Detailed information for compound 1394017

Basic information

Technical information
  • TDR Targets ID: 1394017
  • Name: MLS000834773
  • MW: 293.363 | Formula: C18H19N3O
  • H donors: 1 H acceptors: 2 LogP: 2.66 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CCCN(C(=O)Nc1ccc(cc1)C)Cc1ccccc1
  • InChi: 1S/C18H19N3O/c1-15-8-10-17(11-9-15)20-18(22)21(13-5-12-19)14-16-6-3-2-4-7-16/h2-4,6-11H,5,13-14H2,1H3,(H,20,22)
  • InChiKey: ZENHEBYYCOUDNX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-benzyl-N-(2-cyanoethyl)-N'-(4-methylphenyl)urea
  • SMR000458391
  • ZINC04325148

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ataxin 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus pyruvate kinase 0.0034 0.0056 0.0061
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0026 0.0028 0.0604
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0219 0.0675 0.0726
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Brugia malayi hypothetical protein 0.0161 0.0479 0.0479
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0053 0.0057
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0007 0.0152
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.02 0.07
Trypanosoma brucei metacaspase MCA3 0.0019 0.0007 0.0008
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0013 0.0014
Echinococcus granulosus 7tm_1 domain containing protein 0.0429 0.1375 0.1478
Schistosoma mansoni myelin transcription factor 1 myt1 0.0059 0.0139 0.015
Echinococcus granulosus neuropeptide receptor 0.0429 0.1375 0.1478
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0051 0.0112 0.0128
Schistosoma mansoni opsin-like receptor 0.0429 0.1375 0.1478
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0122 0.0349 0.0375
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.01 0.0277 0.0479
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0224 0.0241
Echinococcus granulosus single minded 2 0.0042 0.0084 0.009
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0033 0.0052 0.006
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.0028 0.0625
Onchocerca volvulus 0.0077 0.02 0.0827
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.006 0.0192
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0429 0.1375 0.1478
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.02 0.07
Brugia malayi Cation transporter family protein 0.0018 0.0004 0.0004
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0021 0.0072
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0037 0.0065 0.0113
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0007 0.0152
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0099
Onchocerca volvulus 0.0047 0.0099 0.0404
Trypanosoma cruzi cytochrome P450, putative 0.0086 0.0231 0.0265
Onchocerca volvulus 0.0039 0.0073 0.0292
Brugia malayi CXXC zinc finger family protein 0.0028 0.0036 0.0036
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0176 0.0531 0.2773
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0187 0.0568 0.2734
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0099
Plasmodium vivax JmjC domain containing protein 0.0032 0.0051 0.1131
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.0216 0.0232
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0201 0.4454
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2555 0.8473 0.9108
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0585 0.2101
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0051 0.0112 0.0193
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0028 0.003
Echinococcus granulosus mothers against decapentaplegic 6 0.0022 0.0018 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0021 0.0021
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0092 0.0249 0.0268
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0051 0.0112 0.0401
Brugia malayi MH1 domain containing protein 0.0028 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.014 0.0409 0.0409
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0051 0.0112 0.0193
Giardia lamblia Pyruvate kinase 0.0034 0.0056 0.0234
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Schistosoma mansoni opsin-like receptor 0.0429 0.1375 0.1478
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0095 0.0321
Treponema pallidum NADH oxidase 0.0026 0.0028 0.0145
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0201 0.1066
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.0099 0.0099
Onchocerca volvulus 0.0028 0.0036 0.0138
Plasmodium falciparum amino acid transporter, putative 0.0047 0.0099 0.22
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0021 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0553 0.1982
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Brugia malayi hypothetical protein 0.0024 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0157 0.0468 0.0468
Brugia malayi hypothetical protein 0.003 0.0044 0.0044
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0095 0.0109
Echinococcus granulosus lysine specific demethylase 5A 0.0123 0.0354 0.0381
Mycobacterium ulcerans lipase LipD 0.0077 0.02 0.072
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0013 0.0021
Treponema pallidum fructose-bisphosphate aldolase 0.0581 0.1881 1
Echinococcus multilocularis G protein coupled receptor 139 0.0429 0.1375 0.1478
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0127 0.0136
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0429 0.1375 0.1478
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.0004 0.0004
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.0099 0.0107
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.0251 0.027
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.1274 0.137
Echinococcus multilocularis acetylcholinesterase 0.014 0.0409 0.044
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0015 0.0016
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0086 0.0231 0.0833
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0004 0.0004
Schistosoma mansoni neuropeptide receptor 0.0429 0.1375 0.1478
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0073 0.0078
Echinococcus multilocularis smad 0.005 0.0111 0.0119
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0358
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1881 0.6806
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0127 0.0145
Brugia malayi Serotonin receptor 0.0873 0.2859 0.2859
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0429 0.1375 0.1375
Leishmania major cytochrome p450-like protein 0.0051 0.0112 0.0128
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0051 0.1131
Brugia malayi Pyruvate kinase, M2 isozyme 0.0066 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Brugia malayi MAP kinase sur-1 0.0055 0.0127 0.0127
Echinococcus granulosus g protein coupled receptor 0.0429 0.1375 0.1478
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0109 0.0306 0.0329
Echinococcus multilocularis allatostatin A receptor 0.0429 0.1375 0.1478
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0039 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0047 0.0099 0.0099
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0164 0.0188
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0007 0.0152
Echinococcus granulosus lamin dm0 0.0113 0.032 0.0344
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0019 0.0007 0.003
Echinococcus granulosus NADH dehydrogenase ubiquinone flavoprotein 1 0.0078 0.0203 0.0219
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0418 0.0449
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0022 0.0037
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0131 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0872 0.3142
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0429 0.1375 0.1375
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0142 0.0418 0.0418
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0053 0.0053
Onchocerca volvulus 0.0039 0.0073 0.0291
Echinococcus multilocularis neuropeptides capa receptor 0.0429 0.1375 0.1478
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0051 0.0059
Brugia malayi cytochrome P450 0.0051 0.0112 0.0112
Brugia malayi hypothetical protein 0.0074 0.0191 0.0191
Echinococcus multilocularis sodium and chloride dependent glycine 0.0047 0.0099 0.0107
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0177 0.0535 0.0575
Echinococcus granulosus sodium and chloride dependent glycine 0.0047 0.0099 0.0107
Echinococcus granulosus sodium and chloride dependent glycine 0.0047 0.0099 0.0107
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0051 0.0112 0.0401
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0051 0.0112 0.0193
Loa Loa (eye worm) hypothetical protein 0.003 0.0044 0.0044
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0028 0.003
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0021 0.0043
Echinococcus multilocularis lysine specific demethylase 5A 0.0122 0.0349 0.0375
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0284 0.089 0.154
Echinococcus granulosus pyruvate kinase 0.0034 0.0056 0.0061
Loa Loa (eye worm) neuropeptide F receptor 0.0429 0.1375 0.1375
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Onchocerca volvulus 0.0429 0.1375 0.5788
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0429 0.1375 0.1375
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0097 0.0104
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.047 0.0505
Loa Loa (eye worm) neuropeptide F receptor 0.0429 0.1375 0.1375
Schistosoma mansoni hypothetical protein 0.0429 0.1375 0.1478
Echinococcus granulosus GTP binding nuclear protein Ran 0.0041 0.0081 0.0087
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0224 0.0241
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0021 0.0024
Brugia malayi putative neuropeptide receptor NPR1 0.0429 0.1375 0.1375
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0054 0.0123 0.2713
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Loa Loa (eye worm) glutaminase 2 0.0844 0.276 0.276
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Schistosoma mansoni neuropeptide F-like receptor 0.0429 0.1375 0.1478
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0127 0.0145
Echinococcus granulosus intermediate filament protein 0.0113 0.032 0.0344
Schistosoma mansoni ran 0.0041 0.0081 0.0087
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0053 0.0053
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) hypothetical protein 0.0036 0.0062 0.0062
Echinococcus granulosus small conductance calcium activated potassium 0.0859 0.281 0.3021
Plasmodium falciparum protease, putative 0.0037 0.0065 0.144
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.0115 0.0115
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0247 0.0266
Echinococcus multilocularis neuropeptide receptor 0.0429 0.1375 0.1478
Echinococcus granulosus tm gpcr rhodopsin 0.0429 0.1375 0.1478
Loa Loa (eye worm) NADH-ubiquinone oxidoreductase 51 kDa subunit 0.0078 0.0203 0.0203
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0039 0.0073 0.0084
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0051 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0418 0.0449
Schistosoma mansoni hypothetical protein 0.0074 0.0191 0.0205
Mycobacterium ulcerans hypothetical protein 0.0077 0.02 0.072
Loa Loa (eye worm) hypothetical protein 0.0052 0.0118 0.0118
Entamoeba histolytica Ran family GTPase 0.0041 0.0081 0.0366
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0028 0.0032
Schistosoma mansoni peptidase Clp (S14 family) 0.0152 0.0452 0.0486
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Loa Loa (eye worm) TWK-28 protein 0.0039 0.0073 0.0073
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0142 0.0418 0.0418
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.02 0.0214
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0051 0.0112 0.0193
