococcus granulosus snurportin 1 0.0909 0.4475 0.7246
Echinococcus multilocularis muscleblind protein 1 0.0155 0.0662 0.0791
Trypanosoma brucei phosphoglycerate kinase, putative 0.0269 0.1235 0.3366
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0198 0.0877 0.1049
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0175 0.0145
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0061 0.0183 0.0363
Echinococcus granulosus muscleblind protein 0.0155 0.0662 0.1071
Leishmania major DNA damage repair protein, putative 0.0125 0.0509 0.1311
Echinococcus granulosus integrin alpha ps 0.0083 0.0295 0.0478
Loa Loa (eye worm) hypothetical protein 0.0045 0.0102 0.0099
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0053 0.0143 0.0064
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0299 0.139 0.1661
Brugia malayi hypothetical protein 0.0341 0.1603 0.1577
Schistosoma mansoni importin beta-1 0.0085 0.0307 0.0307
Mycobacterium ulcerans ferredoxin reductase 0.0056 0.0159 0.008
Mycobacterium tuberculosis Probable dehydrogenase 0.1387 0.6894 0.8978
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0198 0.0877 0.0849
Schistosoma mansoni phd/f-box containing protein 0.0058 0.0171 0.0171
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0745 0.3644 0.4356
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0211 0.0943 0.2327
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0159 0.036
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0045 0.0103 0.0029
Mycobacterium tuberculosis Probable oxidoreductase 0.1542 0.7678 1
Trichomonas vaginalis phosphofructokinase, putative 0.0221 0.0995 0.0967
Giardia lamblia DNA repair protein RAD52 0.0361 0.1704 0.4715
Trypanosoma cruzi DNA polymerase kappa, putative 0.0515 0.2483 0.6912
Mycobacterium ulcerans hypothetical protein 0.0359 0.1693 0.1626
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0161 0.0692 0.0827
Trichomonas vaginalis glutathione reductase, putative 0.0211 0.0943 0.0914
Loa Loa (eye worm) hypothetical protein 0.0075 0.0257 0.0255
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.006 0.0179 0.0351
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0188 0.0826 0.0826
Plasmodium vivax importin-beta 2, putative 0.0085 0.0307 0.0819
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1542 0.7678 1
Brugia malayi ImpB/MucB/SamB family protein 0.0403 0.1915 0.189
Loa Loa (eye worm) CHromoDomain protein family member 0.004 0.008 0.0078
Loa Loa (eye worm) hypothetical protein 0.0043 0.0094 0.0091
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.1578 0.1552
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0065 0.0207 0.0336
Loa Loa (eye worm) DOMON domain-containing protein 0.003 0.0031 0.0028
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0095 0.0359 0.0581
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0045 0.0103 0.016
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0064 0.02 0.02
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0045 0.0103 0.0029
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0116 0.0139
Brugia malayi jmjC domain containing protein 0.0058 0.0171 0.0141
Entamoeba histolytica hypothetical protein 0.0053 0.0143 0.0315
Schistosoma mansoni glutaminase 0.2001 1 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0282 0.1302 0.2021
Brugia malayi AMP-binding enzyme family protein 0.0152 0.0647 0.0619
Toxoplasma gondii small ubiquitin family modifier, putative 0.0035 0.0055 0.0024
Brugia malayi jmjC domain containing protein 0.0058 0.0171 0.0141
Trypanosoma brucei DNA polymerase kappa, putative 0.0515 0.2483 0.6899
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0211 0.0943 0.2327
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0789 0.076
Schistosoma mansoni hypothetical protein 0.0036 0.006 0.006
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0056 0.0159 0.0186
Brugia malayi jmjC domain containing protein 0.0058 0.0171 0.0141
Echinococcus multilocularis transcription factor Dp 1 0.0246 0.112 0.1338
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0152 0.0299
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.004
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0053 0.0143 0.0275
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0056 0.0159 0.0191
Plasmodium vivax ubiquitin activating enzyme, putative 0.0098 0.0374 0.1007
Plasmodium vivax 6-phosphofructokinase, putative 0.006 0.0179 0.0458
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0124 0.0505 0.0505
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0323 0.1509 0.4141
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0259 0.1189 0.3219
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0343 0.1612 0.261
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0221 0.0994 0.2684
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0257 0.0597
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0065 0.0207 0.0495
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.0058
Schistosoma mansoni DNA polymerase eta 0.0669 0.3263 0.3263