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0018 0.0004 0.0004
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.006 0.0192
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0075 0.0193 0.0207
Loa Loa (eye worm) MH2 domain-containing protein 0.0022 0.0018 0.0018
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.02 0.07
Loa Loa (eye worm) hypothetical protein 0.0065 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0359 0.1143 0.1143
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0127 0.0136
Onchocerca volvulus 0.0052 0.0115 0.0472
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Loa Loa (eye worm) beta-lactamase 0.0077 0.02 0.02
Schistosoma mansoni Smad4 0.0022 0.0018 0.0019
Brugia malayi hypothetical protein 0.0078 0.0204 0.0204
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.0028 0.0625
Onchocerca volvulus 0.0429 0.1375 0.5788
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0001 0.0002
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0152 0.0452 0.0486
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0872 0.3142
Echinococcus multilocularis g protein coupled receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) norepinephrine transporter 0.0276 0.0865 0.0865
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0018 0.0004 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0086 0.0231 0.0231
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0039 0.0073 0.0073
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0015 0.0016
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0072 0.0182 0.0182
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0437 0.0437
Mycobacterium ulcerans recombinase A 0.0106 0.0297 0.1074
Echinococcus multilocularis neuroligin 0.0024 0.0022 0.0023
Schistosoma mansoni single-minded 0.0048 0.0103 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.1375 0.1478
Brugia malayi jmjC domain containing protein 0.0032 0.0051 0.0051
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0041 0.0081 0.0366
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.02 0.0345
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0051 0.0112 0.0128
Schistosoma mansoni alpha-glucosidase 0.0136 0.0396 0.0426
Loa Loa (eye worm) hypothetical protein 0.0276 0.0865 0.0865
Plasmodium falciparum thioredoxin reductase 0.0026 0.0028 0.0625
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Schistosoma mansoni calcium-activated potassium channel 0.076 0.248 0.2666
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0066 0.0164 0.0284
Schistosoma mansoni loxhd1 0.0039 0.0073 0.0078
Schistosoma mansoni opsin-like receptor 0.0429 0.1375 0.1478
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.006 0.0192
Schistosoma mansoni hypothetical protein 0.033 0.1045 0.1123
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0201 0.101
Echinococcus multilocularis musashi 0.0113 0.032 0.0344
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0018 0.0004 0.0004
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0022 0.0487
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0111 0.0313 0.0313
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0019 0.0007 0.0007
Echinococcus multilocularis fmrfamide receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus multilocularis neuropeptide receptor 0.0429 0.1375 0.1478
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0429 0.1375 0.1478
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0019 0.0007 0.003
Echinococcus granulosus importin subunit beta 1 0.0056 0.0131 0.0141
Echinococcus multilocularis pyruvate kinase 0.0034 0.0056 0.0061
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0157 0.0466 0.0501
Echinococcus multilocularis twik family of potassium channels 0.0039 0.0073 0.0078
Brugia malayi cytoplasmic intermediate filament protein 0.0061 0.0145 0.0145
Echinococcus multilocularis pyruvate kinase 0.0034 0.0056 0.0061
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0429 0.1375 0.1478
Brugia malayi MH2 domain containing protein 0.005 0.0111 0.0111
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0022 0.0023
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus granulosus neuropeptide receptor 0.0429 0.1375 0.1478
Echinococcus granulosus apoptotic protease activating factor 1 0.0078 0.0204 0.0219
Brugia malayi Pre-SET motif family protein 0.064 0.2078 0.2078
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0177 0.0535 0.0535
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.0292 0.0292
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0004 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0123 0.0354 0.0354
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0051 0.0112 0.0193
Mycobacterium tuberculosis Conserved protein 0.0077 0.02 0.0345
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0278 0.0872 0.0872
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0022
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0056 0.0061
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0095 0.0321
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0013 0.0015
Plasmodium vivax potassium channel, putative 0.0039 0.0073 0.1612
Schistosoma mansoni cpg binding protein 0.0028 0.0036 0.0039
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0039 0.0073 0.0078
Brugia malayi Muscleblind-like protein 0.0157 0.0468 0.0468
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0097 0.2137
Brugia malayi Carboxylesterase family protein 0.0024 0.0022 0.0022
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0054 0.0123 0.0141
Schistosoma mansoni nAChR subunit 0.0018 0.0004 0.0004
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0092 0.0249 0.0249
Treponema pallidum recombinase A 0.0106 0.0297 0.1576
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus multilocularis carboxylesterase 5A 0.014 0.0409 0.044
Echinococcus granulosus allatostatin A receptor 0.0429 0.1375 0.1478
Brugia malayi AKH receptor 0.0429 0.1375 0.1375
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0051 0.0055
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0039 0.0073 0.0073
Echinococcus granulosus lamin 0.0113 0.032 0.0344
Trypanosoma brucei CAAX amino terminal protease, putative 0.0177 0.0535 0.0614
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0039 0.0073 0.0073
Echinococcus granulosus peptide allatostatin:somatostatin 0.0429 0.1375 0.1478
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0051 0.0112 0.0193
Brugia malayi Dopamine receptor 0.0429 0.1375 0.1375
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0059 0.0139 0.0139
Schistosoma mansoni sodium/chloride dependent transporter 0.0276 0.0865 0.093
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0018 0.0004 0.0004
Schistosoma mansoni amine GPCR 0.0429 0.1375 0.1478
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0113 0.032 0.0344
Brugia malayi G-protein coupled receptor 0.0429 0.1375 0.1375
Loa Loa (eye worm) TYRA-2 protein 0.0429 0.1375 0.1375
Schistosoma mansoni intermediate filament proteins 0.0113 0.032 0.0344
Schistosoma mansoni TGF-beta signal transducer Smad2 0.005 0.0111 0.0119
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Plasmodium falciparum importin beta, putative 0.0056 0.0131 0.2893
Echinococcus multilocularis NADH dehydrogenase (ubiquinone) flavoprotein 1 0.0078 0.0203 0.0219
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0004 0.0004
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0019 0.0007 0.0021
Echinococcus granulosus RUN 0.0039 0.0073 0.0078
Schistosoma mansoni Smad4 0.005 0.0111 0.0119
Chlamydia trachomatis glutamine binding protein 0.0019 0.0007 0.0125
Echinococcus granulosus neuropeptide Y receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0018 0.0004 0.0004
Brugia malayi Cell death protein 3 precursor 0.0097 0.0268 0.0268
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0051 0.0112 0.0193
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1881 0.6806
Echinococcus granulosus fmrfamide receptor 0.0429 0.1375 0.1478
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0164 0.0188
Trypanosoma brucei calcium-activated potassium channel, putative 0.0039 0.0073 0.0084
Schistosoma mansoni lipoxygenase 0.0109 0.0306 0.0329
Onchocerca volvulus 0.0084 0.0224 0.0932
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Brugia malayi Cytochrome P450 family protein 0.0109 0.0305 0.0305
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0115 0.0124
Onchocerca volvulus 0.0413 0.1323 0.5569
Brugia malayi Serotonin receptor 0.0429 0.1375 0.1375
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0047 0.0099 0.0099
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0201 0.0231
Plasmodium falciparum pyruvate kinase 0.0066 0.0164 0.3629
Echinococcus granulosus alpha 1A adrenergic receptor 0.0429 0.1375 0.1478
Echinococcus multilocularis snurportin 1 0.0601 0.1949 0.2095
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0021 0.0072
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0177 0.0535 0.0575
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0127 0.0145
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Brugia malayi hypothetical protein 0.0039 0.0073 0.0073
Loa Loa (eye worm) carboxylesterase 0.0024 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0072 0.0182 0.0195
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0201 0.0231
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0284 0.089 0.3221
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0092 0.0251 0.027
Schistosoma mansoni hypothetical protein 0.0033 0.0053 0.0057
Trypanosoma cruzi C-8 sterol isomerase, putative 0.263 0.8722 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0081 0.0093
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0127 0.2802
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0092 0.0249 0.132
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0051 0.0112 0.0401
Onchocerca volvulus 0.0092 0.0251 0.1044
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0084 0.038
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0097 0.2137
Onchocerca volvulus 0.0429 0.1375 0.5788
Chlamydia trachomatis recombinase RecA 0.0106 0.0297 0.6571
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0061 0.0066
Echinococcus multilocularis pyruvate kinase 0.0052 0.0117 0.0126
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0032 0.0049 0.0085
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0022 0.0076
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0039 0.0073 0.0073
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0113 0.032 0.0367
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0152 0.0452 0.2155
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0055 0.0125 0.0134
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0113 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0022 0.0038
Mycobacterium ulcerans transmembrane cation transporter 0.0039 0.0073 0.0261
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0168 0.0505 0.2421
Brugia malayi Intermediate filament tail domain containing protein 0.0113 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1881 0.6806
Schistosoma mansoni hypothetical protein 0.0033 0.0053 0.0057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0418 0.0449
Schistosoma mansoni hypothetical protein 0.0033 0.0053 0.0057
Schistosoma mansoni biogenic amine (5HT) receptor 0.1787 0.5909 0.6352
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0061 0.0145 0.0145
Mycobacterium ulcerans hypothetical protein 0.0023 0.0021 0.0072
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.02 0.0345
Schistosoma mansoni glutaminase 0.0844 0.276 0.2967
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus granulosus microtubule associated protein 2 0.2804 0.9303 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0051 0.0112 0.0193
Leishmania major hypothetical protein, conserved 0.0039 0.0073 0.0084
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1881 0.6806
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.064 0.2078 0.2078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0021 0.0036
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0039 0.0073 0.0073
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0019 0.0007 0.0007
Echinococcus multilocularis potassium channel subfamily K 0.0039 0.0073 0.0078
Onchocerca volvulus 0.0429 0.1375 0.5788
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0127 0.0435
Brugia malayi hypothetical protein 0.0328 0.1037 0.1037
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0187 0.0568 0.0983
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0429 0.1375 0.1375
Brugia malayi Probable ClpP-like protease 0.0152 0.0452 0.0452
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.02 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0251 0.027
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0418 0.0449
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0047 0.0099 0.0107
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.006 0.0064
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0115 0.0124
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0022
Brugia malayi intermediate filament protein 0.0113 0.032 0.032
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0051 0.0055
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0047 0.0099 0.0107
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0022 0.0007
Echinococcus multilocularis caspase 2 0.0097 0.0268 0.0288
Echinococcus granulosus carboxylesterase 5A 0.014 0.0409 0.044
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.0028 0.0625
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Echinococcus multilocularis serotonin transporter 0.0276 0.0865 0.093
Schistosoma mansoni cpg binding protein 0.003 0.0042 0.0045
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0028 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0553 0.1982
Schistosoma mansoni acetylcholinesterase 0.0024 0.0022 0.0023
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0075 0.0193 0.0193
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0028 0.0032
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0078 0.0203 0.0233
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0099
Echinococcus granulosus geminin 0.125 0.4115 0.4423
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0491 0.1583 0.274
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0001 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1881 0.6806
Plasmodium vivax hypothetical protein, conserved 0.0077 0.02 0.4414
Toxoplasma gondii CAAX amino terminal protease family protein 0.0037 0.0065 0.144
Schistosoma mansoni amine GPCR 0.0429 0.1375 0.1478
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0553 0.1982
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0018 0.0004 0.0004
Leishmania major DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Giardia lamblia Fructose-bisphosphate aldolase 0.0581 0.1881 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Onchocerca volvulus 0.0077 0.02 0.0827
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0152 0.0452 1
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0051 0.0112 0.0401
Loa Loa (eye worm) hypothetical protein 0.0066 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0109 0.0305 0.0305
Trichomonas vaginalis glutaminase, putative 0.0844 0.276 1
Echinococcus multilocularis microtubule associated protein 2 0.2804 0.9303 1
Schistosoma mansoni alpha-glucosidase 0.0136 0.0396 0.0426
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0224 0.0241
Leishmania major C-8 sterol isomerase-like protein 0.263 0.8722 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0013 0.0014
Echinococcus multilocularis calcium activated potassium channel variant 0.0039 0.0073 0.0078
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0051 0.0112 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Schistosoma mansoni polycystin 1-related 0.0039 0.0073 0.0078
Plasmodium vivax pyruvate kinase, putative 0.0066 0.0164 0.3629
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0018 0.0004 0.0004
Schistosoma mansoni smad 0.0022 0.0018 0.0019
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0097 0.0326
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0039 0.0073 0.0073
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0028 0.0032
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.0028 0.0078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0152 0.0452 1
Echinococcus multilocularis nmda type glutamate receptor 0.0027 0.0032 0.0034
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0429 0.1375 0.1478
Echinococcus granulosus pyruvate kinase 0.0066 0.0164 0.0176
Loa Loa (eye worm) hypothetical protein 0.0033 0.0053 0.0053
Echinococcus multilocularis RUN 0.0039 0.0073 0.0078
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Onchocerca volvulus 0.0085 0.0228 0.0946
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0051 0.0051
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.006 0.0068
Schistosoma mansoni lamin 0.0113 0.032 0.0344
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0201 0.0216
Echinococcus granulosus neuroligin 0.0024 0.0022 0.0023
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0028 0.003
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0127 0.0145
Brugia malayi MH2 domain containing protein 0.0022 0.0018 0.0018
Echinococcus multilocularis dna polymerase eta 0.0021 0.0013 0.0014
Schistosoma mansoni hypothetical protein 0.0601 0.1949 0.2095
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0047 0.0099 0.0107
Loa Loa (eye worm) hypothetical protein 0.0084 0.0224 0.0224
Schistosoma mansoni cytochrome P450 0.0051 0.0112 0.012
Echinococcus multilocularis muscleblind protein 1 0.0157 0.0468 0.0503
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0051 0.0112 0.0401
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0044 0.0051
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0026 0.0028 0.0099
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.003 0.0041 0.0047
Schistosoma mansoni calcium-activated potassium channel 0.0859 0.281 0.3021
Brugia malayi ORL1-like opioid receptor 0.0429 0.1375 0.1375
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0051 0.0112 0.0193
Schistosoma mansoni pyruvate kinase 0.0066 0.0164 0.0176
Loa Loa (eye worm) uncoordinated protein 58 0.0039 0.0073 0.0073
Echinococcus multilocularis serotonin receptor 0.1787 0.5909 0.6352
Echinococcus multilocularis mothers against decapentaplegic 5 0.005 0.0111 0.0119
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0127 0.0145
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0021 0.0072
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0021 0.0024
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.02 0.072
Loa Loa (eye worm) MBCTL1 0.0059 0.0139 0.0139
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.0078 0.0203 0.0219
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0028 0.0145
Toxoplasma gondii hypothetical protein 0.0037 0.0065 0.144
Echinococcus granulosus para nitrobenzyl esterase 0.0024 0.0022 0.0023
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0028 0.0032
Entamoeba histolytica Flap nuclease, putative 0.0054 0.0123 0.0589
Plasmodium vivax importin-beta 2, putative 0.0056 0.0131 0.2893
Leishmania major pyruvate kinase 0.0066 0.0164 0.0188
Loa Loa (eye worm) hypothetical protein 0.0328 0.1037 0.1037
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0429 0.1375 0.1478
Plasmodium falciparum potassium channel 0.0039 0.0073 0.1612
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0053 0.0057
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.0099 0.0107
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus granulosus twik family of potassium channels 0.0039 0.0073 0.0078
Trichomonas vaginalis esterase, putative 0.0077 0.02 0.07
Toxoplasma gondii ion channel protein 0.0039 0.0073 0.1612
Onchocerca volvulus 0.0429 0.1375 0.5788
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0429 0.1375 0.1478
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0024 0.0022 0.0023
Onchocerca volvulus 0.0091 0.0247 0.1029
Schistosoma mansoni nAChR subunit 0.0018 0.0004 0.0004
Echinococcus granulosus 7TM GPCR rhodopsin 0.0429 0.1375 0.1478
Brugia malayi MH1 domain containing protein 0.0028 0.0036 0.0036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.0099 0.0107
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0127 0.0435
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.006 0.0192
Echinococcus granulosus dro:myosuppressin receptor 0.0429 0.1375 0.1478
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.006 0.0064
Brugia malayi sulfakinin receptor protein 0.0429 0.1375 0.1375
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0044 0.0051
Schistosoma mansoni histamine h1 receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.006 0.0143 0.3161
Brugia malayi G protein-coupled receptor F59B2.13 0.0429 0.1375 0.1375
Brugia malayi MH2 domain containing protein 0.0738 0.2407 0.2407
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Onchocerca volvulus 0.0328 0.1037 0.4361
Schistosoma mansoni myosin xvIII 0.0429 0.1375 0.1478
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0022 0.0076
Onchocerca volvulus 0.0429 0.1375 0.5788
Trypanosoma brucei metacaspase MCA2 0.0019 0.0007 0.0008
Brugia malayi follicle stimulating hormone receptor 0.0429 0.1375 0.1375
Treponema pallidum hypothetical protein 0.0037 0.0065 0.0341
Schistosoma mansoni pyruvate kinase 0.0034 0.0056 0.0061
Echinococcus granulosus biogenic amine 5HT receptor 0.1787 0.5909 0.6352
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Mycobacterium leprae putative cytochrome p450 0.0051 0.0112 0.0454
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0152 0.0452 1
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0051 0.0112 0.0193
Mycobacterium tuberculosis Probable reductase 0.0168 0.0505 0.0875
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0047 0.0099 0.0107
Leishmania major cytochrome p450-like protein 0.0051 0.0112 0.0128
Giardia lamblia NADH oxidase lateral transfer candidate 0.0026 0.0028 0.0083
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0015 0.0016
Giardia lamblia DNA repair protein RAD52 0.0389 0.1241 0.6575
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0004 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1881 0.6806
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0581 0.1881 1
Schistosoma mansoni adenoreceptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Toxoplasma gondii cytochrome p450 superfamily protein 0.0051 0.0112 0.2469
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Brugia malayi jmjC domain containing protein 0.0032 0.0051 0.0051
Loa Loa (eye worm) Smad1 0.005 0.0111 0.0111
Schistosoma mansoni twik family of potassium channels-related 0.0039 0.0073 0.0078
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0018 0.0004 0.0004
Echinococcus granulosus tachykinin peptides receptor 99D 0.0429 0.1375 0.1478
Plasmodium vivax SET domain protein, putative 0.0092 0.0251 0.5551
Trypanosoma cruzi ion transport protein, putative 0.0039 0.0073 0.0084
Toxoplasma gondii hypothetical protein 0.0053 0.0118 0.2616
Loa Loa (eye worm) hypothetical protein 0.0028 0.0036 0.0036
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.1787 0.5909 0.5909
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Loa Loa (eye worm) MH1 domain-containing protein 0.005 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0077 0.02 0.02
Plasmodium vivax metacaspase 1, putative 0.0019 0.0007 0.0152
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0039 0.0073 0.0084
Plasmodium vivax protease, putative 0.0037 0.0065 0.144