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0179 0.0147
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0045 0.0103 0.0023
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0065 0.0207 0.0176
Echinococcus multilocularis regulator of G protein signaling 0.0064 0.02 0.0239
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0789 0.076
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0056 0.0159 0.036
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0282 0.1302 0.1556
Brugia malayi Valyl-tRNA synthetase 0.0036 0.006 0.003
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0045 0.0103 0.0123
Brugia malayi Regulator of G protein signaling domain containing protein 0.0064 0.02 0.017
Brugia malayi Bloom's syndrome protein homolog 0.0172 0.0745 0.0717
Onchocerca volvulus 0.0051 0.0136 0.0168
Brugia malayi Muscleblind-like protein 0.0155 0.0662 0.0633
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0045 0.0103 0.0112
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0097 0.0368 0.091
Entamoeba histolytica disulphide oxidoreductase, putative 0.0056 0.0159 0.036
Echinococcus multilocularis integrin alpha ps 0.0083 0.0295 0.0353
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.008 0.0049
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0061 0.0183 0.0386
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0097 0.0368 0.0948
Loa Loa (eye worm) RecQ helicase 0.0172 0.0745 0.0743
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0332 0.1556 0.1942
Loa Loa (eye worm) 6-phosphofructokinase 0.0221 0.0995 0.0993
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.1578 0.1552
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0111 0.0439 0.0437
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0332 0.1556 0.4261
Mycobacterium ulcerans acyl-CoA synthetase 0.0152 0.0647 0.0572
Echinococcus granulosus ubiquitin specific protease 41 0.0075 0.0257 0.0417
Brugia malayi glutaminase DH11.1 0.2001 1 1
Echinococcus multilocularis disco interacting protein 2 0.0124 0.0505 0.0604
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.0307 0.0738
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0103 0.0023
Schistosoma mansoni hypothetical protein 0.004 0.0077 0.0077
Onchocerca volvulus 0.004 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0343 0.1612 0.161
Schistosoma mansoni voltage-gated cation channel 0.0513 0.2473 0.2473
Mycobacterium tuberculosis Probable reductase 0.1387 0.6894 0.8978
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0198 0.0877 0.1421
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0096 0.0065
Trichomonas vaginalis DNA helicase recq, putative 0.0172 0.0745 0.0716
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0221 0.0995 0.1277
Plasmodium falciparum histone acetyltransferase GCN5 0.02 0.0888 0.2365
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0211 0.0943 0.2519
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.02 0.0169
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0061 0.0183 0.0219
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0045 0.0103 0.0023
Plasmodium vivax acetyl-CoA synthetase, putative 0.0045 0.0103 0.0245
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0056 0.0159 0.036
Leishmania major hypothetical protein, conserved 0.0065 0.0207 0.0456
Brugia malayi Pip kinase protein 1 0.0097 0.0368 0.0338
Schistosoma mansoni hypothetical protein 0.0047 0.0116 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0211 0.0943 0.2569
Echinococcus granulosus dna polymerase eta 0.0669 0.3263 0.5285
Brugia malayi mbt repeat family protein 0.0301 0.1401 0.1374
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0103 0.0023
Mycobacterium ulcerans hypothetical protein 0.0125 0.0509 0.0432
Trichomonas vaginalis chromobox protein, putative 0.0222 0.0999 0.0971
Mycobacterium ulcerans phosphoglycerate kinase 0.0732 0.3578 0.3526
Entamoeba histolytica hypothetical protein 0.0341 0.1603 0.4431
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0086 0.0102
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0065 0.0207 0.0495
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0056 0.0159 0.0129
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0425 0.2024 0.2022
Trypanosoma brucei DNA polymerase IV, putative 0.0487 0.2342 0.65
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0089 0.0328 0.0328
Brugia malayi Pre-SET motif family protein 0.1119 0.5539 0.5525
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0124 0.0506 0.0756
Mycobacterium tuberculosis Conserved protein 0.004 0.008 0.0082
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0211 0.0943 0.2538
Trichomonas vaginalis antibiotic synthetase, putative 0.0045 0.0103 0.0071
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0175 0.0096
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.0058
Giardia lamblia Glutamate synthase 0.0056 0.0159 0.036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.1578 0.1552
Schistosoma mansoni protein phosphatase 2C 0.0058 0.0171 0.0171