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0051 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0092 0.0251 0.027
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0019 0.0007 0.0011
Brugia malayi RE15519p 0.0429 0.1375 0.1375
Echinococcus granulosus acetylcholinesterase 0.014 0.0409 0.044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0084 0.038
Entamoeba histolytica hypothetical protein 0.0074 0.0191 0.0955
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Brugia malayi Cytochrome P450 family protein 0.0051 0.0112 0.0112
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.006 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) acetyltransferase 0.0157 0.0466 0.0466
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0028 0.0032
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, putative 0.0078 0.0203 0.0233
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.006 0.006
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.01 0.0276 0.6116
Echinococcus granulosus potassium channel subfamily K 8 0.0039 0.0073 0.0078
Onchocerca volvulus 0.0039 0.0073 0.0292
Echinococcus multilocularis GPCR, family 2 0.0033 0.0053 0.0057
Giardia lamblia Flap structure-specific endonuclease 0.0054 0.0123 0.0589
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0018 0.0004 0.0004
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0201 0.101
Schistosoma mansoni hypothetical protein 0.0859 0.281 0.3021
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0013 0.0043
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0092 0.0249 0.09
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0019 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0041 0.0081 0.0081
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0127 0.0136
Trypanosoma cruzi DNA repair protein, putative 0.0033 0.0052 0.006
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0073 0.0078
Mycobacterium tuberculosis Probable integral membrane protein 0.0037 0.0065 0.0113
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0004 0.0004
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0109 0.0306 0.0329
Loa Loa (eye worm) G-protein coupled receptor 0.0429 0.1375 0.1375
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0429 0.1375 0.1478
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0022 0.0018 0.006
Echinococcus multilocularis twik family of potassium channels 0.0039 0.0073 0.0078
Loa Loa (eye worm) ACC-1 protein 0.0018 0.0004 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0086 0.0231 0.0231
Schistosoma mansoni neuropeptide receptor 0.0429 0.1375 0.1478
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0074 0.0189 0.0328
Schistosoma mansoni jumonji/arid domain-containing protein 0.0123 0.0354 0.0381
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0039 0.0073 0.0084
Echinococcus granulosus dnaJ subfamily B 0.0399 0.1274 0.137
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.0099 0.0107
Schistosoma mansoni twik family of potassium channels-related 0.0039 0.0073 0.0078
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0037 0.0065 0.0113
Echinococcus granulosus dna polymerase eta 0.0021 0.0013 0.0014
Trichomonas vaginalis ran, putative 0.0041 0.0081 0.027
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus multilocularis mothers against decapentaplegic 2 0.0022 0.0018 0.0019
Brugia malayi hypothetical protein 0.0039 0.0073 0.0073
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0113 0.032 0.0344
Schistosoma mansoni hypothetical protein 0.0078 0.0204 0.0219
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.1375 0.1478
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.02 0.02
Brugia malayi Cation transporter family protein 0.0018 0.0004 0.0004
Onchocerca volvulus Glucosylceramidase homolog 0.0183 0.0553 0.2317
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0152 0.0452 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0201 0.0216
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0127 0.0435
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0113 0.032 0.1157
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0065 0.0113
Brugia malayi hypothetical protein 0.0039 0.0073 0.0073
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0022 0.0487
Loa Loa (eye worm) hypothetical protein 0.3012 1 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0059 0.0139 0.015
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0044 0.0983
Brugia malayi acetyltransferase, GNAT family protein 0.0157 0.0466 0.0466
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0276 0.0865 0.0865
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0073 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Schistosoma mansoni amine GPCR 0.0429 0.1375 0.1478
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0109 0.0306 0.1087
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0051 0.0055
Echinococcus granulosus g protein coupled receptor 0.0429 0.1375 0.1478
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0796 0.26 0.2795
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0073 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.0028 0.0625
Brugia malayi neuropeptide F receptor 0.0429 0.1375 0.1375
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1748 0.5777 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.02 0.02
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0095 0.0321
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0051 0.0112 0.0193
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1881 0.6806
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0127 0.0136
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0019 0.0007 0.0125
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0073 0.0078
Brugia malayi G-protein coupled receptor 0.0429 0.1375 0.1375
Trypanosoma cruzi metacaspase, putative 0.0019 0.0007 0.0008
Schistosoma mansoni amine GPCR 0.0785 0.2562 0.2754
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0021 0.0072
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0028 0.0032
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0013 0.0013
Schistosoma mansoni nAChR subunit 0.0018 0.0004 0.0004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.0099 0.22
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0429 0.1375 0.1478
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0106 0.0359
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0553 0.1982
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0051 0.0112 0.0401
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0164 0.0164
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0284 0.089 0.4341
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0201 0.0231
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.1375 0.1478
Echinococcus multilocularis Smad4 0.005 0.0111 0.0119
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0097 0.2137
Onchocerca volvulus NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial homolog 0.0042 0.0083 0.0333
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0004 0.0004
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0051 0.0112 0.0128
Onchocerca volvulus 0.0039 0.0073 0.0292
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0028 0.0032
Leishmania major importin beta-1 subunit, putative 0.0046 0.0095 0.0109
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Echinococcus multilocularis peptidase Clp (S14 family) 0.01 0.0277 0.0297
Onchocerca volvulus Huntingtin homolog 0.0124 0.0358 0.1495
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0131 0.015
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0022 0.0025
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0022 0.0487
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0429 0.1375 0.1478
Schistosoma mansoni sodium/chloride dependent transporter 0.0047 0.0101 0.0109
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.0115 0.0124
Echinococcus multilocularis lamin dm0 0.0113 0.032 0.0344
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0092 0.0249 0.0286
Loa Loa (eye worm) hypothetical protein 0.1787 0.5909 0.5909
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Trypanosoma cruzi ion transport protein, putative 0.0039 0.0073 0.0084
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0127 0.061
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0013 0.0015
Schistosoma mansoni twik family of potassium channels-related 0.0039 0.0073 0.0078
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.0028 0.0032
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0041 0.0081 0.0093
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0152 0.0452 0.2399
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0022 0.0466
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0041 0.0081 0.1795
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.0028 0.0625
Echinococcus multilocularis lamin 0.0113 0.032 0.0344
Brugia malayi beta-lactamase family protein 0.0077 0.02 0.02
Schistosoma mansoni microtubule-associated protein tau 0.2804 0.9303 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0077 0.02 0.02
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0051 0.0055
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0429 0.1375 0.1478
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0004 0.0004
Loa Loa (eye worm) LGC-31 protein 0.0018 0.0004 0.0004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.0099 0.0099
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Onchocerca volvulus 0.0078 0.0204 0.0845
Plasmodium vivax amine transporter, putative 0.0047 0.0099 0.22
Echinococcus multilocularis apoptotic protease activating factor 1 0.0078 0.0204 0.0219
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.047 0.0505
Onchocerca volvulus 0.0039 0.0073 0.0292
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0581 0.1881 0.6806
Schistosoma mansoni ap endonuclease 0.0077 0.0201 0.0216
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.006 0.006
Schistosoma mansoni smad1 5 8 and 0.005 0.0111 0.0119
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Mycobacterium leprae Probable lipase LipE 0.0077 0.02 0.0893
Trypanosoma cruzi cytochrome P450, putative 0.0086 0.0231 0.0265
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0106 0.0359
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0152 0.0452 0.1634
Brugia malayi Dopamine receptor protein 2 0.0429 0.1375 0.1375
Brugia malayi larval opioid receptor 0.0429 0.1375 0.1375
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0018 0.0004 0.0004
Echinococcus granulosus mothers against decapentaplegic 5 0.005 0.0111 0.0119
Entamoeba histolytica CAAX amino terminal protease family 0.0037 0.0065 0.028
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0022 0.0112
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0015
Trypanosoma brucei protein kinase, putative 0.0055 0.0127 0.0145
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.02 0.0345
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0168 0.0505 0.0875
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0161 0.0479 0.0479
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0051 0.0112 0.0401
Echinococcus granulosus pyruvate kinase 0.0034 0.0056 0.0061
Echinococcus multilocularis mothers against decapentaplegic 6 0.0022 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0013
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0044 0.0983
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0051 0.0112 0.0401
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0041 0.0081 0.0081
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Echinococcus granulosus caspase 2 0.0097 0.0268 0.0288
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0092 0.0251 0.5551
Onchocerca volvulus 0.0091 0.0247 0.1029
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0039 0.0073 0.0073
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0164 0.0677
Brugia malayi Cation transporter family protein 0.0018 0.0004 0.0004
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0164 0.0677
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0092 0.0249 0.0268
Brugia malayi Pre-SET motif family protein 0.0092 0.0251 0.0251
Brugia malayi Carboxylesterase family protein 0.0024 0.0022 0.0022
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0044 0.0051
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0099 0.22
Leishmania major pyruvate kinase 0.0066 0.0164 0.0188
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0201 0.0348
Onchocerca volvulus 0.0429 0.1375 0.5788
Brugia malayi Trypsin family protein 0.0091 0.0247 0.0247
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0053 0.0118 0.0624
Leishmania major potassium channel subunit-like protein 0.0039 0.0073 0.0084
Echinococcus granulosus biogenic amine 5HT receptor 0.0796 0.26 0.2795
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0053 0.0118 0.2616
Loa Loa (eye worm) hypothetical protein 0.0401 0.128 0.128
Echinococcus granulosus potassium channel subfamily K 8 0.0039 0.0073 0.0078
Echinococcus multilocularis somatostatin receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) solute carrier family 6 member 4 0.0276 0.0865 0.0865
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Mycobacterium tuberculosis Conserved protein 0.0077 0.02 0.0345
Mycobacterium leprae Conserved hypothetical protein 0.0051 0.0112 0.0454
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0044 0.0983
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Schistosoma mansoni growth hormone secretagogue receptor 0.0429 0.1375 0.1478
Echinococcus multilocularis caspase 8 0.0019 0.0007 0.0007
Echinococcus multilocularis sodium and chloride dependent glycine 0.0047 0.0099 0.0107
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.02 0.0229
Loa Loa (eye worm) cytochrome P450 0.0051 0.0112 0.0112
Leishmania major protein kinase, putative 0.0023 0.0019 0.0022
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.0078 0.0203 0.0714
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0046 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.1344 0.443 0.443
Echinococcus multilocularis potassium channel subfamily K 8 0.0039 0.0073 0.0078
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0039 0.0073 0.0073
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0429 0.1375 0.1478
Echinococcus multilocularis TGF beta signal transducer SmadC 0.005 0.0111 0.0119
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0039 0.0073 0.0078
Echinococcus multilocularis pyruvate kinase 0.0066 0.0164 0.0176
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0053 0.0053
Echinococcus multilocularis g-protein coupled receptor 0.0429 0.1375 0.1478
Plasmodium vivax flap endonuclease 1, putative 0.0054 0.0123 0.2713
Schistosoma mansoni nAChR subunit 0.0018 0.0004 0.0004
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0047 0.0099 0.0107
Trypanosoma cruzi DNA repair protein, putative 0.0033 0.0052 0.006
Onchocerca volvulus Huntingtin homolog 0.0124 0.0358 0.1495
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0051 0.0112 0.0193
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0056 0.1247
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.0004 0.0004
Schistosoma mansoni nAChR subunit 0.0018 0.0004 0.0004
Trypanosoma cruzi metacaspase, putative 0.0019 0.0007 0.0008
Onchocerca volvulus 0.0035 0.0061 0.0243
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0418 0.0449
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.01 0.0276 0.1412
Loa Loa (eye worm) thioredoxin reductase 0.0074 0.0189 0.0189
Onchocerca volvulus 0.0429 0.1375 0.5788
Plasmodium falciparum flap endonuclease 1 0.0054 0.0123 0.2713
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0073 0.0078
Brugia malayi mothers against decapentaplegic homolog 3 0.0022 0.0018 0.0018
Trypanosoma brucei pyruvate kinase 1 0.0066 0.0164 0.0188
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0039 0.0073 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.1375 0.1478
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0004 0.0004
Treponema pallidum sodium- and chloride- dependent transporter 0.0276 0.0865 0.4598
Loa Loa (eye worm) hypothetical protein 0.014 0.0409 0.0409
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0152 0.0452 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0118 0.0118
Mycobacterium ulcerans NADH dehydrogenase I subunit F 0.0078 0.0203 0.0734
Brugia malayi Pyruvate kinase, muscle isozyme 0.0066 0.0164 0.0164
Echinococcus multilocularis g protein coupled receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0099
Onchocerca volvulus 0.0039 0.0073 0.0292
Echinococcus multilocularis nAChR subunit 0.0018 0.0004 0.0004
Echinococcus multilocularis neuropeptide s receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) hypothetical protein 0.0077 0.02 0.02
Schistosoma mansoni gliotactin 0.0024 0.0022 0.0023
Plasmodium falciparum metacaspase 1 0.0019 0.0007 0.0152
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.0028 0.0049
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0051 0.0112 0.0401
Onchocerca volvulus 0.0047 0.0099 0.0404
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Echinococcus granulosus neuropeptides capa receptor 0.0429 0.1375 0.1478
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0047 0.0099 0.0107
Loa Loa (eye worm) transcription factor SMAD2 0.0738 0.2407 0.2407
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.0028 0.0078
Schistosoma mansoni jumonji/arid domain-containing protein 0.0123 0.0354 0.0381
Trichomonas vaginalis spcc417.12 protein, putative 0.0024 0.0022 0.0054
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0039 0.0073 0.0073
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0039 0.0073 0.0126
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0051 0.0112 0.0401
Echinococcus multilocularis caspase 0.0019 0.0007 0.0007
Schistosoma mansoni importin beta-1 0.0056 0.0131 0.0141
Entamoeba histolytica hypothetical protein 0.0046 0.0095 0.0442
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0021 0.0072
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.001 0.001
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0429 0.1375 0.1478
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0039 0.0073 0.0073
Brugia malayi putative neuropeptide receptor 0.0429 0.1375 0.1375
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0022 0.0023
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0051 0.0112 0.0401
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.02 0.07
Loa Loa (eye worm) hypothetical protein 0.0157 0.0468 0.0468
Echinococcus multilocularis acetylcholinesterase 0.014 0.0409 0.044
Echinococcus multilocularis fmrfamide receptor 0.0429 0.1375 0.1478
Onchocerca volvulus 0.0276 0.0865 0.3637
Echinococcus granulosus neuropeptide Y receptor 0.0429 0.1375 0.1478
Schistosoma mansoni sodium/chloride dependent transporter 0.0047 0.0099 0.0107
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0028 0.0032
Schistosoma mansoni jumonji domain containing protein 0.0122 0.0349 0.0375
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0429 0.1375 0.1478
Trypanosoma brucei metacaspase 0.0019 0.0007 0.0008
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0047 0.0099 0.0107
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0152 0.0452 0.0452
Echinococcus granulosus calcium activated potassium channel variant 0.0039 0.0073 0.0078
Brugia malayi Carboxylesterase family protein 0.0024 0.0022 0.0022
Onchocerca volvulus 0.0429 0.1375 0.5788
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.0216 0.0232
Loa Loa (eye worm) hypothetical protein 0.0105 0.0292 0.0292
Brugia malayi Importin beta-1 subunit 0.0056 0.0131 0.0131
Brugia malayi Carboxylesterase family protein 0.0024 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0026 0.0028 0.0099
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.006 0.0192
Echinococcus granulosus snurportin 1 0.0601 0.1949 0.2095
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Brugia malayi Cytochrome P450 family protein 0.0086 0.0231 0.0231
Schistosoma mansoni hypothetical protein 0.0039 0.0073 0.0078
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.0051
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0051 0.0112 0.0401
Onchocerca volvulus 0.0429 0.1375 0.5788
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0051 0.0112 0.0193
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0004 0.0004
Onchocerca volvulus 0.0429 0.1375 0.5788
Loa Loa (eye worm) hypothetical protein 0.0113 0.032 0.032
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Echinococcus multilocularis muscleblind protein 0.0157 0.0468 0.0503
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Toxoplasma gondii pyruvate kinase PyK1 0.0066 0.0164 0.3629
Mycobacterium ulcerans glutaminase 0.0844 0.276 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0429 0.1375 0.1478
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0004 0.0004
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0601 0.1949 0.1949
Echinococcus granulosus muscleblind protein 0.0157 0.0468 0.0503
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0015 0.0016
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0201 0.0706
Echinococcus multilocularis g protein coupled receptor 0.0429 0.1375 0.1478
Plasmodium vivax thioredoxin reductase, putative 0.0074 0.0189 0.419
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0027 0.0032 0.0034
Leishmania major metacaspase, putative 0.0019 0.0007 0.0008
Onchocerca volvulus 0.0039 0.0073 0.0292
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0015 0.0015
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0075 0.0193 0.0193
Entamoeba histolytica hypothetical protein 0.0074 0.0191 0.0955
Schistosoma mansoni sodium-dependent amino acid transporter 0.0047 0.0099 0.0107
Echinococcus multilocularis flap endonuclease 1 0.0054 0.0123 0.0132
Echinococcus granulosus sex peptide receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) acetylcholinesterase 1 0.014 0.0409 0.0409
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.006 0.0192
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0201 0.417
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0144 0.3186
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0276 0.0865 0.093
Schistosoma mansoni hypothetical protein 0.0429 0.1375 0.1478
Schistosoma mansoni hypothetical protein 0.0051 0.0112 0.012
Echinococcus granulosus twik family of potassium channels 0.0039 0.0073 0.0078
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.0004 0.0004
Echinococcus granulosus smad 0.005 0.0111 0.0119
Brugia malayi Melatonin receptor type 1A 0.0429 0.1375 0.1375
Schistosoma mansoni nAChR subunit 0.0018 0.0004 0.0004
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0039 0.0073 0.0073
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0013 0.0014
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0007 0.0152
Schistosoma mansoni flap endonuclease-1 0.0049 0.0105 0.0113
Schistosoma mansoni pyruvate kinase 0.0066 0.0164 0.0176
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0061 0.0218
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0553 0.1982
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.047 0.047
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.047 0.047
Schistosoma mansoni nAChR subunit 0.0018 0.0004 0.0004
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.02 0.0214
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.047 0.0505
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0099
Schistosoma mansoni DNA polymerase eta 0.0021 0.0013 0.0014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0429 0.1375 0.1375