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0179 0.0147
Loa Loa (eye worm) hypothetical protein 0.0064 0.02 0.0198
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0075 0.0257 0.0227
Onchocerca volvulus 0.0301 0.1401 0.2178
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0608 0.2953 0.3832
Trichomonas vaginalis antibiotic synthetase, putative 0.0045 0.0103 0.0071
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0098 0.0374 0.0906
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0084 0.0303 0.0273
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0332 0.1556 0.252
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0065 0.0207 0.0456
Echinococcus multilocularis dna polymerase eta 0.0669 0.3263 0.3901
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0056 0.0159 0.0186
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0056 0.0159 0.008
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0081 0.0286 0.0656
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0086 0.0139
Trypanosoma brucei trypanothione reductase 0.0608 0.2953 0.8231
Trypanosoma brucei polo-like protein kinase 0.0282 0.1302 0.3555
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0045 0.0103 0.0023
Schistosoma mansoni lipoxygenase 0.0085 0.0306 0.0306
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0045 0.0103 0.0112
Plasmodium falciparum JmjC domain-containing protein, putative 0.0058 0.0171 0.0329
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0036 0.006 0.0015
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0136 0.0136
Brugia malayi Bromodomain containing protein 0.0062 0.0191 0.0161
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0125 0.0509 0.1311
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0043 0.0094 0.0175
Brugia malayi PXA domain containing protein 0.0064 0.02 0.017
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0341 0.1603 0.2596
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0056 0.0159 0.0128
Echinococcus granulosus jumonji domain containing 1A 0.0058 0.0171 0.0277
Loa Loa (eye worm) hypothetical protein 0.0237 0.1077 0.1074
Echinococcus multilocularis phd:f box containing protein 0.0058 0.0171 0.0204
Brugia malayi Kelch motif family protein 0.0063 0.0196 0.0166
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0332 0.1556 0.4275
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0211 0.0943 0.2569
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.1387 0.6894 0.8969
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0058 0.0171 0.0393
Echinococcus multilocularis 6 phosphofructokinase 0.0221 0.0995 0.119
Echinococcus granulosus SAM and MBT domain containing protein 0.0301 0.1401 0.2268
Loa Loa (eye worm) PXA domain-containing protein 0.0064 0.02 0.0198
Trichomonas vaginalis apoptosis inducing factor, putative 0.0056 0.0159 0.0128
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0062 0.0191 0.0229
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.1268 0.124
Echinococcus granulosus thioredoxin glutathione reductase 0.0611 0.2967 0.4805
Plasmodium vivax SUMO-conjugating enzyme UBC9, putative 0.01 0.0383 0.1032
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.006 0.008
Schistosoma mansoni chromobox protein 0.0036 0.006 0.006
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0403 0.1915 0.1913
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0332 0.1556 0.4275
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0152 0.0647 0.0572
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0065 0.0204 0.0446
Onchocerca volvulus 0.0485 0.2331 0.3658
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0221 0.0995 0.2587
Loa Loa (eye worm) programmed cell death 8 0.0056 0.0159 0.0157
Schistosoma mansoni acetyl-CoA synthetase 0.0045 0.0103 0.0103
Brugia malayi hypothetical protein 0.0036 0.006 0.003
Plasmodium falciparum phosphatidylinositol-4-phosphate 5-kinase 0.0097 0.0368 0.0888
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0056 0.0159 0.008
Mycobacterium tuberculosis Putative ferredoxin reductase 0.1387 0.6894 0.8978
Leishmania major phosphoglycerate kinase C, glycosomal 0.0732 0.3578 1
Brugia malayi beta-lactamase 0.004 0.008 0.005
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0075 0.0257 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0322 0.0291
Echinococcus granulosus histone lysine methyltransferase setb 0.0181 0.0791 0.1281
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0269 0.1235 0.3366
Entamoeba histolytica phosphoglycerate kinase, putative 0.0732 0.3578 1
Echinococcus granulosus chromobox protein 1 0.0222 0.0999 0.1618
Loa Loa (eye worm) hypothetical protein 0.004 0.008 0.0078
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0314 0.1465 0.4043
Echinococcus multilocularis expressed protein 0.1245 0.6175 0.7382
Toxoplasma gondii hypothetical protein 0.0259 0.1189 0.3236
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0056 0.0159 0.032
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0097 0.0368 0.0368