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0047 0.0099 0.2182
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0021 0.0036
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0047 0.0099 0.0107
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0152 0.0452 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0429 0.1375 0.1478
Echinococcus granulosus serotonin transporter 0.0276 0.0865 0.093
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase I subunit F 0.0078 0.0203 0.4221
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 0.0078 0.0203 0.0233
Schistosoma mansoni alpha glucosidase 0.0035 0.006 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Trypanosoma brucei pyruvate kinase 1, putative 0.0066 0.0164 0.0188
Echinococcus granulosus g protein coupled receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0059 0.0139 0.0139
Brugia malayi excitatory GABA receptor EXP-1A 0.0018 0.0004 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Loa Loa (eye worm) nuclear factor I 0.0028 0.0036 0.0036
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0113 0.032 0.0344
Echinococcus multilocularis small conductance calcium activated potassium 0.0859 0.281 0.3021
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0103 0.011
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0039 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0099
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0073 0.0073
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0429 0.1375 0.5788
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0092 0.0249 0.5503
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0201 0.0201
Echinococcus granulosus dna polymerase kappa 0.0021 0.0013 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0051 0.0112 0.0193
Echinococcus multilocularis orexin receptor type 2 0.0429 0.1375 0.1478
Brugia malayi MH1 domain containing protein 0.005 0.0111 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0051 0.0112 0.0193
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0051 0.0112 0.0128
Brugia malayi Flap endonuclease-1 0.0054 0.0123 0.0123
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0039 0.0073 0.0078
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0429 0.1375 0.1375
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0201 0.0706
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.006 0.0192
Brugia malayi hypothetical protein 0.0039 0.0073 0.0073
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0219 0.0675 0.0726
Echinococcus granulosus peptidase Clp S14 family 0.01 0.0277 0.0297
Chlamydia trachomatis hypothetical protein 0.0037 0.0065 0.1421
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0013 0.0022
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.02 0.0345
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.0004 0.0004
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.02 0.0345
Loa Loa (eye worm) hypothetical protein 0.0077 0.02 0.02
Giardia lamblia Pyruvate kinase 0.0066 0.0164 0.081
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0004 0.0004
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.01 0.0276 0.6116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.1375 0.1478
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0039 0.0073 0.0073
Trypanosoma brucei cytochrome P450, putative 0.0086 0.0231 0.0265
Loa Loa (eye worm) hypothetical protein 0.0078 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0015 0.0016
Brugia malayi MH1 domain containing protein 0.005 0.0111 0.0111
Toxoplasma gondii ABC1 family protein 0.0077 0.02 0.4414
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0157 0.0466 0.0501
Echinococcus granulosus G protein coupled receptor 139 0.0429 0.1375 0.1478
Schistosoma mansoni biogenic amine receptor 0.0429 0.1375 0.1478
Echinococcus granulosus histone lysine methyltransferase setb 0.0092 0.0251 0.027
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0047 0.0099 0.0107
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.0051
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.0099 0.22
Mycobacterium ulcerans ion transport protein 0.0039 0.0073 0.0261
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0152 0.0452 0.0486
Entamoeba histolytica CAAX prenyl protease family 0.0177 0.0535 0.2797
Schistosoma mansoni hypothetical protein 0.125 0.4115 0.4423
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0051 0.0112 0.0401
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.0078 0.0203 0.0714
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0084 0.1853
Loa Loa (eye worm) carboxylesterase 0.0024 0.0022 0.0022
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0429 0.1375 0.1478
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0051 0.0055
Echinococcus granulosus neuropeptides capa receptor 0.0429 0.1375 0.1478
Trypanosoma cruzi metacaspase, putative 0.0019 0.0007 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0028 0.0032
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0039 0.0073 0.0322
Loa Loa (eye worm) hypothetical protein 0.0077 0.02 0.02
Plasmodium vivax glutathione reductase, putative 0.0074 0.0189 0.419
Brugia malayi RNA, U transporter 1 0.016 0.0477 0.0477
Schistosoma mansoni rab6-interacting 0.0039 0.0073 0.0078
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0201 0.0726
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0055 0.0125 0.0134
Echinococcus granulosus neuropeptide receptor A26 0.0429 0.1375 0.1478
Echinococcus granulosus acetylcholinesterase 0.014 0.0409 0.044
Schistosoma mansoni hypothetical protein 0.125 0.4115 0.4423
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0039 0.0073 0.0073
Plasmodium falciparum thioredoxin reductase 0.0074 0.0189 0.419
Leishmania major hypothetical protein, conserved 0.0077 0.02 0.0229
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Onchocerca volvulus 0.0024 0.0022 0.0076
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Loa Loa (eye worm) intermediate filament protein 0.0113 0.032 0.032
Onchocerca volvulus 0.0113 0.032 0.1336
Schistosoma mansoni twik family of potassium channels-related 0.0039 0.0073 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0051 0.0112 0.0193
Plasmodium falciparum transporter, putative 0.0047 0.0099 0.22
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0127 0.0145
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0152 0.0452 1
Schistosoma mansoni lipoxygenase 0.0039 0.0073 0.0078
Mycobacterium leprae Probable pyruvate kinase PykA 0.0066 0.0164 0.0716
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0007 0.0008
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0047 0.0099 0.0107
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0092 0.0251 0.0251
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0052 0.0115 0.0115
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0007 0.0008
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0024 0.0022 0.0054
Trypanosoma brucei trypanothione reductase 0.0074 0.0189 0.0217
Leishmania major trypanothione reductase 0.0074 0.0189 0.0217
Loa Loa (eye worm) glutathione reductase 0.0074 0.0189 0.0189
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0429 0.1375 0.1478
Schistosoma mansoni ran 0.0041 0.0081 0.0087
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0092 0.0249 0.0286
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0051 0.0051
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0418 0.0449
Schistosoma mansoni hypothetical protein 0.0429 0.1375 0.1478
Mycobacterium leprae conserved hypothetical protein 0.0077 0.02 0.0893
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0051 0.0112 0.0193
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0051 0.0059
Schistosoma mansoni cpg binding protein 0.003 0.0042 0.0045
Brugia malayi Doublecortin family protein 0.0039 0.0073 0.0073
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0164 0.0571
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0018 0.0004 0.0004
Echinococcus granulosus nmda type glutamate receptor 0.0027 0.0032 0.0034
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0429 0.1375 0.1478
Trypanosoma cruzi trypanothione reductase, putative 0.0074 0.0189 0.0217
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0581 0.1881 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0092 0.0249 0.0268
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.02 0.0229
Echinococcus multilocularis neuropeptide FF receptor 2 0.0429 0.1375 0.1478
Echinococcus granulosus tm gpcr rhodopsin 0.0429 0.1375 0.1478
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0097 0.0326
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0013 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0192 0.0585 0.2101
Echinococcus granulosus thioredoxin glutathione reductase 0.0075 0.0193 0.0207
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0013 0.0022
Echinococcus granulosus histone acetyltransferase KAT2B 0.0152 0.0451 0.0485
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Leishmania major hypothetical protein, conserved 0.0032 0.0051 0.0059
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0004 0.0004
Brugia malayi Thioredoxin reductase 0.0074 0.0189 0.0189
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0051 0.0112 0.0401
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0039 0.0073 0.0073
Plasmodium falciparum glutathione reductase 0.0074 0.0189 0.419
Brugia malayi beta-lactamase 0.0077 0.02 0.02
Echinococcus granulosus GPCR family 2 0.0033 0.0053 0.0057
Plasmodium vivax potassium channel, putative 0.0039 0.0073 0.1612
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0429 0.1375 0.1375
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.006 0.0068
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0044 0.0983
Onchocerca volvulus 0.0023 0.0021 0.0072
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0053 0.0057
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0278 0.0872 0.0872
Brugia malayi jmjC domain containing protein 0.0122 0.0349 0.0349
Schistosoma mansoni smad 0.005 0.0111 0.0119
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0191 0.0205
Entamoeba histolytica CAAX amino terminal protease family 0.0037 0.0065 0.028
Loa Loa (eye worm) melatonin receptor type 1A 0.0429 0.1375 0.1375
Brugia malayi G protein-coupled receptor 0.0429 0.1375 0.1375
Mycobacterium ulcerans integral membrane protein 0.0037 0.0065 0.0233
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0872 0.3142
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0053 0.0118 0.0487
Schistosoma mansoni hypothetical protein 0.0429 0.1375 0.1478
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0109 0.0306 0.1087
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0073 0.024
Echinococcus multilocularis histone acetyltransferase MYST2 0.0059 0.0139 0.015
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.01 0.0276 0.6116
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0039 0.0139
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0013 0.0015
Echinococcus granulosus histone acetyltransferase MYST2 0.0059 0.0139 0.015
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0429 0.1375 0.1478
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0201 0.0201
Schistosoma mansoni caspase-7 (C14 family) 0.0019 0.0007 0.0007
Onchocerca volvulus 0.0047 0.0099 0.0404
Loa Loa (eye worm) glutaminase 0.0844 0.276 0.276
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0429 0.1375 0.1478
Loa Loa (eye worm) TWK-7 protein 0.0039 0.0073 0.0073
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0051 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0015 0.0016
Brugia malayi neuropeptide F receptor 0.0429 0.1375 0.1375
Echinococcus granulosus caspase 8 0.0019 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0051 0.0112 0.0401
Brugia malayi GnHR receptor homolog 0.0429 0.1375 0.1375