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0211 0.0943 0.0869
Entamoeba histolytica hypothetical protein 0.0064 0.02 0.0474
Brugia malayi Melibiase family protein 0.0079 0.0278 0.0248
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0081 0.0286 0.0351
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0116 0.0114
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.008 0.0082
Loa Loa (eye worm) hypothetical protein 0.0118 0.0474 0.0472
Echinococcus multilocularis Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0097 0.0368 0.044
Loa Loa (eye worm) hypothetical protein 0.0485 0.2331 0.2329
Schistosoma mansoni hypothetical protein 0.0909 0.4475 0.4475
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0877 0.0877
Brugia malayi hypothetical protein 0.0054 0.0152 0.0122
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.006 0.006
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0045 0.0103 0.0112
Loa Loa (eye worm) hypothetical protein 0.0064 0.02 0.0198
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0221 0.0994 0.2747
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.008 0.008
Brugia malayi hypothetical protein 0.0142 0.0597 0.0568
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0065 0.0207 0.0248
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0039 0.0071 0.0071
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0096 0.0065
Brugia malayi Protein cec-1. 0.0036 0.006 0.003
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0598 0.2901 0.3713
Echinococcus multilocularis lysine specific demethylase 6a 0.0058 0.0171 0.0204
Schistosoma mansoni myelin transcription factor 1 myt1 0.0343 0.1612 0.1612
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.1578 0.1552
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0091 0.0212
Giardia lamblia NADH oxidase lateral transfer candidate 0.0211 0.0943 0.2569
Brugia malayi Integrin beta pat-3 precursor 0.0378 0.179 0.1765
Trypanosoma brucei DNA polymerase IV, putative 0.0515 0.2483 0.6899
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0513 0.2473 0.4004
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.121 0.5999 0.5999
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.1387 0.6894 0.8978
Plasmodium falciparum glutathione reductase 0.0211 0.0943 0.2519
Onchocerca volvulus 0.121 0.5999 0.9488
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0081 0.0286 0.0415
Echinococcus granulosus histone acetyltransferase KAT2B 0.0721 0.3525 0.5708
Loa Loa (eye worm) X11 protein 0.0216 0.0969 0.0967
Trypanosoma brucei DNA polymerase kappa, putative 0.0306 0.1423 0.3899
Entamoeba histolytica phosphofructokinase, putative 0.0221 0.0995 0.2717
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0154 0.0654 0.1699
Schistosoma mansoni cpg binding protein 0.0134 0.0555 0.0555
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0056 0.0159 0.032
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0124 0.0503 0.0503
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0065 0.0207 0.0432
Schistosoma mansoni regulator of G protein signaling 0.0064 0.02 0.02
Echinococcus multilocularis axis inhibition protein axin 0.0064 0.02 0.0239
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0056 0.0159 0.0186
Plasmodium vivax 6-phosphofructokinase, putative 0.006 0.0179 0.0458
Loa Loa (eye worm) 6-phosphofructokinase 0.0221 0.0995 0.0993
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0103 0.0023
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0269 0.1235 0.3394
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.008 0.0082
Loa Loa (eye worm) hypothetical protein 0.0114 0.0452 0.045
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0061 0.0183 0.0426
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0045 0.0103 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.0515 0.2483 0.6899
Toxoplasma gondii hypothetical protein 0.011 0.0433 0.1094
Schistosoma mansoni integrin beta subunit 0.0223 0.1003 0.1003
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0474 0.2276 0.3685
Echinococcus multilocularis polycomb protein SCMH1 0.0301 0.1401 0.1675
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0218 0.0977 0.1181
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0045 0.0103 0.01
Trypanosoma cruzi DNA damage repair protein, putative 0.0125 0.0509 0.1347
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0152 0.0647 0.0746
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0103 0.0023
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.01 0.0383 0.0991
Entamoeba histolytica hypothetical protein 0.0341 0.1603 0.4431
Loa Loa (eye worm) glutathione reductase 0.0608 0.2953 0.2951
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0058 0.0171 0.0353
Onchocerca volvulus 0.1274 0.632 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0075 0.0257 0.0636
Schistosoma mansoni integrin alpha 0.0185 0.0811 0.0811
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0056 0.0159 0.0258