Plasmodium falciparum potassium channel 0.0039 0.0073 0.1612
Leishmania major cytochrome p450-like protein 0.0086 0.0231 0.0265
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0091 0.0247 0.0266
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.0292 0.0292
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0113 0.032 0.032
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0127 0.0435
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.006 0.0192
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0056 0.0061
Schistosoma mansoni neuroligin 3 (S09 family) 0.0024 0.0022 0.0023
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0051 0.0112 0.0401
Leishmania major NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0078 0.0203 0.0233
Onchocerca volvulus 0.0024 0.0022 0.0076
Onchocerca volvulus Neuropeptide F receptor homolog 0.0429 0.1375 0.5788
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0039 0.0073 0.0078
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0201 0.0231
Schistosoma mansoni calcium-activated potassium channel 0.0039 0.0073 0.0078
Toxoplasma gondii hypothetical protein 0.0047 0.0099 0.22
Echinococcus granulosus orexin receptor type 2 0.0429 0.1375 0.1478
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0021 0.0043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0937 0.3072 0.3302
Mycobacterium tuberculosis Carboxylesterase LipT 0.0024 0.0022 0.0037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0124 0.0358 0.0358
Echinococcus granulosus potassium channel subfamily K 0.0039 0.0073 0.0078
Onchocerca volvulus 0.0429 0.1375 0.5788
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0018 0.0004 0.0004
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0106 0.0297 0.6403
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0553 0.1982
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0004 0.0004
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0168 0.0505 0.0875
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0418 0.0449
Echinococcus multilocularis importin subunit beta 1 0.0056 0.0131 0.0141
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.02 0.0345
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0872 0.3142
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Echinococcus granulosus TGF beta signal transducer SmadC 0.005 0.0111 0.0119
Mycobacterium ulcerans beta-lactamase 0.0077 0.02 0.072
Brugia malayi Carboxylesterase family protein 0.014 0.0409 0.0409
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0113 0.032 0.1157
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0041 0.0081 0.1795
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0051 0.0112 0.0401
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0039 0.0073 0.0073
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.006 0.0252
Schistosoma mansoni neuropeptide receptor 0.0429 0.1375 0.1478
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0056 0.1247
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0041 0.0081 0.0087
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.006 0.0192
Onchocerca volvulus 0.0024 0.0022 0.0076
Echinococcus granulosus phd:f box containing protein 0.0032 0.0051 0.0055
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Onchocerca volvulus 0.0024 0.0022 0.0076
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Echinococcus multilocularis CAAX prenyl protease 2 0.0177 0.0535 0.0575
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.006 0.0252
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0122 0.0349 0.0375
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0028 0.0032
Brugia malayi mbt repeat family protein 0.0052 0.0115 0.0115
Echinococcus multilocularis pyruvate kinase 0.0034 0.0056 0.0061
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Mycobacterium tuberculosis Conserved protein 0.0077 0.02 0.0345
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0051 0.0112 0.0128
Echinococcus multilocularis potassium channel subfamily K 8 0.0039 0.0073 0.0078
Onchocerca volvulus 0.0113 0.032 0.1336
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0872 0.3142
Trypanosoma brucei Metacaspase-4 0.0019 0.0007 0.0008
Brugia malayi Carboxylesterase family protein 0.014 0.0409 0.0409
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0056 0.0131 0.0131
Leishmania major hypothetical protein, conserved 0.003 0.0044 0.0051
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Echinococcus granulosus CAAX prenyl protease 2 0.0177 0.0535 0.0575
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0059 0.0139 0.015
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0127 0.0145
Echinococcus granulosus mothers against decapentaplegic 2 0.0022 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0859 0.281 0.281
Echinococcus multilocularis dro:myosuppressin receptor 0.0429 0.1375 0.1478
Schistosoma mansoni calcium-activated potassium channel 0.0039 0.0073 0.0078
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.0292 0.0292
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0429 0.1375 0.1478
Brugia malayi beta-lactamase family protein 0.0077 0.02 0.02
Schistosoma mansoni ap endonuclease 0.0077 0.0201 0.0216
Brugia malayi glucose-6-phosphate dehydrogenase 0.0092 0.0249 0.0249
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0021 0.0072
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0051 0.0055
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0429 0.1375 0.1478
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0201 0.4454
Echinococcus multilocularis neuropeptide Y receptor 0.0429 0.1375 0.1478
Brugia malayi hypothetical protein 0.0047 0.0099 0.0099
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0191 0.0205
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0251 0.027
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0106 0.0297 0.1382
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.01 0.0276 0.0979
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0164 0.0164
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0054 0.0123 0.0141
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0013 0.0043
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0018 0.0004 0.0004
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.006 0.1321
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0164 0.0164
Schistosoma mansoni twik family of potassium channels-related 0.0039 0.0073 0.0078
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0022 0.0487
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0429 0.1375 0.1478
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0073 0.1605
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.1375 0.1478
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0429 0.1375 0.1478
Toxoplasma gondii exonuclease III APE 0.0077 0.0201 0.4454
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0251 0.027
Leishmania major GTP-binding protein, putative 0.0041 0.0081 0.0093
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0018 0.0004 0.0004
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0429 0.1375 0.1478
Schistosoma mansoni hypothetical protein 0.0399 0.1274 0.137
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.02 0.0214
Leishmania major calcium/potassium channel (CAKC), putative 0.0039 0.0073 0.0084
Entamoeba histolytica hypothetical protein 0.0074 0.0191 0.0955
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.0051
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0039 0.0073 0.0084
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0026 0.0028 0.0099
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0039 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Leishmania major ion transport protein-like protein 0.0039 0.0073 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0152 0.0164
Onchocerca volvulus 0.0429 0.1375 0.5788
Schistosoma mansoni neuropeptide f receptor 76f 0.0429 0.1375 0.1478
Toxoplasma gondii hypothetical protein 0.0047 0.0099 0.22
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0429 0.1375 0.1478
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.014 0.0409 0.044
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0051 0.0059
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0075 0.0193 0.0207
Onchocerca volvulus 0.0024 0.0022 0.0076
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0073 0.0078
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.006 0.0143 0.0514
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.006 0.0068
Mycobacterium ulcerans hypothetical protein 0.0037 0.0065 0.0233
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0177 0.0535 0.0614
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0018 0.0004 0.0004
Trypanosoma brucei unspecified product 0.0021 0.0013 0.0015
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0051 0.1131
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Schistosoma mansoni smad1 5 8 and 0.005 0.0111 0.0119
Echinococcus multilocularis geminin 0.125 0.4115 0.4423
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0051 0.0112 0.0193
Loa Loa (eye worm) serotonin transporter b 0.0276 0.0865 0.0865
Echinococcus multilocularis G-protein coupled receptor, putative 0.0429 0.1375 0.1478
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0429 0.1375 0.1375
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0127 0.0136
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0018 0.0004 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0187 0.0568 0.0983
Trypanosoma cruzi metacaspase, putative 0.0019 0.0007 0.0008
Onchocerca volvulus 0.0077 0.02 0.0827
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0177 0.0535 0.0614
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.01 0.0276 0.0979
Echinococcus granulosus serotonin receptor 0.0429 0.1375 0.1478
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0001 0.0022
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0092 0.0249 0.0286
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0081 0.0093
Echinococcus granulosus neuropeptide s receptor 0.0429 0.1375 0.1478
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.01 0.0276 0.0979
Toxoplasma gondii ion channel protein 0.0039 0.0073 0.1612
Schistosoma mansoni rab6-interacting 0.0039 0.0073 0.0078
Schistosoma mansoni twik family of potassium channels-related 0.0039 0.0073 0.0078
Entamoeba histolytica hypothetical protein 0.0024 0.0022 0.005
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0013 0.0013
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0224 0.0224
Brugia malayi hypothetical protein 0.0124 0.0358 0.0358
Schistosoma mansoni Smad4 0.0022 0.0018 0.0019
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0105 0.0295 0.0295
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0429 0.1375 0.1478
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0051 0.0112 0.0401
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.0115 0.0124
Loa Loa (eye worm) hypothetical protein 0.0097 0.0268 0.0268
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0073 0.0078
Toxoplasma gondii HEAT repeat-containing protein 0.0056 0.0131 0.2893
Toxoplasma gondii thioredoxin reductase 0.0074 0.0189 0.419
Brugia malayi PAS domain containing protein 0.0048 0.0103 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Echinococcus multilocularis pyruvate kinase 0.0066 0.0164 0.0176
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0028 0.0032
Echinococcus multilocularis neuropeptide Y receptor 0.0429 0.1375 0.1478
Brugia malayi Smad1 0.005 0.0111 0.0111
Onchocerca volvulus 0.0039 0.0073 0.0292
Trypanosoma brucei C-8 sterol isomerase, putative 0.263 0.8722 1
Echinococcus granulosus BC026374 protein S09 family 0.0024 0.0022 0.0023
Schistosoma mansoni lamin 0.0113 0.032 0.0344
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.01 0.0277 0.0479