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0045 0.0103 0.0023
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0084 0.0303 0.0703
Echinococcus granulosus peptidase Clp S14 family 0.0218 0.0977 0.1583
Schistosoma mansoni cpg binding protein 0.0138 0.0576 0.0576
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0152 0.0299
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0097 0.0368 0.0948
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0084 0.0303 0.0273
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0056 0.0159 0.032
Brugia malayi ube2i2 protein 0.01 0.0383 0.0354
Brugia malayi Pip kinase protein 2 0.121 0.5999 0.5986
Mycobacterium ulcerans hypothetical protein 0.0056 0.0159 0.008
Schistosoma mansoni chromodomain helicase DNA binding protein 0.004 0.008 0.008
Loa Loa (eye worm) jmjC domain-containing protein 0.0256 0.1171 0.1169
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0084 0.0303 0.049
Entamoeba histolytica acyl-CoA synthetase, putative 0.0152 0.0647 0.1736
Giardia lamblia PHD finger protein 15 0.0124 0.0503 0.133
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0211 0.0943 0.0869
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0332 0.1556 0.4324
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0322 0.0291
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0159 0.036
Echinococcus multilocularis Chromobox protein 3 0.0036 0.006 0.0072
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0077 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.006 0.0029
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.006 0.006
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0332 0.1556 0.4197
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0062 0.0191 0.031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0096 0.0065
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0221 0.0995 0.2687
Leishmania major ubiquitin-activating enzyme-like protein 0.0065 0.0204 0.0446
Echinococcus granulosus phosphoglycerate kinase 1 0.0732 0.3578 0.5793
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0211 0.0943 0.2569
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.1578 0.1552
Schistosoma mansoni hypothetical protein 0.0102 0.0394 0.0394
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0056 0.0159 0.0104
Onchocerca volvulus 0.0033 0.0042 0.0019
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0056 0.0159 0.0157
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.008 0.0137
Toxoplasma gondii HEAT repeat-containing protein 0.0085 0.0307 0.0738
Loa Loa (eye worm) hypothetical protein 0.0513 0.2473 0.2471
Echinococcus granulosus zinc finger protein 0.0043 0.0091 0.0148
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.008 0.0137
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0097 0.0368 0.0948
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0095 0.0359 0.0429
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0056 0.0159 0.036
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0056 0.0159 0.0258
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0064 0.02 0.0198
Echinococcus multilocularis regulator of G protein signaling 7 0.0064 0.02 0.0239
Trypanosoma cruzi DNA polymerase eta, putative 0.0392 0.1857 0.5149
Onchocerca volvulus 0.0188 0.0826 0.1264
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0425 0.2024 0.5601
Leishmania major importin beta-1 subunit, putative 0.0069 0.0226 0.0508
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0343 0.1612 0.1586
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0056 0.0159 0.0258
Trichomonas vaginalis phosphofructokinase, putative 0.0221 0.0995 0.0967
Loa Loa (eye worm) hypothetical protein 0.0065 0.0207 0.0205
Loa Loa (eye worm) hypothetical protein 0.0152 0.0647 0.0645
Plasmodium falciparum phosphoglycerate kinase 0.0732 0.3578 1
Schistosoma mansoni ap endonuclease 0.0081 0.0286 0.0286
Echinococcus granulosus DNA methyltransferase 2, putative 0.0061 0.0183 0.0296
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0053 0.0143 0.0251
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0053 0.0143 0.0143
Brugia malayi Bromodomain containing protein 0.0145 0.0609 0.058
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.008 0.0049
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0221 0.0995 0.1204
Schistosoma mansoni axis inhibition protein axin 0.0064 0.02 0.02
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0097 0.0368 0.091
Brugia malayi glutamate synthase 0.0056 0.0159 0.0129
Plasmodium falciparum ferrodoxin reductase-like protein 0.0056 0.0159 0.0296
Schistosoma mansoni DNA helicase recq5 0.0084 0.0303 0.0303
Trichomonas vaginalis rotamase, putative 0.0034 0.0051 0.0019
Leishmania major phosphopantetheinyl transferase-like protein 0.0053 0.0143 0.0275
Loa Loa (eye worm) hypothetical protein 0.0114 0.0452 0.045
Loa Loa (eye worm) pigment dispersing factor receptor c 0.015 0.0633 0.0631
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0506 0.0476
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0045 0.0103 0.0023
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0155 0.066 0.0631
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0061 0.0183 0.0386
Loa Loa (eye worm) hypothetical protein 0.0464 0.2225 0.2223
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0096 0.0065
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0179 0.0147
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0103 0.0072
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.008 0.0082
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0513 0.2473 0.2473
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0513 0.2473 0.4004
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0056 0.0159 0.008
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0045 0.0103 0.0135
Schistosoma mansoni hypothetical protein 0.0448 0.2143 0.2143
Giardia lamblia Phosphoglycerate kinase 0.0732 0.3578 1
Plasmodium vivax hypothetical protein, conserved 0.0036 0.006 0.0125
Brugia malayi PHD-finger family protein 0.0124 0.0503 0.0474
Schistosoma mansoni terminal deoxycytidyl transferase 0.0403 0.1915 0.1915
Loa Loa (eye worm) hypothetical protein 0.004 0.008 0.0078
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0097 0.0368 0.091
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0425 0.2024 0.5619
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.006 0.0179 0.0414
Schistosoma mansoni regulator of G protein signaling 0.0072 0.0243 0.0243
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0056 0.0159 0.032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0043 0.0096 0.0065
Echinococcus multilocularis MAM 0.0033 0.0042 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0205 0.0205
Plasmodium vivax thioredoxin reductase, putative 0.0608 0.2953 0.8247
Loa Loa (eye worm) hypothetical protein 0.0064 0.02 0.0198
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0097 0.0368 0.091
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0193 0.0854 0.0826
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0064 0.02 0.0324
Trichomonas vaginalis Heterochromatin protein, putative 0.0036 0.006 0.0029
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0211 0.0943 0.1526
Toxoplasma gondii propionate-CoA ligase 0.0045 0.0103 0.016
Trichomonas vaginalis chromobox protein, putative 0.0036 0.006 0.0029
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0909 0.4475 0.4473
Mycobacterium ulcerans DNA polymerase IV 0.0515 0.2483 0.2422
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0198 0.0877 0.1049
Brugia malayi M-phase phosphoprotein, mpp8 0.0036 0.006 0.003
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0515 0.2483 0.2459
Loa Loa (eye worm) ube2i2 protein 0.01 0.0383 0.0381
Plasmodium falciparum heterochromatin protein 1 0.0036 0.006 0.0015
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0017 0.0027
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0153 0.065 0.1709
Leishmania major hypothetical protein, conserved 0.0056 0.0159 0.032
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0097 0.0368 0.091
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.0143 0.0275
Echinococcus multilocularis voltage dependent calcium channel 0.0513 0.2473 0.2956
Trypanosoma brucei hypothetical protein, conserved 0.004 0.008 0.0096
Loa Loa (eye worm) hypothetical protein 0.004 0.008 0.0078
Brugia malayi regulator of G-protein signaling rgs-7 0.0064 0.02 0.017
Trichomonas vaginalis dullard protein, putative 0.0065 0.0207 0.0176
Echinococcus granulosus Chromobox protein 3 0.0036 0.006 0.0097
Giardia lamblia Histone acetyltransferase GCN5 0.02 0.0888 0.2416
Leishmania major small ubiquitin protein, putative 0.0035 0.0055 0.0024
Brugia malayi polk-prov protein 0.0237 0.1077 0.1049
Onchocerca volvulus Huntingtin homolog 0.0142 0.0597 0.09
Echinococcus granulosus lysine specific demethylase 5A 0.0222 0.1001 0.1622
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0056 0.0159 0.0128
Brugia malayi PXA domain containing protein 0.0064 0.02 0.017
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0301 0.1401 0.2178
Loa Loa (eye worm) voltage-dependent calcium channel 0.0111 0.0439 0.0437
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0425 0.2024 0.5619
Leishmania major hypothetical protein, conserved 0.004 0.008 0.0096
Schistosoma mansoni regulator of G protein signaling 0.0064 0.02 0.02
Loa Loa (eye worm) helicase 0.0036 0.006 0.0058
Trypanosoma cruzi small ubiquitin protein, putative 0.0035 0.0055 0.0066
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0732 0.3578 0.4603
Trichomonas vaginalis rotamase, putative 0.0034 0.0046 0.0015
Plasmodium vivax hypothetical protein, conserved 0.0097 0.0368 0.0989
Schistosoma mansoni hypothetical protein 0.0065 0.0203 0.0203
Onchocerca volvulus 0.004 0.008 0.0079
Entamoeba histolytica acyl-coA synthetase, putative 0.0152 0.0647 0.1736
Entamoeba histolytica recQ family helicase, putative 0.0102 0.0394 0.1022
Trichomonas vaginalis glutamate synthase, putative 0.0056 0.0159 0.0128