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0021 0.0072
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0024 0.0022 0.0023
Loa Loa (eye worm) carboxylesterase 0.014 0.0409 0.0409
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0177 0.0535 0.1919
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.0028 0.0625
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0389 0.1241 0.6575
Loa Loa (eye worm) ACC-1 protein 0.0018 0.0004 0.0004
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.02 0.07
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0164 0.0571
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0039 0.0073 0.0084
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Brugia malayi mbt repeat family protein 0.0052 0.0115 0.0115
Brugia malayi ERG2 and Sigma1 receptor like protein 0.263 0.8722 0.8722
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0047 0.0099 0.0107
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0099
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0051 0.0051
Echinococcus multilocularis para nitrobenzyl esterase 0.0024 0.0022 0.0023
Schistosoma mansoni twik family of potassium channels-related 0.0039 0.0073 0.0078
Mycobacterium ulcerans pyruvate kinase 0.0066 0.0164 0.0591
Echinococcus multilocularis cpg binding protein 0.003 0.0042 0.0045
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0051 0.0112 0.0193
Echinococcus multilocularis 0.0051 0.0112 0.012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0022
Echinococcus granulosus flap endonuclease 1 0.0054 0.0123 0.0132
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0176 0.0531 0.2773
Plasmodium falciparum glutathione reductase 0.0026 0.0028 0.0625
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0164 0.0677
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0168 0.0505 0.0875
Leishmania major hypothetical protein, conserved 0.0039 0.0073 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.1375 0.1478
Echinococcus granulosus tm gpcr rhodopsin 0.0937 0.3072 0.3302
Echinococcus granulosus nAChR subunit 0.0018 0.0004 0.0004
Schistosoma mansoni smad1 5 8 and 0.005 0.0111 0.0119
Loa Loa (eye worm) flap endonuclease-1 0.0054 0.0123 0.0123
Mycobacterium ulcerans hypothetical protein 0.0037 0.0065 0.0233
Loa Loa (eye worm) pyruvate kinase-PB 0.0046 0.0097 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0051 0.0055
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0429 0.1375 0.1478
Echinococcus granulosus cpg binding protein 0.003 0.0042 0.0045
Loa Loa (eye worm) hypothetical protein 0.0091 0.0247 0.0247
Echinococcus granulosus cytochrome P450 2K1 0.0051 0.0112 0.012
Onchocerca volvulus 0.0728 0.2373 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0047 0.0099 0.0099
Echinococcus granulosus hypothetical protein 0.0429 0.1375 0.1478
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.003 0.0044 0.0051
Brugia malayi hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) MH1 domain-containing protein 0.0022 0.0018 0.0018
Brugia malayi Cytochrome P450 family protein 0.0086 0.0231 0.0231
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0073 0.1605
Schistosoma mansoni caspase-3 (C14 family) 0.0019 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0033 0.0053 0.0057
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0168 0.0505 0.0875
Schistosoma mansoni neuropeptide F-like receptor 0.0429 0.1375 0.1478
Schistosoma mansoni biogenic amine (5HT) receptor 0.0796 0.26 0.2795
Echinococcus multilocularis neuropeptide receptor A26 0.0429 0.1375 0.1478
Giardia lamblia Hypothetical protein 0.0039 0.0073 0.0322
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0054 0.0123 0.0141
Onchocerca volvulus 0.0429 0.1375 0.5788
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) CYP4Cod1 0.0086 0.0231 0.0231
Brugia malayi glutathione reductase 0.0074 0.0189 0.0189
Schistosoma mansoni biogenic amine receptor 0.0429 0.1375 0.1478
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0051 0.0112 0.0401
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.0078 0.0203 0.0233
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0051 0.0112 0.0401
Schistosoma mansoni hypothetical protein 0.0039 0.0073 0.0078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.263 0.8722 0.8722
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0429 0.1375 0.1375
Brugia malayi Tachykinin-like peptides receptor 99D 0.0429 0.1375 0.1375
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Brugia malayi jmjC domain containing protein 0.0123 0.0354 0.0354
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0018 0.0004 0.0004
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0191 0.0205
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0018 0.0004 0.0004
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0041 0.0081 0.1795
Onchocerca volvulus 0.0429 0.1375 0.5788
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0004 0.0004
Echinococcus granulosus g-protein coupled receptor 0.0429 0.1375 0.1478
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0021 0.0024
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0053 0.0118 0.2616
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0051 0.0055
Trypanosoma brucei glucosidase, putative 0.0035 0.006 0.0068
Leishmania major DNA polymerase eta, putative 0.0021 0.0013 0.0015
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.0028 0.0032
Echinococcus granulosus somatostatin receptor 0.0429 0.1375 0.1478
Onchocerca volvulus Cell death protein 3 homolog 0.0097 0.0268 0.1115
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0053 0.0057
Onchocerca volvulus 0.0039 0.0073 0.0292
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0051 0.0055
Mycobacterium ulcerans carboxylesterase, LipT 0.0024 0.0022 0.0075
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0113 0.032 0.0554
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0429 0.1375 0.1478
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0018 0.0004 0.0004
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Onchocerca volvulus 0.0429 0.1375 0.5788
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0177 0.0535 0.0614
Loa Loa (eye worm) hypothetical protein 0.0276 0.0865 0.0865
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0018 0.0004 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0028 0.0145
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0018 0.0004 0.0004
Schistosoma mansoni amine GPCR 0.0429 0.1375 0.1478
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.0238 0.0255
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0039 0.0073 0.0073
Chlamydia trachomatis pyruvate kinase 0.0066 0.0164 0.3615
Trypanosoma brucei metacaspase 5, putative 0.0019 0.0007 0.0008
Echinococcus multilocularis serotonin receptor 0.1787 0.5909 0.6352
Trichomonas vaginalis set domain proteins, putative 0.0728 0.2373 0.8594
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0429 0.1375 0.1478
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1641 0.5423 0.9386
Onchocerca volvulus 0.0039 0.0073 0.0291
Echinococcus multilocularis rhodopsin orphan GPCR 0.0429 0.1375 0.1478
Onchocerca volvulus 0.0429 0.1375 0.5788
Echinococcus multilocularis thioredoxin glutathione reductase 0.0075 0.0193 0.0207
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0013 0.0021
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0152 0.0452 0.1634
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0019 0.0007 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Echinococcus multilocularis BC026374 protein (S09 family) 0.0024 0.0022 0.0023
Echinococcus granulosus neuropeptide FF receptor 2 0.0429 0.1375 0.1478
Loa Loa (eye worm) G-protein coupled receptor 0.0429 0.1375 0.1375
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0187 0.0568 0.0983
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0004 0.0004
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.0115 0.0124
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.02 0.072
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.02 0.0214
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0013 0.0015
Brugia malayi hypoxia-induced factor 1 0.0148 0.0437 0.0437
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0022 0.0023
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0429 0.1375 0.1375
Mycobacterium leprae Conserved hypothetical protein 0.0623 0.2022 1
Brugia malayi CAAX amino terminal protease family protein 0.0177 0.0535 0.0535
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0051 0.1131
Echinococcus multilocularis neuropeptides capa receptor 0.0429 0.1375 0.1478
Brugia malayi jmjC domain containing protein 0.0032 0.0051 0.0051
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0047 0.0099 0.22
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.0115 0.0124
Schistosoma mansoni caspase-7 (C14 family) 0.0097 0.0268 0.0288
Trichomonas vaginalis flap endonuclease-1, putative 0.0054 0.0123 0.042
Plasmodium falciparum metacaspase-like protein 0.0019 0.0007 0.0152
Brugia malayi jmjC domain containing protein 0.0032 0.0051 0.0051
Mycobacterium tuberculosis Probable dehydrogenase 0.0168 0.0505 0.0875
Entamoeba histolytica pyruvate kinase, putative 0.0046 0.0097 0.0452
Entamoeba histolytica hypothetical protein 0.0074 0.0191 0.0955
Giardia lamblia Hypothetical protein 0.0177 0.0535 0.2797
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0056 0.1247
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0111 0.0312 0.1603
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0111 0.0312 0.1603
Trichomonas vaginalis glucosylceramidase, putative 0.0278 0.0872 0.3142
Loa Loa (eye worm) MH2 domain-containing protein 0.0738 0.2407 0.2407
Brugia malayi glutaminase DH11.1 0.0844 0.276 0.276
Schistosoma mansoni neuropeptide receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0055 0.0125 0.0125
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0018 0.0004 0.0004
Schistosoma mansoni twik family of potassium channels-related 0.0039 0.0073 0.0078
Schistosoma mansoni biogenic amine receptor 0.0429 0.1375 0.1478
Echinococcus granulosus caspase 0.0019 0.0007 0.0007
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0276 0.0865 0.0865
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0553 0.1982
Toxoplasma gondii hypothetical protein 0.0037 0.0065 0.144
Echinococcus granulosus pyruvate kinase 0.0066 0.0164 0.0176
Echinococcus multilocularis sex peptide receptor 0.0429 0.1375 0.1478
Loa Loa (eye worm) hypothetical protein 0.0176 0.0531 0.0531
Schistosoma mansoni BC026374 protein (S09 family) 0.0024 0.0022 0.0023
Loa Loa (eye worm) MH2 domain-containing protein 0.005 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0073
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.0115 0.0472
Onchocerca volvulus 0.002 0.0009 0.0023
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) 0.0078 0.0203 0.0352
Echinococcus granulosus Smad4 0.005 0.0111 0.0119
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Brugia malayi NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor 0.0078 0.0203 0.0203
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0047 0.0099 0.0099
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.0115 0.0124
Loa Loa (eye worm) hypothetical protein 0.0429 0.1375 0.1375
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.01 0.0277 0.1278
Brugia malayi MH2 domain containing protein 0.005 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0091 0.0247 0.0247
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.02 0.0345

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0657 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.3696 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 1.9953 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488939] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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