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0046 0.0041
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0056 0.0159 0.0128
Echinococcus multilocularis Regulator of G protein signaling 20 0.0064 0.02 0.0239
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0108 0.0421 0.0527
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0097 0.0368 0.0337
Onchocerca volvulus 0.0033 0.0042 0.0019
Loa Loa (eye worm) hypothetical protein 0.0155 0.0662 0.0659
Entamoeba histolytica hypothetical protein 0.0341 0.1603 0.4431
Mycobacterium ulcerans glutamate synthase subunit beta 0.0056 0.0159 0.008
Leishmania major modification methylase-like protein 0.0061 0.0183 0.0386
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0065 0.0204 0.0486
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0098 0.0374 0.0606
Echinococcus multilocularis tumor protein p63 0.0351 0.1652 0.1975
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0081 0.0286 0.0717
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0075 0.0257 0.0308
Loa Loa (eye worm) integrin alpha pat-2 0.0285 0.1317 0.1315
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.1578 0.1552
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.006 0.0029
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0211 0.0943 0.0943
Loa Loa (eye worm) hypothetical protein 0.0081 0.0288 0.0286
Echinococcus multilocularis chromobox protein 1 0.0222 0.0999 0.1194
Trypanosoma brucei phosphoglycerate kinase 0.0732 0.3578 1
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.02 0.0169
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0041 0.0081 0.0099
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0045 0.0103 0.016
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0513 0.2473 0.2956
Brugia malayi jmjC domain containing protein 0.0474 0.2276 0.2252
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0839 0.0809
Brugia malayi hypothetical protein 0.0064 0.02 0.017
Schistosoma mansoni cpg binding protein 0.0138 0.0576 0.0576
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0051 0.0048
Trypanosoma brucei DNA damage repair protein, putative 0.0125 0.0509 0.1311
Brugia malayi Calcitonin receptor-like protein seb-1 0.015 0.0633 0.0604
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0257 0.0226
Brugia malayi exodeoxyribonuclease III family protein 0.0081 0.0286 0.0256
Trypanosoma brucei hypothetical protein, conserved 0.0125 0.0509 0.1311
Trichomonas vaginalis ap endonuclease, putative 0.0081 0.0286 0.0255
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0056 0.0159 0.0046
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0056 0.0159 0.0128
Brugia malayi F/Y-rich N-terminus family protein 0.0058 0.0171 0.0141
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0116 0.0139
Leishmania major 4-coumarate:coa ligase-like protein 0.0152 0.0647 0.1702
Schistosoma mansoni hypothetical protein 0.0047 0.0116 0.0116
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0056 0.0159 0.036
Entamoeba histolytica hypothetical protein 0.0064 0.02 0.0474
Plasmodium vivax ferrodoxin reductase, putative 0.0056 0.0159 0.0404
Chlamydia trachomatis phosphoglycerate kinase 0.0732 0.3578 1
Brugia malayi Heterochromatin protein 1 0.0222 0.0999 0.0972
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0152 0.0339
Echinococcus multilocularis snurportin 1 0.0909 0.4475 0.5349
Brugia malayi 6-phosphofructokinase 0.0221 0.0995 0.0968
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0114 0.0455 0.1037
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0045 0.0103 0.0023
Echinococcus granulosus voltage dependent calcium channel 0.0111 0.0439 0.0712
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0218 0.0977 0.1253
Trichomonas vaginalis chromobox protein, putative 0.0222 0.0999 0.0971
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0097 0.0368 0.091
Loa Loa (eye worm) hypothetical protein 0.0507 0.244 0.2439
Mycobacterium ulcerans NADH dehydrogenase 0.0056 0.0159 0.008
Echinococcus multilocularis integrin beta 2 0.028 0.1294 0.1547
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0035 0.0055 0.0055
Schistosoma mansoni ap endonuclease 0.0081 0.0286 0.0286
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0045 0.0103 0.0072
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0065 0.0207 0.0539
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0065 0.0204 0.0244
Loa Loa (eye worm) hypothetical protein 0.0142 0.0597 0.0594
Echinococcus multilocularis peregrin 0.0145 0.0609 0.0728
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0075 0.0257 0.0257
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0056 0.0159 0.0129
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0056 0.0159 0.0128
Trypanosoma brucei importin beta-1 subunit, putative 0.0085 0.0307 0.0738
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0045 0.0103 0.0112
Mycobacterium tuberculosis Probable hydrolase 0.004 0.008 0.0082
Trypanosoma cruzi DNA damage repair protein, putative 0.0125 0.0509 0.1347
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0211 0.0943 0.2569
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.004 0.008 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.006 0.0029
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0053 0.0143 0.0275
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0056 0.0159 0.0186
Loa Loa (eye worm) hypothetical protein 0.0114 0.0452 0.045
Echinococcus multilocularis dnaJ subfamily B 0.0448 0.2143 0.2562
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.0058
Loa Loa (eye worm) integrin beta-2 0.0378 0.179 0.1788
Echinococcus granulosus CTD small phosphatase protein like 0.0065 0.0207 0.0336
Leishmania major NADH dehydrogenase, putative 0.0056 0.0159 0.032
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0056 0.0159 0.032
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0081 0.0286 0.0679
Leishmania major trypanothione reductase 0.0608 0.2953 0.8231
Toxoplasma gondii ABC1 family protein 0.004 0.008 0.0096
Loa Loa (eye worm) hypothetical protein 0.0114 0.0452 0.045
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0045 0.0103 0.0023
Loa Loa (eye worm) hypothetical protein 0.0064 0.02 0.0198
Loa Loa (eye worm) hypothetical protein 0.0054 0.0152 0.015
Trypanosoma brucei DNA polymerase eta, putative 0.0669 0.3263 0.911
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0211 0.0943 0.2538
Schistosoma mansoni chromobox protein 0.0036 0.006 0.006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0108 0.0421 0.0527
Giardia lamblia Hypothetical protein 0.0097 0.0368 0.0948
Schistosoma mansoni chromobox protein 0.0222 0.0999 0.0999
Loa Loa (eye worm) hypothetical protein 0.0057 0.0167 0.0165
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0036 0.006 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0789 0.076
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0171 0.0171
Echinococcus multilocularis amyloid beta A4 protein 0.0216 0.0969 0.1159
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0211 0.0943 0.2569
Loa Loa (eye worm) hypothetical protein 0.004 0.0077 0.0075
Loa Loa (eye worm) thioredoxin reductase 0.0608 0.2953 0.2951
Trypanosoma cruzi DNA polymerase eta, putative 0.0669 0.3263 0.9114
Entamoeba histolytica acetyltransferase, GNAT family 0.02 0.0888 0.2416
Plasmodium vivax hypothetical protein, conserved 0.0036 0.006 0.0125
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0269 0.1235 0.3394
Onchocerca volvulus 0.0036 0.006 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.0237 0.1077 0.2917
Loa Loa (eye worm) hypothetical protein 0.0033 0.0042 0.004
Brugia malayi Protein kinase domain containing protein 0.0033 0.0042 0.0012
Loa Loa (eye worm) CXXC zinc finger family protein 0.0134 0.0555 0.0553
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1542 0.7678 1
Echinococcus granulosus Small ubiquitin modifier 2 0.0035 0.0055 0.0089
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0045 0.0103 0.02
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0056 0.0159 0.036
Schistosoma mansoni DNA polymerase IV / kappa 0.0125 0.0509 0.0509
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1678 0.8365 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.0218 0.0977 0.1168
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0056 0.0159 0.032
Toxoplasma gondii DNA methyltransferase 2, putative 0.0061 0.0183 0.0386
Schistosoma mansoni disulfide oxidoreductase 0.0056 0.0159 0.0159
Brugia malayi polybromodomain protein 0.0035 0.0051 0.0021
Brugia malayi A-kinase anchor protein 10, precursor 0.0064 0.02 0.017
Brugia malayi Thioredoxin reductase 0.0608 0.2953 0.2931
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0336 0.1578 0.4362
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0056 0.0159 0.0296
Loa Loa (eye worm) glutaminase 0.2001 1 1
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0116 0.0086
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.006 0.0179 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.0237 0.1077 0.2917
Toxoplasma gondii exonuclease III APE 0.0081 0.0286 0.0679
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0056 0.0159 0.0046
Echinococcus multilocularis voltage dependent calcium channel 0.0513 0.2473 0.2956
Entamoeba histolytica hypothetical protein 0.0036 0.006 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0205 0.0205
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0198 0.0877 0.0875

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 49 nM In vitro inhibition of platelet aggregation in human platelet-rich plasma induced by ADP ChEMBL. No reference
IC50 (functional) = 49 nM In vitro inhibition of platelet aggregation in human platelet-rich plasma induced by ADP ChEMBL. No reference
Ki (binding) = 1.3 nM In vitro binding affinity against human alpha IIb beta3 integrin ChEMBL. No reference
Ki (binding) = 1.3 nM In vitro binding affinity against human alpha IIb beta3 integrin ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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